Home Biosimilar Antibodies Others Antibody-Drug Conjugate inhibitor Ladiratuzumab vedotin
For research use only. Not for use in humans.

Ladiratuzumab vedotin

Synonyms: SGN-LIV1A, Anti-LIV-1 ADC

Ladiratuzumab vedotin (SGN-LIV1A, Anti-LIV-1 ADC) is an antibody-drug conjugate (ADC) composed of humanized anti-LIV-1 antibody, conjugated to Monomethyl auristatin E (MMAE), via a proteolytically cleavable type linker. Ladiratuzumab vedotin has the potential for use in multiple carcinomas.

Ladiratuzumab vedotin

CAS No.

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Quality Control

Batch: D405701 Purity: 99.15% Protein concentration: 3.21mg/ml Endotoxin Level: ＜1EU/mg
99.15

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Ladiratuzumab vedotin (SGN-LIV1A, Anti-LIV-1 ADC) is an antibody-drug conjugate (ADC) composed of humanized anti-LIV-1 antibody, conjugated to Monomethyl auristatin E (MMAE), via a proteolytically cleavable type linker. Ladiratuzumab vedotin has the potential for use in multiple carcinomas.
References

Product Details

DAR 4.16
ADC antiody ladiratuzumab
ADC linker A proteolytically cleavable type linker
ADC cytotoxin MMAE
Formulation 1xPBS
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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