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Catalog No.S1357 Synonyms: Alphacaine

4 publications

Lidocaine Chemical Structure

CAS No. 137-58-6

Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

Size Price Stock Quantity  
10mM (1mL in DMSO) RMB 1066.72 In stock
RMB 792.52 In stock
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Biological Activity

Description Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
Histamine H1 receptor [1]
>32 μM


Solubility (25°C)

In vitro DMSO 47 mg/mL (200.56 mM)
Water 9 mg/mL (38.4 mM)
Ethanol '47 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 234.34


CAS No. 137-58-6
Storage powder
in solvent
Synonyms Alphacaine
Smiles CCN(CC)CC(=O)NC1=C(C=CC=C1C)C

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03095404 Not yet recruiting Drug: Low Dose Lidocaine|Drug: High Dose Lidocaine Bariatric Surgery Candidate McMaster University|St. Joseph''s Healthcare Hamilton September 2020 Early Phase 1
NCT04192773 Not yet recruiting Drug: IV Lidocaine Tinnitus Massachusetts Eye and Ear Infirmary August 2020 Early Phase 1
NCT04359017 Not yet recruiting Drug: Lidocaine 1% Injectable Solution Radius Fracture Distal|Hematoma|Lidocaine|Pediatrics Washington University School of Medicine August 2020 Phase 4

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Histamine Receptor Signaling Pathway Map

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