Anti-cancer Compound Library-Ⅱ

Catalog No.L7100

Offered in 96 or 384 well plate format

A unique collection of 914 compounds with anticancer activity which has been verified by broad institute,half of the compounds are non-oncology drugs.

Selleck Chemicals compound library contributes and expedites
the investigation of treatments against COVID19

The researchers at the National Institute of Infectious Diseases, in Japan, successfully found anti-COVID19 drugs within 3 months of
screening FDA-approved drug library from Selleck Chemicals. They have already published this article doi: 10.1101/2020.04.14.039925.

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Anti-cancer Compound Library-Ⅱ Contents

Cited by 205 Publications

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer
  • Application of Kinase Inhibitor Library in colorectal cancer
    Nat Commun. 2019 16;10(1):2197
  • Application of FDA-approved Drug Library in antivirus
    Cell Res. 2019;29(9):739-753
  • Application of FDA-approved Drug Library in metabolism
    Mov Disord. 2019;34(3):323-334
  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia
    Blood. 2019 17;134(16):1323-1336
  • Application of Inhibitor Library in tumor immunology
    Cancer Immunol Res.2017;5(9):790-803

Description & Advantages

•The Broad Institute tested 4,518 drugs across 578 human cancer cell lines and found large number of non-oncology drugs selectively inhibited subsets of cancer cell lines(PMID:32613204)
•A unique collection of 914 compounds with anticancer activity which has been verified by broad institute used for high throughput screening(HTS) and high content screening(HCS)
•Targets DNA/RNA Synthesis,HDAC,EGFR,Aurora Kinase,Topoisomerase,etc.
•Some compounds have been approved by the FDA
•Structurally diverse,medicinally active,and cell permeable
•Rich documentation with structure and bioactivity information
•NMR and HPLC validated to ensure high purity

Product Details

Formulation: 850 compounds pre-dissolved in 10mM DMSO, 20 compounds pre-dissolved in 10mM water, 42 compounds pre-dissolved in 2mM DMSO and 2 compounds pre-dissolved in 2mM water
Container: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability: in DMSO
Shipping: Blue ice or dry ice

Anti-cancer Compound Library-Ⅱ Composition

HTS Facility Partners

See Other Libraries