L-carnosine

Catalog No.S5226 Synonyms: Karnozin

For research use only.

L-carnosine (Karnozin) is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress.

L-carnosine Chemical Structure

CAS No. 305-84-0

Purity & Quality Control

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Biological Activity

Description L-carnosine (Karnozin) is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 226.23
Formula

C9H14N4O3

CAS No. 305-84-0
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1=C(NC=N1)CC(C(=O)O)NC(=O)CCN

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05371145 Not yet recruiting Biological: Carnosine Peripheral Arterial Disease University of Louisville June 1 2022 Phase 1|Phase 2
NCT04949607 Completed Dietary Supplement: Inulin fructooligosaccharide Brain Injury Chronic|Brain Injuries Traumatic Centre for Neuro Skills|University of Texas July 28 2021 Not Applicable
NCT03995810 Completed Dietary Supplement: Carnosine capsulle 2 g/day 8 weeks Multiple Sclerosis University of Novi Sad Faculty of Sport and Physical Education|CarnoMed June 15 2019 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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