InVivo Antibodies

Catalog No. Product Name Information Application Clone
A2102New Anti-mouse CD8α-InVivo Anti-mouse CD8α reacts with mouse CD8α. CD8 is a transmembrane glycoprotein that acts as a co-receptor for the T cell receptor (TCR). It binds to class I MHC molecules displayed by antigen presenting cells (APC). In vivo CD8+ T cell depletion,WB 2.43
A2120New Anti-mouse IL-17A-InVivo Anti-mouse IL-17A-InVivo monoclonal antibody (Clone:17F3) reacts with mouse IL-17A which is a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. Anti-mouse IL-17A-InVivo has been shown to neutralize IL-17A in vivo. in vivo IL-17A neutralization 17F3
A2121New Anti-mouse IFNAR-1-InVivo Anti-mouse IFNAR-1-InVivo monoclonal antibody (Clone: MAR1-5A3) reacts with mouse IFNAR-1 (IFN alpha/beta receptor subunit 1). Anti-mouse IFNAR-1-InVivo has been shown to inhibit Type I IFN receptor signaling in vitro and in vivo. in vivo IFNAR-1 blockade, in vitro IFNAR-1 blockade, WB MAR1-5A3
A2116New Rat IgG2b isotype control-InVivo Rat IgG2b isotype control-InVivo monoclonal antibody (Clone:LTF-2) reacts with keyhole limpet hemocyanin (KLH). Because KLH is not expressed by mammals this antibody is ideal for use as an isotype-matched control for rat IgG2b antibodies in most in vivo and in vitro applications. LTF-2
A2119New Rat IgG1 isotype control-InVivo Rat IgG1 isotype control-InVivo monoclonal antibody (Clone:HRPN) reacts with horseradish peroxidase (HRP). Because HRP is not expressed by mammals this antibody is ideal for use as an isotype-matched control for rat IgG1 antibodies in most in vivo and in vitro applications. HRPN
A2118New Anti-mouse IL-6-InVivo Anti-mouse IL-6-InVivo monoclonal antibody (Clone:MP5-20F3) can reacts with mouse IL-6 (interleukin-6) which is a 21-28 kDa cytokine that is expressed by many cell types, including T lymphocytes, B lymphocytes, monocytes, fibroblasts, and endothelial cells. Anti-mouse IL-6-InVivo has been shown to neutralize the bioactivity of natural or recombinant IL-6. in vivo IL-6 neutralization MP5-20F3
A2115New Anti-mouse PD-L1 (B7-H1)-InVivo Anti-mouse PD-L1 (B7-H1)-InVivo (Clone:10F.9G2) monoclonal antibody reacts with mouse PD-L1 (also known as B7-H1, CD274). The 10F.9G2 antibody has been shown to block the interaction between PD-L1 and PD-1 and between PD-L1 and B7-1 (CD80). in vivo PD-L1 blockade,IHC (frozen),FCM 10F.9G2
A2117New Mouse IgG2a isotype control-InVivo Mouse IgG2a isotype control-InVivo (Clone:C1.18.4) monoclonal antibody is ideal for use as a non-reactive isotype-matched control for mouse IgG2a antibodies in most in vivo and in vitro applications. C1.18.4
A2101 Anti-mouse CD4-InVivo Anti-mouse CD4 antibody reacts with mouse CD4, which is a 55 kDa cell surface type I membrane glycoprotein. CD4 is a co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells. In vivo CD4+ T cell depletion,FCM,WB GK1.5
A2105 Anti-mouse IFNγ-InVivo The R4-6A2 monoclonal antibody reacts with mouse IFNγ (interferon gamma) which is a 20 kDa soluble pleiotropic cytokine and the sole member of the type II class of interferons. The R4-6A2 antibody has been shown to neutralize both natural and recombinant IFNγ. in vivo/vitro IFNγ neutralization R4-6A2
A2107 Anti-mouse CD25 (IL-2Rα)-InVivo The PC-61.5.3 monoclonal antibody reacts with mouse IL-2Rα also known as CD25, Ly-43, p55, or Tac.The PC-61.5.3 antibody has been shown to inhibit the binding of IL-2 to both the low and high affinity IL-2 receptor forms. Additionally, the PC-61.5.3 antibody is commonly used to deplete CD4+FoxP3+ T regulatory cells in vivo. in vivo regulatory T cell depletion,FCM PC-61.5.3
A2110 Anti-mouse CD16/CD32-InVivo The 2.4G2 monoclonal antibody reacts specifically with mouse CD16 (FcγRIII) and CD32 (FcγRII). It has also been reported to react non-specifically via its Fc domain to FcγRI. The 2.4G2 antibody is commonly used in flow cytometry staining experiments to prevent non-specific binding of IgG to the FcγIII and FcγII, and possibly FcγI, receptors prior to staining with antigen specific primary antibodies. in vitro/vivo Fc receptor blocking 2.4G2
A2103New Anti-mouse CTLA-4 (CD152)-InVivo The UC10-4F10-11 monoclonal antibody reacts with mouse CTLA-4 (cytotoxic T lymphocyte antigen-4) also known as CD152. The UC10-4F10-11 antibody has been shown to promote T cell co-stimulation by blocking CTLA-4 binding to the B7 co-receptors, allowing for CD28 binding. in vivo/vitro CTLA-4 neutralization, FCM,WB UC10-4F10-11
A2104New Anti-mouse CD3ε-InVivo The 145-2C11 monoclonal antibody reacts with mouse CD3ε which is a 20 kDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The 145-2C11 antibody has been shown to induce T lymphocyte activation, proliferation, and apoptosis in vitro via binding and stimulating the TCR. When used in vivo the antibody is reported to produce T cell activation, anergy, or death. in vitro T cell stimulation/activation, IF, FCM, WB 145-2C11
A2114 Anti-mouse NK1.1-InVivo The PK136 monoclonal antibody reacts with mouse NK1.1 also known as CD161b/CD161c, KLRB1, NKR-P1A and Ly-55. in vivo NK cell depletion,FCM PK136
A2108New Anti-mouse CD28-InVivo The PV-1 monoclonal antibody reacts with mouse CD28.The PV-1 antibody has been shown to stimulate the proliferation and cytokine production by activated T and NK cells. in vitro T cell stimulation/activation PV-1
A2109New Anti-mouse IL-4-InVivo The 11B11 monoclonal antibody reacts with mouse IL-4 (interleukin-4) which is a multifunctional 14 kDa cytokine.The 11B11 monoclonal antibody has been shown to neutralize the bioactivity of natural or recombinant IL-4. in vivo/vitro IL-4 neutralization,FCM,WB 11B11
A2113 Anti-human/mouse TGF-β-InVivo The 1D11.16.8 monoclonal antibody reacts with mouse, human, rat, monkey, hamster, canine and bovine TGF-β (transforming growth factor beta) isoforms 1, 2 and 3.The 1D11.16.8 monoclonal antibody is a neutralizing antibody. in vivo/vitro TGFβ neutralization,WB 1D11.16.8