Fragment Library

Catalog No.L1600

Offered in 96 or 384 well plate format

A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD).

Selleck Chemicals compound library contributes and expedites
the investigation of treatments against COVID19

The researchers at the National Institute of Infectious Diseases, in Japan, successfully found anti-COVID19 drugs within 3 months of
screening FDA-approved drug library from Selleck Chemicals. They have already published this article doi: 10.1101/2020.04.14.039925.

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Fragment Library Contents

Cited by 1 Publications

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer
  • Application of Kinase Inhibitor Library in colorectal cancer
    Nat Commun. 2019 16;10(1):2197
  • Application of FDA-approved Drug Library in antivirus
    Cell Res. 2019;29(9):739-753
  • Application of FDA-approved Drug Library in metabolism
    Mov Disord. 2019;34(3):323-334
  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia
    Blood. 2019 17;134(16):1323-1336
  • Application of Inhibitor Library in tumor immunology
    Cancer Immunol Res.2017;5(9):790-803

Description & Advantages

• A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD)
• FBDD has emerged as an alternative approach for high-throughput screening (HTS) in discovering drug
• These fragments with low molecular weight are extremely suitable for screening clinical candidates with good drug-like properties,and more and more compounds discovered by FBDD are entering the clinic
• FBDD can save research cost and make it easier to screen high-performance drugs
  Range Average
MolWeight 92 to 291 164.8
LogP <3.8 1.5
Num_H_Acceptors 0 to 6 2.4
Num_H_Donors 0 to 3 1
Num_RotatableBonds 0 to 8 1.5
PSA 0 to 99 8


Product Details

Formulation: 1015 compounds pre-dissolved in 10mM DMSO
Container: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability: in DMSO
Shipping: Blue ice or dry ice

Fragment Library Composition

HTS Facility Partners

See Other Libraries