L-Tryptophan

Catalog No.S3987

For research use only.

L-tryprophan is an essential amino acid that acts like a natural mood regulator that is necessary for normal growth in infants and for nitrogen balance in adults.

L-Tryptophan Chemical Structure

CAS No. 73-22-3

Purity & Quality Control

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Biological Activity

Description L-tryprophan is an essential amino acid that acts like a natural mood regulator that is necessary for normal growth in infants and for nitrogen balance in adults.
In vivo L-Tryptophan suppresses both serum glucose and insulin levels after oral glucose administration and inhibits glucose absorption from the intestine. It increases glucose-associated energy expenditure in rats in vivo. L-Tryptophan suppresses the rapid rise in blood glucose after a glucose-rich meal and lessens the burden of insulin secretion from β-cells. Oral administration of L-tryptophan is more effective than intraperitoneal injection[1].

Protocol (from reference)

Animal Research:

[1]

  • Animal Models: Four-week-old male normal Sprague-Dawley rats
  • Dosages: 62.5 mg/kg
  • Administration: Oral administration

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 204.23
Formula

C11H12N2O2

CAS No. 73-22-3
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05351333 Not yet recruiting Other: placebo Spinal Cord Injuries|Polytrauma|Burns Spaulding Rehabilitation Hospital|National Institute on Drug Abuse (NIDA) July 1 2022 Not Applicable
NCT05229835 Recruiting Other: Time restricted eating and exercise Physical Exercise|Time Restricted Eating|Mental Health Wellness 1|Wellbeing|Biochemical Markers Medical University of Gdansk January 20 2022 Not Applicable
NCT05155631 Recruiting Behavioral: COGNITIVE BEHAVIORAL THERAPY IBS - Irritable Bowel Syndrome University of California Los Angeles December 18 2021 Not Applicable
NCT05083637 Recruiting Drug: L- carnitine oral solution|Other: Placebo Malnutrition International Centre for Diarrhoeal Disease Research Bangladesh October 19 2021 Not Applicable
NCT04804358 Recruiting Behavioral: Exposition Test Anorexia Nervosa University Hospital Montpellier September 17 2021 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-08-01)

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