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Famciclovir Antiviral chemical

Name: Famciclovir
Brand: Selleck Chemicals
SKU: S2467
Availability: InStock
Rating: 5 (12 reviews)

Cat.No.S2467

Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.

Chemical Structure

Molecular Weight: 321.33863

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S246701 DMSO]64 mg/mL]false]Water]64 mg/mL]false]Ethanol]48 mg/mL]false Purity: 99.98%

99.98

Related Targets	Bacterial Antibiotics Anti-infection Fungal COVID-19 Parasite Reverse Transcriptase HIV HCV Protease SARS-CoV HIV Protease Influenza Virus β-lactamase Integrase HBV CMV Neuraminidase HCV HSV RSV Enterovirus Thioredoxin Reductase 3C-Like Protease Ribosomal Peptidyl Transferase HPV
Related Products	Moroxydine HCl Aloperine GS-441524 Oleanolic Acid NGI-1 Lapachol Saikosaponin B2 Harringtonine U18666A

Chemical Information, Storage & Stability

Molecular Weight	321.33863	Formula	C₁₄H₁₉N₅O₄	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	104227-87-4	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	BRL-42810			Smiles	CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)COC(=O)C

Solubility

In vitro
Batch:

DMSO : 64 mg/mL ( (199.16 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 64 mg/mL

Ethanol : 48 mg/mL

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
=	×	×

Dilution Calculator Molecular Weight Calculator

In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT05283551	Unknown status	Multiple Sclerosis	Queen Mary University of London	November 25 2020	Phase 2
NCT00878072	Completed	Herpes Labialis	Novartis Pharmaceuticals\|Novartis	March 25 2009	Phase 2\|Phase 3
NCT01154543	Completed	HIV Positive\|Herpes Simplex Genital	Holdsworth House Medical Practice	March 2008	--
NCT00448227	Completed	Herpes Simplex	Novartis	October 2007	Phase 2
NCT00098059	Completed	Herpes Simplex	Novartis Pharmaceuticals\|Novartis	February 2005	Phase 3

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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