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Catalog No.	Product Name	Information
S3611	(+)-Fangchinoline	Fangchinoline ((+)-Limacine, Tetrandrine B, Hanfangichin B) is a phytochemical that has been shown to elicit anti-cancer effects in prostate and breast cancer cell lines via inducing G1 cell cycle arrest. It has also been shown to possess neuroprotective activity.
S5934	(-)-Fenchone	Fenchone is a constituent of absinthe and the essential oil of fennel. It is used as a flavor in foods and in perfumery.
S6107	1-Furfurylpyrrole	1-Furfurylpyrrole (N-Furfurylpyrrole) is a potential contributor of flavor and aroma to popcorn.
S7153	10058-F4	10058-F4 is a c-Myc inhibitor that specificallly inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression. 10058-F4 promotes a caspase-3-dependent apoptosis and modulates autophagy.
S6320	2,5-Furandicarboxylic acid	2,5-Furandicarboxylic acid (Dehydromucic acid) is a normal urinary metabolite in humans and an important renewable building block because of its potential as a substitute for a variety of petrochemicals, such as terephthalic acid and adipic acid.
S4864	2-Furoic acid	2-Furoic acid (2-Furancarboxylic acid, Pyromucic acid, 2-Carboxyfuran, α-furancarboxylic acid, α-furoic acid) is an organic compound most widely found in food products as a preservative and a flavoring agent.
S6848	3'-Fluoro-3'-deoxythymidine (Alovudine)	3'-Fluoro-3'-deoxythymidine (Alovudine, CL 184824, FddThd, FLT, MIV-310) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer.
S6097	3-Furoic acid	3-Furoic acid is an organic acid regularly occurring in urine of healthy individuals.
E0070	4F 4PP oxalate	4F 4PP oxalate is an antagonist of the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 5.3 nM), which is selective for 5-HT2A receptors over 5-HT1C receptors (Ki = 620 nM).
S0550	5'-Fluoroindirubinoxime	5'-Fluoroindirubinoxime (5’-FIO, compound 13), an indirubin derivative, is a potent FLT3 inhibitor, with an IC50 of 15 nM.
S9873	5-Fluoroorotic acid	5-Fluoroorotic acid (5-FOA, 5-Fluoroorotate, NSC 31712) is a selective agent in yeast molecular genetics. 5-Fluoroorotic acid possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects.
S1209	5-FU (5-Fluorouracil)	5-FU (5-Fluorouracil) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.
S0302	F1063-0967	F1063-0967 is an inhibitor of Dual-specificity phosphatase 26 (DUSP26) with IC50 of 11.62 μM.
S2474	Fabomotizole hydrochloride	Fabomotizole hydrochloride (Fabomotizole, CM346, CM346, Afobazol, Afobazole) exhibits anxiolytic and neuroprotective properties. Fabomotizole hydrochloride is a potent sigma1-receptor agonist with IC50 of 7.1 µM and Ki of 5.9 µM.
S7371	Fadraciclib (CYC065)	Fadraciclib (CYC065) is a novel, orally available ATP-competitive inhibitor of CDK2/CDK9 kinases with IC50 of 5 nM and 26 nM, respectively.
S9519	Fadrozole (CGS16949A)	Fadrozole (CGS16949A) is a potent, selective, nonsteroidal inhibitor of aromatase with an IC50 of 4.5 nM and selectivity over other cytochrome P-450 enzymes.
E3733	Faeces Trogopterori Extract	Faeces Trogopterori Extract is derived from the faeces of the complex-toothed flying squirrel Trogopterus xanthipes Milne-Edwards.
S3292	Falcarindiol	Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) is a natural polyacetylene compound found rich in many plants of the Umbelliferae family. Falcarindiol suppresses LPS-stimulated expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNFα), interleukin-6 (IL-6), and interleukin-1 beta (IL-1β). Falcarindiol attenuates the LPS-induced activation of JNK, ERK, STAT1, and STAT3 signaling molecules.
E2399	Falnidamol	Falnidamol (BIBX1382) is a selective inhibitor of epidermal growth factor receptor (EGFR), exerting anti-cancer role in human head and neck squamous cell carcinomas both in vitro and in vivo through suppressing mitogen-activated protein kinases (MAPKs) signaling.
S2467	Famciclovir	Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.
S2078	Famotidine	Famotidine (MK208) is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.
S4327	Famprofazone	Famprofazone (Geodowin, FA, Famprofazonum) is a non-steroidal anti-inflammatory agent (NSAID) of the pyrazolone series. Famprofazone is an analgesic used for fever and pain relief.
S3606	Fangchinoline	Fangchinoline, a bisbenzylisoquinoline alkaloid, is a novel HIV-1 inhibitor with pain-relieving, blood pressure-depressing, and antibiotic activities.
S9285	Fargesin	Fargesin is a neolignan isolated from Magnolia plants. It is a potential β1AR antagonist through cAMP/PKA pathway.
D4015	Farletuzumab-MMAE	Farletuzumab-MMAE is an antibody-drug conjugate (ADC) composed of humanized anti-human folate receptor-alpha (FRα) and the cytotoxic agent monomethyl auristatin (MMAE) via a MC-Vc linker. It has a potent antitumor activity.
S4941	Farnesol	Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects.
S6150	Farnesyl Acetate (mixture of isomers)	Farnesyl Acetate is a flavouring compound identified in foods such as blueberries.
S4847	Faropenem Sodium	Faropenem sodium is an orally active beta-lactam antibiotic that has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.
S9552	Farrerol	Farrerol, an important bioactive constituent of rhododendron, exhibits broad activities such as anti-oxidative and anti-inflammatory effects.
S9721	Farudodstat	Farudodstat(LAS 186323,ASLAN003) is a potent and orally active inhibitor of DHODH (Dihydroorotate dehydrogenase) with IC50 of 35 nM for human DHODH enzyme activity. ASLAN003 impairs protein synthesis and induces the differentiation and apoptosis transcriptional program in acute myeloid leukemia (AML) cells via activation of AP-1 transcription factors.
S2637	Fasiglifam(TAK-875) Hemihydrate	Fasiglifam(TAK-875) Hemihydrate is a selective GPR40 agonist with EC50 of 14 nM in human GPR40 expressing CHO cell line, 400-fold more potent than oleic acid.
S6248	Fasnall	Fasnall, a thiophenopyrimidine, is a selective fatty acid synthase (FASN) inhibitor that shows potent anti-tumor activity.
E1773	Fasoracetam (NS 105)	Fasoracetam (NS 105) is a metabotropic glutamate receptor activator with a potential to treat vascular dementia.
E2913	Fast Green FCF	Fast Green FCF (FD&C Green No. 3; Food green 3; C.I. 42053) is a sea green triarylmethane food dye. It is a dye used to stain proteins for IEF (isoelectric focusing) and SDS-PAGE. When bound to proteins, Fast Green FCF fluoresces near infrared (absorption maximum: 624 nm). Fast Green FCF staining is linear over a wider range of protein concentrations compared to Brilliant Blue R.
S1573	Fasudil HCl	Fasudil HCl, a potent and selective inhibitor of Rho kinase, displays less potent inhibiton over PKA, PKG, PKC and MLCK with Ki of 1.6, 1.6, 3.3, and 36 μM in cell-free assays, respectively. Fasudil is also a calcium channel blocker.
E2950	Fat Emulsion（20%）	Fat Emulsion（20%）is a safe fat emulsion that can be used as a nutritional supplement. Fat Emulsion（20%）inhibits the opening of the mitochondrial permeability transition pore and effectively protecting the heart from ischaemia-reperfusion injury. It has some potential to modulate the innate immune response.
S9785	Fatostatin	Fatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells.
S8284	Fatostatin HBr	Fatostatin HBr is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.
S7975	Favipiravir (T-705)	Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.
S6291	FB23	FB23 is a potent and selective inhibitor of FTO demethylase with IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.
S8837	FB23-2	FB23-2 is a potent and selective FTO inhibitor that directly binds to FTO and selectively inhibits FTO's N⁶-methyladenosine (m⁶A) demethylase activity with IC50 of 2.6 μM.
E2846	FBPase-1 inhibitor-1	FBPase-1 inhibitor-1, an allosteric inhibitor of fructose-1,6-bisphosphatase (FBPase-1), exhibits similar potency (IC50 = 3.4 μM using MG; = 4.0 μM in the coupled format) in these two distinct assays of FBPase-1 activity.
S8276	FCCP	FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone, Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone) is a potent uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP synthesis by transporting protons across cell membranes.
L3800	FDA-approved & Passed Phase I Drug Library	A unique collection of 3621 drugs that are marketed around the world or have passed clinical phase 1 and can be used for high throughput screening (HTS) and high content screening (HCS).
L8000	FDA-approved Anticancer Drug Library	A unique collection of 1746 approved drugs with potential anticancer activity used for high throughput screening(HTS) and high content screening(HCS).
L1300	FDA-approved Drug Library	A unique collection of 3109 approved drugs and API included in pharmacopoeia for high throughput screening (HTS) and high content screening (HCS).
S9689	FDI-6	FDI-6 (NCGC00099374) is an inhibitor of the Forkhead box protein M1 transcription factor (FOXM1) with IC50 of 22.5 μM.
S8795	FDL169	FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein.
S5092	Febantel	Febantel (Rintal, Combotel, Oratel, Bay Vh 5757, Negabot Plus) is a prodrug that is metabolized to fenbendazole and oxfendazole, which are undoubtedly the active parasiticides.
S1547	Febuxostat	Febuxostat (TMX 67, TEI-6720) is a selective xanthine oxidase inhibitor with K_i of 0.6 nM.
S2736	Fedratinib (TG101348)	Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Fedratinib also inhibits FMS-like tyrosine kinase 3 (FLT3) and RET (c-RET) with IC50 of 15 nM and 48 nM, respectively. Fedratinib has potential antineoplastic activity. Fedratinib inhibits proliferation and induces apoptosis. Phase 2.
S1330	Felbamate	Felbamate (Felbatol, ADD-03055,W-554) is an anticonvulsant drug used in the treatment of epilepsy; NMDAR antagonist.
S1885	Felodipine	Felodipine (CGH-869) is a selective L-type Ca²⁺ channel blocker with IC50 of 0.15 nM.
P1047	Felypressin Acetate	Felypressin-Acetate is a non-catecholamine vasoconstrictor that is chemically associated to vasopressin, the posterior pituitary hormone.
S3397	FEN1-IN-4	FEN1-IN-4 (FEN1 Inhibitor C2, JUN93587, Compound 2) is an inhibitor of human flap endonuclease-1 (hFEN1) with IC50 of 30 nM for hFEN1-336Δ.
S5517	Fenamic acid	Fenamic acid (N-Phenylanthranilic acid, 2-(Phenylamino)benzoic acid, 2-Anilinobenzoic acid, Diphenylamine-2-carboxylic acid) serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid.
S2468	Fenbendazole	Fenbendazole(Fenbendazol,Phenbendasol) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.
S4526	Fenbufen	Fenbufen (Lederfen, CL-82204) is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.
S5379	Fenchyl Alcohol	Fenchyl Alcohol is used as a flavoring agent to provide a pine, herbal, lemon, or floral taste to food and drink.
S5279	Fendiline hydrochloride	Fendiline hydrochloride is the hydrochloride salt form of Fendiline, which is an L-type calcium channel blocker and also a specific inhibitor of K-Ras plasma membrane targeting with no detectable effect on the localization of H- and N-Ras.
S8421	Fenebrutinib (GDC-0853)	Fenebrutinib (GDC-0853) is a potent, selective, and non-covalent bruton's tyrosine kinase (BTK) inhibitor with an Ki value of 0.91 nM for Btk with >100-fold selectivity over 3 off-targets (Bmx :153-fold, Fgr: 168-fold, Src:131-fold).
S5702	Fenipentol	Fenipentol (1-phenylpentan-1-ol, 1-Phenyl-1-pentanol, 1-Phenylpentanol) is a member of benzenes and stimulates plasma secretion & exocrine pancreatic secretion.
S1794	Fenofibrate	Fenofibrate is a compound of the fibrate class and fibric acid derivative. Fenofibrate is a selective agonist of PPARα with EC50 of 30 μM. Fenofibrate binds to and inhibits cytochrome P450 epoxygenase (CYP)2C with IC50 of 0.2 μM, 0.7 μM and 9.7 μM for CYP2C19, CYP2B6 and CYP2C9, respectively. Fenofibrate induces autophagy.
S4527	Fenofibric acid	Fenofibric acid (NSC 281318, Trilipix, FNF acid) is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides.
S2089	Fenoldopam	Fenoldopam (SKF 82526) is a selective dopamine-1 (DA1) receptor agonist with natriuretic/diuretic properties with EC50 of 55.5 nM in stimulating cAMP accumulation in LLC-PK1 cells, which is more potent than DA .
S4618	Fenoldopam mesylate	Fenoldopam (SKF 82526, Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
S1823	Fenoprofen Calcium	Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.
S3027	Fenoprofen calcium hydrate	Fenoprofen calcium hydrate(Fenoprofen calcium salt dihydrate,Feprona dihydrate,Progesic dihydrate) is a non-steroidal anti-inflammatory drug (NSAID).
S5769	Fenoterol	Fenoterol (Phenoterol) is a β2 adrenoreceptor agonist with bronchodilator activity.
S5768	Fenoterol hydrobromide	Fenoterol hydrobromide (Phenoterol) is the the hydrobromide salt of fenoterol, a β2 adrenoreceptor agonist with bronchodilator activity.
S5233	Fenretinide	Fenretinide is a synthetic derivative of retinoic acid that has a broad-spectrum of cytotoxic activity against primary tumor cells, cell lines, and/or xenografts of various cancers (including neuroblastoma). Fenretinide (4-hydroxy(phenyl)retinamide; 4-HPR) is a synthetic derivative of retinoic acid, fenretinide can bind to retinoic acid receptor (RAR) and retinoid X receptor (RXR) at concentrations necessary to induce cell death.
S4090	Fenspiride HCl	Fenspiride(Decaspiride) is a bronchodilator with anti-inflammatory properties, inhibiting phosphodiesterase 4 and phosphodiesterase 3 activities with logIC50 values of 4.16 and 3.44, respectively, in human isolated bronchi.
S2031	Fenticonazole Nitrate	Fenticonazole Nitrate(Lomexin,REC 15-1476,Falvin) is an azole antifungal agent.
E3297	Fenugreek Seed Extract	Fenugreek Seed Extract is extracted from the seeds of Trigonella foenum-graecum, which acts as an antibacterial and anticancer agent.
S7243	Fer-1 (Ferrostatin-1)	Fer-1 (Ferrostatin-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.
E3166	Fermented Blank Bean Extract	Fermented Blank Bean Extract is extracted from the fermented Phaseolus vulgaris L., and aids in protection of the human digestive tract, mainly the colon.
E3137	Fermented Soybean Extract	Fermented Soybean Extract is obtained from Fermented soybean, which shows high antioxidant activity.
L6400	Ferroptosis Compound Library	A unique collection of 729 compounds used for exploring the mechanism of ferroptosis which is an iron-dependent form of non-apoptotic cell death.
S6449	Ferrous Bisglycinate	Ferrous bisglycinate (Iron glycinate) is a chelate that is used as a source of dietary iron. It acts as both a chelate and a nutritionally functional.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
S6406	Ferrous fumarate	Ferrous fumarate (Iron(II)) is the fumarate salt form of the mineral iron and is used in treatment of iron deficiency anemia.
S9221	Ferulaldehyde	Ferulaldehyde (Coniferaldehyde, Ferulyl aldehyde) is a natural intermediate of polyphenol metabolism of intestinal microflora.
S2300	Ferulic Acid	Ferulic Acid (Fumalic) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong. Ferulic acid is a novel fibroblast growth factor receptor (FGFR) inhibitor with IC50s of 3.78 μM and 12.5 μM for FGFR1 and FGFR2, respectively.
S5451	Ferulic acid methyl ester	Ferulic acid methyl ester (Methyl Ferulate, Methyl 4'-hydroxy-3'-methoxycinnamate) is a lipophilic derivative of ferulic acid, which is a hydroxycinnamic acid that is abundant in plants. It shows the strongest antioxidant activity and can protect against inflammation and cancer.
E3766	Feverfew Extract	Feverfew Extract is obtained from Tanacetum parthenium L., which is a herbal remedy used for preventing attacks of migraine.
S6413	fexaramine	Fexaramine is a potent, selective farnesoid X receptor (FXR) agonist with an EC50 of 25 nM and it displays no activity at hRXRα, hPPARα, hPPARγ, hPPARδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ and hVDR receptors.
S2600	Fexinidazole	Fexinidazole (HOE-239, Fexinidazole Winthrop) is a 5-nitroimidazole derivative. Fexinidazole is a DNA synthesis inhibitor and the only, all-oral agent for Human African Trypanosomiasis(HAT or sleeping sickness).
S3208	Fexofenadine HCl	Fexofenadine (MDL 16455A) inhibits histamine H1 receptor with IC50 of 246 nM.
E0109	Fezolinetant	Fezolinetant (ESN-364) is a potential antagonist of the neurokinin 3 receptor (NK3R). It interrupts pulsatile lh secretion and moderates levels of ovarian hormones throughout the menstrual cycle.
S8899	FF-10101	FF-10101 is a novel irreversible FLT3 inhibitor with ic50 of 0.20 nM and 0.16 nM for FLT3 (WT) and FLT3(D835Y), respectively.
S7979	FG-2216	FG-2216 is a potent, and orally active HIF prolyl 4-hydroxylase inhibitor with IC50 of 3.9 μM for PHD2. Phase 2.
E0621	FGFR1/DDR2 inhibitor 1	FGFR1/DDR2 inhibitor 1 is an inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoidin domain receptor 2 (DDR2).
S7450	FH1	FH1 is a small molecule, which promotes differentiation of iPS-derived hepatocytes.
E1178	FHD-286	FHD-286 is a BRG1/BRM ATPase inhibitor for the treatment of BAF-related disorders such as acute myeloid leukemia.
E1711	FHT-1015	FHT-1015 is a potent, small-molecule, allosteric inhibitor of SMARCA4/SMARCA2 ATPase with IC50 values ≤10 nM. FHT-1205 decreases PD1+TIM3+ cells and cytokine expression in vivo.
E1709	Fialuridine	Fialuridine(FIAU, DRG-0098, NSC 678514) is a nucleoside analog with antiviral activity. It blocks DNAsynthesis in human cytomegalovirus and hepatitis B, as well as herpes simplex.
A2661	Ficlatuzumab (Anti-HGF / SF)	Ficlatuzumab (Anti-HGF / SF) is a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF). It inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion and can be used to treat head and neck squamous cell carcinoma (HNSCC). MW :150 KD.
E4035	Ficoll(R) 400	Ficoll(R) 400 (sucrose-epichlorohydrin copolymer) is a macromolecular crowder that plays a pivotal role in promoting liquid-liquid phase separation (LLPS) of proteins. It is currently utilized in the isolation of serum and peripheral blood mononuclear cells (PBMC) from the whole blood of Parkinson's disease (PD) patients.
E3724	Ficus carica Extract	Ficus Carica Extract is obtained from Ficus carica Linn. (Moraceae), which has been used in traditional medicine for a wide range of ailments related to digestive, endocrine, reproductive, and respiratory systems.
E3735	Ficus hirta Vahl Extract	Ficus Hirta Vahl Extract is derived from Ficus hirta Vahl. (Wuzhimaotao), which possesses hepatoprotective, antibacterial, and anti-inflammatory bioactivities and improves memory function of AD mice.
S9682	FICZ	FICZ (6-Formylindolo[3,2-b]carbazole) is a potent agonist of aryl hydrocarbon receptor (AhR) that is efficiently metabolized by AHR-regulated cytochrome P4501 enzymes.
E0081	FIDAS-3	FIDAS-3 effectively competes against S-adenosylmethionine (SAM) for methionine sadenosyltransferase 2A (MAT2A) binding . FIDAS-3 has anticancer activities by inhibiting the expression of oncogenes. FIDAS-3 is a stilbene derivative and is a potent Wnt inhibitor with an IC50 of 4.9 μM for MAT2A.
S4227	Fidaxomicin	Fidaxomicin is a narrow spectrum macrocyclic antibiotic that inhibits RNA polymerase sigma subunit.
S7715	FIIN-3	FIIN-3 is an irreversible inhibitor of FGFR with an IC50 of 13.1, 21, 31.4, and 35.3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
S7354	Filanesib hydrochloride	Filanesib (ARRY-520) hydrochloride is a kinesin spindle protein (KSP) inhibitor that blocks the separation of centrosomes and assembly of spindles in the early stage of cell mitosis, and cell proliferation.
S0843	Filastatin	Filastatin, a long-lasting inhibitor of Candida albicans filamentation, inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay.
S7605	Filgotinib (GLPG0634)	Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.
S4975	Fimasartan	Fimasartan (Kanarb) is a non-peptide angiotensin II receptor antagonist (ARB) with noncompetitive, insurmountable binding with the AT1 receptor. It is used for the treatment of hypertension and heart failure.
S2759	Fimepinostat (CUDC-907)	CUDC-907 is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10 with IC50 of 19 nM and 1.7 nM/5 nM/1.8 nM/2.8 nM, respectively. CUDC-907 induces cell cycle arrest and apoptosis in breast cancer cells. Phase 1.
S1197	Finasteride	Finasteride (MK-906) is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with K_i of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).
E3366	Fineleaf Schizonepeta Herb Extract	Fineleaf Schizonepeta Herb Extract is extracted from the leaves of Schizonepeta, which is used as a traditional medicine with antipyretic, anti-inflammatory, analgesic, and hemostatic effects.
S9702	Finerenone	Finerenone (FIN, BAY 94-8862) is a highly selective and orally available nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM. Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.
S5950	Fingolimod (FTY-720)	Fingolimod (FTY-720) is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis.
S5002	Fingolimod (FTY720) HCl	Fingolimod (FTY720, Fingolimod Hydrochloride) HCl is a S1P antagonist with IC50 of 0.033 nM in K562, and NK cells. Please use saline solution rather than PBS for dilutions. PBS may cause precipitation.
E1244	FINO2	FINO2 is a potent ferroptosis inducer which inhibits GPX4 activity. FINO2 causes widespread lipid peroxidation.
S6478	Fipexide hydrochloride	Fipexide (hydrochloride) is a psychoactive drug of the piperazine class.
S7321	FIPI	FIPI (5-Fluoro-2-indolyl deschlorohalopemide), a derivative of halopemide, is a potent and selective inhibitor of phospholipase D with IC50 of 25 nM and 20 nM for PLD1 and PLD2, respectively.
E0500	Firocoxib (ML 1785713)	Firocoxib (ML 1785713) is a cyclooxygenase (COX)-2 inhibitor and a nonsteroidal anti-inflammatory drug. In vitro firocoxib inhibits COX-1 and COX-2 with an IC50 of 7.5 mM and 0.13 mM respectively in feline blood.
S8893	Firsocostat (GS-0976, ND-630)	Firsocostat (GS-0976, ND-630) is a reversible inhibitor of acetyl CoA carboxylase (ACC) with IC50s of 2.1 nM,6.1 nM for hACC1 and hACC2,respectively.
S8503	Fisogatinib (BLU-554)	Fisogatinib (BLU-554) is a potent, highly-selective, oral FGFR4 inhibitor with an IC50 value of 5 nM. The IC50s for FGFR1-3 is 624-2203 nM.
E2695	FITC-Dextran (MW 10000)	FITC-Dextran(MW 10000) are polysaccharides comprised of varying lengths of branched glucose molecules and can be used to determine solute, ion and protein permeability of the blood-brain barrier (BBB) based on the size of the dextran used.
S2595	FK-3311	FK-3311 (COX-2 Inhibitor V) is a selective, cell-permeable and orally available inhibitor of cyclooxygenase-2 (COX-2) with antiinflammatory. FK-3311 has protective effects against hepatic warm ischemia-reperfusion injury by marked inhibition of TxA2.
S0535	FK962	FK962, a derivative of FK960 with putative anti-dementia properties, significantly enhances high K+-evoked somatostatin release from rat hippocampal slices at 1-1000 nM, also significantly reduces somatostatin-induced inhibition of Ca2+ channels at 1-100 nM in single rat hippocampal neurons.
S1027	FL-411	FL-411 (BRD4-IN-1) is a potent and selective inhibitor of Bromodomain-containing protein 4 (BRD4) with IC50 of 0.43 μM for BRD4(1). FL-411 induces ATG5-dependent autophagy-associated cell death (ACD) by blocking BRD4-AMPK interaction.
E1713	FL118	FL118(10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin analog, is a potent and orally active inhibitor of Survivin. FL118 also selectively and independently inhibits three additional cancer-associated survival genes Mcl-1, XIAP, and cIAP2 in a p53 status-independent manner. FL118 displays potent antitumor activity and can be used in cancer research.
E3094	Flatstem Milkvetch Seed Extract	Flatstem Milkvetch Seed Extract is obtained from the dried ripe seed of Flatstem Milkvetch, benefits the liver and the kidney, arrests seminal discharge, restrains urination and improves eyesight.
S3679	Flavanone	Flavanones (2,3-Dihydroflavone, 4-Flavanone, 2-Phenyl-4-chromanone, 2-Phenylchroman-4-one) show strong antioxidant and radical scavenging activity, and appear to be associated with a reduced risk of certain chronic diseases, the prevention of some cardiovascular disorders, and certain kinds of cancer. Flavanones also exhibit antiviral, antimicrobial, and anti-inflammatory activities, beneficial effects on capillary fragility, and an ability to inhibit human platelet aggregation, anti-ulcer, and anti-allergenic properties.
E0705	Flavin Adenine Dinucleotide Disodium	Flavin Adenine Dinucleotide Disodium is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
S5600	Flavokawain A	Flavokawain A, extracted from kava, is an apoptotic inducers and anticarcinogenic agent. Flavokawain A can down-regulation of antiapoptotic proteins, such as XIAP, survivin, and Bcl-xL, thereby changing the balance between apoptotic and antiapoptotic molecules and then induce cell death in tumor cells.
S3967	Flavone	Flavone (2-Phenylchromone, 2-Phenyl-4-chromone, 2-Phenyl-4-benzopyron), a class of flavonoids, mainly found in spices and red or purple plant foods with antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular disease, neurodegenerative disorders etc.
L7700	Flavonoid Compound Library	A unique collection of 260 flavonoid compounds used for high throughput screening(HTS) and high content screening(HCS).
S1230	Flavopiridol (Alvocidib)	Flavopiridol (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4, CDK6, and CDK9 with IC50 values in the 20-100 nM range. It is more selective for CDK1, 2, 4, 6, 9 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol induces autophagy and ER stress. Flavopiridol blocks HIV-1 replication. Phase 1/2.
S2679	Flavopiridol (Alvocidib) HCl	Flavopiridol (Alvocidib) HCl competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM in cell-free assays. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol HCl induces autophagy and ER stress. Flavopiridol HCl blocks HIV-1 replication. Phase 1/2.
S4027	Flavoxate HCl	Flavoxate (NSC-114649) is a muscarinic AChR antagonist with IC50 of 12.2 μM.
E3796	Flaxseed Extract	Flaxseed Extract is drawed from Linum usitatissimum, which can regulate the growth of MCF-7 cells and induce apoptosis.
E0528	Flecainide	Flecainide is a common medication used to help restore and maintain sinus rhythm in patients with atrial fibrillation.
S2469	Fleroxacin	Fleroxacin (Ro 23-6240,AM-833,Quinodis, Megalocin) is a new broad-spectrum fluoroquinolone.
S7399	FLI-06	FLI-06 is a novel inhibitor of Notch signaling with EC50 of 2.3 μM.
S3716	Flibanserin	Flibanserin (BIMT-17, BIMT-17-BS) is a nonhormonal, centrally acting molecule that acts as an agonist at postsynaptic 5-HT1A receptors and as an antagonist at 5-HT2A receptors.
S7259	FLLL32	FLLL32 is a potent JAK2/STAT3 inhibitor with IC50 of <5 μM. FLLL32 inhibits the induction of STAT3 phosphorylation by IFNα and IL-6 in breast cancer cells.
S4249	Flopropione	Flopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist.
S4201	Florfenicol	Florfenicol (SCH-25298,(-)-Florfenicol) is a fluorinated synthetic analog of thiamphenicol with broad-spectrum, primarily bacteriostatic activity.
E3787	Flos Inulae Extract	Flos Inulae Extract is drawed from Flos Inulae, which can be applied to antimutation, antityrosinase and anti-inflammation.
S1299	Floxuridine (FUDR)	Floxuridine (FUDR) is a prodrug that is rapidly catabolized to 5-fluorouracil in vivo. Floxuridine is used to treat various cancers, particularly metastases to the liver. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage and apoptosis. Floxuridine has antiviral effects against HSV and CMV.
E2387	FLT3-IN-2	FLT3-IN-2 is a FLT3 inhibitor with IC50 of ＜ 1 μM.
S1837	Flubendazole	Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.
S4850	Flucloxacillin sodium	Flucloxacillin sodium (Floxacillin sodium) is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.
S1331	Fluconazole	Fluconazole is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections.
S1666	Flucytosine (5-Fluorocytosine)	Flucytosine (5-Fluorocytosine) is an antifungal drug with IC50 of 0.93 μM in C. albicans.
S1491	Fludarabine	Fludarabine is a STAT1 activation inhibitor which causes a specific depletion of STAT1 protein (and mRNA) but not of other STATs. Also a DNA synthesis inhibitor in vascular smooth muscle cells. Fludarabine induces apoptosis.
S1229	Fludarabine Phosphate	Fludarabine Phosphate is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.
S3659	Fludrocortisone acetate	Fludrocortisone (9α-fluorocortisol) is a synthetic pregnane steroid and a halogenated derivative of cortisol. It is used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency.
S4268	Flufenamic acid	Flufenamic Acid is an anti-inflammatory agent, and also acts as an ion channel modulator.
E0514	Flugestone 17-acetate	Flugestone 17-acetate (Flurogestone acetate) is a corticosteroid hormone.
S9973	Flumatinib (HH-GV-678)	Flumatinib (HH-GV-678) is a novel inhibitor of Bcr-Abl with IC50 values of 1.2 nM, 307.6 nM and 665.5 nM for c-Abl, PDGFRβand c-Kit, respectively.
S1332	Flumazenil	Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.
S3181	Flumequine	Flumequine(R-802) is a synthetic chemotherapeutic antibiotic, inhibiting topoisomerase II with IC50 of 15 μM.
S4088	Flumethasone	Flumethasone (RS-2177, NSC-54702,Flumetasone) is a glucocorticoid receptor agonist, this complex binds to the nucleus causing a variety of genetic activation and repressions.
S2030	Flunarizine 2HCl	Flunarizine 2HCl (KW-3149, R14950) is a dihydrochloride salt form which is a calcium channel blocker with a K_i of 68 nM.
S2108	Flunixin Meglumin	Flunixin Meglumin(Banamine) is a potent inhibitor of the enzyme cyclooxygenase (COX) used as analgesic agent with anti-inflammatory and antipyretic activity.
S2470	Fluocinolone Acetonide	Fluocinolone Acetonide (Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor.
S2608	Fluocinonide	Fluocinonide (Vanos,nsc 101791) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.
S5488	Fluorescein	Fluorescein (Solvent Yellow 94, Resorcinolphthalein, Yellow fluorescein) is a manufactured organic compound and dye.
S6928	Fluorescein-5-isothiocyanate (FITC)	Fluorescein-5-isothiocyanate (FITC, Fluorescein isothiocyanate isomer I, 5-FITC) is a fluorescent probe capable of being conjugated to tissue and proteins.
E4034	Fluorescent Brightener 28	Fluorescent Brightener 28 (Tinopal UNPA-GX) is a viability stain used for identification of structure chitin and fungi. It is also used as a fluorescent brightening agent for cellulose and polyamide fabrics, paper and in detergents and soaps.
E1620	Fluorofurimazine	Fluorofurimazine is a novel furimazine analogue, with increased aqueous solubility enabling higher signal emission than furimazine for bioluminescence imaging. Fluorofurimazine enables higher substrate loading and improved optical imaging sensitivity in in-vivo.
S5486	Fluorometholone	Fluorometholone (Oxylone) is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye.
S4228	Fluorometholone Acetate	Fluorometholone Acetate (NSC 47438,Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.
S5421	Fluoroquinolonic Acid	Fluoroquinolonic Acid (Ciprofloxacin Impurity A, Q-Acid) is an antibiotic and antimicrobial agent.
S1333	Fluoxetine HCl	Fluoxetine HCl is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.
S4569	Fluphenazine dihydrochloride	Fluphenazine dihydrochloride (Prolixin) is a phenothiazine-class D1DR and D2DR inhibitor. It also inhibits Histamine H1 Receptor.
S1334	Flupirtine maleate	Flupirtine maleate is the salt form of Flupirtine, which is a centrally acting non-opioid analgesia, is a selective neuronal potassium channel opener that also has NMDA receptor antagonist properties.
S6470	Fluralaner	Fluralaner (A1443, AH252723) is a systemic insecticide and acaricide that is administered orally.Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABAA receptors) and L-glutamate-gated chloride channels (GluCls)
S1679	Flurbiprofen	Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs).
S6457	Flurbiprofen Axetil	Flurbiprofen Axetil is one of the commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) that nonselectively inhibits cyclooxygenase.
E1410	Fluspirilene	Fluspirilene(R 6218; Redeptin) is a non-competitive antagonist of L-type calcium channels with an IC50 of 0.03 μM in cell-free assays. Fluspirileneis a long-acting injectable depot antipsychotic agent used for schizophrenia.
S1908	Flutamide	Flutamide (SCH-13521) is an antiandrogen drug, with its active metablolite binding at androgen receptor with K_i values of 55 nM, and primarily used to treat prostate cancer.
S6487	fluticasone furoate	Fluticasone furoate (GW685698) is an inhaled corticosteroid/long-acting beta-agonist combination with a prolonged bronchodilator duration of action. It is used for the treatment of non-allergic and allergic rhinitis administered by a nasal spray.
S1992	Fluticasone propionate	Fluticasone Propionate (CCI-187881) is a synthetic glucocorticoid, used to treat non-allergic and allergic rhinitis.
S1909	Fluvastatin Sodium	Fluvastatin Sodium inhibits HMG-CoA reductase activity with IC50 of 8 nM in a cell-free assay.
S1336	Fluvoxamine (DU-23000) maleate	Fluvoxamine maleate (DU-23000, MK-264) is a selective serotonin (5-HT) reuptake inhibitor (SSRI), used in the treatment of obsessive-compulsive disorder.
S9712	Fluzoparib (SHR-3162)	Fluzoparib (SHR3162, HS10160) is a potent Poly (ADP-ribose) polymerase (PARP) inhibitor that shows anti-tumor activity, with an IC50 of 1.46±0.72 nM for PARP1.
S8541	FM-381	FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively.
E1712	FM19G11	FM19G11 is a hypoxia-inducible factor-1-alpha (HIF-1α) inhibitor, and it inhibits hypoxia-induced luciferase activity with an IC50 of 80 nM in HeLa cells.
S0091	Fmoc-Val-Ala-PAB	Fmoc-Val-Ala-PAB (Fmoc-Val-Ala-PAB-OH) is a useful and cleavalbe linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery.
S6688	Fmoc-Val-Cit-PAB	Fmoc-Val-Cit-PAB (Fmoc-Val-Cit-PAB-OH) is a cleavable linker for antibody-drug conjugates (ADC).
E2658	FN-1501	FN-1501 is a potent inhibitor of Fms-like receptor tyrosine kinase 3 (FLT3) and cyclin-dependent kinase (CDK), with IC50s of 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively.
E3768	Foeniculum Vulgare Extract	Foeniculum Vulgare Extract is obtained from Foeniculum vulgare (Apiaceae), which is traditionally suggested for the fertility improvement in Iranian lore due to its antioxidant and phytoestrogen compounds.
S4605	Folic acid	Folic acid (Folacin, Vitamin B9, Vitamin M, Pteroylglutamic acid, Folate), a B vitamin, plays an important role in cell division and in the synthesis of amino acids and nucleic acids like DNA.
S5790	Folinic acid (Leucovorin)	Folinic acid (Leucovorin) is a biological folic acid that increases the level of reduced folates in tissues, which promotes the inhibition of thymidylate synthase (TS).Solutions are unstable and should be fresh-prepared.
S1717	Fomepizole	Fomepizole (4-methylpyrazole, Antizol, Antizol-Vet) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
S3736	Fondaparinux Sodium (Org 31540)	Fondaparinux Sodium (Org 31540, Natural heparin pentasaccharide, Fondaparin, SR-90107A) is a synthetic glucopyranoside with antithrombotic activity. It selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin; a synthetic inhibitor of Factor Xa.
S6159	Food Yellow 3	Food Yellow 3 (Sunset yellow) is an azo dye that is useful in fermented foods which must be heat treated.
S5306	Forchlorfenuron (CPPU)	Forchlorfenuron (CPPU) is a synthetic cytokinin that inhibits septins and exhibits anti-parasitic, anticancer, and anti-angiogenic activities.
S1111	Foretinib	Foretinib is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met (c-Met) and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit (c-Kit), PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
E2922	Formamide	Formamide (Methanamide; Formimidic acid) is a clear liquid amide derived from formic acid. It allows for the denaturation and renaturation of nucleic acids at room temperature. Formamide-induced DNA denaturation when combined with detection of denatured DNA with a monoclonal antibody (MAb) makes it possible to specifically identify the apoptotic cells.
E2995	Formamide deionized	Formamide deionized(Methanamide, Formimidic acid) is a clear liquid amide derived from formic acid that serves as an essential solvent for catalytic hydrogenation reactions and acts as a reagent in the creation of diverse organometallic compounds.
S5382	Formate	Formate is the anion derived from formic acid, an important intermediate in chemical synthesis and occurs naturally, most notably in some ants.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S2208	Formestane	Formestane (CGP-32349, NSC 282175) is a second generation selective aromatase inhibitor with an IC50 of 80 nM.
S2299	Formononetin	Formononetin (Formononetol, Biochanin B) is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone.
S2020	Formoterol Hemifumarate	Formoterol Hemifumarate (Eformoterol, CGP 25827A, NSC 299587, YM 08316,Formoterol fumarate) is a potent, selective and long-acting β2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD).
S2449	Forskolin (Colforsin)	Forskolin (Colforsin) is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types, commonly used to raise levels of cAMP in the study and research of cell physiology. Forskolin also activates PXR and FXR activity. Forskolin stimulates autophagy.
E3415	Forsythia suspensa Extract	Forsythia suspensa Extract is extracted from Forsythia suspensa.
S3926	Forsythin	Forsythin (FOR, Phillyrin) is an active ingredient extracted from the fruit of the medicinal plant Forsythia suspensa (Thunb.) Vahl and has been shown to have antioxidant, antibacterial and antiinflammatory properties.
S9184	Forsythoside B	Forsythoside B is a phenylethanoid glycoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant. Forsythoside B has potent neuroprotective effects and has anti-inflammation, antioxidant, and antisepsis properties. Forsythoside B could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB.
S6581	Fosamprenavir calcium salt	Fosamprenavir(GW433908G) is a pro-drug of the protease inhibitor and antiretroviral drug amprenavir. It is used for the treatment of HIV-1 infections.
S3038	Fosaprepitant dimeglumine salt	Fosaprepitant dimeglumine salt (MK-0517) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.
S7204	Fosbretabulin (Combretastatin A4 Phosphate) Disodium	Fosbretabulin (Combretastatin A4 Phosphate) Disodium is the water-soluble prodrug of Combretastatin A4 (CA4), which is a microtubule-targeting agent that binds β-tubulin with K_d of 0.4 μM in a cell-free assay. Fosbretabulin Disodium inhibits the polymerization of tubulin with IC50 of 2.4 μM, and also disrupts tumor vasculature. Fosbretabulin disodium induces mitotic arrest and apoptosis in endothelial cells. Phase 3.
S3076	Foscarnet Sodium	Foscarnet Sodium (Phosphonoformate) inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs.
E0465	Fosciclopirox	Fosciclopirox(CPX-POM) selectively delivers the active metabolite, Ciclopirox (CPX) that targets γ-secretase complex (Presenilin 1 and Nicastrin)2. It is used in the treatment of urothelial cancer and a number of solid and hematologic malignancies.
S6467	Fosfluconazole	Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
S3710	Fosfomycin calcium	Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
S5048	Fosfomycin Disodium	Fosfomycin (Phosphonemycin) is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis.
S5729	Fosfosal	Fosfosal (2-phosphonoxy benzoic acid) is a non-acetylated salicylic acid derivative, with analgesic and anti-inflammatory activity, but without effects on PG biosynthesis in vitro.
S2095	Fosinopril Sodium	Fosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.
S6482	Fosphenytoin (disodium)	Fosphenytoin (disodium) is the sodium salt form of fosphenytoin, a prodrug that is hydrolyzed to the anticonvulsant phenytoin upon parental administration.
S2625	Fostamatinib (R788)	Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.
S2206	Fostamatinib (R788) disodium	Fostamatinib disodium (R788, Tamatinib Fosdium), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.
S4944	Fostamatinib disodium hexahydrate	Fostamatinib (R788) disodium (Tamatinib Fosdium) hexahydrate, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay.
S7220	Fostemsavir	Fostemsavir (BMS-663068, Rukobia), the phosphonooxymethyl prodrug of BMS626529, is an attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells with EC50 of < 10 nM.
S6961	Foxy-5	Foxy-5, a Wnt-5a mimicking hexapeptide, is a WNT signalling pathway modulator potentially for the treatment of metastatic breast cancer, prostate cancer and colorectal cancer.
S3511	FOY251	FOY251, an active metabolite of camostat mesilate, is an inhibitor of synthetic serine protease. FOY251 inhibits SARS-CoV-2 infection.
S7451	FPH1	FPH1 is a small molecule, which promotes expansion of iPS-derived hepatocytes.
S7452	FPH2 (BRD-9424)	FPH2 (BRD-9424) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.
S0759	FPL 62064	FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and prostaglandin synthetase (cyclooxygenase, COX) with IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and seminal vesicle prostaglandin synthetase, respectively. FPL 62064 has potent anti-inflammatory activity.
S8185	FPS-ZM1	FPS-ZM1 is a blood-brain-barrier permeant, non-toxic, tertiary amide compound which is a high affinity RAGE-specific inhibitor, blocking Aβ binding to the V domain of RAGE.
E1275	FR054	FR054 is a novel inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3 with a remarkable anti-breast cancer effect.
L1600	Fragment Library	A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD).
E0511	Framycetin sulphate	Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM, and competes for specific divalent metal ion binding sites in RNase P RNA, also inhibits hammerhead ribozyme with a Ki of 13.5 μM.
S9503	Fraxetin	Fraxetin (7,8-dihydroxy-6-methoxy coumarin), found in Fraxinus rhynchophylla, shows potent antioxidant activity.fraxetin alleviates lipid peroxidation, enhances hepatic antioxidant capabilities, inhibits CYP2E1 activity, and reduced the inflammatory mediators, including TNF-α and IL-1β via up-regulation of hemeoxygenase-1 (HO-1) protein.
S9296	Fraxin	Fraxin (Fraxetin-8-O-glucoside), a main active component isolated from Cortex Fraxini, possesses a variety of bioactivities such as anti-inflammatory, antioxidant, analgesic, antimicrobial, antiviral, immunomodulatory, anti-hyperuricemia and diuresis.
S2418	Frentizole	Frentizole (Frentizol) is a novel inhibitor of amyloid beta peptide (Abeta) binding alcohol dehydrogenase (ABAD) interaction with IC50 of 200 μM. Frentizole is a nontoxic antiviral and immunosuppressive agent used clinically in rheumatoid arthritis and systemic lupus erythematosus.
E3578	Fringed pink Extract	Fringed Pink Extract is extracted from Dianthus superbus, which has anti-inflammatory activity.
E3099	Fritillaria Cirrhosa Seed Extract	Fritillaria Cirrhosa Seed Extract is extracted from the seeds of Fritillaria Cirrhosa, which is famous for its antitussive, expectorant, anti-asthma and anti-inflammatory properties, and is widely used to treat respiratory diseases.
E3098	Fritillariae Cirrhosae Bulbus Extract	Fritillariae Cirrhosae Bulbus Extract is obtained from Fritillariae cirrhosae, mediates apoptosis through a STAT1 and STAT4-mediated co-regulatory network, which may be the key novel mechanism for its antitumor activity.
E3867	Fritillariae Thunbergii Bulbus Extract	Fritillariae Thunbergii Bulbus Extract is extracted from Fritillariae thunbergii bulbus, which is used to treat symptoms of cough and airway congestion in the chest due to pathological colds and damp phlegm.
S5848	Frovatriptan Succinate	Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
S5176	Fructose	Fructose (D-(-)-Fructose, Fruit sugar, levulose, fructosteril, D-fructofuranose, D-arabino-hexulose) is a simple ketonic monosaccharide found in many plants.
E3847	Fructus Akebiae Extract	Fructus Akebiae Extract is extracted from Fructus akebiae, which is used for the treatment of mental disorders.
E3006	Fructus Anisi Stellati Extract	Fructus Anisi Stellati Extract is extracted from the fruit of Illicium verum, which involves in signalling pathways that target cancer cell apoptosis, proliferation, and tumour metastasis in Gastric cancer cells.
E3474	Fructus Chebulae Extract	Fructus Chebulae Extract is extracted from the mature fruit of Terminalia chebula Retz., which can rescue neuronal cell death against ischemia-related damage.
E3721	Fructus mume Extract	Fructus mume Extract is obtained from the processed fruit of Fructus mume Sieb. et Zucc., which effectively improves cognitive impairment in familial Alzheimer's disease, scopolamine-induced memory impairment, and chronic cerebral hypoperfusion-induced cognitive impairment.
E3393	Fructus azedarach Extract	Fructus azedarach Extract is extracted from Fructus azedarach.
S5667	Fruquintinib	Fruquintinib is a small molecule inhibitor with strong potency and high selectivity against VEGFR family. It inhibits VEGFR 1, 2, 3, with IC50 values of 33 nM, 35 nM and 0.5 nM, respectively and shows only weak inhibition of RET, FGFR-1 and c-kit kinases.
E1574	FSEN1	FSEN1 is a potent and non-competitive FSP1 inhibitor with an IC50 value of 313 nM. It triggers iron death in cancer cells by inhibiting FSP1 and can be used in research of cancer.
S8428	FSL-1	FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection.
S9915	FSLLRY-NH2 TFA	FSLLRY-NH2 TFA (FSY-NH2) is a selective protease-activated receptor 2 (PAR2) inhibitor with an ic50 of 50 µM in PAR2-KNRK cells.
S6666	FT113	FT113 is a potent inhibitor of fatty acid synthase (FAS/FASN) with ic50 of 213 nM.
S6464	Ftaxilide	Ftaxilide is a novel antituberculosis agent.
S7465	FTI 277 HCl	FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.
E0365	Fucoidan	Fucoidan is an anionic sulfated polysaccharide extracted from marine brown algae with a large range of biological activities, including anti-inflammatory, anti-cancer, anti-viral, anti-oxidation, anticoagulant, antithrombotic, anti-angiogenic and anti-Helicobacter pylori, etc.
E3488	Fucus vesiculosis Extract	Fucus Vesiculosis Extract is extrcated from Fucus vesiculosus, which has antifungal properties.
S2129	Fudosteine	Fudosteine is a cysteine derivative and a MUC5AC mucin hypersecretion inhibitor, used as a muco-active agent with indications for chronic respiratory diseases.
S0042	Fulacimstat	Fulacimstat (BAY1142524) is an orally available inhibitor of chymase with IC50 of 4 nM and 3 nM for human and hamster chymase enzyme, respectively.
S1191	Fulvestrant	Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM in a cell-free assay. Fulvestrant also induces autophagy and apoptosis and has antitumor activity.
S7784	Fumagillin	Fumagillin(Amebacilin,NSC9168) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
S4952	Fumaric acid	Fumaric acid (Fumarate, 2-Butenedioic acid, Trans-Butenedioic acid) is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate (ATP) from food; also a product of the urea cycle.
S3709	Furagin	Furagin (NF-416, F-35, Akritoin, Furazidin, Furazidine) is 2-substituted 5-nitrofuran, chemically and structurally similar to well-known antibacterial compound nitrofurantoin with antimicrobial activities.
S4203	Furaltadone HCl	Furaltadone HCl(Altafur hydrochloride) is an antibacterial and has distinct curative effect in the treatment of coccidiosis.
S4528	Furazolidone	Furazolidone(Furoxone) is a synthetic nitrofuran derivative with bactericidal or bacteriostatic activity when used against Gram-positive and Gram-negative bacteria.
S6211	Furfural	Furfural is one of the key chemicals produced in the so-called lignocellulosic biorefineries and produced from renewable agricultural sources such as food crop residues and wood wastes.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S5831	Furfuryl acetate	Furfuryl acetate (Furan-2-ylmethyl, 2-Furanmethanol, 2-Acetoxymethylfuran) is widely used as a flavoring agent in food and bakery.
S1603	Furosemide	Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used in the treatment of congestive heart failure and edema.
S5194	Furosemide sodium	Furosemide (Frusemide) sodium is a potent and orally active inhibitor of Na-K-Cl cotransporter (NKCC). Furosemide sodium is a subtype-selective antagonist of gamma-aminobutyric acid type A (GABAA) receptor.
S6614	Fursultiamine	Fursultiamine (Thiamine tetrahydrofurfuryl disulfide) is a nutritional supplement and vitamin B1 derivative, with potential antineoplastic activity.
S4663	Fusidate Sodium	Fusidate Sodium (Fucidin, SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.
S3971	Fusidine	Fusidine (Fusidic Acid), isolated from Fusidium coccineum, is a steroidal antibiotic that inhibits protein synthesis.
S8848	Futibatinib (TAS-120)	Futibatinib (TAS-120) is an irreversible fibroblast growth factor receptor (FGFR) inhibitor which inhibits all 4 subtypes of FGFR with enzyme IC50 values of 1.8 nM, 1.4 nM, 1.6 nM and 3.7 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
S8591	FX1	FX1 is a selective BCL6 BTB inhibitor with an IC50 value of 35 μM in reporter assays. FX1 shows great selectivity against a panel of 50 different kinases. 10 μM FX1 fails to significantly inhibit of any of these kinases. FX1 induces apoptosis.
S8928	FX11	FX-11(LDHA Inhibitor FX11) is a potent inhibitor of lactate dehydrogenase A (LDHA)) with IC50 of 49.27 μM in BxPc-3 cells.