Highly Selective Inhibitor Library

Catalog No.L3500

Offered in 96 or 384 well plate format

A unique collection of 462 validated highly selective inhibitors with covering over 123 targets.

Selleck Chemicals compound library contributes and expedites
the investigation of treatments against COVID19

The researchers at the National Institute of Infectious Diseases, in Japan, successfully found anti-COVID19 drugs within 3 months of
screening FDA-approved drug library from Selleck Chemicals. They have already published this article doi: 10.1101/2020.04.14.039925.

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Highly Selective Inhibitor Library Contents

Cited by 212 Publications

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer
  • Application of Kinase Inhibitor Library in colorectal cancer
    Nat Commun. 2019 16;10(1):2197
  • Application of FDA-approved Drug Library in antivirus
    Cell Res. 2019;29(9):739-753
  • Application of FDA-approved Drug Library in metabolism
    Mov Disord. 2019;34(3):323-334
  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia
    Blood. 2019 17;134(16):1323-1336
  • Application of Inhibitor Library in tumor immunology
    Cancer Immunol Res.2017;5(9):790-803

Description & Advantages

• A unique collection of 462 validated highly selective inhibitors with covering over 123 targets

• Selectivity is at least 100-fold higher relative to non-primary target(s)

• Each compound was selected based on its ability to principally interact with a single target, leading to minimal off-target activity

•Targets cover a wide variety of signaling pathways, including PI3K/Akt, MAPK, PTK, JAK, apoptosis, and others!

• This unique tool is ideal for studying mechanisms of action or for target screening

• Compounds are structurally diverse, biologically active, and cell permeable

• Selleck provides rich supporting documentation which includes compound structure and customer reviews

• Compounds are NMR and HPLC validated to ensure our customers receive high purity compounds

Product Details

Formulation: 432 compounds pre-dissolved in 10mM DMSO, 7 compounds pre-dissolved in 10mM water and 23 compounds pre-dissolved in 2mM DMSO
Container: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability: in DMSO
Shipping: Blue ice or dry ice

Highly Selective Inhibitor Library Composition

HTS Facility Partners

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