HIF-1 Signaling Pathway Compound Library

Catalog No.L6100

Offered in 96 or 384 well plate format

A unique collection of 447 HIF-1 signaling pathway compounds used for oxygen sensing related research.

Size Price  
Pre-dissolved In DMSO or Water
USD 12516

Selleck Chemicals compound library contributes and expedites
the investigation of treatments against COVID19

The researchers at the National Institute of Infectious Diseases, in Japan, successfully found anti-COVID19 drugs within 3 months of
screening FDA-approved drug library from Selleck Chemicals. They have already published this article doi: 10.1101/2020.04.14.039925.

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HIF-1 Signaling Pathway Compound Library Contents

Download the HIF-1 Signaling Pathway Compound Library - SDF
Download the HIF-1 Signaling Pathway Compound Library - XLSX
Download the Compound Library Usage Instructions-pdf

Cited by 125 Publications

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer
    Nature.2019;574(7777):268-272
  • Application of Kinase Inhibitor Library in colorectal cancer
    Nat Commun. 2019 16;10(1):2197
  • Application of FDA-approved Drug Library in antivirus
    Cell Res. 2019;29(9):739-753
  • Application of FDA-approved Drug Library in metabolism
    Mov Disord. 2019;34(3):323-334
  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia
    Blood. 2019 17;134(16):1323-1336
  • Application of Inhibitor Library in tumor immunology
    Cancer Immunol Res.2017;5(9):790-803

Description & Advantages

•A unique collection of 447 HIF-1 signaling pathway compounds for high throughput screening (HTS) and high content screening (HCS)
 
•Targets HIF,HDAC,PI3K,MAPK,VHL,etc.
 
•Used for exploring the mechanism of cells' oxygen sensing
 
•Some compounds have been approved by the FDA
 
•Structurally diverse, medicinally active, and cell permeable
 
•Rich documentation with structure, IC50, and customer reviews
 
•NMR and HPLC validated to ensure high purity

Product Details

Formulation: 427 compounds pre-dissolved in 10mM DMSO, 8 compounds pre-dissolved in 10mM water and 12 compounds pre-dissolved in 2mM DMSO
Container: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability: in DMSO
in DMSO
Shipping: Blue ice or dry ice

HIF-1 Signaling Pathway Compound Library Composition

HTS Facility Partners

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