research use only

LSKL, Inhibitor of Thrombospondin (TSP-1)

Cat.No.P1164

LSKL, Inhibitor of Thrombospondin (TSP-1), a small molecular peptide and competitive antagonist for transforming growth factor-β1 (TGF-β1), protects against subarachnoid fibrosis and hydrocephalus after subarachnoid hemorrhage (SAH).

Amino-acid Sequence

CAS No. 283609-79-0

Quality Control

Batch: P116401 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] 100 mg/mL] false Purity: 99.94%

99.94

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL (218.05 mM)；
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 100 mg/mL

Ethanol : 100 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Biological Activity

Description	LSKL, Inhibitor of Thrombospondin (TSP-1), a small molecular peptide and competitive antagonist for transforming growth factor-β1 (TGF-β1), protects against subarachnoid fibrosis and hydrocephalus after subarachnoid hemorrhage (SAH).
Targets/IC₅₀/Ki	TGF-β1

References
https://pubmed.ncbi.nlm.nih.gov/27698755/

References

https://pubmed.ncbi.nlm.nih.gov/27698755/

Product Information

Molecular Formula	C₂₁H₄₂N₆O₅
Molecular Weight	458.6
CAS No.	283609-79-0
Appearance	White Powder
Peptide Content (by %N)	≥80%
Single Impurity (by HPLC)	≤1.0%
Assay (By Anhydrous, Acetic Acid-free)	95.0~105.0%
MS	Consistent
Packing	plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage (From the date of receipt)	3 years-20°C powder
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)