| Catalog No. |
Product Name |
Information |
| S5001 |
Tofacitinib (CP-690550) Citrate |
Tofacitinib citrate (CP-690550 citrate) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. |
| S1028 |
Lapatinib (GW-572016) Ditosylate |
Lapatinib (GW-572016) Ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. |
| S1120 |
Everolimus (RAD001) |
Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM in a cell-free assay. |
| S2789 |
Tofacitinib (CP-690550,Tasocitinib) |
Tofacitinib (CP-690550,Tasocitinib) is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. |
| S3020 |
Romidepsin (FK228, Depsipeptide) |
Romidepsin (FK228, depsipeptide) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM in cell-free assays, respectively. |
| S1430 |
Rolipram |
The PDE4 selective inhibitor, rolipram, inhibited immunopurified PDE4B and PDE4D activities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent. |
| S2807 |
Dabrafenib (GSK2118436) |
Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.7 nM in cell-free assays, with 7- and 9-fold less potency against B-Raf(wt) and c-Raf, respectively. |
| S1858 |
Dienestrol |
Dienestrol(Restrol) is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. |
| S5812 |
Choline Fenofibrate |
Choline fenofibrate is a newly developed choline salt of fenofibric acid, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity that acts as an PPARα agonist. |
| S5781 |
Raloxifene |
Raloxifene is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. |
| S5782 |
Doxazosin |
Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. |
| S5783 |
Montelukast |
Montelukast is a leukotriene receptor antagonist used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. |
| S9567 |
Indinavir Sulfate |
Indinavir sulfate is a specific and potent inhibitor of HIV-1 protease and is widely used in the treatment of AIDS. |
| S9568 |
Sapropterin Dihydrochloride |
Sapropterin Dihydrochloride, a synthetic preparation of the dihydrochloride salt of naturally occurring tetrahydrobiopterin (BH4), is a phenylalanine hydroxylase activator. |
| S9566 |
Bepridil hydrochloride |
Bepridil hydrochloride is an anti-anginal drug classified as a calcium channel blocker. It also blocks multiple other ion channels, including sodium and potassium channels. |
| S2083 |
Procaterol HCl |
Procaterol HCl is a short-acting β2-adrenergic receptor agonist with Kp of 8 nM, used for the treatment of asthma
|
| S5816 |
pyrvinium |
Pyrvinium is an anthelmintic effective for pinworms. |
| S5780 |
Prazosin |
Prazosin is an α1-blocker that acts as an inverse agonist at alpha-1 adrenergic receptors. It is used to treat hypertension. |
| S5787 |
Dronedarone |
Dronedarone is a derivative of amiodarone which is classified as a Class III antiarrhythmic agent. It shows rate-dependent inhibition of the rapid Na+ current, inhibits α and β-adrenergic receptors like Class II agents, exhibits blockade of K+ outward currents as the main mechanism of action of Class III, and effectively block slow Ca2+ inward currents (Class IV). |
| S5795 |
Rasagiline |
Rasagiline is a novel selective and irreversible MAO-B propargylamine inhibitor with in vitro IC50s of 4.43 nM and 412 nM for MAO-B and MAO-A, respectively. |
