Ubiquitination Compound Library

Catalog No.L6000

A unique collection of 198 small molecules for Ubiquitination related research.

96 well box

Customize Your Library:

Cited by 254 Publications

Description & Advantages
•A unique collection of 198 small molecules for for high throughput screening (HTS) and high content screening (HCS)
 
•Covers enzymes and other related factors of the ubiquitination system: Proteasome,DUB,E3 Ligase,E1 Activating,E2 conjugating,SUMO,etc,and ubiquitination related signaling pathway:mTOR,NF-kB,Wnt/beta-catenin,Hippo-YAP
 
•Structurally diverse, medicinally active, and cell permeable
 
•Rich documentation with structure, IC50, and customer reviews
 
•NMR and HPLC validated to ensure high purity
Product Details
Formulation 192 compounds pre-dissolved in 10mM DMSO and 6 compounds pre-dissolved in 2mM DMSO
Container 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability 12 months -20°C in DMSO
24 months -80°C in DMSO
Shipping Blue ice or dry ice
Case Studies using Selleck Compound Libraries
  • Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

    Nature.2019;574(7777):268-272

  • Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

    Nat Commun. 2019 16;10(1):2197

  • Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

    Cell Res. 2019;29(9):739-753

  • Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

    Mov Disord. 2019;34(3):323-334

  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

    Blood. 2019 17;134(16):1323-1336

  • Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

    Cancer Immunol Res.2017;5(9):790-803

Ubiquitination Compound Library Composition
HTS Facility Partners