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NF-κB Signaling Compound Library

Catalog No.L5500

A unique collection of 428 small molecules used for NF-κB signaling pathway research which plays a key role in immunology/inflammation and cancer.

96 well box

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NF-κB Signaling Compound Library Contents
Description & Advantages
• A unique collection of 428 small molecule compounds  for high throughput screening(HTS) and high content screening (HCS)
 
• A useful tool for NF-κB signaling pathway research
 
• For studying human diseases, exploring the pathogenesis of diseases such as cancer, and opening noval therapeutic ways
 
• Structurally diverse, medicinally active, and cell permeable
 
• Rich documentation with structure description, target information, IC50 values and customer reviews
 
• NMR and HPLC validated to ensure high purity

 

Product Details
Formulation 409 compounds pre-dissolved in 10mM DMSO, 11 compounds pre-dissolved in 10 mM Water and 8 compounds pre-dissolved in 2 mM DMSO
Container 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability 12 months -20°C in DMSO
24 months -80°C in DMSO
Shipping Blue ice or dry ice
Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

    Nature.2019;574(7777):268-272

  • Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

    Nat Commun. 2019 16;10(1):2197

  • Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

    Cell Res. 2019;29(9):739-753

  • Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

    Mov Disord. 2019;34(3):323-334

  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

    Blood. 2019 17;134(16):1323-1336

  • Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

    Cancer Immunol Res.2017;5(9):790-803

NF-κB Signaling Compound Library Composition
HTS Facility Partners