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L-(+)-Ergothioneine

Name: L-(+)-Ergothioneine
Brand: Selleck Chemicals
SKU: E2759
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.E2759

L-(+)-Ergothioneine(Ergothioneine), an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant.

Quality Control

Batch: E275901 Water]46 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 99.99%

Cited in Nature Medicine for its top-tier quality
COA
HPLC
SDS/MSDS
Datasheet

99.99

Related Targets	PROTAC Dyes Antineoplastic and Immunosuppressive Antibiotics ADC Cytotoxin Selection Antibiotics for Transfected Cell Antibiotics for Mammalian Cell Culture ADC Linker Molecular Glues Hydrotropic Agents Antibiotics for Plant Cell Culture
Other Others Inhibitors	Furimazine (PBI 3939) Guanidinoacetic acid Blebbistatin Polybrene (Hexadimethrine Bromide) Silibinin (NSC 651520) Palmitic acid Carbazochrome sodium sulfonate (AC-17) 4-Methylumbelliferone (4-MU) Sesamin Osthole

Solubility

In vitro
Batch:

Water : 46 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	229.3	Formula	C₉H₁₅N₃O₂S	Storage (From the date of receipt)	3 years -20°C powder
CAS No.	497-30-3	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Read more about storage stability stock solution CAS number

Mechanism of Action

References	[1] https://pubmed.ncbi.nlm.nih.gov/30721726/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-06-11)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07220187	NOT_YET_RECRUITING	Richter Syndrome; Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma; Transformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell Lymphoma	SWOG Cancer Research Network	2026-08-31	PHASE3
NCT06477939	NOT_YET_RECRUITING	Glioblastoma	Institut de cancérologie Strasbourg Europe	2025-01-01	PHASE3
NCT07437287	NOT_YET_RECRUITING	Biliary Tract Cancer (BTC)	UNICANCER	2026-07	PHASE2; PHASE3
NCT07464886	RECRUITING	Mild Depression	University of Cincinnati	2026-02-26	PHASE3
NCT07615296	NOT_YET_RECRUITING	Atherosclerotic Cardiovascular Disease (ASCVD)	Beijing Anzhen Hospital	2027-01-01
NCT06822478	RECRUITING	Leishmaniasis, Cutaneous	Universidad de Antioquia	2026-03-11	PHASE3

Tech Support

Handling Instructions

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