research use only

Levoglucosan

Cat.No.S3319

Levoglucosan (LG, LEV, Leucoglucosan, Glucosan, 1,6-anhydro-b-D-Glucose) is an endogenous metabolite.

Chemical Structure

Molecular Weight: 162.14

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S331901 DMSO]32 mg/mL]false]Water]32 mg/mL]false]Ethanol]32 mg/mL]false Purity: 99.17%

99.17

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Chemical Information, Storage & Stability

Molecular Weight	162.14	Formula	C₆H₁₀O₅	Storage (From the date of receipt)	3 years -20°C powder
CAS No.	498-07-7	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	LG, LEV, Leucoglucosan, Glucosan, 1,6-anhydro-b-D-Glucose			Smiles	OC1C(O)C2COC(O2)C1O

Solubility

In vitro
Batch:

DMSO : 32 mg/mL ( (197.36 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 32 mg/mL

Ethanol : 32 mg/mL

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
=	×	×

Dilution Calculator Molecular Weight Calculator

In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT06404632	Recruiting	Life Style\|Health-Related Behavior\|Disabilities Mental\|Disability Physical\|Acceptability of Health Care	Region Stockholm\|Karolinska Institutet\|Promobilia Foundation	April 12 2024	Not Applicable
NCT06372301	Recruiting	Transthyretin Amyloid Cardiomyopathy\|Aortic Stenosis	Steen Hvitfeldt Poulsen\|Aarhus University Hospital Skejby	April 2 2024	Not Applicable
NCT04941599	Recruiting	Familial Hypercholesterolemia	Vanderbilt University Medical Center\|National Heart Lung and Blood Institute (NHLBI)	February 14 2024	Phase 2
NCT06130787	Recruiting	LeukemiaMyeloid Chronic	University Hospital Clermont-Ferrand	November 17 2023	Not Applicable
NCT06040164	Not yet recruiting	PreDiabetes\|Diabetes Mellitus Type 2\|Obesity\|Oral Dysbiosis\|Mouth Disease	Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud	October 1 2023	--

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
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C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):