Angiogenesis is the physiological process of the growth of new blood vessels from pre-existing vessels. Angiogenesis can be induced by solid tumor growth. In the meantime, angiogenesis provides solid tumor with oxygen and nutrients to make it reach a certain size.There are many important targets related to angiogensis including EGFR, HER2, VEGFR, PDGFR, FGFR, FLT3, HIF, ALK, VDA, S1P receptor. Most of those targets are receptor tyrosine kinases (RTK)s.
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