research use only

L-Ascorbyl 6-palmitate

Name: L-Ascorbyl 6-palmitate
Brand: Selleck Chemicals
SKU: S2532
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.S2532

L-Ascorbyl 6-palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C.

Chemical Structure

Molecular Weight: 414.53

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S253201 DMSO]83 mg/mL]false]Ethanol]83 mg/mL]false]Water]Insoluble]false Purity: 100%

100

Related Targets	Dyes Antineoplastic and Immunosuppressive Antibiotics ADC Cytotoxin Selection Antibiotics for Transfected Cell PROTAC Antibiotics for Mammalian Cell Culture ADC Linker Antibiotics for Plant Cell Culture PROTAC Linker Hydrotropic Agents Antibody-Drug Conjugate E3 ligase Ligand Target Protein Ligand Molecular Glues Enzyme Substrate Drug-Linker Conjugates for ADC Chelating Agent
Related Products	BAPTA-AM Rat IgG2b isotype control-InVivo Blebbistatin Methyl-β-cyclodextrin (MβCD) AP-III-a4 (ENOblock) Carbazochrome sodium sulfonate (AC-17) Ursolic Acid Osthole 4-Methylumbelliferone (4-MU) Dioscin Ethidium bromide Pitstop 2 Sesamin Bilobalide Formononetin Hesperidin Azeliragon (TTP488) L-Mimosine Carbenoxolone Sodium Vitexin N6022 Dp44mT Chlorogenic Acid Sphingosine Chrysin Coenzyme Q10 (CoQ10) Spermine Tetrahydrochloride 2-NBDG D-Lin-MC3-DMA (MC3) Morin Hydrate

Chemical Information, Storage & Stability

Molecular Weight	414.53	Formula	C₂₂H₃₈O₇	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	137-66-6	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	N/A			Smiles	CCCCCCCCCCCCCCCC(=O)OCC(C1C(=C(C(=O)O1)O)O)O

Solubility

In vitro
Batch:

DMSO : 83 mg/mL ( (200.22 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 83 mg/mL

Water : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
=	×	×

Dilution Calculator Molecular Weight Calculator

In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

In vitro	L-Ascorbyl 6-palmitate is a synthetic lipophilic ascorbic acid derivative. This compound is an effective preservative in foods and an effective dietary antitumor promoter in mice. Studies indicate that dietary this chemical is a source of tissue vitamin C in animals. Besides, dietary it possesses weak antiscorbutic activity in guinea pigs and enhances vitamin C nutriture in humans. ^[1]
In vivo	In a study, daily mean weight loss during repletion in control animals receiving placebo is significantly greater than that for L-Ascorbyl 6-palmitate animals for days 3–10 of repletion. Daily mean weight loss for this compound animals is significantly greater than that for L-ascorbic acid (AA) animals on days 5 and 6 of repletion. By comparing areas of the weight-time curve during repletion, this compound appeares to be about 50% as effective as L-ascorbic acid (AA) in reversing scurvy. ^[2]
References	http://www.sciencedirect.com/science/article/pii/S027153170580226X https://pubmed.ncbi.nlm.nih.gov/3188040/

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):