HomeCompound LibrariesFDA-approved Drug Library

FDA-approved Drug Library

Cat.No.L1300

A unique collection of 3183 approved drugs and API included in pharmacopoeia for high throughput screening (HTS) and high content screening (HCS).

96 well plates

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Cited by 698 Publications

FDA-approved Drug Library Contents

Description & Advantages

• A unique collection of 3183 approved drugs and API included in pharmacopoeia for high throughput screening (HTS) and high content screening (HCS)
 
• All drugs were from approved institutions such as FDA,EMA,HMA,CFDA,PMDA,or pharmacopoeia such as USP,BP,EP,JP,Ph.Int,etc
 
• Provides the New Drug Application (NDA) or Abbreviated New Drug Application (ANDA) information of FDA  approved drugs
 
• Locate new targets for old drugs
 
• Bioactivity and safety confirmed by clinical trials
 
• Related to oncology, cardiology, anti-inflammatory, immunology, neuropsychiatry, analgesia etc
 
• Structurally diverse, medicinally active, and cell permeable
 
• Rich documentation with structure and customer reviews
 
• NMR and HPLC validated to ensure high purity
 
• Here are the approved institutions of approved drugs in this library:
 
Approved institution Full name Country
                FDA U.S. Food and Drug Administration United States of America  
                CFDA China Food and Drug Administration China
                EMA European Medicines Agency European
                HMA Heads Of Medicines Agency European
                NDC National Drug Code United States of America
                PMDA Pharmaceuticals and Medical Devices Agency Japan
                DMF Drug Master File United States of America

 

Product Details

Formulation 2809 compounds pre-dissolved in 10mM DMSO, 271 compounds pre-dissolved in 10mM water, 82 compounds pre-dissolved in 2mM DMSO, 19 compounds pre-dissolved in 2mM water and 2 compounds pre-dissolved in 2mg/ml DMSO
Container 96 Deep Well Plate Sealed With Aluminum Foil
Stability 12 months -20°C in DMSO
24 months -80°C in DMSO
Shipping Blue ice or dry ice

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

    Nature.2019;574(7777):268-272

  • Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

    Nat Commun. 2019 16;10(1):2197

  • Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

    Cell Res. 2019;29(9):739-753

  • Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

    Mov Disord. 2019;34(3):323-334

  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

    Blood. 2019 17;134(16):1323-1336

  • Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

    Cancer Immunol Res.2017;5(9):790-803

FDA-approved Drug Library Composition

HTS Facility Partners

  • Collaborating with Seleck: Yale University | Yale Center for Molecular Discovery
  • Collaborating with Seleck: Carbone Cancer Center | University of Wisconsin-Madison
  • Collaborating with Seleck: University of Colorado Denver | CU Denver
  • Collaborating with Seleck: Leibniz-Forschungsinstitut für Molekulare Pharmakologie: Leibniz-FMP
  • Collaborating with Seleck: UCSF_University of California San Francisco
  • Collaborating with Seleck: KU | High Throughput Screening Laboratory
  • Collaborating with Seleck: CIBIO
  • Collaborating with Seleck: Perelman school of medicine | University of Pennsylvania