α-L-Rhamnose monohydrate

Catalog No.S3887 Synonyms: 6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate

For research use only.

α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate) is used as a starting material for the production of furanones. It is an important material involved in the reaction of flavors developed during the preparation of various foods like bread, grilled meats, etc.

α-L-Rhamnose monohydrate Chemical Structure

CAS No. 6155-35-7

Purity & Quality Control

Related Other Products

Biological Activity

Description α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate) is used as a starting material for the production of furanones. It is an important material involved in the reaction of flavors developed during the preparation of various foods like bread, grilled meats, etc.
In vitro

L-rhamnose in concentration up to 20 (32 resp.) mmol/l can not be considered as cytotoxic or cytostatic for the used in vitro tumor models[1].

In vivo L-rhamnose exerts a significant suppressive effect on tumour growth. Its optimal dose is estimated to be 3.64 g/kg/day[2].

Protocol (from reference)

Cell Research:[1]
  • Cell lines: HL-60 cells
  • Concentrations: 0.125 mmol/l to 32 mmol/l
  • Incubation Time: 48 h
  • Method: At the beginning of the experiment, HL-60 cells are diluted to a concentration of 2x105/ml. Exponential growth of control cells is apparent during the observation interval. HL-60 cells are exposed to L-rhamnose or 2-deoxyglucose in final concentration from 0.125 mmol/l to 32 or 16 mmol/l, resp., in full cultivating medium.
  • (Only for Reference)
Animal Research:[2]
  • Animal Models: NMRI female mice
  • Dosages: 1, 3, or 5 g/kg/day
  • Administration: i.p.
  • (Only for Reference)

Solubility (25°C)

In vitro

DMSO 36 mg/mL
(197.61 mM)


* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 182.17
Formula

C6H12O5.H2O

CAS No. 6155-35-7
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1C(C(C(C(O1)O)O)O)O.O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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