Screening Libraries
What is a Bioactive Screening Library?
The libraries consist of a unique and diverse collection of over 120,000 small molecules with validated biological and pharmacological activities Safety and effectiveness of the compounds has been demonstrated by preclinical and clinical research, and many of the compounds are FDA-approved. The collections of unique small molecules, which include inhibitors, activators, antagonists, and agonists, are focused on over 200 targets that are part of more than 20 signaling pathways . These pathways include, among many others, apoptosis, and the PI3K/Akt/mTOR, and MAPK pathways. Selleck offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution).
Compound Library Advantages
Structurally diverse, medicinally active, and cell permeable
Rich documentation with structure, IC50, and customer reviews
NMR and HPLC validated to ensure high purity
You can select compounds, quantities, format (dry/solid or DMSO) and plate map to meet your specific requirement.
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FDA-approved Drug Library
A unique collection of 2102 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS).
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Clinical Compound Library
A unique collection of 2570 clinical compounds for high throughput screening (HTS) and high content screening (HCS).
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Bioactive Compound Library-I
A unique collection of 5028 bioactive chemical compounds for high throughput screening (HTS) and high content screening (HCS).
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Bioactive Compound Library-Ⅱ (Provided by Pfizer)
A unique collection of 3000 bioactive chemical compounds for high throughput screening (HTS) and high content screening (HCS).
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Kinase Inhibitor Library
A unique collection of 760 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).
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Express-Pick Library (Provided by Pfizer)
A unique collection of 4208 chemical compounds featured different core structures and structural diversities respectively for high throughput screening (HTS) and high content screening (HCS).
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Natural Product Library
A unique collection of 1869 natural products for high throughput screening (HTS) and high content screening (HCS).
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Human Endogenous Metabolite Compound Library
279 small collections of human endogenous metabolites, involving multiple metabolic pathways, which can be used for high-throughput screening, opening up new ways for humans to treat various diseases such as tumors.
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Metabolism Compound Library
A unique collection of 903 small molecules with biological activity in numerous metabolic pathway: glycometabolism, lipid metabolism, proteolysis, etc.
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Target Selective Inhibitor Library
A unique collection of 318 validated bioactive compounds covering over 123 targets.
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Epigenetics Compound Library
Selleck Epigenetic inhibitor Library contains various small molecule modulators (inhibitors and activators) with biological activity used for epigenetic research and associated assays.
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Stem Cell Signaling Compound Library
Selleck Stem Cell Small Molecule Compound Library contains various small molecule inhibitors with biological activity used for stem cell regulatory and signaling pathway research.
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Inhibitor Library
A unique collection of 2707 inhibitors for high throughput screening (HTS) and high content screening (HCS).
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Apoptosis Compound Library
A unique collection of 691 small molecules used for apoptosis research targeting Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survivin, etc.
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FDA-approved Drug Library (Simplified Edition)
A unique collection of 1855 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS)
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GPCR Compound Library
Selleck GPCR Small Molecule Compound Library contains various small molecules targeting G protein coupled receptors with biological activity.
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Cambridge Cancer Compound Library
A unique collection of 247 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS).
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Immunology/Inflammation Compound Library
A unique collection of 1080 small molecules modulators (inhibitors and activators) with biological activity used for Immunology/Inflammation research and associated assays.
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Drug Repurposing Library
A unique collection of 2368 drugs that are marketed around the world or that have passed phase 1 clinical trials for high throughput screening (HTS) and high content screening (HCS).
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Pfizer Licensed Compound Library
Selleck and Pfizer are proud to present a unique collection of 81 drug compounds licensed by Pfizer.
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MAPK Inhibitor Library
A unique collection of 94 small molecule inhibitors used for MAPK signaling research.
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Fragment Library
A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD).
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Neuronal Signaling Compound Library
A unique collection of 1109 small molecule compounds with biological activity used for neurologic research and associated assays
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PI3K/Akt Inhibitor Library
A unique collection of 174 small molecule inhibitors used for PI3K/Akt/mTOR pathway research.
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Anti-diabetic Compound Library
A unique collection of 155 small molecules affecting the development of diabetes.
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Anti-infection Compound Library
A unique collection of 921 anti-infective small molecules with biological activity of antibiotics,antifungal drugs,anti-HIV,etc.
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Anti-cancer Compound Library
A unique collection of 1920 anti-cancer small molecules for 12 types of cancers: Breast Cancer, Leukemia, Lung Cancer, Lymphoma, etc.
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Tyrosine Kinase Inhibitor Library
Tyrosine Kinase Inhibitor library is ideal database for high-throughput screening (HTS) and cell based high-content screening (HCS).
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Ion Channel Ligand Library
A unique collection of 230 small molecule modulators used for Ion channel research.
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Protease Inhibitor Library
A unique collection of 228 small molecule inhibitors used for chemical genomics, high-throughput screening (HTS), and high content screening (HCS).
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Autophagy Compound Library
A unique collection of 215 small molecules with autophagy-inducing or autophagy-inhibiting activity.
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Bioactive Compound Library (Simplified Edition)
A unique collection of 4489 bioactive chemical compounds for high throughput screening (HTS) and high content screening (HCS)
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HTS Library for Drug Discovery (Provided by Pfizer)
A unique collection of 110000 innovative compounds features numerous structurally diverse compounds and several alternate compositions.
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DNA Damage/DNA Repair compound Library
A unique collection of 179 small molecules used for DNA Damage and Repair research targeting PARP,ATM/ATR,Topoisomerase,DNA/RNA Synthesis etc.
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CNS-Penetrant Compound Library
A unique collection of 307 CNS-Penetrant compounds with biological activity for neurologic research.
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Small Molecule Immuno-Oncology Compound Library
A unique collection of 38 Immuno-Oncology small molecules used for oncotherapy in conjunction with other medicines.
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Histone modification compound library
A unique collection of 114 small molecule compounds with biological activity used for epigenetic research and associated assays.
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Cell Cycle compound library
A unique collection of 122 small molecule compounds with biological activity used for tumor proliferation research and associated assays.
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Angiogenesis Related compound Library
A unique collection of 112 small molecules used for angiogenesis research targeting Bcr-Abl,BTK,HIF,VEGFR,FGFR,FAK, etc.Abnormal angiogenesis can lead to a variety of diseases, such as tumors, diabetes, immune diseases and so on. Therefore, angiogenesis has become a drug target for the treatment of these diseases.
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Antibiotics compound Library
A unique collection of 415 small molecules used for anti-infection research in order to identify drug target and open up new mechanism and ways to treat human disease.
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JAK/STAT compound library
A unique collection of 51 small molecules used for disease research targeting JAK,STAT,Pim, etc.JAK-STAT signaling pathway is involved in regulating biological
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NF-κB Signaling Compound Library
A unique collection of 41 small molecules used for NF-κB Signaling pathway research which plays a key role in inflammatory and immune responses.
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TGF-beta/Smad compound library
A unique collection of 29 small molecules with biological activity used for TGF-beta/Smad pathway research.
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