All Products

Catalog No. Product Name Information
S8337 1400W 2HCl 1400W (N-(3-(Aminomethyl)benzyl)acetamidine) is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase(iNOS).
S0409 5WKS 5WKS (ZINC97756584) is an active biochemical.
E0382 W-84 Dibromide W-84 dibromide (HDMPPA) is a potent allosteric modulator of M2-acetylcholine receptors, which retards 3HN-methylscopolamine dissociation.
E3259 Walnut Extract
E3262 Walnut Leave Extract
S0195 Walrycin B Walrycin B is an antibacterial compound and a potent inhibitor of WalR targeting the WalR response regulator.
S9485 Waltonitone Waltonitone, an ursane-type pentacyclic triterpene extracted from Gentiana waltonii Burkill, exerts anti-tumor effect.
S4545 Warfarin Warfarin (Athrombine K, Coumadin, Coumafene, WARF 42, Zoocoumarin) is one of the most widely used anticoagulant drugs worldwide, used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body.
E3162 Wax Gourd Peel Extract
S2663 WAY-100635 Maleate WAY-100635 Maleate is a potent and selective 5-HT receptor antagonist with IC50 of 0.95 nM.
E0798 WAY-119064 WAY-119064 is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 value of 80.5 nM.
S3458 WAY-169916 WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER) that acts by inhibiting NF-kB transcriptional activity.
S0143 WAY-200070 WAY-200070 is a selective estrogen receptor β (ERRβ) agonist with an IC50 of 2.3 nM.
S5892 WAY-213613 WAY-213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC50 of 85 nM for excitatory amino acid transporter subtype 2 (EAAT2).
S9828 WAY-262611 WAY-262611 (BML-WN110, Compound 5) is a beta-catenin (β-Catenin) agonist that increases bone formation rate with EC50 of 0.63 μM in TCF-Luciferase assay. WAY-262611 is also an inhibitor of dickkopf 1 (DKK1).
E2133 WAY-272077
E2808 WAY-296817
E2518 WAY-297342
E2137 WAY-297407 WAY-297407 is a bioactive compound licensed by Pfizer.
E2509 WAY-297848 WAY-297848 is a novel glucokinase activator with potential use as a drug for the prevention or treatment of hyperglycemia, diabetes, obesity, dyslipidemia, metabolic syndrome, etc.
E2510 WAY-301398 WAY-301398 (6-methoxynaphthalene) can bind to protein kinase C (PKC).
E0535 WAY-303290 WAY-303290 (GluR6 antagonist-1) is a benzothiophene derivative acting as an ionotropic glutamate receptor 6 (GluR6) antagonist, which can be used for researching acute and chronic neurological disorders.
E0536 WAY-309060
E1209 WAY-309236-A
S5815 WAY-316606 WAY-316606, a specific antagonist of SFRP1, functions as an activator of canonical Wnt/β-catenin signalling in the human hair bulb.
E2521 WAY-327157 WAY-327157 is a bioactive compound licensed by Pfizer.
E0534 WAY-340935 WAY-340935 (VEGFR2-IN-2) can inhibit the function of VEGFR2 and the anti-proliferative activity against the H460 cell line is produced partly by interaction of VEGFR protein.
E2522 WAY-345989 WAY-345989 is a bioactive compound licensed by Pfizer.
S7859 WAY-354831
E2520 WAY-358871 WAY-358871 is a bioactive compound licensed by Pfizer.
E0797 WAY-383487 WAY-383487 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.
E2517 WAY-388264-A WAY-388264-A is a bioactive compound licensed by Pfizer.
E2508 WAY-608241 WAY-608241 is a bioactive compound licensed by Pfizer.
E2135 WAY-620645 WAY-297407 is a bioactive compound licensed by Pfizer.
E2519 WAY-624704 WAY-624704 is a novel Rho kinases (ROCK) inhibitor with an Ki of 17 nM.
E2524 WAY-639418 WAY-639418 is a bioactive compound licensed by Pfizer.
E0537 WAY-659694 WAY-659694 is a bioactive compound licensed by Pfizer.
S2184 WDR5-0103 WDR5-0103 (WD-Repeat Protein 5-0103) is a small-molecule antagonist of WDR5 (WD40 repeat protein 5) with Kd of 450 nM.
E3532 Wedelia Extract
S9042 Wedelolactone Wedelolactone, a medicinal plant-derived natural compound, is an inhibitor of IKK that is critical for activation of NF-κB by mediating phosphorylation and degradation of IκBα. Wedelolactone is also an inhibitor of caspase-11.
S7100 WEHI-539 HCl WEHI-539 HCl (WEHI-539 hydrochloride) has high affinity (IC50=1.1 nM) and selectivity for BCL-XL and potently kills cells by selectively antagonizing its prosurvival activity. It has more than a 400-fold higher affinity for BCL-XL versus other prosurvival BCL-2 family members.
S0393 WEHL-03 WEHL-03 is an active compound.
S0394 WEHL-04 WEHL-04 (7-Bromo-1,2,3,4-tetrahydroquinoline) is an active compound.
E3365 Weigela Grandiflora Fortune Extract
S7565 WH-4-023 WH-4-023 (KIN001-112, KIN112, Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.
E3770 Wheat Germ Extract
S2867 WHI-P154 WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation.
S6520 WHI-P180 WHI-P180 is a multi-kinase inhibitor with IC50 values of 4.5 and 66 nM for the human proto-oncogene RET (c-RET) and kinase insert domain receptor (KDR), respectively.
S6521 WHI-P258 WHI-P258 is an inhibitor of JAK3 with Ki value of 72 μM.
S5904 WHI-P97 WHI-P97 is a potent inhibitor of JAK-3 with an estimated Ki value of 0.09 μM in modeling studies and a measured IC50 value of 2.5 μM in EGFR kinase inhibition assays.
E3038 White Kidney Bean Extract
E3595 White mulberry root-bark Extract
E3023 White Mustard Seed Extract
E3029 White Paeony Root Extract
E3208 White Prepared Lateral Root of Aconite Extract
E3026 White Radish Extract
E3014 White Tea Extract
S7490 WIKI4 WIKI4 is a novel Tankyrase inhibitor with IC50 of 15 nM for TNKS2, and leads to inhibition of Wnt/beta-catenin signaling.
S0973 Wilforgine Wilforgine, one of the major bioactive sesquiterpene alkaloids in Tripterygium wilfordii Hook. F., induces microstructural and ultrastructural changes in the muscles of M. separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system.
S0921 Wilforine Wilforine (WR), a sesquiterpene pyridine alkaloid found in T. wilfordii plants, significantly inhibits the efflux activity of P-glycoprotein (P-gp).
S6428 Wilforlide A Wilforlide A is an active compound in Tripterygium wilfordii Hook F (TW) which is a traditional Chinese medicine for treatment of autoimmune diseases.
S8017 WIN 55, 212-2 mesylate WIN 55,212-2 Mesylate ((R)-(+)-WIN 55212) is a potent cannabinoid (CB) receptor agonist with Ki of 3.3 nM and 62.3 nM for human recombinant CB2 and CB1, respectively. WIN 55,212-2 Mesylate regulates Glutamate transmission.
E3356 Witch hazel Extract
S8587 Withaferin A Withaferin A (WA, WFA) potently inhibits NF-κB activation by preventing the tumor necrosis factor-induced activation of IκB kinase β via a thioalkylation-sensitive redox mechanism. Withaferin A binds to the intermediate filament (IF) protein, vimentin with antitumor and antiangiogenesis activity. Withaferin A is a steroidal lactone isolated from Withania somnifera.
S6353 Withanolide A Withanolide A is a natural compound isolated from the indian herbal drug Ashwagandha (root of Withania somnifera). Withanolide A can regenerate neurites and reconstruct synapses in severely damaged neurons.
S2976 WJ460 WJ460 is a potent inhibitor of myoferlin (MYOF) that interacts directly with MYOF and exerts anti-metastatic activity in the nanomolar range in breast cancer cells.
S9805 WM-3835 WM-3835 is a novel and high-specific small molecule Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) inhibitor, able to potently suppressed OS cell proliferation and migration, and leads to apoptosis activation.
S6655 WM-8014 WM-8014 is a highly potent inhibitor of histone acetyltransferase KAT6A with an IC50 of 8 nM.
S0015 WNK-IN-11 WNK-IN-11 is a potent, selective, and orally acitve allosteric inhibitor of With-No-Lysine (WNK) kinase with IC50 of 4 nM for WNK1 enzyme.
S8358 WNK463 WNK463 is a pan-WNK-kinase inhibitor. It potently inhibits the in vitro kinase activity of all four WNK family members (WNK1, WNK2, WNK3, and WNK4).
S8178 Wnt agonist 1 Wnt agonist 1 (BML-284 HCL, AMBMP HCL) is a cell permeable Wnt signaling pathway activator, which induces β-catenin- and TCF-dependent transcriptional activity with EC50 of 0.7 μM.
S7037 Wnt-C59 (C59) Wnt-C59 (C59) is a PORCN inhibitor for Wnt3A-mediated activation of a multimerized TCF-binding site driving luciferase with IC50 of 74 pM in HEK293 cells.
S4743 Wogonin Wogonin (Vogonin), a natural and biologically-active flavonoid found in plants, is an inhibitor of CDK9 and does not inhibit CDK2, CDK4 and CDK6 at doses that inhibit CDK9 activity; Also inhibits N-acetyltransferase.
S9115 Wogonoside Wogonoside (Oroxindin, Wogonin 7-O-glucuronide, Glychionide B), the main flavonoid component derived from the root of Scutellaria baicalensis Georgi, displays anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities.
E2560 Worenine

Worenine, one of the bioactive components isolated from <i>Coptis chinensis</i>, shows dehydrogenization, hydrogenation, hydroxylation and demethylene reactions in phase I metabolism, sulfation and glucuronidation in phase II metabolism in rat.

E3386 Wormwood Extract
S2758 Wortmannin (KY 12420) Wortmannin (KY 12420, SL-2052, BRN 0067676, NSC 627609) is the first described PI3K inhibitor with IC50 of 3 nM in a cell-free assay, with little selectivity within the PI3K family. Wortmannin blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM in cell-free assays. Wortmannin also inhibits PLK1 activity.
S2796 WP1066 WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. WP1066 induces apoptosis. Phase 1.
E0388 WQ 1 WQ 1 is a high affinity and selective σ1 receptor antagonist with pKi values of 10.85, 6.53 and 5.80 at σ1, σ2 receptors and dopamine transporter (DAT), displaying σ1/σ2 selectivity ratio of 20893.
S9818 WRW4 WRW4 is a specific formyl peptide receptor-like 1 (FPRL1) antagonist that inhibits WKYMVm binding to FPRL1 with IC50 of 0.23 μM. WRW4 is a selective antagonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX).
S2963 WS-12 WS-12 is a potent TRPM8 agonist with an EC50 of 39 nM.
S7764 WST-8 WST-8 is a water-soluble tetrazolium salt used for assessing cell metabolic activity that produces corresponding formazan dye that absorbs at 460 nm. WST-8 is typically used as a cell viability indicator in cell proliferation assays.
S8495 WT161 WT161 is a potent, selective, and bioavailable HDAC6 inhibitor with IC50 values of 0.4 nM, 8.35 nM and 15.4 nM for HDAC6, HDAC1 and HDAC2, respectively; shown to have >100-fold selectivity over other HDACs. WT161 induces apoptosis.
S3182 WUN-29654

WUN-29654 (CRBN modulator-1, compound 10) is a Thalidomide analog and a CRBN modulator with IC50 of 3.5 μM and Ki of 0.98 μM for CRBN binding.

S0967 Wushanicaritin Wushanicaritin exhibits antioxidant activity with IC50 of 35.3 μM in DPPH radical scavenging activity tests. Wushanicaritin has antitumor effects and anti-inflammatory property. Wushanicaritin is isolated from the traditional Chinese medicine Epimedium plants.
S5896 WWL-154 WWL-154 is an inhibitor of serine hydrolase (SH) and fatty acid amide hydrolase FAAH-4.
S3487 WWL229 WWL229 is a selective inhibitor of Ces3 that acts by inhibiting recombinant Ces3 and recapitulating the effects of WWL113 in adipocytes.
S8029 WY-14643 (Pirinixic Acid) WY-14643 (Pirinixic Acid, NSC 310038) is a potent and selective PPARα activator with an EC50 of 1.5 μM.
S0317 WYC-209 WYC-209 is a synthetic retinoid and an agonist of retinoic acid receptor (RAR). WYC-209 induces apoptosis primarily via the caspase 3 pathway with IC50 of 0.19 μM for inmalignant murine melanoma TRCs. WYC-209 has long-term effects with little toxicity.
S2661 WYE-125132 (WYE-132) WYE-125132 (WYE-132) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR.