CNS-Penetrant Compound Library

Catalog No.L4700

Offered in 96 or 384 well plate format

A unique collection of 734 CNS-Penetrant compounds with biological activity for neurologic research.

Selleck Chemicals compound library contributes and expedites
the investigation of treatments against COVID19

The researchers at the National Institute of Infectious Diseases, in Japan, successfully found anti-COVID19 drugs within 3 months of
screening FDA-approved drug library from Selleck Chemicals. They have already published this article doi: 10.1101/2020.04.14.039925.

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CNS-Penetrant Compound Library Contents

Cited by 206 Publications

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer
  • Application of Kinase Inhibitor Library in colorectal cancer
    Nat Commun. 2019 16;10(1):2197
  • Application of FDA-approved Drug Library in antivirus
    Cell Res. 2019;29(9):739-753
  • Application of FDA-approved Drug Library in metabolism
    Mov Disord. 2019;34(3):323-334
  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia
    Blood. 2019 17;134(16):1323-1336
  • Application of Inhibitor Library in tumor immunology
    Cancer Immunol Res.2017;5(9):790-803

Description & Advantages

• A unique collection of 734 small molecule compounds with biological activity used for neurologic research and associated assays

•Targets 5-HT Receptor,DHFR,COX,RAAS,AChR etc

• Some compounds have been approved by the FDA

• Structurally diverse, medicinally active, and cell permeable

• Rich documentation with structure, IC50, and customer reviews

• NMR and HPLC validated to ensure the highest purity

Product Details

Formulation: 671 compounds pre-dissolved in 10mM DMSO, 39 compounds pre-dissolved in 10mM water, 22 compounds pre-dissolved in 2mM DMSO and 2 compounds pre-dissolved in 2mM water
Container: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability: in DMSO
Shipping: Blue ice or dry ice

CNS-Penetrant Compound Library Composition

HTS Facility Partners

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