Peptide Products

Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum) acetate, an analog of the native somatostatin peptide, is a physiological inhibitor of growth hormone (GH). Lanreotide also has antitumoral effects.

Abaloparatide (BA058, BIM-44058, ITM-058) is a novel 34-amino acid peptide selected to be a potent and selective activator of the parathyroid hormone receptor (PTH1R) signaling pathway with an IC50 of 0.117 nM in SOST analysis.

Deslorelin Acetate is a synthetic analogue of gonadotrophin-releasing hormone (GnRH) that acts as a potent GnRH agonist.

Glatiramer acetate is a synthetic copolymer composed of a random mixture of four amino acids that modifies the immune response.

Bombesin, a tetradecapeptide, plays an important role in the release of gastrin and the activation of G-protein receptors.

GLP-1(7-36) amide human (Glucagon-like peptide-I(7-36) amide) is a physiological incretin hormone that stimulates insulin secretion.

Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis.

Neuropeptide Y (human, rat) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.

Obestatin(human) is a 23-amino acid amidated peptide that regulates appetite and gastrointestinal motility via its interaction with GPR39. Obestatin(human) can be used for weight loss.

Obestatin(rat), encoded by the Ghrelin gene, is a cpeptide, comprised of 23 amino acids. Obestatin(rat) suppresses food intake, inhibits jejunal contraction, and decreases body-weight gain. Obestatin is an endogenous ligand of G-protein coupled receptor 39 (GPR39). Obestatin(rat) has anti-inflammatory, anti-myocardial infarction and antioxidant activities.

Peptide YY (3-36) (human) is an endogenous appetite suppressing peptide. Peptide YY (PYY) (3-36), Human, a neuropeptide Y (NPY) Y2 receptor agonist, is a powerful inhibitor of intestinal secretion[1].

Peptide YY (PYY) is a gut hormone that regulates appetite and inhibits pancreatic secretion. Peptide YY (PYY) can mediate its effects through the Neuropeptide Y receptors.

Pasireotide (SOM230), a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors. Pasireotide can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide also exhibits antisecretory, antiproliferative, and proapoptotic activity.

Sermorelin, a 29 amino acid analogue of human growth hormone-releasing hormone (GHRH), is the shortest synthetic peptide with full biological activity of GHRH.

Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).

Xenin is a 25-amino acid peptide initially isolated from human gastric mucosa. Xenin is a gut hormone that can reduce food intake.

Dynorphin (1-17) (Dynorphin A (swine)), an endogenous opioid peptide, is a highy potent kappa opioid receptor (KOR) activator. Dynorphin A also serve as an agonist for other opioid receptors,  such as mu (MOR) and delta (DOR)[1].

Kassinin is a peptide derived from the Kassina frog. Kassinin belongs to tachykinin family of neuropeptides. Kassinin is secreted as a defense response, involving in neuropeptide signalling.

Abarelix (R3827; PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer treatment.

Nesiritide (Brain Natriuretic Peptide-32 human; BNP-32) is an agonist of natriuretic peptide receptors (NPRs).

Antide, a Gonadotropin-releasing hormone antagonist,  inhibits apoptosis of preovulatory follicle cells in rat ovary.

GLP-1(7-37) is an intestinal insulinotropic hormone that augments glucose induced insulin secretion.

TMPyP4 tosylate (TMP 1363), a quadruplex-specific ligand, inhibits the interaction between G-quadruplex (G4) and IGF-1 (Insulin-like growth factor type I). TMPyP4 tosylate is also a telomerase inhibitor with antitumor effects.

alpha-MSH TFA (α-MSH TFA, α-MSH Trifluoroacetate, alpha-MSH Trifluoroacetate,α-Melanocyte-stimulating hormone TFA, α-Melanocyte-stimulating hormone Trifluoroacetate) is a 13-amino acid peptide hormone. an endogenous MC4R agonist. alpha-MSH TFA is an endogenous MC3R and MC4R agonist with EC50s of 0.16 nM and 56 nM for hMC3R and hMC4R in Hepa cells, respectively.

PMX 205 is a cyclic hexapeptide that acts as a potent C5a receptor (C5aR, CD88) antagonist with an IC50 of 31 nM.

Apelin-13 can efficiently antagonize the APJ receptor with EC50 of 0.37 nM and result in suppress the forskolin-stimulated cAMP production.

(Ala13)-Apelin-13 is a potent APJ receptor antagonist and can prevent the apelin-induced reduction in gastric tone and motility.