Kinase Inhibitor Library

Catalog No.L1200

Offered in 96 or 384 well plate format

A unique collection of 1461 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).

Size

Price

Pre-dissolved In DMSO or Water
100uL/well (2mM or 10mM solution)	USD 24034
2x100uL/well (2mM or 10mM solution)	USD 36822

Selleck USA Tel: (832) 582-8158 [email protected]

Selleck Chemicals compound library contributes and expedites
the investigation of treatments against COVID19

The researchers at the National Institute of Infectious Diseases, in Japan, successfully found anti-COVID19 drugs within 3 months of
screening FDA-approved drug library from Selleck Chemicals. They have already published this article doi: 10.1101/2020.04.14.039925.

Recently the accomplishment of this research, using Selleck Chemicals library, was reported on Japanese television

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Kinase Inhibitor Library Contents

Download the Kinase Inhibitor Library - SDF

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Download the Compound Library Usage Instructions-pdf

Cited by 192 Publications

Nat Methods,2020,17(3):302-310

PubMed: 31932777 ( click the link to review the publication )

Cell Metab,2019,7;29(5):1166-1181.e6.

PubMed: 30799286 ( click the link to review the publication )

Nat Med,2017,23(4):405-408

PubMed: 28388612 ( click the link to review the publication )

Cancer Cell,2017,32(5):684-700

PubMed: 29107533 ( click the link to review the publication )

Gastroenterology,2017,153(5):1429-1443

PubMed: 28764929 ( click the link to review the publication )

Cancer Cell,2015,28(2):240-52

PubMed: 26267537 ( click the link to review the publication )

Nat Med,2014,20(8):954-60

PubMed: 24997607 ( click the link to review the publication )

Nat Commun,2020,14;11(1):1792.

PubMed: 32286289 ( click the link to review the publication )

Cell Syst,2020,10(3):240-253.e6

PubMed: 32191874 ( click the link to review the publication )

Cancer Res,2020,15;80(4):832-842.

PubMed: 31888889 ( click the link to review the publication )

Stem Cell Reports,2020,14(3):478-492

PubMed: 32084387 ( click the link to review the publication )

Cancer Lett,2020,469:195-206

PubMed: 31672491 ( click the link to review the publication )

Cell Death Dis,2020,2;11(3):158.

PubMed: 32123161 ( click the link to review the publication )

Signal Transduct Target Ther,2020,4;5:20.

PubMed: 32195002 ( click the link to review the publication )

Mol Ther Oncolytics,2020,30;17:169-179.

PubMed: 32346607 ( click the link to review the publication )

Cell Chem Biol,2020,16;27(1):94-104.e5.

PubMed: 31902676 ( click the link to review the publication )

Cell Chem Biol,2020,20;27(2):197-205.e6.

PubMed: 31734178 ( click the link to review the publication )

Antimicrob Agents Chemother,2020,4;AAC.02523-19.

PubMed: 32366713 ( click the link to review the publication )

Eur J Immunol,2020,50(1):73-85

PubMed: 31621069 ( click the link to review the publication )

Toxicol Sci,2020,1;174(2):218-240.

PubMed: 32040181 ( click the link to review the publication )

Int J Mol Sci,2020,18;21(8):2825.

PubMed: 32325639 ( click the link to review the publication )

Sci Rep,2020,24;10(1):5318.

PubMed: 32210281 ( click the link to review the publication )

Int J Biol Sci,2020,25;16(11):1774-1784.

PubMed: 32398948 ( click the link to review the publication )

J Biol Chem,2020,27;jbc.RA120.012981.

PubMed: 32461254 ( click the link to review the publication )
BMC Plant Biol,2020,20(1):158

PubMed: 32293271 ( click the link to review the publication )

Breast Cancer Res Treat,2020,179(2):337-347.

PubMed: 31655920 ( click the link to review the publication )

Pancreas,2020,49(2):290-299

PubMed: 32011537 ( click the link to review the publication )

Drug Des Devel Ther,2020,24;14:745-755.

PubMed: 32158193 ( click the link to review the publication )

PLoS One,2020,15(1):e0228189

PubMed: 31999754 ( click the link to review the publication )

KAUST Repository,2020,doi:10.1101/2020.04.01.021089

PubMed: no ( click the link to review the publication )

J Allergy Clin Immunol,2020,21;S0091-6749(20)30259-1.

PubMed: 32088305 ( click the link to review the publication )

bioRxiv,2020,doi:10.1101/2020.05.26.117770

PubMed: No ( click the link to review the publication )

Genome Biol,2019,20(1):253

PubMed: 31771620 ( click the link to review the publication )

Nat Commun,2019,10(1):2197

PubMed: 31097693 ( click the link to review the publication )

Nat Commun,2019,10(1):5444

PubMed: 31784510 ( click the link to review the publication )

Sci Adv,2019,5(5):eaav2249

PubMed: 31106268 ( click the link to review the publication )

Sci Adv,2019,5(6):eaav9784

PubMed: 31249867 ( click the link to review the publication )

Clin Cancer Res,2019,25(14):4530-4541

PubMed: 30940655 ( click the link to review the publication )

Proc Natl Acad Sci U S A,2019,116(39):19541-19551

PubMed: 31501330 ( click the link to review the publication )

NPJ Genom Med,2019,4:7

PubMed: 30962949 ( click the link to review the publication )

Cell Rep,2019,5;26(6):1544-1556.e8.

PubMed: 30726737 ( click the link to review the publication )

Neuropsychopharmacology,2019,10.1038/s41386-018-0266-7

PubMed: 30518933 ( click the link to review the publication )

J Exp Clin Cancer Res,2019,38(1):56

PubMed: 30728057 ( click the link to review the publication )

Cancers (Basel),2019,30;11(2):156.

PubMed: 30704052 ( click the link to review the publication )

Breast Cancer Res,2019,21(1):77

PubMed: 31262335 ( click the link to review the publication )

Breast Cancer Res,2019,21(1):37

PubMed: 30845991 ( click the link to review the publication )

Development,2019,146(14)

PubMed: 31142539 ( click the link to review the publication )

Cell Chem Biol,2019,26(5):765-777

PubMed: 30956147 ( click the link to review the publication )
Cell Chem Biol,2019,21;26(2):235-243.e5.

PubMed: 30527999 ( click the link to review the publication )

ACS Infect Dis,2019,5(10):1764-1771

PubMed: 31434474 ( click the link to review the publication )

Neurobiol Aging,2019,76:24-34

PubMed: 30640040 ( click the link to review the publication )

Biochem Pharmacol,2019,169:113640

PubMed: 31536726 ( click the link to review the publication )

Sci Rep,2019,9(1):13308

PubMed: 31527768 ( click the link to review the publication )

Sci Rep,2019,9(1):16452

PubMed: 31712618 ( click the link to review the publication )

Cancer Gene Ther,2019,10.1038/s41417-019-0127-5

PubMed: 31383953 ( click the link to review the publication )

J Biol Chem,2019,294(47):17941-17950

PubMed: 31597699 ( click the link to review the publication )

J Biol Chem,2019,9;294(32):12146-12156.

PubMed: 31227523 ( click the link to review the publication )

Stem Cells Int,2019,2019:3435901

PubMed: 31871467 ( click the link to review the publication )

Biochem J,2019,476(21):3197-3209

PubMed: 31652302 ( click the link to review the publication )

Cancer Manag Res,2019,11:8391-8405

PubMed: 31571995 ( click the link to review the publication )

Breast Cancer Res Treat,2019,178(2):263-274

PubMed: 31388935 ( click the link to review the publication )

Breast Cancer Res Treat,2019,10.1007/s10549-019-05504-5

PubMed: 31784862 ( click the link to review the publication )

Acta Pharmacol Sin,2019,10.1038/s41401-019-0246-4

PubMed: 31197246 ( click the link to review the publication )

Cell Signal,2019,67:109508

PubMed: 31866490 ( click the link to review the publication )

Eur J Pharm Sci,2019,10.1016/j.ejps.2019.105088

PubMed: 31626963 ( click the link to review the publication )

Virology,2019,541:41-51

PubMed: 31826845 ( click the link to review the publication )

BMC Cancer,2019,19(1):936

PubMed: 31601188 ( click the link to review the publication )

Exp Gerontol,2019,126:110691

PubMed: 31421186 ( click the link to review the publication )

Int J Parasitol Drugs Drug Resist,2019,10:28-37.

PubMed: 31015150 ( click the link to review the publication )

J Bone Oncol,2019,19:100268

PubMed: 31832331 ( click the link to review the publication )

Anal Biochem,2019,569:46-52

PubMed: 30707898 ( click the link to review the publication )

J Med Virol,2019,91(8):1440-1447.

PubMed: 30900754 ( click the link to review the publication )
Bioengineered,2019,10(1):98-107

PubMed: 31023186 ( click the link to review the publication )

Kaohsiung J Med Sci,2019,10.1002/kjm2.12051

PubMed: 30896891 ( click the link to review the publication )

Methods Mol Biol,2019,1888:115-126

PubMed: 30519943 ( click the link to review the publication )

Methods Mol Biol,2019,1888:21-43

PubMed: 30519939 ( click the link to review the publication )

Nat Commun,2018,9(1):4728

PubMed: 30413706 ( click the link to review the publication )

Nat Commun,2018,9(1):1655

PubMed: 29695808 ( click the link to review the publication )

Clin Cancer Res,2018,15;24(24):6523-6535.

PubMed: 30194074 ( click the link to review the publication )

Cell Rep,2018,22(5):1185-1199

PubMed: 29386107 ( click the link to review the publication )

EBioMedicine,2018,28:80-89.

PubMed: 29396295 ( click the link to review the publication )

Mol Cancer Ther,2018,10.1158/1535-7163.MCT-18-0179

PubMed: 30523050 ( click the link to review the publication )

Stem Cell Res Ther,2018,9(1):319

PubMed: 30463599 ( click the link to review the publication )

Mol Pharm,2018,5;15(11):5410-5426.

PubMed: 30285456 ( click the link to review the publication )

Cancer Sci,2018,109(4):1220-1229

PubMed: 29453896 ( click the link to review the publication )

Antimicrob Agents Chemother,2018,10.1128/AAC.01744-18

PubMed: 30455231 ( click the link to review the publication )

Hum Gene Ther,2018,29(8):886-901

PubMed: 29641320 ( click the link to review the publication )

Sci Rep,2018,8(1):3521

PubMed: 29476067 ( click the link to review the publication )

Sci Rep,2018,8(1):14800

PubMed: 30287839 ( click the link to review the publication )

Sci Rep,2018,8(1):13106

PubMed: 30166612 ( click the link to review the publication )

Sci Rep,2018,21;8(1):14178.

PubMed: 30242186 ( click the link to review the publication )

J Cell Physiol,2018,233(1):422-433

PubMed: 28294327 ( click the link to review the publication )

Toxicol Lett,2018,291:138-148.

PubMed: 29655783 ( click the link to review the publication )

Cell Stress,2018,21;2(4):82-90.

PubMed: 31225471 ( click the link to review the publication )

Cell Stress,2018,10.15698/cst2018.04.131

PubMed: ( click the link to review the publication )

FEBS Open Bio,2018,9(1):82-91

PubMed: 30652076 ( click the link to review the publication )
Antiviral Res,2018,158:226-237

PubMed: 30149038 ( click the link to review the publication )

Oncotarget,2018,9(57):31018-31031

PubMed: 30123424 ( click the link to review the publication )

Methods Mol Biol,2018,1795:203-221.

PubMed: 29846930 ( click the link to review the publication )

Nat Commun,2017,8:15289

PubMed: 28474672 ( click the link to review the publication )

Nat Chem Biol,2017,13(6):616-623

PubMed: 28346404 ( click the link to review the publication )

Nat Commun,2017,17;8:16078.

PubMed: 28714472 ( click the link to review the publication )

Cell Rep,2017,21(9):2639-2646

PubMed: 29186697 ( click the link to review the publication )

Lab Chip,2017,31;17(3):511-520.

PubMed: 28092382 ( click the link to review the publication )

Cancer Lett,2017,405:73-78

PubMed: 28756008 ( click the link to review the publication )

Anal Chem,2017,89(12):6678-6685

PubMed: 28520400 ( click the link to review the publication )

J Mol Biol,2017,429(13):2042-2045

PubMed: 28137420 ( click the link to review the publication )

Biochim Biophys Acta,2017,1861(4):947-957

PubMed: 28161478 ( click the link to review the publication )

Antimicrob Agents Chemother,2017,62(1)

PubMed: 29061736 ( click the link to review the publication )

Biochem Pharmacol,2017,142:39-45

PubMed: 28647489 ( click the link to review the publication )

J Biol Chem,2017,292(41):17037-17045

PubMed: 28821610 ( click the link to review the publication )

Front Plant Sci,2017, 10.3389/fpls.2017.00852.

PubMed: 28603531 ( click the link to review the publication )

ChemMedChem,2017,12(22):1857-1865

PubMed: 28952188 ( click the link to review the publication )

PLoS One,2017,5;12(1):e0169407.

PubMed: 28056055 ( click the link to review the publication )

Biochem Biophys Res Commun,2017,493(1):58-63

PubMed: 28919416 ( click the link to review the publication )

SLAS Discov,2017,22(8):974-984.

PubMed: 28644734 ( click the link to review the publication )

Parasitol Res,2017,116(10):2619-2626.

PubMed: 28776226 ( click the link to review the publication )

Biol Pharm Bull,2017,40(8):1289-1298.

PubMed: 28769010 ( click the link to review the publication )

Oncotarget,2017,15;8(63):106382-106392.

PubMed: 29290956 ( click the link to review the publication )

J Neurosci,2016,27;36(30):7925-35.

PubMed: 27466337 ( click the link to review the publication )
Mol Cancer Ther,2016,15(3):412-20.

PubMed: 26721946 ( click the link to review the publication )

J Mol Cell Cardiol,2016,97:106-13

PubMed: 27130278 ( click the link to review the publication )

Pharmacol Res,2016,113(Pt A):216-227

PubMed: 27543462 ( click the link to review the publication )

ACS Chem Biol,2016,19;11(8):2195-205.

PubMed: 27227314 ( click the link to review the publication )

ACS Chem Biol,2016,17;11(6):1595-602.

PubMed: 26999302 ( click the link to review the publication )

Biogerontology,2016,17(5-6):907-920.

PubMed: 27484416 ( click the link to review the publication )

ChemMedChem,2016,10.1002/cmdc

PubMed: 27472906 ( click the link to review the publication )

ChemMedChem,2016,11(11):1137-44

PubMed: 27135311 ( click the link to review the publication )

Bioorg Med Chem,2016,24(19):4647-51

PubMed: 27519462 ( click the link to review the publication )

PLoS One,2016,11(2):e0149848

PubMed: 26919709 ( click the link to review the publication )

Sensors (Basel),2016,16(3)

PubMed: 26999137 ( click the link to review the publication )

Database (Oxford),2016,7;2016:baw041.

PubMed: 27055828 ( click the link to review the publication )

Genome Biol,2015,19;16(1):127.

PubMed: 26084335 ( click the link to review the publication )

Clin Cancer Res,2015,21(5):1172-82

PubMed: 25549722 ( click the link to review the publication )

Biosens Bioelectron,2015,68:699-704

PubMed: 25668591 ( click the link to review the publication )

J Control Release,2015,204:20-9

PubMed: 25681050 ( click the link to review the publication )

Oncogene,2015,34(32):4199-210

PubMed: 25362855 ( click the link to review the publication )

Cancer Discov,2015,5(2):154-67.

PubMed: 25501949 ( click the link to review the publication )

Mol Cancer Ther,2015,14(5):1213-23

PubMed: 25777964 ( click the link to review the publication )

Biochim Biophys Acta,2015,10.1016/j.bbapap.2015.04.023

PubMed: 25936777 ( click the link to review the publication )

Breast Cancer Res Treat,2015,149(3):715-26

PubMed: 25667100 ( click the link to review the publication )

Cell Cycle,2015,14(1):109-22

PubMed: 25602521 ( click the link to review the publication )

BMC Cancer,2015,15:239

PubMed: 25885472 ( click the link to review the publication )

PLoS One,2015,10(2):e0118346

PubMed: 25706943 ( click the link to review the publication )
PLoS One,2015,10(11):e0142655

PubMed: 26569102 ( click the link to review the publication )

Biochem Biophys Res Commun,2015,463(4):888-93

PubMed: 26056008 ( click the link to review the publication )

Comb Chem High Throughput Screen,2015,18(9):855-61.

PubMed: 26477352 ( click the link to review the publication )

Assay Drug Dev Technol,2015,13(10):638-49.

PubMed: 26192013 ( click the link to review the publication )

Oncotarget,2015,6(3):1531-43

PubMed: 25605238 ( click the link to review the publication )

Head Neck,2015,37(12):1722-32

PubMed: 24986420 ( click the link to review the publication )

Mol Cancer Ther,2014,13(2):353-63

PubMed: 24398428 ( click the link to review the publication )

Mol Cancer Res,2014,12(5):703-13

PubMed: 24554781 ( click the link to review the publication )

ACS Chem Biol,2014,9(5):1160-71

PubMed: 24568369 ( click the link to review the publication )

PLoS One,2014,9(7):e102741

PubMed: 25048812 ( click the link to review the publication )

Mol Med Rep,2014,10(6):3348-56

PubMed: 25323421 ( click the link to review the publication )

Mol Med Rep,2014,9(1):83-90.

PubMed: 24213221 ( click the link to review the publication )

Oncotarget,2014,5(15):6512-25

PubMed: 25156567 ( click the link to review the publication )

Curr Protoc Chem Biol,2014,4:177-191

PubMed: 26705509 ( click the link to review the publication )

PLoS One,2013,8(5):e63240

PubMed: 23667592 ( click the link to review the publication )

PLoS One,2013,8(4):e60334

PubMed: 23593196 ( click the link to review the publication )

Case Studies using Selleck Compound Libraries

Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):
Nature.2019;574(7777):268-272
Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):
Nat Commun. 2019 16;10(1):2197
Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):
Cell Res. 2019;29(9):739-753
Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):
Mov Disord. 2019;34(3):323-334
Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):
Blood. 2019 17;134(16):1323-1336
Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):
Cancer Immunol Res.2017;5(9):790-803

Description & Advantages

• A unique collection of 1461 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS)

• Targets kinases such as EGFR, PI3K, Aurora Kinase, CDK, and MEK

• Some inhibitors have been approved by the FDA

• Most are ATP competitive

• Structurally diverse, medicinally active, and cell permeable

• Rich documentation with structure and customer reviews

• NMR and HPLC validated to ensure high purity

Product Details

Formulation:	1402 compounds pre-dissolved in 10mM DMSO, 15 compounds pre-dissolved in 10mM water and 44 compounds pre-dissolved in 2mM DMSO
Container:	96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability:	12 months -20°C in DMSO
Stability:	24 months -80°C in DMSO
Shipping:	Blue ice or dry ice
Packaging:	Inert gas

Kinase Inhibitor Library Composition

HTS Facility Partners

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A unique collection of 135 nucleoside analogues used for high throughput screening(HTS) and high content screening(HCS).
Obesity Compound Library

A unique collection of 941 compounds used for research in obesity.
PI3K/Akt Inhibitor Library

A unique collection of 262 small molecule inhibitors used for PI3K/Akt/mTOR pathway research.
Protease Inhibitor Library

A unique collection of 227 small molecule inhibitors used for chemical genomics, high-throughput screening (HTS), and high content screening (HCS).
Protein-protein Interaction Inhibitor Library

A unique collection of 188 protein-protein Interaction(PPI) Inhibitors used for high throughput screening(HTS) and high content screening(HCS).
Pyroptosis Compound Library

A unique collection of 441 pyroptosis related compounds used for high throughput screening(HTS) and high content screening(HCS).
Small Molecule Immuno-Oncology Compound Library

A unique collection of 122 Immuno-Oncology small molecules used for oncotherapy in conjunction with other drugs.
Stem Cell Signaling Compound Library

A unique collection of 451 compounds with biological activity used for stem cell regulatory and signaling pathway research.
TGF-beta/Smad compound library

A unique collection of 105 small molecules with biological activity used for TGF-beta/Smad pathway research.
Tyrosine Kinase Inhibitor Library

A unique collection of 394 tyrosine kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).
Ubiquitination Compound Library

A unique collection of 151 small molecules for Ubiquitination related research.

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