TGF-beta/Smad compound library

Catalog No.L5600

Offered in 96 or 384 well plate format

A unique collection of 135 small molecules with biological activity used for TGF-beta/Smad pathway research.

Selleck Chemicals compound library contributes and expedites
the investigation of treatments against COVID19

The researchers at the National Institute of Infectious Diseases, in Japan, successfully found anti-COVID19 drugs within 3 months of
screening FDA-approved drug library from Selleck Chemicals. They have already published this article doi: 10.1101/2020.04.14.039925.

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TGF-beta/Smad compound library Contents

Cited by 205 Publications

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer
    Nature.2019;574(7777):268-272
  • Application of Kinase Inhibitor Library in colorectal cancer
    Nat Commun. 2019 16;10(1):2197
  • Application of FDA-approved Drug Library in antivirus
    Cell Res. 2019;29(9):739-753
  • Application of FDA-approved Drug Library in metabolism
    Mov Disord. 2019;34(3):323-334
  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia
    Blood. 2019 17;134(16):1323-1336
  • Application of Inhibitor Library in tumor immunology
    Cancer Immunol Res.2017;5(9):790-803

Description & Advantages

• A unique collection of 135 small molecule compounds  for high throughput screening(HTS) and high content screening (HCS).
 
• Target includes TGF-beta/Smad,TGF-β Receptor,PKC, ROCK and RAS
 
• A useful tool for finding tumor therapeutic mechanism and  new targets.
 
• For studying human diseases, exploring the pathogenesis of diseases such as cancer, and opening noval therapeutic ways. 
 
• Structurally diverse, medicinally active, and cell permeable.
 
• Rich documentation with structure description, target information, IC50 values and customer reviews.
 
• NMR and HPLC validated to ensure high purity.

 

 

Product Details

Formulation: 130 compounds pre-dissolved in 10mM DMSO, 2 compounds pre-dissolved in 10mM water and 3 compounds pre-dissolved in 2mM DMSO
Container: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability: in DMSO
in DMSO
Shipping: Blue ice or dry ice

TGF-beta/Smad compound library Composition

HTS Facility Partners

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