Highly Selective Inhibitor Library

Catalog No.L3500

Offered in 96 or 384 well plate format

A unique collection of 474 validated highly selective inhibitors with covering over 123 targets.

96 well box

Customize Your Library:

Cited by 247 Publications

Description & Advantages

• A unique collection of 474 validated highly selective inhibitors with covering over 123 targets

• Selectivity is at least 100-fold higher relative to non-primary target(s)

• Each compound was selected based on its ability to principally interact with a single target, leading to minimal off-target activity

•Targets cover a wide variety of signaling pathways, including PI3K/Akt, MAPK, PTK, JAK, apoptosis, and others!

• This unique tool is ideal for studying mechanisms of action or for target screening

• Compounds are structurally diverse, biologically active, and cell permeable

• Selleck provides rich supporting documentation which includes compound structure and customer reviews

• Compounds are NMR and HPLC validated to ensure our customers receive high purity compounds

Product Details
Formulation 444 compounds pre-dissolved in 10mM DMSO, 7 compounds pre-dissolved in 10mM water and 23 compounds pre-dissolved in 2mM DMSO
Container 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability 12 months -20°C in DMSO
24 months -80°C in DMSO
Shipping Blue ice or dry ice
Case Studies using Selleck Compound Libraries
  • Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

    Nature.2019;574(7777):268-272

  • Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

    Nat Commun. 2019 16;10(1):2197

  • Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

    Cell Res. 2019;29(9):739-753

  • Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

    Mov Disord. 2019;34(3):323-334

  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

    Blood. 2019 17;134(16):1323-1336

  • Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

    Cancer Immunol Res.2017;5(9):790-803

Highly Selective Inhibitor Library Composition

HTS Facility Partners