TGF-beta/Smad compound library

Catalog No.L5600

Offered in 96 or 384 well plate format

A unique collection of 60 small molecules with biological activity used for TGF-beta/Smad pathway research.

Size Price  
Pre-dissolved In DMSO or Water
USD 1800

You Could Select:

Customize Library

TGF-beta/Smad compound library Contents

Download the TGF-beta/Smad compound library - SDF
Download the TGF-beta/Smad compound library - XLSX

Cited by 36 Publications

Description & Advantages

• A unique collection of 60 small molecule compounds  for high throughput screening(HTS) and high content screening (HCS).
 
• Target includes TGF-beta/Smad,TGF-β Receptor,PKC, ROCK and RAS
 
• A useful tool for finding tumor therapeutic mechanism and  new targets.
 
• For studying human diseases, exploring the pathogenesis of diseases such as cancer, and opening noval therapeutic ways. 
 
• Structurally diverse, medicinally active, and cell permeable.
 
• Rich documentation with structure description, target information, IC50 values and customer reviews.
 
• NMR and HPLC validated to ensure high purity.

 

 

Product Details

Formulation: 56 compounds pre-dissolved in 10mM DMSO, 2 compounds pre-dissolved in 10mM water and 2 compounds pre-dissolved in 2mM DMSO
Container: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability: in DMSO
in DMSO
Shipping: Blue ice or dry ice
Packaging: Inert gas

TGF-beta/Smad compound library Composition

HTS Facility Partners

See Other Libraries

  • FDA-approved Drug Library

    A unique collection of 2684 approved drugs for high throughput screening (HTS) and high content screening (HCS).

  • Drug Repurposing Library

    A unique collection of 2827 drugs that are marketed around the world or have passed clinical phase 1 and can be used for high throughput screening (HTS) and high content screening (HCS).

  • Preclinical/Clinical Compound Library

    A unique collection of 2565 preclinical and clinical compounds for high throughput screening (HTS) and high content screening (HCS).

  • Bioactive Compound Library-I

    A unique collection of 6913 bioactive compounds for high throughput screening (HTS) and high content screening (HCS).

  • Bioactive Compound Library-Ⅱ

    A unique collection of 5309 bioactive compounds for high throughput screening (HTS) and high content screening (HCS).

  • Kinase Inhibitor Library

    A unique collection of 1255 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Express-Pick Library

    A unique collection of 4208 chemical compounds featured different core structures and structural diversities respectively for high throughput screening (HTS) and high content screening (HCS).

  • Natural Product Library

    A unique collection of 2054 natural products for high throughput screening (HTS) and high content screening (HCS).

  • Human Endogenous Metabolite Compound Library

    525 small collections of human endogenous metabolites, involving multiple metabolic pathways, which can be used for high-throughput screening, opening up new ways for humans to treat various diseases such as tumors.

  • Angiogenesis Related compound Library

    A unique collection of 113 small molecules used for angiogenesis research targeting Bcr-Abl,BTK,HIF,VEGFR,FGFR,FAK,etc.

  • Anti-Aging Compound Library

    A unique collection of 1504 anti-aging compounds used for aging related research.

  • Anti-alzheimer Disease Compound Library

    A unique collection of 486 small molecules for exploring the mechanism of Alzheimer's disease.

  • Antibiotics compound Library

    A unique collection of 308 antibiotics used for anti- research in order to identify drug target and open up new mechanism and ways to treat human disease.

  • Anti-cancer Compound Library

    A unique collection of 1933 anti-cancer compounds for multiple cancers: Breast Cancer, Leukemia, Lung Cancer, Lymphoma, etc.

  • Anti-cancer Metabolism Compound Library

    A unique collection of 195 small molecules for cancer metabolism research.

  • Anti-diabetic Compound Library

    A unique collection of 152 small molecules for exploring the development of diabetes.

  • Anti-infection Compound Library

    A unique collection of 930 anti-infection compounds with biological activity of antibacterial,antifungal,antiviral,etc.

  • Antioxidant Compound Library

    A unique collection of 429 compounds used for exploring the relationship between anti-oxidation and some diseases such as aging,cancer,alzheimer's disease,parkinson's disease,diabetes,etc.

  • Antiviral Compound Library

    A unique collection of 349 antiviral compounds used for exploring novel antiviral drug.

  • Apoptosis Compound Library

    A unique collection of 693 small molecules used for apoptosis research targeting Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survivin, etc.

  • Autophagy Compound Library

    A unique collection of 822 small molecules with autophagy-inducing or autophagy-inhibiting activity.

  • Cambridge Cancer Compound Library

    A unique collection of 247 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS).

  • Cell Cycle compound library

    A unique collection of 120 small molecule compounds used for cell cycle and related diseases research.

  • CNS-Penetrant Compound Library

    A unique collection of 307 CNS-Penetrant compounds with biological activity for neurologic research.

  • Covalent Inhibitor Library

    A unique collection of 81 covalent Inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Cytoskeletal Signaling Pathway Compound Library

    A unique collection of 185 compounds used for research in cytoskeleton and cytoskeletal interactions.

  • DNA Damage/DNA Repair compound Library

    A unique collection of 179 small molecules used for DNA Damage and Repair research with targeting PARP,ATM/ATR,Topoisomerase,DNA/RNA Synthesis etc.

  • Epigenetics Compound Library

    A unique collection of 467 compounds with biological activity used for epigenetic research and associated assays.

  • Ferroptosis Compound Library

    A unique collection of 76 compounds used for exploring the mechanism of ferroptosis which is an iron-dependent form of non-apoptotic cell death.

  • Fragment Library

    A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD).

  • Glutamine Metabolism Compound Library

    A unique collection of 237 glutamine metabolism related compounds used for high throughput screening (HTS) and high content screening (HCS).

  • GPCR Compound Library

    A unique collection of 738 small molecules targeting G protein coupled receptors for high throughput screening (HTS) and high content screening (HCS).

  • HIF-1 Signaling Pathway Compound Library

    A unique collection of 449 HIF-1 signaling pathway compounds used for oxygen sensing related research.

  • Highly Selective Inhibitor Library

    A unique collection of 318 validated highly selective inhibitors with covering over 123 targets.

  • Histone modification compound library

    A unique collection of 112 small molecule compounds with biological activity used for histone modification research and associated assays.

  • HTS Library for Drug Discovery

    A unique collection of 99040 compounds features numerous structurally diverse compounds and several alternate compositions.

  • Immunology/Inflammation Compound Library

    A unique collection of 1055 small molecules with biological activity used for Immunology/Inflammation research and associated assays.

  • Inhibitor Library

    A unique collection of 2770 inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Ion Channel Ligand Library

    A unique collection of 232 small molecule modulators used for Ion channel research.

  • JAK/STAT compound library

    A unique collection of 50 small molecules used for research in JAK-STAT signaling pathway.

  • MAPK Inhibitor Library

    A unique collection of 94 small molecule inhibitors used for MAPK signaling research.

  • Medicine Food Homology Compound Library

    A unique collection of 122 medicine food homology compounds used for high throughput screening (HTS) and high content screening (HCS).

  • Metabolism Compound Library

    A unique collection of 1366 small molecules with biological activity in numerous metabolic pathway: glycometabolism, lipid metabolism, proteolysis, etc.

  • Methylation Compound Library

    A unique collection of 113 compounds used for researching the function of methylation in epigenetics,cancer,embryogenesis,etc.

  • Neuronal Signaling Compound Library

    A unique collection of 1095 small molecule compounds with biological activity used for neurologic research and associated assays

  • NF-κB Signaling Compound Library

    A unique collection of 40 small molecules used for NF-κB Signaling pathway research which plays a key role in immunology/inflammation and cancer.

  • Obesity Compound Library

    A unique collection of 941 compounds used for research in obesity.

  • PI3K/Akt Inhibitor Library

    A unique collection of 173 small molecule inhibitors used for PI3K/Akt/mTOR pathway research.

  • Protease Inhibitor Library

    A unique collection of 227 small molecule inhibitors used for chemical genomics, high-throughput screening (HTS), and high content screening (HCS).

  • Small Molecule Immuno-Oncology Compound Library

    A unique collection of 90 Immuno-Oncology small molecules used for oncotherapy in conjunction with other drugs.

  • Stem Cell Signaling Compound Library

    A unique collection of 298 compounds with biological activity used for stem cell regulatory and signaling pathway research.

  • Tyrosine Kinase Inhibitor Library

    A unique collection of 394 tyrosine kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Ubiquitination Compound Library

    A unique collection of 151 small molecules for Ubiquitination related research.