Ubiquitination Compound Library

Catalog No.L6000

A unique collection of 213 small molecules for Ubiquitination related research.

96 well plates

Customize Your Library:

Cited by 313 Publications

Description & Advantages

•A unique collection of 213 small molecules for for high throughput screening (HTS) and high content screening (HCS)
 
•Covers enzymes and other related factors of the ubiquitination system: Proteasome,DUB,E3 Ligase,E1 Activating,E2 conjugating,SUMO,etc,and ubiquitination related signaling pathway:mTOR,NF-kB,Wnt/beta-catenin,Hippo-YAP
 
•Structurally diverse, medicinally active, and cell permeable
 
•Rich documentation with structure, IC50, and customer reviews
 
•NMR and HPLC validated to ensure high purity

Product Details

Formulation 206 compounds pre-dissolved in 10mM DMSO and 7 compounds pre-dissolved in 2mM DMSO
Container 96 Deep Well Plate Sealed With Aluminum Foil
Stability 12 months -20°C in DMSO
24 months -80°C in DMSO
Shipping Blue ice or dry ice

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

    Nature.2019;574(7777):268-272

  • Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

    Nat Commun. 2019 16;10(1):2197

  • Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

    Cell Res. 2019;29(9):739-753

  • Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

    Mov Disord. 2019;34(3):323-334

  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

    Blood. 2019 17;134(16):1323-1336

  • Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

    Cancer Immunol Res.2017;5(9):790-803

Ubiquitination Compound Library Composition

HTS Facility Partners

  • Collaborating with Seleck: Yale University | Yale Center for Molecular Discovery
  • Collaborating with Seleck: Carbone Cancer Center | University of Wisconsin-Madison
  • Collaborating with Seleck: University of Colorado Denver | CU Denver
  • Collaborating with Seleck: Leibniz-Forschungsinstitut für Molekulare Pharmakologie: Leibniz-FMP
  • Collaborating with Seleck: UCSF_University of California San Francisco
  • Collaborating with Seleck: KU | High Throughput Screening Laboratory
  • Collaborating with Seleck: CIBIO
  • Collaborating with Seleck: Perelman school of medicine | University of Pennsylvania