GPCR Compound Library

Catalog No.L2200

Offered in 96 or 384 well plate format

A unique collection of 1269 small molecules targeting G protein coupled receptors for high throughput screening (HTS) and high content screening (HCS).

Size Price  
Pre-dissolved In DMSO or Water
USD 14626
USD 21464

Selleck Chemicals compound library contributes and expedites
the investigation of treatments against COVID19

The researchers at the National Institute of Infectious Diseases, in Japan, successfully found anti-COVID19 drugs within 3 months of
screening FDA-approved drug library from Selleck Chemicals. They have already published this article doi: 10.1101/2020.04.14.039925.

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GPCR Compound Library Contents

Cited by 174 Publications

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer
  • Application of Kinase Inhibitor Library in colorectal cancer
    Nat Commun. 2019 16;10(1):2197
  • Application of FDA-approved Drug Library in antivirus
    Cell Res. 2019;29(9):739-753
  • Application of FDA-approved Drug Library in metabolism
    Mov Disord. 2019;34(3):323-334
  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia
    Blood. 2019 17;134(16):1323-1336
  • Application of Inhibitor Library in tumor immunology
    Cancer Immunol Res.2017;5(9):790-803

Description & Advantages

•A unique collection of 1269 small molecules targeting G protein coupled receptors for high throughput screening (HTS) and high content screening (HCS)
• All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity
• A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery
• It is estimated about 200 so-called orphan GPCRs are functionally unknown, as a result, use of our GPCR Small Molecule Compound Library for screening the functionally unknown GPCRs may yield potentially new GPCR-based drug candidates
• The GPCR compound library contains small molecules associated with receptors including 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, and ETA-receptor etc.
• Structurally diverse, medicinally active, and cell permeable
• Rich documentation with structure and customer reviews
• NMR and HPLC validated to ensure the highest purity

Product Details

Formulation: 1154 compounds pre-dissolved in 10mM DMSO, 77 compounds pre-dissolved in 10mM water, 34 compounds pre-dissolved in 2mM DMSO and 4 compounds pre-dissolved in 2mM water
Container: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability: in DMSO
Shipping: Blue ice or dry ice

GPCR Compound Library Composition

HTS Facility Partners

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