Pyroptosis Compound Library

Catalog No.L7400

Offered in 96 or 384 well plate format

A unique collection of 766 pyroptosis related compounds used for high throughput screening(HTS) and high content screening(HCS).

Selleck Chemicals compound library contributes and expedites
the investigation of treatments against COVID19

The researchers at the National Institute of Infectious Diseases, in Japan, successfully found anti-COVID19 drugs within 3 months of
screening FDA-approved drug library from Selleck Chemicals. They have already published this article doi: 10.1101/2020.04.14.039925.

Recently the accomplishment of this research, using Selleck Chemicals library, was reported on Japanese television

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Pyroptosis Compound Library Contents

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Download the Compound Library Usage Instructions-pdf

Cited by 205 Publications

Chem Soc Rev,2021,10.1039/d0cs01065k

PubMed: 34212944 ( click the link to review the publication )

Cell,2020,181(7):1518-1532.e14

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Cell Metab,2019,7;29(5):1166-1181.e6.

PubMed: 30799286 ( click the link to review the publication )

Nature,2017,546(7659):533-538

PubMed: 28614297 ( click the link to review the publication )

Nat Med,2014,20(8):954-60

PubMed: 24997607 ( click the link to review the publication )

Adv Sci (Weinh),2021,8(11):e2003558

PubMed: 34105277 ( click the link to review the publication )

Mol Cell,2021,S1097-2765(21)00314-2

PubMed: 33932349 ( click the link to review the publication )

J Am Chem Soc,2021,143(13):4979-4992

PubMed: 33761747 ( click the link to review the publication )

Sci Adv,2021,7(10)eabe7853

PubMed: 33674313 ( click the link to review the publication )

Nat Chem Biol,2021,10.1038/s41589-021-00751-4

PubMed: 33686292 ( click the link to review the publication )

Nat Commun,2021,12(1):1117

PubMed: 33602919 ( click the link to review the publication )

Nat Commun,2021,12(1):4360

PubMed: 34272384 ( click the link to review the publication )

Clin Cancer Res,2021,clincanres.4037.2020

PubMed: 33547197 ( click the link to review the publication )

Clin Cancer Res,2021,clincanres.5026.2020

PubMed: 34083237 ( click the link to review the publication )

Clin Cancer Res,2021,clincanres.0464.2021

PubMed: 34233959 ( click the link to review the publication )

Proc Natl Acad Sci U S A,2021,118(13)e2009620118

PubMed: 33762304 ( click the link to review the publication )

Brief Bioinform,2021,bbab113

PubMed: 33993214 ( click the link to review the publication )

EMBO Rep,2021,e51781

PubMed: 34323349 ( click the link to review the publication )

Cell Rep,2021,35(1):108940

PubMed: 33784499 ( click the link to review the publication )

Cell Rep,2021,35(1):108959

PubMed: 33811811 ( click the link to review the publication )

Cell Rep,2021,35(4):109024

PubMed: 33910005 ( click the link to review the publication )

PLoS Biol,2021,19(5):e3001221

PubMed: 33939688 ( click the link to review the publication )

Cancer Lett,2021,514:12-29

PubMed: 34022283 ( click the link to review the publication )

J Med Chem,2021,10.1021/acs.jmedchem.1c00367

PubMed: 34279931 ( click the link to review the publication )
J Exp Clin Cancer Res,2021,40(1):90

PubMed: 33676554 ( click the link to review the publication )

Cancers (Basel),2021,13(3)576

PubMed: 33540838 ( click the link to review the publication )

Clin Epigenetics,2021,13(1):54

PubMed: 33691794 ( click the link to review the publication )

Comput Struct Biotechnol J,2021,19:3674-3681

PubMed: 34285770 ( click the link to review the publication )

Cell Death Dis,2021,12(2):183

PubMed: 33589588 ( click the link to review the publication )

Acta Pharm Sin B,2021,11(1):181-202

PubMed: 33532188 ( click the link to review the publication )

Cancer Discov,2021,candisc.0872.2020

PubMed: 34127480 ( click the link to review the publication )

Mol Cancer Ther,2021,molcanther.MCT-20-0666-E.2020

PubMed: 33850004 ( click the link to review the publication )

Mol Cancer Ther,2021,molcanther.MCT-20-0377-A.2020

PubMed: 34108263 ( click the link to review the publication )

Front Cell Dev Biol,2021,9:673374

PubMed: 34211974 ( click the link to review the publication )

Clin Transl Allergy,2021,11(5):e12045

PubMed: 34322217 ( click the link to review the publication )

Neoplasia,2021,23(9):929-938

PubMed: 34329950 ( click the link to review the publication )

Stem Cell Res Ther,2021,12(1):151

PubMed: 33632328 ( click the link to review the publication )

ACS Infect Dis,2021,10.1021/acsinfecdis.0c00853

PubMed: 33599488 ( click the link to review the publication )

Eur J Med Chem,2021,223:113576

PubMed: 34153577 ( click the link to review the publication )

Am J Cancer Res,2021,11(1):215-235

PubMed: 33520370 ( click the link to review the publication )

J Immunol,2021,ji2000969

PubMed: 33568399 ( click the link to review the publication )

Glycobiology,2021,cwab048

PubMed: 34080004 ( click the link to review the publication )

Int J Mol Sci,2021,22(4)1750

PubMed: 33578647 ( click the link to review the publication )

Sci Rep,2021,11(1):4390

PubMed: 33623106 ( click the link to review the publication )

Sci Rep,2021,11(1):14062

PubMed: 34234256 ( click the link to review the publication )

J Biol Chem,2021,jbc.RA120.016477

PubMed: 33397709 ( click the link to review the publication )

Methods,2021,S1046-2023(21)00015-3

PubMed: 33453392 ( click the link to review the publication )

Biochem J,2021,BCJ20210257

PubMed: 34190988 ( click the link to review the publication )
Cancer Cytopathol,2021,10.1002/cncy.22448

PubMed: 34043284 ( click the link to review the publication )

Cancer Commun (Lond),2021,10.1002/cac2.12189

PubMed: 34196511 ( click the link to review the publication )

J Gastroenterol Hepatol,2021,10.1111/jgh.15490

PubMed: 33721913 ( click the link to review the publication )

Pathogens,2021,10(2)253

PubMed: 33672424 ( click the link to review the publication )

Cell Tissue Res,2021,10.1007/s00441-021-03496-7

PubMed: 34223980 ( click the link to review the publication )

J Biomol Struct Dyn,2021,1-17

PubMed: 34243699 ( click the link to review the publication )

Transl Oncol,2021,14(9):101147

PubMed: 34118569 ( click the link to review the publication )

Biochem Biophys Res Commun,2021,560:1-6

PubMed: 33965784 ( click the link to review the publication )

Hum Cell,2021,10.1007/s13577-021-00497-0

PubMed: 33555519 ( click the link to review the publication )

Hum Cell,2021,10.1007/s13577-021-00497-0

PubMed: 33611700 ( click the link to review the publication )

FEBS Open Bio,2021,11(5):1452-1464

PubMed: 33822489 ( click the link to review the publication )

J Toxicol Sci,2021,46(4):167-176

PubMed: 33814510 ( click the link to review the publication )

In Vivo,2021,35(2):761-777

PubMed: 33622869 ( click the link to review the publication )

Tohoku J Exp Med,2021,254(1):17-23

PubMed: 34011804 ( click the link to review the publication )

STAR Protoc,2021,2(1):100345

PubMed: 33665625 ( click the link to review the publication )

AAPS J,2021,23(2):35

PubMed: 33649974 ( click the link to review the publication )

Genes Cancer,2021,12:12-24

PubMed: 33884102 ( click the link to review the publication )

FASEB Bioadv,2021,3(5):334-355

PubMed: 33977234 ( click the link to review the publication )

Commun Biol,2021,4(1):573

PubMed: 33990679 ( click the link to review the publication )

NAR Cancer,2021,3(2):zcab018

PubMed: 34027408 ( click the link to review the publication )

Hemasphere,2021,5(7):e602

PubMed: 34136753 ( click the link to review the publication )

Viruses,2021,13(7)1255

PubMed: 34203149 ( click the link to review the publication )

Nat Commun,2020,14;11(1):1792.

PubMed: 32286289 ( click the link to review the publication )

Nucleic Acids Res,2020,48(20):11566-11576

PubMed: 33053158 ( click the link to review the publication )
Cancer Res,2020,15;80(4):832-842.

PubMed: 31888889 ( click the link to review the publication )

Cell Rep,2020,32(1):107845

PubMed: 32640215 ( click the link to review the publication )

EBioMedicine,2020,60:102988

PubMed: 32927276 ( click the link to review the publication )

Stem Cell Reports,2020,14(3):478-492

PubMed: 32084387 ( click the link to review the publication )

Cancer Lett,2020,469:195-206

PubMed: 31672491 ( click the link to review the publication )

Cancers (Basel),2020,12(6)E1418

PubMed: 32486290 ( click the link to review the publication )

Cell Death Dis,2020,2;11(3):158.

PubMed: 32123161 ( click the link to review the publication )

Cell Death Dis,2020,11(9):724

PubMed: 32895373 ( click the link to review the publication )

Signal Transduct Target Ther,2020,4;5:20.

PubMed: 32195002 ( click the link to review the publication )

Mol Ther Oncolytics,2020,30;17:169-179.

PubMed: 32346607 ( click the link to review the publication )

Cell Chem Biol,2020,20;27(2):197-205.e6.

PubMed: 31734178 ( click the link to review the publication )

Cell Chem Biol,2020,16;27(1):94-104.e5.

PubMed: 31902676 ( click the link to review the publication )

Carcinogenesis,2020,41(7):993-1004

PubMed: 31740922 ( click the link to review the publication )

Antimicrob Agents Chemother,2020,4;AAC.02523-19.

PubMed: 32366713 ( click the link to review the publication )

Toxicol Sci,2020,1;174(2):218-240.

PubMed: 32040181 ( click the link to review the publication )

Int J Mol Sci,2020,18;21(8):2825.

PubMed: 32325639 ( click the link to review the publication )

Sci Rep,2020,24;10(1):5318.

PubMed: 32210281 ( click the link to review the publication )

Vaccines (Basel),2020,8(1)E72

PubMed: 32041347 ( click the link to review the publication )

J Biol Chem,2020,27;jbc.RA120.012981.

PubMed: 32461254 ( click the link to review the publication )

Breast Cancer Res Treat,2020,179(2):337-347.

PubMed: 31655920 ( click the link to review the publication )

PLoS One,2020,15(1):e0228189

PubMed: 31999754 ( click the link to review the publication )

PLoS One,2020,15(5):e0233672

PubMed: 32469945 ( click the link to review the publication )

PLoS One,2020,15(5):e0233089

PubMed: 32459810 ( click the link to review the publication )

J Allergy Clin Immunol,2020,21;S0091-6749(20)30259-1.

PubMed: 32088305 ( click the link to review the publication )
bioRxiv,2020,doi:10.1101/2020.05.26.117770

PubMed: No ( click the link to review the publication )

Sarcoma,2020,2020:6312480

PubMed: 32565715 ( click the link to review the publication )

bioRxiv,2020,2020.04.20.051581

PubMed: 32511378 ( click the link to review the publication )

ACS Pharmacol Transl Sci,2020,3(6):1278-1292

PubMed: 33330842 ( click the link to review the publication )

Genome Biol,2019,20(1):253

PubMed: 31771620 ( click the link to review the publication )

Sci Adv,2019,5(6):eaav9784

PubMed: 31249867 ( click the link to review the publication )

Cell Rep,2019,5;26(6):1544-1556.e8.

PubMed: 30726737 ( click the link to review the publication )

Neuropsychopharmacology,2019,10.1038/s41386-018-0266-7

PubMed: 30518933 ( click the link to review the publication )

Drug Discov Today,2019,24(2):390-402

PubMed: 30399443 ( click the link to review the publication )

Cancers (Basel),2019,30;11(2):156.

PubMed: 30704052 ( click the link to review the publication )

Breast Cancer Res,2019,21(1):37

PubMed: 30845991 ( click the link to review the publication )

Anal Chem,2019,91(8):4995-5003

PubMed: 30813716 ( click the link to review the publication )

Cell Chem Biol,2019,21;26(2):235-243.e5.

PubMed: 30527999 ( click the link to review the publication )

Cancer Discov,2019,9(7):910-925

PubMed: 31048320 ( click the link to review the publication )

Neurobiol Aging,2019,76:24-34

PubMed: 30640040 ( click the link to review the publication )

mSphere,2019,4(3)e00047-19

PubMed: 31118297 ( click the link to review the publication )

Antimicrob Agents Chemother,2019,AAC.01470-19

PubMed: 31570393 ( click the link to review the publication )

Cancer Gene Ther,2019,10.1038/s41417-019-0127-5

PubMed: 31383953 ( click the link to review the publication )

Stem Cells Int,2019,2019:3435901

PubMed: 31871467 ( click the link to review the publication )

Biochem J,2019,476(15):2209-2219

PubMed: 31341008 ( click the link to review the publication )

Cancer Manag Res,2019,11:8391-8405

PubMed: 31571995 ( click the link to review the publication )

Breast Cancer Res Treat,2019,10.1007/s10549-019-05504-5

PubMed: 31784862 ( click the link to review the publication )

Acta Pharmacol Sin,2019,10.1038/s41401-019-0246-4

PubMed: 31197246 ( click the link to review the publication )

Cell Signal,2019,67:109508

PubMed: 31866490 ( click the link to review the publication )
Virology,2019,541:41-51

PubMed: 31826845 ( click the link to review the publication )

Molecules,2019,24(20)E3798

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Int J Parasitol Drugs Drug Resist,2019,10:28-37.

PubMed: 31015150 ( click the link to review the publication )

J Med Virol,2019,91(8):1440-1447.

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Bioengineered,2019,10(1):98-107

PubMed: 31023186 ( click the link to review the publication )

Kaohsiung J Med Sci,2019,10.1002/kjm2.12051

PubMed: 30896891 ( click the link to review the publication )

bioRxiv,2019,doi:10.1101/748129

PubMed: no ( click the link to review the publication )

Curr Protoc Chem Biol,2019,11(2):e64

PubMed: 30816629 ( click the link to review the publication )

Cancer Immunol Res,2019,7(9):1523-1534

PubMed: 31266784 ( click the link to review the publication )

Nat Commun,2018,9(1):1655

PubMed: 29695808 ( click the link to review the publication )

Cancer Res,2018,78(15):4344-4359

PubMed: 29844121 ( click the link to review the publication )

Cancer Res,2018,78(20):5731-5740

PubMed: 30135193 ( click the link to review the publication )

Cell Rep,2018,22(5):1185-1199

PubMed: 29386107 ( click the link to review the publication )

Elife,2018,7e35136

PubMed: 29979149 ( click the link to review the publication )

EBioMedicine,2018,28:80-89.

PubMed: 29396295 ( click the link to review the publication )

Cancer Discov,2018,8(4):498-515

PubMed: 29610289 ( click the link to review the publication )

Cancer Sci,2018,109(4):1220-1229

PubMed: 29453896 ( click the link to review the publication )

PLoS Negl Trop Dis,2018,12(3):e0006326

PubMed: 29522528 ( click the link to review the publication )

Antimicrob Agents Chemother,2018,62(12)e01302-18

PubMed: 30224531 ( click the link to review the publication )

Sci Rep,2018,8(1):13106

PubMed: 30166612 ( click the link to review the publication )

Sci Rep,2018,21;8(1):14178.

PubMed: 30242186 ( click the link to review the publication )

Sci Rep,2018,8(1):12046

PubMed: 30104685 ( click the link to review the publication )

J Cell Physiol,2018,233(1):422-433

PubMed: 28294327 ( click the link to review the publication )

Biomed Opt Express,2018,9(5):2214-2228

PubMed: 29760982 ( click the link to review the publication )
Biochem Biophys Res Commun,2018,495(1):1468-1475

PubMed: 29196261 ( click the link to review the publication )

SLAS Discov,2018,23(2):164-173

PubMed: 28985478 ( click the link to review the publication )

Oncotarget,2018,9(57):31018-31031

PubMed: 30123424 ( click the link to review the publication )

Methods Mol Biol,2018,1795:203-221.

PubMed: 29846930 ( click the link to review the publication )

Methods Mol Biol,2018,1765:333-347

PubMed: 29589319 ( click the link to review the publication )

Oncotarget,2018,9(40):26086-26095

PubMed: 29899844 ( click the link to review the publication )

Oncotarget,2018,9(32):22571-22585

PubMed: 29854299 ( click the link to review the publication )

Nat Commun,2017,17;8:16078.

PubMed: 28714472 ( click the link to review the publication )

Proc Natl Acad Sci U S A,2017,114(36):E7554-E7563

PubMed: 28784769 ( click the link to review the publication )

Cell Rep,2017,20(4):999-1015

PubMed: 28746882 ( click the link to review the publication )

Lab Chip,2017,31;17(3):511-520.

PubMed: 28092382 ( click the link to review the publication )

J Med Chem,2017,60(7):2973-2982

PubMed: 28263602 ( click the link to review the publication )

Anal Chem,2017,89(12):6678-6685

PubMed: 28520400 ( click the link to review the publication )

Mol Cancer Ther,2017,16(12):2656-2667

PubMed: 28878027 ( click the link to review the publication )

Antimicrob Agents Chemother,2017,62(1)

PubMed: 29061736 ( click the link to review the publication )

Sci Rep,2017,7(1):14416

PubMed: 29089548 ( click the link to review the publication )

PLoS One,2017,5;12(1):e0169407.

PubMed: 28056055 ( click the link to review the publication )

SLAS Discov,2017,22(5):507-515

PubMed: 28324660 ( click the link to review the publication )

SLAS Discov,2017,22(5):484-493

PubMed: 28346106 ( click the link to review the publication )

SLAS Discov,2017,22(9):1120-1130

PubMed: 28783477 ( click the link to review the publication )

Parasitol Res,2017,116(10):2619-2626.

PubMed: 28776226 ( click the link to review the publication )

Biol Pharm Bull,2017,40(8):1289-1298.

PubMed: 28769010 ( click the link to review the publication )

PhD School in Cell Biology and Development,2017,1-76

PubMed: None ( click the link to review the publication )

Oncotarget,2017,8(43):73745-73756

PubMed: 29088741 ( click the link to review the publication )
Parasit Vectors,2017,10(1):323

PubMed: 28679424 ( click the link to review the publication )

Oncotarget,2017,8(32):53154-53167

PubMed: 28881801 ( click the link to review the publication )

Methods Cell Biol,2017,138:651-679

PubMed: 28129862 ( click the link to review the publication )

Assay Drug Dev Technol,2017,15(5):198-209

PubMed: 28723269 ( click the link to review the publication )

Oncotarget,2017,8(28):45088-45104

PubMed: 28187446 ( click the link to review the publication )

J Invest Dermatol,2016,136(10):2041-2048

PubMed: 27251789 ( click the link to review the publication )

PLoS Genet,2016,12(9):e1006279

PubMed: 27588951 ( click the link to review the publication )

ACS Infect Dis,2016,2(3):180-186

PubMed: 26998514 ( click the link to review the publication )

Pharmacol Res,2016,113(Pt A):216-227

PubMed: 27543462 ( click the link to review the publication )

J Cyst Fibros,2016,15(3):285-94

PubMed: 26694805 ( click the link to review the publication )

Biogerontology,2016,17(5-6):907-920.

PubMed: 27484416 ( click the link to review the publication )

PLoS One,2016,11(6):e0157497

PubMed: 27362433 ( click the link to review the publication )

PLoS One,2016,11(2):e0149848

PubMed: 26919709 ( click the link to review the publication )

Sensors (Basel),2016,16(3)

PubMed: 26999137 ( click the link to review the publication )

Database (Oxford),2016,7;2016:baw041.

PubMed: 27055828 ( click the link to review the publication )

Oncotarget,2016,7(48):79637-79653

PubMed: 27793034 ( click the link to review the publication )

Curr Protoc Toxicol,2016,69:9.10.1-9.10.26

PubMed: 27479365 ( click the link to review the publication )

Genome Biol,2015,19;16(1):127.

PubMed: 26084335 ( click the link to review the publication )

Clin Cancer Res,2015,21(5):1172-82

PubMed: 25549722 ( click the link to review the publication )

Cancer Res,2015,75(24):5341-54

PubMed: 26627007 ( click the link to review the publication )

Biosens Bioelectron,2015,68:699-704

PubMed: 25668591 ( click the link to review the publication )

Cancer Discov,2015,5(2):154-67.

PubMed: 25501949 ( click the link to review the publication )

Mol Cancer Ther,2015,14(5):1213-23

PubMed: 25777964 ( click the link to review the publication )

Cell Cycle,2015,14(1):109-22

PubMed: 25602521 ( click the link to review the publication )
PLoS One,2015,10(2):e0117246

PubMed: 25659151 ( click the link to review the publication )

PLoS One,2015,10(2):e0116688

PubMed: 25710482 ( click the link to review the publication )

PLoS One,2015,10(11):e0142655

PubMed: 26569102 ( click the link to review the publication )

Oncotarget,2015,6(3):1531-43

PubMed: 25605238 ( click the link to review the publication )

Head Neck,2015,37(12):1722-32

PubMed: 24986420 ( click the link to review the publication )

Assay Drug Dev Technol,2015,13(8):456-65

PubMed: 26383544 ( click the link to review the publication )

Oncotarget,2015,6(34):35247-62

PubMed: 26497213 ( click the link to review the publication )

Mol Cancer Res,2014,12(5):703-13

PubMed: 24554781 ( click the link to review the publication )

PLoS One,2014,9(9):e106784

PubMed: 25198282 ( click the link to review the publication )

Oncotarget,2014,5(15):6512-25

PubMed: 25156567 ( click the link to review the publication )

Curr Protoc Chem Biol,2014,4:177-191

PubMed: 26705509 ( click the link to review the publication )

Assay Drug Dev Technol,2014,12(9-10):514-26

PubMed: 25506801 ( click the link to review the publication )

Oncogenesis,2013,2:e69

PubMed: 24018644 ( click the link to review the publication )

Case Studies using Selleck Compound Libraries

Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):
Nature.2019;574(7777):268-272
Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):
Nat Commun. 2019 16;10(1):2197
Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):
Cell Res. 2019;29(9):739-753
Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):
Mov Disord. 2019;34(3):323-334
Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):
Blood. 2019 17;134(16):1323-1336
Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):
Cancer Immunol Res.2017;5(9):790-803

Description & Advantages

•Pyroptosis is a form of necrotic and inflammatory programmed cell death mediated by the activation of caspase-1.Pyroptosis is widely involved in the occurrence and development of infectious diseases, nervous system related diseases and atherosclerotic diseases.Recent studies have shown that pyroptosis can enhance anti-tumor immunity;

•A unique collection of 766 pyroptosis related compounds used for high throughput screening(HTS) and high content screening(HCS);

•Some compounds have been approved by the FDA;

•Structurally diverse,medicinally active,and cell permeable;

•Rich documentation with structure and bioactivity information;

•NMR and HPLC validated to ensure high purity.

Product Details

Formulation:	716 compounds pre-dissolved in 10mM DMSO, 27 compounds pre-dissolved in 10mM water, 20 compounds pre-dissolved in 2mM DMSO and 3 compounds pre-dissolved in 2mM water
Container:	96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability:	12 months -20°C in DMSO
Stability:	24 months -80°C in DMSO
Shipping:	Blue ice or dry ice

Pyroptosis Compound Library Composition

HTS Facility Partners

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A unique collection of 3010 chemical compounds featured different core structures and structural diversities respectively for high throughput screening (HTS) and high content screening (HCS).
Natural Product Library

A unique collection of 2632 natural products for high throughput screening (HTS) and high content screening (HCS).
Human Endogenous Metabolite Compound Library

1021 small collections of human endogenous metabolites, involving multiple metabolic pathways, which can be used for high-throughput screening, opening up new ways for humans to treat various diseases such as tumors.
Alkaloid Compound Library

A unique collection of 413 alkaloid compounds used for high throughput screening(HTS) and high content screening(HCS).
Angiogenesis Related compound Library

A unique collection of 409 small molecules used for angiogenesis research targeting Bcr-Abl,BTK,HIF,VEGFR,FGFR,FAK,etc.
Anti-Aging Compound Library

A unique collection of 2314 anti-aging compounds used for aging related research.
Anti-alzheimer Disease Compound Library

A unique collection of 661 small molecules for exploring the mechanism of alzheimer's disease.
Antibiotics compound Library

A unique collection of 479 antibiotics used for anti- research in order to identify drug target and open up new mechanism and ways to treat human disease.
Anti-cancer Compound Library

A unique collection of 3864 anti-cancer compounds for multiple cancers: Breast Cancer, Leukemia, Lung Cancer, Lymphoma, etc.
Anti-cancer Compound Library-Ⅱ

A unique collection of 914 compounds with anticancer activity which has been verified by broad institute,half of the compounds are non-oncology drugs.
Anti-cancer Metabolism Compound Library

A unique collection of 320 small molecules for cancer metabolism research.
Anti-Cardiovascular Disease Compound Library

A unique collection of 698 anti-cardiovascular disease related compounds used for high throughput screening(HTS) and high content screening(HCS).
Anti-diabetic Compound Library

A unique collection of 149 small molecules for exploring the development of diabetes.
Anti-infection Compound Library

A unique collection of 1396 anti-infection compounds with biological activity of antibacterial,antifungal,antiviral,etc.
Antioxidant Compound Library

A unique collection of 421 compounds used for exploring the relationship between anti-oxidation and some diseases such as aging,cancer,alzheimer's disease,parkinson's disease,diabetes,etc.
Anti-parasitic Compound Library

A unique collection of 220 anti-parasitic compounds used for high throughput screening(HTS) and high content screening(HCS).
Antiviral Compound Library

A unique collection of 701 antiviral compounds used for exploring novel antiviral drug.
Apoptosis Compound Library

A unique collection of 1235 small molecules used for apoptosis research targeting Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survivin, etc.
Autophagy Compound Library

A unique collection of 1025 small molecules with autophagy-inducing or autophagy-inhibiting activity.
Calcium Channel Blocker Library

A unique collection of 101 calcium channel blockers used for high throughput screening(HTS) and high content screening(HCS).
Cambridge Cancer Compound Library

A unique collection of 247 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS).
Carbohydrate Metabolism Compound Library

A unique collection of 551 carbohydrate metabolism related compounds used for high throughput screening(HTS) and high content screening(HCS).
Cell Cycle compound library

A unique collection of 120 small molecule compounds used for cell cycle and related diseases research.
CNS-Penetrant Compound Library

A unique collection of 734 CNS-Penetrant compounds with biological activity for neurologic research.
Covalent Inhibitor Library

A unique collection of 109 covalent Inhibitors for high throughput screening (HTS) and high content screening (HCS).
Cytokine Inhibitor Library

A unique collection of 461 cytokine inhibitors used for high throughput screening(HTS) and high content screening(HCS).
Cytoskeletal Signaling Pathway Compound Library

A unique collection of 544 compounds used for research in cytoskeleton and cytoskeletal interactions.
DNA Damage/DNA Repair compound Library

A unique collection of 685 small molecules used for DNA Damage and Repair research with targeting PARP,ATM/ATR,Topoisomerase,DNA/RNA Synthesis etc.
Drug-like Compound Library

A unique collection of 2050 drug-like compounds used for high throughput screening(HTS) and high content screening(HCS).
Endoplasmic Reticulum Stress Compound Library

A unique collection of 147 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening(HTS) and high content screening(HCS).
Epigenetics Compound Library

A unique collection of 751 compounds with biological activity used for epigenetic research and associated assays.
Exosome Secretion Related Compound Library

A unique collection of 51 exosome secretion related compounds used for high throughput screening(HTS) and high content screening(HCS).
FDA-approved Anticancer Drug Library

A unique collection of 1723 approved drugs with anticancer activity used for high throughput screening(HTS) and high content screening(HCS).
Ferroptosis Compound Library

A unique collection of 723 compounds used for exploring the mechanism of ferroptosis which is an iron-dependent form of non-apoptotic cell death.
Flavonoid Compound Library

A unique collection of 236 flavonoid compounds used for high throughput screening(HTS) and high content screening(HCS).
Fragment Library

A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD).
Glutamine Metabolism Compound Library

A unique collection of 439 glutamine metabolism related compounds used for high throughput screening (HTS) and high content screening (HCS).
Glycolysis Compound Library

A unique collection of 396 glycolysis related compounds used for high throughput screening(HTS) and high content screening(HCS).
GPCR Compound Library

A unique collection of 1325 small molecules targeting G protein coupled receptors for high throughput screening (HTS) and high content screening (HCS).
Gut Microbial Metabolite Library

A unique collection of 140 gut microbial metabolites used for high throughput screening(HTS) and high content screening(HCS).
HIF-1 Signaling Pathway Compound Library

A unique collection of 444 HIF-1 signaling pathway compounds used for oxygen sensing related research.
Highly Selective Inhibitor Library

A unique collection of 462 validated highly selective inhibitors with covering over 123 targets.
Histone modification compound library

A unique collection of 245 small molecule compounds with biological activity used for histone modification research and associated assays.
HTS Library for Drug Discovery

A unique collection of 99040 compounds features numerous structurally diverse compounds and several alternate compositions.
Human Hormone Related Compound Library

A unique collection of 478 human hormone related compounds used for high throughput screening(HTS) and high content screening(HCS).
Human Transcription Factor Compound Library

A unique collection of 385 human transcription factor related compounds used for high throughput screening(HTS) and high content screening(HCS).
Immunology/Inflammation Compound Library

A unique collection of 2775 small molecules with biological activity used for Immunology/Inflammation research and associated assays.
Inhibitor Library

A unique collection of 4156 inhibitors for high throughput screening (HTS) and high content screening (HCS).
Ion Channel Ligand Library

A unique collection of 224 small molecule modulators used for Ion channel research.
JAK/STAT compound library

A unique collection of 191 small molecules used for research in JAK-STAT signaling pathway.
Lipid Metabolism Compound Library

A unique collection of 410 lipid metabolism related compounds used for high throughput screening(HTS) and high content screening(HCS).
Macrocyclic Compound Library

A unique collection of 188 macrocyclic compounds used for high throughput screening(HTS) and high content screening(HCS).
MAPK Inhibitor Library

A unique collection of 259 small molecule inhibitors used for MAPK signaling research.
Medicine Food Homology Compound Library

A unique collection of 486 medicine food homology compounds used for high throughput screening (HTS) and high content screening (HCS).
Metabolism Compound Library

A unique collection of 2854 small molecules with biological activity in numerous metabolic pathway: glycometabolism, lipid metabolism, proteolysis, etc.
Methylation Compound Library

A unique collection of 112 compounds used for researching the function of methylation in epigenetics,cancer,embryogenesis,etc.
Mouse Metabolite Compound Library

A unique collection of 163 mouse metabolites used for high throughput screening(HTS) and high content screening(HCS).
Natural Organic Compound Library

A unique collection of 1106 plant-derived natural organic compounds used for high throughput screening(HTS) and high content screening(HCS).
Neuronal Signaling Compound Library

A unique collection of 1372 small molecule compounds with biological activity used for neurologic research and associated assays
NF-κB Signaling Compound Library

A unique collection of 428 small molecules used for NF-κB signaling pathway research which plays a key role in immunology/inflammation and cancer.
Nucleoside Analogue Library

A unique collection of 195 nucleoside analogues used for high throughput screening(HTS) and high content screening(HCS).
Obesity Compound Library

A unique collection of 930 compounds used for research in obesity.
Oxidative Stress Compound Library

A unique collection of 1445 oxidative stress related compounds used for high throughput screening(HTS) and high content screening(HCS).
Phenotypic Screening Library

A unique collection of 3733 bioactive compounds with identified targets used for phenotypic Screening.
PI3K/Akt Inhibitor Library

A unique collection of 350 small molecule inhibitors used for PI3K/Akt/mTOR pathway research.
Protease Inhibitor Library

A unique collection of 383 small molecule inhibitors used for chemical genomics, high-throughput screening (HTS), and high content screening (HCS).
Protein-protein Interaction Inhibitor Library

A unique collection of 188 protein-protein Interaction(PPI) Inhibitors used for high throughput screening(HTS) and high content screening(HCS).
Small Molecule Immuno-Oncology Compound Library

A unique collection of 248 Immuno-Oncology small molecules used for oncotherapy in conjunction with other drugs.
Stem Cell Differentation Compound Library

A unique collection of 250 stem cell differentation related compounds used for high throughput screening(HTS) and high content screening(HCS).
Stem Cell Signaling Compound Library

A unique collection of 870 compounds with biological activity used for stem cell regulatory and signaling pathway research.
TGF-beta/Smad compound library

A unique collection of 135 small molecules with biological activity used for TGF-beta/Smad pathway research.
Traditional Chinese Medicine Library

A unique collection of 1444 traditional chinese medicine(TCM) monomer compounds used for high throughput screening(HTS) and high content screening(HCS).
Tyrosine Kinase Inhibitor Library

A unique collection of 533 tyrosine kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).
Ubiquitination Compound Library

A unique collection of 198 small molecules for Ubiquitination related research.

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