Kinase Inhibitor Library

Catalog No.L1200

A unique collection of 1814 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).

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Kinase Inhibitor Library Contents

Description & Advantages

• A unique collection of 1814 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS)

• Targets kinases such as EGFR, PI3K, Aurora Kinase, CDK, and MEK

• Some inhibitors have been approved by the FDA

• Most are ATP competitive

• Structurally diverse, medicinally active, and cell permeable

• Rich documentation with structure and customer reviews

• NMR and HPLC validated to ensure high purity

Product Details

Formulation	1730 compounds pre-dissolved in 10mM DMSO, 30 compounds pre-dissolved in 10mM water, 53 compounds pre-dissolved in 2mM DMSO and 1 compound pre-dissolved in 2mM water
Container	96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability	12 months	-20°C	in DMSO
Stability	24 months	-80°C	in DMSO
Shipping	Blue ice or dry ice

Case Studies using Selleck Compound Libraries

Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

Nature.2019;574(7777):268-272
Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

Nat Commun. 2019 16;10(1):2197
Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

Cell Res. 2019;29(9):739-753
Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

Mov Disord. 2019;34(3):323-334
Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

Blood. 2019 17;134(16):1323-1336
Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

Cancer Immunol Res.2017;5(9):790-803

Kinase Inhibitor Library Composition

HTS Facility Partners