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Lactate

Name: Lactate
Brand: Selleck Chemicals
SKU: E4473
Availability: InStock
Rating: 5 (2 reviews)

Cat.No.E4473

Lactate (Lactic acid) is the product of glycolysis, produced due to lack of oxygen in contracting skeletal muscle in vivo, and can be utilised under fully aerobic conditions. It plays a key role as a metabolic intermediate and can be used as hemodynamic marker and resuscitation endpoint in several cohorts of critically ill patients.

Chemical Structure

Molecular Weight: 90.08

Jump to Mechanism of Action Chemical Information, Storage & Stability

Quality Control

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Chemical Information, Storage & Stability

Molecular Weight	90.08	Formula	C₃H₆O₃	Storage (From the date of receipt)	2 years -20°C liquid
CAS No.	50-21-5	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

References	[1] https://pubmed.ncbi.nlm.nih.gov/17465603/ [2] https://pubmed.ncbi.nlm.nih.gov/22517402/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT05731050	Not yet recruiting	PNH - Paroxysmal Nocturnal Hemoglobinuria	NovelMed Therapeutics	June 2025	Phase 2
NCT05646563	Not yet recruiting	Paroxysmal Nocturnal Hemoglobinuria	NovelMed Therapeutics	March 2025	Phase 2
NCT05036122	Not yet recruiting	Healthy	Mayo Clinic	February 2025	Not Applicable
NCT06384469	Not yet recruiting	Rhinoplasty\|Nasal Skin-soft Tissue Envelope Metabolism\|Lactic Acid\|Autologous Cartilage Grafting	University Hospital Sestre Milosrdnice	January 2 2025	--
NCT05646524	Not yet recruiting	Paroxysmal Nocturnal Hemoglobinuria	NovelMed Therapeutics	January 2025	Phase 2
NCT02785224	Not yet recruiting	Cardiac Arrest	University of Athens\|University of Thessaly	December 2024	--

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