All Products

Catalog No. Product Name Information
S2251 (-)-Huperzine A (HupA) (-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4.
S4760 (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD, HP-β-cyclodextrin, Hydroxypropyl betadex, Hydroxypropyl-β-cyclodextrin), a well-known sugar used in drug delivery, genetic vector, environmental protection and treatment of Niemann-Pick disease type C1 (NPC1), is an inhibitor of amyloid-β aggregation.
S5902 1,2,3,4,5,6-Hexabromocyclohexane 1,2,3,4,5,6-Hexabromocyclohexane (NSC7908) is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation with IC50 value to be estimated in low micromolar range.
S4173 1-Hexadecanol 1-Hexadecanol is a fatty alcohol used to make other chemicals.
S6364 1-Hydroxy-2-naphthoic acid 1-Hydroxy-2-naphthoic acid is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms.
S3089 12-Hydroxydodecanoic acid

12-Hydroxydodecanoic acid (G12) is an active endogenous metabolite.

S4507 17-Hydroxyprogesterone 17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.
S5853 2'-Hydroxy-2-methoxychalcone 2'-Hydroxy-2-methoxychalcone is a chemical.
S5173 2'-Hydroxy-4'-methylacetophenone 2'-Hydroxy-4'-methylacetophenone may be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl)oxy]acetophenone and possesses acaricidal property.
S9375 2'-Hydroxyacetophenone 2'-Hydroxyacetophenone is a flavouring ingredient.
S0355 2-HBA 2-HBA is a potent inducer of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) and activates both caspase-3 and caspase-10.
S6198 2-Hexanone 2-Hexanone, a volatile organic compound, is used as a general solvent.
S6183 2-Hydroxy-2-methylbutanoic acid 2-Hydroxy-2-methylbutyric acid is an unusual metabolite found in the urine of patients with 2-hydroxyglutaric aciduria and maple syrup urine disease. 2-Hydroxy-2-methylbutyric acid is also a secondary metabolite found in human urine after exposure to the gasoline additive tert-amyl-Me-ether (TAME).
S6098 2-Hydroxy-3-methylbutanoic acid 2-Hydroxy-3-methylbutanoic acid (3-Methyl-2-hydroxybutyric acid, 2-Hydroxyisopentanoic acid, 2-Oxyisovaleric acid) is a metabolite found in the urine of patients with phenylketonuria, methylmalonic acidemia, propionic acidemia, 3-ketothiolase deficiency, isovaleric acidemia, 3-methylcrotonylglycemia, 3-hydroxy-3-methylglutaric acidemia, multiple carboxylase deficiency, glutaric aciduria, ornithine transcarbamylase deficiency, glyceroluria, tyrosinemia type I, galactosemia, and maple syrup urine disease.
S5562 2-Hydroxybenzyl alcohol 2-Hydroxybenzyl alcohol (Salicyl alcohol, Salicain, Diathesin, Saligenin, Saligenol, o-Methylolphenol, α,2-Toluenediol), which can be found in a number of food items such as red huckleberry, rye, jerusalem artichoke, and ceylon cinnamon, is precursor of salicylic acid and is formed from salicin by enzymatic hydrolysis by Salicyl-alcohol beta-D-glucosyltransferase or by acid hydrolysis.
E0025 2-Hydroxybenzylamine 2-Hydroxybenzylamine (2-(Aminomethyl)phenol, 2-HOBA, NSC 127870) is a naturally occurring compound found in buckwheat and is a selective scavenger of dicarbonyl electrophiles that protects proteins and lipids from being modified by these electrophiles. 2-HOBA reduces inflammation and plaque apoptotic cells and promotes efferocytosis and features of stable plaques. 2-HOBA has potential for use as a nutrition supplement due to its ability to protect against the damaging effects of oxidative stress.
S6119 2-Hydroxybutyric acid 2-Hydroxybutyric acid (α-hydroxybutyrate) is a chiral compound having two enantiomers, D-2-hydroxybutyric acid and L-2-hydroxybutyric acid. It is produced in mammalian tissues (principally hepatic) that catabolize L-threonine or synthesize glutathione.
S3323 2-Hydroxycaproic acid

2-Hydroxyhexanoic acid (2-Hydroxyhexanoic acid) is an endogenous metabolite.

S5436 2-Hydroxycaprylic acid 2-Hydroxycaprylic acid (2-hydroxyoctanoic acid) belongs to the class of organic compounds known as medium-chain fatty acids.
S6154 2-Hydroxyphenylacetic acid 2-Hydroxyphenylacetic acid (2-Hydroxybenzeneacetate, ortho-Hydroxyphenylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway styrene degradation.
S6360 2-Hydroxypyridine 2-Hydroxypyridine (2-Pyridino, 2-Pyridone) is used in peptide synthesis.
S2417 20-Hydroxyecdysone 20-Hydroxyecdysone (Ecdysterone, 20E, B-ecdysone, Commisterone, Crustecdysone) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods.20-Hydroxyecdysone (Ecdysterone, 20E) inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP.
S3260 3'-hydroxy Puerarin 3'-hydroxy Puerarin is an isoflavone isolated from Puerariae Lobatae Radix.
S3210 3'-Hydroxy-4'-methoxyacetophenone 3'-Hydroxy-4'-methoxyacetophenone (Acetoisovanillone, Isoacetovanillone, Diosmin EP Impurity A) is an active P. spinosa extract with anti-inflammatory potential.
S3940 3'-Hydroxypterostilbene 3'-Hydroxypterostilbene (3'-HPT) is one of the active constituents of Sphaerophysa salsula and Pterocarpus marsupium which may be useful in treating different types of haematological malignancies. 3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways.
S3339 3-(2-Hydroxyphenyl)propionic acid

3-(2-Hydroxyphenyl)propanoic acid (Melilotic acid, Melilotate, 2-hydroxybenzenepropanoic acid) is an endogenous metabolite.

S6074 3-(3-Hydroxyphenyl)propionic Acid 3-(3-Hydroxyphenyl)propionic acid (m-Hydroxyphenylpropionic acid, 3-Hydroxyhydrocinnamic acid) is one of the major metabolites of ingested caffeic acid and of the phenolic degradation products of proanthocyanidins by the microflora in the colon.
S3355 3-Hydroxyanthranilic acid

3-Hydroxyanthranilic Acid (3-HAA, 3-HANA), a tryptophan metabolite, has an immunomodulatory effect that may result from inhibition of PI3K/Akt/mTOR and NF-κB activity, thereby decreasing the production of pro-inflammatory mediators.

S3157 3-Hydroxybenzaldehyde

3-Hydroxybenzaldehyde (3-HBA), one of the benzaldehydes commonly found in nature, is produced by 3-hydroxybenzyl-alcohol dehydrogenase, and is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans (ALDH2). 3-Hydroxybenzaldehyde exhibits vasculoprotective effects.

S6367 3-Hydroxybenzoic acid 3-Hydroxybenzoic acid (m-Hydroxybenzoic acid, 3-Carboxyphenol, m-Salicylic acid) is used as an intermediate in the synthesis of plasticisers, resins, pharmaceuticals, etc.
S6363 3-Hydroxybenzyl alcohol 3-Hydroxybenzyl alcohol is used as an intermediate to produce other chemicals.
S1031 3-Hydroxybutyric acid 3-Hydroxybutyric acid (3-hydroxybutanoic acid, β-Hydroxybutyric acid, BHB) is a small molecule metabolite that is elevated in type I diabetes.
S5586 3-Hydroxycinnamic acid 3-hydroxycinnamic acid (meta-Coumaric acid, m-Coumaric acid, m-Coumarate) is an aromatic acid that can be found in vinegar.
S4790 3-Hydroxyflavone 3-Hydroxyflavone (Flavon-3-ol, 3-HF, 3-Hydroxy-2-phenylchromone) is the simplest molecule of the flavonol class that is usually used in synthesis of biologically active molecules.
S6124 3-Hydroxyisovaleric acid 3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine.
S3364 3-Hydroxyphenylacetic acid

3-Hydroxyphenylacetic acid (3-HPAA) is a phenolic acid mostly found in olive oil wastewater and an intestinal metabolite of the dietary flavonoid quercetin. 3-Hydroxyphenylacetic acid exhibits antimicrobial properties.

S6252 3-Hydroxypicolinic acid 3-Hydroxy picolinic acid is a picolinic acid derivative and is a member of the pyridine family. It is used as a matrix for nucleotides in MALDI mass spectrometry analyses
S4937 4'-Hydroxychalcone 4'-Hydroxychalcone (P-Cinnamoylphenol), found in herbs and spices and tea, is a member of the class of compounds known as retrochalcones. It has diverse biological activities, inhibiting TNFα-induced NF-κB pathway activation in a dose-dependent manner and activating BMP signaling.
S5396 4'-Hydroxypropiophenone 4'-Hydroxypropiophenone (Paroxypropione, p-hydroxypropiophenone) is a member of acetophenones.
S5178 4-Hydroxy-2,5-dimethyl-3(2H)furanone 4-Hydroxy-2,5-dimethyl-3(2H)furanone (furaneol, HDMF) is a naturally occurring substance found in a variety of fruits and has been shown to have antimicrobial activity.
S4942 4-Hydroxy-3,5-dimethoxybenzyl alcohol 4-Hydroxy-3,5-dimethoxybenzyl alcohol (Syringic alcohol, Syringyl alcohol) is a kind of phenol with antiviral properties.
S6297 4-Hydroxy-3-methylbenzoic acid 4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a healthy population.
S3754 4-Hydroxybenzoic acid 4-Hydroxybenzoic acid (p-hydroxybenzoic acid, PHBA, para-Hydroxybenzoic acid, 4-hydroxybenzoate), also known as p-hydroxybenzoic acid (PHBA), is a phenolic derivative of benzoic acid and widely used in organic synthesis. It is the most widely distributed aromatic organic acid in the vegetable kingdom.
S3857 4-Hydroxybenzyl alcohol 4-hydroxybenzyl alcohol (P-Methylolphenol, 4-Methylolphenol), an important phenolic constituent of Gastrodia elata Blume (GEB), has been shown to have many beneficial effects in different animal models of neurological disorders, such as, headaches, convulsive behavior, dizziness, and vertigo.
S4763 4-Hydroxychalcone 4-Hydroxychalcone (P-Cinnamoylphenol) is a chalcone metabolite with diverse biological activities. It inhibits TNFα-induced NF-κB pathway activation in a dose-dependent manner and also activates BMP signaling.
S9793 4-Hydroxynonenal

4-Hydroxynonenal (4-HNE, HNE, 4-hydroxy Nonenal, 4-hydroxy-2-nonenal) is one of the major end products of lipid peroxidation and has been widely accepted as an inducer of oxidative stress.

S4863 4-Hydroxyphenylacetic acid 4-Hydroxyphenylacetic acid (p-Hydroxyphenylacetic acid, parahydroxy phenylacetate), a chemical compound found in olive oil and beer, is an intermediate used to synthesize atenolol and 3,4-dihydroxyphenylacetic acid. 4-hydroxyphenylacetic acid is an inducer of Nrf2 expression.
S2995 4-Hydroxyphenylpyruvic acid 4-Hydroxyphenylpyruvic acid (4-HPPA), an abundant colon metabolite of polyphenols, is a potent scavenger that suppresses levels of free radicals and cyclooxygenase-2 (COX-2) and contributes to reduced risk of colon cancer development.
S9360 4-Hydroxyquinazoline 4-Hydroxyquinazoline (Quinazolin-4-ol, 4-Quinazolinol) is a PARP inhibitor with a high potency for PARP-1 with IC50 of 9.5 μM.
S7827 4-Hydroxytamoxifen (Afimoxifene) 4-Hydroxytamoxifen (Afimoxifene) is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. It activates on-target modification frequency for intein-Cas9 variants.
S3316 5-Hydroxy-1-tetralone

5-hydroxy-1-tetralone is a fluorescent labeling reagent for the determination of glycosphingolipid from small amounts of biological samples.

S2659 5-hydroxymethyl Tolterodine (PNU 200577, 5-HMT, 5-HM) 5-hydroxymethyl tolterodine (PNU 200577) is a new muscarinic receptor antagonist with Kb of 0.84 nM.
S6081 5-Hydroxymethyl-2-furancarboxylic acid 5-Hydroxymethyl-2-furancarboxylic acid is the main metabolite of 5-hydroxymethyl-2-furfural, a product of acid-catalyzed degradation of sugars during the heating and storage of foods that influences taste and physiological functions in the body.
E0027 5-Hydroxymethylcytosine 5-Hydroxymethylcytosine (5hmC) is a naturally existing component in mammalian genomic DNA and is regarded as the sixth DNA base. 5-Hydroxymethylcytosine is an intermediate metabolite in active DNA demethylation. 5-Hydroxymethylcytosine is epigenetic marks known to affect global gene expression in mammals.
S3772 5-Hydroxymethylfurfural 5-Hydroxymethylfurfural (5-HMF) is an important bio-sourced intermediate, formed from carbohydrates such as glucose or fructose and used for production of fuels and chemical intermediates.
S6127 5-Hydroxymethyluracil 5-Hydroxymethyluracil (5hmU) is a thymine base modification found in the genomic DNA of diverse organisms ranging from bacteriophages to mammals
S2374 5-hydroxytryptophan (5-HTP) 5-Hydroxytryptophan (5-HTP, NSC-92523), also known as oxitriptan (INN), is a naturally occurring amino acid and chemical precursor for the treatment of depression.
S9330 6-Hydroxy-4-methylcoumarin 6-Hydroxy-4-methylcoumarin is a chemical.
S3315 6-Hydroxyindole

6-Hydroxyindole (1H-indol-6-ol) is an endogenous potent and long-lasting OATP1B1 inhibitor with IC50 of ~10 μM.

S6285 6-Hydroxynicotinic acid 6-Hydroxynicotinic acid is widely used in the manufacture of industrial products.
S7330 6H05 6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C).
S5548 7-Hydroxy-4-chromone 7-Hydroxychromone is an inhibitor of Src kinase with IC50 of <300 μM.
S9331 7-Hydroxy-4-methyl-8-nitrocoumarin 7-Hydroxy-4-methyl-8-nitrocoumarin is a chemical.
S3936 7-Hydroxycarbostyril 7-Hydroxycarbostyril (3,4-Dihydro-7-hydroxycarbostyril) is a kind of pharmaceutical intermediate.
S3920 7β-Hydroxylathyrol 7β-Hydroxylathyrol (7beta-Hydroxylathyrol, 7-Hydroxylathyrol) is natural occuring product extracted from the seeds of Euphorbia lathyris L.
S4547 8-Hydroxyquinoline 8-Hydroxyquinoline (8-Oxychinolin, 8-Quinolinol, Oxine) is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes.
S1582 H 89 2HCl H 89 2HCl is a potent PKA inhibitor with Ki of 48 nM in a cell-free assay, 10-fold selective for PKA than PKG,500-fold greater selectivity than PKC, MLCK, calmodulin kinase II and casein kinase I/II. H 89 2HCl induces autophagy.
S6214 H-1152 dihydrochloride H-1152 dihydrochloride (2HCl) is a membrane-permeable and selective inhibitor of Rho-associated protein kinase (ROCK). H-1152 inhibits ROCK2, PKA, PKC, PKG, AuroraA and CaMK2 with IC50 of 0.0120 μM, 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
S6652 H-151 H-151 is a highly potent and covalent antagonist of STING that has noteworthy inhibitory activity both in human cells and in vivo.
S6203 H-Abu-OH H-Abu-OH (2-Aminobutyric acid, 2-Aminobutanoic acid, Homoalanine, α-Aminobutanoic acid, Ethylglycine) is a non-proteinogenic alpha amino acid that is used by nonribosomal peptide synthases.
S5522 H-Cys(Trt)-OH H-Cys(Trt)-OH (L-Cys(Trt)-OH, H-L-Cys(Trt)-OH, S-Tritylcysteine) is a specific inhibitor of Eg5 that inhibits Eg5-driven microtubule sliding velocity in a reversible fashion with an IC50 of 500 nM.
S6253 H-D-Trp-OH H-D-Trp-OH (D-Tryptophan) is the D-enantiomer of tryptophan, which is an essential amino acid in the human diet.
S6133 H-Gly-Pro-OH H-Gly-Pro-OH (Glycyl proline, Glycyl-L-proline) is a dipeptide composed of glycine and proline, and is an end product of collagen metabolism that is further cleaved by prolidase. The resulting proline molecules are recycled into collagen or other proteins.
S6109 H-HoArg-OH H-HoArg-OH (L-Homoarginine) is an organ-specific, uncompetitive inhibitor of serum "bone and liver" alkaline phosphatase.
S6093 H-Phe-Phe-OH H-Phe-Phe-OH (Phenylalanyl-phenylalanine, Phe-Phe, L-Phe-L-Phe) is a short peptide diphenylalanine with utility for potential applications in biomaterial chemistry, sensors and bioelectronics.
S6044 H-Tyr(3-I)-OH H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) is responsible for catalyzing the first step of the noradrenergic biosynthesis pathway. H-Tyr(3-I)-OH is an effective tyrosine hydroxylase inhibitor.
S9687 H2DCFDA H2DCFDA (DCFH-DA, 2',7'-Dichlorodihydrofluorescein diacetate) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) production.
S3244 H3B-120 H3B-120 is a competitive, selective and allosteric inhibitor of carbamoyl phosphate synthetase 1 (CPS1) with IC50 of 1.5 μM and Ki of 1.4 μM. H3B-120 exhibits anti-tumor activity.
S8746 H3B-5942 H3B-5942 is a selective and irreversible estrogen receptor covalent antagonist, inactivates both ERα WT and ERα mutation. The Ki values are 1 nM and 0.41 nM, respectively.
S8675 H3B-6527 H3B-6527 is a highly selective covalent FGFR4 inhibitor with an IC50 value of <1.2 nM and at least 250-fold selectivity over FGFR1-3 (IC50 values of 320, 1,290 and 1,060 nM respectively).
S2964 HA-100 dihydrochloride HA-100 dihydrochloride is an inhibitor of cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase with IC50 of 4 μM, 8 μM, 12 μM and 240 μM, respectively.
S1071 HA14-1 HA14-1 is a non-peptidic ligand of a Bcl-2 surface pocket with IC50 of ~9 μM.
S8299 HA15 HA15 is a molecule that targets specifically HSPA5 (Heat shock 70kDa protein 5) also known as BiP (Immunoglobulin heavy-chain-binding protein) or Grp78 (glucose-regulated protein 78). HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
S3421 HA155 HA155 (Autotaxin Inhibitor IV), a boronic acid-based compound, inhibits autotaxin with IC50 of 5.7 nM by selectively binding to its catalytic threonine.
S6440 Halazone Halazone (Pantocide, p-sulfondichloramidobenzoic acid) is widely used to disinfect drinking water.
S4098 Halcinonide Halcinonide is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.
S4089 Halobetasol Propionate Halobetasol Propionate (BMY-30056, CGP-14458) is an anti-inflammatory and a dermatologic agent commonly used to treat psoriasis. Halobetasol propionate is thought to act by the induction of phospholipase A2 (PLA2) inhibitory proteins.
S8144 Halofuginone Halofuginone (RU-19110) is the competitively inhibitor of prolyl-tRNA synthetase with Ki of 18.3 nM.It could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in mammal.
S1920 Haloperidol Haloperidol (Haldol) is an antipsychotic and butyrophenone.
S4570 Halothane Halothane (Narcotane) is a general inhalation anesthetic used for induction and maintenance of general anesthesia.
S0148 HAMNO HAMNO (NSC-111847) is a potent and selective replication protein A (RPA) inhibitor with anti-tumor activity. HAMNO inhibits both ATR autophosphorylation and phosphorylation of RPA32 Ser33 by ATR.
A5246 HAPLN1 Rabbit Recombinant mAb HAPLN1 Rabbit Recombinant mAb detects endogenous level of HAPLN1.
S4776 Harmaline Harmaline, a natural occurrence β-carboline alkaloid, is a central nervous system stimulant and an acetylcholinesterase (AChR) inhibitor; also inhibits histamine N-methyltransferase.
E0009 Harmane Harmane (Harman, Aribine, Aribin, Locuturine, Locuturin, Loturine, Passiflorin, 1-Methylnorharman, NSC 54439) is a common compound in several foods, plants and beverages. Harmane is a selective monoamine oxidase inhibitors with IC50s of 0.5 μM and 5 μM for human MAO A and MAO B, respectively. Harmane also inhibits the apurinic/apyrimidinic (AP) endonuclease activity of the UV endonuclease induced by phage T4.
S3868 Harmine Harmine (Telepathine) is an alkaloid of the β-carboline family that regulates PPARγ expression through inhibition of the Wnt signaling pathway. It also selectively binds to MAO-A and reversibly inhibits monoamine oxidase A (MAO-A) but not the variant MAO-B.
S3817 Harmine hydrochloride Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs) and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.
S9171 Harpagoside Harpagoside, a natural product found in the plant Harpagophytum procumbens, has potent anti-rheumatic, anti-inflammatory and analgesic effects.
S9063 Harringtonine Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.
A5472 HB9/HLXB9 Rabbit Recombinant mAb HB9/HLXB9 Rabbit Recombinant mAb detects endogenous level of total HB9/HLXB9.
E0078 HBC 530 HBC 530 is an RNA mimic of GFP fluorophore for imaging in live cells and activated by binding to Pepper aptamers.
S0834 HBC514 HBC514 is a nonfluorescent HBC-analog but emits strong green fluorescence when it forms a tight complex with Pepper RNA aptamer thus enables visualization of RNAs. The fluorescences can be altered flexibly by simple washing and staining in living Pepper-tagged cells.
S6883 HBX 19818 HBX19818 is a specific inhibitor of USP7 with an IC 50 of 28.1 μM.
S2918 HC-030031 HC-030031 (TOSLAB 829227) is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively.
S6637 HC-067047 HC-067047 is a selective TRPV4 channel antagonist with IC50 values of 48 nM,133 nM,and 17 nM for human, rat, and mouse TRPV4 orthologs,respectively.
S0547 HCH6-1 HCH6-1 is a selective competitive antagonist of formyl peptide receptor 1 (FPR1) and has protective effects against acute lung injury (ALI). HCH6-1 may have potential as a new therapeutic agent for treating FPR1-involved inflammatory lung diseases.
A5723 HDAC1 Rabbit Recombinant mAb HDAC1 Rabbit Recombinant mAb detects endogenous levels of total HDAC1.
A5169 HDAC11 Rabbit Recombinant mAb HDAC11 Rabbit Recombinant mAb detects endogenous level of HDAC11.
A5132 HDAC7 Rabbit Recombinant mAb HDAC7 Rabbit Recombinant mAb detects endogenous level of total HDAC7.
A5195 HDAC8 Rabbit Recombinant mAb HDAC8 Rabbit Recombinant mAb detects endogenous level of total HDAC8.
S0746 hDHODH-IN-1 hDHODH-IN-1 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with anti-inflammatory effect.
S8606 HDM201 (Siremadlin) HDM201 (Siremadlin, NVP-HDM201) is a novel, highly potent and selective inhibitor of the p53-Mdm2 interaction with affinity constant for Mdm2 in the picomolar range and a selectivity ratio greater than 10000-fold vs Mdm4.
A5413 HEC1 Rabbit Recombinant mAb HEC1 Rabbit Recombinant mAb detects endogenous level of total HEC1.
S5336 Hecogenin Hecogenin (Hocogenin), a steroid saponin isolated from Agave sisalana, is a potent and highly selective inhibitor of UGT1A4 with an IC50 value of 1.5 μM.
S6373 Hecogenin acetate Hecogenin acetate, a steroidal sapogenin-acetylated with anti-inflammatory and antinociceptive, shows potential antihyperalgesic activity, inhibiting descending pain and acting in opioid receptors.
S3919 Hederacoside C Hederacoside C (HDC, Kalopanaxsaponin B) is one of the active ingredients in Hedera helix leaf extract (Ivy Ex.) and used to treat respiratory disorders.
S3899 Hederagenin Hederagenin (Caulosapogenin, Hederagenol, Hederagenic acid, Astrantiagenin E) is a highly water insoluble triterpenoid compound that can be found in various plants including Hedera helix and Chenopodium quinoa. It exhibits a variety of biological activities, including potent antitumor properties both in vitro and in vivo. Hederagenin inhibits LPS-stimulated expression of iNOS, COX-2, and NF-κB.
S4965 Helecin Helecin (Helicin) is the O-glucoside of salicylaldehyde, which is a key precursor to a variety chelating agents.
S3797 Helicide Helicide (4-formylphenyl-O-β-d-allopyranoside), a main active constituent from seeds of the Chinese herb Helicia nilagirica, has been reported to exert a sedative, analgesic and hypnotic effect, and is used clinically to treat neurasthenic syndrome, vascular headaches and trigeminal neuralgia.
S2384 Hematoxylin Hematoxylin (Hydroxybrazilin) is a compound that forms strongly colored complexes with certain metal ions, notably Fe(III) and Al(III) salts and a kind of stain in histology.
S5645 Hemin Hemin (protohemin) is an iron-containing porphyrin used in the management of porphyria attacks, particularly in acute intermittent porphyria.Hemin is an Heme oxygenase (HO)-1 inducer.
S5992 Heparan Sulfate Heparan sulfate (HS, Heparitin sulfate, Alpha-idosane, HHS 5, N-Acetylheparan Sulfate, Suleparoid, Tavidan), a constituent of HS proteoglycans (HSPGs), is a linear polysaccharide present on the cell surface. Heparan sulfate influences the binding affinity of intestinal epithelium cells (IECs) to Wnt, thereby promoting activation of canonical Wnt signaling and facilitating regeneration of small intestinal crypts after epithelial injury.
S1346 Heparin sodium Heparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins. Heparin is used as an anticoagulant primarily through its interaction with AT III by enhancing AT-IIImediated inhibition of blood coagulation factors, including thrombin and factor Xa. Heparin prevents the induction of autophagy.
S6831 HEPES HEPES is a zwitterionic sulfonic acid buffering agent, commonly used to uphold a neutral pH of basal medium within cell cultures.
E0380 Hepln-13

Hepln-13 is a potent and orally active Hepsin inhibitor with an IC50 of 0.33 µM.

S3336 Heptadecanoic acid

Heptadecanoic acid (C17:0), an odd chain saturated fatty acid, significantly inhibits cell proliferation, and migration, while promoting apoptosis in PC‑9 and PC‑9/GR cells. Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis.

S1697 Heptaethylene glycol Heptaethylene glycol (HO-PEG7-OH) is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
S3389 Heptamidine Dimethanesulfonate Heptamidine (SBi4211) Dimethanesulfonate is a novel and potent Pentamidine-related inhibitor of the calcium-binding protein S100B with a Kd of 6.9 μM.
E0208 Herbacetin

Herbacetin is a natural flavonoid compound found in flaxseed with strong antioxidant, antitumor and anti-inflammatory activity.

S1529 Hesperadin Hesperadin potently inhibits Aurora B with IC50 of 250 nM in a cell-free assay. It markedly reduces the activity of AMPK, Lck, MKK1, MAPKAP-K1, CHK1 and PHK while it does not inhibit MKK1 activity in vivo.
S2308 Hesperetin Hesperetin is a bioflavonoid and, to be more specific, a flavanone.
S2309 Hesperidin Hesperidin (Cirantin) is a flavanone glycoside found abundantly in citrus fruits.
S6426 Hesperidin methylchalcone Hesperidin methylchalcone is the Citrus original products with powerful antioxidant activity.
S0969 Heterophyllin B Heterophyllin B, an active cyclic peptide isolated from Pseudostellaria heterophylla, exhibits anti-tumor activity against esophageal cancer.
E0029 Hexa-D-arginine

Hexa-D-arginine is a potent and specific furin inhibitor with Ki values of 106 nM, 580 nM, and 13.2 μm for furin, PACE4, and PC1, respectively.

S4632 Hexachlorophene Hexachlorophene (Hexachlorofen, Fostril, Nabac, pHisoHex) is a potent KCNQ1/KCNE1 potassium channel activator with EC50 of 4.61 ± 1.29 μM; It can also attenuate Wnt/beta-catenin signaling through the Siah-1-mediated beta-catenin degradation.
S6147 Hexadecanedioic acid Hexadecanedioic acid (Thapsic acid, Hexadecanedioate, Palmitic acid) is a common saturated fatty acid found in animals, plants and microorganisms. It has antitumor activity.
S1804 Hexaethylene glycol Hexaethylene glycol is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
S1812 Hexaethylene glycol monomethyl ether Hexaethylene glycol monomethyl ether is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
S4069 Hexamethonium Dibromide Hexamethonium Dibromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia.
E0160 Hexaminolevulinate hydrochloride

Hexaminolevulinate hydrochloride (5-Aminolevulinic acid hexyl ester hydrochloride) is a tumour photosensitizer.

S1758 Hexane-1,6-diyldiphosphonic acid Hexane-1,6-diyldiphosphonic acid is an alkyl chain-based PROTAC linker that is applicable to the synthesis of PROTACs.
S2473 Hexestrol Hexestrol (Bibenzyl) binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.
S6408 Hexetidine Hexetidine is an anti-bacterial and anti-fungal agent with local anesthetic, astringent, deodorant and antiplaque activity.
A5225 Hexokinase 1 Rabbit Recombinant mAb Hexokinase 1 Rabbit Recombinant mAb detects endogenous level of total Hexokinase 1.
S3588 Hexylene glycol Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics. Hexylene glycol exhibits antibacterial and antifungal properties.
S4571 Hexylresorcinol Hexylresorcinol (4-Hexylresorcinol) is an organic compound with local anaesthetic, antiseptic and anthelmintic properties, is a potent inhibitor of mushroom tyrosinase. The IC50 values of hexylresorcinol for monophenolase is 1.24 μM and for diphenolase is 0.85 μM.
S2948 HG-10-102-01 HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant with IC50 of 23.3 nM and 3.2 nM, respectively.
S6513 HG-14-10-04 HG-14-10-04 is an inhibitor of ALK.
S8393 HG-9-91-01 HG-9-91-01 (SIK inhibitor 1) is a potent and highly selective inhibitor of salt-inducible kinase (SIK) with IC50 of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3, respectively.
S6882 HI-TOPK-032 HI-TOPK-032 is a potent and specific inhibitor of TOPK. HI-TOPK-032 also reduces ERK-RSK phosphorylation, regulates of the abundance of p53, cleaved caspase-7, and cleaved PARP, and induces apoptosis in cancer cells.
S0950 Hibifolin Hibifolin (Gossypetin-8-O-β-D-glucuronide) is a flavonol glycoside and acts as a potential inhibitor of adenosine deaminase (ADA) with a Ki of 49.92 μM. Hibifolin prevents β-amyloid-induced neurotoxicity in cultured cortical neurons.
L6100 HIF-1 Signaling Pathway Compound Library A unique collection of 444 HIF-1 signaling pathway compounds used for oxygen sensing related research.
S2850 HIF-2α-IN-2 HIF-2α-IN-2 is an inhibitor of hypoxia-inducible factors (HIF-2α) with IC50 of 16 nM in scintillation proximity assay (SPA).
S3960 Higenamine hydrochloride Higenamine (Norcoclaurine, (+-)-Demethylcoclaurine), also known as Norcoclaurine HCl, is a non-selective β2 adrenoceptor agonist which is a chemical compound naturally occurring in a number of plants.
L3500 Highly Selective Inhibitor Library A unique collection of 462 validated highly selective inhibitors with covering over 123 targets.
E0216 Hinokiflavone

Hinokiflavone, isolated from Selaginella P. Beauv, Juniperus phoenicea and Rhus succedanea, possesses excellent pharmacological activities, including anti-inflammatory, antioxidant and antitumor activity. Hinokiflavone induces apoptosis and inhibits migration of breast cancer cells via EMT signalling pathway.

S5618 Hippuric acid Hippuric Acid (2-Benzamidoacetic acid, Benzoylglycine) is an acyl glycine produced by the conjugation of benzoic acid and glycine, found as a normal component in urine as a metabolite of aromatic compounds from food.
E0067 Hispidin

Hispidin is a phenolic compound from Phellinus linteus and has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties.

S0248 Hispidol Hispidol ((Z)-Hispidol) is an inhibitor of TNF-α induced adhesion of monocytes to colon epithelial cells with IC50 of 0.50 µM. Hispidol is a potential therapeutic for inflammatory bowel disease.
S3296 Hispidulin Hispidulin (Dinatin), an active natrual ingredient in a number of traditional Chinese medicinal herbs, exhibits inhibitory activity against the oncogenic protein kinase Pim-1 with IC50 of 2.71 μM. Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells. Hispidulin exerts anti-osteoporotic and bone resorption attenuating effects via activating the AMPK signaling pathway.
S3968 Histamine Histamine, an organic nitrogenous compound, is involved in local immune responses regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. It is a potent H1 and H2 receptor agonist.
S4118 Histamine 2HCl Histamine is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2.
S4117 Histamine Phosphate Histamine acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors.
A5222 Histone H2A (acetyl K9) Rabbit Recombinant mAb Histone H2A (acetyl K9) Rabbit Recombinant mAb detects endogenous level of total Histone H2A (acetyl K9).
A5325 Histone H2A.Z Rabbit Recombinant mAb Histone H2A.Z Rabbit Recombinant mAb detects endogenous level of total Histone H2A.Z.
A5102 Histone H3 (acetyl K14) Rabbit Recombinant mAb

Histone H3 (acetyl K14) Rabbit Recombinant mAb detects endogenous levels of total Histone H3 (acetyl K14).

A5223 Histone H3 (mono methyl K36) Rabbit Recombinant mAb Histone H3 (mono methyl K36) Rabbit Recombinant mAb detects endogenous level of total Histone H3 (mono methyl K36).
A5060 Histone H3 (mono methyl R2) Rabbit Recombinant mAb

Histone H3 (mono methyl R2) Rabbit Recombinant mAb detects endogenous levels of total Histone H3 (mono methyl R2).

A5059 Histone H4 (mono methyl K16) Rabbit Recombinant mAb

Histone H4 (mono methyl K16) Rabbit Recombinant mAb detects endogenous levels of total Histone H4 (mono methyl K16).

L4900 Histone modification compound library A unique collection of 245 small molecule compounds with biological activity used for histone modification research and associated assays.
S1161 Histone Acetyltransferase Inhibitor II

Histone Acetyltransferase Inhibitor II (HAT Inhibitor II, compound 2c) is a potent, selective and cell-permeable p300 histone acetyltransferase (HAT) inhibitor with IC50 of 5 μM. Histone Acetyltransferase Inhibitor II shows anti-acetylase activity in mammalian cells.

S0837 HJC0197 HJC0197 is a selective Epac 1/2 dual antagonists with an IC50 of 5.9 μM for Epac2.
S8963 HLM006474 HLM006474 is a small molecule pan-E2F inhibitor that inhibits DNA binding to E2F4 with IC50 of 29.8 µM in A375 cells. HLM006474 induces a reduction in cell proliferation and an increase in apoptosis. The CDK/Rb/E2F pathway is commonly disrupted in lung cancer, and HLM006474 is shown to have efficacy in lung cancer.
S9892 HM43239

HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s' of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM, 1.8 nM and 1.0 nM, respectively.

A5451 HMGCR Rabbit Recombinant mAb HMGCR Rabbit Recombinant mAb detects endogenous level of total HMGCR.
S0288 HMN-154 HMN-154 is a novel benzenesulfonamide anticancer compound that inhibits KB and colon38 cells with IC50 of 2.6 ng/mL and 3 ng/mL, respectively.
S5807 HMN-176 HMN-176 is an active metabolite of HMN-214, which has a potent antitumor activity in mouse xenograft models. HMN-176 effectively inhibits PLK-1 by interference with its normal subcellular spatial distribution at centrosomes and along the cytoskeletal structure.
S1485 HMN-214 HMN-214 is a prodrug of HMN-176, which alters the cellular spatial orientation of Plk1.
A5314 hnRNP A1 Rabbit Recombinant mAb hnRNP A1 Rabbit Recombinant mAb detects endogenous level of total hnRNP A1.
A5334 hnRNP C1/C2 Rabbit Recombinant mAb hnRNP C1/C2 Rabbit Recombinant mAb detects endogenous level of total hnRNP C1/C2.
A5275 hnRNP K Rabbit Recombinant mAb hnRNP K Rabbit Recombinant mAb detects endogenous level of total hnRNP K.
S7501 HO-3867 HO-3867, an analog of curcumin, is a selective STAT3 inhibitor that inhibits its phosphorylation, transcription, and DNA binding without affecting the expression of other active STATs. HO-3867 induces apoptosis.
S1860 HO-PEG13-OH HO-PEG13-OH is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
S1948 HO-PEG14-OH HO-PEG14-OH is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
S5886 Hodostin Hodostin (Neostigmine methyl sulfate, Syntostigmin, Neostigmeth) is a reversible inhibitor of acetylcholinesterase (AChE), but can not cross the blood-brain barrier. It is used in the treatment of myasthenia gravis.
S0485 Hoechst 33342 Hoechst 33342 (Pibenzimol, bisBenzimide H 33342, HOE 33342, HO342) is a membrane-permeant fluorescent stain that can stain live cells. Hoechst 33342 binds to adenine-thymine-rich regions of DNA in the minor groove.
S0486 Hoechst 34580 Hoechst 34580 (HOE 34580) is a cell-permeable blue fluorescent dye to stain DNA and nuclei. Hoechst 34580 is also a good candidate for treating the Alzheimer's disease by inhibiting amyloid beta (Aβ) formation with IC50 of 0.86 μM.
S6396 HOIPIN-1 HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM for inhibiting the in vitro linear ubiquitination activity of the petit-LUBAC.
S4025 Homatropine Bromide Homatropine Bromide is an muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.
S4024 Homatropine Methylbromide Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.
S2881 Homo-PROTAC cereblon degrader 1 Homo-PROTAC cereblon degrader 1 (OUN20985) is a potent and efficient cereblon (CRBN) degrader with minimal effects on IKZF1 and IKZF3.
S9352 Homogentisic Acid Homogentisic Acid (Melanic acid, 2,5-dihydroxyphenylacetic acid) is found in Arbutus unedo (strawberry-tree) honey or present in the bacterial plant pathogen Xanthomonas campestris pv. phaseoli as well as in the yeast Yarrowia lipolytica.
S9015 Homoharringtonine (CGX-635) Homoharringtonine (CGX-635, Omacetaxine mepesuccinate, HHT, Myelostat, NSC 141633), a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression.
S9248 Homoorientin Homoorientin (Isoorientin, Luteolin-6-C-glucoside) is a flavone that acts as a radical scavenger and an antineoplastic agent.
S9417 Homoplantaginin Homoplantaginin (Hispidulin-7-glucoside), a main flavonoid from a traditional Chinese medicine Salvia plebeia, has anti-inflammatory and anti-oxidant properties. Homoplantaginin inhibits TNF-α and IL-6 mRNA expression, IKKβ and NF-κB phosphorylation.
S4572 Homosalate Homosalate (HMS, Homomenthyl salicylate) is an organic ultraviolet filter used in most sunscreens but has been reported to be toxic to marine organisms. Homosalate aggravates the invasion of human trophoblast cells as well as regulates intracellular signaling pathways including PI3K/AKT and MAPK pathways.
S5131 Homotaurine Homotaurine (Tramiprosate, Alzhemed, 3-Amino-1-propanesulfonic acid) is a synthetic organic compound that has GABAergic activity by mimicking GABA. It is a GABAA partial agonist as well as a GABAB receptor partial agonist with low efficacy.
S5642 Homovanillic acid Homovanillic acid (Vanillacetic acid) is a major catecholamine metabolite that is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain.
S3961 Homoveratrumic acid Homoveratrumic acid (Homoveratric acid) is the main metabolite of 3,4-dimethoxyphenylethylamine (DMPEA) in urine.
S2310 Honokiol (NSC 293100) Honokiol (NSC 293100) is the active principle of magnolia extract that inhibits Akt-phosphorylation and promotes ERK1/2 phosphorylation. Honokiol causes G0/G1 phase arrest, induces apoptosis, and autophagy via the ROS/ERK1/2 signaling pathway. Honokiol inhibits hepatitis C virus (HCV) infection. Phase 3.
S2385 Hordenine Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.
S3297 Hosenkoside A Hosenkoside A is a bioactive baccharane glycoside isolated from the seeds of impatiens balsamina.
S3276 Hosenkoside K Hosenkoside K is a bioactive baccharane glycoside isolated from the seeds of impatiens balsamina.
S0192 HPGDS inhibitor 1 HPGDS inhibitor 1 is a novel and selective inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS) with IC50 of 0.7 nM.
S8249 HPI-4 (Ciliobrevin A) HPI-4 (Ciliobrevin A, Hedgehog Pathway Inhibitor 4) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo.
S6060 HPK1-IN-2 HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1, a serine/threonine Ste20-related protein kinase), Lck and Flt3 with IC50 of <0.05 μM, IC50 of <0.5 μM and IC50 of <0.05 μM, respectively. HPK1-IN-2 exhibits antitumor activity.
S8970 HQNO HQNO (2-heptyl-4-hydroxyquinoline-N-oxide) is a natural quinolone secreted by P. aeruginosa. HQNO is a potent inhibitor of the electron transport chain with Kd of 64 nM for the ubiquinol-ferricytochrome c oxidoreductase segment (Complex III) of the respiratory chain. HQNO is also an inhibitor of bacterial and mitochondrialType II NADH : quinone oxidoreductase (NDH-2) with IC50 of 7.3 μM in the presence of 50μM menadione.
S8775 HS-1371 HS-1371 is a potent RIP3 kinase inhibitor with an IC50 of 20.8 nM. It binds to the ATP binding pocket of RIP3 and inhibits ATP binding to prevent RIP3 enzymatic activity in vitro.
S9701 HS-243 HS-243 is a highly potent interleukin-1 receptor-associated kinase (IRAK) inhibitor with IC50 of 24 nM, 20 nM and 0.5 μM for IRAK-1, IRAK-4 and TAK1, respectively.
S0408 HS-27 HS-27 is a fluorescently-tethered Hsp90 inhibitor that assays surface Hsp90 expression on intact tissue specimens. HS-27 consists of the core elements of SNX-5422 (Hsp90 inhibitor) and a fluorescein derivative (fluorescein isothiocyanate or FITC) via a PEG linker. HS-27 is potentially used in a see-and-treat paradigm in breast cancer.
A5110 Hsc70 Rabbit Recombinant mAb Hsc70 Rabbit Recombinant mAb detects endogenous levels of total Hsc70.
S0294 HSF1A HSF1A is a cell-permeable heat shock transcription factor 1 (HSF1) activator. HSF1A protects cells from stress-induced apoptosis, binds TRiC subunits and inhibits TRiC activity without perturbation of ATP hydrolysis.
S7097 HSP990 (NVP-HSP990) HSP990 (NVP-HSP990) is a novel, potent and selective HSP90 inhibitor for HSP90α/β with IC50 of 0.6 nM/0.8 nM. NVP-HSP990 induces cell cycle arrest and apoptosis.
A5376 HSPA2 Rabbit Recombinant mAb HSPA2 Rabbit Recombinant mAb detects endogenous level of total HSPA2.
S0014 HT-2157 HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonist of galanin-3 receptor (Gal3).
S5314 HTHQ (1-O-Hexyl-2,3,5-trimethylhydroquinone) HTHQ (1-O-Hexyl-2,3,5-trimethylhydroquinone), which is a hydroquinone monoalkylether, is a potent anti-oxidative and anti-lipid-peroxidative agent. HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone) has considerable anti-oxidative activity by directly reacting with reactive oxygen species (ROS), including peroxyl radicals, and scavenging them to form more stable free radicals.
L5000 HTS Library for Drug Discovery A unique collection of 99040 compounds features numerous structurally diverse compounds and several alternate compositions.
S0079 HUHS015 HUHS015 is a potent, orally active inhibitor of prostate cancer antigen-1 (PCA-1/ALKBH3) with IC50 of 0.67μM.
L4500 Human Endogenous Metabolite Compound Library 1021 small collections of human endogenous metabolites, involving multiple metabolic pathways, which can be used for high-throughput screening, opening up new ways for humans to treat various diseases such as tumors.
L9400 Human Hormone Related Compound Library A unique collection of 478 human hormone related compounds used for high throughput screening(HTS) and high content screening(HCS).
L9600 Human Transcription Factor Compound Library A unique collection of 385 human transcription factor related compounds used for high throughput screening(HTS) and high content screening(HCS).
S5865 Hyaluronic acid Hyaluronic acid (HA, Hyaluronan, Hyaluronate) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is widely used in skin care.
S4424 Hyaluronidase Hyaluronidase (Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase, Amphadase, Hydase, Vitrase) is a naturally occurring enzyme that degrades hyaluronic acid, which constitutes an essential part of the extracellular matrix.
S2562 Hydralazine HCl Hydralazine HCl is a hydrochloride salt of hydralazine, which is a direct-acting smooth muscle relaxant used to treat hypertension by acting as a vasodilator primarily in arteries and arterioles.
S1708 Hydrochlorothiazide Hydrochlorothiazide is a first line diuretic compound of the thiazide class.
S6254 Hydrocinnamic acid Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway phenylalanine metabolism (KEGG). It is an antifungal agent and a metabolite.
S1696 Hydrocortisone (NSC 10483) Hydrocortisone (NSC 10483, Cortisol) is a steroid hormone or glucocorticoid produced by the adrenal gland.
S5501 Hydrocortisone acetate Hydrocortisone Acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.
S6590 Hydrocortisone butyrate Hydrocortisone butyrate is a potent topical corticosteroid that can be used to treat a range of inflammatory skin conditions.
S5972 Hydrocortisone hemisuccinate Hydrocortisone hemisuccinate (A-hydrocort, Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid with anti-inflammatory properties, is an inhibitor of proinflammatory cytokine with IC50 of 6.7 μM and 21.4 μM for Interleukin-6 (IL-6) and IL-3, respectively.
E0177 Hydrocortisone sodium succinate

Hydrocortisone sodium succinate (Hydrocortisone 21-hemisuccinate sodium salt) has significant inhibitory effects on the IL-6 bioactivity with IC50 of 6.7 μM. Hydrocortisone sodium succinate can bind to glucocorticoid receptor, initiating the transcription of anti-inflammatory and immunosuppressive mediators.

S5135 Hydroferulic acid Hydroferulic acid (Dihydroferulic acid, Dihydroconiferylic acid) is classified as a member of the phenylpropanoic acids. It is slightly soluble in water and acidic.
S9206 Hydroprotopine Hydroprotopine (W1171) is a kind of natural herbal extract.
S4658 Hydroquinidine Hydroquinidine (Dihydroquinidine, Hydroconchinine, Hydroconquinine, Dihydroquinine) is an antiarrhythmic agent.
S5114 Hydroquinine Hydroquinine (Dihydroquinine), also known as dihydroquinine, is an organic compound and as a cinchona alkaloid closely related to quinine.
S4580 Hydroquinone Hydroquinone (Quinol, 1,4-Benzenediol, 1,4-Dihydroxybenzene, HQ) is a Melanin Synthesis Inhibitor. The physiologic effect of hydroquinone is by means of Depigmenting Activity. It also posesses antioxidant properties that can cause toxicity in several organs, notably the kidney.
S3947 Hydroumbellic acid Hydroumbellic acid (2,4-Dihydroxyhydrocinnamic acid) is used as pharmaceutical intermediates.
S3898 Hydroxy Camptothecine Hydroxy Camptothecine (10-Hydroxycamptothecin, Hydroxycamptothecine) is a cell-permeable powerful DNA topoisomerase I inhibitor. It has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones.
S1798 Hydroxy-PEG1-CH2-Boc Hydroxy-PEG1-CH2-Boc is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
S0595 Hydroxy-PEG2-(CH2)2-Boc Hydroxy-PEG2-(CH2)2-Boc is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S1871 Hydroxy-PEG2-CH2-Boc Hydroxy-PEG2-CH2-Boc is a PEG/Alkyl/ether-based PROTAC linker that is applicable to the synthesis of PROTACs.
S1728 Hydroxy-PEG2-CH2COOH Hydroxy-PEG2-CH2COOH is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
S0583 Hydroxy-PEG3-(CH2)2-Boc Hydroxy-PEG2-(CH2)2-Boc is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S1745 Hydroxy-PEG3-CH2-Boc Hydroxy-PEG3-CH2-Boc is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
S0578 Hydroxy-PEG4-(CH2)2-Boc Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S1846 Hydroxy-PEG4-O-Boc Hydroxy-PEG4-O-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
S1495 Hydroxy-PEG5-Boc Hydroxy-PEG5-Boc is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
S1797 Hydroxy-PEG6-CH2-Boc Hydroxy-PEG6-CH2-Boc is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
S4430 Hydroxychloroquine Sulfate (NSC 4375) Hydroxychloroquine Sulfate (NSC 4375, HCQ) is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.
S9205 Hydroxygenkwanin Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, has anti-oxidant ability and can act as tissue factor (TF) inhibitor to prevent thrombosis.
S5547 Hydroxylammonium chloride Hydroxylammonium chloride (Hydroxylamine hydrochloride) is the hydrochloric acid salt of hydroxylamine, which is a biological intermediate in the nitrification and in the anammox.
S4674 Hydroxyprogesterone caproate Hydroxyprogesterone Caproate (17α-Hydroxyprogesterone hexanoate, 17α-Hydroxyprogesterone caproate) is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium.
S4115 Hydroxypropyl Cellulose Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility, it is used as food additive and sieving matrix for DNA separations.
S3826 Hydroxytyrosol Hydroxytyrosol (3,4-dihydroxyphenylethanol) is one of the main phenolic components of olive oil with excellent antioxidant, antimicrobial and anticarcinogenic activities.
S1896 Hydroxyurea (NSC-32065) Hydroxyurea (NSC-32065, NCI-C04831, Hydroxycarbamide) is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase. Hydroxyurea activates apoptosis and autophagy. Hydroxyurea is used to treat HIV infection.
S4026 Hydroxyzine 2HCl Hydroxyzine is a histamine H1-receptor antagonist, inhibits binding of [3H]pyrilamine/[3H]desloratadine to human histamine H1 receptor with IC50 of 10 nM/19 nM.
S5649 Hydroxyzine pamoate Hydroxyzine Pamoate is the pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.
S2908 Hygromycin B Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.
S2311 Hyodeoxycholic acid (HDCA) Hyodeoxycholic (HDCA, NSC 60672) acid is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria.
S4014 Hyoscyamine Hyoscyamine (Daturine) is an AChR inhibitor with IC50 of 7.5 nM.
E0201 Hypaconitine Hypaconitine (Deoxymesaconitine) is an active diterpene alkaloid derived from Aconitum species. Hypaconitine inhibits TGF-β1-induced epithelial–mesenchymal transition.
S0911 Hypaphorine Hypaphorine which is abundantly found in vaccaria semen, counteracts inflammation via inhibition of ERK or/and NFκB signaling pathways.
S3273 Hypericin Hypericin (Hyp, HY) is a naturally occurring substance found in the common St. John's Wort (Hypericum species) with antidepressive, antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities. Hypericin has inhibitory effects on MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450).
S5453 Hyperoside Hyperoside (Hyperin, Quercetin 3-galactoside), a naturally occuring flavonoid compound, exerts multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.Hyperoside can inhibit activation of the NF-κB signaling pathway.
E0010 Hypocrellin A Hypocrellin A (HA) is a perylenequinone isolated from Shiraia bambusicola that shows antiviral, antimicrobial and anticancer activity through mediating multiple signaling pathways. Hypocrellin A also is a selective and potent inhibitor of PKC.
S2424 Hypoxanthine Hypoxanthine, a naturally occurring purine derivative, an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine.
S4444 Hypromellose Hypromellose (Hydroxypropyl Methyl Cellulose, HPMC, Celacol HPM 5000) is a commonly employed cellulose ether used in the fabrication of hydrophilic matrices. Hypromellose provides the release of a drug in a controlled manner, effectively increasing the duration of release of a drug to prolong its therapeutic effect.
S0203 HZ-1157 HZ-1157 is an inhibitor of hepatitis C virus (HCV) with inhibitory activities toward HCV NS3/4A protease.
S3914 α-Hederin α-hederin is a water-soluble pentacyclic triterpenoid saponin which has shown hemolytic and apoptotic properties.