Home Neuronal Signaling Dopamine Receptor modulator Lithium carbonate

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Lithium carbonate Dopamine Receptor modulator

Cat.No.S4933

Lithium carbonate (Li2CO3) is an inorganic compound that is valuable and effective agent in the treatment and prophylaxis of mood disorders, particularly bipolar disorder (BD). This compound is able to alter D2 dopamine receptors response.
Lithium carbonate Dopamine Receptor modulator Chemical Structure

Chemical Structure

Molecular Weight: 73.89

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Quality Control

Batch: S493301 Water]＜1 mg/mL]false]Ethanol]＜1 mg/mL]false]5%TFA]33mg/ml mg/mL]false Purity: 98%
98

Solubility

In vitro
Batch:

Water : ＜1 mg/mL

Ethanol : ＜1 mg/mL

5%TFA : 33mg/ml mg/mL

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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Chemical Information, Storage & Stability

Molecular Weight 73.89 Formula

CLi2O3

 Storage (From the date of receipt) 3 years-21°C powder
CAS No. 554-13-2 -- Storage of Stock Solutions

Synonyms Li2CO3 Smiles [Li+].[Li+].C(=O)([O-])[O-]

Mechanism of Action

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06396312 Recruiting
Depressive; Disorder Major Single Episode Major With Psychotic Symptoms|Depressive; Disorder Major Single Episode Major (Without Psychotic Symptoms)|Depressive Disorder Major Recurrent With Psychotic Symptoms|Depressive Disorder Major Recurrent Without Psychotic Symptoms|Depressive Disorder Treatment-Resistant Class I or II|Depressive Disorder Major Moderate|Depressive Disorder Major Severe
Max-Planck-Institute of Psychiatry
 April 2 2024 --
NCT06134349 Recruiting
Bipolar Disorder
Leiden University Medical Center
 March 13 2024 --
NCT05982340 Recruiting
Acute Kidney Injury Due to Sepsis|Proximal Tubule Function|Lithium Clearance
University Hospital of North Norway
 August 1 2023 --
NCT05044611 Recruiting
Bipolar Disorder
Assistance Publique - Hôpitaux de Paris
 January 11 2023 Phase 4
NCT05648435 Completed
Acute Kidney Injury
University Hospital of North Norway
 December 7 2022 --

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