Catalog No.S1357 Synonyms: Alphacaine

For research use only.

Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

Lidocaine Chemical Structure

CAS No. 137-58-6

Selleck's Lidocaine has been cited by 6 Publications

Purity & Quality Control

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Biological Activity

Description Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
Histamine H1 receptor [1]
>32 μM

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 234.34


CAS No. 137-58-6
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CCN(CC)CC(=O)NC1=C(C=CC=C1C)C

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04614610 Not yet recruiting Drug: Lidocaine Iv|Drug: Placebo Sickle Cell Disease|Sickle Cell Crisis|Pain Acute Community Medical Center Toms River NJ|Newark Beth Israel Medical Center|Monmouth Medical Center|Rutgers Robert Wood Johnson Medical School October 1 2022 Phase 2
NCT05402293 Not yet recruiting Diagnostic Test: Blood samples to measure lidocaine levels Acute Pain|Lidocaine|Administration and Dosage University of Alberta August 1 2022 --
NCT05379283 Not yet recruiting Drug: Lidocaine|Other: control Sweat Pore Closure San Diego State University May 15 2022 Not Applicable
NCT05238506 Recruiting Drug: Intravenous lidocaine|Drug: Normal saline infusion Hemodynamic Response|Acute Appendicitis|Complication of Treatment|Opioid Consumption|Pneumoperitoneum Medical University of Warsaw March 12 2022 Phase 4

(data from, updated on 2022-08-01)

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