FDA-approved & Passed Phase I Drug Library

Cat.No.L3800

A unique collection of 4200 drugs that are marketed around the world or have passed clinical phase 1 and can be used for high throughput screening (HTS) and high content screening (HCS).

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Specific Compounds
Quantities
96 or 384 well Plate Map
Dry/solid or DMSO solution

Cited by 335 Publications

FDA-approved & Passed Phase I Drug Library Contents

Description & Advantages

• A unique collection of 4200 drugs that are marketed around the world or have passed clinical phase 1 and can be used for high throughput screening (HTS) and high content screening (HCS)

•Drug repurposing, the application of known drugs to treat new disease indication, holds potential of rapid clinical impact at a lower cost than de novo drug development

• Safety confirmed by clinical phase 1

• Related to oncology, cardiology, anti-inflammatory, immunology, neuropsychiatry, analgesia etc

• Structurally diverse, medicinally active, and cell permeable.

• Rich documentation with structure, IC50, and customer reviews

• NMR and HPLC validated to ensure the highest purity

Product Details

Formulation	3768 compounds pre-dissolved in 10mM DMSO, 301 compounds pre-dissolved in 10mM water, 110 compounds pre-dissolved in 2mM DMSO, 19 compounds pre-dissolved in 2mM water and 2 compounds pre-dissolved in 2mg/ml DMSO
Container	96 Deep Well Plate Sealed With Aluminum Foil
Stability	12 months	-20°C	in DMSO
Stability	24 months	-80°C	in DMSO
Shipping	Blue ice or dry ice

Case Studies using Selleck Compound Libraries

Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

Nature.2019;574(7777):268-272
Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

Nat Commun. 2019 16;10(1):2197
Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

Cell Res. 2019;29(9):739-753
Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

Mov Disord. 2019;34(3):323-334
Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

Blood. 2019 17;134(16):1323-1336
Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

Cancer Immunol Res.2017;5(9):790-803