Home PI3K/Akt/mTOR PI3K modulator α-Linolenic acid

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α-Linolenic acid PI3K modulator

Cat.No.E2391

α-Linolenic acid, an essential fatty acid isolated from seed oils, affects the process of thrombotic through the modulation of PI3K/Akt signaling, and possesses the anti-arrhythmic properties.
α-Linolenic acid PI3K modulator Chemical Structure

Chemical Structure

Molecular Weight: 278.43

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Quality Control

Batch: E239101 Purity: 98.33%
98.33

Solubility

In vitro
Batch:

DMSO : 100 mg/mL (359.15 mM) Warmed with 60°C water bath; Ultrasonicated;
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 100 mg/mL (超声加热五分钟，水浴60℃)

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Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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%
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 278.43 Formula

C18H30O2

 Storage (From the date of receipt) 2 years -20°C liquid
CAS No. 463-40-1 --

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

Targets/IC50/Ki
PI3K
Akt

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-02-06)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07392723 RECRUITING
Cognitive Dysfunction; Alzheimer Disease; Blood-Brain Barrier; Apolipoprotein E, Deficiency or Defect of; Brain Aging; Fatty Acids, Omega-3
Michal Schnaider Beeri, Ph.D.
 2025-01-12 PHASE2
NCT06274788 Not yet recruiting
Parenteral Nutrition Associated Liver Disease (PNALD)|Essential Fatty Acid Deficiency|Malnutrition|Pediatric ALL
Fresenius Kabi
 2024-05-01 Phase 4
NCT05053347 COMPLETED
Elevated Blood Sugar
Huazhong University of Science and Technology
 2022-07-01
NCT04481724 COMPLETED
Weight Trajectory
Virta Health
 2020-07-22
NCT03040856 WITHDRAWN
Omega 3 Supplements During Pregnancy
Sheba Medical Center
 2022-02-01
NCT02433977 COMPLETED
Asthma
Gladwin, Mark, MD
 2015-09 PHASE2

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