Levobupivacaine

Catalog No.S5181 Synonyms: Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine

For research use only.

Levobupivacaine (Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine), the S (-)-enantiomer of bupivacaine, is a long-acting amide local anaesthetic used in analgesia and anaesthesia. Levobupivacaine exhibits effects on motor and sensory nerves by inhibiting the opening of voltage-gated sodium channels.

Levobupivacaine Chemical Structure

CAS No. 27262-47-1

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Biological Activity

Description Levobupivacaine (Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine), the S (-)-enantiomer of bupivacaine, is a long-acting amide local anaesthetic used in analgesia and anaesthesia. Levobupivacaine exhibits effects on motor and sensory nerves by inhibiting the opening of voltage-gated sodium channels.
Targets
voltage-gated sodium channels [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 288.43
Formula

C18H28N2O

CAS No. 27262-47-1
Storage 3 years -20°C powder
2 years -80°C in solvent

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04221568 Unknown status Drug: Bupivacaine-fentanyl|Drug: levobupivacaine-fentanyl Labor Pain Assiut University March 1 2020 Phase 1
NCT03258697 Unknown status Drug: Levobupivacaine Hydrochloride Arthropathy Chang Gung Memorial Hospital October 17 2017 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-01-17)

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