Histone modification compound library

Catalog No.L4900

Offered in 96 or 384 well plate format

A unique collection of 226 small molecule compounds with biological activity used for histone modification research and associated assays.

Size Price  
Pre-dissolved In DMSO or Water
USD 7131

Selleck Chemicals compound library contributes and expedites
the investigation of treatments against COVID19

The researchers at the National Institute of Infectious Diseases, in Japan, successfully found anti-COVID19 drugs within 3 months of
screening FDA-approved drug library from Selleck Chemicals. They have already published this article doi: 10.1101/2020.04.14.039925.

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Histone modification compound library Contents

Download the Histone modification compound library - SDF
Download the Histone modification compound library - XLSX
Download the Compound Library Usage Instructions-pdf

Cited by 125 Publications

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer
    Nature.2019;574(7777):268-272
  • Application of Kinase Inhibitor Library in colorectal cancer
    Nat Commun. 2019 16;10(1):2197
  • Application of FDA-approved Drug Library in antivirus
    Cell Res. 2019;29(9):739-753
  • Application of FDA-approved Drug Library in metabolism
    Mov Disord. 2019;34(3):323-334
  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia
    Blood. 2019 17;134(16):1323-1336
  • Application of Inhibitor Library in tumor immunology
    Cancer Immunol Res.2017;5(9):790-803

Description & Advantages

• A unique collection of 226 small molecule compounds for high throughput screening(HTS) and high content screening (HCS).
 
• A useful tool for histone modification research and associated assays
 
• Targets Epigenetic Reader Domain, HDAC, Histone Methyltransferase, Histone Demethylase and Histone Acetyltransferase
 
• For studying human diseases, exploring the pathogenesis of diseases
such as cancer, and opening noval therapeutic ways 
 
• Structurally diverse, medicinally active, and cell permeable
 
• Rich documentation with structure description, target information, IC50
 values and customer reviews
 
• NMR and HPLC validated to ensure high purity

 

Product Details

Formulation: 220 compounds pre-dissolved in 10mM DMSO, 1 compound pre-dissolved in 10mM water and 5 compounds pre-dissolved in 2mM DMSO
Container: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability: in DMSO
in DMSO
Shipping: Blue ice or dry ice
Packaging: Inert gas

Histone modification compound library Composition

HTS Facility Partners

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