PI3K/Akt Inhibitor Library

Catalog No.L2800

Offered in 96 or 384 well plate format

A unique collection of 173 small molecule inhibitors used for PI3K/Akt/mTOR pathway research.

Size

Price

Pre-dissolved In DMSO or Water
100uL/well (2mM or 10mM solution)	USD 5267
2x100uL/well (2mM or 10mM solution)	USD 7932

Selleck USA Tel: (832) 582-8158 [email protected]

You Could Select:

Specific Compounds Quantities Plate Map Dry/solid or DMSO solution

Customize Library

PI3K/Akt Inhibitor Library Contents

Download the PI3K/Akt Inhibitor Library - XLSX

Download the PI3K/Akt Inhibitor Library - SDF

Cited by 40 Publications

Nat Med,2017,23(4):405-408

PubMed: 28388612 ( click the link to review the publication )

Nat Med,2014,20(8):954-60

PubMed: 24997607 ( click the link to review the publication )

Genome Biol,2019,20(1):253

PubMed: 31771620 ( click the link to review the publication )

Sci Adv,2019,5(6):eaav9784

PubMed: 31249867 ( click the link to review the publication )

Neuropsychopharmacology,2019,10.1038/s41386-018-0266-7

PubMed: 30518933 ( click the link to review the publication )

Breast Cancer Res,2019,21(1):37

PubMed: 30845991 ( click the link to review the publication )

Neurobiol Aging,2019,76:24-34

PubMed: 30640040 ( click the link to review the publication )

Cancer Gene Ther,2019,10.1038/s41417-019-0127-5

PubMed: 31383953 ( click the link to review the publication )

Stem Cells Int,2019,2019:3435901

PubMed: 31871467 ( click the link to review the publication )

Cancer Manag Res,2019,11:8391-8405

PubMed: 31571995 ( click the link to review the publication )

Breast Cancer Res Treat,2019,10.1007/s10549-019-05504-5

PubMed: 31784862 ( click the link to review the publication )

Acta Pharmacol Sin,2019,10.1038/s41401-019-0246-4

PubMed: 31197246 ( click the link to review the publication )

Cell Signal,2019,67:109508

PubMed: 31866490 ( click the link to review the publication )

Virology,2019,541:41-51

PubMed: 31826845 ( click the link to review the publication )

Bioengineered,2019,10(1):98-107

PubMed: 31023186 ( click the link to review the publication )

Kaohsiung J Med Sci,2019,10.1002/kjm2.12051

PubMed: 30896891 ( click the link to review the publication )

Cell Rep,2018,22(5):1185-1199

PubMed: 29386107 ( click the link to review the publication )

Cancer Sci,2018,109(4):1220-1229

PubMed: 29453896 ( click the link to review the publication )

Sci Rep,2018,8(1):13106

PubMed: 30166612 ( click the link to review the publication )

J Cell Physiol,2018,233(1):422-433

PubMed: 28294327 ( click the link to review the publication )

J Cell Biochem,2018,119(1):300-313

PubMed: 28569433 ( click the link to review the publication )

Oncotarget,2018,9(57):31018-31031

PubMed: 30123424 ( click the link to review the publication )

Anal Chem,2017,89(12):6678-6685

PubMed: 28520400 ( click the link to review the publication )

Antimicrob Agents Chemother,2017,e01674-17

PubMed: 29061736 ( click the link to review the publication )
Pharmacol Res,2016,113(Pt A):216-227

PubMed: 27543462 ( click the link to review the publication )

PLoS One,2016,11(2):e0149848

PubMed: 26919709 ( click the link to review the publication )

Sensors (Basel),2016,16(3)

PubMed: 26999137 ( click the link to review the publication )

Clin Cancer Res,2015,21(5):1172-82

PubMed: 25549722 ( click the link to review the publication )

Biosens Bioelectron,2015,68:699-704

PubMed: 25668591 ( click the link to review the publication )

Mol Cancer Ther,2015,14(5):1213-23

PubMed: 25777964 ( click the link to review the publication )

Cell Cycle,2015,14(1):109-22

PubMed: 25602521 ( click the link to review the publication )

PLoS One,2015,10(11):e0142655

PubMed: 26569102 ( click the link to review the publication )

Oncotarget,2015,6(3):1531-43

PubMed: 25605238 ( click the link to review the publication )

Head Neck,2015,37(12):1722-32

PubMed: 24986420 ( click the link to review the publication )

Mol Cancer Res,2014,12(5):703-13

PubMed: 24554781 ( click the link to review the publication )

Oncotarget,2014,5(15):6512-25

PubMed: 25156567 ( click the link to review the publication )

Curr Protoc Chem Biol,2014,4:177-191

PubMed: 26705509 ( click the link to review the publication )

Description & Advantages

• A unique collection of 173 small molecule inhibitors used for PI3K/Akt/mTOR pathway research

• Targets PI3K, mTOR, Akt, GSK, ATM/ATR, etc

• A valuable tool for researching the survival, proliferation, and apoptosis of cells

• Structurally diverse, medicinally active, and cell permeable

• Rich documentation with structure and customer reviews

• NMR and HPLC validated to ensure high purity

Product Details

Formulation:	156 compounds pre-dissolved in 10mM DMSO, 5 compounds pre-dissolved in 10mM water and 12 compounds pre-dissolved in 2mM DMSO
Container:	96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability:	12 months -20°C in DMSO
Stability:	24 months -80°C in DMSO
Shipping:	Blue ice or dry ice
Packaging:	Inert gas

PI3K/Akt Inhibitor Library Composition

HTS Facility Partners

See Other Libraries

FDA-approved Drug Library

A unique collection of 2682 approved drugs for high throughput screening (HTS) and high content screening (HCS).
Drug Repurposing Library

A unique collection of 2826 drugs that are marketed around the world or have passed clinical phase 1 and can be used for high throughput screening (HTS) and high content screening (HCS).
Preclinical/Clinical Compound Library

A unique collection of 2564 preclinical and clinical compounds for high throughput screening (HTS) and high content screening (HCS).
Bioactive Compound Library-I

A unique collection of 6911 bioactive compounds for high throughput screening (HTS) and high content screening (HCS).
Bioactive Compound Library-Ⅱ

A unique collection of 5309 bioactive compounds for high throughput screening (HTS) and high content screening (HCS).
Kinase Inhibitor Library

A unique collection of 1255 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).
Express-Pick Library

A unique collection of 4208 chemical compounds featured different core structures and structural diversities respectively for high throughput screening (HTS) and high content screening (HCS).
Natural Product Library

A unique collection of 2054 natural products for high throughput screening (HTS) and high content screening (HCS).
Human Endogenous Metabolite Compound Library

525 small collections of human endogenous metabolites, involving multiple metabolic pathways, which can be used for high-throughput screening, opening up new ways for humans to treat various diseases such as tumors.
Angiogenesis Related compound Library

A unique collection of 113 small molecules used for angiogenesis research targeting Bcr-Abl,BTK,HIF,VEGFR,FGFR,FAK,etc.
Anti-Aging Compound Library

A unique collection of 1504 anti-aging compounds used for aging related research.
Anti-alzheimer Disease Compound Library

A unique collection of 486 small molecules for exploring the mechanism of Alzheimer's disease.
Antibiotics compound Library

A unique collection of 308 antibiotics used for anti- research in order to identify drug target and open up new mechanism and ways to treat human disease.
Anti-cancer Compound Library

A unique collection of 2279 anti-cancer compounds for multiple cancers: Breast Cancer, Leukemia, Lung Cancer, Lymphoma, etc.
Anti-cancer Compound Library (Verified by Broad Institute)

A unique collection of 923 compounds with anticancer activity which has been verified by broad institute,half of the compounds are non-oncology drugs.
Anti-cancer Metabolism Compound Library

A unique collection of 195 small molecules for cancer metabolism research.
Anti-diabetic Compound Library

A unique collection of 152 small molecules for exploring the development of diabetes.
Anti-infection Compound Library

A unique collection of 930 anti-infection compounds with biological activity of antibacterial,antifungal,antiviral,etc.
Antioxidant Compound Library

A unique collection of 429 compounds used for exploring the relationship between anti-oxidation and some diseases such as aging,cancer,alzheimer's disease,parkinson's disease,diabetes,etc.
Antiviral Compound Library

A unique collection of 348 antiviral compounds used for exploring novel antiviral drug.
Apoptosis Compound Library

A unique collection of 693 small molecules used for apoptosis research targeting Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survivin, etc.
Autophagy Compound Library

A unique collection of 822 small molecules with autophagy-inducing or autophagy-inhibiting activity.
Cambridge Cancer Compound Library

A unique collection of 247 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS).
Cell Cycle compound library

A unique collection of 120 small molecule compounds used for cell cycle and related diseases research.
CNS-Penetrant Compound Library

A unique collection of 307 CNS-Penetrant compounds with biological activity for neurologic research.
Covalent Inhibitor Library

A unique collection of 81 covalent Inhibitors for high throughput screening (HTS) and high content screening (HCS).
Cytoskeletal Signaling Pathway Compound Library

A unique collection of 185 compounds used for research in cytoskeleton and cytoskeletal interactions.
DNA Damage/DNA Repair compound Library

A unique collection of 179 small molecules used for DNA Damage and Repair research with targeting PARP,ATM/ATR,Topoisomerase,DNA/RNA Synthesis etc.
Epigenetics Compound Library

A unique collection of 467 compounds with biological activity used for epigenetic research and associated assays.
Ferroptosis Compound Library

A unique collection of 550 compounds used for exploring the mechanism of ferroptosis which is an iron-dependent form of non-apoptotic cell death.
Fragment Library

A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD).
Glutamine Metabolism Compound Library

A unique collection of 237 glutamine metabolism related compounds used for high throughput screening (HTS) and high content screening (HCS).
GPCR Compound Library

A unique collection of 738 small molecules targeting G protein coupled receptors for high throughput screening (HTS) and high content screening (HCS).
HIF-1 Signaling Pathway Compound Library

A unique collection of 449 HIF-1 signaling pathway compounds used for oxygen sensing related research.
Highly Selective Inhibitor Library

A unique collection of 318 validated highly selective inhibitors with covering over 123 targets.
Histone modification compound library

A unique collection of 112 small molecule compounds with biological activity used for histone modification research and associated assays.
HTS Library for Drug Discovery

A unique collection of 99040 compounds features numerous structurally diverse compounds and several alternate compositions.
Immunology/Inflammation Compound Library

A unique collection of 1055 small molecules with biological activity used for Immunology/Inflammation research and associated assays.
Inhibitor Library

A unique collection of 2770 inhibitors for high throughput screening (HTS) and high content screening (HCS).
Ion Channel Ligand Library

A unique collection of 232 small molecule modulators used for Ion channel research.
JAK/STAT compound library

A unique collection of 50 small molecules used for research in JAK-STAT signaling pathway.
Macrocyclic Compound Library

A unique collection of 106 macrocyclic compounds used for high throughput screening(HTS) and high content screening(HCS).
MAPK Inhibitor Library

A unique collection of 94 small molecule inhibitors used for MAPK signaling research.
Medicine Food Homology Compound Library

A unique collection of 122 medicine food homology compounds used for high throughput screening (HTS) and high content screening (HCS).
Metabolism Compound Library

A unique collection of 1365 small molecules with biological activity in numerous metabolic pathway: glycometabolism, lipid metabolism, proteolysis, etc.
Methylation Compound Library

A unique collection of 113 compounds used for researching the function of methylation in epigenetics,cancer,embryogenesis,etc.
Neuronal Signaling Compound Library

A unique collection of 1095 small molecule compounds with biological activity used for neurologic research and associated assays
NF-κB Signaling Compound Library

A unique collection of 40 small molecules used for NF-κB Signaling pathway research which plays a key role in immunology/inflammation and cancer.
Nucleoside Analogue Library

A unique collection of 135 nucleoside analogues used for high throughput screening(HTS) and high content screening(HCS).
Obesity Compound Library

A unique collection of 941 compounds used for research in obesity.
Protease Inhibitor Library

A unique collection of 227 small molecule inhibitors used for chemical genomics, high-throughput screening (HTS), and high content screening (HCS).
Small Molecule Immuno-Oncology Compound Library

A unique collection of 90 Immuno-Oncology small molecules used for oncotherapy in conjunction with other drugs.
Stem Cell Signaling Compound Library

A unique collection of 298 compounds with biological activity used for stem cell regulatory and signaling pathway research.
TGF-beta/Smad compound library

A unique collection of 60 small molecules with biological activity used for TGF-beta/Smad pathway research.
Tyrosine Kinase Inhibitor Library

A unique collection of 394 tyrosine kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).
Ubiquitination Compound Library

A unique collection of 151 small molecules for Ubiquitination related research.

Choose Your Country or Region

By Signaling Pathways

By product type