Home DNA Damage/DNA Repair DNA/RNA Synthesis Chemical L-Asparaginase

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L-Asparaginase DNA/RNA Synthesis Chemical

Cat.No.E8190

L-Asparaginase(L-ASNase) is a deamidating enzyme that hydrolyzes L-asparagine and L-glutamine, depleting L-asparagine in the blood and bone marrow. It exhibits anti-leukemic effects by inhibiting RNA and DNA synthesis, leading to blastic cell apoptosis, and is used in acute lymphoblastic leukemia (ALL) research and treatment.
L-Asparaginase DNA/RNA Synthesis Chemical Chemical Structure

Chemical Structure

Molecular Weight: 34.5KDa

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Chemical Information, Storage & Stability

Molecular Weight 34.5KDa Formula Storage (From the date of receipt) 2 years 4°C, in dark and seal
CAS No. 9015-68-3 -- Storage of Stock Solutions

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

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