Home Metabolism Amino Acids and Derivatives chemical L-Ornithine

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L-Ornithine Amino Acids and Derivatives chemical

Cat.No.S4857

L-ornithine ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.
L-Ornithine Amino Acids and Derivatives chemical Chemical Structure

Chemical Structure

Molecular Weight: 132.16

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Quality Control

Batch: S485701 Water]26 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 98%
98

Solubility

In vitro
Batch:

Water : 26 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : Insoluble

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In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 132.16 Formula

C5H12N2O2

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 70-26-8 -- Storage of Stock Solutions

Read more about storage stability stock solution CAS number

Mechanism of Action

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-09-03)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06465199 RECRUITING
Atypical Teratoid/Rhabdoid Tumor; Embryonal Tumor With Multilayered Rosettes; Ewing Sarcoma; Diffuse Intrinsic Pontine Glioma; Osteosarcoma; Neuroblastoma; DIPG Brain Tumor
Milton S. Hershey Medical Center
 2026-05-13 PHASE1; PHASE2
NCT07321912 RECRUITING
Osteosarcoma; Ewing Sarcoma
Milton S. Hershey Medical Center
 2026-06-05 PHASE2
NCT07468136 RECRUITING
Anaplastic Oligodendroglioma; Astrocytoma, IDH-Mutant, Grade 3; Astrocytoma, IDH-Mutant, Grade 4; Diffuse Astrocytoma; Glioblastoma, IDH-Wildtype; Malignant Glioma
Mayo Clinic
 2026-06-23 PHASE1; PHASE2
NCT06219174 SUSPENDED
Non Small Cell Lung Cancer; Lung Cancer
H. Lee Moffitt Cancer Center and Research Institute
 2024-08-07 PHASE1; PHASE2
NCT04301843 ACTIVE_NOT_RECRUITING
Neuroblastoma
Giselle Sholler
 2020-09-25 PHASE2
NCT04696029 RECRUITING
Medulloblastoma
Giselle Sholler
 2021-03-29 PHASE2

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