Home Protein Tyrosine Kinase NF-κB inhibitor - JAK inhibitor - EGFR inhibitor - c-Met inhibitor - Apoptosis related activator - Caspase activator - PARP inhibitor Licochalcone D For research use only.

Licochalcone D

Synonyms: Lico D, LCD, LD

Licochalcone D (Lico D, LCD, LD), a flavonoid isolated from a Chinese medicinal plant Glycyrrhiza inflata, has antioxidant, anti-inflammatory and anti-cancer properties. Licochalcone D inhibit phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone D inhibits JAK2, EGFR and Met (c-Met) activities and induces ROS-dependent apoptosis. Licochalcone D also induces caspases activation and poly (ADP-ribose) polymerase (PARP) cleavage.

Licochalcone D Chemical Structure

Licochalcone D Chemical Structure

CAS: 144506-15-0

Purity & Quality Control

Batch: S689901 DMSO] 100 mg/mL] false] Ethanol] 20 mg/mL] false] Water] Insoluble] false Purity: 99.95%
99.95

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Biological Activity

Description Licochalcone D (Lico D, LCD, LD), a flavonoid isolated from a Chinese medicinal plant Glycyrrhiza inflata, has antioxidant, anti-inflammatory and anti-cancer properties. Licochalcone D inhibit phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone D inhibits JAK2, EGFR and Met (c-Met) activities and induces ROS-dependent apoptosis. Licochalcone D also induces caspases activation and poly (ADP-ribose) polymerase (PARP) cleavage.
Targets
NF-κB [1] JAK2 [2] EGFR [3] Met [3] Caspase [3] Click to View More Targets
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Chemical Information & Solubility

Molecular Weight 354.40 Formula

C21H22O5
CAS No. 144506-15-0 SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (282.16 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 20 mg/mL

Water : Insoluble


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