Anti-cancer Compound Library-Ⅱ

Catalog No.L7100

Offered in 96 or 384 well plate format

A unique collection of 914 compounds with anticancer activity which has been verified by broad institute,half of the compounds are non-oncology drugs.

96 well box

You could select:

Cited by 224 Publications

Description & Advantages
•The Broad Institute tested 4,518 drugs across 578 human cancer cell lines and found large number of non-oncology drugs selectively inhibited subsets of cancer cell lines(PMID:32613204)
 
•A unique collection of 914 compounds with anticancer activity which has been verified by broad institute used for high throughput screening(HTS) and high content screening(HCS)
 
•Targets DNA/RNA SynthesisHDACEGFRAurora KinaseTopoisomerase, etc.
 
•Some compounds have been approved by the FDA
 
•Structurally diverse,medicinally active,and cell permeable
 
•Rich documentation with structure and bioactivity information
 
•NMR and HPLC validated to ensure high purity
Product Details
Formulation 850 compounds pre-dissolved in 10mM DMSO, 20 compounds pre-dissolved in 10mM water, 42 compounds pre-dissolved in 2mM DMSO and 2 compounds pre-dissolved in 2mM water
Container 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability 12 months -20°C in DMSO
24 months -80°C in DMSO
Shipping Blue ice or dry ice
Case Studies using Selleck Compound Libraries
  • Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

    Nature.2019;574(7777):268-272

  • Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

    Nat Commun. 2019 16;10(1):2197

  • Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

    Cell Res. 2019;29(9):739-753

  • Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

    Mov Disord. 2019;34(3):323-334

  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

    Blood. 2019 17;134(16):1323-1336

  • Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

    Cancer Immunol Res.2017;5(9):790-803

Anti-cancer Compound Library-Ⅱ Composition

HTS Facility Partners