Home GPCR & G Protein MT Receptor antagonist Luzindole For research use only.

Luzindole

Synonyms: N-0774

Luzindole (N-0774, N-acetyl-2-benzyltryptamine) is a selective melatonin receptor antagonist with Kis of 179 nM for MT1 and 7.3 nM for MT2, respectively.

Luzindole Chemical Structure

Luzindole Chemical Structure

CAS: 117946-91-5

Selleck's Luzindole has been cited by 2 publications

Purity & Quality Control

Batch: S358401 DMSO] 58 mg/mL] false] Ethanol] 58 mg/mL] false] Water] Insoluble] false Purity: 99.47%
99.47

Luzindole Related Products

Signaling Pathway

MT Receptor Signaling Pathways

MT Receptor Signaling Pathway

Choose Selective MT Receptor Inhibitors

Biological Activity

Description Luzindole (N-0774, N-acetyl-2-benzyltryptamine) is a selective melatonin receptor antagonist with Kis of 179 nM for MT1 and 7.3 nM for MT2, respectively.
Targets
MT2 [1] MT1 [1]
7.3 nM(Ki) 179 nM(Ki)

Chemical Information & Solubility

Molecular Weight 292.37 Formula

C19H20N2O
CAS No. 117946-91-5 SDF --
Smiles CC(=O)NCCC1=C(CC2=CC=CC=C2)[NH]C3=CC=CC=C13
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 58 mg/mL ( (198.37 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 58 mg/mL

Water : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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