All Products

Catalog No. Product Name Information
S8880 Lobaplatin (D-19466) Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent. It is a platinum complex with DNA alkylating activity.
S5614 (+)-Longifolene (+)-Longifolene is a naturally occurring, oily liquid hydrocarbon found primarily in the high-boiling fraction of certain pine resins
S3998 (+)-α-Lipoic acid (+)-α-Lipoic acid ((R)-(+)-α-Lipoic acid, α-Lipoic acid, Alpha-Lipoic acid), a physiological form of thioctic acid, is a strong antioxidant that relieves diabetic neuropathic symptoms. It shows superior antioxidative effects to its racemate. R(+)-α-lipoic acid is an essential cofactor of mitochondrial enzyme complexes. R(+)-α-lipoic acid inhibits NF-κB-dependent HIV-1 LTR activation.
E2549 (-)-Licarin B (-)-Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway.
S3329 (L)-Dehydroascorbic acid

(L)-Dehydroascorbic acid (DHA) is an oxidized form of l-Ascorbic acid (AsA) that efficiently scavenges non-thermal plasma-induced hydroxyl radicals in the presence of thiols and fails to scavenge hydroxyl radicals by itself.

S0102 L 189 L 189 is a novel human DNA ligase inhibitor with IC50 of 5 μM, 9 μM and 5 μM for hLigI, hLigIII and hLigIV, respectively. L 189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ). L 189 specifically sensitizes cancer cells to DNA damage.
S4950 L(+)-Asparagine monohydrate L-asparagine is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue, being used for a variety of pharmaceutical applications.
E0152 L(+)-Monosodium glutamate monohydrate

L(+)-Monosodium glutamate monohydrate (MSG monohydrate, L-Glutamic acid monosodium salt monohydrate, Monosodium L-glutamate monohydrate, Monosodium L-glutamate monohydrate) is a widespread nutritional additive and flavoring agent. L(+)-Monosodium glutamate monohydrate can lead to oxidative stress-mediated DNA damage and apoptosis.

E0989 L(-)-Anabasine

L(-)-Anabasineis an alkaloid that found as a minor component in tobacco.

S6302 L(-)-Pipecolinic acid L(-)-Pipecolinic acid (L-Homoproline) is a normal human metabolite present in human blood.
S5338 L(-)-Sorbose L(-)-Sorbose (L(-)-Sorbopyranose) is a ketose sugar that is commonly used in the commercial synthesis of ascorbic acid.
S6346 L-(+)-Arabinose L-(+)-Arabinose (DL-Arabinose, Pectinose) is used as a substrate to identify, differentiate and characterize pentose sugar isomerase(s).
E2759 L-(+)-Ergothioneine

L-(+)-Ergothioneine (Ergothioneine), an imidazole-2-thione derivative of histidine betaine synthesized by certain bacteria and fungi, is generally considered an antioxidant.

S2317 L-(+)-Rhamnose Monohydrate L(+)-Rhamnose (Rham) is a naturally-occurring deoxy sugar that is found primarily in plants and some bacteria.
S3131 L-(-)-Glucose

L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose promotes food intake while cannot be used by cells as an energy source because it cannot be phosphorylated by hexokinase.

S5954 L-(-)-α-Methyldopa hydrate L-(-)-α-Methyldopa (Methyldopa, MK-351) hydrate, a potent antihypertensive drug, is a selective agonist for α2-adrenergic receptors.
S1325 L-2-Hydroxyglutaric acid disodium

L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG) is an epigenetic modifier and a putative oncometabolite in kidney cancer that inhibits histone demethylases and hence promotes histone methylation. L-2-Hydroxyglutaric acid disodium is also an inhibitor of mitochondrial creatine kinase (Mi-CK) with Km and Ki of 2.52 mM and 11.13 mM, respectively.

S4769 L-5-Hydroxytryptophan 5-Hydroxytryptophan (5-HTP, L-oxitriptan), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.
S5264 L-5-Methyltetrahydrofolate calcium Calcium L-5-methyltetrahydrofolate (L-5-MTHF-Ca) is a synthetic derivative of folic acid, the predominant, naturally occurring form of folate.
S7673 L-685,458 L-685,458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.
S0772 L-732138 L-732138 (L-732,138) is a selective, potent and competitive antagonist of neurokinin-1 (NK-1) receptor/substance P (SP) receptor. L-732138 inhibits the binding of 125I-SP to the human NK-1 receptor stably expressed in CHO cells with IC50 of 2.3 nM.
S0774 L-745870 L-745870 is a high-affinity, selective and orally active antagonist of human dopamine D4 receptor with Ki of 0.43 nM. L-745870 considerably weaker D2 and D3 receptors affinity with Ki of 960 nM and 2300 nM, respectively. L-745870 has excellent brain penetration.
S0862 L-765314 L-765314 is a selective and potent α1b-adrenoceptor (α1b adrenergic receptor) antagonist with an IC50 of 1.90 nM and Kis of 5.4 and 2.0 for rat and human α1b adrenergic receptor, respectively.
S6680 L-779450 L-779450 is a highly potent low nanomolar inhibitor of B-raf with IC50 of 10 nM and Kd of 2.4 nM.
S5828 L-Abrine L-Abrine (N-Methyl-L-tryptophan), an extremely toxic toxalbumin found in the seeds of the rosary pea, is a ribosome inhibiting protein.
S2522 L-Adrenaline L-Adrenaline (Epinephrine) belongs to a group of the compounds known as catecholamines.
S5631 L-Alanine Alanine is a naturally occuring non-essential amino acid that is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brainR, and the CNS.
E0134 L-Albizziin

L-albizziin (L-alpha-amino-beta-ureidopropionic acid) is a potent inhibitor of glutamase. L-albizziin interferes with the utilisation of L-glutamine by the Debaryomyces spp. enzyme probably in a competitive and reversible manner since L-albizziin is also a substrate of the enzyme.

S3266 L-Anserine nitrate salt

L-Anserine nitrate salt, a dipeptide found in most animal tissues, exhibits antioxidant properties, anti-crosslinking, and anti-glycation activities. L-Anserine protects against neurotoxicity induced by ER-stress inducers.

S6045 L-Arabinitol L-Arabinitol (L-lyxitol) is a member of the class of compounds known as sugar alcohols that exists in all living species, ranging from bacteria to humans. It can be found in a number of food items such as sweet potato, deerberry, moth bean, and European chestnut, which makes L-arabitol a potential biomarker for the consumption of these food products.
S3986 L-Arabinose L-Arabinose (L-Ara) is a plant saccharide that is not found in animals. It is a component of cell wall and may be useful as a natural pharmaceutical.
S5634 L-arginine Arginine is an important amino acid used in the biosynthesis of proteins. L-arginine plays an important role in immune regulation by affecting the immune response and inflammation. It is also implicated in cell division, wound healing and the release of hormones.
S3174 L-Arginine HCl (L-Arg) L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
E2692 L-Ascorbic acid 2-phosphate sesquimagnesium salt L-Ascorbic acid 2-phosphate sesquimagnesium salt (2-Phospho-L-ascorbic acid magnesium), a long-acting vitamin C derivative that can stimulate collagen formation and expression, can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs), which increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation.
S2532 L-Ascorbyl 6-palmitate Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C.
S5571 L-Asparagine L-Asparagine (2-Aminosuccinamic acid, alpha-aminosuccinamic acid) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
S5632 L-aspartic Acid L-aspartic Acid is one of non-essential amino acids and may be a neurotransmitter.
S2388 L-carnitine L-carnitine (Levocarnitine) is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
S5922 L-Carnitine hydrochloride L-Carnitine ((R)-Carnitine, Levocarnitine) hydrochloride improves oxygen saturation, and inhibits leukotriene synthesis. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation.
S5226 L-carnosine L-carnosine (Karnozin) is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress.
S3798 L-Citrulline L-citrulline is a substance called a non-essential amino acid that is used as a sports performance and cardiovascular health supplement.
S3945 L-Cycloserine L-Cycloserine (Levcycloserine, Levcicloserina, Levcycloserinum, (-)-Cycloserine, (S)-Cycloserine) is a potent inhibitor of the sphingolipid pathway via inhibiting 3-ketodihydrosphingosine synthetase. It also inhibits HIV-1 cytopathic effects, replication, and infectivity.
S3325 L-Cysteic acid monohydrate

L-Cysteic acid monohydrate (CAM) is an active endogenous metabolite.

S5635 L-cysteine Cysteine is a naturally occurring, sulfur-containing amino acid which is important for protein synthesis, detoxification, and also exerts diverse metabolic functions.
S4815 L-Cysteine HCl L-cysteine Hydrochloride, also known as L-CYSTEINE or Cysteine HCL (anhydrous), is classified as a cysteine or a cysteine derivative that increases glutathione levels and is important for lung and brain function and liver detoxification.
S4808 L-Cystine L-Cystine is the oxidized dimer form of the amino acid L-cysteine which is a non-essential amino acid of the human body. It is required for wound healing and formation of epithelial tissue.

L-DAB HBR (L-Dab Hydrobromide, L-2,4-Diaminobutyric acid hydrobromide) is an inhibitor of GABA (Gamma-aminobutyric acid) transaminase with IC50 of >500 μM. L-DAB HBR exhibits antitumor activity.

S3230 L-Fucitol L-Fucitol (1-Deoxy-D-galactitol), a galactitol analogue isolated from Myristica fragrans (Nutmeg), inhibits galactitol-positive strains of Escherichia coli K12.
S9002 L-Fucose Fucose (6-Deoxy-L-Galactose, L-fucopyranose) is found on N-linked glycans on the mammalian, insect and plant cell surface. L-Fucose is claimed to have application in cosmetics, pharmaceuticals, and dietary supplements.
S4721 L-Glutamic acid monosodium salt L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods. L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
S1749 L-Glutamine L-Glutamine (Gln) is one of the 20 amino acids encoded by the standard genetic code and also a major respiratory fuel and substrate for nucleic acid synthesis in mammalian intestinal cells.
S6182 L-Gulono-1,4-lactone L-Gulono-1,4-lactone (L-Gulonolactone, L-Gulono-gamma-lactone, reduced ascorbic acid) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic acid (vitamin C) in plants and animals.
S6180 L-Gulose L-Gulose is an unnatural monosaccharide that exists as a syrup with a sweet taste. It is an L-hexose sugar and an intermediate in the biosynthesis of L-Ascorbate (vitamin C).
S3096 L-Histidine monohydrochloride monohydrate

L-Histidine monohydrochloride monohydrate (L-Histidine hydrochloride hydrate, H-His-OH.HCl.H2O), a structural analogue of the essential amino acid L-histidine, is a reversible inhibitor of protein biosynthesis which evokes disparate responses from non-tumorigenic and tumorigenic cells in culture.

S3337 L-Histidinol dihydrochloride

L-Histidinol dihydrochloride, a structural analogue of the essential amino acid L-histidine, is a reversible inhibitor of protein biosynthesis which evokes disparate responses from non-tumorigenic and tumorigenic cells in culture.

S5431 L-Homoarginine hydrochloride L-Homoarginine is a specific inhibitor of liver-type alkaline phosphatase.
S6128 L-Homocitrulline L-Homocitrulline (N(6)-carbamoyl-L-lysine) is an amino acid and a metabolite of ornithine in mammalian metabolism.
S3118 L-Homoserine

L-Homoserine (L-Hse) is an important biosynthetic intermediate of threonine, methionine and lysine.

S6111 L-Hydroorotic acid L-Dihydroorotic acid (L-dihydroorotate) is an intermediate in the metabolism of Pyrimidine. It is a substrate for Dihydroorotate dehydrogenase (mitochondrial).
S5820 L-Hydroxyproline L-Hydroxyproline (trans-4-Hydroxy-L-proline) is a collagen-specific amino acid. It is used as a diagnostic marker of bone turnover and liver fibrosis.
E2740 L-Isopulegol

L-Isopulegol ((-)-Isopulegol; Isopulegol) is a p-menthane monoterpenoid found in <i>Teucrium divaricatum</i>, <i>Teucrium cyprium</i>.

S5839 L-Kynurenine L-Kynurenine ((S)-Kynurenine) is a aryl hydrocarbon receptor agonist. L-Kynurenine is a metabolite of the amino acid L-tryptophan used in the production of niacin and a central compound of the tryptophan metabolism pathway.
S6250 L-Lactic acid L-Lactic acid is a natural product that is used as a food additive.
S3753 L-Leucine Leucine ((S)-Leucine, Leu) is one of nine essential amino acids in humans which is important for protein synthesis and many metabolic functions. It contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.
S6153 L-Leucyl-L-alanine Hydrate L-Leucyl-L-alanine Hydrate (H-Leu-Ala-OH) is a dipeptide composed of L-leucine and L-alanine joined by a peptide linkage. It is a metabolite.
S5630 L-lysine Lysine is an α-amino acid that is used in the biosynthesis of proteins and is required for growth and tissue repair.
S3953 L-Lysine hydrochloride L-Lysine hydrochloride is an essential amino acid. It is often added to animal feed used as a dietary supplement and plays a major role in calcium absorption, building muscle protein, recovering from surgery or sports injuries, and the body's production of hormones, enzymes, and antibodies.
S5633 L-methionine L-Methionine is an essential sulfur-containing, free-form amino acid, acts as an antioxidant promoter, and contributes to the synthesis of S-adenosyl-L-methionine (SAMe).
S7446 L-Mimosine L-Mimosine (Leucenol) is a non-protein amino acid, and acts as an iron chelator.
S2877 L-NAME HCl L-NAME HCl (NG-Nitroarginine methyl ester, N-Nitro-L-arginine methylester) is a nonselective inhibitor of nitric oxide synthetases (NOS) for nNOS (bovine), eNOS (human), and iNOS (murine), with Ki of 15 nM, 39 nM and 4.4 μM, respectively.
S7920 L-NMMA acetate L-NMMA acetate (Tilarginine Acetate, Methylarginine acetate, NG-Monomethyl-L-arginine acetate, L-NG-monomethyl Arginine acetate) is an acetate salt form of L-NMMA. L-NMMA is a nitric oxide synthase(NOS) inhibitor with an IC50 of 4.1 μM for nNOS.
S4857 L-Ornithine L-ornithine ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.
S4653 L-Ornithine hydrochloride L-ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.
S4745 L-Phenylalanine L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.
S5629 L-Proline L-Proline is one of non-essential amino acids and an essential component of collagen that is important for proper functioning of joints and tendons.
S5823 L-Pyroglutamic acid L-pyroglutamic acid (L-pyroglutamate, 5-Oxoproline, pidolic acid) is a natural nutrient and amino acid derived from glutamic acid. It is a metabolite in the glutathione cycle that is converted to glutamate by 5-oxoprolinase.
S3223 L-Quebrachitol L-Quebrachitol (L-QCT), a natural product isolated from many plants, promotes proliferation and cell DNA synthesis. L-Quebrachitol upregulates bone morphogenetic protein-2 (BMP-2) and runt-related transcription factor-2 (Runx2) and regulatory genes associated with mitogen-activated protein kinase (MAPK) and Wnt/β-catenin signaling pathway, while down-regulating the receptor activator of the nuclear factor-κB(NF-κB) ligand (RANKL) mRNA level.
S3973 L-SelenoMethionine L-SelenoMethionine (SeMet), a naturally occurring amino acid, is a major food-form of selenium. It has been used as a supplement, and exhibits some important functions like cancer prevention and antioxidative defense.
S9353 L-serine L-serine, one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
S3852 L-Theanine L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.
S6312 L-Threonic acid Calcium Salt L-Threonic acid Calcium Salt (Calcium threonate) is a calcium salt of threnoic acid. L-Threonic acid is a metabolite of ascorbic acid (vitamin C).
S4951 L-Threonine L-Threonine is an essential amino acid which is in its active form. It is important for the formation of collagen, elastin, and tooth enamel, and aids liver and lipotropic function when combined with aspartic acid and methionine.
S2599 L-Thyroxine L-Thyroxine (NSC 36397,Levothyroxine) is a synthetic form of thyroxine and a hormone replacement drug.
S5193 L-Thyroxine sodium salt pentahydrate L-Thyroxine (Levothyroxine, L-T4) sodium salt pentahydrate is a synthetic T4 hormone used to counterbalance hypothyroidism.
S3987 L-Tryptophan L-tryprophan is an essential amino acid that acts like a natural mood regulator that is necessary for normal growth in infants and for nitrogen balance in adults.
S6155 L-Tryptophanamide Hydrochloride L-tryptophanamide (H-Trp-NH2) is an amino acid amide that is the carboxamide of L-tryptophan.
S4608 L-Tyrosine L-tyrosine ((S)-Tyrosine, P-Tyrosine, L-p-Tyrosine) is a non-essential amino acid. In animals it is synthesized from Ephenylalanine.
S5628 L-Valine Valine is a branched-chain essential amino acid that has stimulant activity and promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
S5830 L-Xylose L-Xylose is a synthesized levorotary form of Xylose, a sugar first isolated from wood.
S3989 L-​Histidine L-​Histidine (Glyoxaline-5-alanine) is an α-amino acid needed in humans for growth and tissue repair. It is used in the biosynthesis of proteins.
E0405 L002 (NSC764414) L002 (NSC764414) is a potent, cell permeable, reversible and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM.
A5289 L1CAM Rabbit Recombinant mAb L1CAM Rabbit Recombinant mAb detects endogenous level of total L1CAM.
S7974 L755507 L-755,507 is characterized as a potent and selective β3 adrenergic receptor partial agonist with EC50 of 0.43 nM. It is also recently identified to enhance CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs) and other cell types.
S4291 Labetalol HCl Labetalol HCl(AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W) is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.
S5088 Labetalone hydrochloride Labetalone hydrochloride (Benzoic amide) is hydrochloride form of labetalone, a blocker of both alpha- and beta-adrenergic receptors that is used as an antihypertensive.
S1994 Lacidipine Lacidipine (GX-1048, GR-43659X, SN-305) is a L-type calcium channel blocker, used for treating high blood pressure.
S5368 Lactitol Lactitol is a versatile, reduced calorie sweetener derived from natural milk sugar, used in a wide variety of sweetening applications.
S5282 Lactitol monohydrate Lactitol is an artificial sugar alcohol currently used as a bulk sweetener in calorie-controlled foods.
S4964 Lactobionic acid Lactobionic acid (Galactosylgluconic acid), an α-hydroxyacid (AHA) with antioxidation activity, is used in the development of cosmeceuticals for skin. Lactobionic acid inhibits matrix-metalloproteinase (MMP) activity.
A5300 Lactoferrin Rabbit Recombinant mAb Lactoferrin Rabbit Recombinant mAb detects endogenous level of total Lactoferrin.
S6047 Lactose Lactose is a disaccharide naturally found in milk and dairy.
E3717 Lactuca sativa Extract
E0570 Lactucine

Lactucin, a naturally occurring active sesquiterpene lactone found in chicory and romaine lettuce, induces apoptosis in leukemia cells.

S1511 Lactulose Lactulose, a disaccharide composed of galactose and fructose, is a stimulator of health-promoting bacterium growth in the gastrointestinal tract, used to treat chronic constipation and hepatic encephalopathy.
S1263 Laduviglusib (CHIR-99021) Laduviglusib (CHIR-99021, CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. CHIR99021 functions as a Wnt/β-catenin activator and induces autophagy.
S2924 Laduviglusib (CHIR-99021) HCl Laduviglusib (CHIR-99021; CT99021) HCl is hydrochloride of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; CHIR-99021 shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2. CHIR-99021 is a potent pharmacological activators of the Wnt/beta-catenin signaling pathway. CHIR-99021 significantly rescues light-induced autophagy and augments GR, RORα and autophagy-related proteins.
S2065 Lafutidine Lafutidine (FRG-8813), a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.
E3709 Lagotis glauca Extract
E2815 Lalistat 2 Lalistat 2 is a specific inhibitor of lysosomal acid lipase (LAL) which allows the determination of LAL in dried blood spots (DBS).
A5513 Lamin B Receptor Rabbit Recombinant mAb Lamin B Receptor Rabbit Recombinant mAb detects endogenous level of total Lamin B Receptor.
A5106 Lamin B1 Rabbit Recombinant mAb Lamin B1 Rabbit Recombinant mAb detects endogenous levels of total Lamin B1.
E3244 Laminaria Japonica Extract
A5453 Laminin beta 1 Rabbit Recombinant mAb Laminin beta 1 Rabbit Recombinant mAb detects endogenous level of total Laminin beta 1.
E3171 Lamiophlomis Herba Extract
S1706 Lamivudine (BCH-189) Lamivudine (BCH-189, GR109714X) is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS. It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase.
S3024 Lamotrigine Lamotrigine (BW-430C) is a novel anticonvulsant drug for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, and also is a sodium channel blocker.
S8193 Lanabecestat (AZD3293) Lanabecestat (AZD3293, LY3314814) is an oral beta-secretase 1 cleaving enzyme (BACE) inhibitor with an inhibitory constant Ki  of 0.4 nM.
S5554 Lanatoside C Lanatoside C is a cardiac glycoside with antiviral and anti-tumor activity. Lanatoside C induces G2/M cell cycle arrest and induces autophagy and apoptosis via attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR signaling pathways.
S5540 Landiolol hydrochloride Landiolol hydrochloride (ONO-1101) is the hydrochloride salt form of Landiolol, which is an ultra-short-acting β1 selective adrenoceptor antagonist.
S8770 Lanifibranor (IVA-337) Lanifibranor (IVA-337) is a moderately potent and well balanced pan PPAR agonist with EC50 values of 1537 nM, 866 nM and 206 nM for hPPARα, hPPARδ and hPPARγ, respectively.
S0861 Laninamivir Octanoate Laninamivir octanoate (CS-8958, R-118958, Inavir, LANI), a prodrug of Laninamivir (R-125489), is a long-acting neuraminidase (NA) inhibitor with superior anti-influenza virus activity.
S5106 Lanolin Lanolin (wool wax, wool grease) is a wax secreted by the sebaceous glands of wool-bearing animals and used widely in the pharmaceutical and cosmetics industries.
S4755 lanosterol Lanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast plant steroids are produced via cycloartenol.
S9715 Lanraplenib (GS-9876) Lanraplenib (GS-9876, GS-SYK) is a potent, highly selective and orally active inhibitor of Spleen Tyrosine Kinase (SYK) with IC50 of 9.5 nM. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.
S6948 Lanreotide

Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum), an analog of the native somatostatin peptide, is a physiological inhibitor of growth hormone (GH). Lanreotide also has antitumoral effects.

P1088 Lanreotide acetate

Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum) acetate, an analog of the native somatostatin peptide, is a physiological inhibitor of growth hormone (GH). Lanreotide also has antitumoral effects.

S1354 Lansoprazole Lansoprazole (A-65006, AG-1749) is a proton-pump inhibitor (PPI) that binds covalently to parietal cell H(+),K(+)-ATPase. Lansoprazole prevents the stomach from producing gastric acid.
S5514 Lanthanum(III) chloride heptahydrate Lanthanum(III) chloride is the inorganic compound used in biochemical research to block the activity of divalent cation channels, mainly calcium channels.
S5684 Lapachol Lapachol (Tecomin, CI75490, Bethabarra wood, Greenhartin), a natural compound isolated from the bark of the lapacho tree, shows both antimicrobial and antiviral activity.
S2111 Lapatinib (GW-572016) Lapatinib (GW-572016, GSK572016, GW2016), used in the form of Lapatinib Ditosylate, is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. Lapatinib induces ferroptosis and autophagic cell death.
S1028 Lapatinib (GW-572016) Ditosylate Lapatinib (GW-572016) Ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively.
S5241 Lapatinib ditosylate monohydrate Lapatinib ditosylate monohydrate (Lapatinib ditoluenesulfonate monohydrate, Lapatinib tosilate, Lapatinib tosilate hydrate)is a dual tyrosine kinase inhibitor which interrupts the HER2/neu and epidermal growth factor receptor (EGFR) pathways, used for treatment of solid tumours such as breast and lung cancer.
S2387 Lappaconite HBr Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.
S2318 Lappaconitine Lappaconitine (LC) is a natural diterpenoid alkaloid (DTA), acting as a human heart sodium channel blocker and possessing a wide range of biological activities, including anti-arrhythmic, anti-inflammatory, antioxidative, anticancer, epileptiform etc.
S2787 Laquinimod Laquinimod (ABR-215062, LAQ) is a potent immunomodulator. Phase 3.
E2035 Larazotide Larazotide(AT-1001) is an antagonist of Zonulin, which appears safe and well-tolerated and may offer potential benefit as an adjuvant to immune-targeted therapies.
E3566 Largeleaf Gentian Root Extract
E2725 Larixyl acetate

Larixyl acetate, a main constituent of larch resin, is able to selectively inhibit <b>TRPC6</b> function.

S5860 Larotrectinib Larotrectinib (Vitrakvi, LOXO-101, ARRY-470) is an ATP-competitive, oral administered and highly selective inhibitor of the tropomyosin-related kinase (TRK) family receptors.
S7960 Larotrectinib (LOXO-101) sulfate Larotrectinib sulfate (LOXO-101, ARRY-470) is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK). Larotrectinib inhibition of TRKs induces cellular apoptosis and G1 cell-cycle arrest.
E3337 Larva of a Silkworm with Batrytis Extract
S5064 Lasmiditan Lasmiditan (Reyvow) is a highly selective 5-hydroxytryptamine (serotonin) receptor 1F (5-HT1F) agonist that can be used as a promising acute anti-migraine therapy.
S6489 Lasmiditan succinate Lasmiditan succinate (COL-144, LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (Ki=2.21 nM) without vasoconstrictor activity.
S9520 Lasofoxifene Tartrate Lasofoxifene Tartrate is a third-generation, non-steroidal selective estrogen receptor modulator (SERM) which binds with high affinity to the human estrogen receptor-α with IC50 value of 1.5 nM.
S4986 Latamoxef sodium Latamoxef sodium (Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S) is an antibiotic and has anti-bacterial and anti-inflammation effects.
S4709 Latanoprost Latanoprost (Xalatan, PhXA41) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.
S3921 Lathyrol Lathyrol is a natural product that is used for cancer treatment.
E3388 Latifolin Extract
S1245 Latrepirdine 2HCl Latrepirdine is an orally active,and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.
S0477 LAU159 LAU159 is a potent functionally selective positive modulator of α1β3 GABA(A) receptor with EC50 of 2.2 μM.
S4726 Lauric Acid Lauric Acid (dodecanoic acid, N-Dodecanoic acid, Dodecylic acid) is a saturated medium-chain fatty acid with a 12-carbon backbone. Lauric acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
S4841 Laurocapram Laurocapram (N-Dodecylcaprolactam, Azone, N-0252, N-Lauryl caprolactam, Tranzone) is a skin penetration enhancer that facilitates absorption of cutaneously applied substances.
E2538 Laurolitsine Lancifoliaine is a bisbenzylisoquinoline from the bark of Litsea lancifolia.
S6229 Lauryl gallate Lauryl gallate (Dodecyl gallate) is the ester of dodecanol and gallic acid that exhibits both potent chain-breaking and preventive antioxidant activity.
E3792 Lavandula Angustifolia Extract
S0235 Lavendustin B Lavendustin B inhibits HIV-1 integrase (IN) interaction with its cognate cellular cofactor lens epithelium-derived growth factor (LEDGF/p75). Lavendustin B is an inhibitor of Tyrosine Kinase and also a competitive inhibitor of glucose transporter 1 (Glut1).
S3858 Lawsone Lawsone (Hennotannic acid, 2-hydroxy-1,4-naphthoquinone) is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).
S6422 Lazabemide Lazabemide (Ro 19-6327) is a reversible and selective inhibitor of monoamine oxidase B (MAO-B) with Ki value of 7.9 nM.
S8724 Lazertinib Lazertinib (YH25448,GNS-1480) is a potent, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively, showing much higher IC50 values aganist ErbB2 and ErbB4.
S7537 LB-100 LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
S7467 LB42708 LB42708 is an orally active farnesyltransferase (FTase) inhibitor with IC50 of 0.8, 1.2, and 2.0 nM toward H-ras, N-ras, and K-ras, respectively.
S6996 LC-2 LC-2 is a first PROTAC capable of degrading endogenous KRASG12C with DC50s between 0.25 μM and 0.76 μM. LC-2 covalently binds KRASG12C with a MRTX849 warhead and recruits the E3 ligase VHL, inducing rapid and sustained KRASG12C degradation leading to suppression of MAPK signaling.
S0658 LC-PEG8-SPDP LC-PEG8-SPDP is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0778 LC3-mHTT-IN-AN1 LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
A5202 LC3B Rabbit Recombinant mAb LC3B Rabbit Recombinant mAb detects endogenous level of total LC3B.
S1976 LCH-7749944 LCH-7749944 (GNF-PF-2356) is a novel and potent p21-activated kinase 4 (PAK4) inhibitor with an IC50 of 14.93 μM and has less potently inhibitory effect against PAK1, PAK5 and PAK6. LCH-7749944 causes successful inhibition of EGFR activity due to its inhibitory effect on PAK4.
S7009 LCL161 LCL-161, a small molecule second mitochondrial activator of caspase (SMAC) mimetic, potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP).
E2832 LCS-1 LCS-1 is an inhibitor of superoxide dismutase 1(SOD1) with IC50 of 1.07 μM.
S7461 LDC000067 LDC000067 (LDC067) is a highly selective CDK9 inhibitor with IC50 of 44 nM, 55/125/210/ >227/ >227-fold selectivity over CDK2/1/4/6/7.
S7638 LDC1267 LDC1267 is a highly selective TAM kinase inhibitor with IC50 of <5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8.
S9622 LDC7559 LDC7559 is a potent Gasdermin D(GSDMD) inhibitor inhibiting the pyroptosis and lessens its inflammation.
S3406 LDN-192960 LDN-192960 (Compd 1) is a potent inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50 of 10 nM and 48 nM, respectively.
S2618 LDN-193189 LDN-193189 (DM3189) is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. For animal testing, the water-soluble S7507 LDN-193189 2HCl is recommended.
S7507 LDN-193189 2HCl LDN-193189 (DM3189) 2HCl is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.
S7147 LDN-212854 LDN-212854 (BMP Inhibitor III) is a potent and selective BMP receptor inhibitor with IC50 of 1.3 nM for ALK2, about 2-, 66-, 1641-, and 7135-fold selectivity over ALK1, ALK3, ALK4, and ALK5, respectively.
S0460 LED209 LED209 is a potent, highly selective prodrug inhibitor of bacterial receptor QseC.
S7579 Ledipasvir (GS5885) Ledipasvir (GS5885) is a HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.
S4434 Ledipasvir acetone Ledipasvir (GS-5885) acetone is the active ingredient of Ledipasvir. Ledipasvir is a potent, oral active inhibitor of the hepatitis C virus (HCV) NS5A with EC50 of 31 pM and 4 pM against GT1a and GT1b replicon, respectively.
S3496 Lefamulin acetate (Xenleta) Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.
S1247 Leflunomide (HWA486) Leflunomide (HWA486, RS-34821, SU101, Arava) is a pyrimidine synthesis and protein tyrosine kinase inhibitor belonging to the DMARD, used as an immunosuppressant agent. The active metabolite of Leflunomide is A77 1726, which inhibits dihydroorotate dehydrogenase (DHODH). Leflunomide is also an agonist of the AhR.
S1029 Lenalidomide (CC-5013) Lenalidomide (CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis.
S1016 Lenalidomide-Br Lenalidomide-Br is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is that is applicable to the recruitment of CRBN protein. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs.
S8752 leniolisib (CDZ 173) Leniolisib (CDZ 173) is a potent PI3Kδ selective inhibitor with biochemical IC50 values of 0.244, 0.424, 2.23 and 0.011 μM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.
E3065 Lentil Extract
S5083 Lentinan Lentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.
S1164 Lenvatinib (E7080) Lenvatinib (E7080) is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β in cell-free assays. Lenvatinib (E7080) also inhibits FGFR1-4, PDGFR, Kit (c-Kit), RET (c-RET), and shows potent antitumor activities. Phase 3.
S5240 Lenvatinib (E7080) Mesylate Lenvatinib Mesylate (E7080) is a synthetic, orally available tyrosine kinase inhibitor that inhibits vascular endothelial growth factor receptor (VEGFR1-3), fibroblast growth factor receptor (FGFR1-4), platelet-derived growth factor receptor α (PDGFRα), stem cell factor receptor (Kit (c-Kit)), and rearranged during transfection (RET (c-RET)). Lenvatinib Mesylate has potential antineoplastic activity.
S9119 Leonuride Leonuride (Ajugol), an active alkaloid that is extracted from Traditional Chinese Medicine Herba leonuri, is a terpene glycoside that can be used for some gynecological disease.
S3890 Leonurine Leonurine, an active alkaloid extracted from Traditional Chinese Medicine Herba leonuri, exerts several biological effects, such as antidiabetic, cardiovascular, and bovine mastitis protection.
S9047 Leonurine Hydrochloride Leonurine (SCM-198), a natural alkaloid extracted from Herba leonuri, is a promising anti-glycation agent with vasodilator, antioxidative, cardioprotective and neuroprotective effects.
E3820 Leonurus Japonicus Extract
A5963 Leptin Receptor Rabbit Recombinant mAb Leptin Receptor Rabbit Recombinant mAb detects endogenous levels of total leptin receptor.
S7580 Leptomycin B Leptomycin B (LMB, CI 940, Elactocin, Mantuamycin, NSC 364372) is a potent antifungal antibiotic isolated from Streptomyces and acts as a specific inhibitor of the nuclear export factor CRM1. Leptomycin B rapidly induces cytotoxic effects in cancer cell lines via covalent inhibition of CRM1 with IC50 values of 0.1 nM–10 nM.
S5861 Lercanidipine Lercanidipine is a vasoselective dihydropyridine calcium antagonist used for the treatment of essential hypertension.
S4597 Lercanidipine hydrochloride Lercanidipine is a calcium channel blocker of the dihydropyridine class.
S2644 Lerisetron Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM.
A2040 Leronlimab (anti-CCR5) Leronlimab (anti-CCR5) (PRO 140; Vyrologix)is a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy. It is being investigated as a potential therapy in the treatment of HIV infection.
S8055 Lersivirine (UK-453061) Lersivirine (UK-453061) is a potent and selective inhibitor of nonnucleoside reverse transcriptase (NNRTI) with IC50 of 0.119 μM.
S4640 Lesinurad Lesinurad (RDEA-594) is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout in combination with xanthine oxidase inhibitors. Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.
S5189 Lesinurad sodium Lesinurad (Selexipag, RDEA-594) sodium (Zurampic) is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout. Lesinurad sodium inhibits the uric acid transporter URAT1 and Kidney transporter OAT with IC50/Km of 4.3 μM/0.85 μM and 3.5 μM/2 μM for OAT1 and OAT3, respectively.
S8873 Letermovir (AIC246) Letermovir (AIC246, MK-8228) is a novel anti-CMV compound which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors.
S1235 Letrozole (CGS 20267) Letrozole (CGS 20267) is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays.It has no effect on the plasma levels of 17α-OH progesterone, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies. Letrozole induces autophagy.
S6269 Leucomalachite green Leucomalachite green is a chief metabolite of malachite green, a triphenylmethane dye. It is one of the most commonly used reagents for presumptive blood test and gives a characteristic green color in the presence of blood.
E2326 Leucoside

Leucoside is a natural compound isolated from tea seed extract.

S1236 Leucovorin (NSC -3590) Calcium Pentahydrate Leucovorin Calcium Pentahydrate (NSC -3590, Folinic acid) is a derivative of folic acid, which can be used to increase levels of folic acid under conditions favoring folic acid inhibition.
S8306 Leukadherin-1 Leukadherin-1 (LA1) is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1(an agonist for the complement receptor 3 (CD11b/CD18)).
S7380 Leupeptin Hemisulfate Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases. It inhibits cathepsin B (Ki = 6 nM), calpain (Ki = 10 nM), trypsin (Ki = 35 nM), plasmin (Ki = 3.4 μM), and kallikrein (Ki = 19 μM), and has no effect against chymotrypsin, elastase, renin, or pepsin.
S3718 Leuprolide Acetate Leuprolide acetate (Leuprorelin) is a synthetic nonapeptide that is a potent gonadotropin-releasing hormone receptor (GnRHR) agonist used for diverse clinical applications, including the treatment of prostate cancer, endometriosis, uterine fibroids, central precocious puberty and in vitro fertilization techniques.
S3153 Levalbuterol tartrate Levalbuterol HCl is a relatively selective beta2-adrenergic receptor agonist used for the treatment of asthma.
S1939 Levamisole hydrochloride Levamisole, also known as (-)-Tetramisole, is an inhibitor of alkaline phosphatase, used as an anthelmintic.
S3674 Levamlodipine Levamlodipine (S-amlodipine) is a pharmacologically active enantiomer of amlodipine which belongs to the dihydropyridine group of calcium channel blocker. It acts on the L-type of calcium channels and its treatment results in vasodilation and a fall in blood pressure.
E0826 Levamlodipine Besylate Levamlodipine Besylate is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina.
S1356 Levetiracetam (UCB-L059) Levetiracetam (UCB-L059, SIB-S1) is an anticonvulsant medication used to treat epilepsy. Levetiracetam (UCB-L059, SIB-S1) is an agonist of muscarinic acetylcholine receptors (mAChR). Levetiracetam modulates the presynaptic P/Q-type voltage-dependent calcium (Ca2+) channel.
S9201 Levistilide A Levistilide A (Diligustilide), a natural compound isolated from the traditional Chinese herb Ligusticum chuanxiong Hort, is a potential P-gp modulator and used for treating cancer.
S4085 Levobetaxolol HCl Levobetaxolol (AL 1577A) exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively.
S5181 Levobupivacaine Levobupivacaine (Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine), the S (-)-enantiomer of bupivacaine, is a long-acting amide local anaesthetic used in analgesia and anaesthesia. Levobupivacaine exhibits effects on motor and sensory nerves by inhibiting the opening of voltage-gated sodium channels.
S4061 Levobupivacaine HCl Levobupivacaine HCl ((S)-(-)-Bupivacaine), the pure S(-)-enantiomer of bupivacaine, is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.
S5864 Levocetirizine Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.
S4849 Levocetirizine Dihydrochloride Levocetirizine (Xyzal, (-)-Cetirizine) is the active R-enantiomer of cetirizine and represents a new second-generation histamine H1 antagonist.
S1726 Levodopa Levodopa is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), used to treat Parkinson's symptoms.
S4131 Levodropropizine Levodropropizine possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.
S1940 Levofloxacin Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.
S4604 Levofloxacin hydrate Levofloxacin (Levaquin, Tavanic, Quixin, Iquix, Cravit) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. It acts by inhibiting DNA gyrase (bacterial topoisomerase II).
S3319 Levoglucosan

Levoglucosan (LG, LEV, Leucoglucosan, Glucosan, 1,6-anhydro-b-D-Glucose) is an endogenous metabolite.

S6909 Levomefolic acid Levomefolic acid (5-MTHF, LMSR, Metafolin, Nutrifolin) is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions.
S5693 Levomilnacipran Hydrochloride Levomilnacipran Hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor with antidepressant activity.
S1727 Levonorgestrel Levonorgestrel (D-Norgestrel) is a female hormone that prevents ovulation.
S2446 Levosimendan Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure.
S2104 Levosulpiride Levosulpiride(RV-12309,S-(-)-Sulpiride) is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent.
S3747 Levothyroxine sodium Levothyroxine (L-T4, L-Thyroxine) is the major hormone derived from the thyroid gland. It is the agonist of Thyroid hormone receptor alpha and beta.
S6207 Levulinic acid Levulinic acid (4-oxopentanoic acid, β-Acetylpropionic acid, 3-Acetopropionic acid, γ-ketovaleric acid) is used as a precursor for pharmaceuticals, plasticizers, and various other additives.
S2195 Lexibulin (CYT997) Lexibulin (CYT997, SRI-32007) is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines. Phase 2.
S7734 LFM-A13 LFM-A13 is a specific Bruton's tyrosine kinase (BTK) inhibitor with IC50 of 2.5 μM, >100-fold selectivity over other protein kinases including JAK1, JAK2, HCK, EGFR,and IRK.
S7143 LGK-974 LGK-974 (NVP-LGK974, WNT974) is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM in TM3 cells. Phase 1.
S0064 LHW090-A7 LHW090-A7 is an inhibitor of neutral endopeptidase (NEP) which is an enzyme responsible for the metabolic inactivation of enkephalins.
S6594 Liarozole dihydrochloride Liarozole Dihydrochloride is identified as a modest inhibitor of P450 with IC50 of 2.2–6.0 μM and 260 nM for CYP26 and rat CYP17 respectively.
S7828 Licochalcone A Licochalcone A is an estrogenic flavanoid extracted from licorice root, showing antimalarial, anticancer, antibacterial and antiviral activities. Phase 3.
E0225 Licochalcone B

Licochalcone B (Lico B), extracted from Glycyrrhiza uralensis Fisch, induces the cell cycle arrest and apoptosis in human hepatoma cell HepG2. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction.

S6899 Licochalcone D Licochalcone D (Lico D, LCD, LD), a flavonoid isolated from a Chinese medicinal plant Glycyrrhiza inflata, has antioxidant, anti-inflammatory and anti-cancer properties. Licochalcone D inhibit phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone D inhibits JAK2, EGFR and Met (c-Met) activities and induces ROS-dependent apoptosis. Licochalcone D also induces caspases activation and poly (ADP-ribose) polymerase (PARP) cleavage.
S2121 Licofelone (ML3000) Licofelone (ML3000, Compound 3e) is a dual inhibitor of COX and 5-lipoxygenase (5-LOX) with IC50 of 0.21 μM and 0.18 μM, respectively. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins. Licofelone is considered as a treatment for osteoarthritis.
E2547 Licoflavone A Licoflavone A is a flavonoid isolated from the roots of Glycyrrhiza uralensis, inhibits protein tyrosine phosphatase-1B (PTP1B) with an IC50 of 54.5 μM.
E2615 Licoflavone B Licoflavone B is a flavonoid isolated from Glycyrrhiza inflata, inhibits S. mansoni ATPase (IC50, 23.78 µM) and ADPase (IC50, 31.50 µM) activity. Anti-schistosomiasis activity.
E2568 Licoflavone C

Licoflavone C is a prenyl-flavone extracted from <i>Genista ephedroides</i>, reduces the genotoxicity of cancer drugs in human peripheral lymphocytes.

E2584 Licoflavonol

Licoflavonol, a minor flavone from the roots of <i>Glycyrrhiza uralensis</i>, is an inhibitor of the <b>Salmonella type III secretion system (T3SS) </b>.

S1357 Lidocaine Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
S4667 Lidocaine hydrochloride Lidocaine hydrochloride (Lidothesin, Lignocaine, Xyloneural) is an inhibitor of epidermal growth factor receptor (EGFR) and has antiproliferative effect on human tongue cancer cells. Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmia agent.
S9424 Liensinine diperchlorate Liensinine, a major isoquinoline alkaloid, inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. It is a novel autophagy/mitophagy inhibitor.
S7958 Lificiguat (YC-1) Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha).
S7926 Lifirafenib (BGB-283) Lifirafenib (BGB-283, Beigene-283) potently inhibits RAF family kinases and EGFR activities in biochemical assays with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant.
S3714 Lifitegrast Lifitegrast (SAR1118,SHP-606) is a novel small molecule integrin antagonist that inhibits a specific T cell-mediated inflammatory pathway involved in the pathogenesis of DED.
S8822 Ligandrol (LGD-4033) Ligandrol (LGD-4033, VK-5211) is a novel nonsteroidal, oral selective androgen receptor modulator with high affinity (Ki of ∼1 nM) and selectivity.
E3338 Lignum Dalbergiae odoriferae Extract
E3000 Ligusticum Sinense Extract Ligusticum Sinense Extract is extracted from Ligusticum sinense, a Chinese medicinal plant.
S9385 Ligustilide Ligustilide is the most abundant bioactive ingredient in Rhizoma Chuanxiong, a Chinese medicinal herb commonly used for the treatment of cardiovascular ailments. Solutions are best fresh-prepared.
S3775 Ligustrazine hydrochloride Ligustrazine hydrochloride (Tetramethylpyrazine, Tetrapyrazine) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.
S9096 ligustroflavone Ligustroflavone (Nuezhenoside), isolated from the leaves of Turpinia montana, shows high antioxidant capacity and is reported to be an AMPK activator.
E3042 Lily Bulbs Extract
S5895 LIN28 inhibitor LI71 LIN28 inhibitor LI71 is a potent and cell-permeable inhibitor of LIN28, which abolishes LIN28-mediated oligouridylation with IC50 of 7 μM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28's activity against let-7 in leukemia cells and embryonic stem cells.
P1109 Linaclotide Linaclotide is a potent and selective guanylate cyclase C (GC-C) agonist that elicits pharmacological effects locally in the gastrointestinal tract. 
S3031 Linagliptin (BI-1356) Linagliptin (BI-1356) is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM and exhibits a 10,000-fold higher selectivity for DPP-4 than for other dipeptidyl peptidases such as DPP-2, DPP-8, and DPP-9. Linagliptin activates glomerular autophagy in a model of type 2 diabetes. DPP4 mediates ferroptosis in TP53-deficient CRC cells.
S4957 Linalool Linalool (Phantol), a monoterpene compound commonly found as major component of essential oils of several aromatic species, is a competitive antagonist of NMDA receptors.
E0148 Linalyl Acetate

Linalyl Acetate (Bergamiol, Bergamol, Linalool acetate) is a naturally occurring phytochemical found in many flowers and spice plants. Linalyl Acetate is a potentially anti-inflammatory agent.

S9290 Linarin Linarin (Acaciin, Buddleoside, Acacetin-7-O-rutinoside), a natural flavonoid cpompound, has pharmacological effects, including anti-inflammatory, neuro-protective, cardioprotective and antioxidative effects.
S2479 Lincomycin HCl Lincomycin hydrochloride (Lincocin, NSC 70731) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.
S5295 Lincomycin Hydrochloride Monohydrate Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.
E3723 Lindera aggregata leaves Extract
E0011 Linderalactone Linderalactone inhibits human lung cancer growth by modulating the expression of apoptosis-related proteins (Bax and Bcl-2) with an IC50 of 15 µM in A-549 cells. Linderalactone induces G2/M cell cycle arrest and could also suppress the JAK/STAT signalling pathway. Linderalactone can be isolated from Radix linderae.
S3280 Linderene Linderene (Lindenenol) is a furanosesquiterpenoid isolated from Lindera pulcherrima with antibacterial and antioxidant activities.
S3529 Linerixibat Linerixibat (GSK 2330672, GSK 672), a highly potent, nonabsorbable inhibitor of apical sodium dependent bile acid transporter (ABST), also known as the ileal bile acid transporter (IBAT), is used to the treatment of cholestatic pruritus in primary biliary Cholangitis. The IC50 of human ASBT is 42 nM.
S1408 Linezolid (PNU-100766) Linezolid (PNU-100766) is a synthetic antibiotic used for the treatment of serious infections.
S1003 Linifanib (ABT-869) Linifanib (ABT-869, AL39324, RG3635) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, Flt-1/3 and PDGFRβ with IC50 of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3). Linifanib (ABT-869) induces autophagy and apoptosis. Phase 3.
S5821 Linoleic acid Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid used in the biosynthesis of arachidonic acid and found in the lipids of cell membranes.
S8629 Linrodostat (BMS-986205) Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.
S1091 Linsitinib (OSI-906) Linsitinib (OSI-906) is a selective inhibitor of IGF-1R with IC50 of 35 nM in cell-free assays; modestly potent to InsR with IC50 of 75 nM, and no activity towards Abl, ALK, BTK, EGFR, FGFR1/2, PKA etc. Phase 3.
S0753 Lintitript Lintitript (SR 27897) is a highly potent, selective, orally active, competitive and non-peptide antagonist of cholecystokinin (CCK1) receptor with EC50 of 6 nM and Ki of 0.2 nM. Lintitript displays > 33-fold selectivity more selective for CCK1 than CCK2 receptors with EC50 of 200 nM. Lintitript increases plasma concentration of leptin and food intake as well as plasma concentration of insulin.
S4217 Liothyronine Sodium Liothyronine Sodium(Cytomel) is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.
L9200 Lipid Metabolism Compound Library A unique collection of 410 lipid metabolism related compounds used for high throughput screening(HTS) and high content screening(HCS).
A5310 Lipoprotein lipase Rabbit Recombinant mAb Lipoprotein lipase Rabbit Recombinant mAb detects endogenous level of total Lipoprotein lipase.
S7699 Liproxstatin-1 Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.
E3436 Liquidambar formosana Extract
S3929 Liquiritigenin Liquiritigenin (4',7-Dihydroxyflavanone), the most active estrogenic compound from the root of Glycyrrhizae uralensis Fisch, selectively binds to ERβ with an IC50 value of 7.5 μM and activates multiple ER regulatory elements and native target genes with Erβ but not ERα.
S3930 Liquiritin Liquiritin (LIQ, Liquiritoside, Liquiritigenin-4'-O-glucoside) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.
S0964 Liquiritin apioside Liquiritin apioside is a main flavonoid component of licorice that possesses antitussive effects.
S8256 Liraglutide (NN2211) Liraglutide (Victoza, Liraglutida, Liraglutidum, NN2211) is a long-acting glucagon-like peptide-1(GLP-1) receptor agonist.
S8353 Lirametostat (CPI-1205) Lirametostat (CPI-1205) is an orally available selective inhibitor of the histone lysine methyltransferase EZH2 with IC50 values of 2 nM and 52 nM for EZH2 and EZH1 respectively. It has potential antineoplastic activity.
S1997 Liranaftate Liranaftate (M-732) is a squalene epoxidase inhibitor with anti-fungicidal activities.
S2076 Lisinopril dihydrate Lisinopril dihydrate(MK-521 dihydrate) is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.
E0620 LIT-001 trifluoroacetate

LIT-001 trifluoroacetate is the first nonpeptide oxytocin receptor agonist that improves social interaction in a mouse model of autism.

S3353 Lithium acetoacetate Lithium acetoacetate (LiAcAc, Acetoacetic acid lithium salt, Lithium 3-oxobutanoate) is an active endogenous metabolite that affects the growth of cells. Lithium acetoacetate can be used as an acetoacetate standard for the measurement of acetoacetate in biological samples.
S4933 Lithium carbonate Lithium carbonate (Li2CO3) is an inorganic compound that is valuable and effective agent in the treatment and prophylaxis of mood disorders, particularly bipolar disorder (BD). Lithium carbonate is able to alter D2 dopamine receptors response.
E0153 Lithium Chloride

Lithium Chloride (LiCl) inhibits the replication of type 1 and type 2 Herpes simplex virus at concentrations which permitted host cell replication. Lithium chloride also prevents glucocorticoid-induced osteonecrosis of femoral heads and strengthens mesenchymal stem cell activity in rats.

S4003 Lithocholic acid Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activates the vitamin D receptor, PXR and FXR.
S9073 Lithospermoside Lithospermoside (Griffonin), extracted from the roots of Lithospermum purpurocaeruleum and L.officinale (Borginaceae), and Thalictrum rugosum and T. dasycarpum (Ranunculaceae), has anti-oxidant, anti-tumor promoting activities.
E3890 Lithospermum Erythrorhizon Extract
S8517 Lixisenatide Lixisenatide (Lyxumia, Adlyxin, ZP10A peptide, AVE0010) is a once-daily short-acting glucagon-like peptide-1 (GLP-1) receptor agonist (GLP-1RA) with an IC50 of 1.4 nM for the human GLP-1 receptor in receptor binding studies.
S2815 Lixivaptan (VPA-985) Lixivaptan (VPA-985, CRTX 080, WAY VPA 985) is an oral, non-peptide, selective V2 receptor vasopressin antagonist with IC50s of 1.2 nM and 2.3 nM for human V2 receptor and rat V2 receptor, respectively.
E2027 LL-37(human) LL-37, human is a 37-residue, amphipathic, cathelicidin-derived peptide, which exhibits a broad spectrum of antimicrobial activity.
P1201 LL37 (Human cathelicidin) LL37 (Human cathelicidin, Ropocamptide) is a cathelicidin-related antimicrobial peptide with potent chemotactic and immunomodulatory properties.
S8883 LLY-283 LLY-283 is a novel and selective inhibitor of protein arginine methyltransferase 5 (PRMT5). LLY-283 inhibits PRMT5 enzymatic activity in vitro and in cells with IC50 of 22 nM and 25 nM, respectively. LLY-283 shows antitumor activity.
S8479 LLY-284 LLY-284 is the diastereomer of LLY-283, which is a potent and selective SAM-competitive chemical probe for PRMT5. LLY-284 is much less active than LLY-283 and can be used as a negative control for LLY-283.
S7575 LLY-507 LLY-507 is a cell-active, potent, and selective inhibitor of protein-lysine Methyltransferase SMYD2.
S8368 LM10 LM10 is a selective tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50 values of 0.62 and 2 μM for human and mouse TDO, respectively.
S9848 LM11A-31

LM11A-31 is a small molecule p75NTR Ligand that reverses cholinergic neurite dystrophy in alzheimer's diseasemousemodels with mid- to late-stage disease progression.

S0827 LM22A-4 LM22A-4 (LM 22A4) is a specific agonist of tyrosine kinase receptor B (TrkB) that reduces the development of tissue injury associated with spinal cord trauma.
S6760 LM22B-10 LM22B-10 is a small molecule TrkB/TrkC neurotrophin receptor co-activator, LM22B-10 selectively activates TrkB, TrkC, AKT and ERK in vivo and in vitro.
S0804 LML134 LML134 is an orally active and highly selective inverse agonist of Histamine 3 receptor (H3R) with Ki of 0.3 nM and 12 nM for hH3R cAMP and hH3R bdg, respectively. LML134 has the potential for excessive sleep disorders.
S0044 LMP744 LMP744 (MJ-III65, NSC706744) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.
E0635 LMPTP INHIBITOR 1 dihydrochloride LMPTP INHIBITOR 1 dihydrochloride is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC50 of 0.8 μM.
E1153 LMT-28 LMT-28 is a novel synthetic interleukin-6 (IL-6) inhibitor that functions through direct binding to gp130.
E3049 Lobeliae Chinensis Extract
S5844 Lobelin sulphate Lobelin sulphate (Lobeline sulfate, Bantron) is an alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent. It has a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
S3972 Lobeline hydrochloride Lobeline hydrochloride is an alkaloid that acts on nicotinic cholinergic receptors but is less potent than nicotine. It is also a VMAT2 ligand and an antagonist of μ-opioid receptors.
E2179 Lobetyol
E2092 Lobetyolinin Lobetyolin is a bioactive compound isolated from Codonopsis pilosula, which has anti-inflammatory, antioxidant and xanthine oxidase inhibitory activities.
S0321 LOC14 LOC14 is a potent inhibitor of protein disulfide isomerase (PDI) with EC50 of 500 nM and Kd of 62 nM, respectively.
E0617 Lodenafil Lodenafil (Hydroxyhomosildenafil) is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED).
S5674 Lodoxamide Tromethamine Lodoxamide Tromethamine (Alomide, Lodoxamidetromethamine) is the tromethamide salt form of lodoxamide, a synthetic mast cell stabilizing compound with anti-inflammatory activity.
S9191 Loganic acid Loganic acid (Loganate) is a naturally occurring iridoid monoterpeneglusoside involved in the biosynthesis of indole alkaloids in Vinca rosea.
S3835 Loganin Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. It is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.
S5491 Lomefloxacin Lomefloxacin(SC47111A) is a fluoroquinolone antibiotic used to treat bacterial infections.
S2539 Lomefloxacin HCl Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic.
S8056 Lomeguatrib Lomeguatrib (PaTrin-2) is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase with IC50 of 5 nM.
S4084 Lomerizine 2HCl Lomerizine dihydrochloride (KB-2796) is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine.
S1480 Lomibuvir (VX-222) Lomibuvir (VX-222, VCH-222) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L. Phase 2.
S7635 Lomitapide Lomitapide (AEGR-733, BMS-201038) is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.
S7633 Lomitapide Mesylate Lomitapide Mesylate(AEGR-733 Mesylate,BMS-2138 Mesylate) is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.
S1840 Lomustine Lomustine (NSC79037, Gleostine, CeeNU, CCNU) inhibits cancer cells by damaging the DNA and stops cells from dividing.
S2797 Lonafarnib (SCH66336) Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.
E3240 Longan Extract
S6578 Longdaysin Longdaysin is a Casein Kinase inhibitor with IC50 values of 8.8 μM, 5.6 μM, 52 μM and 29 μM for CKIδ, CKIα, ERK2 and CDK7.
E3360 Lonicera japonica Extract Lonicera japonica Extract (Japanese honeysuckle Extract), isolated from the leaves and flowers of Lonicera japonica (Japanese honeysuckle), possesses antipyretic, antibiotic, antioxidant, and anti-inflammatory activities.
E3584 Lonicera japonica vine Extract
E3619 Lonicerae Flos Extract Lonicerae Flos Extract is extracted from Lonicerae flos, the flower bud of Lonicera macranthoides Hand.-Mazz., Lonicera hypoglauca Miq., Lonicera confusa DC., or Lonicera fulvotomentosa Hsu et S. C. Cheng. Lonicerae flos is a traditional Chinese medicine used in the treatment of inflammatory and infectious diseases. Lonicerae flos extract increases survival rates of cecal ligation and puncture (CLP)-induced septic rats.
E0904 Lonicerin

Lonicerin targets EZH2 to alleviate ulcerative colitis by autophagy-mediated NLRP3 inflammasome inactivation.

S2610 Lonidamine (AF-1890) Lonidamine (AF 1890, Diclondazolic Acid, DICA) is an orally administered small molecule hexokinase inactivator.
S2480 Loperamide HCl Loperamide HCl (ADL 2-1294) is a selective μ-opioid receptor agonist opioid with Ki of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.
E3138 Lophatheri Herba Extract
S1380 Lopinavir (ABT-378) Lopinavir (ABT-378) is a potent HIV protease inhibitor with Ki of 1.3 pM in a cell-free assay.
E3533 Loquat leaf Extract
S1358 Loratadine (SCH29851) Loratadine (SCH29851) is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
S0347 Loreclezole Loreclezole is an antiepileptic compound that selectively modulates GABAA receptor. Loreclezole is a positive allosteric modulator of β2 or β3-subunit containing receptors.
S0453 Lorediplon Lorediplon, a novel non-benzodiazepine hypnotic drug, is a modulator of GABAA receptor. Lorediplon is differentially active at the alpha1-subunit and associated with promoting sleep.
S7536 Lorlatinib (PF-6463922) Lorlatinib (PF-6463922) is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively. PF-06463922 induces apoptosis. Phase 1.
S2047 Lornoxicam Lornoxicam (Chlortenoxicam) is a non-steroidal COX-1/COX-2 inhibitor, used as an anti-inflammatory drug to treat pain, osteoarthritis, and rheumatoid arthritis.
S5067 Losartan Losartan(DuP-753) is a selective, orally administered, nonpeptide blocker of angiotensin II type 1 (AT1) receptor used to treat high blood pressure, diabetic kidney disease, heart failure, and left ventricular enlargement.
S5980 Losartan Carboxylic Acid (EXP-3174) Losartan Carboxylic Acid (E-3174, EXP-3174), an active carboxylic acid metabolite of Losartan, is a non-peptide angiotensin II (AT1) receptor antagonist. Losartan Carboxylic Acid inhibits the specific binding of [125I]-angiotensin II to VSMC with IC50 of 1.1 nM.
S1359 Losartan Potassium (DuP 753) Losartan Potassium (DuP 753, MK 954) is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
S7215 Losmapimod (GW856553X) Losmapimod (GW856553X, GW856553, GSK-AHAB) is a selective, potent, and orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. P38 MAPKs are involved in cell differentiation, apoptosis and autophagy. Phase 3.
S0190 Lotamilast (RVT-501) Lotamilast (RVT-501, E6005) is a selective phosphodiesterase 4 (PDE4) inhibitor with an IC50 of 2.8 nM.
S1669 Loteprednol etabonate Loteprednol etabonate is a potent glucocorticoid receptor agonist, used in treatment of inflammation of the eye due to allergies.
E3416 Lotus seed Extract
E2544 Lotusine Lotusine, a pure alkaloid extracted from the green seed embryo of Nelumbo nucifera Gaertn., shows effect on the action potentials in myocardium and slow inward current in cardiac Purkinje fibers.
S3241 Loureirin A Loureirin A is a flavonoid extracted from the red resin of the herbs of Dracaena cochinchinensis, which is known as Dragon's Blood. Loureirin A inhibits platelet activation by an impairment of PI3K/Akt signaling. Loureirin A inhibits Akt phosphorylation.
S3242 Loureirin B Loureirin B (LB, LrB), a flavonoid extracted from Dracaena cochinchinensis, is an inhibitor of PAI-1 with IC50 of 26.10 μM. Loureirin B downregulates p-ERK and p-JNK in TGF-β1-stimulated fibroblasts. Loureirin B promotes insulin secretion mainly through increasing Pdx-1, MafA, intracellular ATP level, inhibiting the KATP current, influx of Ca2+ to the intracellular.
E2006 Loureirin C

Loureirin C  is a natural component with anti-bacterial, anti-inflammatory and anti-tumor activities.

E2105 Loureirin D

Loureirin D is a dihydrochalcone isolated from dragon’s blood.

S2061 Lovastatin (MK-803) Lovastatin (MK-803, Mevinolin,Mevacor) is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, used for lowering cholesterol (hypolipidemic agent). Lovastatin triggers autophagy.
E0145 LOX-IN-3 Dihydrochloride

LOX-IN-3 Dihydrochloride is an orally active and selective lysyl oxidase (LOX) inhibitor.

S5197 Loxapine Loxapine (Adasuve), a typical neuroleptic, is a drug with D2/D3 receptor antagonist activity and a higher affinity for D3 than D2. Loxapine displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors.
S4086 Loxapine Succinate Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.
S0247 Loxiglumide Loxiglumide (CR-1505) is an antagonist of cholecystokinin (CCK-1) receptor.
S7392 Loxistatin Acid (E-64C) Loxistatin Acid (E-64C, NSC 694279, EP 475), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor. The cysteine protease cathepsin L is required for SARS-CoV-2 viral entry.
S4682 Loxoprofen Loxoprofen (Koloxo, Loxoprofene, Loxoprofeno) is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group.
S5412 Loxoprofen Sodium Loxoprofen sodium is a non-steroidal anti-inflammatory drug.
E0108 LQZ-7I LQZ-7I is a novel selectively inhibitor of survivin dimerization with IC50s of 4.8 µM and 3.1 µM in prostate cancer cell lines PC-3 and C4-2, respectively. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors.
A5229 LRP1 Rabbit Recombinant mAb LRP1 Rabbit Recombinant mAb dectectes endogenous level of total LRP1.
A5479 LSD2/AOF1 Rabbit Recombinant mAb LSD2/AOF1 Rabbit Recombinant mAb detects endogenous level of total LSD2/AOF1.
P1164 LSKL, Inhibitor of Thrombospondin (TSP-1) LSKL, Inhibitor of Thrombospondin (TSP-1), a small molecular peptide and competitive antagonist for transforming growth factor-β1 (TGF-β1), protects against subarachnoid fibrosis and hydrocephalus after subarachnoid hemorrhage (SAH).
S6381 LSP-249 LSP-249 (example 35) is a plasma kallikrein inhibitor under the study for angioedema with EC50 <100 nM in cell.
A5326 LSP1 Rabbit Recombinant mAb LSP1 Rabbit Recombinant mAb detects endogenous level of total LSP1.
S1024 LTI-291 LTI-291 is the first small-molecule activator of Glucocerebrosidase(GCase) for the treatment of parkinson's disease.
S0223 Lu AF21934 Lu AF21934 is a selective, brain-penetrant and positive allosteric modulator of mGlu4 receptor with IC50 of 500 nM for human mGlu4.
S0017 Lu-135252 Lu-135252 (Darusentan,HMR-4005) is a selective endothelin A receptor (ET-A receptor) antagonist indicated for the oral treatment of resistant hypertension.
S1675 Lubiprostone Lubiprostone (RU 0211) is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation.
S6471 Lucanthone Lucanthone is a novel autophagic inhibitor and also an orally available thioxanthone-based DNA intercalator and inhibitor of the DNA repair enzyme apurinic-apyrimidinic endonuclease 1.
E3692 lucid asparagus Extract
E2001 Lucidenic acid E Lucidenic acid E is a terpenoid found in Ganoderma lucidum.
S6824 Lucigenin Lucigenin (NSC-151912, L-6868) is a fluoerscent probe that exhibits a bluish-green fluorescence in the presence of endogenously generated superoxide anion radicals and chloride in cells.
S7647 Lucitanib (E3810) hydrochloride Lucitanib (E-3810, AL3810) hydrochloride is a dual inhibitor of Vascular endothelial growth factor receptor (VEGFR) and Fibroblast growth factor receptor (FGFR). Lucitanib hydrochloride (E-3810, AL3810) potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 with IC50 of 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively.
E0542 Lucyoside B

Lucyoside B inhibits the production of inflammatory mediators via both NF-κB and activator protein-1 pathways in activated macrophages.

E3664 Luffa Cylindrica Stem Extract
S9858 Lufotrelvir (PF-07304814)

PF-07304814 is a phosphate prodrug of PF-00835231 that binds and inhibits SARS-CoV-2 3CLpro activity with a Ki of 174 nM.

S4258 Luliconazole Luliconazole(NND 502) is a broad-spectrum antifungal drug.
S1565 Lumacaftor (VX-809) Lumacaftor (VX-809, VRT 826809) acts to correct CFTR mutations common in cystic fibrosis by increasing mutant CFTR (F508del-CFTR) maturation,EC50 of 0.1 μM in fisher rat thyroid cells. Phase 3.
S3746 Lumefantrine Lumefantrine (benflumetol) is an antimalarial agent used to treat acute uncomplicated malaria.
S1069 Luminespib (NVP-AUY922) Luminespib (AUY-922, NVP-AUY922, VER-52296) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Luminespib (AUY-922, NVP-AUY922) effectively downregulates and destabilizes the IGF-1Rβ protein and results in growth inhibition, autophagy and apoptosis. Phase 2.
S6819 Luminol Luminol (Diogenes reagent, 3-Aminophthalhydrazide) is a versatile chemical exhibiting chemiluminescence with a blue glow, when mixed with an appropriate oxidizing agent. Luminol is uesed in forensic investigations to detect trace amounts of blood at crime scenes and in biological researches to detect copper, iron, and cyanides, as well as specific proteins by western blot. Luminol recently displayes promising applications for the treatment of cancer in deep tissues.
S2903 Lumiracoxib Lumiracoxib (COX-189) is a novel, selective COX-2 inhibitor with Ki of 0.06 μM. It also inhibits COX1 with Ki of 3 μM.
E0020 Lupenone Lupenone (Lup-20(29)-en-3-one, lupeone) is an isolated compound exhibiting anti-oxidative, anti-inflammation, and anti-diabetic activities. Lupenone can protect SH-SY5y cells against METH-induced neuronal apoptosis through the PI3K/Akt pathway.
S3614 Lupeol Lupeol (Clerodol, Monogynol B, Fagarasterol, Farganasterol) is a significant lupane-type triterpene represented in the plant, fungi and animal kingdoms with anticancer, antiprotozoal, chemopreventive and anti-inflammatory properties.
E2567 Lupiwighteone

Lupiwighteone (8-prenylgenistein), an isoflavone present widely in wild-growing plants with antioxidant, antimicrobial and anticancer effects, induces caspase-dependent and -independent apoptosis on human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway.

S5714 lurasidone Lurasidone (SM-13496) is a second-generation antipsychotic agent that exhibits full antagonism at dopamine D2 and serotonin 5-HT2A receptors with binding affinities Ki = 1 nM and Ki = 0.5 nM, respectively. It also has high affinity for serotonin 5-HT7 receptors (Ki = 0.5 nM), partial agonist activity at 5-HT1A receptors (Ki = 6.4 nM) and lacks affinity for histamine H1 and muscarinic M1 receptors.
S3044 Lurasidone HCl Lurasidone (SM-13496) is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively.
S9603 Lurbinectedin (PM01183) Lurbinectedin (PM01183, PM-1183, LY-01017, Tryptamicidin, Zepsyre, ZEPZELCA), a DNA minor groove covalent binder with potent in vitro and in vivo anti-tumour activity. Lurbinectedin inhibits RMG1 and RMG2 cell growth with IC50 of 1.25 nM and 1.16 nM, respectively.
E2183 Lusianthridin
S6988 Lusutrombopag Lusutrombopag (Mulpleta, S-888711) is an orally bioavailable thrombopoietin (TPO) receptor agonist being developed for chronic liver disease (CLD).
S0800 LUT014 LUT014 is an inhibitor of B-Raf with IC50 of 11.7 nM, and reduces dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.
S2320 Luteolin Luteolin (Luteoline, Luteolol, Digitoflavone) is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM, respectively. Phase 2.
E2463 Luteolin 3'-O-beta-D-glucuronide

Luteolin 3'-O-beta-D-glucuronide is a luteolin glucosiduronic acid consisting of luteolin having a beta-D-glucosiduronic acid residue attached at the 3'-position.

E2732 Luteolin 4'-O-glucoside

Luteolin-4'-glucoside is a natural product found in <i>Lathyrus pratensis</i>.

E0131 Luteolin-7-O-glucuronide

Luteolin-7-O-glucuronide (Luteolin 7-glucuronide) is a flavone glycoside found in plants. Luteolin-7-O-glucuronide possesses anti-microbial, antioxidant, anti-mutagenic, anti-genotoxic, anti-inflammatory, and anti-arthritic activities.

E2485 Luteolinidin chloride

Luteolinidin chloride, a natural deoxyanthocyanidin, isolated from mosses and ferns, is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.

S9018 Luteoloside Luteoloside (Cynaroside, Luteolin 7-β-D-Glucopyranoside) is a member of the flavonoids family that exhibits several bioactivities including anti-microbial and anti-cancer activities. It is an inhibitor of 3C Protease of Enterovirus 71 with an IC50 value of 0.36 mM.
S3584 Luzindole Luzindole (N-0774, N-acetyl-2-benzyltryptamine) is a selective melatonin receptor antagonist with Kis of 179 nM for MT1 and 7.3 nM for MT2, respectively.
S0222 Lvguidingan Lvguidingan (Anticonvulsant 7903, 3,4-dichlorophenyl propenylisobutylamide) is an anticonvulsant/antiepileptic agent. Lvguidingan (Anticonvulsant 7903) is found to be able to increase the concentration of 5-HT and 5-HIAA in mice brain.
S2978 LVN84663

LVN84663 is a useful reagent for determination of blood coagulating protease.

S8441 LW 6 LW 6 (CAY10585, AC1-001) is a hypoxia-inducible factor 1(HIF) inhibitor which potently inhibits HIF-1α accumulation by degrading HIF-1α without affecting the HIF-1a mRNA levels during hypoxia. LW6 inhibits HIF and MDH2 expression with IC50 values of 4.4 and 6.3 μM, respectively.
S6503 LX2343 LX2343 is a multi-target agent that exhibits a high capability for ameliorating multi-abnormalities of AD pathogenesis. It is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM.
A5313 LXR alpha Rabbit Recombinant mAb LXR alpha Rabbit Recombinant mAb detects endogenous level of total LXR alpha.
S8390 LXR-623 (WAY-252623) LXR-623 (WAY-252623) is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier.
S8772 LY 3200882 LY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.
S5276 LY 344864 racemate LY 344864 is a selective receptor agonist of the recently cloned 5-HT1F receptor with Ki of 6 nM.
S8052 LY-2183240 LY-2183240 is a potent, covalent inhibitor of the EC-degrading enzyme fatty acid amide hydrolase (FAAH). LY-2183240 disrupts the cellular uptake of the lipid endocannabinoid (EC) anandamide and promote analgesia in vivo. LY-2183240 is also an inhibitor of monoacylgylcerol lipase (MGL).
S0429 LY-2940094 LY-2940094 is a potent, selective and orally available antagonist of nociceptin receptor (NOP receptor) with Ki of 0.105 nM and Kb of 0.166 nM. LY-2940094 reduces ethanol self-administration in animal models.
S8919 LY-3381916 LY-3381916 (IDO1-IN-5) is a brain penetrated, potent and selective Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor. LY-3381916 exhibits anti-tumor activity.
S9867 LY-3475070 LY-3475070 is a potent, selective and orally bioavailable inhibitor of the ectoenzyme CD73 (cluster of differentiation 73, 5'-ecto-nucleotidase, 5'-NT, ecto-5'-nucleotidase).
S7063 LY2090314 LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM; may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 is highly selective towards GSK3 as demonstrated by its fold selectivity relative to a large panel of kinases.
S2704 LY2109761 LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM in a cell-free assay, respectively; shown to negatively affect the phosphorylation of Smad2. LY2109761 blocks autophagy and induces apoptosis.
S0055 LY2444296 (FP3FBZ) LY2444296 (FP3FBZ) is an orally bioavailable, high-affinity and selective short-acting kappa opioid receptor (KOPR) antagonist with Ki of ∼1 nM. LY2444296 (FP3FBZ) exhibits anti-anxiety like effects.
S8505 LY2510924 LY2510924 is a potent and selective CXCR4 antagonist that specifically blocks SDF-1 binding to CXCR4 with IC50 value of 0.079 nmol/L and inhibits SDF-1-induced GTP binding with Kb value of 0.38 nmol/L.
S2959 LY255283 LY255283 is an antagonist of leukotriene B4 (LTB4) receptor (BLT2) that displaces [3H]LTB4 from its binding site on lung membranes with pKi of 7.0.
S0403 LY2562175 LY2562175 is a potent and selective agonist of FXR. LY2562175 promotes transcriptional activation of human FXR in a cell-based cotransfection assay with EC50 of 193 nM.
S7698 LY2584702 LY2584702 is a selective, ATP-competitive p70S6K inhibitor with IC50 of 4 nM. Phase 1.
S7704 LY2584702 Tosylate LY2584702 Tosylate is a selective, ATP-competitive p70S6K inhibitor with IC50 of 4 nM. Phase 1.
S2155 LY2608204 LY2608204 activates glucokinase (GK) with EC50 of 42 nM. Phase 2.
S0046 LY2795050 LY2795050 is a novel selective κ-opioid Receptor (KOR) antagonist with IC50 of 0.72 nM and has the potential as a PET tracer to image KOR in vivo.
S1528 LY2811376 LY2811376 is the first orally available non-peptidic β-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM, that act to decrease Aβ secretion with EC50 of 300 nM, demonstrated to have 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including cathepsin D, pepsin, or renin. Phase 1.
S0427 LY2828360 LY2828360 is a slowly acting but efficacious agonist of G protein-biased cannabinoid (CB2). LY2828360 inhibits cAMP accumulation and activates ERK1/2 signaling.
S7057 LY2874455 LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM, 2.6 nM, 6.4 nM, and 6 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively, and also inhibits VEGFR2 activity with IC50 of 7 nM. Phase 1.
S2156 LY2886721 LY2886721 is a BACE inhibitor used for the treatment of Alzheimer's Disease. Phase 1/2.
S1105 LY294002 LY294002 (SF 1101, NSC 697286) is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation. It not only binds to class I PI3Ks and other PI3K-related kinases, but also to novel targets seemingly unrelated to the PI3K family. LY294002 also inhibits CK2 with IC50 of 98 nM. LY294002 is a non-specific DNA-PKcs inhibitor and activates autophagy and apoptosis.
S7842 LY3009120 LY03009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. LY03009120 induces autophagy. Phase 1.
S9650 LY3143921 hydrate LY3143921 hydrate is an orally administered ATP-competitive CDC7 inhibitor.
S8782 LY3295668 LY3295668 (AK-01) is a potent, orally active and specific inhibitor of Aurora A kinase with Ki of 0.8 nM and 1038 nM for AURKA and AURKB, respectively.
S0299 LY334370 LY334370 is a selective agonist of 5-HT1F receptor with Ki of 1.6 nM.
S6884 LY3405105 LY3405105 is an orally active CDK7 inhibitor with an IC50 of 92.8 nM. LY3405105 shows potential antineoplastic activity.
S2805 LY364947 LY364947 (HTS 466284) is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM in a cell-free assay, shows 7-fold selectivity over TGFβR-II.
S2714 LY411575 LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch cleavage with IC50 of 0.39 nM in APP or NΔE expressing HEK293 cells. LY411575 induces apoptosis.
S0748 LY88074 LY88074, a Raloxifene analog lacking the basic side chain, is a selective modulator of estrogen receptor. LY88074 reduces fracture risk at least in part by improving the mechanical properties of bone in a cell- and estrogen receptor-independent manner.
E3229 Lycii Fructus Extract
S3286 Lycobetaine

Lycobetaine is a quaternary phenanthridinium alkaloid from Lycoris radiata of the Amaryllidaceae family, with significant cytotoxic activity against Lewis lung carcinoma.

S3943 Lycopene Lycopene (ψ,ψ-Carotene) is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. It is a natural antioxidant.
E3738 Lycopersicon esculentum Miller Extract
E3651 Lycopodiastrum casuarinoides Extract
E3629 Lycopodii Herba Extract Lycopodii Herba Extract is extracted from Lycopodii Herba, the dried whole plant of Lycopodium japonicum Thunb. (Lycopodiaceae). Lycopodii Herba possesses anti-inflammation activity, antioxidative activity, and antitumor activity; and has been traditionally used for the prevention and treatment of various diseases such as rheumatoid arthritis, contusion, quadriplegia, dysmenorrhea.
E3859 Lycopus Extract
S3903 Lycorine Lycorine (Galanthidine, Amarylline, Narcissine, Licorine, Belamarine) is a toxic crystalline alkaloid found in various Amaryllidaceae species that weakly inhibits acetylcholinesterase (AChE) and ascorbic acid biosynthesis.
S3800 Lycorine hydrochloride Lycorine (Galanthidine, Amarylline, Narcissine, Licorine), a natural alkaloid extracted from the Amaryllidaceae plant family, has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. It is an HCV inhibitor with strong activity.
E3246 Lygodii Spora Extract
S8597 LYN-1604 LYN-1604 is a potential ULK1 agonist with IC50 of 1.66 μM against MDA-MB-231 cells and it binds to wild-type ULK1 with a binding affinity in the nanomole range (Kd=291.4 nM). The ULK1 (Y89A) mutant protein caused a sharp decrease in binding affinity with lower response and Kd than wild-type ULK1, ULK1 (K50A) and ULK1 (L53A) mutants.
S4883 Lynestrenol Lynestrenol (Ethinylestrenol) is a synthetic progestational hormone, an agonist of the progesterone receptor and has weak androgenic and estrogenic activity.
S0492 LYS-006 LYS-006 is a potent inhibitor of Leukotriene A4 hydrolase (LTA4H). LYS-006 can be used for the treatment of Hidradenitis Suppurativa.
E3357 Lysimachia christinae Hance extract
E3638 Lysinotus pauciflorus Extract
A5450 LYVE1 Rabbit Recombinant mAb LYVE1 Rabbit Recombinant mAb detects endogenous level of total LYVE1.
P1117 [Leu5]Enkephalin [Leu5]Enkephalin a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
S3887 α-L-Rhamnose monohydrate α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate) is used as a starting material for the production of furanones. It is an important material involved in the reaction of flavors developed during the preparation of various foods like bread, grilled meats, etc.
E2391 α-Linolenic acid α-Linolenic acid, an essential fatty acid isolated from seed oils, affects the process of thrombotic through the modulation of PI3K/Akt signaling, and possesses the anti-arrhythmic properties.
S5743 γ-Linolenic acid γ-Linolenic Acid (18:3, n-6), the Δ6-desaturase product of linolenic acid, is an unsaturated fatty acid found primarily in vegetable oils.