Luminespib (AUY-922, NVP-AUY922)

Catalog No.S1069 Synonyms: VER-52296

Luminespib (AUY-922, NVP-AUY922) Chemical Structure

Molecular Weight(MW): 465.54

Luminespib (AUY-922, NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Phase 2.

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In DMSO USD 320 In stock
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Cited by 24 Publications

3 Customer Reviews

  • U2OS_exo cells were incubated with AUY922 for 20 h at the indicated concentrations before stimulation with TNFα (30 ng/mL) for 30 min and immunostaining to detect NF-κB (p65). DMSO 1%, cells stimulated by TNFα in the absence of AUY922. Representative pictures used to quantify nuclear and cytoplasmic localization of NF-κB.

    Proc Natl Acad Sci USA, 2014, 111(15): E1528–37 . Luminespib (AUY-922, NVP-AUY922) purchased from Selleck.

    J Biol Chem 2013 288(23), 16308-20. Luminespib (AUY-922, NVP-AUY922) purchased from Selleck.

  • Western blots show the molecular signature of HSP90 inhibition by NVP-AUY922  (ie, induction of HSP72 and depletion of client proteins such as ERBB2, CRAF and CDK4) in BT474 breast cancer cell line. GAPDH was used as loading control.

     

     

    2011 Dr. Swee Sharp and Professor Paul Workman from Cancer Research UK. Luminespib (AUY-922, NVP-AUY922) purchased from Selleck.

Purity & Quality Control

Choose Selective HSP (e.g. HSP90) Inhibitors

Biological Activity

Description Luminespib (AUY-922, NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Phase 2.
Targets
HSP90α [1]
(Cell-free assay)
HSP90β [1]
(Cell-free assay)
13 nM 21 nM
In vitro

NVP-AUY922 inhibits proliferation of various human cancer cell lines in vitro, with an average GI50 of 9 nM. [1] The IC50 values of NVP-AUY922 fall in the range of 2 to 40 nM in these gastric cancer cell lines. IC50 value for the BEAS-2B cells is 28.49 nM. Treatment with NVP-AUY922 does not influence the expression of HSP90, but expression of HSP70 gets elevated by NVP-AUY922 treatment. NVP-AUY922 increases the binding of HSP70 to HSP90. NVP-AUY922 causes p23 dissociation from the HSP90 complex and can then recruit HSP70 to the HSP90 complex. [1] After the treatment with NVP-AUY922, expression of receptor tyrosine kinases including VEGFR1, 2, 3 and PDGFRɑ is decreased. A decrease is also noticed in the expression of Akt and phospho-Akt. Meanwhile, treatment with NVP-AUY922 causes decreased expression of HER-2 in NCI-N87 cells. NVP-AUY922 treatment results in binding of HSP90 to client proteins and setting them up as targets for degradation by the proteasome. NVP-AUY922 can influence cell growth by affecting multiple signaling pathways. In addition, treatment with the proteasome inhibitor, MG132, restores expression of thymidylate synthase, which is decreased by NVP-AUY922. NVP-AUY922 increases the expression of cleaved caspase-3 leading to apoptosis in HSC-2 cells.[1]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
CMK M2m1Wmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYDTTo5KUUN3ME2wMlAxODF{NTFOwG0> M4fWSHNCVkeHUh?=
MV-4-11 MkDWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4G2cWlEPTB;MD6wNFA2PThizszN MUPTRW5ITVJ?
NALM-6 M3y3cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYmybYJYUUN3ME2wMlAxODh2MjFOwG0> NIPxV|RUSU6JRWK=
HOS NHXsVpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVzJR|UxRTBwMECxN|gh|ryP MnvIV2FPT0WU
HT-144 NX3iclhmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU\ZXJdpUUN3ME2wMlAxOTV3IN88US=> NH3IcllUSU6JRWK=
SW1710 MoG0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTBwMECxPFYh|ryP M3nROnNCVkeHUh?=
TE-8 Mn\JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWLxOm56UUN3ME2wMlAxOjN5IN88US=> NW[xSXBoW0GQR1XS
ES1 MonuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkfwTWM2OD1yLkCwNlY3KM7:TR?= MmfaV2FPT0WU
CCF-STTG1 M3PId2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVXzTIRrUUN3ME2wMlAxOjl5IN88US=> M2XUO3NCVkeHUh?=
PSN1 MmW4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxRTBwMECzNVgh|ryP M3rE[XNCVkeHUh?=
CAL-51 NEP2OlJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4fwfGlEPTB;MD6wNFMzPSEQvF2= M2TPfXNCVkeHUh?=
MCF7 NU\vS3lNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{HtcGlEPTB;MD6wNFM{PSEQvF2= NWO1cIxZW0GQR1XS
SK-HEP-1 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWPJR|UxRTBwMECzN|Yh|ryP NH\vVXhUSU6JRWK=
LCLC-103H MlrBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVL6eYs4UUN3ME2wMlAxPDNizszN M3rJ[HNCVkeHUh?=
HMV-II M3vKfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1HqVWlEPTB;MD6wNFQ1QSEQvF2= MmXGV2FPT0WU
MES-SA M1TRUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MljYTWM2OD1yLkCwOFUzKM7:TR?= MXfTRW5ITVJ?
SK-LMS-1 NGTOXJNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2\nb2lEPTB;MD6wNFQ2QCEQvF2= NF;GT4pUSU6JRWK=
639-V M3rUZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm[1TWM2OD1yLkCwOFg2KM7:TR?= MVzTRW5ITVJ?
SIG-M5 NGLvZ2VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXvJR|UxRTBwMEC0PFkh|ryP NHHtfHNUSU6JRWK=
LOUCY MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NI\kb49KSzVyPUCuNFA2ODVizszN MWTTRW5ITVJ?
HSC-2 M{X6Vmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4XqeWlEPTB;MD6wNFUyQCEQvF2= MnLmV2FPT0WU
EW-13 MkLNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUC3NFkzUUN3ME2wMlAxPTF6IN88US=> NYLsZYVvW0GQR1XS
RT-112 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MniwTWM2OD1yLkCwOVM2KM7:TR?= NIqyfWZUSU6JRWK=
NKM-1 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYW5dWE6UUN3ME2wMlAxPTR5IN88US=> M2m4OHNCVkeHUh?=
KYSE-180 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3nUVmlEPTB;MD6wNFU5PiEQvF2= NGnBOINUSU6JRWK=
SW1783 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV7JR|UxRTBwMEC1PVEh|ryP M3PyNXNCVkeHUh?=
A431 NITySohIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn2zTWM2OD1yLkCwOlA4KM7:TR?= MVLTRW5ITVJ?
SK-OV-3 M4O1fmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{f4d2lEPTB;MD6wNFY{KM7:TR?= MlroV2FPT0WU
RPMI-7951 NHPK[YpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXjMRoM6UUN3ME2wMlAxPjNzIN88US=> MUXTRW5ITVJ?
Capan-2 NXLRSoxFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1y3eWlEPTB;MD6wNFY{QCEQvF2= M3LzOHNCVkeHUh?=
HSC-3 NVXidYx1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnewTWM2OD1yLkCwOlQyKM7:TR?= NV7tWnNVW0GQR1XS
786-0 MnPxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxRTBwMEC2OlMh|ryP NUT3dHVZW0GQR1XS
Daoy NVj1OIZKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{Tpd2lEPTB;MD6wNFY6PSEQvF2= NXf1PZJ4W0GQR1XS
KGN M3jKfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1TObWlEPTB;MD6wNFcxOyEQvF2= M2rDTHNCVkeHUh?=
EW-16 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml\tTWM2OD1yLkCwO|Q6KM7:TR?= NUXyeYM3W0GQR1XS
EW-7 MmTiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlTtTWM2OD1yLkCwO|U1KM7:TR?= NYX4N2hZW0GQR1XS
IGROV-1 NXHrbmRWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYfKbnp[UUN3ME2wMlAxQDF2IN88US=> NIHqV3NUSU6JRWK=
8505C MoXuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEX3OHVKSzVyPUCuNFA5OjFizszN M1rmNnNCVkeHUh?=
RKO NUPsO49xT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXPrRnU{UUN3ME2wMlAxQDJ4IN88US=> NX[1WZRTW0GQR1XS
GDM-1 NYXYe2c1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHrkZ2pKSzVyPUCuNFA5PCEQvF2= NXzrRWZIW0GQR1XS
IST-MEL1 M3jyVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWrwRmlnUUN3ME2wMlAxQDV{IN88US=> Mk\1V2FPT0WU
RPMI-6666 MmnLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3iwPWlEPTB;MD6wNFg2OiEQvF2= NFvP[YtUSU6JRWK=
SNG-M NYHl[HdzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFvFUGJKSzVyPUCuNFA5PTZizszN M3TiOXNCVkeHUh?=
KS-1 Ml7hS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MW\JR|UxRTBwMEC4OVkh|ryP MnPxV2FPT0WU
RXF393 NXfZenl2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmjlTWM2OD1yLkCwPFYh|ryP M4XtVXNCVkeHUh?=
CAL-12T NFLObHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mk\mTWM2OD1yLkCwPVIzKM7:TR?= M4DWeXNCVkeHUh?=
BFTC-905 MoDYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFfDbFhKSzVyPUCuNFA6OzhizszN M4\IRXNCVkeHUh?=
SK-MES-1 NYjVdJpCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkK1TWM2OD1yLkCwPVQ2KM7:TR?= M{H1UnNCVkeHUh?=
BB30-HNC NXjMcYt4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHPyT29KSzVyPUCuNFA6PTJizszN NHPWfm9USU6JRWK=
AN3-CA NXLYTHhmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYX6VW9CUUN3ME2wMlAyODF5IN88US=> MmTTV2FPT0WU
EFO-27 M4LnNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYWxPVFQUUN3ME2wMlAyODF5IN88US=> MXzTRW5ITVJ?
G-401 NG\jSJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mnv6TWM2OD1yLkCxNFI2KM7:TR?= NXu5UYRQW0GQR1XS
BPH-1 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWPJR|UxRTBwMEGwN{DPxE1? NYP1RYVJW0GQR1XS
NCI-H727 MkSxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHvuNFdKSzVyPUCuNFExOyEQvF2= MnfyV2FPT0WU
SNU-423 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXLOUYFOUUN3ME2wMlAyODV|IN88US=> NHzieZNUSU6JRWK=
KYSE-270 NELtS2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml7KTWM2OD1yLkCxNFU6KM7:TR?= M4K5S3NCVkeHUh?=
AGS NFjscIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYf6XpZ5UUN3ME2wMlAyODZzIN88US=> NVL1b2NwW0GQR1XS
NCI-H2228 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUfJR|UxRTBwMEGwOlQh|ryP MXTTRW5ITVJ?
SW954 M4KxbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mo[2TWM2OD1yLkCxNFcyKM7:TR?= NYX6O5lGW0GQR1XS
769-P NVOyVIRHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHXlO2JKSzVyPUCuNFExPzNizszN NWPvb2Z3W0GQR1XS
BB49-HNC M4H6Tmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmK2TWM2OD1yLkCxNFc4KM7:TR?= NUPzWJdGW0GQR1XS
IA-LM NIrtPGhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml7lTWM2OD1yLkCxNFg3KM7:TR?= MV7TRW5ITVJ?
NB69 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXLJR|UxRTBwMEGxNFIh|ryP NV\UTIdEW0GQR1XS
C8166 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2fqdGlEPTB;MD6wNVEzQSEQvF2= NXv2NlF4W0GQR1XS
NCI-H1299 M17zOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXLJR|UxRTBwMEGxOVQh|ryP M2DUN3NCVkeHUh?=
YKG-1 MlLOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{HzXWlEPTB;MD6wNVE3KM7:TR?= MmrNV2FPT0WU
PANC-03-27 Ml;DS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUTJR|UxRTBwMEGxOlIh|ryP NFLpXlVUSU6JRWK=
YT MnrKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3zOUWlEPTB;MD6wNVE4QSEQvF2= MYDTRW5ITVJ?
CAL-85-1 NH\vOnZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{XlVGlEPTB;MD6wNVE6OiEQvF2= Mon4V2FPT0WU
GT3TKB MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NELaW4lKSzVyPUCuNFEzODJizszN MWHTRW5ITVJ?
BB65-RCC NIC3bIFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWnJR|UxRTBwMEGyNFQh|ryP MoXmV2FPT0WU
ES6 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{Wze2lEPTB;MD6wNVI3OSEQvF2= M3jBWHNCVkeHUh?=
MHH-ES-1 NWDvZZhXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIm0cnpKSzVyPUCuNFEzPjNizszN MUfTRW5ITVJ?
QIMR-WIL M4DnPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEXuSpRKSzVyPUCuNFEzPjlizszN NISyVVJUSU6JRWK=
SNU-C2B NVPtNJhFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MY\JR|UxRTBwMEGyO|Ih|ryP NHW2cmdUSU6JRWK=
OCI-AML2 MlTkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MojmTWM2OD1yLkCxNlgyKM7:TR?= MmjyV2FPT0WU
DU-145 NH;4dmNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmLpTWM2OD1yLkCxNlkh|ryP Mki3V2FPT0WU
SW982 NX;l[lNkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGLKT|JKSzVyPUCuNFEzQTNizszN NYOxRVVPW0GQR1XS
MFH-ino NWKyNY86T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3r2Z2lEPTB;MD6wNVI6OyEQvF2= MkDGV2FPT0WU
A427 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIm2OZJKSzVyPUCuNFEzQTlizszN M{fYV3NCVkeHUh?=
LCLC-97TM1 NIrrVllIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mk\KTWM2OD1yLkCxN{DPxE1? NUCyXmJuW0GQR1XS
AM-38 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX7pXplOUUN3ME2wMlAyOzB{IN88US=> MonOV2FPT0WU
K5 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV3JR|UxRTBwMEGzNFgh|ryP MojLV2FPT0WU
T84 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIXjeI5KSzVyPUCuNFE{OzFizszN MnvZV2FPT0WU
TE-15 M1yxc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1HPfWlEPTB;MD6wNVM{PiEQvF2= NIPRc4NUSU6JRWK=
NCI-H460 MnGyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEDPdY5KSzVyPUCuNFE{OzZizszN M{DVTXNCVkeHUh?=
NTERA-S-cl-D1 NEXVVndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml7JTWM2OD1yLkCxN|M6KM7:TR?= MXjTRW5ITVJ?
KYSE-450 NHjhcoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUDLbYVsUUN3ME2wMlAyOzR7IN88US=> NVy4[FA5W0GQR1XS
H4 NGSzcGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTBwMEGzOlYh|ryP Ml32V2FPT0WU
LC-2-ad NVfse4c5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHrZ[VFKSzVyPUCuNFE{PyEQvF2= MV;TRW5ITVJ?
GAMG NVy0NIQyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUPuWpFGUUN3ME2wMlAyOzdzIN88US=> NXLNeYFOW0GQR1XS
TK10 NVu1bJd7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWDw[4VCUUN3ME2wMlAyOzh{IN88US=> NIO0[4RUSU6JRWK=
NCI-H2122 M{PwPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlqxTWM2OD1yLkCxN|g1KM7:TR?= NVfvTWQxW0GQR1XS
KM12 NW\LPJdFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXjJR|UxRTBwMEGzPVkh|ryP NYrOSHBrW0GQR1XS
CAL-39 MnGyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3zWdGlEPTB;MD6wNVQzKM7:TR?= NGnzVYZUSU6JRWK=
RPMI-2650 NXnFOm05T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF;KZ2hKSzVyPUCuNFE1OzJizszN M{T4VnNCVkeHUh?=
KYSE-510 NHv6RpZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYnD[|V5UUN3ME2wMlAyPDR{IN88US=> MUTTRW5ITVJ?
KALS-1 NYTwdZJFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGP6cGRKSzVyPUCuNFE1PjZizszN NWHkVGdDW0GQR1XS
NCI-H1648 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NILHWm9KSzVyPUCuNFE1QTlizszN Mn3RV2FPT0WU
ES4 M1jU[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIfBNoNKSzVyPUCuNFE2ODJizszN MkC2V2FPT0WU
C-33-A NXi2c4lVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGDmPGFKSzVyPUCuNFE2ODlizszN MkL1V2FPT0WU
MIA-PaCa-2 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFzGfG5KSzVyPUCuNFE2ODlizszN NH;LRXJUSU6JRWK=
Becker MlnLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVzJR|UxRTBwMEG1NVQh|ryP MmXVV2FPT0WU
HOP-62 NH;sfJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHXF[HZKSzVyPUCuNFE2PDJizszN MYPTRW5ITVJ?
TE-1 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEHxTW9KSzVyPUCuNFE2QDFizszN M3LKUHNCVkeHUh?=
KYSE-410 NXrTXnZwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUS3bVNCUUN3ME2wMlAyPTh4IN88US=> NHS2TWtUSU6JRWK=
NOS-1 NEnpOYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MU\JR|UxRTBwMEG1PVMh|ryP MWHTRW5ITVJ?
MEL-HO NVrSPIhXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3HP[2lEPTB;MD6wNVY1OyEQvF2= M4PES3NCVkeHUh?=
NCI-H1650 NUfpbWRYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXLJR|UxRTBwMEG2OFYh|ryP MVPTRW5ITVJ?
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JiyoyeP-2003 NYDwSZlzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX7JR|UxRTBwMEOzPFgh|ryP M4jRRnNCVkeHUh?=
BL-70 NVfjUZVlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIXwbZdKSzVyPUCuNFM{QDlizszN MoW1V2FPT0WU
OS-RC-2 NX;6NZRvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUjJR|UxRTBwMEOzPVYh|ryP M{\p[HNCVkeHUh?=
SF268 NGTZWnRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2LzVmlEPTB;MD6wN|QxOSEQvF2= NF6zTHhUSU6JRWK=
BV-173 NGrPO4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHPCOVhKSzVyPUCuNFM1OjZizszN M4\mUXNCVkeHUh?=
DMS-273 Mle1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEPFSnJKSzVyPUCuNFM1PzlizszN MXzTRW5ITVJ?
22RV1 MlznS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVv0dpc1UUN3ME2wMlA{PTB5IN88US=> NWLaWXhoW0GQR1XS
ES8 M1vubGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlT0TWM2OD1yLkCzOVM5KM7:TR?= MoizV2FPT0WU
KYSE-150 M{TjO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MY\JR|UxRTBwMEO2NFgh|ryP MX7TRW5ITVJ?
HCC1569 NVmzbpJHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI\IO3VKSzVyPUCuNFM3ODhizszN NYHNbldWW0GQR1XS
NB5 M3T5TWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmXBTWM2OD1yLkCzOlE{KM7:TR?= MVLTRW5ITVJ?
G-402 NYXXXYxwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEPF[W1KSzVyPUCuNFM3OTRizszN NHPxW2hUSU6JRWK=
NCI-H1693 NVrIcJp6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEK3OYhKSzVyPUCuNFM3OTdizszN NEfOUHlUSU6JRWK=
LB2241-RCC M{nOdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoiwTWM2OD1yLkCzOlQzKM7:TR?= M4DkS3NCVkeHUh?=
KP-4 NEXUWI1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlvZTWM2OD1yLkCzOlY{KM7:TR?= M{e3WnNCVkeHUh?=
ML-2 MoXzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWLE[Fh2UUN3ME2wMlA{PjdzIN88US=> NIC3OWpUSU6JRWK=
KU812 M4LyNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUj3O2dKUUN3ME2wMlA{Pjh2IN88US=> NF;lSpFUSU6JRWK=
LS-411N NHHIc5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnSd|h2UUN3ME2wMlA{PzNzIN88US=> MXrTRW5ITVJ?
OAW-42 M{jt[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRTBwMEO3OFch|ryP M33HfXNCVkeHUh?=
HCC38 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml3iTWM2OD1yLkCzO|cyKM7:TR?= M2nlVXNCVkeHUh?=
Ca-Ski MnzIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4jxSmlEPTB;MD6wN|c5PCEQvF2= M{nJWnNCVkeHUh?=
Calu-3 NHXGNpBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4nzdGlEPTB;MD6wN|c5QSEQvF2= NUnXbGxpW0GQR1XS
KYSE-70 NYjIO3pzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV\aVHhwUUN3ME2wMlA{QDF{IN88US=> Ml35V2FPT0WU
D-392MG M13UN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVW0NWFqUUN3ME2wMlA{QDR{IN88US=> M33iT3NCVkeHUh?=
OVCAR-4 MnvTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTBwMEO4OVgh|ryP MUTTRW5ITVJ?
Detroit562 MnqzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlrVTWM2OD1yLkCzPFczKM7:TR?= NXPIUnRvW0GQR1XS
HEL MkX5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnPFTWM2OD1yLkCzPFkyKM7:TR?= NWi2WHJsW0GQR1XS
MONO-MAC-6 NWq0WG9[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFjqWIFKSzVyPUCuNFM5QTNizszN NF3tZYlUSU6JRWK=
LoVo NVPHTWZwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml64TWM2OD1yLkCzPVM{KM7:TR?= MXTTRW5ITVJ?
U-2-OS MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHxTWM2OD1yLkCzPVM2KM7:TR?= M3H4dXNCVkeHUh?=
A172 NUiwdoFRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkfOTWM2OD1yLkCzPVUh|ryP NVrBT|RjW0GQR1XS
OCUB-M MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIHVO|FKSzVyPUCuNFM6PjFizszN NF\EW4VUSU6JRWK=
SW48 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGO5e5hKSzVyPUCuNFQxOzFizszN NWrxcY1uW0GQR1XS
HC-1 M2T6NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4\aUGlEPTB;MD6wOFA3QSEQvF2= NIHmV45USU6JRWK=
KOSC-2 M2C5c2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmTJTWM2OD1yLkC0NVEh|ryP NHzwUYNUSU6JRWK=
HDLM-2 M1vnNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGL4ZphKSzVyPUCuNFQyOTRizszN NVrHeIVpW0GQR1XS
CTV-1 NFnmZnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYHJR|UxRTBwMESxNVYh|ryP M1j6T3NCVkeHUh?=
SH-4 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIH6VZVKSzVyPUCuNFQyPDFizszN NF;sfoFUSU6JRWK=
SW756 NVfJXIFsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYLJR|UxRTBwMESxOVch|ryP M2fEZ3NCVkeHUh?=
GCT M4i2R2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{XmXWlEPTB;MD6wOFE3OSEQvF2= M1\Sd3NCVkeHUh?=
CHL-1 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mnm1TWM2OD1yLkC0NVY6KM7:TR?= MXTTRW5ITVJ?
LAMA-84 MljsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFXtTFdKSzVyPUCuNFQyPzFizszN NH7i[m9USU6JRWK=
LS-1034 NU\SOXhRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV\DUHFsUUN3ME2wMlA1OTlzIN88US=> NIS3WpFUSU6JRWK=
NCI-H358 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH7OSIJKSzVyPUCuNFQzOTJizszN MYLTRW5ITVJ?
NB13 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHGxOFJKSzVyPUCuNFQzOjdizszN MYPTRW5ITVJ?
TE-9 NXPnV3BIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXzYXo5YUUN3ME2wMlA1OjN5IN88US=> MXvTRW5ITVJ?
OE33 NFPTOnJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWXJR|UxRTBwMESyOFEh|ryP NG\rfIdUSU6JRWK=
CAL-120 M3\TRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml7wTWM2OD1yLkC0NlQyKM7:TR?= MUjTRW5ITVJ?
DJM-1 NEXzWZZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIG3OJZKSzVyPUCuNFQzPzJizszN M{S5TXNCVkeHUh?=
SK-MEL-24 NFrO[JNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV;JR|UxRTBwMESyPFMh|ryP NGKzVWhUSU6JRWK=
VA-ES-BJ NV\2SWl[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFfuOIpKSzVyPUCuNFQzQTJizszN MnXLV2FPT0WU
MMAC-SF NIXTXGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2TGfmlEPTB;MD6wOFI6PyEQvF2= NHLSS|RUSU6JRWK=
MZ7-mel MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUO3fopmUUN3ME2wMlA1OzNizszN MV\TRW5ITVJ?
BxPC-3 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTBwMESzOFEh|ryP MXLTRW5ITVJ?
HT-29 NEXJNVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFTrVJNKSzVyPUCuNFQ{PTdizszN NFL0UHVUSU6JRWK=
SK-MEL-30 M2DufGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoDETWM2OD1yLkC0N|YzKM7:TR?= M2\SUHNCVkeHUh?=
CAL-33 NFv5O5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoXzTWM2OD1yLkC0N|c2KM7:TR?= MkfZV2FPT0WU
COLO-680N NWDsXo12T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1j1fGlEPTB;MD6wOFQxPyEQvF2= MWHTRW5ITVJ?
NH-12 MlH4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVzJR|UxRTBwMES0OEDPxE1? NY\GfIxVW0GQR1XS
HCC1937 NV[3UXpsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH;ZT5RKSzVyPUCuNFQ1PTZizszN M13BVHNCVkeHUh?=
IMR-5 NXLqSXhZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnvRTWM2OD1yLkC0OFkh|ryP MYTTRW5ITVJ?
MC-CAR NXfkTYpST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUjic4Z6UUN3ME2wMlA1PTZ7IN88US=> NETTOGVUSU6JRWK=
NCI-H747 NG\xZ5lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVfYbXd[UUN3ME2wMlA1PTdizszN M3PaRXNCVkeHUh?=
NCI-H1792 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1HsZ2lEPTB;MD6wOFU5OSEQvF2= NILMNXpUSU6JRWK=
SW13 M2fCPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXO0U5BFUUN3ME2wMlA1PTlizszN M16yfHNCVkeHUh?=
MLMA MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGfhW21KSzVyPUCuNFQ3ODlizszN MnTkV2FPT0WU
U251 NGfKWoFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml;kTWM2OD1yLkC0O|Y{KM7:TR?= NHnBeYNUSU6JRWK=
U031 NHvzXZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFvrXHdKSzVyPUCuNFQ4PzFizszN MWrTRW5ITVJ?
ME-180 MnzHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmrpTWM2OD1yLkC0O|gzKM7:TR?= NEC2[WZUSU6JRWK=
SK-MEL-3 MkfWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4nEXmlEPTB;MD6wOFgxOiEQvF2= MXzTRW5ITVJ?
MOLT-4 NYDsO4FXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnjGTWM2OD1yLkC0PFA{KM7:TR?= M3i0cHNCVkeHUh?=
PF-382 MkK0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWjw[VJEUUN3ME2wMlA1QDJ4IN88US=> NEW4bIFUSU6JRWK=
NUGC-3 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUPJR|UxRTBwMES4Nlch|ryP MmXwV2FPT0WU
NCI-H1417 MnXDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXfMeVV2UUN3ME2wMlA1QDlizszN Ml7XV2FPT0WU
COLO-205 M4D1UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUfsPFlnUUN3ME2wMlA1QTF7IN88US=> MnPxV2FPT0WU
TE-441-T NHH6TFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXWzTGhjUUN3ME2wMlA1QTNizszN MVjTRW5ITVJ?
MKN1 NEX4SZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXTJR|UxRTBwMES5N{DPxE1? NXq5NVB6W0GQR1XS
UM-UC-3 M{DzS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mo\uTWM2OD1yLkC0PVUh|ryP NH3le2tUSU6JRWK=
SF126 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYjLSpRMUUN3ME2wMlA2ODFizszN MWXTRW5ITVJ?
LB1047-RCC MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXq3dnhVUUN3ME2wMlA2ODNzIN88US=> NYnjXWY3W0GQR1XS
A253 M3\veGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF7DfYFKSzVyPUCuNFUxPTJizszN M{jHSHNCVkeHUh?=
NCI-H1963 NF7iWGJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlHMTWM2OD1yLkC1NVc3KM7:TR?= MVPTRW5ITVJ?
VM-CUB-1 M1XRd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUHxOpNqUUN3ME2wMlA2OzFzIN88US=> MoD4V2FPT0WU
T-24 M{nwW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NG\DO|BKSzVyPUCuNFU{QDRizszN NH75TIRUSU6JRWK=
K-562 NHnXbllIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV34blZ1UUN3ME2wMlA2Ozh5IN88US=> M4fDNHNCVkeHUh?=
ARH-77 M3XJOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHf3dIxKSzVyPUCuNFU{QTVizszN MWrTRW5ITVJ?
CA46 NHjxOItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVjJR|UxRTBwMEW0N{DPxE1? MkT3V2FPT0WU
HCC70 NWXIUo1YT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWTJR|UxRTBwMEW0OVIh|ryP NYP4[YVvW0GQR1XS
ST486 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnTHTWM2OD1yLkC1OVI2KM7:TR?= NGe0O|lUSU6JRWK=
COLO-741 M3XYWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEfRNXBKSzVyPUCuNFU2OzFizszN MoLnV2FPT0WU
SK-PN-DW M{\BcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlO2TWM2OD1yLkC1OVg5KM7:TR?= M1rnTHNCVkeHUh?=
BL-41 MnyxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHLFV|JKSzVyPUCuNFU2QTZizszN M2HvN3NCVkeHUh?=
D-263MG M{j4V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVP1[2JCUUN3ME2wMlA2Pjh|IN88US=> MlTHV2FPT0WU
KE-37 M{fQd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3e0emlEPTB;MD6wOVY5OyEQvF2= MnPCV2FPT0WU
LU-134-A NV3YWHRwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV;jXXR1UUN3ME2wMlA2PzF3IN88US=> M4Lv[nNCVkeHUh?=
HCC2157 MkPrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF36OXpKSzVyPUCuNFU4OzNizszN M4i3VXNCVkeHUh?=
GAK M2q1O2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTBwMEW3N|Qh|ryP MUXTRW5ITVJ?
IST-SL2 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MU\JR|UxRTBwMEW3OFMh|ryP NXjNWolUW0GQR1XS
KMOE-2 NEfUNFFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml3WTWM2OD1yLkC1O|Q6KM7:TR?= MUTTRW5ITVJ?
SW1573 M3fMXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIrYdoZKSzVyPUCuNFU5ODJizszN M17FPXNCVkeHUh?=
SCC-9 M{OyS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVPJR|UxRTBwMEW4O{DPxE1? M3zjdnNCVkeHUh?=
MDA-MB-361 NWjzUFhiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUPtWnU1UUN3ME2wMlA2QDd{IN88US=> MXXTRW5ITVJ?
BHT-101 M33iTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoXwTWM2OD1yLkC1PFc3KM7:TR?= M3f3cnNCVkeHUh?=
NCI-H1770 NXixRVNKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFLLcFJKSzVyPUCuNFU5PzlizszN MYnTRW5ITVJ?
UACC-893 NVH0d3A5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnnqTWM2OD1yLkC1PFk3KM7:TR?= MUHTRW5ITVJ?
NCI-H226 NFXX[G1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MljWTWM2OD1yLkC1PVg5KM7:TR?= MYHTRW5ITVJ?
HLE NVPCZnM{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH;6RmNKSzVyPUCuNFYxQDJizszN MkG2V2FPT0WU
NCI-H1703 MkP6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYLJR|UxRTBwME[xO|gh|ryP M16w[HNCVkeHUh?=
KURAMOCHI MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVOwUopwUUN3ME2wMlA3OTh7IN88US=> MWHTRW5ITVJ?
RH-1 NV7DUJRFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH\LW2JKSzVyPUCuNFYzOyEQvF2= NHL1fYFUSU6JRWK=
DSH1 NHXpbWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYHJR|UxRTBwME[yO{DPxE1? M1HUWHNCVkeHUh?=
CAMA-1 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUXJR|UxRTBwME[zNFMh|ryP MXLTRW5ITVJ?
NCI-H1437 NIDmb29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV7JR|UxRTBwME[zNlgh|ryP NXL5bWo2W0GQR1XS
HuP-T4 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEHEW21KSzVyPUCuNFY2QDZizszN MUTTRW5ITVJ?
HCT-15 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWXJR|UxRTBwME[1PVch|ryP NHXzfZJUSU6JRWK=
NCCIT NH;RfHFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2DSVGlEPTB;MD6wOlYxPCEQvF2= MV;TRW5ITVJ?
BOKU M4riWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1\FPGlEPTB;MD6wOlY4PCEQvF2= NFjaV4VUSU6JRWK=
FADU MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWHJR|UxRTBwME[3OFUh|ryP M3PR[nNCVkeHUh?=
SUP-T1 Mnq0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUC4fHMzUUN3ME2wMlA3PzZizszN NX3SO4Y5W0GQR1XS
L-363 Moj6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2XPeGlEPTB;MD6wOlkxOSEQvF2= NIq3[3VUSU6JRWK=
KNS-81-FD M4HHNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVHJR|UxRTBwME[5NVgh|ryP NXWxdGc{W0GQR1XS
SU-DHL-1 MluwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWrJR|UxRTBwME[5NkDPxE1? MYXTRW5ITVJ?
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NCI-H526 M2K1eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkjNTWM2OD1yLkG4Olk3KM7:TR?= MW\TRW5ITVJ?
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LU-65 NHixTGlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmfrTWM2OD1yLkKwNlEyKM7:TR?= MmO2V2FPT0WU
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NCI-H2196 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmLCTWM2OD1yLkKxO|Q4KM7:TR?= MV3TRW5ITVJ?
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NCI-H1436 M4nKbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmLHTWM2OD1yLkKxPFI3KM7:TR?= NH3MdJZUSU6JRWK=
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LB647-SCLC M3zTV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXOyVYxiUUN3ME2wMlI1ODF2IN88US=> NGjHRnpUSU6JRWK=
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TE-6 M4XMZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVXOfmZjUUN3ME2wMlI1PjF{IN88US=> M371NHNCVkeHUh?=
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NCI-H1618 NIHQNpZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn;YTWM2OD1yLkK3OVEh|ryP NH\zXHFUSU6JRWK=
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NCI-H510A M121OGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkHqTWM2OD1yLkK5N|A1KM7:TR?= Mn;vV2FPT0WU
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LB373-MEL-D NV32Z|BFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI\tT5NKSzVyPUCuNlk1OzFizszN MnK0V2FPT0WU
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NCI-H446 M{jTUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWrZclZTUUN3ME2wMlI6QTJzIN88US=> NUHWU2syW0GQR1XS
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DMS-114 NIPZWFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWfJR|UxRTBwM{[xNkDPxE1? MXrTRW5ITVJ?
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D-502MG MmDjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYfJR|UxRTBwNEiwN{DPxE1? M2i2fXNCVkeHUh?=
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RPMI-8402 M{D6Z2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MljYTWM2OD1yLkWyNlA4KM7:TR?= MUXTRW5ITVJ?
SW1088 NFzlO5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXLJR|UxRTBwNUO4Olkh|ryP MYHTRW5ITVJ?
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C32 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlK4TWM2OD1yLkW3N|E{KM7:TR?= MVPTRW5ITVJ?
IST-SL1 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1Xh[mlEPTB;MD62NFQ{PSEQvF2= MnvKV2FPT0WU
NCI-H2126 M1XjTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEnqT4NKSzVyPUCuOlMyPTJizszN NVjzRnJlW0GQR1XS
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TYK-nu MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXPTNop3UUN3ME2wMlY4QTV{IN88US=> Mn7EV2FPT0WU
KY821 NWX5PHhIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYjJR|UxRTBwN{CyNlkh|ryP MUHTRW5ITVJ?
SIMA MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVfJR|UxRTBwN{G3NVkh|ryP MoPMV2FPT0WU
RCC10RGB M3;4Nmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHPES4VKSzVyPUCuO|E6OThizszN Mln6V2FPT0WU
LN-405 NGXoPI5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVPJR|UxRTBwN{SzOkDPxE1? MX7TRW5ITVJ?
NCI-H1155 NF7IZnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1XIOWlEPTB;MD63OFg3QCEQvF2= NEDhbZVUSU6JRWK=
SCLC-21H MnnaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIHF[plKSzVyPUCuO|Y6ODNizszN M4XZfnNCVkeHUh?=
DMS-79 M3XvRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2[wV2lEPTB;MD63O|g1PSEQvF2= NVLUVnF[W0GQR1XS
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KNS-42 NH\meJNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTBwN{i4N|Eh|ryP NUOxZYhwW0GQR1XS
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SF539 MkXrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFrNT2NKSzVyPUCuO|k6OjVizszN NEf1NoRUSU6JRWK=
SW1417 MlrMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYfJR|UxRTBwOEGzN|kh|ryP NITybGNUSU6JRWK=
ATN-1 NUTVXFNET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYLSV4FLUUN3ME2wMlg2OTF3IN88US=> NHPUcVlUSU6JRWK=
PLC-PRF-5 NELEV5JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkfVTWM2OD1yLki4OFc2KM7:TR?= MkPCV2FPT0WU
HT-3 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoD0TWM2OD1yLki5OFIh|ryP NEnXOJZUSU6JRWK=
MDA-MB-453 MnzsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTBwOUCzNFQh|ryP M{nxT3NCVkeHUh?=
HAL-01 M{DNS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFnDUHFKSzVyPUCuPVk{PzlizszN M4XNcHNCVkeHUh?=
NCI-H1993 MmjGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4fRO2lEPTB;MT6wOFY2PyEQvF2= MnTVV2FPT0WU
NCI-H2227 M1TGbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnLSTWM2OD1zLkC0PVgyKM7:TR?= M3HCZnNCVkeHUh?=
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NCI-H64 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmX3TWM2OD1zLkG1OFIh|ryP NFHJfoVUSU6JRWK=
SW1463 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnnyTWM2OD1zLkG4N|Q6KM7:TR?= NFfjNGVUSU6JRWK=
SK-MEL-1 NHLSd|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW\wbmJ3UUN3ME2xMlIxPTl3IN88US=> M1Tsc3NCVkeHUh?=
TALL-1 NFrlfJNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUG1[G1CUUN3ME2xMlI2OTZ3IN88US=> M3rI[HNCVkeHUh?=
RO82-W-1 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXPJR|UxRTFwM{OzN|kh|ryP MUHTRW5ITVJ?
NCI-H1581 M{\Vemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV7JR|UxRTFwM{W2PFch|ryP NVfmWpRyW0GQR1XS
NCI-H748 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXPJR|UxRTFwM{W3N|gh|ryP NGPwN41USU6JRWK=
HCC1187 M1L1cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYX6V|RpUUN3ME2xMlU2PTJ{IN88US=> M1\zTnNCVkeHUh?=
EoL-1-cell M4\DT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NILiW4dKSzVyPUGuOVg5QDlizszN MUjTRW5ITVJ?
HuO-3N1 NXK2eXB2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4e3XGlEPTB;MT64N|QyOiEQvF2= M{HIN3NCVkeHUh?=
NCI-H1793 NV7kN5lET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1X3[WlEPTB;MT64O|U6OyEQvF2= MmLsV2FPT0WU
Caov-3 NGDiWZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVTJR|UxRTJwMEC2NlUh|ryP M4nMPXNCVkeHUh?=
JAR MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUDJR|UxRTJwMEe5NkDPxE1? M1PyOXNCVkeHUh?=
SK-MEL-28 M4LZRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVrJR|UxRTJwMUiwPVgh|ryP NHT4bVRUSU6JRWK=
EM-2 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYnJR|UxRTJwMkCyPVMh|ryP M3HxVnNCVkeHUh?=
Mewo NULjfpd4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXXJR|UxRTJwMkKyOlUh|ryP MlHXV2FPT0WU
NCI-H720 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIXzdFBKSzVyPUKuNlY2QDVizszN M4Xv[HNCVkeHUh?=
CAL-54 NVXSS2xGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX3JR|UxRTJwMk[3PVUh|ryP NHjVPI5USU6JRWK=
MC116 NHTQVXZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFnYVIRKSzVyPUKuN|Y{QTdizszN M{LNUnNCVkeHUh?=
DG-75 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHTOo0yUUN3ME2yMlQ5PTd4IN88US=> NELhNYtUSU6JRWK=
HCC1143 Mn;MS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{XL[WlEPTB;Mj61NFY2QCEQvF2= MWHTRW5ITVJ?
FTC-133 M1e2[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEf1S5VKSzVyPUKuOVM3QDlizszN MYfTRW5ITVJ?
AsPC-1 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHPO2FrUUN3ME2yMlU{QTJ7IN88US=> MnnVV2FPT0WU
NCI-H889 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUPyUG1YUUN3ME2yMlU3PzB4IN88US=> MWXTRW5ITVJ?
HT55 NFHlZYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjvTWM2OD1{Lk[yNFE6KM7:TR?= NV35eYNnW0GQR1XS
UMC-11 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUPJR|UxRTJwN{i3NVUh|ryP NHHzW|dUSU6JRWK=
P12-ICHIKAWA M3PBZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml3pTWM2OD1{LkiyNFQ3KM7:TR?= NVLTbZR6W0GQR1XS
HCC1395 M2HHN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1LJdGlEPTB;Mj65PFYxOiEQvF2= M122VXNCVkeHUh?=
D-283MED NGnMS2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnzBTWM2OD1|LkG4PVM4KM7:TR?= M3PjWnNCVkeHUh?=
COLO-800 NE\aSJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW\xb2hsUUN3ME2zMlM{QDl5IN88US=> NGPYOlZUSU6JRWK=
MFM-223 M3T6fmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWLJR|UxRTNwM{[wPVch|ryP Mlm1V2FPT0WU
TE-5 M1GySGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGntPXpKSzVyPUSuOVYyPDdizszN MlPZV2FPT0WU
NCI-H209 NUDPcnBKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIXxU|JKSzVyPUSuO|g2PzJizszN NUTkdXo{W0GQR1XS
SiHa MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTRwOUWyNFMh|ryP NFXHN3VUSU6JRWK=
NCI-H1395 MnfJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUnqfGN2UUN3ME21MlExPjN|IN88US=> MljlV2FPT0WU
A498 M3jUVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTVwMkGyOVEh|ryP NIDWdY5USU6JRWK=
ES5 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3nzbWlEPTB;NT62NVE4QCEQvF2= NEn0SVdUSU6JRWK=
MDA-MB-157 M3zBOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1LmW2lEPTB;NT62OlQ1OyEQvF2= NUPNZYlEW0GQR1XS
NCI-H1623 NHPYe2RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2nCXGlEPTB;NT64N|U2PiEQvF2= MY\TRW5ITVJ?
RPMI-8866 MoH5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXrJR|UxRTVwOES3PVIh|ryP MWrTRW5ITVJ?
LC-1F MlfIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEDJeXFKSzVyPU[uNFkzQTFizszN NUXMWJh1W0GQR1XS
TCCSUP NVPF[plLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGm4Z5FKSzVyPU[uOlA{PDlizszN MWTTRW5ITVJ?
TT M3Ta[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV\xZ4RnUUN3ME24MlM{ODB7IN88US=> M33uXXNCVkeHUh?=
NCI-H1838 NWK1WFdCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJR|UxRThwNUG3N|Eh|ryP MkL4V2FPT0WU
NCI-H322M NFHaTodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn3CTWM2OD17LkG2NlgyKM7:TR?= NWr1ZphLW0GQR1XS
NCI-H187 MkPGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHzzVYtKSzVyPUmuOVE5OzVizszN MlTmV2FPT0WU
SBC-1 M4LTTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUDJR|UxRTlwOUO2OVYh|ryP M{fPVnNCVkeHUh?=
SCC-3 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnrCTWM2OD1zMD61Olc6KM7:TR?= MYnTRW5ITVJ?
SW948 M3PNd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF7RclFKSzVyPUGwMlc2OTFizszN MUPTRW5ITVJ?
CPC-N MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXfJR|UxRTFzLkCwO{DPxE1? NHi1OmJUSU6JRWK=
TGBC24TKB NFzkOFhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYjXd|NvUUN3ME2xN{42OjlizszN MmXCV2FPT0WU
NCI-H2452 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2HGNmlEPTB;MUSuO|Mh|ryP NYraSmpKW0GQR1XS
Hs-578-T M{nLTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkD3TWM2OD1zOD61O|U6KM7:TR?= NFTF[JVUSU6JRWK=
DV-90 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTF6Lkm5OFUh|ryP MWPTRW5ITVJ?
NCI-H1563 MmTsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NE\MdYNKSzVyPUG5Mlc5QDhizszN M37LVnNCVkeHUh?=
SW780 M{i3O2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFfwN3pKSzVyPUKxMlE{OThizszN M1zrTXNCVkeHUh?=
NCI-H345 NIW2WGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEP0SXFKSzVyPUKxMlg4PzlizszN Ml[xV2FPT0WU
LB771-HNC MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlvJTWM2OD1{Mj60PFE{KM7:TR?= Ml\hV2FPT0WU
RT4 M4DLXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYi5OJU1UUN3ME2yN{4{Ojh{IN88US=> NF3XdVJUSU6JRWK=
NCI-H82 Mn7ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2j0ZmlEPTB;MkOuOVUzPiEQvF2= NXzOd5NsW0GQR1XS
NCI-H524 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoLhTWM2OD1{ND6zPFEzKM7:TR?= M4nOS3NCVkeHUh?=
SNU-C1 NVfIOWhTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVXJR|UxRTJ2LkmxNFUh|ryP MUjTRW5ITVJ?
NCI-SNU-16 NFH3RolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWHJR|UxRTR6LkOxOFIh|ryP NVHsZYN6W0GQR1XS

... Click to View More Cell Line Experimental Data

In vivo Treatment with NVP-AUY922 causes a robust antitumor response and inhibits p-Akt and VEGF expression in an HSC-2 xenograft model. [2] In BT474, NVP-AUY922 shows complete loss of ERBB2 and substantial depletion of ERα, in addition to reductions in CDK4 and phospho-ERK1/2. [3]

Protocol

Kinase Assay:[3]
+ Expand

Kinase assay:

NVP-AUY922 is dissolved in DMSO at a concentration of 10 mM. NVP-AUY922 is assessed against HSP90α, HSP90β, GRP94, TRAP-1, HSP72, and topoisomerase II. Profiling against a panel of kinases has been carried out and screening against a panel of additional enzymes and receptors is performed at Cerep.
Cell Research:[1]
+ Expand
  • Cell lines: Human gastric cancer cells NCI-N87
  • Concentrations: 1 μM
  • Incubation Time: 3 days
  • Method: Human gastric cancer cells NCI-N87 (5-7 ×103 in 50 μL/well) are seeded in 96-well plates and incubated at 37 °C for 24 hours, followed by NVP-AUY922 treatment for 1-3 days at 37 °C. After treatment, the cells are assayed by MTT method and analyzed by microplate reader.
    (Only for Reference)
Animal Research:[3]
+ Expand
  • Animal Models: Female NCr athymic mice bearing WM266.4 human melanoma xenografts
  • Formulation: In DMSO and diluted in sterile saline/Tween 20
  • Dosages: 50 mg/kg
  • Administration: Administered via i.v. or i.p.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 93 mg/mL warmed (199.76 mM)
Ethanol 31 mg/mL (66.58 mM)
Water Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
1% DMSO+30% polyethylene glycol+1% Tween 80
For best results, use promptly after mixing.
30 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 465.54
Formula

C26H31N3O5

CAS No. 747412-49-3
Storage powder
in solvent
Synonyms VER-52296

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01922583 Completed Non-small Cell Lung Cancer (NSCLC) National Taiwan University Hospital January 2014 Phase 2
NCT01784640 Active not recruiting Recurrent Non-small Cell Lung Cancer|Squamous Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer Jonsson Comprehensive Cancer Center|National Cancer Institute (NCI) January 31 2014 Phase 1
NCT01922583 Completed Non-small Cell Lung Cancer (NSCLC) National Taiwan University Hospital January 2014 Phase 2
NCT01784640 Active not recruiting Recurrent Non-small Cell Lung Cancer|Squamous Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer Jonsson Comprehensive Cancer Center|National Cancer Institute (NCI) January 31 2014 Phase 1
NCT01854034 Completed Non Small Cell Lung Cancer Massachusetts General Hospital July 2013 Phase 2
NCT01854034 Completed Non Small Cell Lung Cancer Massachusetts General Hospital July 2013 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

HSP (e.g. HSP90) Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID