Ferroptosis Compound Library

Catalog No.L6400

Offered in 96 or 384 well plate format

A unique collection of 723 compounds used for exploring the mechanism of ferroptosis which is an iron-dependent form of non-apoptotic cell death.

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Ferroptosis Compound Library Contents

Description & Advantages

•A unique collection of 723 ferroptosis related compounds for high throughput screening (HTS) and high content screening (HCS)

•Targets iron, ROS, p53, NRF2, etc.

•Some compounds have been approved by the FDA

•Structurally diverse,medicinally active,and cell permeable

•Rich documentation with structure and bioactivity information

•NMR and HPLC validated to ensure high purity

Product Details

Formulation	672 compounds pre-dissolved in 10mM DMSO, 37 compounds pre-dissolved in 10mM water, 13 compounds pre-dissolved in 2mM DMSO and 1 compounds pre-dissolved in 2mM water
Container	96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability	12 months	-20°C	in DMSO
Stability	24 months	-80°C	in DMSO
Shipping	Blue ice or dry ice

Case Studies using Selleck Compound Libraries

Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

Nature.2019;574(7777):268-272
Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

Nat Commun. 2019 16;10(1):2197
Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

Cell Res. 2019;29(9):739-753
Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

Mov Disord. 2019;34(3):323-334
Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

Blood. 2019 17;134(16):1323-1336
Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

Cancer Immunol Res.2017;5(9):790-803

Ferroptosis Compound Library Composition

HTS Facility Partners