research use only

Linoleic acid

Name: Linoleic acid
Brand: Selleck Chemicals
SKU: S5821
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.S5821

Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid used in the biosynthesis of arachidonic acid and found in the lipids of cell membranes.,

Quality Control

Batch: S582102 DMSO]56 mg/mL]false]Ethanol]56 mg/mL]false]Water]Insoluble]false Purity: 100.00%

Cited in Nature Medicine for its top-tier quality
COA
SDS/MSDS
Datasheet

100.00

Related Targets	PROTAC Dyes Antineoplastic and Immunosuppressive Antibiotics ADC Cytotoxin Selection Antibiotics for Transfected Cell Antibiotics for Mammalian Cell Culture ADC Linker Molecular Glues Hydrotropic Agents Antibiotics for Plant Cell Culture
Other Others Inhibitors	Furimazine (PBI 3939) Guanidinoacetic acid Blebbistatin Polybrene (Hexadimethrine Bromide) Silibinin (NSC 651520) Palmitic acid Carbazochrome sodium sulfonate (AC-17) 4-Methylumbelliferone (4-MU) Sesamin Osthole

Solubility

In vitro
Batch:

DMSO : 56 mg/mL (199.67 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 56 mg/mL

Water : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	2.800mg/ml (9.98mM)	Taking the 1 mL working solution as an example, add 50 μL of 56 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	0.700mg/ml (2.50mM)	Taking the 1 mL working solution as an example, add 50 μL of 14 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	280.45	Formula	C₁₈H₃₂O₂	Storage (From the date of receipt)	2 years -20°C(in the dark) liquid
CAS No.	60-33-3	--		Storage (From the date of receipt)	2 years -20°C(in the dark) liquid
Synonyms	9,12-octadecadienoic acid			SMILES	CCCCCC=CCC=CCCCCCCCC(=O)O

Read more about storage stability CAS number SMILES

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-04-21)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date
NCT06361511	RECRUITING	Sarcopenia	Ohio State University	2025-04-16
NCT04677946	NOT_YET_RECRUITING	Insomnia Type; Sleep Disorder	Ohio State University	2027-12
NCT02841618	ACTIVE_NOT_RECRUITING	Healthy Adults	Ohio State University	2016-01
NCT04677920	ACTIVE_NOT_RECRUITING	Healthy Adults	Ohio State University	2020-09-07
NCT07287514	RECRUITING	Insulin Resistance; Metabolic Disease	Pontificia Universidad Catolica de Chile	2025-05-13
NCT05920018	UNKNOWN	Multiple Sclerosis, Relapsing-Remitting	Universität Münster	2023-10-02

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):