Levobupivacaine

For research use only.

Catalog No.S5181 Synonyms: Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine

Levobupivacaine Chemical Structure

CAS No. 27262-47-1

Levobupivacaine (Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine), the S (-)-enantiomer of bupivacaine, is a long-acting amide local anaesthetic used in analgesia and anaesthesia. Levobupivacaine exhibits effects on motor and sensory nerves by inhibiting the opening of voltage-gated sodium channels.

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Biological Activity

Description Levobupivacaine (Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine), the S (-)-enantiomer of bupivacaine, is a long-acting amide local anaesthetic used in analgesia and anaesthesia. Levobupivacaine exhibits effects on motor and sensory nerves by inhibiting the opening of voltage-gated sodium channels.
Targets
voltage-gated sodium channels [1]
()

Protocol

Solubility (25°C)

In vitro DMSO 58 mg/mL (201.08 mM)
Water Insoluble
Ethanol ''58 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 288.43
Formula

C18H28N2O

CAS No. 27262-47-1
Storage powder
in solvent
Synonyms Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04221568 Not yet recruiting Drug: Bupivacaine-fentanyl|Drug: levobupivacaine-fentanyl Labor Pain Assiut University March 1 2020 Phase 1
NCT03258697 Unknown status Drug: Levobupivacaine Hydrochloride Arthropathy Chang Gung Memorial Hospital October 17 2017 Not Applicable

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID