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Catalog No. Product Name Information
S2251 (-)-Huperzine A (HupA) (-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4.
S4760 (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD, HP-β-cyclodextrin, Hydroxypropyl betadex, Hydroxypropyl-β-cyclodextrin) is a well-known sugar used in drug delivery, genetic vectors, environmental protection, and the treatment of Niemann-Pick disease type C1 (NPC1). It is an inhibitor of amyloid-β aggregation and widely used drug delivery vehicle to improve stability and bioavailability.
S5902 1,2,3,4,5,6-Hexabromocyclohexane 1,2,3,4,5,6-Hexabromocyclohexane (NSC7908) is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation with IC50 value to be estimated in low micromolar range.
S4173 1-Hexadecanol 1-Hexadecanol is a fatty alcohol used to make other chemicals.
S6364 1-Hydroxy-2-naphthoic acid 1-Hydroxy-2-naphthoic acid is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms.
S3089 12-Hydroxydodecanoic acid

12-Hydroxydodecanoic acid (G12) is an active endogenous metabolite.
S4507 17-Hydroxyprogesterone 17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.
S5853 2'-Hydroxy-2-methoxychalcone 2'-Hydroxy-2-methoxychalcone is a chemical.
S5173 2'-Hydroxy-4'-methylacetophenone 2'-Hydroxy-4'-methylacetophenone may be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl)oxy]acetophenone and possesses acaricidal property.
S9375 2'-Hydroxyacetophenone 2'-Hydroxyacetophenone is a flavouring ingredient.
S6198 2-Hexanone 2-Hexanone, a volatile organic compound, is used as a general solvent.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S6183 2-Hydroxy-2-methylbutanoic acid 2-Hydroxy-2-methylbutyric acid is an unusual metabolite found in the urine of patients with 2-hydroxyglutaric aciduria and maple syrup urine disease. 2-Hydroxy-2-methylbutyric acid is also a secondary metabolite found in human urine after exposure to the gasoline additive tert-amyl-Me-ether (TAME).
S6098 2-Hydroxy-3-methylbutanoic acid 2-Hydroxy-3-methylbutanoic acid (3-Methyl-2-hydroxybutyric acid, 2-Hydroxyisopentanoic acid, 2-Oxyisovaleric acid) is a metabolite found in the urine of patients with phenylketonuria, methylmalonic acidemia, propionic acidemia, 3-ketothiolase deficiency, isovaleric acidemia, 3-methylcrotonylglycemia, 3-hydroxy-3-methylglutaric acidemia, multiple carboxylase deficiency, glutaric aciduria, ornithine transcarbamylase deficiency, glyceroluria, tyrosinemia type I, galactosemia, and maple syrup urine disease.
S5562 2-Hydroxybenzyl alcohol 2-Hydroxybenzyl alcohol (Salicyl alcohol, Salicain, Diathesin, Saligenin, Saligenol, o-Methylolphenol, α,2-Toluenediol), which can be found in a number of food items such as red huckleberry, rye, jerusalem artichoke, and ceylon cinnamon, is precursor of salicylic acid and is formed from salicin by enzymatic hydrolysis by Salicyl-alcohol beta-D-glucosyltransferase or by acid hydrolysis.
E0025 2-Hydroxybenzylamine 2-Hydroxybenzylamine (2-(Aminomethyl)phenol, 2-HOBA, NSC 127870) is a naturally occurring compound found in buckwheat and is a selective scavenger of dicarbonyl electrophiles that protects proteins and lipids from being modified by these electrophiles. 2-HOBA reduces inflammation and plaque apoptotic cells and promotes efferocytosis and features of stable plaques. 2-HOBA has potential for use as a nutrition supplement due to its ability to protect against the damaging effects of oxidative stress.
S6119 2-Hydroxybutyric acid 2-Hydroxybutyric acid (α-hydroxybutyrate) is converted from 2-Aminobutyric acid. It is produced in mammalian tissues (principally hepatic) that catabolize L-threonine or synthesize glutathione.
S3323 2-Hydroxycaproic acid

2-Hydroxyhexanoic acid (2-Hydroxyhexanoic acid) is an endogenous metabolite.
S5436 2-Hydroxycaprylic acid 2-Hydroxycaprylic acid (2-hydroxyoctanoic acid) belongs to the class of organic compounds known as medium-chain fatty acids.
E0652 2-Hydroxyisocaproic acid 2-hydroxyisocaproic acid (HICA), an amino acid derivative, has broad antibacterial activity.
S6360 2-Hydroxypyridine 2-Hydroxypyridine (2-Pyridino, 2-Pyridone) is used in peptide synthesis.
S2417 20-Hydroxyecdysone 20-Hydroxyecdysone (Ecdysterone, 20E, B-ecdysone, Commisterone, Crustecdysone) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods.20-Hydroxyecdysone (Ecdysterone, 20E) inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP.
S9009 23-Hydroxybetulinic acid 23-Hydroxybetulinic acid is a natural lupanetype pentacyclic triterpene isolated from the root of traditional Chinese herb Pulsatilla chinensis with remarkable antineoplastic activities.
S8091 25-Hydroxycholesterol 25-Hydroxycholesterol is a side-chain oxysterol and a selective suppressor of IgA production by B cells with an EC50≈65 nM. It affects the immune system and has a key role in the pathogenesis of atherosclerosis.
S3260 3'-hydroxy Puerarin 3'-hydroxy Puerarin is an isoflavone isolated from Puerariae Lobatae Radix.
S3210 3'-Hydroxy-4'-methoxyacetophenone 3'-Hydroxy-4'-methoxyacetophenone (Acetoisovanillone, Isoacetovanillone, Diosmin EP Impurity A) is an active P. spinosa extract with anti-inflammatory potential.
S3940 3'-Hydroxypterostilbene 3'-Hydroxypterostilbene (3'-HPT) is one of the active constituents of Sphaerophysa salsula and Pterocarpus marsupium which may be useful in treating different types of haematological malignancies. 3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways.
S3339 3-(2-Hydroxyphenyl)propionic acid

3-(2-Hydroxyphenyl)propanoic acid (Melilotic acid, Melilotate, 2-hydroxybenzenepropanoic acid) is an endogenous metabolite.
S6074 3-(3-Hydroxyphenyl)propionic Acid 3-(3-Hydroxyphenyl)propionic acid (m-Hydroxyphenylpropionic acid, 3-Hydroxyhydrocinnamic acid) is one of the major metabolites of ingested caffeic acid and of the phenolic degradation products of proanthocyanidins by the microflora in the colon.
S5835 3-(4-Hydroxyphenyl)-1-propanol 3-(4-Hydroxyphenyl)-1-propanol is a reagent in the synthesis of (−)-Centrolobine, which is an anti-Leishmania agent.
S3157 3-Hydroxybenzaldehyde

3-Hydroxybenzaldehyde (3-HBA), one of the benzaldehydes commonly found in nature, is produced by 3-hydroxybenzyl-alcohol dehydrogenase, and is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans (ALDH2). 3-Hydroxybenzaldehyde exhibits vasculoprotective effects.
S6367 3-Hydroxybenzoic acid 3-Hydroxybenzoic acid (m-Hydroxybenzoic acid, 3-Carboxyphenol, m-Salicylic acid) is used as an intermediate in the synthesis of plasticisers, resins, pharmaceuticals, etc.
S6363 3-Hydroxybenzyl alcohol 3-Hydroxybenzyl alcohol is used as an intermediate to produce other chemicals.
S1031 3-Hydroxybutyric acid (BHB) 3-Hydroxybutyric acid (BHB) is a small molecule metabolite that is elevated in type I diabetes.,
S5586 3-Hydroxycinnamic acid 3-hydroxycinnamic acid (meta-Coumaric acid, m-Coumaric acid, m-Coumarate) is an aromatic acid that can be found in vinegar.
S4790 3-Hydroxyflavone 3-Hydroxyflavone (Flavon-3-ol, 3-HF, 3-Hydroxy-2-phenylchromone) is the simplest molecule of the flavonol class that is usually used in synthesis of biologically active molecules.
S6124 3-Hydroxyisovaleric acid 3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine.
S6252 3-Hydroxypicolinic acid 3-Hydroxy picolinic acid is a picolinic acid derivative and is a member of the pyridine family. It is used as a matrix for nucleotides in MALDI mass spectrometry analyses
S4937 4'-Hydroxychalcone 4'-Hydroxychalcone (P-Cinnamoylphenol), found in herbs and spices and tea, is a member of the class of compounds known as retrochalcones. It has diverse biological activities, inhibiting TNFα-induced NF-κB pathway activation in a dose-dependent manner and activating BMP signaling.
S5396 4'-Hydroxypropiophenone 4'-Hydroxypropiophenone (Paroxypropione, p-hydroxypropiophenone) is a member of acetophenones.
S9793 4-HNE (4-Hydroxynonenal) 4-HNE (4-Hydroxynonenal) is one of the major end products of lipid peroxidation and has been widely accepted as an inducer of oxidative stress.
S5178 4-Hydroxy-2,5-dimethyl-3(2H)furanone 4-Hydroxy-2,5-dimethyl-3(2H)furanone (furaneol, HDMF) is a naturally occurring substance found in a variety of fruits and has been shown to have antimicrobial activity.
S4942 4-Hydroxy-3,5-dimethoxybenzyl alcohol 4-Hydroxy-3,5-dimethoxybenzyl alcohol (Syringic alcohol, Syringyl alcohol) is a kind of phenol with antiviral properties.
S6297 4-Hydroxy-3-methylbenzoic acid 4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a healthy population.
S3754 4-Hydroxybenzoic acid 4-Hydroxybenzoic acid (p-hydroxybenzoic acid, PHBA, para-Hydroxybenzoic acid, 4-hydroxybenzoate), also known as p-hydroxybenzoic acid (PHBA), is a phenolic derivative of benzoic acid and widely used in organic synthesis. It is the most widely distributed aromatic organic acid in the vegetable kingdom.
S3857 4-Hydroxybenzyl alcohol 4-hydroxybenzyl alcohol (P-Methylolphenol, 4-Methylolphenol), an important phenolic constituent of Gastrodia elata Blume (GEB), has been shown to have many beneficial effects in different animal models of neurological disorders, such as, headaches, convulsive behavior, dizziness, and vertigo.
S4763 4-Hydroxychalcone 4-Hydroxychalcone (P-Cinnamoylphenol) is a chalcone metabolite with diverse biological activities. It inhibits TNFα-induced NF-κB pathway activation in a dose-dependent manner and also activates BMP signaling.
E2226 4-Hydroxyderricin 4-Hydroxyderricin(4-HD), the major active ingredients of Angelica keiskei Koidzumi, is a potent selective monoamine oxidase (MAO) inhibitor with mild inhibitory effect on dopamine β-hydroxylase.
S2995 4-Hydroxyphenylpyruvic acid 4-Hydroxyphenylpyruvic acid (4-HPPA), an abundant colon metabolite of polyphenols, is a potent scavenger that suppresses levels of free radicals and cyclooxygenase-2 (COX-2) and contributes to reduced risk of colon cancer development.
S9360 4-Hydroxyquinazoline 4-Hydroxyquinazoline (Quinazolin-4-ol, 4-Quinazolinol) is a PARP inhibitor with a high potency for PARP-1 with IC50 of 9.5 μM.
S7827 4-Hydroxytamoxifen (Afimoxifene) 4-Hydroxytamoxifen (Afimoxifene) is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. It activates on-target modification frequency for intein-Cas9 variants.
S3316 5-Hydroxy-1-tetralone

5-hydroxy-1-tetralone is a fluorescent labeling reagent for the determination of glycosphingolipid from small amounts of biological samples.
S6081 5-Hydroxymethyl-2-furancarboxylic acid 5-Hydroxymethyl-2-furancarboxylic acid is the main metabolite of 5-hydroxymethyl-2-furfural, a product of acid-catalyzed degradation of sugars during the heating and storage of foods that influences taste and physiological functions in the body.
E0027 5-Hydroxymethylcytosine 5-Hydroxymethylcytosine (5hmC) is a naturally existing component in mammalian genomic DNA and is regarded as the sixth DNA base. 5-Hydroxymethylcytosine is an intermediate metabolite in active DNA demethylation. 5-Hydroxymethylcytosine is epigenetic marks known to affect global gene expression in mammals.
S3772 5-Hydroxymethylfurfural 5-Hydroxymethylfurfural (5-HMF) is an important bio-sourced intermediate, formed from carbohydrates such as glucose or fructose and used for production of fuels and chemical intermediates.
S6127 5-Hydroxymethyluracil 5-Hydroxymethyluracil (5hmU) is a thymine base modification found in the genomic DNA of diverse organisms ranging from bacteriophages to mammals
S2374 5-hydroxytryptophan (5-HTP) 5-Hydroxytryptophan (5-HTP, NSC-92523), also known as oxitriptan (INN), is a naturally occurring amino acid and chemical precursor for the treatment of depression.
S9330 6-Hydroxy-4-methylcoumarin 6-Hydroxy-4-methylcoumarin is a chemical.
S3315 6-Hydroxyindole

6-Hydroxyindole (1H-indol-6-ol) is an endogenous potent and long-lasting OATP1B1 inhibitor with IC50 of ~10 μM.
S6285 6-Hydroxynicotinic acid 6-Hydroxynicotinic acid is widely used in the manufacture of industrial products.
S7330 6H05 6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C).
S4767 7-Hydroxy-3,4-dihydrocarbostyril 7-Hydroxy-3,4-dihydrocarbostyril is used as the materials for the organic synthesis intermediates.
S5548 7-Hydroxy-4-chromone 7-Hydroxychromone is an inhibitor of Src kinase with IC50 of <300 μM.
S9331 7-Hydroxy-4-methyl-8-nitrocoumarin 7-Hydroxy-4-methyl-8-nitrocoumarin is a chemical.
S3936 7-Hydroxycarbostyril 7-Hydroxycarbostyril (3,4-Dihydro-7-hydroxycarbostyril) is a kind of pharmaceutical intermediate.
S3920 7β-Hydroxylathyrol 7β-Hydroxylathyrol (7beta-Hydroxylathyrol, 7-Hydroxylathyrol) is natural occuring product extracted from the seeds of Euphorbia lathyris L.
S4547 8-Hydroxyquinoline 8-Hydroxyquinoline (8-Oxychinolin, 8-Quinolinol, Oxine) is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes.
S1582 H 89 2HCl H 89 2HCl is a potent PKA inhibitor with Ki of 48 nM in a cell-free assay, 10-fold selective for PKA than PKG,500-fold greater selectivity than PKC, MLCK, calmodulin kinase II and casein kinase I/II. H 89 2HCl induces autophagy.
S6214 H-1152 dihydrochloride H-1152 dihydrochloride (2HCl) is a membrane-permeable and selective inhibitor of Rho-associated protein kinase (ROCK). H-1152 inhibits ROCK2, PKA, PKC, PKG, AuroraA and CaMK2 with IC50 of 0.0120 μM, 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
S6652 H-151 H-151 is a highly potent and covalent antagonist of STING that has noteworthy inhibitory activity both in human cells and in vivo.
S6203 H-Abu-OH H-Abu-OH (2-Aminobutyric acid, 2-Aminobutanoic acid, Homoalanine, α-Aminobutanoic acid, Ethylglycine) is a non-proteinogenic alpha amino acid that is used by nonribosomal peptide synthases.
S5522 H-Cys(Trt)-OH H-Cys(Trt)-OH (L-Cys(Trt)-OH, H-L-Cys(Trt)-OH, S-Tritylcysteine,S-Trityl-L-cysteine) is a specific inhibitor of Eg5 that inhibits Eg5-driven microtubule sliding velocity in a reversible fashion with an IC50 of 500 nM.
S6253 H-D-Trp-OH H-D-Trp-OH (D-Tryptophan) is the D-enantiomer of tryptophan, which is an essential amino acid in the human diet.
S6133 H-Gly-Pro-OH H-Gly-Pro-OH (Glycyl proline, Glycyl-L-proline) is a dipeptide composed of glycine and proline, and is an end product of collagen metabolism that is further cleaved by prolidase. The resulting proline molecules are recycled into collagen or other proteins.
S6109 H-HoArg-OH H-HoArg-OH (L-Homoarginine) is an organ-specific, uncompetitive inhibitor of serum "bone and liver" alkaline phosphatase.
E2634 H-Leu-Leu-OMe Hydrochloride H-Leu-Leu-OMe Hydrochloride (H-LEU-LEU-OME HCL, L-Leucyl-L-Leucine methyl ester), a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential, also can induce endolysosomal pathway stress.
S6093 H-Phe-Phe-OH H-Phe-Phe-OH (Phenylalanyl-phenylalanine, Phe-Phe, L-Phe-L-Phe) is a short peptide diphenylalanine with utility for potential applications in biomaterial chemistry, sensors and bioelectronics.
S6044 H-Tyr(3-I)-OH H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) is responsible for catalyzing the first step of the noradrenergic biosynthesis pathway. H-Tyr(3-I)-OH is an effective tyrosine hydroxylase inhibitor.
S9687 H2DCFDA (DCFH-DA) H2DCFDA (DCFH-DA) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) production. It is de-esterified intracellularly and turns to highly fluorescent 2′,7′-dichlorofluorescein upon oxidation. It is used in sensitive and rapid quantitation of oxygen-reactive species in response to oxidative metabolism; microplate assay for detecting oxidative products in phagocytic cells, and quantitative multiwell myeloid differentiation assay.(Ex/Em=488/525 nm)
S3244 H3B-120 H3B-120 is a competitive, selective and allosteric inhibitor of carbamoyl phosphate synthetase 1 (CPS1) with IC50 of 1.5 μM and Ki of 1.4 μM. H3B-120 exhibits anti-tumor activity.
S8746 H3B-5942 H3B-5942 is a selective and irreversible estrogen receptor covalent antagonist, inactivates both ERα WT and ERα mutation. The Ki values are 1 nM and 0.41 nM, respectively.
S8675 H3B-6527 H3B-6527 is a highly selective covalent FGFR4 inhibitor with an IC50 value of <1.2 nM and at least 250-fold selectivity over FGFR1-3 (IC50 values of 320, 1,290 and 1,060 nM respectively).
S9716 H3B-8800 H3B-8800 is a potent and orally active modulator of SF3B splicing. H3B-8800 interacts directly with the SF3b complex, demonstrating anti-cancer properties. H3B-8800 holds promise for studying acute myeloid leukemia (AML) with SF3B1 mutations.
E2646 HA-100 HA-100 is an inhibitor of cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase.
S2964 HA-100 dihydrochloride HA-100 dihydrochloride is an inhibitor of cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase with IC50 of 4 μM, 8 μM, 12 μM and 240 μM, respectively.
S0424 HA130 HA130 is a selective autotaxin (ATX) inhibitor with IC50 of 28 nM.
S1071 HA14-1 HA14-1 is a non-peptidic ligand of a Bcl-2 surface pocket with IC50 of ~9 μM.
S8299 HA15 HA15 is a molecule that targets specifically HSPA5 (Heat shock 70kDa protein 5) also known as BiP (Immunoglobulin heavy-chain-binding protein) or Grp78 (glucose-regulated protein 78). HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
E3247 Hainan Nightshade Fruit Extract Hainan Nightshade Fruit Extract is extracted from the fruit of Hainan Nightshade, which has immunity-boosting powers and pain-eliminating abilities since it reduces inflammation and swelling in the body.
S6440 Halazone Halazone (Pantocide, p-sulfondichloramidobenzoic acid) is widely used to disinfect drinking water.
S4098 Halcinonide Halcinonide(SQ-18566) is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.
E3642 Haliotidis concha Extract Haliotidis Concha Extract is extracted from the shell of Haliotidis Concha, which influences calcium channels, expression of PMCA1 mRNA, and regulates ion calcium channels and calcium-ATPase.
S4089 Halobetasol Propionate Halobetasol Propionate (BMY-30056, CGP-14458,Ulobetasol propionate) is an anti-inflammatory and a dermatologic agent commonly used to treat psoriasis.
S8144 Halofuginone Halofuginone (RU-19110) is the competitively inhibitor of prolyl-tRNA synthetase with Ki of 18.3 nM.It could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in mammal.
S1920 Haloperidol Haloperidol (Haldol) is an antipsychotic and butyrophenone.
S9469 Haloperidol Decanoate Haloperidol decanoate (Halomonth) is a depot form of haloperidol with antipsychotic activity. It has potential to be used in the research of schizophrenia and schizoaffective disorder.
S4570 Halothane Halothane (Narcotane) is a general inhalation anesthetic used for induction and maintenance of general anesthesia.
S0148 HAMNO HAMNO (NSC-111847) is a potent and selective replication protein A (RPA) inhibitor with anti-tumor activity. HAMNO inhibits both ATR autophosphorylation and phosphorylation of RPA32 Ser33 by ATR.
E0009 Harmane Harmane (Harman, Aribine, Aribin, Locuturine, Locuturin, Loturine, Passiflorin, 1-Methylnorharman, NSC 54439) is a common compound in several foods, plants and beverages. Harmane is a selective monoamine oxidase inhibitors with IC50s of 0.5 μM and 5 μM for human MAO A and MAO B, respectively. Harmane also inhibits the apurinic/apyrimidinic (AP) endonuclease activity of the UV endonuclease induced by phage T4.
S3868 Harmine Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.
S3817 Harmine hydrochloride Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.
S9171 Harpagoside Harpagoside, a natural product found in the plant Harpagophytum procumbens, has potent anti-rheumatic, anti-inflammatory and analgesic effects.
S9063 Harringtonine Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.
E3341 Hawthorn Extract Hawthorn Extract is extracted from Crataegus, which has pharmacological activities such as hypotensive, antihyperlipidemic, antihyperglycemic, anxiolytic, immunomodulatory, and antimutagenic.
E0078 HBC 530 HBC 530 is an RNA mimic of GFP fluorophore for imaging in live cells and activated by binding to Pepper aptamers.
E0623 HBC620 HBC620 is an analogue of HBC which is a GFP fluorophore-like synthetic dye that is nonfluorescent in solution, but strongly fluoresces upon forming tight complex with Pepper RNA aptamer. HBC-Pepper complex can be used to visualize RNA dynamics in live cells.
S6883 HBX 19818 HBX19818 is a specific inhibitor of USP7 with an IC 50 of 28.1 μM.
S2918 HC-030031 HC-030031 (TOSLAB 829227) is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively.
S6637 HC-067047 HC-067047 is a selective TRPV4 channel antagonist with IC50 values of 48 nM,133 nM,and 17 nM for human, rat, and mouse TRPV4 orthologs,respectively.
S0547 HCH6-1 HCH6-1 is a selective competitive antagonist of formyl peptide receptor 1 (FPR1) and has protective effects against acute lung injury (ALI). HCH6-1 may have potential as a new therapeutic agent for treating FPR1-involved inflammatory lung diseases.
E2834 Hck-IN-1 Hck-IN-1, a selective Nef-dependent Hck inhibitor, blocks the kinase activity of the Nef:Hck complex in vitro with an IC50 value of 2.8 μM, whereas its activity against Hck alone is >20 μM, also blocks wild-type HIV-1 replication with an IC50 value in the 100-300 nM range.
S0746 hDHODH-IN-1 hDHODH-IN-1 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with anti-inflammatory effect.
E1216 Heclin Heclin is an inhibitor of HECT-type E3 ubiquitin ligase with an IC50 of 6.8, 6.3, and 6.9 μM for Smurf2, Nedd4, and WWP1 HECT domains, respectively.
S5336 Hecogenin Hecogenin (Hocogenin), a steroid saponin isolated from Agave sisalana, is a potent and highly selective inhibitor of UGT1A4 with an IC50 value of 1.5 μM.
E3084 Hedera Helix Extract Hedera Helix Extract is extracted from Hedera Helix, which is safe for use in cough due to acute URTIs and bronchitis.
S3919 Hederacoside C Hederacoside C (HDC, Kalopanaxsaponin B) is one of the active ingredients in Hedera helix leaf extract (Ivy Ex.) and used to treat respiratory disorders.
S9011 Hederacoside D Hederacoside D is one of the major bioactive saponins and plays pivotal roles in the overall biological activity.
S3899 Hederagenin Hederagenin (Caulosapogenin, Hederagenol, Hederagenic acid, Astrantiagenin E) is a highly water insoluble triterpenoid compound that can be found in various plants including Hedera helix and Chenopodium quinoa. It exhibits a variety of biological activities, including potent antitumor properties both in vitro and in vivo. Hederagenin inhibits LPS-stimulated expression of iNOS, COX-2, and NF-κB.
E3020 Hedyotic Diffusa Extract Hedyotic Diffusa Extract is extracted from Hedyotic diffusa, of which polysaccharides inhibit the growth of CNE2 cells in a dose-and-time-dependent way, the mechanism may involve induction of cell apoptosis, which is associated with the activation of Bax and caspase-3 protein and the down-regulation of Bcl-2 protein expression.
S4965 Helecin Helecin (Helicin) is the O-glucoside of salicylaldehyde, which is a key precursor to a variety chelating agents.
S3797 Helicide Helicide (4-formylphenyl-O-β-d-allopyranoside), a main active constituent from seeds of the Chinese herb Helicia nilagirica, has been reported to exert a sedative, analgesic and hypnotic effect, and is used clinically to treat neurasthenic syndrome, vascular headaches and trigeminal neuralgia.
E2826 Hematein Hematein inhibits casein kinase II activity in a selective, dose-dependent and ATP non-competitive manner in vitro, with IC50 of 0.55 μM in the presence of 10 μM ATP.
S2384 Hematoxylin Hematoxylin (Hydroxybrazilin) is a compound that forms strongly colored complexes with certain metal ions, notably Fe(III) and Al(III) salts and a kind of stain in histology.
S5645 Hemin Hemin (protohemin) is an iron-containing porphyrin used in the management of porphyria attacks, particularly in acute intermittent porphyria.Hemin is an Heme oxygenase (HO)-1 inducer.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
S5992 Heparan Sulfate Heparan sulfate (HS, Heparitin sulfate, Alpha-idosane, HHS 5, N-Acetylheparan Sulfate, Suleparoid, Tavidan), a constituent of HS proteoglycans (HSPGs), is a linear polysaccharide present on the cell surface. Heparan sulfate influences the binding affinity of intestinal epithelium cells (IECs) to Wnt, thereby promoting activation of canonical Wnt signaling and facilitating regeneration of small intestinal crypts after epithelial injury.
S1346 Heparin sodium Heparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins. Heparin is used as an anticoagulant primarily through its interaction with AT III by enhancing AT-IIImediated inhibition of blood coagulation factors, including thrombin and factor Xa. Heparin prevents the induction of autophagy.
S6831 HEPES HEPES is a nonvolatile zwitterionic chemical buffering agent, which is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis.
E0380 Hepln-13 Hepln-13 is a potent and orally active Hepsin inhibitor with an IC50 of 0.33 µM, can be used for the research of metastatic prostate cancer.
S3336 Heptadecanoic acid

Heptadecanoic acid (C17:0), an odd chain saturated fatty acid, significantly inhibits cell proliferation, and migration, while promoting apoptosis in PC‑9 and PC‑9/GR cells. Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis.
S1697 Heptaethylene glycol Heptaethylene glycol (HO-PEG7-OH) is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
S3389 Heptamidine Dimethanesulfonate Heptamidine (SBi4211) Dimethanesulfonate is a novel and potent Pentamidine-related inhibitor of the calcium-binding protein S100B with a Kd of 6.9 μM.
E3324 Herba Abri Extract Herba Abri Extract is extracted from Herba Abri, which is used to treat acute or chronic hepatitis and mastitis.
E3825 Herba Artemisiae Capillaris Extract Herba Artemisiae Capillaris Extract is extracted from Herba artemisiae capillaris, which prevents diabetic nephropathy.
E3741 Herba Siegesbeckiae Extract Herba Siegesbeckiae Extract is obtained from Herba Siegesbeckiae, which is regarded as a promising medical plant with various chemical compounds and numerous pharmacological activities.
E3597 Herba taxilli Extract Herba Taxilli Extract is extracted from Taxillus sutchuenensis, which can be used as inhibitors of HCV NS3 serine protease.
E0208 Herbacetin

Herbacetin is a natural flavonoid compound found in flaxseed with strong antioxidant, antitumor and anti-inflammatory activity.
E3292 Hericium Erinaceus Extract Hericium Erinaceus Extract is extracted from Hericium Erinaceus, which can be used in treatment for depressive disorders.
S1529 Hesperadin Hesperadin potently inhibits Aurora B with IC50 of 250 nM in a cell-free assay. It markedly reduces the activity of AMPK, Lck, MKK1, MAPKAP-K1, CHK1 and PHK while it does not inhibit MKK1 activity in vivo.
S2308 Hesperetin Hesperetin is a bioflavonoid and, to be more specific, a flavanone.
S2309 Hesperidin Hesperidin (Cirantin) is a flavanone glycoside found abundantly in citrus fruits.
S6426 Hesperidin methylchalcone Hesperidin methylchalcone is the Citrus original products with powerful antioxidant activity.
S0969 Heterophyllin B Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla, which provides a novel strategy for the treatment of esophageal cancer.
E0029 Hexa-D-arginine

Hexa-D-arginine is a potent and specific furin inhibitor with Ki values of 106 nM, 580 nM, and 13.2 μm for furin, PACE4, and PC1, respectively.
S4632 Hexachlorophene Hexachlorophene (Hexachlorofen, Fostril, Nabac, pHisoHex) is a potent KCNQ1/KCNE1 potassium channel activator with EC50 of 4.61 ± 1.29 μM; It can also attenuate Wnt/beta-catenin signaling through the Siah-1-mediated beta-catenin degradation.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S6147 Hexadecanedioic acid Hexadecanedioic acid (Thapsic acid, Hexadecanedioate, Palmitic acid) is a common saturated fatty acid found in animals, plants and microorganisms. It has antitumor activity.
E2274 Hexahydrocurcumin Hexahydrocurcumin is one of the major metabolites of curcumin and a selective, orally active COX-2 inhibitor, which has antioxidant, anticancer and anti-inflammatory activities.
S4069 Hexamethonium Dibromide Hexamethonium Dibromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia.
E0160 Hexaminolevulinate hydrochloride

Hexaminolevulinate hydrochloride (5-Aminolevulinic acid hexyl ester hydrochloride) is a tumour photosensitizer.
S2473 Hexestrol Hexestrol (Bibenzyl) binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.
S6408 Hexetidine Hexetidine is an anti-bacterial and anti-fungal agent with local anesthetic, astringent, deodorant and antiplaque activity.
S3588 Hexylene glycol Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics. Hexylene glycol exhibits antibacterial and antifungal properties.
S4571 Hexylresorcinol Hexylresorcinol (4-Hexylresorcinol) is an organic compound with local anaesthetic, antiseptic and anthelmintic properties, is a potent inhibitor of mushroom tyrosinase. The IC50 values of hexylresorcinol for monophenolase is 1.24 μM and for diphenolase is 0.85 μM.
E4464 Hexythiazox Hexythiazox is a selective acaricide with ovicidal, larvicidal and nymphicidal activities. It is widely used for chemical control of mites on cotton, fruits and vegetables.
S2948 HG-10-102-01 HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2 with IC50 of 23.3 nM and the G2019S mutant with IC50 of 3.2 nM.
S6513 HG-14-10-04 HG-14-10-04 is an inhibitor of ALK.
S8393 HG-9-91-01 HG-9-91-01 (SIK inhibitor 1) is a potent and highly selective inhibitor of salt-inducible kinase (SIK) with IC50 of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3, respectively.
E1080 HG106 HG106, a potent SLC7A11 inhibitor, leads to enhanced ROS generation, ER stress, and ultimately growth arrest specifically in KRAS-mutant lung adenocarcinoma (LUAD).
E1748 HG6-64-1 HG6-64-1 (HMSL 10017-101-1) is a highly potent and selective inhibitor of B-Raf with an IC50 of 0.09 μM on B-raf V600E transformed Ba/F3 cells.
S6882 HI-TOPK-032 HI-TOPK-032 is a potent and specific inhibitor of TOPK. HI-TOPK-032 also reduces ERK-RSK phosphorylation, regulates of the abundance of p53, cleaved caspase-7, and cleaved PARP, and induces apoptosis in cancer cells.
S0950 Hibifolin Hibifolin (Gossypetin-8-O-β-D-glucuronide) is a flavonol glycoside and acts as a potential inhibitor of adenosine deaminase (ADA) with a Ki of 49.92 μM. Hibifolin prevents β-amyloid-induced neurotoxicity in cultured cortical neurons.
E3506 Hibiscus bark Extract Hibiscus Bark Extract is extracted from the bark of Hibiscus, which has antidepressant-like and neuroprotective effects.
E3203 Hibiscus Flower Extract Hibiscus flower extract is extracted from the flower of Hibiscus mutabilis, which has many medicinal and anticancer properties due to its antioxidant and hypolipidemic effects.
E3445 Hibiscus sabdariffa flower Extract Hibiscus sabdariffa flower Extract is extracted from the flowers of Hibiscus sabdariffa, which enhances anti-inflammatory effects by increasing expression of anti-inflammatory cytokines and decreasing pro-inflammatory cytokines.
E3505 Hibiscus syriacus flower Extract Hibiscus syriacus flower Extract is extracted from the flowers of Hibiscus syriacus, which has compounds that help in skin regeneration and hydration.
E3501 Hibiscus mutabilis flower Extract Hibiscus Mutabilis Flower Extract is extracted from the flowers of Hibiscus mutabilis, which has allergy-preventive effects.
L6100 HIF-1 Signaling Pathway Compound Library A unique collection of 443 HIF-1 signaling pathway compounds used for oxygen sensing related research.
S3960 Higenamine hydrochloride Higenamine (Norcoclaurine, (+-)-Demethylcoclaurine), also known as Norcoclaurine HCl, is a non-selective β2 adrenoceptor agonist which is a chemical compound naturally occurring in a number of plants.
L3500 Highly Selective Inhibitor Library A unique collection of 590 validated highly selective inhibitors with covering over 123 targets.
E0216 Hinokiflavone

Hinokiflavone, isolated from Selaginella P. Beauv, Juniperus phoenicea and Rhus succedanea, possesses excellent pharmacological activities, including anti-inflammatory, antioxidant and antitumor activity. Hinokiflavone induces apoptosis and inhibits migration of breast cancer cells via EMT signalling pathway.
S5618 Hippuric acid Hippuric Acid (2-Benzamidoacetic acid, Benzoylglycine) is an acyl glycine produced by the conjugation of benzoic acid and glycine, found as a normal component in urine as a metabolite of aromatic compounds from food.
S3296 Hispidulin Hispidulin (Dinatin), an active natrual ingredient in a number of traditional Chinese medicinal herbs, exhibits inhibitory activity against the oncogenic protein kinase Pim-1 with IC50 of 2.71 μM. Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells. Hispidulin exerts anti-osteoporotic and bone resorption attenuating effects via activating the AMPK signaling pathway.
S3968 Histamine Histamine, an organic nitrogenous compound, is involved in local immune responses regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. It is a potent H1 and H2 receptor agonist.
S4118 Histamine 2HCl Histamine(Ceplene) is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2.
S4117 Histamine Phosphate Histamine(Histamine diphosphate) acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors.
L4900 Histone modification compound library A unique collection of 347 small molecule compounds with biological activity used for histone modification research and associated assays.
S1161 Histone Acetyltransferase Inhibitor II

Histone Acetyltransferase Inhibitor II (HAT Inhibitor II, compound 2c) is a potent, selective and cell-permeable p300 histone acetyltransferase (HAT) inhibitor with IC50 of 5 μM. Histone Acetyltransferase Inhibitor II shows anti-acetylase activity in mammalian cells.
P1136 HIV Peptide T HIV Peptide T (Peptide T), a synthetic octapeptide and an antiviral agent for use in HIV infection, of which mechanism of action consists of competitive inhibition of the binding of gp120 (a surface protein of HIV) to the CD4 receptor, homologous binding to vasointestinal peptide (VIP) receptors, and blockade of cytokine production and function.
S0837 HJC0197 HJC0197 is a selective Epac 1/2 dual antagonists with an IC50 of 5.9 μM for Epac2.
S8963 HLM006474 HLM006474 is a small molecule pan-E2F inhibitor that inhibits DNA binding to E2F4 with IC50 of 29.8 µM in A375 cells. HLM006474 induces a reduction in cell proliferation and an increase in apoptosis. The CDK/Rb/E2F pathway is commonly disrupted in lung cancer, and HLM006474 is shown to have efficacy in lung cancer.
S7274 HLY78 HLY78 inhibits apoptosis in tumor cells and embryonic cells caused by carbon ion radiation through activation of the Wnt/β-catenin pathway.
S9892 HM43239

HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s' of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM, 1.8 nM and 1.0 nM, respectively.
S5807 HMN-176 HMN-176 is an active metabolite of HMN-214, which has a potent antitumor activity in mouse xenograft models. HMN-176 effectively inhibits PLK-1 by interference with its normal subcellular spatial distribution at centrosomes and along the cytoskeletal structure.
S1485 HMN-214 HMN-214 is a prodrug of HMN-176, which alters the cellular spatial orientation of Plk1.
S7501 HO-3867 HO-3867, an analog of curcumin, is a selective STAT3 inhibitor that inhibits its phosphorylation, transcription, and DNA binding without affecting the expression of other active STATs. HO-3867 induces apoptosis.
S5886 Hodostin Hodostin (Neostigmine methyl sulfate, Syntostigmin, Neostigmeth) is a reversible inhibitor of acetylcholinesterase (AChE), but can not cross the blood-brain barrier. It is used in the treatment of myasthenia gravis.
S0485 Hoechst 33342 .Hoechst 33342 (Pibenzimol, bisBenzimide H 33342, HOE 33342, HO342) is a membrane-permeant fluorescent stain that can stain live cells. Hoechst 33342 binds to adenine-thymine-rich regions of DNA in the minor groove and greatly increases the fluorescence. It allows easy visualization of the nucleus in interphase cells and chromosomes in mitotic cells.
S0486 Hoechst 34580 Hoechst 34580 (HOE 34580) is a cell-permeable blue fluorescent dye to stain DNA and nuclei. Hoechst 34580 is also a good candidate for treating the Alzheimer's disease by inhibiting amyloid beta (Aβ) formation with IC50 of 0.86 μM.
S6396 HOIPIN-1 HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM for inhibiting the in vitro linear ubiquitination activity of the petit-LUBAC.
S4025 Homatropine Bromide Homatropine Bromide is an muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.
S4024 Homatropine Methylbromide Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.
S2881 Homo-PROTAC cereblon degrader 1 Homo-PROTAC cereblon degrader 1 (OUN20985) is a potent and efficient cereblon (CRBN) degrader with minimal effects on IKZF1 and IKZF3.
S9015 Homoharringtonine (HHT) Homoharringtonine (HHT), a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression.
S9248 Homoorientin Homoorientin (Isoorientin, Luteolin-6-C-glucoside) is a flavone that acts as a radical scavenger and an antineoplastic agent.
S9417 Homoplantaginin Homoplantaginin (Hispidulin-7-glucoside), a main flavonoid from a traditional Chinese medicine Salvia plebeia, has anti-inflammatory and anti-oxidant properties. Homoplantaginin inhibits TNF-α and IL-6 mRNA expression, IKKβ and NF-κB phosphorylation.
S4572 Homosalate Homosalate (HMS, Homomenthyl salicylate) is an organic ultraviolet filter used in most sunscreens but has been reported to be toxic to marine organisms. Homosalate aggravates the invasion of human trophoblast cells as well as regulates intracellular signaling pathways including PI3K/AKT and MAPK pathways.
S5131 Homotaurine Homotaurine (Tramiprosate, Alzhemed, 3-Amino-1-propanesulfonic acid) is a synthetic organic compound that has GABAergic activity by mimicking GABA. It is a GABAA partial agonist as well as a GABAB receptor partial agonist with low efficacy.
S5642 Homovanillic acid Homovanillic acid (Vanillacetic acid) is a major catecholamine metabolite that is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain.
E3201 Honey Extract Honey extract is extracted from mel, which has been widely used for its antimicrobial property in traditional Chinese medicine.
E3583 Honeysuckle flower Extract Honeysuckle Flower Extract is extracted from the flower of Hamamelis mollis.
E3359 Honeysuckle flower Extract Honeysuckle flower Extract is extracted from Lonicera japonica Thunb, which has antibacterial, antiviral, anti-inflammatory properties.
S2310 Honokiol Honokiol is the active principle of magnolia extract that inhibits Akt-phosphorylation and promotes ERK1/2 phosphorylation. Honokiol causes G0/G1 phase arrest, induces apoptosis, and autophagy via the ROS/ERK1/2 signaling pathway. Honokiol inhibits hepatitis C virus (HCV) infection. Phase 3.
E3534 Hops Extract Hops Extract is extracted from Humulus lupulus, which is used for anxiety and mood disorders.
S2385 Hordenine Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.
E3125 Hordeum Vulgare Extract Hordeum Vulgare Extract is extracted from Hordeum vulgare, which reduces absorption of lipids as the mechanism underlying the antiobesity effect.
S3297 Hosenkoside A Hosenkoside A is a bioactive baccharane glycoside isolated from the seeds of impatiens balsamina.
S3276 Hosenkoside K Hosenkoside K is a bioactive baccharane glycoside isolated from the seeds of impatiens balsamina.
E3839 Houttuynia Cordata Extract Houttuynia Cordata Extract is extracted from Houttuynia cordata, which ameliorates bladder damage and improves bladder symptoms via anti-inflammatory effects.
E3874 Hovenia Dulcis Extract Hovenia Dulcis Extract is extracted from Hovenia dulcis, which reduces high-fat diet-induced hepatic lipid accumulation and hypertriglyceridemia.
E3872 Hovenia Dulcis Fruit Extract Hovenia Dulcis Fruit Extract is extracted from the fruits of Hovenia dulcis, which has functions such as liver protection and detoxification from alcohol poisoning.
E3873 Hovenia Dulcis Seed Extract Hovenia Dulcis Seed Extract is extracted from the seeds of Hovenia dulcis, which may be a good natural antioxidant source with protective effects on oxidative diseases such as alcoholic liver disease.
S8249 HPI-4 (Ciliobrevin A) HPI-4 (Ciliobrevin A, Hedgehog Pathway Inhibitor 4) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo.
S6060 HPK1-IN-2 HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1, a serine/threonine Ste20-related protein kinase), Lck and Flt3 with IC50 of <0.05 μM, IC50 of <0.5 μM and IC50 of <0.05 μM, respectively. HPK1-IN-2 exhibits antitumor activity.
E1339 HPPE HPPE is a specific nonelectrophilic and physiological Bach1 inhibitor via heme-binding sites of Bach1 protein, derepresses Bach1-mediated repression.
S8970 HQNO HQNO (2-heptyl-4-hydroxyquinoline-N-oxide) is a natural quinolone secreted by P. aeruginosa. HQNO is a potent inhibitor of the electron transport chain with Kd of 64 nM for the ubiquinol-ferricytochrome c oxidoreductase segment (Complex III) of the respiratory chain. HQNO is also an inhibitor of bacterial and mitochondrialType II NADH : quinone oxidoreductase (NDH-2) with IC50 of 7.3 μM in the presence of 50μM menadione.
S8775 HS-1371 HS-1371 is a potent RIP3 kinase inhibitor with an IC50 of 20.8 nM. It binds to the ATP binding pocket of RIP3 and inhibits ATP binding to prevent RIP3 enzymatic activity in vitro.
S9701 HS-243 HS-243 is a highly potent interleukin-1 receptor-associated kinase (IRAK) inhibitor with IC50 of 24 nM, 20 nM and 0.5 μM for IRAK-1, IRAK-4 and TAK1, respectively.
E1155 HS-276 HS-276, a potent and highly selective orally bioavailable transforming growth factor-β activated kinase-1 (TAK1) inhibitor with the Ki and IC50 of 2.5 nM and 2.3 nM respectively, shows significant inhibition of TNF-mediated cytokine profiles, correlating with significant attenuation of arthritic-like symptoms in the collagen-induced arthritis (CIA) mouse model of inflammatory rheumatoid arthritis (RA).
E1345 HS148 HS148 (DAPK3 inhibitor HS148) is a selective inhibitor of DAPK3 with Ki of 119 nM
E1346 HS94 HS94 (DAPK3 inhibitor HS94) is a selective inhibitor of DAPK3 with Ki of 126 nM, >20-fold selectivity over Pim kinases.
S0294 HSF1A HSF1A is a cell-permeable heat shock transcription factor 1 (HSF1) activator. HSF1A protects cells from stress-induced apoptosis, binds TRiC subunits and inhibits TRiC activity without perturbation of ATP hydrolysis.
E3746 hsian-tsao Extract Hsian-Tsao Extract is obtained from Hsian-tsao (Mesona chinensis Benth.), which is an oriental plant resource with both medicinal and edible functions.
S7097 HSP990 (NVP-HSP990) HSP990 (NVP-HSP990) is a novel, potent and selective HSP90 inhibitor for HSP90α/β with IC50 of 0.6 nM/0.8 nM. NVP-HSP990 induces cell cycle arrest and apoptosis.
S0014 HT-2157 HT-2157 (SNAP37889) is a selective, high-affinity, competitive antagonist of galanin-3 receptor (Gal3).
S5314 HTHQ (1-O-Hexyl-2,3,5-trimethylhydroquinone) HTHQ (1-O-Hexyl-2,3,5-trimethylhydroquinone), which is a hydroquinone monoalkylether, is a potent anti-oxidative and anti-lipid-peroxidative agent. HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone) has considerable anti-oxidative activity by directly reacting with reactive oxygen species (ROS), including peroxyl radicals, and scavenging them to form more stable free radicals.
L5000 HTS Library for Drug Discovery A unique collection of 99010 compounds features numerous structurally diverse compounds and several alternate compositions.
L4500 Human Endogenous Metabolite Compound Library 847 small collections of human endogenous metabolites, involving multiple metabolic pathways, which can be used for high-throughput screening, opening up new ways for humans to treat various diseases such as tumors.
L9400 Human Hormone Related Compound Library A unique collection of 454 human hormone related compounds used for high throughput screening(HTS) and high content screening(HCS).
A2051 Human IgG1 isotype control Human IgG1 isotype control is suitable for use as a non-targeting isotype control in various in vitro and in vivo studies, is the isotype control of human IgG1κ antibody.
A3176 Human IgG2sa isotype control Human IgG2sa isotype control is suitable for use as a non-targeting isotype control in various in vitro and in vivo studies, is the isotype control of human IgG2sa antibody.
A2052 Human IgG4 isotype control Human IgG4 isotype control is suitable for use as a non-targeting isotype control in various in vitro and in vivo studies, is the isotype control of human IgG4κ antibody.
L9600 Human Transcription Factor Compound Library A unique collection of 740 human transcription factor related compounds used for high throughput screening(HTS) and high content screening(HCS).
E2028 Humanin Humanin (human) (1-24-Protein humanin (human)), a small mitochondrial-derived cytoprotective polypeptide encoded by mtDNA, exhibits protective effects in several cell types against cellular stress conditions and apoptosis through regulating various signaling mechanisms, such as JAK/STAT pathway and interaction of BCL-2 family of protein.
S9475 Hupehenine Hupehenine is a steriodal alkaloid extracted from the bulbs of Fritillaria Hupehensis, with the potential for inhibiting acetylcholine, antagonism for muscarinic receptors and cholinesterase inhibition.
E2397 hVEGF-IN-1 hVEGF-IN-1, a quinazoline derivative, specifically binds to the G-rich sequence in the internal ribosome entry site A (IRES-A) with a Kd of 0.928 μM, therefore destabilizes the G-quadruplex structure, , also hinders tumor cells migration and represses tumor growth by decreasing VEGF-A protein expression.
S5865 Hyaluronic acid (Hyaluronan) Hyaluronic acid (Hyaluronan) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is widely used in skin care.
S4424 Hyaluronidase Hyaluronidase (Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase, Amphadase, Hydase, Vitrase) is a naturally occurring enzyme that degrades hyaluronic acid, which constitutes an essential part of the extracellular matrix. It depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been utilized in ophthalmic surgery.
S2562 Hydralazine HCl Hydralazine HCl is a hydrochloride salt of hydralazine, which is a direct-acting smooth muscle relaxant used to treat hypertension by acting as a vasodilator primarily in arteries and arterioles.
E2484 Hydrastine Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine), a natural alkaloid present in Hydrastis canadensis, is an inhibitor of PAK4.
S1708 Hydrochlorothiazide Hydrochlorothiazide is a first line diuretic compound of the thiazide class.
S6254 Hydrocinnamic acid Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway phenylalanine metabolism (KEGG). It is an antifungal agent and a metabolite.
S1696 Hydrocortisone Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland.
S5501 Hydrocortisone acetate Hydrocortisone Acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.
S6590 Hydrocortisone butyrate Hydrocortisone butyrate is a potent topical corticosteroid that can be used to treat a range of inflammatory skin conditions.
S5972 Hydrocortisone hemisuccinate Hydrocortisone hemisuccinate (A-hydrocort, Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid with anti-inflammatory properties, is an inhibitor of proinflammatory cytokine with IC50 of 6.7 μM and 21.4 μM for Interleukin-6 (IL-6) and IL-3, respectively.
E0177 Hydrocortisone sodium succinate

Hydrocortisone sodium succinate (Hydrocortisone 21-hemisuccinate sodium salt) has significant inhibitory effects on the IL-6 bioactivity with IC50 of 6.7 μM. Hydrocortisone sodium succinate can bind to glucocorticoid receptor, initiating the transcription of anti-inflammatory and immunosuppressive mediators.
S5135 Hydroferulic acid Hydroferulic acid (Dihydroferulic acid, Dihydroconiferylic acid) is classified as a member of the phenylpropanoic acids. It is slightly soluble in water and acidic.
E3291 Hydrolyzed Rhodophycea Extract Hydrolyzed Rhodophycea Extract is extrcated from Hydrolyzed Rhodophycea, which is a potential anticancer agent.
S9206 Hydroprotopine Hydroprotopine (W1171) is a kind of natural herbal extract.
S4658 Hydroquinidine Hydroquinidine (Dihydroquinidine, Hydroconchinine, Hydroconquinine, Dihydroquinine) is an antiarrhythmic agent.
S5114 Hydroquinine Hydroquinine (Dihydroquinine), also known as dihydroquinine, is an organic compound and as a cinchona alkaloid closely related to quinine.
S4580 Hydroquinone Hydroquinone (Quinol, 1,4-Benzenediol, 1,4-Dihydroxybenzene, HQ) is a Melanin Synthesis Inhibitor. The physiologic effect of hydroquinone is by means of Depigmenting Activity. It also posesses antioxidant properties that can cause toxicity in several organs, notably the kidney.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S3947 Hydroumbellic acid Hydroumbellic acid (2,4-Dihydroxyhydrocinnamic acid) is used as pharmaceutical intermediates.
S3898 Hydroxy Camptothecine Hydroxy Camptothecine (10-Hydroxycamptothecin, Hydroxycamptothecine) is a cell-permeable powerful DNA topoisomerase I inhibitor. It has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones.
S1846 Hydroxy-PEG4-O-Boc Hydroxy-PEG4-O-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
S4430 Hydroxychloroquine (HCQ) Sulfate Hydroxychloroquine (HCQ) Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.
S8208 Hydroxyfasudil HCl Hydroxyfasudil HCl, an active metabolite of fasudil hydrochloride, is a specific Rho-kinase(ROCK) inhibitor with IC50 values of 0.73 μM and 0.72 μM for ROCK1 and ROCK2, respectively.
S2174 Hydroxyflutamide (Hydroxyniphtholide) Hydroxyflutamide (SCH-16423, Hydroxyniphtholide) is an androgen receptor (AR) antagonist and possesses an IC50 of 0.7 μM for the androgen receptor.
S9205 Hydroxygenkwanin Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, has anti-oxidant ability and can act as tissue factor (TF) inhibitor to prevent thrombosis., Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, has anti-oxidant ability and can act as tissue factor (TF) inhibitor to prevent thrombosis.
S5672 Hydroxyhexamide Hydroxyhexamide is a pharmacologically active metabolite of acetohexamide, which is a sulfonylurea hypoglycemic agent.
S5547 Hydroxylammonium chloride Hydroxylammonium chloride (Hydroxylamine hydrochloride) is the hydrochloric acid salt of hydroxylamine, which is a biological intermediate in the nitrification and in the anammox.
S4674 Hydroxyprogesterone caproate Hydroxyprogesterone Caproate (17α-Hydroxyprogesterone hexanoate, 17α-Hydroxyprogesterone caproate) is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium.
S4115 Hydroxypropyl Cellulose Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility, it is used as food additive and sieving matrix for DNA separations.
S3826 Hydroxytyrosol Hydroxytyrosol (3,4-dihydroxyphenylethanol) is one of the main phenolic components of olive oil with excellent antioxidant, antimicrobial and anticarcinogenic activities.
S1896 Hydroxyurea Hydroxyurea is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase. Hydroxyurea activates apoptosis and autophagy. Hydroxyurea is used to treat HIV infection.
S4026 Hydroxyzine 2HCl Hydroxyzine is a histamine H1-receptor antagonist, inhibits binding of [3H]pyrilamine/[3H]desloratadine to human histamine H1 receptor with IC50 of 10 nM/19 nM.
S5649 Hydroxyzine pamoate Hydroxyzine Pamoate is the pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.
S2908 Hygromycin B Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.
S2311 Hyodeoxycholic acid (HDCA) Hyodeoxycholic (HDCA, NSC 60672) acid is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria.
S4014 Hyoscyamine Hyoscyamine (Daturine) is an AChR inhibitor with IC50 of 7.5 nM.
E0201 Hypaconitine Hypaconitine (Deoxymesaconitine) is an active diterpene alkaloid derived from Aconitum species. Hypaconitine inhibits TGF-β1-induced epithelial–mesenchymal transition.
S0911 Hypaphorine Hypaphorine which is abundantly found in vaccaria semen, counteracts inflammation via inhibition of ERK or/and NFκB signaling pathways.
S3273 Hypericin Hypericin (Hyp, HY) is a naturally occurring substance found in the common St. John's Wort (Hypericum species) with antidepressive, antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities. Hypericin has inhibitory effects on MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450).
E3695 Hypericum japonicum Extract Hypericum Japonicum Extract is obtained from the entire herb of Hypericum japonicum, has been widely used for the treatment of bacterial diseases, infectious hepatitis, acute and chronic hepatitis, gastrointestinal disorder, internal hemorrhage and tumour.
E3235 Hypericum Perforatum Extract Hypericum Perforatum Extract is extracted from Hypericum Perforatum, which has antiplatelet properties.
E3848 Hypericum Sampsonii Extract Hypericum Sampsonii Extract is extracted from Hypericum sampsonii, which induces apoptosis of cancer cells by modulating the subcellular localization of RXRalpha.
S5453 Hyperoside Hyperoside (Hyperin, Quercetin 3-galactoside), a naturally occuring flavonoid compound, exerts multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.Hyperoside can inhibit activation of the NF-κB signaling pathway.
E0010 Hypocrellin A Hypocrellin A (HA) is a perylenequinone isolated from Shiraia bambusicola that shows antiviral, antimicrobial and anticancer activity through mediating multiple signaling pathways. Hypocrellin A also is a selective and potent inhibitor of PKC.
S2424 Hypoxanthine Hypoxanthine, a naturally occurring purine derivative, an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine.
S4444 Hypromellose Hypromellose (Hydroxypropyl Methyl Cellulose, HPMC, Celacol HPM 5000) is a commonly employed cellulose ether used in the fabrication of hydrophilic matrices. Hypromellose provides the release of a drug in a controlled manner, effectively increasing the duration of release of a drug to prolong its therapeutic effect.
S3914 α-Hederin α-hederin is a water-soluble pentacyclic triterpenoid saponin which has shown hemolytic and apoptotic properties.