(L)-Dehydroascorbic acid

Catalog No.S3329 Synonyms: DHA

For research use only.

(L)-Dehydroascorbic acid (DHA) is an oxidized form of l-Ascorbic acid (AsA) that efficiently scavenges non-thermal plasma-induced hydroxyl radicals in the presence of thiols and fails to scavenge hydroxyl radicals by itself.

(L)-Dehydroascorbic acid Chemical Structure

CAS No. 490-83-5

Purity & Quality Control

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Biological Activity

Description

(L)-Dehydroascorbic acid (DHA) is an oxidized form of l-Ascorbic acid (AsA) that efficiently scavenges non-thermal plasma-induced hydroxyl radicals in the presence of thiols and fails to scavenge hydroxyl radicals by itself.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 35 mg/mL
(201.02 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 174.11
Formula

C6H6O6

CAS No. 490-83-5
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03402789 Not yet recruiting Drug: Docosahexaenoic Acid|Drug: Placebo Oral Tablet Amblyopia Johns Hopkins University January 1 2022 Phase 1|Phase 2
NCT05071690 Not yet recruiting -- DHA as Antioxidant Anti-inflammatory Immunomodulation Overcome Cytokine Storm Ministry of Health Saudi Arabia|Faculty of medicine kafr elshiekh university November 2021 --
NCT04965129 Not yet recruiting Drug: Placebo|Drug: Fish oil Lung Cancer Universidade Federal do Rio de Janeiro|Institutos Madrileño de Estudios Avanzados IMDEA|Oncoclínicas September 1 2021 Not Applicable
NCT05128240 Recruiting Dietary Supplement: Placebo|Dietary Supplement: Ceto 10 Skin Health Epax Norway AS|Møreforsking AS August 23 2021 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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