TGF-beta/Smad compound library

Catalog No.L5600

Offered in 96 or 384 well plate format

A unique collection of 121 small molecules with biological activity used for TGF-beta/Smad pathway research.

Size Price  
Pre-dissolved In DMSO or Water
USD 3630

Selleck Chemicals compound library contributes and expedites
the investigation of treatments against COVID19

The researchers at the National Institute of Infectious Diseases, in Japan, successfully found anti-COVID19 drugs within 3 months of
screening FDA-approved drug library from Selleck Chemicals. They have already published this article doi: 10.1101/2020.04.14.039925.

You Could Select:

Customize Library

TGF-beta/Smad compound library Contents

Download the TGF-beta/Smad compound library - SDF
Download the TGF-beta/Smad compound library - XLSX
Download the Compound Library Usage Instructions-pdf

Cited by 125 Publications

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer
    Nature.2019;574(7777):268-272
  • Application of Kinase Inhibitor Library in colorectal cancer
    Nat Commun. 2019 16;10(1):2197
  • Application of FDA-approved Drug Library in antivirus
    Cell Res. 2019;29(9):739-753
  • Application of FDA-approved Drug Library in metabolism
    Mov Disord. 2019;34(3):323-334
  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia
    Blood. 2019 17;134(16):1323-1336
  • Application of Inhibitor Library in tumor immunology
    Cancer Immunol Res.2017;5(9):790-803

Description & Advantages

• A unique collection of 121 small molecule compounds  for high throughput screening(HTS) and high content screening (HCS).
 
• Target includes TGF-beta/Smad,TGF-β Receptor,PKC, ROCK and RAS
 
• A useful tool for finding tumor therapeutic mechanism and  new targets.
 
• For studying human diseases, exploring the pathogenesis of diseases such as cancer, and opening noval therapeutic ways. 
 
• Structurally diverse, medicinally active, and cell permeable.
 
• Rich documentation with structure description, target information, IC50 values and customer reviews.
 
• NMR and HPLC validated to ensure high purity.

 

 

Product Details

Formulation: 116 compounds pre-dissolved in 10mM DMSO, 2 compounds pre-dissolved in 10mM water and 3 compounds pre-dissolved in 2mM DMSO
Container: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability: in DMSO
in DMSO
Shipping: Blue ice or dry ice
Packaging: Inert gas

TGF-beta/Smad compound library Composition

HTS Facility Partners

See Other Libraries

  • FDA-approved Drug Library

    A unique collection of 2747 approved drugs for high throughput screening (HTS) and high content screening (HCS).

  • FDA-approved & Passed Phase I Drug Library

    A unique collection of 3059 drugs that are marketed around the world or have passed clinical phase 1 and can be used for high throughput screening (HTS) and high content screening (HCS).

  • Preclinical/Clinical Compound Library

    A unique collection of 2913 preclinical and clinical compounds for high throughput screening (HTS) and high content screening (HCS).

  • Bioactive Compound Library-I

    A unique collection of 7377 bioactive compounds for high throughput screening (HTS) and high content screening (HCS).

  • Bioactive Compound Library-Ⅱ

    A unique collection of 5309 bioactive compounds for high throughput screening (HTS) and high content screening (HCS).

  • Kinase Inhibitor Library

    A unique collection of 1617 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Express-Pick Library

    A unique collection of 3010 chemical compounds featured different core structures and structural diversities respectively for high throughput screening (HTS) and high content screening (HCS).

  • Natural Product Library

    A unique collection of 2370 natural products for high throughput screening (HTS) and high content screening (HCS).

  • Human Endogenous Metabolite Compound Library

    887 small collections of human endogenous metabolites, involving multiple metabolic pathways, which can be used for high-throughput screening, opening up new ways for humans to treat various diseases such as tumors.

  • Alkaloid Compound Library

    A unique collection of 269 alkaloid compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Angiogenesis Related compound Library

    A unique collection of 409 small molecules used for angiogenesis research targeting Bcr-Abl,BTK,HIF,VEGFR,FGFR,FAK,etc.

  • Anti-Aging Compound Library

    A unique collection of 2324 anti-aging compounds used for aging related research.

  • Anti-alzheimer Disease Compound Library

    A unique collection of 485 small molecules for exploring the mechanism of alzheimer's disease.

  • Antibiotics compound Library

    A unique collection of 417 antibiotics used for anti- research in order to identify drug target and open up new mechanism and ways to treat human disease.

  • Anti-cancer Compound Library

    A unique collection of 3550 anti-cancer compounds for multiple cancers: Breast Cancer, Leukemia, Lung Cancer, Lymphoma, etc.

  • Anti-cancer Compound Library-Ⅱ

    A unique collection of 922 compounds with anticancer activity which has been verified by broad institute,half of the compounds are non-oncology drugs.

  • Anti-cancer Metabolism Compound Library

    A unique collection of 321 small molecules for cancer metabolism research.

  • Anti-Cardiovascular Disease Compound Library

    A unique collection of 700 anti-cardiovascular disease related compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Anti-diabetic Compound Library

    A unique collection of 150 small molecules for exploring the development of diabetes.

  • Anti-infection Compound Library

    A unique collection of 1325 anti-infection compounds with biological activity of antibacterial,antifungal,antiviral,etc.

  • Antioxidant Compound Library

    A unique collection of 426 compounds used for exploring the relationship between anti-oxidation and some diseases such as aging,cancer,alzheimer's disease,parkinson's disease,diabetes,etc.

  • Anti-parasitic Compound Library

    A unique collection of 171 anti-parasitic compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Antiviral Compound Library

    A unique collection of 458 antiviral compounds used for exploring novel antiviral drug.

  • Apoptosis Compound Library

    A unique collection of 1100 small molecules used for apoptosis research targeting Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survivin, etc.

  • Autophagy Compound Library

    A unique collection of 1029 small molecules with autophagy-inducing or autophagy-inhibiting activity.

  • Cambridge Cancer Compound Library

    A unique collection of 247 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS).

  • Cell Cycle compound library

    A unique collection of 120 small molecule compounds used for cell cycle and related diseases research.

  • CNS-Penetrant Compound Library

    A unique collection of 424 CNS-Penetrant compounds with biological activity for neurologic research.

  • Covalent Inhibitor Library

    A unique collection of 109 covalent Inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Cytoskeletal Signaling Pathway Compound Library

    A unique collection of 184 compounds used for research in cytoskeleton and cytoskeletal interactions.

  • DNA Damage/DNA Repair compound Library

    A unique collection of 569 small molecules used for DNA Damage and Repair research with targeting PARP,ATM/ATR,Topoisomerase,DNA/RNA Synthesis etc.

  • Drug-like Compound Library

    A unique collection of 2081 drug-like compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Endoplasmic Reticulum Stress Compound Library

    A unique collection of 93 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Epigenetics Compound Library

    A unique collection of 649 compounds with biological activity used for epigenetic research and associated assays.

  • FDA-approved Anticancer Drug Library

    A unique collection of 1567 approved drugs with anticancer activity used for high throughput screening(HTS) and high content screening(HCS).

  • Ferroptosis Compound Library

    A unique collection of 547 compounds used for exploring the mechanism of ferroptosis which is an iron-dependent form of non-apoptotic cell death.

  • Flavonoid Compound Library

    A unique collection of 185 flavonoid compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Fragment Library

    A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD).

  • Glutamine Metabolism Compound Library

    A unique collection of 439 glutamine metabolism related compounds used for high throughput screening (HTS) and high content screening (HCS).

  • Glycolysis Compound Library

    A unique collection of 396 glycolysis related compounds used for high throughput screening(HTS) and high content screening(HCS).

  • GPCR Compound Library

    A unique collection of 1130 small molecules targeting G protein coupled receptors for high throughput screening (HTS) and high content screening (HCS).

  • Gut Microbial Metabolite Library

    A unique collection of 91 gut microbial metabolites used for high throughput screening(HTS) and high content screening(HCS).

  • HIF-1 Signaling Pathway Compound Library

    A unique collection of 447 HIF-1 signaling pathway compounds used for oxygen sensing related research.

  • Highly Selective Inhibitor Library

    A unique collection of 462 validated highly selective inhibitors with covering over 123 targets.

  • Histone modification compound library

    A unique collection of 226 small molecule compounds with biological activity used for histone modification research and associated assays.

  • HTS Library for Drug Discovery

    A unique collection of 99040 compounds features numerous structurally diverse compounds and several alternate compositions.

  • Immunology/Inflammation Compound Library

    A unique collection of 2337 small molecules with biological activity used for Immunology/Inflammation research and associated assays.

  • Inhibitor Library

    A unique collection of 3456 inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Ion Channel Ligand Library

    A unique collection of 231 small molecule modulators used for Ion channel research.

  • JAK/STAT compound library

    A unique collection of 50 small molecules used for research in JAK-STAT signaling pathway.

  • Macrocyclic Compound Library

    A unique collection of 188 macrocyclic compounds used for high throughput screening(HTS) and high content screening(HCS).

  • MAPK Inhibitor Library

    A unique collection of 215 small molecule inhibitors used for MAPK signaling research.

  • Medicine Food Homology Compound Library

    A unique collection of 376 medicine food homology compounds used for high throughput screening (HTS) and high content screening (HCS).

  • Metabolism Compound Library

    A unique collection of 2478 small molecules with biological activity in numerous metabolic pathway: glycometabolism, lipid metabolism, proteolysis, etc.

  • Methylation Compound Library

    A unique collection of 112 compounds used for researching the function of methylation in epigenetics,cancer,embryogenesis,etc.

  • Natural Organic Compound Library

    A unique collection of 1127 plant-derived natural organic compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Neuronal Signaling Compound Library

    A unique collection of 1381 small molecule compounds with biological activity used for neurologic research and associated assays

  • NF-κB Signaling Compound Library

    A unique collection of 382 small molecules used for NF-κB signaling pathway research which plays a key role in immunology/inflammation and cancer.

  • Nucleoside Analogue Library

    A unique collection of 156 nucleoside analogues used for high throughput screening(HTS) and high content screening(HCS).

  • Obesity Compound Library

    A unique collection of 936 compounds used for research in obesity.

  • Phenotypic Screening Library

    A unique collection of 3751 bioactive compounds with identified targets used for phenotypic Screening.

  • PI3K/Akt Inhibitor Library

    A unique collection of 299 small molecule inhibitors used for PI3K/Akt/mTOR pathway research.

  • Protease Inhibitor Library

    A unique collection of 319 small molecule inhibitors used for chemical genomics, high-throughput screening (HTS), and high content screening (HCS).

  • Protein-protein Interaction Inhibitor Library

    A unique collection of 188 protein-protein Interaction(PPI) Inhibitors used for high throughput screening(HTS) and high content screening(HCS).

  • Pyroptosis Compound Library

    A unique collection of 771 pyroptosis related compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Small Molecule Immuno-Oncology Compound Library

    A unique collection of 176 Immuno-Oncology small molecules used for oncotherapy in conjunction with other drugs.

  • Stem Cell Signaling Compound Library

    A unique collection of 491 compounds with biological activity used for stem cell regulatory and signaling pathway research.

  • Traditional Chinese Medicine Library

    A unique collection of 1044 traditional chinese medicine(TCM) monomer compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Tyrosine Kinase Inhibitor Library

    A unique collection of 498 tyrosine kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Ubiquitination Compound Library

    A unique collection of 193 small molecules for Ubiquitination related research.