FDA-approved & Passed Phase I Drug Library

Catalog No.L3800

Offered in 96 or 384 well plate format

A unique collection of 3337 drugs that are marketed around the world or have passed clinical phase 1 and can be used for high throughput screening (HTS) and high content screening (HCS).

96 well box

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Cited by 225 Publications

Description & Advantages

• A unique collection of 3337 drugs that are marketed around the world or have passed clinical phase 1 and can be used for high throughput screening (HTS) and high content screening (HCS)

•Drug repurposing, the application of known drugs to treat new disease indication, holds potential of rapid clinical impact at a lower cost than de novo drug development

• Safety confirmed by clinical phase 1

• Related to oncology, cardiology, anti-inflammatory, immunology, neuropsychiatry, analgesia etc

• Structurally diverse, medicinally active, and cell permeable.

• Rich documentation with structure, IC50, and customer reviews

• NMR and HPLC validated to ensure the highest purity

Product Details
Formulation 2958 compounds pre-dissolved in 10mM DMSO, 273 compounds pre-dissolved in 10mM water, 87 compounds pre-dissolved in 2mM DMSO and 19 compounds pre-dissolved in 2mM water
Container 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability 12 months -20°C in DMSO
24 months -80°C in DMSO
Shipping Blue ice or dry ice
Case Studies using Selleck Compound Libraries
  • Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

    Nature.2019;574(7777):268-272

  • Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

    Nat Commun. 2019 16;10(1):2197

  • Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

    Cell Res. 2019;29(9):739-753

  • Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

    Mov Disord. 2019;34(3):323-334

  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

    Blood. 2019 17;134(16):1323-1336

  • Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

    Cancer Immunol Res.2017;5(9):790-803

FDA-approved & Passed Phase I Drug Library Composition

HTS Facility Partners