| Catalog No. |
Product Name |
Information |
| S8873 |
Letermovir（AIC246, MK-8228） |
Letermovir(AIC246, MK-8228) is a novel anti-CMV compound which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. |
| S5415 |
Enoxaparin sodium |
Enoxaparin sodium is a low-molecular-weight heparin used to prevent and treat deep vein thrombosis or pulmonary embolism. It binds to and accelerates the activity of antithrombin III. |
| S9321 |
Topotecan |
Topotecan is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases. |
| S2667 |
Dolutegravir (GSK1349572) |
Dolutegravir (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. |
| S2057 |
Cyclophosphamide Monohydrate |
Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and inducing mutations. |
| S1359 |
Losartan Potassium (DuP 753) |
Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. |
| S1415 |
Clopidogrel Bisulfate |
Clopidogrel is an oral, thienopyridine class antiplatelet agent. |
| S1068 |
Crizotinib (PF-02341066) |
Crizotinib (PF-02341066) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1 inhibitor with Ki value less than 0.025 nM. |
| S2760 |
Canagliflozin |
Canagliflozin is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM in a cell-free assay, exhibits 413-fold selectivity over hSGLT1. |
| S5002 |
Fingolimod (FTY720) HCl |
Fingolimod (FTY720) HCl is a S1P antagonist with IC50 of 0.033 nM in K562, and NK cells. |
| S1950 |
Metformin HCl |
Metformin HCl decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). |
| S6492 |
Doravirine (MK-1439) |
Doravirine is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT) and K103N and Y181C reverse transcriptase (RT) mutants, respectively, in a biochemical assay. It is highly specific with minimum off-target activities. |
| S1271 |
Acarbose |
Acarbose is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus. |
| S1698 |
Torsemide |
Torsemide is a pyridyl sulfonylurea with a chemical structure between that of traditional loop diuretics and Cl- channel blockers, used to treat hypertension. |
| S2610 |
Lonidamine |
Lonidamine is an orally administered small molecule hexokinase inactivator. |
| S1858 |
Dienestrol |
Dienestrol(Restrol) is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. |
| S2035 |
Epalrestat |
Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM. |
| S3003 |
Prostaglandin E2 (PGE2) |
Prostaglandin E2 palys important effects in labour (softens cervix and causes uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts.
|
| S4851 |
Tafluprost |
Tafluprost is a novel prostaglandin analog with a high affinity for the fluoroprostaglandin (FP) receptor PGF2α. A prostanoid selective FP receptor agonist. |
| S1508 |
Alprostadil |
Alprostadil is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist. |
