Fluorouracil (5-Fluorouracil, 5-FU)

For research use only.

Catalog No.S1209 Synonyms: NSC 19893

137 publications

Fluorouracil (5-Fluorouracil, 5-FU) Chemical Structure

CAS No. 51-21-8

Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.

Selleck's Fluorouracil (5-Fluorouracil, 5-FU) has been cited by 137 publications

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.
Targets
Thymidylate synthase [1]
(Tumor cells)
In vitro

Adrucil is an analogue of uracil with a fluorine atom at the C-5 position in place of hydrogen. It rapidly enters the cell using the same facilitated transport mechanism as uracil. Adrucil is converted intracellularly to several active metabolites: fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine triphosphate (FUTP). The Adrucil metabolite FdUMP binds to the nucleotide-binding site of TS, forming a stable ternary complex with the enzyme and CH2THF, thereby blocking binding of the normal substrate dUMP and inhibiting dTMP synthesis. Metabolite of Adrucil also can be misincorporated into DNA, leading to DNA strand breaks and cell death. The pro-apoptosis effects of Adrucil may be related to its activation of tumor suppressor p53. Loss of p53 function reduces cellular sensitivity to Adrucil. [1] Adrucil is able to inhibit the survival and induce apoptosis of a board range of cancer cells. Adrucil suppresses viabilities of the nasopharyngeal carcinoma cell line CNE2 and HONE1 [2], pancreatic cancer cell lines Capan-1 [3], and human colon carcinoma cell line HT-29 [4] with IC50 of 9 μg/mL, 3 μg/mL, 0.22 μM, 2.5 μM, respectively.

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H292 M1vNXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1vMN|czyqCqwrC= NG\zWGNKSzVyPjCyOUDPxGdxbVy= M2DPPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEm1NVc3Lz5{NEC5OVE4PjxxYU6=
HL-60 NFWxO2pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{\xSVczyqCqwrC= NWnyepV{UUN3ME24MlYxOSEQvHevcWw> MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDB7NUG3Okc,OjRyOUWxO|Y9N2F-
HT-29 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1PwdVczyqCqwrC= MX3JR|UxRiB{NTFOwIcwdUx? MoPyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyOUWxO|YoRjJ2MEm1NVc3RC:jPh?=
MCF-7 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3rrcVczyqCqwrC= NWnC[5plUUN3ME2yNEDPxGdxbVy= NGTGNFI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEC5OVE4Pid-MkSwPVUyPzZ:L3G+
L1210/0 MUTGeY5kfGmxbjDhd5NigQ>? MXXF[oZm[3Rib36gUFEzOTBxMDDj[YxteyCrbjDjeYx1fXKnLDDJR|UxKD1iMD6zJO69VS5? M1njZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkKyO|goRjJ|NkKyO|g9N2F-
CCRF-CEM Mn7lSpVv[3Srb36gZZN{[Xl? M1zsPGVn\mWldDDvckBES1KILVPFUUBk\WyuczDpckBkfWy2dYLlMEBKSzVyIE2gNkDPxE1w M3ntSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkKyO|goRjJ|NkKyO|g9N2F-
P388 MnjjRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MWK0PEBpenN? M3Hr[GFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViUEO4PEBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD62NFkh|ryPLh?= M{i2O|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{i0OFkoRjJ5N{i0OFk9N2F-
HT-29 NH3TNmdCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MYe5OkBpenN? MmKzRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKVD2yPUBk\WyuczDh[pRmeiB7NjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD62PUDPxE1w M2jPPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{i0OFkoRjJ5N{i0OFk9N2F-
L1210 NUjwTIU5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYfJcohq[mm2aX;uJI9nKGOnbHyg[5Jwf3SqIH;mJGwyOjFyIH3veZNmKEyndXvlcYliKGOnbHzzMEBKSzVyIE2gNE4{KM7:TT6= MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTZ5M{e1K|4zQTZ5M{e1QE9iRg>?
L1210 NFLqU2lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mm\TR49v[2WwdILheIlwdiC{ZYH1bZJm\CCob4KgeIhmKDVyJTDpcohq[mm2aX;uJI9nKGe{b4f0bEBw\iCOMUKxNEBud3W|ZTDs[ZVs\W2rYTDj[YxteyCrbjDjeYx1fXKnLDDJR|UxKD1iMD61JO69VS5? NUToOFNVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{GyNFI6OCd-N{GyNFI6ODxxYU6=
CCRF-CEM NHPWTYhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXTDc45k\W62cnH0bY9vKHKncYXpdoVlKG[xcjD0bIUhPTBnIHnubIljcXSrb36gc4Yh\3Kxd4ToJI9nKEOFUl[tR2VOKGi3bXHuJIxmfWunbXnhJINmdGy|IHnuJIN2dHS3cnWsJGlEPTBiPTC1JO69VS5? NGn5cJc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95MUKwNlkxLz55MUKwNlkxRC:jPh?=
L1210 M3rOVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEXjZlA1QCCqcoO= MoHpTY4hfmm2cn:g[5Jwf3SqIHnubIljcXSrb36gc4YhVDF{MUCgZ4VtdHNiNEigbI92enNiYX\0[ZIh[WSvaX7pd5Rz[XSrb36gc4Yh[2:vcH;1coQtKEmFNUCgQUAxNjF{IN88UU4> NHjVbIY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95NkK5PFA3Lz55NkK5PFA3RC:jPh?=
L1210 MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoXwNlQhcHK| NYjLV|NnUW5idnn0do8h\3Kxd4ToJIlvcGmkaYTpc44hd2ZiTEGyNVAh[2WubIOgNlQhcG:3coOgZYZ1\XJiYXTtbY5qe3S{YYTpc44hd2ZiY3;tdI92dmRuIFnDOVAhRSByLkKyJO69VS5? Mm\2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwPzZ{OUiwOkc,PzZ{OUiwOlww[T5?
L1210 MmTaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGXpRmQ5KGi{cx?= NYDsN40xUW5idnn0do8h\3Kxd4ToJIlvcGmkaYTpc44hd2ZiTEGyNVAh[2WubIOgPEBpd3W{czDh[pRmeiCjZH3pcol{fHKjdHnvckBw\iClb33wc5Vv\CxiSVO1NEA:KDBwNkOg{txONg>? MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek84PjJ7OEC2K|44PjJ7OEC2QE9iRg>?
L1210 NVHOfYhGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1fBUFIhcHK| MlTsTY4hfmm2cn:g[5Jwf3SqIHnubIljcXSrb36gc4YhVDF{MUCgZ4VtdHNiMjDoc5VzeyCjZoTldkBi\G2rbnnzeJJifGmxbjDv[kBkd22yb4Xu[EwhUUN3MDC9JFIvOiEQvF2u NX;DSWJLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{[yPVgxPid-N{[yPVgxPjxxYU6=
CHO M37wXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4KxNGdzd3e2aDDpcohq[mm2b4L5JIFkfGm4aYT5JIFo[Wmwc4SgR2hQKGOnbHzzJIlvKGO3bIT1doUvNCCLQ{WwJF0hPSEQvF2u MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek84QDV|M{SyK|44QDV|M{SyQE9iRg>?
SCLC NVrnTGU{S3m2b4TvfIlkcXS7IHHzd4F6 NX\DbnJiS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0OOQzDj[YxteyC{ZYPpd5RidnRidH:gZ4l{eGyjdHnuJEhUS0yFL1PESHAqNCCLQ{WwJF0hQC52IN88UU4> MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek85OjV6OEO1K|45OjV6OEO1QE9iRg>?
T-24 NIPjdFhEgXSxdH;4bYNqfHliYYPzZZk> NGLP[3dV\XO2ZXSg[o9zKGO7dH;0c5hq[2m2eTDh[4FqdnO2IHHueIlo\W5ibnXnZZRqfmViVD2yOEBjdGGmZHXyJINiemOrbn;tZUBk\WyuczDoZZZqdmdib37sfUA{NTVnIHHueIlo\W5iZYjwdoV{e2mxbjygTWM2OCB;IESuNUDPxE1w NIHObW89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi96NEm2PVI3Lz56NEm2PVI3RC:jPh?=
791T M3TtZmN6fG:2b4jpZ4l1gSCjc4PhfS=> Ml33WIV{fGWmIH\vdkBkgXSxdH;4bYNqfHliYXfhbY5{fCCjboTp[4VvKHCxc3n0bZZmKDd7MWSgc5N1\W:|YYLjc41iKGOnbHzzJIhifmmwZzDvcox6KDNvNTWgZY51cWenbjDlfJBz\XO|aX;uMEBKSzVyIE2gOU42KM7:TT6= MlvnQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQDR7NkmyOkc,QDR7NkmyOlww[T5?
9L MYLBcpRq[2GwY3XyJIF{e2G7 M3XRbnRme3SnZDDpckB3cXS{bzDmc5Ih[W62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KDmOIHPlcIx{NCCLQ{WwJF0hOSEQvF2u NXWzZ|g6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUCwO|I3QDNpPkGwNFczPjh|PD;hQi=>
SK-MEL-28 NFzud|dCdnSrY3HuZ4VzKGG|c3H5 NWXWVG9KXGW|dHXkJIlvKH[rdILvJIZweiCjboTpZ4Fv[2W{IHHjeIl3cXS7IHHnZYlve3RiU1utUWVNNTJ6IHPlcIx{NCCLQ{WwJF0hPC53IN88UU4> NGTRbYY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMEC3NlY5Oyd-MUCwO|I3QDN:L3G+
PBM M2jTUGN6fG:2b4jpZ4l1gSCjc4PhfS=> Mom4WIV{fGWmIHnuJJZqfHKxIH\vdkBkgXSxdH;4bYNqfHliYXfhbY5{fCCSQl2gZ4VtdHNuIFnDOVAhRSB3IN88UU4> NYTaU4hxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUCwO|I3QDNpPkGwNFczPjh|PD;hQi=>
Vero NX3PV|BHS3m2b4TvfIlkcXS7IHHzd4F6 MWTU[ZN1\WRiaX6geol1em9iZn;yJIN6fG:2b4jpZ4l1gSCjZ3HpcpN1KF[ncn:gZ4VtdHNuIFnDOVAhRSB4LkixJO69VS5? MlzEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTByN{K2PFMoRjFyMEeyOlg{RC:jPh?=
SK-MES-1 NF7sbIFCdnSrY3HuZ4VzKGG|c3H5 NYnycldZXGW|dHXkJIlvKH[rdILvJIZweiCjboTpZ4Fv[2W{IHHjeIl3cXS7IHHnZYlve3RiU1utUWVUNTFiY3XscJMtKEmFNUCgQUAyOy5zIN88UU4> Mn;aQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTByN{K2PFMoRjFyMEeyOlg{RC:jPh?=
HepG2 MXHBcpRq[2GwY3XyJIF{e2G7 MVjU[ZN1\WRiaX6geol1em9iZn;yJIFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBJ\XCJMjDj[YxteyxiSVO1NEA:KDN5Lkmg{txONg>? NF33WFk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMEC3NlY5Oyd-MUCwO|I3QDN:L3G+
MCF-7 M4XwZmFvfGmlYX7j[ZIh[XO|YYm= M1XmPHRme3SnZDDpckB3cXS{bzDmc5Ih[W62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KE2FRj23JINmdGy|LDDJR|UxKD1iNEGg{txONg>? NHLmO5A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMEC3NlY5Oyd-MUCwO|I3QDN:L3G+
L1210 NWq4cFNKS3m2b4TvfIlkcXS7IHHzd4F6 NGDVc5hKdiC4aYTyc{BkgXSxdH;4bYNqfHliYXfhbY5{fCCvdYLpcoUhVGW3a3XtbYEhVDF{MUCgZ4VtdHNwLDDJR|UxKD1iMD62NkDPxE1w NFnFd|A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMEKyPVY{PCd-MUCyNlk3OzR:L3G+
KB NGHhNYdEgXSxdH;4bYNqfHliYYPzZZk> NXezWnNUUW5idnn0do8h[3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hd3KjbDDldIll\XKvb3nkJINiemOrbn;tZUBMSiClZXzsd{4tKEmFNUCgQUAzNjNizszNMi=> M1vwcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFyMkK5OlM1Lz5zMEKyPVY{PDxxYU6=
L1210 MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWL0NI5mS2:wY3XueJJifGmxbjDy[ZF2cXKnZDD0c{BqdmirYnn0JFUxLSCxZjDj[YxtKGe{b4f0bEBwdiCvdYLpcoUhVDF{MUCgZ4VtdHNwLDDJR|UxKD1iMD6yPEDPxE1w NGT6[ZY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUC1Nlc6QCd-MUGwOVI4QTh:L3G+
P388 D1 NGXMWGFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M32xVGNwdmOnboTyZZRqd25icnXxeYlz\WRidH:gbY5pcWKrdDC1NEUhd2ZiY3XscEBoem:5dHigc44hdXW{aX7lJHA{QDhiREGgZ4VtdHNwLDDJR|UxKD1iMD60PUDPxE1w NVjTT5FxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUGwOVI4QThpPkGxNFUzPzl6PD;hQi=>
Molt 4/C8 MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHfZUXNEd26lZX70doF1cW:wIILldZVqemWmIITvJIlvcGmkaYSgOVAmKG:oIHPlcIwh\3Kxd4ToJI9vKGi3bXHuJG1wdHRiND;DPEBk\Wyucz6sJGlEPTBiPTCyN{DPxE1w MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTB3Mke5PEc,OTFyNUK3PVg9N2F-
L1210 Ml;nS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NF;XdHk1QCCqcoO= MV;Hdo94fGhiaX7obYJqfGmxbjDpckBNOTJzMDDtc5V{\SCOZYXr[Y1q[SClZXzsd{Bnd3JiYTD0doVifG2nboSgeIlu\SCxZjC0PEBpeixiSVO1NEA:KDBwMUK1JO69VS5? M1LUOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzME[zOlI2Lz5zMUC2N|YzPTxxYU6=
L1210 NHq1doFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYiyOEBpenN? NHvpeIZIem:5dHigbY5pcWKrdHnvckBqdiCOMUKxNEBud3W|ZTDM[ZVs\W2rYTDj[YxteyCob4KgZUB1emWjdH3lcpQhfGmvZTDv[kAzPCCqcjygTWM2OCB;IECuNlIh|ryPLh?= M3XURlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzME[zOlI2Lz5zMUC2N|YzPTxxYU6=
L1210 Mo\QS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlLwPEBpenN? NIL3bI1Iem:5dHigbY5pcWKrdHnvckBqdiCOMUKxNEBud3W|ZTDM[ZVs\W2rYTDj[YxteyCob4KgZUB1emWjdH3lcpQhfGmvZTDv[kA5KGi{LDDJR|UxKD1iMD62N{DPxE1w M{fvOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzME[zOlI2Lz5zMUC2N|YzPTxxYU6=
L1210 M3LkVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MW[yJIhzew>? NE\JZXBIem:5dHigbY5pcWKrdHnvckBqdiCOMUKxNEBud3W|ZTDM[ZVs\W2rYTDj[YxteyCob4KgZUB1emWjdH3lcpQhfGmvZTDv[kAzKGi{LDDJR|UxKD1iMj6yJO69VS5? NV7nN4hrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUGwOlM3OjVpPkGxNFY{PjJ3PD;hQi=>
Colon 26-L5 NX[4RmxGSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= Mk[wO|IhcHK| NILsXodCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JI1wfXOnIFPvcI9vKDJ4LVy1JINmdGy|IHHzd4V{e2WmIHHzJINmdGxidnnhZoltcXS7IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLkWg{txONg>? M3\XRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzNUe1PVQzLz5zMUW3OVk1OjxxYU6=
B16-BL6 M3zwWmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MojSO|IhcHK| M4jrVmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViQkG2MWJNPiClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE43KM7:TT6= NI\FZ5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUW3OVk1Oid-MUG1O|U6PDJ:L3G+
HT1080 MkHoRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NEDofJI4OiCqcoO= NXTVSI46SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWFExQDBiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEvPSEQvF2u NE\z[W89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUW3OVk1Oid-MUG1O|U6PDJ:L3G+
L1210 M{\mZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVm0PEBpenN? MXTHdo94fGhiaX7obYJqfGmxbjDpckBNOTJzMDDtc5V{\SCuZYXr[Y1q[SClZXzsd{Bi\nSncjC0PEBpeiC2cnXheI1mdnRuIFnDOVAhRSByLkKg{txONg>? Mn;iQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF5MkixPVMoRjFzN{K4NVk{RC:jPh?=
L1210 MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1TsNFI1KGi{cx?= MXHHdo94fGhiaX7obYJqfGmxbjDpckBNOTJzMDDtc5V{\SCuZYXr[Y1q[SClZXzsd{Bi\nSncjCyOEBpKHS{ZXH0cYVvfCxiSVO1NEA:KDBwM{[g{txONg>? MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTd{OEG5N{c,OTF5MkixPVM9N2F-
L1210 NGTjbGVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2LaNlghcHK| M2PJUGdzd3e2aDDpcohq[mm2aX;uJIlvKExzMkGwJI1wfXOnIHzleYtmdWmjIHPlcIx{KGGodHXyJFghcCC2cnXheI1mdnRuIFnDOVAhRSBzLkCxJO69VS5? NEDWdlc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUeyPFE6Oyd-MUG3NlgyQTN:L3G+
L1210 NYnQVZA6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NY\4R|FlOiCqcoO= NISwWZhIem:5dHigbY5pcWKrdHnvckBqdiCOMUKxNEBud3W|ZTDs[ZVs\W2rYTDj[YxteyCjZoTldkAzKGi{IITy[YF1dWWwdDygTWM2OCB;IEKuOUDPxE1w M1zUe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzN{K4NVk{Lz5zMUeyPFE6OzxxYU6=
HL60 NXXFU|I1TnWwY4Tpc44h[XO|YYm= M3KwdmlvKH[rdILvJIlvcGmkaYTvdpkh[2:wY3XueJJifGmxbjDh[4FqdnO2IIDyc4xq\mW{YYTpc44hd2ZiSFy2NEBk\WyuczygTWM2OCB;IEGuOUDPxE1w MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjh5N{W5N{c,OTJ6N{e1PVM9N2F-
HT1080 MnjyRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NHPzdHo4OiCqcoO= NXzQTlc3SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWFExQDBiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFMvPyEQvF2u NID0SmY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNE[0NFUyOyd-MUS2OFA2OTN:L3G+
HCT116 MlPrR5l1d3SxeHnjbZR6KGG|c3H5 MVy5OkBpenN? MVHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgPVYhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQvQTNizszNMi=> MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTN6N{[zPUc,OTV|OEe2N|k9N2F-
DLD1 MYDDfZRwfG:6aXPpeJkh[XO|YYm= NHfiWoE6PiCqcoO= MX3DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDEUGQyKGOnbHzzJIFnfGW{IEm2JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC3MlM5KM7:TT6= NVrKdXQ3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWzPFc3OzlpPkG1N|g4PjN7PD;hQi=>
HeLaS3 MkjiR5l1d3SxeHnjbZR6KGG|c3H5 MnjEO|IhcHK| NGC4[4NEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjU{OgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KFeVVEGgZZN{[XluIFnDOVAhRSB3LkSg{txONg>? MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTN6N{[1Okc,OTV|OEe2OVY9N2F-
HeLaS3 NHXBUmpEgXSxdH;4bYNqfHliYYPzZZk> NXz6Wo1TS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYWOzJINmdGy|IHL5JHdUXDFiYYPzZZktKEmFNUCgQUA2NjRizszNMi=> M4jGNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3NU[4O|cyLz5zNUW2PFc4OTxxYU6=
MCF-7 M4jSXWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MmnzRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgbY4hVUOILUegbJVu[W5iYoLlZZN1KGOjbnPldkBk\WyuczygTWM2OCB;IESuPEDPxE1w MmXUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV4NUi4O|UoRjF3NkW4PFc2RC:jPh?=
MDA-MB 231 NX\Db4t3SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NFLJXVlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBqdiCPRFGtUWIhOjNzIHj1cYFvKGK{ZXHzeEBk[W6lZYKgZ4VtdHNuIFnDOVAhRSB7Lk[g{txONg>? M1zIRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3NkW4PFc2Lz5zNU[1PFg4PTxxYU6=
A549 MX;DfZRwfG:6aXPpeJkh[XO|YYm= MkG2PVYhcHK| NUHWUlFJS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA6PiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOS52IN88UU4> NYLVRlRJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[0PVk{OTdpPkG2OFk6OzF5PD;hQi=>
HCT8 NHPmRnlEgXSxdH;4bYNqfHliYYPzZZk> NHfod4I6PiCqcoO= MkjYR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVQCClZXzsd{Bi\nSncjC5OkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOE4zKM7:TT6= M3j6RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NEm5N|E4Lz5zNkS5PVMyPzxxYU6=
BEL-7402 M2PMWmN6fG:2b4jpZ4l1gSCjc4PhfS=> NH[wTWs6PiCqcoO= NEj6cYdEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBDTUxvN{SwNkBk\WyuczDh[pRmeiB7NjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iND6yJO69VS5? MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjR7OUOxO{c,OTZ2OUmzNVc9N2F-
A2780 Mk\DR5l1d3SxeHnjbZR6KGG|c3H5 NGfwT2s6PiCqcoO= MWnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBNlc5OCClZXzsd{Bi\nSncjC5OkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOUDPxE1w NH\iSZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkS5PVMyPyd-MU[0PVk{OTd:L3G+
BGC823 MoX5R5l1d3SxeHnjbZR6KGG|c3H5 MmPKPVYhcHK| MXjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDCS2M5OjNiY3XscJMh[W[2ZYKgPVYhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFUvPCEQvF2u NW\vc|VFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[0PVk{OTdpPkG2OFk6OzF5PD;hQi=>
HCT116 NFvaNVlEgXSxdH;4bYNqfHliYYPzZZk> MVjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMtKEmFNUCgQUAzNjB2IN88UU4> NU\vSXFURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[5PVY3PTdpPkG2PVk3PjV5PD;hQi=>
COLO205 MWXDfZRwfG:6aXPpeJkh[XO|YYm= NIrWRm5EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBEV0yRMkC1JINmdGy|LDDJR|UxKD1iMz6zPUDPxE1w MmLZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ7OU[2OVcoRjF4OUm2OlU4RC:jPh?=
RPMI8226 NXHWXY8zS3m2b4TvfIlkcXS7IHHzd4F6 M3fGd2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHJRVUl6MkK2JINmdGy|LDDJR|UxKD1iMz61OUDPxE1w MnrEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ7OU[2OVcoRjF4OUm2OlU4RC:jPh?=
HCC2998 NIrJN|hEgXSxdH;4bYNqfHliYYPzZZk> NFXK[|VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS0N{OUm4JINmdGy|LDDJR|UxKD1iNT63OUDPxE1w NGPnZ2s9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkm5OlY2Pyd-MU[5PVY3PTd:L3G+
HCT15 NXrlToo1S3m2b4TvfIlkcXS7IHHzd4F6 MlzkR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVOTViY3XscJMtKEmFNUCgQUA3NjZzIN88UU4> MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjl7Nk[1O{c,OTZ7OU[2OVc9N2F-
KM12 NH\FXYhEgXSxdH;4bYNqfHliYYPzZZk> M1\jc2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGtOOTJiY3XscJMtKEmFNUCgQUA4Njl2IN88UU4> NILjcow9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkm5OlY2Pyd-MU[5PVY3PTd:L3G+
SW620 MoDER5l1d3SxeHnjbZR6KGG|c3H5 MX\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTW|YzOCClZXzsd{whUUN3MDC9JFE5NjZizszNMi=> NEf4d3M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkm5OlY2Pyd-MU[5PVY3PTd:L3G+
KB Mom0R5l1d3SxeHnjbZR6KGG|c3H5 NXTTfpNkPDhiaILz M1;qN2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGtDKGOnbHzzJIFnfGW{IES4JIhzeyxiSVO1NEA:KDF|LkSg{txONg>? NVO2e2IzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUewNFAxOzFpPkG3NFAxODNzPD;hQi=>
HT29 M1;BfWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MkDvRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDIWFI6KGOnbHzzMEBKSzVyIE2gO{4{KM7:TT6= M4XGRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGwNVA2Lz5zN{GxNFExPTxxYU6=
Vero M3uyZ2N6fG:2b4jpZ4l1gSCjc4PhfS=> MYrDfZRwfG:6aXPpeJkh[WejaX7zeEBX\XKxIHPlcIx{NCCLQ{WwJF0hOC5{IN88UU4> M{jyXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkO0N|A{Lz5zN{KzOFMxOzxxYU6=
SW1116 NWTJVpVKS3m2b4TvfIlkcXS7IHHzd4F6 MljpR5l1d3SxeHnjbZR6KGGpYXnud5QhW1dzMUG2JINmdGy|IHL5JG1VXCClb3zvcYV1emmlIH3leIhw\CxiSVO1NEA:KDN5IN88UU4> NEnZfFE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{K1N|g3OSd-MUeyOVM5PjF:L3G+
HL60 MYHDfZRwfG:6aXPpeJkh[XO|YYm= M2nYcFQ5KGi{cx?= Mn;QR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGw3OCClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE4yPiEQvF2u Mkj3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd{OUGwOFAoRjF5MkmxNFQxRC:jPh?=
Bel7402 MoTNR5l1d3SxeHnjbZR6KGG|c3H5 NUfXSIMxPDhiaILz NVj6OmxPS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSmWuN{SwNkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMkOuNlEh|ryPLh?= NFfZOWk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{K5NVA1OCd-MUeyPVExPDB:L3G+
BGC823 MUHDfZRwfG:6aXPpeJkh[XO|YYm= NEWyTlc1QCCqcoO= MXPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDCS2M5OjNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFMyNjF4IN88UU4> NGO5UGQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{K5NVA1OCd-MUeyPVExPDB:L3G+
HT29 NX21UlZOS3m2b4TvfIlkcXS7IHHzd4F6 NFL5bGJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXDJ7IHPlcIx{KGK7IF3UWEBucWO{b3Hzd4F6NCCLQ{WwJF0hOC54IN88UU4> Mnr6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd|MkCyOFYoRjF5M{KwNlQ3RC:jPh?=
Hep 3B NFPacW9EgXSxdH;4bYNqfHliYYPzZZk> NYDkdoN3S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyIEPCJINmdGy|IHL5JG1VXCCvaXPyc4F{e2G7LDDJR|UxKD1iMD62JO69VS5? NVG3XGdnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezNlAzPDZpPkG3N|IxOjR4PD;hQi=>
MCF7 M4PhVGN6fG:2b4jpZ4l1gSCjc4PhfS=> NGrT[VREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGK7IF3UWEBucWO{b3Hzd4F6NCCLQ{WwJF0hOS53IN88UU4> NHm1WZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{OyNFI1Pid-MUezNlAzPDZ:L3G+
A549 MWTDfZRwfG:6aXPpeJkh[XO|YYm= MVvDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIJ6KE2WVDDtbYNzd2G|c3H5MEBKSzVyIE2gN{4yKM7:TT6= NEi2[YM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{OyNFI1Pid-MUezNlAzPDZ:L3G+
MCF7 NFTwZo1EgXSxdH;4bYNqfHliYYPzZZk> NV3CSVl3PzJiaILz M2[zN2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgO|IhcHK|LDDJR|UxKD1iND64JO69VS5? NYjacYlRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezN|YxPzRpPkG3N|M3ODd2PD;hQi=>
MDA-MB-231 NIjF[nFEgXSxdH;4bYNqfHliYYPzZZk> MmPqO|IhcHK| M2i1VmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj2yN|Eh[2WubIOgZYZ1\XJiN{KgbJJ{NCCLQ{WwJF0hQS54IN88UU4> MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzN|NkC3OEc,OTd|M{[wO|Q9N2F-
Caco-2 M2[1bGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFz0dpIyOCCmYYnz NED6U4dIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBE[WOxLUKgZ4VtdHNiYX\0[ZIhOTBiZHH5d{whUUN3MDC9JFEvPSEQvF2u M{LjWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{O3NVk{Lz5zN{OzO|E6OzxxYU6=
L1210/0 NV\CZ5doS3m2b4TvfIlkcXS7IHHzd4F6 M3vp[VQ5KGi{cx?= NHTEPWJEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBNOTJzMD:wJINmdGy|IHHmeIVzKDR6IHjyd{whUUN3MDC9JFAvOzFizszNMi=> NXTnUId6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOFExPjBpPkG3N|QyODZyPD;hQi=>
HCT116 M1vWdmFvfGm2dX3vdkBie3OjeR?= NVf3U29YSW62aYT1cY9zKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{NCCJSUWwJF0hOC5|OUixNUDPxE1w NVzQcIZiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFYxPzdpPkG3OFQ3ODd5PD;hQi=>
NCI-H460 M3zSPGFvfGm2dX3vdkBie3OjeR?= M2H5cmFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7DTU1JPDZyIHPlcIx{NCCJSUWwJF0hOSEQvF2u MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR2NkC3O{c,OTd2NE[wO|c9N2F-
SF539 MYfBcpRqfHWvb4KgZZN{[Xl? MVzBcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVRkWzPUBk\WyuczygS2k2OCB;IEGuNlU5QTNizszNMi=> MkTLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2NE[wO|coRjF5NES2NFc4RC:jPh?=
MCF7 NEnHR2NCdnSrdIXtc5Ih[XO|YYm= MnXiRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczygS2k2OCB;IEGuOVg1QDlizszNMi=> MoLvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2NE[wO|coRjF5NES2NFc4RC:jPh?=
HCC2998 NV3LZpo3SW62aYT1cY9zKGG|c3H5 NWnvemc1SW62aYT1cY9zKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGNEOjl7ODDj[YxteyxiR1m1NEA:KDFwNUi0PFkh|ryPLh?= NW\FXI5KRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFYxPzdpPkG3OFQ3ODd5PD;hQi=>
A549 NGXJSmNCdnSrdIXtc5Ih[XO|YYm= MX3BcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDNUS5JINmdGy|LDDHTVUxKD1iMT65PVUzPiEQvF2u M4jSSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NES2NFc4Lz5zN{S0OlA4PzxxYU6=
CAKI-1 NYDhcmUxSW62aYT1cY9zKGG|c3H5 MmrWRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1HLTU0yKGOnbHzzMEBIUTVyIE2gN{46QDFyNzFOwG0v MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR2NkC3O{c,OTd2NE[wO|c9N2F-
SR Mm\WRY51cXS3bX;yJIF{e2G7 MULBcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVUjDj[YxteyxiR1m1NEA:KDNwOUixNFch|ryPLh?= Mon5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2NE[wO|coRjF5NES2NFc4RC:jPh?=
UO31 NIHEXJRCdnSrdIXtc5Ih[XO|YYm= M2fGT2FvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGXPN|Eh[2WubIOsJGdKPTBiPTC1MlAyOTh5IN88UU4> NITQTJU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S0OlA4Pyd-MUe0OFYxPzd:L3G+
RPMI8226 MlHERY51cXS3bX;yJIF{e2G7 NIP5NVlCdnSrdIXtc5Ih[WO2aY\peJkh[WejaX7zeEBpfW2jbjDSVG1KQDJ{NjDj[YxteyxiR1m1NEA:KDVwMEGxPFch|ryPLh?= M1:3XVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NES2NFc4Lz5zN{S0OlA4PzxxYU6=
HCT15 MlPIRY51cXS3bX;yJIF{e2G7 MlO2RY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPUNVUh[2WubIOsJGdKPTBiPTC2MlMxQTV5IN88UU4> M2fvPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NES2NFc4Lz5zN{S0OlA4PzxxYU6=
HT29 MWHBcpRqfHWvb4KgZZN{[Xl? M1LrOWFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjUNlkh[2WubIOsJGdKPTBiPTC2MlMxQTV5IN88UU4> M3vuTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NES2NFc4Lz5zN{S0OlA4PzxxYU6=
LOX IMVI MYHBcpRqfHWvb4KgZZN{[Xl? Mkm3RY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTF;YJGlOXkliY3XscJMtKEeLNUCgQUA3NjNyOUW3JO69VS5? NIPYZ4Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S0OlA4Pyd-MUe0OFYxPzd:L3G+
COLO205 NGDvS|RCdnSrdIXtc5Ih[XO|YYm= MkTRRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1;MU|IxPSClZXzsd{whT0l3MDC9JFYvOzB7NUeg{txONg>? NGPpWZU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S0OlA4Pyd-MUe0OFYxPzd:L3G+
KM12 M4jKR2FvfGm2dX3vdkBie3OjeR?= MmDyRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iS12xNkBk\WyuczygS2k2OCB;IEGwJO69VS5? MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR2NkC3O{c,OTd2NE[wO|c9N2F-
ACHN NWTqd5hxSW62aYT1cY9zKGG|c3H5 MULBcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDQ1jOJINmdGy|LDDHTVUxKD1iMUCg{txONg>? NFrtTGw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S0OlA4Pyd-MUe0OFYxPzd:L3G+
DU145 M1r3eWFvfGm2dX3vdkBie3OjeR?= MVXBcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCGVUG0OUBk\WyuczygS2k2OCB;IEGwJO69VS5? MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR2NkC3O{c,OTd2NE[wO|c9N2F-
A498 MVXBcpRqfHWvb4KgZZN{[Xl? M3rldWFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG0PVgh[2WubIOsJGdKPTBiPTCxNEDPxE1w M1\lZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NES2NFc4Lz5zN{S0OlA4PzxxYU6=
MDA-MB-435 NUfUSZJoSW62aYT1cY9zKGG|c3H5 NF7u[JZCdnSrdIXtc5Ih[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvNEO1JINmdGy|LDDHTVUxKD1iMUCg{txONg>? NWXq[Gg1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFYxPzdpPkG3OFQ3ODd5PD;hQi=>
MOLT4 NF2ycWVCdnSrdIXtc5Ih[XO|YYm= M17xfmFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3PUHQ1KGOnbHzzMEBIUTVyIE2gNVIvPTh7MjFOwG0v NHzVUm49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S0OlA4Pyd-MUe0OFYxPzd:L3G+
NCI-H23 MXXBcpRqfHWvb4KgZZN{[Xl? NYnDZnFLSW62aYT1cY9zKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUmNKNUh{MzDj[YxteyxiR1m1NEA:KDF{LkW4PVIh|ryPLh?= M{\vUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NES2NFc4Lz5zN{S0OlA4PzxxYU6=
IGROV1 NFHj[45CdnSrdIXtc5Ih[XO|YYm= MlziRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSVfSU3YyKGOnbHzzMEBIUTVyIE2gNVIvPTh7MjFOwG0v M2i2Z|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NES2NFc4Lz5zN{S0OlA4PzxxYU6=
UACC62 NFm2OlJCdnSrdIXtc5Ih[XO|YYm= MV3BcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCXQVPDOlIh[2WubIOsJGdKPTBiPTCxNk42QDl{IN88UU4> MnHmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2NE[wO|coRjF5NES2NFc4RC:jPh?=
SK-MEL-5 NV7lU|ZDSW62aYT1cY9zKGG|c3H5 MkLFRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU1utUWVNNTViY3XscJMtKEeLNUCgQUAyOi53OEmyJO69VS5? NWX1UXh2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFYxPzdpPkG3OFQ3ODd5PD;hQi=>
786-0 MorURY51cXS3bX;yJIF{e2G7 M1\4dGFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIEe4Ok0xKGOnbHzzMEBIUTVyIE2gNVIvPTh7MjFOwG0v M1rMTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NES2NFc4Lz5zN{S0OlA4PzxxYU6=
K562 MnjWRY51cXS3bX;yJIF{e2G7 NGK5NG5CdnSrdIXtc5Ih[WO2aY\peJkh[WejaX7zeEBpfW2jbjDLOVYzKGOnbHzzMEBIUTVyIE2gNVkvQTV{NjFOwG0v NHPhOZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S0OlA4Pyd-MUe0OFYxPzd:L3G+
HOP62 NHTrZoZCdnSrdIXtc5Ih[XO|YYm= NH\oRm1CdnSrdIXtc5Ih[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIU3A3OiClZXzsd{whT0l3MDC9JFE6Njl3Mk[g{txONg>? MkjOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2NE[wO|coRjF5NES2NFc4RC:jPh?=
MALME-3M NHzwdpFCdnSrdIXtc5Ih[XO|YYm= MlfCRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVHMUWUuO01iY3XscJMtKEeLNUCgQUAyQS57NUK2JO69VS5? MknKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2NE[wO|coRjF5NES2NFc4RC:jPh?=
OVCAR8 M4fQdmFvfGm2dX3vdkBie3OjeR?= MnnJRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iT2\DRXI5KGOnbHzzMEBIUTVyIE2gNVkvQTV{NjFOwG0v Ml7NQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2NE[wO|coRjF5NES2NFc4RC:jPh?=
HL60 (TB) MXHBcpRqfHWvb4KgZZN{[Xl? NXvkcm9oSW62aYT1cY9zKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGw3OCBqVFKpJINmdGy|LDDHTVUxKD1iMUmuPVUzPiEQvF2u NHTzW|I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S0OlA4Pyd-MUe0OFYxPzd:L3G+
NCI-H322 NV\C[mFbSW62aYT1cY9zKGG|c3H5 NGfUWG5CdnSrdIXtc5Ih[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kuUDN{MjDj[YxteyxiR1m1NEA:KDF7Lkm1NlYh|ryPLh?= Mlm2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2NE[wO|coRjF5NES2NFc4RC:jPh?=
SN12C NIrJXXRCdnSrdIXtc5Ih[XO|YYm= NWrXS5NlSW62aYT1cY9zKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV24yOkNiY3XscJMtKEeLNUCgQUAzPS5zMUi5JO69VS5? NX;NeWJpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFYxPzdpPkG3OFQ3ODd5PD;hQi=>
OVCAR-3 MojPRY51cXS3bX;yJIF{e2G7 Mlz1RY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iT2\DRXIuOyClZXzsd{whT0l3MDC9JFI2NjFzOEmg{txONg>? M1Psc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NES2NFc4Lz5zN{S0OlA4PzxxYU6=
SW620 NVfHcZp4SW62aYT1cY9zKGG|c3H5 M1LMWWFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPXOlIxKGOnbHzzMEBIUTVyIE2gNlUvOTF6OTFOwG0v MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR2NkC3O{c,OTd2NE[wO|c9N2F-
CCRF-CEM NILPOmlCdnSrdIXtc5Ih[XO|YYm= M{\I[WFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFPDVmYuS0WPIHPlcIx{NCCJSUWwJF0hOzFwNkKyPEDPxE1w NX\xbHJ3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFYxPzdpPkG3OFQ3ODd5PD;hQi=>
U251 M2W4T2FvfGm2dX3vdkBie3OjeR?= NX;pSHVrSW62aYT1cY9zKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWVI2OSClZXzsd{whT0l3MDC9JFM6NjhzMEeg{txONg>? MnLOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2NE[wO|coRjF5NES2NFc4RC:jPh?=
NCI-H522 M{XT[2FvfGm2dX3vdkBie3OjeR?= Mn\NRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWg2OjJiY3XscJMtKEeLNUCgQUA{QS56MUC3JO69VS5? Ml3vQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2NE[wO|coRjF5NES2NFc4RC:jPh?=
NCI/ADR-RES NVvFdXhJSW62aYT1cY9zKGG|c3H5 NEWxO|FCdnSrdIXtc5Ih[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kwSUSULWLFV{Bk\WyuczygS2k2OCB;IEO5MlgyODdizszNMi=> MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR2NkC3O{c,OTd2NE[wO|c9N2F-
SW480 Mlz2RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MoW0O|IhcHK| NUS4R29XSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|Q5OCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKG2ndHjv[EwhUUN3MDC9JFgvOSEQvF2u M4\aUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUK0OlU2Lz5zN{WyOFY2PTxxYU6=
MDA-MB-435S MnfBRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NF7SR3A4OiCqcoO= M332O2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTR|NWOgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDt[ZRpd2RuIFnDOVAhRSBzND61JO69VS5? MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV{NE[1OUc,OTd3MkS2OVU9N2F-
HCCLM7 MV;BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NWmxZWRIPzJiaILz M4W4dWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPDUG04KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gNVgvPiEQvF2u M1vOPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUK0OlU2Lz5zN{WyOFY2PTxxYU6=
Caco-2 M1jnOGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mmn4S5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gR4Fkdy1{IHPlcIx{NCCLQ{WwJF0hOS53IN88UU4> MnmyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEixNlkoRjF5NUS4NVI6RC:jPh?=
MCF7 M{PUPWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NXTxXpVjPzJiaILz NX;TOGFlSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyxiSVO1NEA:KDBwMzFOwG0v MkLFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEixPVgoRjF5NUS4NVk5RC:jPh?=
HCT116 NFrKTI5CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NVLVc5V6PzJiaILz MkjXRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZYZ1\XJiN{KgbJJ{NCCLQ{WwJF0hOi56IN88UU4> M3O3e|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUS4NVk5Lz5zN{W0PFE6QDxxYU6=
SW480 M3\3[WFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NFPpTHU4OiCqcoO= MUjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOZNEiwJINmdGy|IHHmeIVzKDd{IHjyd{whUUN3MDC9JFMvPSEQvF2u MnjoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEixPVgoRjF5NUS4NVk5RC:jPh?=
SW48 NW\YZZpFSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MUO3NkBpenN? MUHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOZNEigZ4VtdHNiYX\0[ZIhPzJiaILzMEBKSzVyIE2gOU4{KM7:TT6= NXP6O|BERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1OFgyQThpPkG3OVQ5OTl6PD;hQi=>
DLD1 NGO5Z|VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEPaOmJIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBFVERzIHPlcIx{NCCLQ{WwJF0hPC53IN88UU4> MnrVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NUO2PFUoRjF5NUWzOlg2RC:jPh?=
Caco-2 MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVqxNEBl[Xm| M{T2eGdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGNi[29vMjDj[YxteyCjZoTldkAyOCCmYYnzMEBKSzVyIE2gNU42KM7:TT6= NFXTOnA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W1OVk3QSd-MUe1OVU6Pjl:L3G+
colon cancer cell NXX3S5hpS3m2b4TvfIlkcXS7IHHzd4F6 MX;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDjc4xwdiClYX7j[ZIh[2WubIOsJGdKPTBiPTC1Mlc2KM7:TT6= Mkf6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NkKzOlUoRjF5NU[yN|Y2RC:jPh?=
A549 M1f3dGN6fG:2b4jpZ4l1gSCjc4PhfS=> NIPKVYQ1QCCqcoO= M3PTcmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEF3NEmgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDlwMjFOwG0v NVnqOZdHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2NFQ{QTRpPkG3OlA1Ozl2PD;hQi=>
L1210 NWPtR3ZkS3m2b4P0ZZRq[yCjY4Tpeol1gSCjc4PhfS=> NVXBWG9XS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KG2xdYPlJGwyOjFyIHPlcIx{NCCLQ{WwJF0hOC5{ODFOwG0v NEjE[3g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mzNVg3Oid-MUe5N|E5PjJ:L3G+
CEM M4XhWWN6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= MWXDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1XNJINmdGy|LDDJR|UxKD1iOTFOwG0v M3rIeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUOxPFYzLz5zN{mzNVg3OjxxYU6=
Molt4/C8 NGTi[HREgXSxc4TheIlkKGGldHn2bZR6KGG|c3H5 NIPPfYJEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUY9tfDRxQ{igZ4VtdHNuIFnDOVAhRSB{MzFOwG0v MnvKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7M{G4OlIoRjF5OUOxPFYzRC:jPh?=
Caco-2 MmrsS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkjONVAh\GG7cx?= MXjHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDDZYNwNTJiY3XscJMh[W[2ZYKgNVAh\GG7czygTWM2OCB;IEGuOUDPxE1w M3:wZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MEO3NVk2Lz5zOECzO|E6PTxxYU6=
MCF7 NIrXVmtCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MlvaN{Bl[Xm| MV7BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhOyCmYYnzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDRwM{Kg{txONg>? NWr4UVJHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiwOlkxQTNpPkG4NFY6ODl|PD;hQi=>
MCF7 MlXzRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MVLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNuIFnDOVAhRSB2LkOyJO69VS5? MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDF7NEi2Okc,OThzOUS4OlY9N2F-
embryonic cell MUfGeY5kfGmxbjDhd5NigQ>? M1zIVmlv\HWldHnvckBw\iClbHXheoFo\SCjcoLld5QhcW5iZX3idplwdmmlIHPlcIx{KG:oIIP0ZYdmKDhiWHXuc5B2eyCuYXX2bZMh[myjc4T1cIFmNCCLQ{WwJF0hOjZwODFOwG0v M1zid|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MkexOVU5Lz5zOEK3NVU2QDxxYU6=
HepG2 NWfFOlh6S3m2b4TvfIlkcXS7IHHzd4F6 MoS0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMtKEmFNUCgQUAyQC55IN88UU4> NYLhVW06RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUizNFI{OzZpPkG4N|AzOzN4PD;hQi=>
L1210 M2rG[mFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MlnSNkBl[Xm| NWTxOVhDSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDMNVIyOCClZXzsd{Bi\nSncjCyJIRigXNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE43QSEQvF2u NHTtOZA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOESyOFE2PSd-MUi0NlQyPTV:L3G+
MCF7 NH[wdWlCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M{LZSFMh\GG7cx?= NFO4cGNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlch[2WubIOgZYZ1\XJiMzDkZZl{KGK7IF3UWEBie3OjeTygTWM2OCB;IESuOUDPxE1w MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR{NEG1OUc,OTh2MkSxOVU9N2F-
MiaPaCa2 NGrGd4FCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M2\BS|Mh\GG7cx?= NH3OeHRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3pZXBiS2F{IHPlcIx{KGGodHXyJFMh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUA3NjVizszNMi=> M1uzWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEK0NVU2Lz5zOESyOFE2PTxxYU6=
SW620 NVXvTohlSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NVHxXphVOyCmYYnz MX\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOZNkKwJINmdGy|IHHmeIVzKDNiZHH5d{BjgSCPVGSgZZN{[XluIFnDOVAhRSB6Lkeg{txONg>? MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR{NEG1OUc,OTh2MkSxOVU9N2F-
HepG2 NFSxfoNCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M{XHd|Mh\GG7cx?= Mof2RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZYDHNkBk\WyuczDh[pRmeiB|IHThfZMh[nliTWTUJIF{e2G7LDDJR|UxKD1iOT6yJO69VS5? NV\kXFFnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0NlQyPTVpPkG4OFI1OTV3PD;hQi=>
CEM Ml;CRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M{jCWFMh\GG7cx?= MYrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEOHTTDj[YxteyCjZoTldkA{KGSjeYOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hQS5{MzFOwG0v M1K2cVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEK0NVU2Lz5zOESyOFE2PTxxYU6=
WI38 M1LSS2N6fG:2b4jpZ4l1gSCjc4PhfS=> MnL4N{Bl[Xm| MWPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDXTVM5KGOnbHzzJIFnfGW{IEOg[IF6eyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNEDPxE1w NXToToR6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0NlQyPTVpPkG4OFI1OTV3PD;hQi=>
HeLa Ml\tRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M{PsPVMh\GG7cx?= MUjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEinTHGgZ4VtdHNiYX\0[ZIhOyCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF4IN88UU4> M4XQNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEK0NVU2Lz5zOESyOFE2PTxxYU6=
Molt4/C8 MoTBRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NVr1XHFmOyCmYYnz NHvk[FRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3vcJQ1N0N6IHPlcIx{KGGodHXyJFMh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUAzOCEQvF2u MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR{NEG1OUc,OTh2MkSxOVU9N2F-
colon 26-L5 M1\wUWN6fG:2b4jpZ4l1gSCjc4PhfS=> NV3UNmFIPzJiaILz NHTUPHREgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBkd2yxbjCyOk1NPSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE41PiEQvF2u MmLEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NECyN|MoRjF6NESwNlM{RC:jPh?=
HeLa MlHtR5l1d3SxeHnjbZR6KGG|c3H5 NELicZk4OiCqcoO= MYfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlc4KM7:TT6= M{f2VVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NESwNlM{Lz5zOES0NFI{OzxxYU6=
LLC NEf1SlhEgXSxdH;4bYNqfHliYYPzZZk> MmLIO|IhcHK| MnvwR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgUGxEKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyMlU6KM7:TT6= NF\iR4w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES0NFI{Oyd-MUi0OFAzOzN:L3G+
B16-BL6 M{HZR2N6fG:2b4jpZ4l1gSCjc4PhfS=> MlfWO|IhcHK| NWnjTGtXS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhSjF4LVLMOkBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNT63PEDPxE1w M3Lh[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NESwNlM{Lz5zOES0NFI{OzxxYU6=
A549 NVzy[I1zS3m2b4TvfIlkcXS7IHHzd4F6 NIizSFc4OiCqcoO= Mne2R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gPU4yQSEQvF2u MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR2MEKzN{c,OTh2NECyN|M9N2F-
HT1080 M{DDTmN6fG:2b4jpZ4l1gSCjc4PhfS=> NW\1XHZQPzJiaILz MXXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWFExQDBiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFkvPDVizszNMi=> NYixcpdwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0OFAzOzNpPkG4OFQxOjN|PD;hQi=>
HCT116 MVnBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MoP3O|IhcHK| NIXWb4lCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFEyPiClZXzsd{BmgHC{ZYPzbY5oKHB3MzDn[Y5mKGGodHXyJFczKGi{czDifUBxem:uaX\ldoF1cX[nIHHzd4F6NCCLQ{WwJF0hPi5|NjFOwG0v NX\OSJpbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0Olk5ODlpPkG4OFY6QDB7PD;hQi=>
A2780 NFXLNFFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MkXNO|IhcHK| MkTnRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDMke4NEBk\WyuczDlfJBz\XO|aX7nJJA2OyCpZX7lJIFnfGW{IEeyJIhzeyCkeTDwdo9tcW[ncnH0bZZmKGG|c3H5MEBKSzVyIE2gO{4zOSEQvF2u M1zIc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NE[5PFA6Lz5zOES2PVgxQTxxYU6=
COLO205 MUHBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M{H4WVczKGi{cx?= MXvBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IIC1N{Bl\W[rY3nlcpQhcHWvYX6gR29NVzJyNTDj[YxteyCjZoTldkA4OiCqcoOsJGlEPTBiPTCxNU43OyEQvF2u MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR4OUiwPUc,OTh2Nkm4NFk9N2F-
U2OS NFPyS5JCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NYXycnY5PzJiaILz MX7BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFV{T2OgZ4VtdHNiZYjwdoV{e2mwZzDwOVMh\2WwZTDh[pRmeiB5MjDodpMh[nlicILvcIln\XKjdHn2[UBie3OjeTygTWM2OCB;IEGzMlE5KM7:TT6= NIS5fZY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES2PVgxQSd-MUi0Olk5ODl:L3G+
PC3 MkHYRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NFy1ZW44OiCqcoO= NUPJVnZqSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOg[ZhxemW|c3nu[{BxPTNiZ3Xu[UBi\nSncjC3NkBpenNiYomgdJJwdGmoZYLheIl3\SCjc4PhfUwhUUN3MDC9JFE{Njd5IN88UU4> MmL4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2Nkm4NFkoRjF6NE[5PFA6RC:jPh?=
HCT15 M3qzTWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M4r2NVczKGi{cx?= NH35XnVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFE2KGOnbHzzJIV5eHKnc4PpcocheDV|IHflcoUh[W[2ZYKgO|IhcHK|IHL5JJBzd2yrZnXyZZRqfmViYYPzZZktKEmFNUCgQUAyQC5{NDFOwG0v M{C2RlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NE[5PFA6Lz5zOES2PVgxQTxxYU6=
SW480 M1\TUGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NWXqNFQ3PzJiaILz NEj0NmdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JJA2OyCmZX\pZ4lmdnRiaIXtZY4hW1d2OECgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KHC{b3zp[oVz[XSrdnWgZZN{[XluIFnDOVAhRSB{Nj6yOkDPxE1w M{ntb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NE[5PFA6Lz5zOES2PVgxQTxxYU6=
MCF7 NVTBZmNySW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MUG3NkBpenN? MlzhRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHX4dJJme3OrbnegdFU{KGenbnWgZYZ1\XJiN{KgbJJ{KGK7IIDyc4xq\mW{YYTpeoUh[XO|YYmsJGlEPTBiPTCyOk43PyEQvF2u MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR4OUiwPUc,OTh2Nkm4NFk9N2F-
HCT116/E6 NEfUfnFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M2nYRlczKGi{cx?= MYnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IIC1N{Bl\W[rY3nlcpQhcHWvYX6gTGNVOTF4L1W2JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCycn;sbYZmemG2aY\lJIF{e2G7LDDJR|UxKD1iMkiuPVEh|ryPLh?= M1yweFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NE[5PFA6Lz5zOES2PVgxQTxxYU6=
A2780/E6 NV7vc486SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MUS3NkBpenN? MkSzRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDwOVMh\GWoaXPp[Y51KGi3bXHuJGEzPzhyL1W2JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCycn;sbYZmemG2aY\lJIF{e2G7LDDJR|UxKD1iM{iuOlch|ryPLh?= MoLVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2Nkm4NFkoRjF6NE[5PFA6RC:jPh?=
HL60 MUnBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MVKzJIRigXN? NWTZTWJLSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIUFYxKGOnbHzzJIFnfGW{IEOg[IF6eyCkeTD0dplx[W5iYnz1[UB{fGGrbnnu[{whT0l3MDC9JFMvQCEQvF2u MnT6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2OUG4OlYoRjF6NEmxPFY3RC:jPh?=
HT29 NF\u[5pEgXSxdH;4bYNqfHliYYPzZZk> NIrWNZpEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXDJ7IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuOkDPxE1w MknSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4ME[1OFYoRjF6NkC2OVQ3RC:jPh?=
Hep3B NYrCNYViS3m2b4TvfIlkcXS7IHHzd4F6 M2j3bGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeDOEIHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuOkDPxE1w NHXZeGs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOE[wOlU1Pid-MUi2NFY2PDZ:L3G+
MCF7 MoLmR5l1d3SxeHnjbZR6KGG|c3H5 MkL6R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzLkWg{txONg>? Mk\zQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4ME[1OFYoRjF6NkC2OVQ3RC:jPh?=
A549 NHXIbItEgXSxdH;4bYNqfHliYYPzZZk> M2TxW2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz6xJO69VS5? MkHzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4ME[1OFYoRjF6NkC2OVQ3RC:jPh?=
HaCaT NHnWUVZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGH6RmI4OiCqcoO= M{m0cWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGhiS2GWIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjRizszNMi=> MkD4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4NEC3OFYoRjF6NkSwO|Q3RC:jPh?=
H460 NXnB[ng{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnHMO|IhcHK| MkDsS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTFQ3OCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNkDPxE1w Mor1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4NEC3OFYoRjF6NkSwO|Q3RC:jPh?=
HeLa NEPmcGJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUi3NkBpenN? Mor6S5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOEDPxE1w M2LvXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NkSwO|Q3Lz5zOE[0NFc1PjxxYU6=
SW620 MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX\i[2NNPzJiaILz NWLnTo5zT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hW1d4MkCgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDlizszNMi=> NF63VnY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOE[0NFc1Pid-MUi2OFA4PDZ:L3G+
MIAPaCa2 NXXLdXNrT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXHlN2s1PzJiaILz MYXHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDNTWFR[UOjMjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTBizszNMi=> MoHNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4NEC3OFYoRjF6NkSwO|Q3RC:jPh?=
MCF7 NI[2[|JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmnVO|IhcHK| MkKxS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUh|ryPLh?= M{XibVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NkSwO|Q3Lz5zOE[0NFc1PjxxYU6=
B16 NE[5e5pEgXSxdH;4bYNqfHliYYPzZZk> NHrtd2dEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBDOTZiY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iOD63N{DPxE1w MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZ2NEexPEc,OTh4NES3NVg9N2F-
A549 M2DjS2N6fG:2b4jpZ4l1gSCjc4PhfS=> NWTUUWFlS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNE45PSEQvF2u MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZ2NEexPEc,OTh4NES3NVg9N2F-
SW480 NWnRN2Q6S3m2b4TvfIlkcXS7IHHzd4F6 NFjaNYJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUXzR6MDDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxN{4yPiEQvF2u NX;WblVYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi2OFQ4OThpPkG4OlQ1PzF6PD;hQi=>
BEL-7402 NV3uUlV4S3m2b4TvfIlkcXS7IHHzd4F6 NXfTVWhVS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSkWOLUe0NFIh[2WubIOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTRwNEGg{txONg>? NFLrXlU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOE[0OFcyQCd-MUi2OFQ4OTh:L3G+
BGC-7901 MX\DfZRwfG:6aXPpeJkh[XO|YYm= NHva[5ZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBDT0NvN{mwNUBk\WyuczDifUBOXFRiYYPzZZktKEmFNUCgQUAyPi5|NTFOwG0v Mn\JQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4NES3NVgoRjF6NkS0O|E5RC:jPh?=
HL60 M4PEbWN6fG:2b4jpZ4l1gSCjc4PhfS=> NYfvfY46S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEx4MDDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyNU4{QCEQvF2u Moq3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4NES3NVgoRjF6NkS0O|E5RC:jPh?=
3T3 MXPDfZRwfG:6aXPpeJkh[XO|YYm= MlPNOFghcHK| Mlf6R5l1d3SxeHnjbZR6KGGpYXnud5QhSkGOQjDtc5V{\SB|VEOgZ4VtdHNiYX\0[ZIhPDhiaILzMEBIUTVyIE2gNU42PCEQvF2u NITEUmk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEe5PFYxQSd-MUi3PVg3ODl:L3G+
H460 MXfDfZRwfG:6aXPpeJkh[XO|YYm= NIDuNYQ1QCCqcoO= MmfmR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTFQ3OCClZXzsd{Bi\nSncjC0PEBpenNuIFfJOVAhRSB2LkGg{txONg>? MoOwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh5OUi2NFkoRjF6N{m4OlA6RC:jPh?=
MCF7 M4q0b2N6fG:2b4jpZ4l1gSCjc4PhfS=> MWe0PEBpenN? MXvDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyxiR1m1NEA:KDZwNTFOwG0v M{nkO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6N{m4OlA6Lz5zOEe5PFYxQTxxYU6=
HT29 MYXDfZRwfG:6aXPpeJkh[XO|YYm= MlS1OFghcHK| NVrXV3FrS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUFR{OTDj[YxteyCjZoTldkA1QCCqcoOsJGdKPTBiPTC4Mlkh|ryPLh?= MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDd7OE[wPUc,OTh5OUi2NFk9N2F-
PC3 MVzDfZRwfG:6aXPpeJkh[XO|YYm= MXu0PEBpenN? M4\ub2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHBEOyClZXzsd{Bi\nSncjC0PEBpenNuIFfJOVAhRSBzND62JO69VS5? M4XuRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6N{m4OlA6Lz5zOEe5PFYxQTxxYU6=
DU145 M2nSTGN6fG:2b4jpZ4l1gSCjc4PhfS=> NXX0N3VYPDhiaILz MkTiR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSHUyPDViY3XscJMh[W[2ZYKgOFghcHK|LDDHTVUxKD1iMUWuOEDPxE1w MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDd7OE[wPUc,OTh5OUi2NFk9N2F-
K562 M3L5OGN6fG:2b4jpZ4l1gSCjc4PhfS=> MVi0PEBpenN? M{m2UGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGs2PjJiY3XscJMh[W[2ZYKgOFghcHK|LDDHTVUxKD1iMU[uO{DPxE1w NIjEWYE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEe5PFYxQSd-MUi3PVg3ODl:L3G+
M14 MnrFR5l1d3SxeHnjbZR6KGG|c3H5 NGLBVJE1QCCqcoO= Mki1R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUVE1KGOnbHzzJIFnfGW{IES4JIhzeyxiR1m1NEA:KDJ{LkSg{txONg>? MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDd7OE[wPUc,OTh5OUi2NFk9N2F-
colon cancer cell M{TwUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkftOFghcHK| MlHxS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gR49td25iY3HuZ4VzKGOnbHzzJIFnfGW{IES4JIhzeyxiR1m1NEA:KDhwM{eg{txONg>? M2fJdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OUWwPVA1Lz5zOEm1NFkxPDxxYU6=
leukemia cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFPWSlk1QCCqcoO= MWTHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDs[ZVs\W2rYTDj[YxteyCjZoTldkA1QCCqcoOsJGdKPTBiPTCxOU4xQSEQvF2u MoC3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh7NUC5NFQoRjF6OUWwPVA1RC:jPh?=
prostate cancer cell MVHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEK4Z|k1QCCqcoO= NV3CeZJnT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4heHKxc4TheIUh[2GwY3XyJINmdGy|IHHmeIVzKDR6IHjyd{whT0l3MDC9JFIzNjdizszNMi=> MlzjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh7NUC5NFQoRjF6OUWwPVA1RC:jPh?=
renal cancer cell NXTJNGVwT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFPLZZM1QCCqcoO= MoDZS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gdoVv[WxiY3HuZ4VzKGOnbHzzJIFnfGW{IES4JIhzeyxiR1m1NEA:KDR3Lk[g{txONg>? M3HHZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OUWwPVA1Lz5zOEm1NFkxPDxxYU6=
KB M{LibWN6fG:2b4jpZ4l1gSCjc4PhfS=> MojrR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT2Ih[2WubIOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5yMES0OkDPxE1w MoHaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl|NEW1PFEoRjF7M{S1OVgyRC:jPh?=
NCI60 NXj6bJJWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmjUS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUmNKPjBiY3XscJMtKEeLNUCgQUAyPy55IN88UU4> NF7jdFg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUO5PFM{PCd-MUmzPVg{OzR:L3G+
A549 NXrLV4hoS3m2b4TvfIlkcXS7IHHzd4F6 Mof2R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{BjgSCVUlKgcYV1cG:mLDDJR|UxKD1iMkCuPEDPxE1w NF[zNVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUSyNlIxOyd-MUm0NlIzODN:L3G+
PC3 NGHWTplCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M4LaPVQ5KGi{cx?= NH\PeWpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGDDN{Bk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD6wNVYh|ryPLh?= MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTR{M{G5PEc,OTl2MkOxPVg9N2F-
A431 M17FbGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 Mnz3OFghcHK| NHLyb3lCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG0N|Eh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuNFE5KM7:TT6= MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTR{M{G5PEc,OTl2MkOxPVg9N2F-
MCF7 M2T1XmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M121[lI1KGi{cx?= MmW2RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDJ2IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB2LkOg{txONg>? NHnUZYg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUW2NFg1Oid-MUm1OlA5PDJ:L3G+
Bel7402 MXXBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M3r0fVI1KGi{cx?= MUXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEKnbEe0NFIh[2WubIOgZYZ1\XJiMkSgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IESuO{DPxE1w NW\MWplVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm1OlA5PDJpPkG5OVYxQDR{PD;hQi=>
HeLa NFn4dIZEgXSxdH;4bYNqfHliYYPzZZk> MUK0PEBpenN? M1zmZWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhT0l3MDC9JFExKM7:TT6= NGXkOYU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUW3NlYyOyd-MUm1O|I3OTN:L3G+
MCF7 NUjvdZVCS3m2b4TvfIlkcXS7IHHzd4F6 M2HqZlQ5KGi{cx?= NIrjO3lEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEeLNUCgQUAyPSEQvF2u M3jXO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7NUeyOlE{Lz5zOUW3NlYyOzxxYU6=
HeLa M1npUWN6fG:2b4jpZ4l1gSCjc4PhfS=> NG[xUIQ1QCCqcoO= MUPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNEDPxE1w MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTZzOEmyNEc,OTl4MUi5NlA9N2F-
MCF7 M3X2NGN6fG:2b4jpZ4l1gSCjc4PhfS=> NUXiRmlEPDhiaILz MXHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOUDPxE1w NU\2c2xCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm2NVg6OjBpPkG5OlE5QTJyPD;hQi=>
SW1573 NVnYOJRHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MX[0PEBpenN? MUjHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDTW|E2PzNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB2LkGg{txONg>? NHvWOGE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOU[2OFk{OCd-MUm2OlQ6OzB:L3G+
A2780 NWOyZnF{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3fvRVQ5KGi{cx?= NEj3UldIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBCOjd6MDDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IESuOEDPxE1w NWjvUmFXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm2OlQ6OzBpPkG5OlY1QTNyPD;hQi=>
HBL100 M3HhXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NInSTlI1QCCqcoO= Mln2S5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTGJNOTByIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iNT61JO69VS5? MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTZ4NEmzNEc,OTl4NkS5N|A9N2F-
HeLa MonSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NI\H[5I1QCCqcoO= NYjpTGdIT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hUGWOYTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEG5JO69VS5? NHOxW5k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOU[2OFk{OCd-MUm2OlQ6OzB:L3G+
T47D NGDZ[ZpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUfTW|J6PDhiaILz MVvHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDUOFdFKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOjlizszNMi=> NVfVSJlORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm2OlQ6OzBpPkG5OlY1QTNyPD;hQi=>
Colon 26-L5 M37zPGN6fG:2b4jpZ4l1gSCjc4PhfS=> NFXqOJc4OiCqcoO= M1PhRWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KG2xdYPlJGNwdG:wIEK2MWw2KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlQyKM7:TT6= M2TmOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7Nki5NVI2Lz5zOU[4PVEzPTxxYU6=
HeLa NVG1bIxHS3m2b4TvfIlkcXS7IHHzd4F6 NHrrSIM4OiCqcoO= NGnrc3VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjR2IN88UU4> M1fpZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7Nki5NVI2Lz5zOU[4PVEzPTxxYU6=
A549 NXjV[4NjS3m2b4TvfIlkcXS7IHHzd4F6 Mn7kO|IhcHK| M3jJOWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFUvQTFizszNMi=> MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTZ6OUGyOUc,OTl4OEmxNlU9N2F-
B16-BL6 MmLWR5l1d3SxeHnjbZR6KGG|c3H5 NXHSNFBEPzJiaILz NYTTeWliS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhSjF4LVLMOkBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNz6zPUDPxE1w Ml74QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl4OEmxNlUoRjF7Nki5NVI2RC:jPh?=
HT1080 MUDDfZRwfG:6aXPpeJkh[XO|YYm= NFz1[Yo4OiCqcoO= NG[2UphEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXDFyOECgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDhwNUig{txONg>? NGHFVHM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOU[4PVEzPSd-MUm2PFkyOjV:L3G+
OVCAR-3 MkDyRY51cWOjbnPldkBie3OjeR?= NIKzbY81QCCqcoO= MmrPRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF;WR2FTNTNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkCxOVg2KM7:TT6= MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
SR M3LWc2FvfGmlYX7j[ZIh[XO|YYm= MVm0PEBpenN? NGftfGJCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV3Ih[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAxNjB{M{m5JO69VS5? NFjXUVA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0NFU4PCd-MUm3OFA2PzR:L3G+
RPMI8266 MnvWRY51cWOjbnPldkBie3OjeR?= M{KyXFQ5KGi{cx?= Mm\TRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGLQUWk5OjZ4IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6wOFQ3PyEQvF2u MnHvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEC1O|QoRjF7N{SwOVc1RC:jPh?=
MALME-3M MYXBcpRq[2GwY3XyJIF{e2G7 NGSxTGE1QCCqcoO= NIjaRmFCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWFNVUVvM12gZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCwMlA2OTJ7IN88UU4> MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
HCC2998 MV3BcpRq[2GwY3XyJIF{e2G7 MnyyOFghcHK| MWLBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPDNlk6QCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDBwMEWyOFgh|ryPLh?= NGLFOmc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0NFU4PCd-MUm3OFA2PzR:L3G+
NCI-H460 MlzVRY51cWOjbnPldkBie3OjeR?= NHjINZc1QCCqcoO= NGfnSmpCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUmNKNUh2NkCgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCwMlA2PjJ|IN88UU4> MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
SF539 M3fk[WFvfGmlYX7j[ZIh[XO|YYm= MY[0PEBpenN? NVPCe5lZSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNHPTN7IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6wOlMyKM7:TT6= M4[3VlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SwOVc1Lz5zOUe0NFU4PDxxYU6=
Caki1 NGLnb5BCdnSrY3HuZ4VzKGG|c3H5 MVS0PEBpenN? NGS2[YpCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gR4FscTFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkC3NlQ1KM7:TT6= M1mx[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SwOVc1Lz5zOUe0NFU4PDxxYU6=
MDA-MB-435 NInhZphCdnSrY3HuZ4VzKGG|c3H5 M37sO|Q5KGi{cx?= MXrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTR|NTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuNFczPDRizszNMi=> NHTPSVY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0NFU4PCd-MUm3OFA2PzR:L3G+
MCF7 NGG3[FBCdnSrY3HuZ4VzKGG|c3H5 NFvsXoc1QCCqcoO= NYrBSXBoSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkC3PVQ{KM7:TT6= NW\SSmF5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFA2PzRpPkG5O|QxPTd2PD;hQi=>
HCT15 MXjBcpRq[2GwY3XyJIF{e2G7 NV23dphlPDhiaILz M4PDSmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3QyPSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDBwMUC5OlUh|ryPLh?= M1PFZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SwOVc1Lz5zOUe0NFU4PDxxYU6=
COLO205 MVHBcpRq[2GwY3XyJIF{e2G7 M32ydVQ5KGi{cx?= MYXBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1;MU|IxPSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDBwMUW4OFkh|ryPLh?= NVO1bINlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFA2PzRpPkG5O|QxPTd2PD;hQi=>
NCI-H322M M2roemFvfGmlYX7j[ZIh[XO|YYm= MkDCOFghcHK| MUXBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWg{OjKPIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6xO|c5OyEQvF2u MmPVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEC1O|QoRjF7N{SwOVc1RC:jPh?=
HT-29 MYHBcpRq[2GwY3XyJIF{e2G7 NUHpWYlPPDhiaILz NUW0c2ZjSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhVNTJ7IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6xO|c5OyEQvF2u MnLBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEC1O|QoRjF7N{SwOVc1RC:jPh?=
A549 NGjCTGxCdnSrY3HuZ4VzKGG|c3H5 NEfmXmM1QCCqcoO= MmXSRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAxNjF7MEW1JO69VS5? Mo[0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEC1O|QoRjF7N{SwOVc1RC:jPh?=
KM12 NGfrOYdCdnSrY3HuZ4VzKGG|c3H5 NX;MS5gxPDhiaILz MnTORY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFvNNVIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAxNjJzM{ig{txONg>? M{joN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SwOVc1Lz5zOUe0NFU4PDxxYU6=
HCT116 NVu2UJBtSW62aXPhcoNmeiCjc4PhfS=> NYHvXWNJPDhiaILz M3PqZmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkKyPVA6KM7:TT6= MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
SF295 MWPBcpRq[2GwY3XyJIF{e2G7 MV60PEBpenN? NVnwZ21DSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNHOjl3IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6yNlkxQSEQvF2u NV7W[|ZxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFA2PzRpPkG5O|QxPTd2PD;hQi=>
LOXIMVI MkPVRY51cWOjbnPldkBie3OjeR?= MVm0PEBpenN? MYrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTF;YTW1XUSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDBwMkS1OFch|ryPLh?= M2D0bVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SwOVc1Lz5zOUe0NFU4PDxxYU6=
ACHN NIfUUZRCdnSrY3HuZ4VzKGG|c3H5 NFPIZYM1QCCqcoO= Mk\SRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFHDTG4h[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAxNjJ7NUGyJO69VS5? MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
NCI/ADR-RES MV\BcpRq[2GwY3XyJIF{e2G7 MnG0OFghcHK| NYLiNVc1SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG5EUS:DRGKtVmVUKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOC5|MU[yN{DPxE1w MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
NCI-H23 MYLBcpRq[2GwY3XyJIF{e2G7 NIXWemk1QCCqcoO= NWTkb5RpSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KMkOgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCwMlM{OTF|IN88UU4> M3v5TVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SwOVc1Lz5zOUe0NFU4PDxxYU6=
MOLT4 MX\BcpRq[2GwY3XyJIF{e2G7 NXi2[HlqPDhiaILz NHK3[pNCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUW9NXDRiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkO1OFgyKM7:TT6= MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
DU145 MUfBcpRq[2GwY3XyJIF{e2G7 NGP6bo81QCCqcoO= MofURY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFTVNVQ2KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOC5|NkOwPEDPxE1w NVuyV4pQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFA2PzRpPkG5O|QxPTd2PD;hQi=>
HOP62 NWnqepozSW62aXPhcoNmeiCjc4PhfS=> NW\YN4F7PDhiaILz NHfQVXRCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTG9RPjJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkO5PFEyKM7:TT6= NHrpTJM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0NFU4PCd-MUm3OFA2PzR:L3G+
A498 NIHtNXFCdnSrY3HuZ4VzKGG|c3H5 MXy0PEBpenN? M2WwRmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOFk5KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOC5|OUixNUDPxE1w NILlTpQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0NFU4PCd-MUm3OFA2PzR:L3G+
SK-MEL-5 M2fi[WFvfGmlYX7j[ZIh[XO|YYm= M2jXfVQ5KGi{cx?= MXjBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU1utUWVNNTViY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkS2O|c1KM7:TT6= MkP4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEC1O|QoRjF7N{SwOVc1RC:jPh?=
SN12C MU\BcpRq[2GwY3XyJIF{e2G7 M3j4WFQ5KGi{cx?= MXrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU16xNmMh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAxNjVyMUG5JO69VS5? NWXaT5psRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFA2PzRpPkG5O|QxPTd2PD;hQi=>
UACC62 NXj6WHdOSW62aXPhcoNmeiCjc4PhfS=> NY\iVnJXPDhiaILz NYOwfGx3SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHVCS0N4MjDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuOVI1QDFizszNMi=> M3nvVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SwOVc1Lz5zOUe0NFU4PDxxYU6=
786-0 NGL2TY1CdnSrY3HuZ4VzKGG|c3H5 M2rRSlQ5KGi{cx?= MlX6RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIEe4Ok0xKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOC55MkS0OEDPxE1w Mn7pQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEC1O|QoRjF7N{SwOVc1RC:jPh?=
U251 M1zkTWFvfGmlYX7j[ZIh[XO|YYm= NWPKZVBbPDhiaILz MUHBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iVUK1NUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFAvQTF{MEGg{txONg>? MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
SW620 MnWwRY51cWOjbnPldkBie3OjeR?= Mnv2OFghcHK| NHzyNllCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV3c3OjBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkmzN|I2KM7:TT6= MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
M14 NV2xb5pJSW62aXPhcoNmeiCjc4PhfS=> M1:4U|Q5KGi{cx?= MljyRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF2xOEBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFAvQTd5MkSg{txONg>? M{HWblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SwOVc1Lz5zOUe0NFU4PDxxYU6=
SK-MEL-28 MkCzRY51cWOjbnPldkBie3OjeR?= MUO0PEBpenN? MmnERY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPLMW1GVC1{ODDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEGuNFI{OjlizszNMi=> M33qUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SwOVc1Lz5zOUe0NFU4PDxxYU6=
TK10 NGXZbJdCdnSrY3HuZ4VzKGG|c3H5 NF;2[mc1QCCqcoO= NHr0S4pCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWGsyOCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDFwMUKyNFIh|ryPLh?= MmrHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEC1O|QoRjF7N{SwOVc1RC:jPh?=
IGROV1 MXzBcpRq[2GwY3XyJIF{e2G7 M1;3[|Q5KGi{cx?= NEjtSIpCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTWdTV1ZzIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMT6yN|AzPyEQvF2u MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
UO31 M17uTGFvfGmlYX7j[ZIh[XO|YYm= MWK0PEBpenN? MmPtRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGXPN|Eh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAyNjRzMkW0JO69VS5? NYjaTJlyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFA2PzRpPkG5O|QxPTd2PD;hQi=>
SF268 NXzRR|ZpSW62aXPhcoNmeiCjc4PhfS=> MX[0PEBpenN? NFSwZlJCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2YzPjhiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSBzLkW4OFg6KM7:TT6= NHvSWoM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0NFU4PCd-MUm3OFA2PzR:L3G+
OVCAR8 NEX2WotCdnSrY3HuZ4VzKGG|c3H5 NXzRbHNPPDhiaILz MWfBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iT2\DRXI5KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOS55M{e4JO69VS5? NF;mT2w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0NFU4PCd-MUm3OFA2PzR:L3G+
HL-60(TB) M2K4WmFvfGmlYX7j[ZIh[XO|YYm= M2OzdlQ5KGi{cx?= MVLBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFytOlApXEJrIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMj6yPVA5PyEQvF2u Mn3RQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEC1O|QoRjF7N{SwOVc1RC:jPh?=
PC3 NH60NmVCdnSrY3HuZ4VzKGG|c3H5 MYm0PEBpenN? MYPBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUFOzJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNk4{PDR{MzFOwG0v MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
RXF393 MUjBcpRq[2GwY3XyJIF{e2G7 NYPXNIRHPDhiaILz M{L5RWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDSXGY{QTNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB{Lk[zNFI4KM7:TT6= NHu5VGo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0NFU4PCd-MUm3OFA2PzR:L3G+
K562 NUe0PIRXSW62aXPhcoNmeiCjc4PhfS=> MUG0PEBpenN? Mn\BRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFu1OlIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUA{NjV2OEGzJO69VS5? NXfYOIZYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFA2PzRpPkG5O|QxPTd2PD;hQi=>
UACC257 M2T5WmFvfGmlYX7j[ZIh[XO|YYm= MUW0PEBpenN? NIT4eYxCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWWFESzJ3NzDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEOuOVQ5OTNizszNMi=> NYmwOlRpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFA2PzRpPkG5O|QxPTd2PD;hQi=>
SNB19 MmDERY51cWOjbnPldkBie3OjeR?= M2TlR|Q5KGi{cx?= M3u3OWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTUmIyQSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDNwOECxPFkh|ryPLh?= MoriQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEC1O|QoRjF7N{SwOVc1RC:jPh?=
OVCAR4 M1:5cGFvfGmlYX7j[ZIh[XO|YYm= MWe0PEBpenN? MnzrRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF;WR2FTPCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDRwNE[2PFQh|ryPLh?= MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
MDA-MB-231 MoWzRY51cWOjbnPldkBie3OjeR?= MX[0PEBpenN? MXHBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTJ|MTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IE[uOlA3QTNizszNMi=> MnLUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEC1O|QoRjF7N{SwOVc1RC:jPh?=
NCI-H522 MlT5RY51cWOjbnPldkBie3OjeR?= NYi1bm5nPDhiaILz M3vnPWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kuUDV{MjDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEeuNlQ1OzZizszNMi=> NEW4fmQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0NFU4PCd-MUm3OFA2PzR:L3G+
T47D MY\BcpRq[2GwY3XyJIF{e2G7 NX3QSY9YPDhiaILz MX\BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iVES3SEBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFgvOTJ6M{Gg{txONg>? M4nuR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SwOVc1Lz5zOUe0NFU4PDxxYU6=
CCRF-CEM M{XJUWFvfGmlYX7j[ZIh[XO|YYm= NEf4bIw1QCCqcoO= M37CeGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDR3JHNUOHTTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEmuO|czOzdizszNMi=> MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
Hs 578T MVjBcpRq[2GwY3XyJIF{e2G7 MoTiOFghcHK| M3Hre2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDId{A2PziWIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iOT63O|I{PyEQvF2u MlnJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEC1O|QoRjF7N{SwOVc1RC:jPh?=
BT549 M3LnNmFvfGmlYX7j[ZIh[XO|YYm= MUW0PEBpenN? MoS4RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFLUOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOTBwN{G1NkDPxE1w MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
OVCAR5 NHfERoVCdnSrY3HuZ4VzKGG|c3H5 MnHzOFghcHK| MlixRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF;WR2FTPSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDFyLkm2OFgh|ryPLh?= NIT6SIM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0NFU4PCd-MUm3OFA2PzR:L3G+
SKOV3 MkLaRY51cWOjbnPldkBie3OjeR?= MX20PEBpenN? NYe5WmtLSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNMV1Z|IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMkGuPFc4PiEQvF2u MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2MEW3OEc,OTl5NEC1O|Q9N2F-
MCF7 NXvpcplRS3m2b4TvfIlkcXS7IHHzd4F6 NWPoXno5PzJiaILz NIfjPG1EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjNizszNMi=> NIT3fJI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0N|g3Oyd-MUm3OFM5PjN:L3G+
T47D NF7IV45CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MXO3NkBpenN? NV:ydItGSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDUOFdFKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlYh|ryPLh?= M{GwNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SzPFY{Lz5zOUe0N|g3OzxxYU6=
MES-SA Mln6RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NXy4[|d[PzJiaILz MXTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2HUz3TRUBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMT6xJO69VS5? NIDrNZU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0N|g3Oyd-MUm3OFM5PjN:L3G+
SW480 NVLBc3ZzSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NFXsS484OiCqcoO= MnXQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVV{S4NEBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMj6xJO69VS5? M3\3TFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SzPFY{Lz5zOUe0N|g3OzxxYU6=
HCT116 NGDLTopCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M1rOeFczKGi{cx?= NVTkZ4hzSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIvPiEQvF2u NHGzZZQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0N|g3Oyd-MUm3OFM5PjN:L3G+
UACC-812 M3vsRWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M33J[VczKGi{cx?= MX3BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFWDQ1OtPFEzKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlEh|ryPLh?= NXrNNG1FRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFM5PjNpPkG5O|Q{QDZ|PD;hQi=>
RL MVnBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NXXZXnRZPzJiaILz NET3fnNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGLMJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|LkKg{txONg>? Mm\RQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEO4OlMoRjF7N{SzPFY{RC:jPh?=
SW48 NWrRdohsSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NF:3XVU4OiCqcoO= NV\ST2V[SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|Q5KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0MlQh|ryPLh?= NYXtfJZORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFM5PjNpPkG5O|Q{QDZ|PD;hQi=>
HeLa M3W4ZWN6fG:2b4jpZ4l1gSCjc4PhfS=> M3rUZVQ5KGi{cx?= MonKR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVAh|ryPLh?= MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd7NUi0N{c,OTl5OUW4OFM9N2F-
MCF7 M4\OfGN6fG:2b4jpZ4l1gSCjc4PhfS=> M37pTlQ5KGi{cx?= NFXXPYFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPSEQvF2u NUDiVVhtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3PVU5PDNpPkG5O|k2QDR|PD;hQi=>
KB MYrDfZRwfG:6aXPpeJkh[XO|YYm= NEXqZWI4OiCqcoO= MVLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLRkBk\WyuczDh[pRmeiB5MjDodpMhVVSWIHHzd4F6NCCLQ{WwJF0hOTJwNTFOwG0v MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTh2NkOwNkc,OTl6NE[zNFI9N2F-
HT1080 MnjyR5l1d3SxeHnjbZR6KGG|c3H5 MmHPO|IhcHK| NIX0RlJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXDFyOECgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDVwMjFOwG0v MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTlzOUC1Nkc,OTl7MUmwOVI9N2F-
HeLa M4C0UGN6fG:2b4jpZ4l1gSCjc4PhfS=> MkjLOFghcHK| NFqxfFVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOCEQvF2u M3PITFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUG5NFY2Lz5zOUmxPVA3PTxxYU6=
MCF7 MXTDfZRwfG:6aXPpeJkh[XO|YYm= NXL0dlN2PDhiaILz MnvHR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUh|ryPLh?= NYDuXpdDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5NVkxPjVpPkG5PVE6ODZ3PD;hQi=>
COLO205 MoHuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4rC[lQ5KGi{cx?= MmqxS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gR29NVzJyNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygTWM2OCB;IEKxJO69VS5? MojIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7M{m1NlIoRjF7OUO5OVIzRC:jPh?=
HCT116 M4TZXWN6fG:2b4jpZ4l1gSCjc4PhfS=> NEn6VYwzPCCqcoO= NGPQd5ZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzMU[gZ4VtdHNiYX\0[ZIhOjRiaILzJIJ6KHS{eYDhckBjdHWnIHX4Z4x2e2mxbjDhd5NigSxiSVO1NEA:KDNwMEOg{txONg>? NWfzT3l4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCxOlM5QTVpPkKwNVY{QDl3PD;hQi=>
MOLT4 NX3uUnJ[SW62aYT1cY9zKGG|c3H5 NVHzSHRjOjRiaILz MV7BcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPT1zUOEBk\WyuczDh[pRmeiB{NDDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD6wN{DPxE1w NV2wcoRvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCyNVE2PjRpPkKwNlEyPTZ2PD;hQi=>
H460 M3\jS2FvfGm2dX3vdkBie3OjeR?= NGnEU4QzPCCqcoO= MmHlRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSES2NEBk\WyuczDh[pRmeiB{NDDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMjFOwG0v MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODJzMUW2OEc,OjB{MUG1OlQ9N2F-
HCT116 NIXj[GdCdnSrdIXtc5Ih[XO|YYm= MV2yOEBpenN? MXLBcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZYZ1\XJiMkSgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IESg{txONg>? NHKzeGg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEKxNVU3PCd-MkCyNVE2PjR:L3G+
SW620 MVHBcpRqfHWvb4KgZZN{[Xl? M{K2[VI1KGi{cx?= NHHy[o1CdnSrdIXtc5Ih[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|YzOCClZXzsd{Bi\nSncjCyOEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gPUDPxE1w NYHFdok{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCyNVE2PjRpPkKwNlEyPTZ2PD;hQi=>
MCF7 MnTlRY51cXS3bX;yJIF{e2G7 NIPpUJUzPCCqcoO= M2nufmFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlch[2WubIOgZYZ1\XJiMkSgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG1JO69VS5? MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODJzMUW2OEc,OjB{MUG1OlQ9N2F-
colon cancer NIrK[olCdnSrdIXtc5Ih[XO|YYm= MnzaOFghcHK| NUO3NHVqSW62aYT1cY9zKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gZ49td25iY3HuZ4VzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGdKPTBiPTC4MlQh|ryPLh?= MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODN3MEixNUc,OjB|NUC4NVE9N2F-
leukemia M3rVdGFvfGm2dX3vdkBie3OjeR?= MXu0PEBpenN? M2TBUWFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIHzleYtmdWmjIHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEeLNUCgQUAyPS5zIN88UU4> M1fC[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyM{WwPFEyLz5{MEO1NFgyOTxxYU6=
prostate cancer M3rRN2FvfGm2dX3vdkBie3OjeR?= MXO0PEBpenN? MkjBRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5icILvd5RifGViY3HuZ4VzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGdKPTBiPTCyNk44KM7:TT6= NVPPemhPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCzOVA5OTFpPkKwN|UxQDFzPD;hQi=>
renal cancer MXrBcpRqfHWvb4KgZZN{[Xl? M1WzbVQ5KGi{cx?= M{PCTmFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIILlcoFtKGOjbnPldkBk\WyuczDh[pRmeiB2ODDodpMh[nliU2LCJIF{e2G7LDDHTVUxKD1iNEWuOkDPxE1w M2[0SVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyM{WwPFEyLz5{MEO1NFgyOTxxYU6=
KB MXPDfZRwfG:6aXPpeJkh[XO|YYm= NIKwb3M{KGSjeYO= MX;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLRkBk\WyuczDh[pRmeiB|IHThfZMh[nliTWTUJIF{e2G7LDDJR|UxKD1iND60OkDPxE1w MoLRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB|NU[2OVUoRjJyM{W2OlU2RC:jPh?=
NCI-H460 NYTCfpRTS3m2b4TvfIlkcXS7IHHzd4F6 MlOwR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUmNKNUh2NkCgZ4VtdHNuIFfJOVAhRSB{LkOg{txONg>? MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODN3Nke1Nkc,OjB|NU[3OVI9N2F-
3T3 NHzEdItEgXSxdH;4bYNqfHliYYPzZZk> M1;yUGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEKDTFKgcY92e2ViM2SzJINmdGy|LDDHTVUxKD1iMzFOwG0v MmCyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB|NU[3OVIoRjJyM{W2O|UzRC:jPh?=
MCF7 MmrDR5l1d3SxeHnjbZR6KGG|c3H5 NVXpfoNxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyxiR1m1NEA:KDRwNTFOwG0v NHnFeoc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEO1Olc2Oid-MkCzOVY4PTJ:L3G+
DU145 MofpR5l1d3SxeHnjbZR6KGG|c3H5 M3fyfGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGRWOTR3IHPlcIx{NCCJSUWwJF0hPS5|IN88UU4> MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODN3Nke1Nkc,OjB|NU[3OVI9N2F-
HT-29 NYfRSHJ2S3m2b4TvfIlkcXS7IHHzd4F6 MmXlR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQuOjliY3XscJMtKEeLNUCgQUAyPC57IN88UU4> NYLieVJ{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCzOVY4PTJpPkKwN|U3PzV{PD;hQi=>
M14 M3\oeGN6fG:2b4jpZ4l1gSCjc4PhfS=> NV3V[oE3S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVTF2IHPlcIx{NCCJSUWwJF0hOzJwNDFOwG0v NGfhd3o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEO1Olc2Oid-MkCzOVY4PTJ:L3G+
SFME M324WmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MmOzNlQhcHK| Mn\ZRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDtc5V{\SCVRl3FJINmdGy|IHHmeIVzKDJ2IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|LkKg{txONg>? NVn2UIhTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCzPVg6PzJpPkKwN|k5QTd{PD;hQi=>
r/m HM-SFME-1 NYfBdWFbSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MYSyOEBpenN? Ml3NRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDtc5V{\SC{L32gTG0uW0[PRT2xJINmdGy|IHHmeIVzKDJ2IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB2OD61JO69VS5? M{LJ[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyM{m4PVczLz5{MEO5PFk4OjxxYU6=
H460 M33IU2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NIThbIczPCCqcoO= M3vHVmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSES2NEBk\WyuczDh[pRmeiB{NDDodpMh[nlidIL5dIFvKGKudXWg[ZhkdHW|aX;uJIF{e2G7LDDJR|UxKD1iMj63JO69VS5? M2Kzd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyNECzO|AyLz5{MESwN|cxOTxxYU6=
MDA231 NH3YRnRCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NI\VRVIzPCCqcoO= MorERY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPRFGyN|Eh[2WubIOgZYZ1\XJiMkSgbJJ{KGK7IITyfZBidiCkbIXlJIV5[2y3c3nvckBie3OjeTygTWM2OCB;IEOuOUDPxE1w MnHiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB2MEO3NFEoRjJyNECzO|AyRC:jPh?=
A549 M2n4fGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NVL1cZoyOjRiaILz NWnXSG96SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IEK0JIhzeyCkeTD0dplx[W5iYnz1[UBmgGOudYPpc44h[XO|YYmsJGlEPTBiPTC1MlQh|ryPLh?= MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODRyM{ewNUc,OjB2MEO3NFE9N2F-
MCF7 MkXwRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MVSyOEBpenN? NV;VTWNnSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEK0JIhzeyCkeTD0dplx[W5iYnz1[UBmgGOudYPpc44h[XO|YYmsJGlEPTBiPTCxOU4zKM7:TT6= NHTVZZY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MESwN|cxOSd-MkC0NFM4ODF:L3G+
HeLa NUK2ZWZSS3m2b4TvfIlkcXS7IHHzd4F6 NVn5XpVuPDhiaILz M36zbmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFExKM7:TT6= M4Xn[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyNEC1PFgyLz5{MESwOVg5OTxxYU6=
SKBR3 M2P2N2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 M2\PNFQ5KGi{cx?= NUjPbpR{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBme3S{b3flckBz\WOncITvdkBl\W[rY3nlcpQhcHWvYX6gV2tDWjNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFMh|ryPLh?= Mof0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB2M{iwPVIoRjJyNEO4NFkzRC:jPh?=
MCF7/BUS MVzBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NEnlNmI1QCCqcoO= NGiz[29CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlcwSlWVIHPlcIx{KGW6cILld5NqdmdiZYP0do9o\W5icnXj[ZB1d3JiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiR1m1NEA:KDZwMjFOwG0v NXvjWlczRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0N|gxQTJpPkKwOFM5ODl{PD;hQi=>
MCF7 Ml\KRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NGXRVXg1QCCqcoO= MYnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiZYjwdoV{e2mwZzDld5Rzd2enbjDy[YNmeHSxcjDh[pRmeiB2ODDodpMh[nliU2LCJIF{e2G7LDDHTVUxKD1iOD6zJO69VS5? M2faWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyNEO4NFkzLz5{MESzPFA6OjxxYU6=
T47D MW\BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MYC0PEBpenN? NX:xPGd7SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDUOFdFKGOnbHzzJIV5eHKnc4Ppcoch\XO2cn;n[Y4hemWlZYD0c5Ih[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFQ4KM7:TT6= NXvvVFEyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0N|gxQTJpPkKwOFM5ODl{PD;hQi=>
HCT116 NY\iOXdDS3m2b4TvfIlkcXS7IHHzd4F6 Mnq5O|IhcHK| M2DBSmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDFzNjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOS57MzFOwG0v NUDCenVlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0PVQ1QTJpPkKwOFk1PDl{PD;hQi=>
DU145 M2LHbWN6fG:2b4jpZ4l1gSCjc4PhfS=> NFrJfmg4OiCqcoO= Mly1R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSHUyPDViY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIvOTlizszNMi=> M{f4RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyNEm0OFkzLz5{MES5OFQ6OjxxYU6=
SGC7901 M1rp[WN6fG:2b4jpZ4l1gSCjc4PhfS=> MXK3NkBpenN? M4rOUmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNISzd7MEGgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJwOUWg{txONg>? MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODR7NES5Nkc,OjB2OUS0PVI9N2F-
HeLa Ml3IR5l1d3SxeHnjbZR6KGG|c3H5 MkLWO|IhcHK| NUL3fJdYS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hQS55IN88UU4> NWK1dmlvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0PVQ1QTJpPkKwOFk1PDl{PD;hQi=>
K562 NYPZOmtmS3m2b4TvfIlkcXS7IHHzd4F6 Mny5O|IhcHK| MmPuR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT|U3OiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOFUvPCEQvF2u NUjRb4ZxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0PVQ1QTJpPkKwOFk1PDl{PD;hQi=>
OVCAR-3 NGC4c4ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYf2[nBUPDhiaILz M2rYXGdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG9XS0GULUOgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCwMlAyPTh3IN88UU4> MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
SR MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUK1[2NTPDhiaILz NV3LXZZHT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hW1JiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkCyN|k6KM7:TT6= NF\VTlA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
RPMI8266 MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYq0PEBpenN? NEmwdXhIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBTWE2LOEK2OkBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFAvODR2Nkeg{txONg>? NILGRW89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
MALME-3M NWLX[2JUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWeyXZJOPDhiaILz NU[3R29nT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hVUGOTVWtN20h[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAxNjB3MUK5JO69VS5? MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
HCC2998 MnXGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MX20PEBpenN? MYLHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDIR2MzQTl6IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6wOVI1QCEQvF2u NV7uToVbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
NCI-H460 M3HRZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEHWNYE1QCCqcoO= M2naWmdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNE[wJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNE4xPTZ{MzFOwG0v NFfxb2Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
SF539 M1\DPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MV60PEBpenN? NVLPOJZpT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hW0Z3M{mgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCwMlA3OzFizszNMi=> NWTHRoZQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
Caki1 NIjmTFNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2XaRVQ5KGi{cx?= M3nwT2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGNic2lzIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6wO|I1PCEQvF2u MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
MDA-MB-435 NVTJPHFwT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUi0PEBpenN? NHHGRpBIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBOTEFvTVKtOFM2KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOC5yN{K0OEDPxE1w MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
MCF7 M{HsPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXy0PEBpenN? NXOxXGg1T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hVUOINzDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuNFc6PDNizszNMi=> MlzmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUCyNFQoRjJyOEWwNlA1RC:jPh?=
HCT15 M1XVVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NETMemM1QCCqcoO= NEHlS25Iem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBJS1RzNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuNVA6PjVizszNMi=> M1y4SFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOEWwNlA1Lz5{MEi1NFIxPDxxYU6=
COLO205 M4jwNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEWzd5k1QCCqcoO= NELrW|BIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBEV0yRMkC1JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNE4yPTh2OTFOwG0v NWP3T4xKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
HT-29 NHjMVHNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVG0PEBpenN? MnO1S5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTHQuOjliY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkG3O|g{KM7:TT6= NVHMdmp[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
NCI-H322M NW\YXWxPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoPYOFghcHK| MVvHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDOR2kuUDN{Ml2gZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCwMlE4Pzh|IN88UU4> NWLwcVk3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
A549 MorKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmT5OFghcHK| MVrHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOC5zOUC1OUDPxE1w MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
KM12 MoezS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NE\tTW81QCCqcoO= NFnWUG9Iem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBMVTF{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6yNVM5KM7:TT6= NIDIdZo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
HCT116 MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnvYOFghcHK| MWnHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkKyPVA6KM7:TT6= NVXKSXR5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
SF295 NYm2WndYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4q5eFQ5KGi{cx?= NFjy[3dIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBUTjJ7NTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuNlI6ODlizszNMi=> MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
LOXIMVI M4XnO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWm0PEBpenN? NXrmR24{T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hVE:[SV3WTUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFAvOjR3NEeg{txONg>? MnfFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUCyNFQoRjJyOEWwNlA1RC:jPh?=
ACHN MlnKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUPxZYRUPDhiaILz NFXCUVJIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBCS0iQIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6yPVUyOiEQvF2u NFi2PYU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
NCI/ADR-RES MlfvS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2\KNlQ5KGi{cx?= M372R2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG5EUS:DRGKtVmVUKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOC5|MU[yN{DPxE1w NF3mUGM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
NCI-H23 MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYnobJlOPDhiaILz MYTHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDOR2kuUDJ|IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6zN|EyOyEQvF2u NVXhdY1PRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
MOLT4 MmXPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmLaOFghcHK| MXTHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDNU2xVPCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDBwM{W0PFEh|ryPLh?= NEDnUZE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
DU145 NHXBdmpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYXJPG9qPDhiaILz MkHUS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gSHUyPDViY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkO2N|A5KM7:TT6= NGryTWg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
HOP62 NVjuVpJ2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVTKcIVSPDhiaILz MXHHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDIU3A3OiClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDBwM{m4NVEh|ryPLh?= NGfK[|Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
A498 NWjaTmM1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF7CUG01QCCqcoO= MkjFS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gRVQ6QCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDBwM{m4NVEh|ryPLh?= NGG5c2U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
SK-MEL-5 MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoG3OFghcHK| M1PMO2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJHNMNU2HTD21JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNE41Pjd5NDFOwG0v NWP6UFZjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
SN12C M2TkZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXy0PEBpenN? MXvHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDTUlEzSyClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDBwNUCxNVkh|ryPLh?= MnL6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUCyNFQoRjJyOEWwNlA1RC:jPh?=
UACC62 NWP4RmFDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml;4OFghcHK| M{O4[Gdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJHVCS0N4MjDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuOVI1QDFizszNMi=> M4n3eVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOEWwNlA1Lz5{MEi1NFIxPDxxYU6=
786-0 MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWm0PEBpenN? M3PSR2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJFc5Pi1yIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD63NlQ1PCEQvF2u NETFS|Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
U251 MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXPwUYNjPDhiaILz NHjLe49Iem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBWOjVzIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD65NVIxOSEQvF2u MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
SW620 M3niN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MU[0PEBpenN? M2iycWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJHNYPjJyIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD65N|MzPSEQvF2u NUHOTWl{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
M14 MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX;JN4F1PDhiaILz NFvQWoFIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBOOTRiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkm3O|I1KM7:TT6= Ml\iQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUCyNFQoRjJyOEWwNlA1RC:jPh?=
SK-MEL-28 M1O5dWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1vNWlQ5KGi{cx?= NXeyb2dUT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTVXMMVI5KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOS5yMkOyPUDPxE1w NGrGT2g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
TK10 MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2G5OlQ5KGi{cx?= M3LZVWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJHRMOTBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSBzLkGyNlAzKM7:TT6= NVPVZmFVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
IGROV1 NX\FO2p7T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUm0PEBpenN? MnLnS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTWdTV1ZzIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMT6yN|AzPyEQvF2u MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
UO31 MoS4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NInWSZU1QCCqcoO= Ml33S5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gWW8{OSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDFwNEGyOVQh|ryPLh?= NVm5SnJYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
SF268 M3\3Nmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIi0WJA1QCCqcoO= NIPq[JlIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBUTjJ4ODDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEGuOVg1QDlizszNMi=> MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
OVCAR8 MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4ftcFQ5KGi{cx?= M2TCc2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG9XS0GUODDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEGuO|M4QCEQvF2u MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
HL-60(TB) M3n1NWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYnlZms6PDhiaILz M37pW2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGhNNTZyKGTCLUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFIvOjlyOEeg{txONg>? M1K5NFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOEWwNlA1Lz5{MEi1NFIxPDxxYU6=
PC3 M2O5Tmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWL4O5NmPDhiaILz NI\xU5lIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBRSzNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB{LkO0OFI{KM7:TT6= MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
RXF393 MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX:0PEBpenN? MV;Hdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDSXGY{QTNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB{Lk[zNFI4KM7:TT6= NFG3UnY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
K562 NVLobXdDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXK0PEBpenN? M2OxXGdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGs2PjJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB|LkW0PFE{KM7:TT6= Mmf6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUCyNFQoRjJyOEWwNlA1RC:jPh?=
UACC257 NXHK[pY{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3;PWFQ5KGi{cx?= NEe0bZRIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBWSUOFMkW3JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gN{42PDhzMzFOwG0v MkLBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUCyNFQoRjJyOEWwNlA1RC:jPh?=
SNB19 NHu2fINIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2foU|Q5KGi{cx?= M2LacWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJHNPSjF7IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMz64NFE5QSEQvF2u M1GxOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOEWwNlA1Lz5{MEi1NFIxPDxxYU6=
OVCAR4 MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWW0PEBpenN? M1\qe2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG9XS0GUNDDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IESuOFY3QDRizszNMi=> Mn;rQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUCyNFQoRjJyOEWwNlA1RC:jPh?=
MDA-MB-231 M123O2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVO0PEBpenN? NGHreZNIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBOTEFvTVKtNlMyKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hPi54ME[5N{DPxE1w MnTYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUCyNFQoRjJyOEWwNlA1RC:jPh?=
NCI-H522 NIDnWZBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mn[yOFghcHK| MnPBS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUmNKNUh3MkKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTC3MlI1PDN4IN88UU4> M2XzT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOEWwNlA1Lz5{MEi1NFIxPDxxYU6=
T47D NUDQT4FQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MX20PEBpenN? MVXHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDUOFdFKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hQC5zMkizNUDPxE1w M{HNcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOEWwNlA1Lz5{MEi1NFIxPDxxYU6=
CCRF-CEM MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX60PEBpenN? NHn1[nFIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBES1KILVPFUUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFkvPzd{M{eg{txONg>? Mk\YQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUCyNFQoRjJyOEWwNlA1RC:jPh?=
Hs 578T Ml\OS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1zqVlQ5KGi{cx?= M2DtO2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGh{KDV5OGSgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTC5Mlc4OjN5IN88UU4> NY[wcnQ2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
BT549 M4r2fGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVrRVIdPPDhiaILz MUHHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDCWFU1QSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDFyLkexOVIh|ryPLh?= MkLHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUCyNFQoRjJyOEWwNlA1RC:jPh?=
OVCAR5 NH\BW2RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1e3c|Q5KGi{cx?= MknBS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gU3ZESVJ3IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMUCuPVY1QCEQvF2u NWPz[2pJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
SKOV3 NIeyXlVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MojGOFghcHK| MmnnS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gV2tQXjNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB{MT64O|c3KM7:TT6= NGizWHI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
HCT116 NEDHUGlCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NFPIR3g4OiCqcoO= M2HtVmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPUNVE3KGOnbHzzJIV5eHKnc4PpcocheDV|IHHmeIVzKDd{IHjyd{BjgSClZXzseIl1\XJvZ3zvJIF{e2G7LDDJR|UxKD1iMUKg{txONg>? NUD2ToFERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4O|M4PDBpPkKwPFc{PzRyPD;hQi=>
A2780 Mm\yRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MWC3NkBpenN? NX\JRZB{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBNlc5OCClZXzsd{BmgHC{ZYPzbY5oKHB3MzDh[pRmeiB5MjDodpMh[nliY3XscJRqfGW{LXfsc{Bie3OjeTygTWM2OCB;IEG0JO69VS5? Mn7JQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6N{O3OFAoRjJyOEezO|QxRC:jPh?=
U2OS NWDOc4VISW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NWnKNpFOPzJiaILz MVXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFV{T2OgZ4VtdHNiZYjwdoV{e2mwZzDwOVMh[W[2ZYKgO|IhcHK|IHL5JINmdGy2aYTldk1odG9iYYPzZZktKEmFNUCgQUAyPiEQvF2u M13iRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOEezO|QxLz5{MEi3N|c1ODxxYU6=
p53 deficient PC3 Mm\vRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NUPaTYxFPzJiaILz NVr6fVVTSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDwOVMh\GWoaXPp[Y51KFCFMzDj[YxteyCjZoTldkA4OiCqcoOgZpkh[2WubITpeIVzNWeubzDhd5NigSxiSVO1NEA:KDNyIN88UU4> M{DJRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOEezO|QxLz5{MEi3N|c1ODxxYU6=
SF539 NHHtR2dCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NVj6d3g5PzJiaILz MYjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOINUO5JINmdGy|IHX4dJJme3OrbnegdFU{KGGodHXyJFczKGi{czDifUBk\WyudHn0[ZIu\2yxIHHzd4F6NCCLQ{WwJF0hPDNizszNMi=> NYnLZYxsRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4O|M4PDBpPkKwPFc{PzRyPD;hQi=>
HCT15 Mk\0RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MnTnO|IhcHK| NHzoNXFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFE2KGOnbHzzJIV5eHKnc4PpcocheDV|IHHmeIVzKDd{IHjyd{BjgSClZXzseIl1\XJvZ3zvJIF{e2G7LDDJR|UxKD1iNEig{txONg>? M1i0[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOEezO|QxLz5{MEi3N|c1ODxxYU6=
T3M4 NG[yTFZEgXSxdH;4bYNqfHliYYPzZZk> M13YeWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHQ{VTRiY3XscJMh[nliY4L5d5RidCC4aX;s[ZQhe3SjaX7pcoctKEmFNUCgQUAxNjN|IN88UU4> Ml\aQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB7M{CxNlMoRjJyOUOwNVI{RC:jPh?=
Colo-357 MofNR5l1d3SxeHnjbZR6KGG|c3H5 MWDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDc4xwNTN3NzDj[YxteyCkeTDjdpl{fGGuII\pc4xmfCC|dHHpcolv\yxiSVO1NEA:KDJwMEWg{txONg>? M4\4dlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUOwNVI{Lz5{MEmzNFEzOzxxYU6=
Patu-T NVjjNpg{S3m2b4TvfIlkcXS7IHHzd4F6 MXfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDQZZR2NVRiY3XscJMh[nliY4L5d5RidCC4aX;s[ZQhe3SjaX7pcoctKEmFNUCgQUAzNjB6IN88UU4> NIrD[Wk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEmzNFEzOyd-MkC5N|AyOjN:L3G+
Patu-S NVHJ[nRDS3m2b4TvfIlkcXS7IHHzd4F6 M4C1O2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHBifHVvUzDj[YxteyCkeTDjdpl{fGGuII\pc4xmfCC|dHHpcolv\yxiSVO1NEA:KDJwOUOg{txONg>? M3rudFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUOwNVI{Lz5{MEmzNFEzOzxxYU6=
Aspc-1 NV\IfJh{S3m2b4TvfIlkcXS7IHHzd4F6 NWn2OWEzS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSXOyYz2xJINmdGy|IHL5JINzgXO2YXygeolwdGW2IIP0ZYlvcW6pLDDJR|UxKD1iMj65O{DPxE1w M3\Q[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUOwNVI{Lz5{MEmzNFEzOzxxYU6=
PANC1 MWrDfZRwfG:6aXPpeJkh[XO|YYm= MXzDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDQRW5EOSClZXzsd{BjgSClconzeIFtKH[rb3zleEB{fGGrbnnu[{whUUN3MDC9JFMvQTRizszNMi=> M2Twe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUOwNVI{Lz5{MEmzNFEzOzxxYU6=
Patu-02 NU\0ZlhOS3m2b4TvfIlkcXS7IHHzd4F6 NVfhU3djS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWGG2dT2wNkBk\WyuczDifUBkenm|dHHsJJZqd2yndDDzeIFqdmmwZzygTWM2OCB;IEOuPVUh|ryPLh?= MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODl|MEGyN{c,OjB7M{CxNlM9N2F-
DAN-G MnK1R5l1d3SxeHnjbZR6KGG|c3H5 MkHPR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSGFPNUdiY3XscJMh[nliY4L5d5RidCC4aX;s[ZQhe3SjaX7pcoctKEmFNUCgQUA1NjN6IN88UU4> MkPTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB7M{CxNlMoRjJyOUOwNVI{RC:jPh?=
Patu-T M3PSWWN6fG:2b4jpZ4l1gSCjc4PhfS=> MULDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjC1MWZWNXKnc3nzeIFvfCCSYYT1MXQh[2WubIOgZpkh[3K7c4ThcEB3cW:uZYSgd5RicW6rbnesJGlEPTBiPTCzN{4zKM7:TT6= NXXvSHR[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC5N|AyOjNpPkKwPVMxOTJ|PD;hQi=>
Hep2 MmL4RY51cWOjbnPldkBie3OjeR?= NXnJS2lPPDhiaILz M{PtOmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZAzKGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCwMlMh|ryPLh?= NGPXTo09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC3OFQ1PCd-MkGwO|Q1PDR:L3G+
A549 MXTBcpRq[2GwY3XyJIF{e2G7 MnzDOFghcHK| NEnvU5hCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gNk41KM7:TT6= Mkf1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFyN{S0OFQoRjJzMEe0OFQ1RC:jPh?=
HCT15 M3qxRmFvfGmlYX7j[ZIh[XO|YYm= M321R|Q5KGi{cx?= M3HTbWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3QyPSClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gN{43KM7:TT6= MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB5NES0OEc,OjFyN{S0OFQ9N2F-
502713 MoDkRY51cWOjbnPldkBie3OjeR?= MlTQOFghcHK| MY\BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iNUCyO|E{KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTC0MlYh|ryPLh?= NGewSHg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC3OFQ1PCd-MkGwO|Q1PDR:L3G+
DU145 MnzJRY51cWOjbnPldkBie3OjeR?= NHrnbWo1QCCqcoO= MYTBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iRGWxOFUh[2WubIOgZZN{\XO|ZXSgZZMh[2WubDD2bYFjcWyrdImgZYZ1\XJiNEigbJJ{KGK7IGPSRkBie3OjeTygTWM2OCB;IESuPEDPxE1w MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB5NES0OEc,OjFyN{S0OFQ9N2F-
PC3 M4W3fmFvfGmlYX7j[ZIh[XO|YYm= MoDVOFghcHK| NWn0c2x2SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHBEOyClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gNVIh|ryPLh?= M4SzOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEe0OFQ1Lz5{MUC3OFQ1PDxxYU6=
IMR32 NVrrWWxISW62aXPhcoNmeiCjc4PhfS=> NHXmW4w1QCCqcoO= M2rrPGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDJUXI{OiClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gNVgh|ryPLh?= MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB5NES0OEc,OjFyN{S0OFQ9N2F-
MCF7 MmLVR5l1d3SxeHnjbZR6KGG|c3H5 M4[1elMh\GG7cx?= MoK2R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{BmgHC{ZYPzbY5oKHerbHSgeJlx\SCyNUOgZY5lKHKjczDteZRidnRiYX\0[ZIhOyCmYYnzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDRwM{Kg{txONg>? M1jHPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUK2PFA1Lz5{MUGyOlgxPDxxYU6=
KB NUjzUFB2S3m2b4TvfIlkcXS7IHHzd4F6 M{ThUVQ5KGi{cx?= MVLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLRkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMj6xOkDPxE1w Ml\1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFzM{GxNFQoRjJzMUOxNVA1RC:jPh?=
HepG2 NUnXdmxpS3m2b4TvfIlkcXS7IHHzd4F6 M37TbFQ5KGi{cx?= NXjUToZXS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJwN{ig{txONg>? M3:0PFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUOxNVA1Lz5{MUGzNVExPDxxYU6=
K562 Ml;5R5l1d3SxeHnjbZR6KGG|c3H5 NUT1cWh3PDhiaILz MYfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzPEDPxE1w MnXNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFzM{GxNFQoRjJzMUOxNVA1RC:jPh?=
KB NW\kN441S3m2b4TvfIlkcXS7IHHzd4F6 MVWzJIRigXN? NEjaPHBEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMSiClZXzsd{Bi\nSncjCzJIRigXNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVEvQSEQvF2u NHv2UnU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUG0OFYzOSd-MkGxOFQ3OjF:L3G+
MGC803 MVfDfZRwfG:6aXPpeJkh[XO|YYm= MYWzJIRigXN? M4nZS2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ISzhyMzDj[YxteyCjZoTldkA{KGSjeYOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTJwNjFOwG0v M2Pme|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUS0OlIyLz5{MUG0OFYzOTxxYU6=
CNE2 NEDaVWZEgXSxdH;4bYNqfHliYYPzZZk> MYmzJIRigXN? NHvzcXdEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBEVkV{IHPlcIx{KGGodHXyJFMh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOy5zIN88UU4> NXfWW4w1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxOFQ3OjFpPkKxNVQ1PjJzPD;hQi=>
MCF7 Moi5R5l1d3SxeHnjbZR6KGG|c3H5 NVnu[HA4OyCmYYnz NHf3U2pEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFMh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPS5{IN88UU4> NGLUemc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUG0OFYzOSd-MkGxOFQ3OjF:L3G+
L1210 MVLDfZRwfG:6aXPpeJkh[XO|YYm= NFvvO2wzKGSjeYO= NEGzd3hEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBNOTJzMDDj[YxteyCjZoTldkAzKGSjeYOgZpkh[2:3bITldkBkd3WwdHXyJIFv[Wy7c3nzMEBKSzVyIE2gNE42PiEQvF2u NIXJd2w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUKzNlgzQCd-MkGyN|I5Ojh:L3G+
HeLa M3jFZWN6fG:2b4jpZ4l1gSCjc4PhfS=> M3PheFQh\GG7cx?= MmS4R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC0JIRigXNiYomgZ492dHSncjDjc5VvfGW{IHHuZYx6e2m|LDDJR|UxKD1iMD61O{DPxE1w NULmVY94RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGyN|I5OjhpPkKxNlMzQDJ6PD;hQi=>
CEM NGLNeWhEgXSxdH;4bYNqfHliYYPzZZk> NVj6fIFXOyCmYYnz Mnn3R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR2VOKGOnbHzzJIFnfGW{IEOg[IF6eyCkeTDjc5VtfGW{IHPveY51\XJiYX7hcJl{cXNuIFnDOVAhRSBzNDFOwG0v NXW2R4tGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGyN|I5OjhpPkKxNlMzQDJ6PD;hQi=>
HL60 M4DNOmN6fG:2b4jpZ4l1gSCjc4PhfS=> MYe0PEBpenN? M{\Y[WN6fG:2b4jpZ4l1gSCrbjDoeY1idiCKTE[wJINmdGy|IHHzd4V{e2WmIHHzJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB7LkWg{txONg>? M4fuRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMkWwO|AxLz5{MUK1NFcxODxxYU6=
A549 MUDDfZRwfG:6aXPpeJkh[XO|YYm= M2C5fVQ5KGi{cx?= NHG4[plEgXSxdH;4bYNqfHliaX6gbJVu[W5iQUW0PUBk\WyuczDhd5Nme3OnZDDhd{Bk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUGuN{DPxE1w MlfkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF{NUC3NFAoRjJzMkWwO|AxRC:jPh?=
KB M2HaTGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWHH[YRHPzJiaILz NYPu[FFVS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hU0JiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE2NjlizszNMi=> NX\YZpptRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGyO|MxPzJpPkKxNlc{ODd{PD;hQi=>
MDA-MB-231 NVzmfZJSS3m2b4TvfIlkcXS7IHHzd4F6 M1fPXlczKGi{cx?= NIfVdFlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOTEFvTVKtNlMyKGOnbHzzJIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9vKGGodHXyJFczKGi{czygTWM2OCB;IESuO{DPxE1w NInNOZo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5OVM5OSd-MkGyPVU{QDF:L3G+
MCF7 MYLDfZRwfG:6aXPpeJkh[XO|YYm= NI\6TVA4OiCqcoO= MkPiR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkA4OiCqcoOsJGlEPTBiPTC5MlYh|ryPLh?= M4LNdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMkm1N|gyLz5{MUK5OVM5OTxxYU6=
L1210 NXuxWJo5TnWwY4Tpc44h[XO|YYm= MX:yOEBpenN? MYrJcohq[mm2aX;uJI9nKHSqeX3p[Jlt[XSnIIP5cpRp[XOnIHnuJI1wfXOnIFyxNlExKGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[geJJqfGm3bTDy[Yxm[XOnIH\yc40hYzVvM1jd[IVwgHm3cnnkbY5mKGGodHXyJJBz\WmwY4XiZZRqd25iZn;yJFI1KGi{czDifUBtcXG3aXSgd4NqdnSrbHzheIlwdiClb4XueIlv\yxiSVO1NEA:KDBwMEKg{txONg>? MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN|MECxOEc,OjF|M{CwNVQ9N2F-
L1210 M17EWmZ2dmO2aX;uJIF{e2G7 MnHGNlQhcHK| MoHRTY5pcWKrdHnvckBw\iC2aIntbYR6dGG2ZTDzfY51cGG|ZTDpckBud3W|ZTDMNVIyOCClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJJRzcXSrdX2gdoVt\WG|ZTDmdo9uKFt3LUPIYYRmd3i7Y4n0bYRqdmViYX\0[ZIheHKnaX7jeYJifGmxbjDmc5IhOjRiaILzJIJ6KGyrcYXp[EB{[2mwdHnscIF1cW:wIHPveY51cW6pLDDJR|UxKD1iMD6wOkDPxE1w Mo\yQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|M{CwNVQoRjJzM{OwNFE1RC:jPh?=
FM3A NV;oVopQS3m2b4P0ZZRq[yCjY4Tpeol1gSCjc4PhfS=> M{Po[FIh\GG7cx?= MnzSR5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JI1wfXOnIF\NN2Eh[2WubIOgZYZ1\XJiMjDkZZl{KGK7IHPveYx1\XJiY3;1cpRqdmdiYX7hcJl{cXNuIFnDOVAhRSByLkG4JO69VS5? MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN|MECxOEc,OjF|M{CwNVQ9N2F-
HeLa MWPDfZRwe3SjdHnjJIFkfGm4aYT5JIF{e2G7 M3LVZ2N6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIlvKHC{ZYPlcoNmKG:oIEKwJJVOKDJpLXTlc5h6fXKrZHnu[UwhUUN3MDC9JFAvOThizszNMi=> M1j6cFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{OwNFE1Lz5{MUOzNFAyPDxxYU6=
L1210 M3WyUWZ2dmO2aX;uJIF{e2G7 MXi0JIhzew>? MX7Jcohq[mm2aX;uJI9nKHSqeX3p[Jlt[XSnIIP5cpRp[XOnIHnuJI1wfXOnIFyxNlExKGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[geJJqfGm3bTDy[Yxm[XOnIH\yc40hYzVvM1jd[IVwgHm3cnnkbY5mKGGodHXyJJBz\WmwY4XiZZRqd25iZn;yJFQhcHK|IHL5JIxqeXWrZDDzZ4lvfGmubHH0bY9vKGOxdX70bY5oNCCLQ{WwJF0hOC5{MjFOwG0v MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN|MECxOEc,OjF|M{CwNVQ9N2F-
L1210 M321R2Z2dmO2aX;uJIF{e2G7 M{PzZ|I1KGi{cx?= MX;Jcohq[mm2aX;uJI9nKESQQTDzfY51cGW|aYOgbY4hdW:3c3WgUFEzOTBiY3XscJMh[XO|ZYPz[YQh[XNiW{[tN2heOidvZHXvfJl2emmmaX7lJIlv[2:{cH;yZZRqd25iaX6geI8hTE6DIIDy[Ylv[3WkYYTl[EBnd3JiMkSgbJJ{KGK7IHzpdZVq\CC|Y3nueIltdGG2aX;uJINwfW62aX7nMEBKSzVyIE2gNE4{PyEQvF2u MnjyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|M{CwNVQoRjJzM{OwNFE1RC:jPh?=
HeLa MVPDfZRwe3SjdHnjJIFkfGm4aYT5JIF{e2G7 Ml25N{Bl[Xm| NGPpU5lEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjCzJIRigXNiYomgZ492dHSncjDjc5VvfGmwZzDhcoFtgXOrczygTWM2OCB;IECuOFUh|ryPLh?= MofxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|M{CwNVQoRjJzM{OwNFE1RC:jPh?=
L1210 NVvUNlVmS3m2b4P0ZZRq[yCjY4Tpeol1gSCjc4PhfS=> M3LvTmN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDMNVIyOCClZXzsd{BqdiCycnXz[Y5k\SCxZjC1NFAhfU1idYLhZ4ltNCCLQ{WwJF0hOC52NzFOwG0v NGToXWk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUOzNFAyPCd-MkGzN|AxOTR:L3G+
L1210 MV\DfZRwe3SjdHnjJIFkfGm4aYT5JIF{e2G7 NGHFVW4zKGSjeYO= M2jzR2N6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDMNVIyOCClZXzsd{Bi\nSncjCyJIRigXNiYomgZ492dHSncjDjc5VvfGmwZzDhcoFtgXOrczygTWM2OCB;IECuOVYh|ryPLh?= M2LFRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{OwNFE1Lz5{MUOzNFAyPDxxYU6=
L1210 MlrqSpVv[3Srb36gZZN{[Xl? NGXreG41KGi{cx?= MofoTY5pcWKrdHnvckBw\iC2aIntbYR6dGG2ZTDzfY51cGG|ZTDpckBud3W|ZTDMNVIyOCClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJJRzcXSrdX2gdoVt\WG|ZTDmdo9uKFt3LUPIYYRmd3i7Y4n0bYRqdmViYX\0[ZIheHKnaX7jeYJifGmxbjDmc5IhPCCqcoOgZpkhdGmzdXnkJJNkcW62aXzsZZRqd25iY3;1cpRqdmduIFnDOVAhRSByLk[g{txONg>? NVjaUINCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzN|AxOTRpPkKxN|MxODF2PD;hQi=>
L1210 NWf2fppGS3m2b4P0ZZRq[yCjY4Tpeol1gSCjc4PhfS=> NYrhbYh{S3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KG2xdYPlJGwyOjFyIHPlcIx{KGmwIIDy[ZNmdmOnIH;mJFUxOCC3TTD1dollcW6nLDDJR|UxKD1iMD62NkDPxE1w M1jVdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{OwNFE1Lz5{MUOzNFAyPDxxYU6=
L1210 MXjGeY5kfGmxbjDhd5NigQ>? MkXaTY5pcWKrdHnvckBw\iCGTlGgd5lvfGinc3nzJIlvKG2xdYPlJGwyOjFyIHPlcIx{KGG|c3Xzd4VlKGG|IGu2MVNJZTJpLXTlc5h6fXKrZHnu[UBqdmOxcoDvdoF1cW:wIHnuJJRwKESQQTDifUBtcXG3aXSgd4NqdnSrbHzheIlwdiClb4XueIlv\yxiSVO1NEA:KDBwOUeg{txONg>? MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN|MECxOEc,OjF|M{CwNVQ9N2F-
HeLa MUfDfZRwe3SjdHnjJIFkfGm4aYT5JIF{e2G7 MVfDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDpckBxemW|ZX7j[UBw\iB3MECgeW0hfXKjY3nsMEBKSzVyIE2gNUDPxE1w MkHBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|M{CwNVQoRjJzM{OwNFE1RC:jPh?=
HeLa NH\M[5dEgXSxc4TheIlkKGGldHn2bZR6KGG|c3H5 M{XMdmN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIlvKHC{ZYPlcoNmKG:oIEWwNEB2VSC3cnnkbY5mNCCLQ{WwJF0hOS5zIN88UU4> M3fYcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{OwNFE1Lz5{MUOzNFAyPDxxYU6=
L1210 MXnDfZRwe3SjdHnjJIFkfGm4aYT5JIF{e2G7 MoLJR5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JI1wfXOnIFyxNlExKGOnbHzzJIlvKHC{ZYPlcoNmKG:oIEKwJJVOKDJpLXTlc5h6fXKrZHnu[UwhUUN3MDC9JFEvOyEQvF2u NWfCSnFIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzN|AxOTRpPkKxN|MxODF2PD;hQi=>
HeLa NFLTSWxEgXSxc4TheIlkKGGldHn2bZR6KGG|c3H5 NGPHfZFEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{BqdiCycnXz[Y5k\SCxZjCyNEB2VSC2aIntbYRqdmVuIFnDOVAhRSBzLkWg{txONg>? MkDhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|M{CwNVQoRjJzM{OwNFE1RC:jPh?=
L1210 M4fL[2Z2dmO2aX;uJIF{e2G7 MWmyOEBpenN? NX3uTlZKUW6qaXLpeIlwdiCxZjDSUmEhe3mwdHjld4l{KGmwIH3veZNmKExzMkGwJINmdGy|IHHzd4V{e2WmIHHzJHs2NTOKXYXybYRqdmViaX7jc5Jxd3KjdHnvckBqdiC2bzDSUmEheHKnaX7jeYJifGWmIH\vdkAzPCCqcoOgZpkhdGmzdXnkJJNkcW62aXzsZZRqd25iY3;1cpRqdmduIFnDOVAhRSB2Lkmg{txONg>? MnfxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|M{CwNVQoRjJzM{OwNFE1RC:jPh?=
L1210 NED5S|JHfW6ldHnvckBie3OjeR?= MnnmNVUhdWmwcx?= NIHEOWdKdmirYnn0bY9vKG:oIITofY1q\HmuYYTlJJN6dnSqYYPlJIlvKG2xdYPlJGwyOjFyIHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4YhfHKrdHn1cUBz\WynYYPlJIZzd21iW{WtN2he\GWxeIn1dollcW6nIHHmeIVzKHC{ZXnuZ5Vj[XSrb36g[o9zKDF3IH3pcpMh[nlibHnxeYllKHOlaX70bYxt[XSrb36gZ492dnSrbnesJGlEPTBiPTC3JO69VS5? NFfyS|A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUOzNFAyPCd-MkGzN|AxOTR:L3G+
CEM NHTWU2VEgXSxc4TheIlkKGGldHn2bZR6KGG|c3H5 M{fBN|Mh\GG7cx?= NU\0PY1[S3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGNGVSClZXzsd{Bi\nSncjCzJIRigXNiYomgZ492dHSncjDjc5VvfGmwZzDhcoFtgXOrczygTWM2OCB;IEG0JO69VS5? MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN|MECxOEc,OjF|M{CwNVQ9N2F-
L1210 M1LPVGN6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= NIK1dlVEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhdW:3c3WgUFEzOTBiY3XscJMhcW5icILld4Vv[2Vib3[gNlAhfU1idHj5cYllcW6nLDDJR|UxKD1iMkGg{txONg>? MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN|MECxOEc,OjF|M{CwNVQ9N2F-
HL60 NE\YZWpEgXSxdH;4bYNqfHliYYPzZZk> Mn7oOFghcHK| NVnibFZ5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEx4MDDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hQS5zIN88UU4> MnroQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|OEG2PVYoRjJzM{ixOlk3RC:jPh?=
CEM NYH2RYF7S3m2b4TvfIlkcXS7IHHzd4F6 M2PSWFczKGi{cx?= NHvIU3hEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBETU1iY3XscJMh[W[2ZYKgO|IhcHK|IHL5JJRzgXCjbjDicJVmKGG|c3H5MEBKSzVyIE2gPEDPxE1w NGOzXGU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUSzPVY6OCd-MkG0N|k3QTB:L3G+
CEM MVvDfZRwfG:6aXPpeJkh[XO|YYm= NHPsSXY1QCCqcoO= NFPIcW5EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBETU1iY3XscJMh[W[2ZYKgOFghcHK|IHL5JJRzgXCjbjDicJVmKGG|c3H5MEBKSzVyIE2gNVUh|ryPLh?= NV\FSo1URGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG0N|k3QTBpPkKxOFM6PjlyPD;hQi=>
CEM MmTiR5l1d3SxeHnjbZR6KGG|c3H5 NXiyb4pEPzJiaILz M3\pUmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNGVSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|Ah|ryPLh?= MmHxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2M{m2PVAoRjJzNEO5OlkxRC:jPh?=
CEM NWfMXXpFS3m2b4TvfIlkcXS7IHHzd4F6 MYW0PEBpenN? MXvDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IESwJO69VS5? M3r2UlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNEO5OlkxLz5{MUSzPVY6ODxxYU6=
K562 NE[5cnpCdnSrY3HuZ4VzKGG|c3H5 NEK5UppCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gT|U3OiClZXzsd{whUUN3MDC9JFIvPCEQvF2u NE\n[mE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUS0PVYyOCd-MkG0OFk3OTB:L3G+
COLO205 MkXyRY51cWOjbnPldkBie3OjeR?= M4TQV2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDU2xQOjB3IHPlcIx{NCCLQ{WwJF0hPC5zNzFOwG0v M2LRPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNES5OlExLz5{MUS0PVYyODxxYU6=
KM12 MoG1RY51cWOjbnPldkBie3OjeR?= NEDYbIZCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gT20yOiClZXzsd{whUUN3MDC9JFgvOzJizszNMi=> NI\OeFg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUS0PVYyOCd-MkG0OFk3OTB:L3G+
HCT116 M37pPGFvfGmlYX7j[ZIh[XO|YYm= NFjVNWpCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{NCCLQ{WwJF0hQC53MTFOwG0v M2rh[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNES5OlExLz5{MUS0PVYyODxxYU6=
HCT15 MUTBcpRq[2GwY3XyJIF{e2G7 NHLZSnBCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGNVOTViY3XscJMtKEmFNUCgQUA6NjdzIN88UU4> MlTEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2NEm2NVAoRjJzNES5OlExRC:jPh?=
HT-29 NE\ifItCdnSrY3HuZ4VzKGG|c3H5 NE\WeGNCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTHQuOjliY3XscJMtKEmFNUCgQUAyOC5{IN88UU4> NGPQd2Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUS0PVYyOCd-MkG0OFk3OTB:L3G+
HCC2998 NXf2c2F2SW62aXPhcoNmeiCjc4PhfS=> MXjBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPDNlk6QCClZXzsd{whUUN3MDC9JFE{NjVizszNMi=> MlfMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2NEm2NVAoRjJzNES5OlExRC:jPh?=
CCRF-CEM M3fxUWFvfGmlYX7j[ZIh[XO|YYm= MX7BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1PSSk1ETU1iY3XscJMtKEmFNUCgQUA{Oy5zIN88UU4> NXW0clRDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG0OFk3OTBpPkKxOFQ6PjFyPD;hQi=>
MIAPaCa2 NUXvT|lMSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NWT2OnZXPzJiaILz NVHSOJBzSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNTWFR[UOjMjDj[YxteyCjZoTldkA4OiCqcoOsJGlEPTBiPTC3MlQh|ryPLh?= MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR3OEGxN{c,OjF2NUixNVM9N2F-
COLO320 MVTBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NFX0SZI4OiCqcoO= NVPpNGd3SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDU2xQOzJyIHPlcIx{KGGodHXyJFczKGi{czygTWM2OCB;IEiuO{DPxE1w MoDEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2NUixNVMoRjJzNEW4NVE{RC:jPh?=
COLO320 MUPBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NE[xeXI1QCCqcoO= NFT4OI9CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFPPUG8{OjBiY3XscJMh[W[2ZYKgOFghcHK|LDDJR|UxKD1iMUCg{txONg>? NGrxVIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUS1PFEyOyd-MkG0OVgyOTN:L3G+
MIAPaCa2 NEW0dFRCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MmfYOFghcHK| MmPHRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPSVHQZWNiOiClZXzsd{Bi\nSncjC0PEBpenNuIFnDOVAhRSBzNDFOwG0v NF;NO5o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUS1PFEyOyd-MkG0OVgyOTN:L3G+
MCF7 MljlRY51cXS3bX;yJIF{e2G7 MUK3NkBpenN? MWPBcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB5LkW0JO69VS5? MnqzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2OE[2PVQoRjJzNEi2Olk1RC:jPh?=
EC9706 NYrpeVBJSW62aYT1cY9zKGG|c3H5 MlnTO|IhcHK| NIPRd2xCdnSrdIXtc5Ih[WO2aY\peJkh[WejaX7zeEBpfW2jbjDFR|k4ODZiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIxNjNizszNMi=> MoroQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2OE[2PVQoRjJzNEi2Olk1RC:jPh?=
SPC-A1 M3L2SWFvfGm2dX3vdkBie3OjeR?= NYnkSY5sPzJiaILz M1zmfmFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPQR{1COSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlYvQTJizszNMi=> NXr3b3VKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG0PFY3QTRpPkKxOFg3Pjl2PD;hQi=>
PC3 MWPBcpRqfHWvb4KgZZN{[Xl? NHPCc|g4OiCqcoO= M{HBWmFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGDDN{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMkmuN{DPxE1w MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR6Nk[5OEc,OjF2OE[2PVQ9N2F-
HeLa M3ntOGFvfGm2dX3vdkBie3OjeR?= M2rmZlczKGi{cx?= M4HMXWFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IESxMlQ3KM7:TT6= MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR6Nk[5OEc,OjF2OE[2PVQ9N2F-
ZR-75-1 MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWC0PEBpenN? M{LLcWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJHpTNTd3LUGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCyMlMh|ryPLh?= NIjlWpY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUS4PVgxOid-MkG0PFk5ODJ:L3G+
A549 NYTVVVNoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlvkOFghcHK| NIC0XG5Iem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMj60JO69VS5? M2\jXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNEi5PFAzLz5{MUS4PVgxOjxxYU6=
COLO205 Mn7mS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYD0XnI6PDhiaILz NFvSfYlIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBEV0yRMkC1JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNk45KM7:TT6= M1n5TFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNEi5PFAzLz5{MUS4PVgxOjxxYU6=
MCF7 NX7pbGpNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHfjSYg1QCCqcoO= M4rVemdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB{Lkig{txONg>? MkDDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2OEm4NFIoRjJzNEi5PFAzRC:jPh?=
Gurav MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIDzRpU1QCCqcoO= MXTHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDHeZJifiClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDNwMTFOwG0v NHi4XIc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUS4PVgxOid-MkG0PFk5ODJ:L3G+
A2780 NWLpeG15T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{SyTFQ5KGi{cx?= MkSyS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gRVI4QDBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB|LkWg{txONg>? NYDkbXE5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG0PFk5ODJpPkKxOFg6QDB{PD;hQi=>
HOP62 M2XN[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1fzelQ5KGi{cx?= M3i1[2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGhQWDZ{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iND6xJO69VS5? NX;tU4ZbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG0PFk5ODJpPkKxOFg6QDB{PD;hQi=>
KB MnPJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3;rSVQ5KGi{cx?= MVzHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDLRkBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFUvOiEQvF2u MknmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2OEm4NFIoRjJzNEi5PFAzRC:jPh?=
DWD NIn6VVBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mn\TOFghcHK| MoDnS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gSHdFKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hPi5zIN88UU4> MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR6OUiwNkc,OjF2OEm4NFI9N2F-
SiHa NXXtTHlwT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV3YfXNyPDhiaILz MV3Hdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDTbWhiKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hPi5|IN88UU4> NFfXNHo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUS4PVgxOid-MkG0PFk5ODJ:L3G+
PC3 NF;HeHpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFnVOlE1QCCqcoO= NITBWXZIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBRSzNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSBzMjFOwG0v MkGyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2OEm4NFIoRjJzNEi5PFAzRC:jPh?=
SMMC7721 M{fLUmN6fG:2b4jpZ4l1gSCjc4PhfS=> NX34SGZrS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW02PQ{e3NlEh[2WubIOsJGlEPTBiPTCxN{DPxE1w MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR7NU[1PUc,OjF2OUW2OVk9N2F-
A549 NYHUbIFZS3m2b4TvfIlkcXS7IHHzd4F6 MlvjR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{whUUN3MDC9JFE{NjdizszNMi=> MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR7NU[1PUc,OjF2OUW2OVk9N2F-
Bel7402 NFHtcVdEgXSxdH;4bYNqfHliYYPzZZk> NFi5WIZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBD\Wx5NECyJINmdGy|LDDJR|UxKD1iMkGuPEDPxE1w MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR7NU[1PUc,OjF2OUW2OVk9N2F-
A549 M{j6b2N6fG:2b4jpZ4l1gSCjc4PhfS=> M3LRZ2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNT62JO69VS5? MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTVzNUC0OEc,OjF3MUWwOFQ9N2F-
QGY M1LVU2N6fG:2b4jpZ4l1gSCjc4PhfS=> MVjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDRS3kh[2WubIOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTRwMTFOwG0v MmjRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3MUWwOFQoRjJzNUG1NFQ1RC:jPh?=
HeLa MXjDfZRwfG:6aXPpeJkh[XO|YYm= NYnsWoFTS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOk4yKM7:TT6= MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTVzNUC0OEc,OjF3MUWwOFQ9N2F-
SW620 MWjBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MYm3NkBpenN? MkHoRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVV{[yNEBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz6zPEDPxE1w M1;CU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNUK0PFI6Lz5{MUWyOFgzQTxxYU6=
HeLa MVTBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MkTCO|IhcHK| NWDrbW51SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNE4{OSEQvF2u NF\0WXk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWyOFgzQSd-MkG1NlQ5Ojl:L3G+
MIAPaCa2 Mm\YRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MlLsO|IhcHK| M{P6fGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVnBVIFE[TJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEyNjR3IN88UU4> M3rISVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNUK0PFI6Lz5{MUWyOFgzQTxxYU6=
WI38 NVfwdWVHSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M33Qd|czKGi{cx?= NET1e3hCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGfJN|gh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG4MlUh|ryPLh?= M1P0O|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNUK0PFI6Lz5{MUWyOFgzQTxxYU6=
SKBR3 MXrBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NFTWT2o4OiCqcoO= NFzaSlJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPLRnI{KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzPE4zPSEQvF2u MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTV{NEiyPUc,OjF3MkS4Nlk9N2F-
MCF7 Moe3RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M{\Qe|czKGi{cx?= NVLXUYZpSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0Nk4xOSEQvF2u MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTV{NEiyPUc,OjF3MkS4Nlk9N2F-
PA1 NEnhTXRCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M2LvOVQ5KGi{cx?= NWT2O4pRSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQRVEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IILld4F7fXKrbjDy[YR2[3Srb36geIV{fCxiSVO1NEA:KDVizszNMi=> MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTV|MECxOkc,OjF3M{CwNVY9N2F-
MCF7 NVi2UHhzSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NY\JeXZZPDhiaILz Moe1RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC{ZYPhfpVzcW5icnXkeYN1cW:wIITld5QtKEmFNUCgQUAyPSEQvF2u NFrlUXI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWzNFAyPid-MkG1N|AxOTZ:L3G+
HeLa M3K5UGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWnnOm1TOyCmYYnz NX35NpFVS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjZoTldkA{KGSjeYOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPCEQvF2u MlXmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF4MUK5N|UoRjJzNkGyPVM2RC:jPh?=
MG63 NUmyeFExS3m2b4TvfIlkcXS7IHHzd4F6 MYqzJIRigXN? NWfSb4FuS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUd4MzDj[YxteyCjZoTldkA{KGSjeYOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hQCEQvF2u MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTZzMkmzOUc,OjF4MUK5N|U9N2F-
L1210 Ml\iR5l1d3SxeHnjbZR6KGG|c3H5 Mm\DO|IhcHK| MXzDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W|ZTDMNVIyOCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE4xODByMEGxJO69VS5? M2fpPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNkSwOVk1Lz5{MU[0NFU6PDxxYU6=
P388 MXfDfZRwfG:6aXPpeJkh[XO|YYm= MknyO|IhcHK| NFPVcYtEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBROzh6IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjByMECwNVch|ryPLh?= M2HCOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNkSwOVk1Lz5{MU[0NFU6PDxxYU6=
HL60 MnHCR5l1d3SxeHnjbZR6KGG|c3H5 MYe3NkBpenN? M1zXcGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhNPjBiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODByMECyO{DPxE1w M{TiflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNkSwOVk1Lz5{MU[0NFU6PDxxYU6=
KB M2PUfGN6fG:2b4jpZ4l1gSCjc4PhfS=> NXK4b5g5PzJiaILz MX3DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLRkBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD6wNFAxODd5IN88UU4> MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTZ2MEW5OEc,OjF4NEC1PVQ9N2F-
IEC-6 MYPDfZRwfG:6aXPpeJkh[XO|YYm= NHjhO5I3KGSjeYO= MnXiR5l1d3SxeHnjbZR6KGGpYXnud5QhemG2IFnFR{03KGOnbHzzJIFnfGW{IE[g[IF6eyCkeTDTVmIh[2:ub4LpcYV1emmlIHHzd4F6NCCLQ{WwJF0hOC54NjFOwG0v MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTZ6NEC0O{c,OjF4OESwOFc9N2F-
MCF10A NUHmNJd7S3m2b4TvfIlkcXS7IHHzd4F6 NGDOTZQ3KGSjeYO= NEmzTpVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0ZzMFGgZ4VtdHNiYX\0[ZIhPiCmYYnzJIJ6KFOUQjDjc4xwemmvZYTybYMh[XO|YYmsJGlEPTBiPTCwMlc{KM7:TT6= NXrBNpdzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG2PFQxPDdpPkKxOlg1ODR5PD;hQi=>
HT-29 M2HneWN6fG:2b4jpZ4l1gSCjc4PhfS=> M3:1PFYh\GG7cx?= MlG0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQuOjliY3XscJMh[W[2ZYKgOkBl[Xm|IHL5JHNTSiClb3zvdolu\XS{aXOgZZN{[XluIFnDOVAhRSBzLkC4JO69VS5? M4XKSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNki0NFQ4Lz5{MU[4OFA1PzxxYU6=
MCF7 M{jSfWN6fG:2b4jpZ4l1gSCjc4PhfS=> MX62JIRigXN? NHv5SnBEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFYh\GG7czDifUBUWkJiY3;sc5JqdWW2cnnjJIF{e2G7LDDJR|UxKD1iND6zNkDPxE1w NU\BToY5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG2PFQxPDdpPkKxOlg1ODR5PD;hQi=>
DU145 MnfYR5l1d3SxeHnjbZR6KGG|c3H5 MUDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDEWVE1PSClZXzsd{whUUN3MDC9JFMvOyEQvF2u NEX2ZYw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUe3OFQ4PCd-MkG3O|Q1PzR:L3G+
NCI-H460 MmP4R5l1d3SxeHnjbZR6KGG|c3H5 MnzTR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUmNKNUh2NkCgZ4VtdHNuIFnDOVAhRSB6LkWg{txONg>? NYfRbJZwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3O|Q1PzRpPkKxO|c1PDd2PD;hQi=>
MCF7 Mly0R5l1d3SxeHnjbZR6KGG|c3H5 M1TSfWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMtKEmFNUCgQUA{OSEQvF2u NHfLcHA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUe3OFQ4PCd-MkG3O|Q1PzR:L3G+
KB MUPDfZRwfG:6aXPpeJkh[XO|YYm= NIK1Ulg{KGSjeYO= M33nRmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGtDKGOnbHzzJIFnfGW{IEOg[IF6eyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNk42KM7:TT6= NWnGPGdtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4OFM6OzlpPkKxPFQ{QTN7PD;hQi=>
HeLa M1PJeWN6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= NYHXOZlJPzJiaILz M3HWcmN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEB1cHmvaXTpcoUuc2mwYYPlJIRm\mmlaXXueEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDj[YxtKGOxdX70bY5oNCCLQ{WwJF0hOC5{MzFOwG0v MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh7MkiyPUc,OjF6OUK4Nlk9N2F-
L1210 NYf1fGxPS3m2b4P0ZZRq[yCjY4Tpeol1gSCjc4PhfS=> M4PXXVQ5KGi{cx?= NGrnSpREgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhfGi7bXnkbY5mNWurbnHz[UBl\W[rY3nlcpQhdW:3c3WgUFEzOTBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JINmdGxiY3;1cpRqdmduIFnDOVAhRSByLkOyJO69VS5? M{XwZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEmyPFI6Lz5{MUi5NlgzQTxxYU6=
HeLa NEPDN21EgXSxc4TheIlkKGGldHn2bZR6KGG|c3H5 M2j0cFczKGi{cx?= NVjQSZBJS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JINmdGxiY3;1cpRqdmduIFnDOVAhRSByLkW0JO69VS5? NUW5SlJQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4PVI5OjlpPkKxPFkzQDJ7PD;hQi=>
CEM MkS3R5l1d3O2YYTpZ{Bi[3Srdnn0fUBie3OjeR?= NYGzWZdmPzJiaILz M{TMVGN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEB1cHmvaXTpcoUuc2mwYYPlJIRm\mmlaXXueEBpfW2jbjDDSW0h[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IHPlcIwh[2:3boTpcoctKEmFNUCgQUAyOiEQvF2u MoHVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6OUK4NlkoRjJzOEmyPFI6RC:jPh?=
CEM/0 MXzDfZRwe3SjdHnjJIFkfGm4aYT5JIF{e2G7 MVK3NkBpenN? NFXTNHlEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gR2VONzBiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JINmdGxiY3;1cpRqdmduIFnDOVAhRSBzODFOwG0v Mm\KQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6OUK4NlkoRjJzOEmyPFI6RC:jPh?=
L1210 M1jrOmN6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= MUTDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViTEGyNVAh[2WubIOsJGlEPTBiPTCwMlQ6KM7:TT6= NVfkU|ZPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG5NVc{PjNpPkKxPVE4OzZ|PD;hQi=>
HeLa NF3WUJVEgXSxc4TheIlkKGGldHn2bZR6KGG|c3H5 NEfJXlZEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{whUUN3MDC9JFAvPTRizszNMi=> NFfjNGc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUmxO|M3Oyd-MkG5NVc{PjN:L3G+
CEM NEH5bFFEgXSxc4TheIlkKGGldHn2bZR6KGG|c3H5 NGToRotEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gR2VOKGOnbHzzMEBKSzVyIE2gNVgh|ryPLh?= NHrveXI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUmxO|M3Oyd-MkG5NVc{PjN:L3G+
A549 NE\q[4REgXSxdH;4bYNqfHliYYPzZZk> M3fPd|Mh\GG7cx?= NVv1Wmw2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA{KGSjeYOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC52MjFOwG0v NIDPUVE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkCwNFkzPSd-MkKwNFA6OjV:L3G+
HepG2 M4L2PGN6fG:2b4jpZ4l1gSCjc4PhfS=> NGTkbog{KGSjeYO= MVvDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjCzJIRigXNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNk44KM7:TT6= MnXjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJyMEC5NlUoRjJ{MECwPVI2RC:jPh?=
BCG823 MXjDfZRwfG:6aXPpeJkh[XO|YYm= M2OwdlMh\GG7cx?= MmnJR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRmNIQDJ|IHPlcIx{KGGodHXyJFMh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUA3NjF3IN88UU4> NUnUcmptRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwNFA6OjVpPkKyNFAxQTJ3PD;hQi=>
colon cancer cell MlG3R5l1d3SxeHnjbZR6KGG|c3H5 NV3oW2h1PDhiaILz NHLaWXVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBkd2yxbjDjZY5k\XJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JINwfWy2ZYKgZ492dnSrbnesJGdKPTBiPTC4MlQh|ryPLh?= NUDsO5oyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwOVYzPzdpPkKyNFU3Ojd5PD;hQi=>
leukemia cell MYfDfZRwfG:6aXPpeJkh[XO|YYm= Mkf1OFghcHK| M4PDSGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJIxmfWunbXnhJINmdGy|IHHmeIVzKDR6IHjyd{BjgSClb4XseIVzKGOxdX70bY5oNCCJSUWwJF0hOTVwMTFOwG0v MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB3NkK3O{c,OjJyNU[yO|c9N2F-
prostate cancer cell NGT0Tm9EgXSxdH;4bYNqfHliYYPzZZk> M1TVelQ5KGi{cx?= M4jsbGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJJBzd3O2YYTlJINidmOncjDj[YxteyCjZoTldkA1QCCqcoOgZpkh[2:3bITldkBkd3WwdHnu[{whT0l3MDC9JFIzNjdizszNMi=> NILEUHo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkC1OlI4Pyd-MkKwOVYzPzd:L3G+
renal cancer cell MnfpR5l1d3SxeHnjbZR6KGG|c3H5 NXi1[I1vPDhiaILz M2LPV2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJJJmdmGuIHPhcoNmeiClZXzsd{Bi\nSncjC0PEBpenNiYomgZ492dHSncjDjc5VvfGmwZzygS2k2OCB;IES1MlYh|ryPLh?= MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB3NkK3O{c,OjJyNU[yO|c9N2F-
MCF7 NHvMOZFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M3HMNVczKGi{cx?= NH34R3ZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlch[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEmuOlch|ryPLh?= M3PMTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MEe5N|c5Lz5{MkC3PVM4QDxxYU6=
KB M1fJbGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 Mo\mO|IhcHK| MY\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEuEIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA6Njh3IN88UU4> NILUc289[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkC3PVM4QCd-MkKwO|k{Pzh:L3G+
GLC82 MkPmRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MnPiO|IhcHK| M4fpV2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iR1zDPFIh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG1MlUh|ryPLh?= MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB5OUO3PEc,OjJyN{mzO|g9N2F-
MGC803 NHvZUHFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MmrTO|IhcHK| NYrjSVB5SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNS2M5ODNiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE3NjZizszNMi=> MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB5OUO3PEc,OjJyN{mzO|g9N2F-
CNE2 M{P2cGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M37kOFczKGi{cx?= MlmzRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCFTlWyJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzNz6yJO69VS5? MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB5OUO3PEc,OjJyN{mzO|g9N2F-
HEK293 NVHFVpJPS3m2b4TvfIlkcXS7IHHzd4F6 NHfJN3czKGSjeYO= NIHBdHVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJTUt{OUOgZ4VtdHNiYX\0[ZIhOiCmYYnzJIJ6KGGuYX3hdkBjdHWnIHHzd4F6NCCLQ{WwJF0hPDJwOTFOwG0v NHm4PJA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkC5N|c3OSd-MkKwPVM4PjF:L3G+
colon cancer cell MorUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2HiTVQ5KGi{cx?= MWXHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDjc4xwdiClYX7j[ZIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IHPveYx1\XJiY3;1cpRmeiCvZYToc4QtKEeLNUCgQUA5NjRizszNMi=> MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjFzOUG1NUc,OjJzMUmxOVE9N2F-
leukemia cell NWLEd3BzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYTZRotWPDhiaILz MlqxS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gcIV2c2WvaXGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KGOxdXz0[ZIh[2:3boTldkBu\XSqb3SsJGdKPTBiPTCxOU4yKM7:TT6= M1vmPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUG5NVUyLz5{MkGxPVE2OTxxYU6=
prostate cancer cell M1i5Wmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHOxTVE1QCCqcoO= NVTiRoZtT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4heHKxc4TheIUh[2GwY3XyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSClb4XseIVzKGOxdX70[ZIhdWW2aH;kMEBIUTVyIE2gNlIvPyEQvF2u MoC4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzMUmxOVEoRjJ{MUG5NVUyRC:jPh?=
renal cancer cell M3vXe2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmPxOFghcHK| M13rSWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJJJmdmGuIHPhcoNmeiClZXzsd{Bi\nSncjC0PEBpenNiYomgZ492dHSncjDjc5VvfGW{IH3leIhw\CxiR1m1NEA:KDR3Lk[g{txONg>? Mnj0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzMUmxOVEoRjJ{MUG5NVUyRC:jPh?=
H460 NHrySnpEgXSxdH;4bYNqfHliYYPzZZk> MWq3NkBpenN? NUSyRVFPS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUDR4MDDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOyEQvF2u MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF|MEGzNkc,OjJzM{CxN|I9N2F-
HCT116 MXPDfZRwfG:6aXPpeJkh[XO|YYm= M2DUelczKGi{cx?= M2HWPWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDFzNjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPCEQvF2u Mn;pQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzM{CxN|IoRjJ{MUOwNVMzRC:jPh?=
MCF7 M4CxfGN6fG:2b4jpZ4l1gSCjc4PhfS=> MWq3NkBpenN? NEPHRXVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPCEQvF2u NV\5XVVTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxN|AyOzJpPkKyNVMxOTN{PD;hQi=>
A549 M3LicWN6fG:2b4jpZ4l1gSCjc4PhfS=> MX:yOEBpenN? NH3GT49EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA2NjZ2IN88UU4> MnvkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzOEK5NlYoRjJ{MUiyPVI3RC:jPh?=
QGY7701 M3jlbGN6fG:2b4jpZ4l1gSCjc4PhfS=> MV:yOEBpenN? Mlv6R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVWd[PzdyMTDj[YxteyCjZoTldkAzPCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTRwMzFOwG0v MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF6MkmyOkc,OjJzOEK5NlY9N2F-
SW480 MlvFR5l1d3SxeHnjbZR6KGG|c3H5 MnHDNlQhcHK| MWTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTW|Q5OCClZXzsd{Bi\nSncjCyOEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUvPzFizszNMi=> MmT0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzOEK5NlYoRjJ{MUiyPVI3RC:jPh?=
HeLa MnTRR5l1d3SxeHnjbZR6KGG|c3H5 Mof0NlQhcHK| NFrCPIdEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPi5|MjFOwG0v NYe2RnVNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxPFI6OjZpPkKyNVgzQTJ4PD;hQi=>
KB NHfyUWxEgXSxdH;4bYNqfHliYYPzZZk> M1X6V|czKGi{cx?= MmfPR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT2Ih[2WubIOgZYZ1\XJiN{KgbJJ{KG67IF3UWEBie3OjeTygTWM2OCB;IEmg{txONg>? NITQV4w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkKwNFQxPCd-MkKyNFA1ODR:L3G+
CNE2 MmXkR5l1d3SxeHnjbZR6KGG|c3H5 NX;zfpNqPzJiaILz M1y4b2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNPTTJiY3XscJMh[W[2ZYKgO|IhcHK|IH75JG1VXCCjc4PhfUwhUUN3MDC9JFE{NjVizszNMi=> NEjUR2U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkKwNFQxPCd-MkKyNFA1ODR:L3G+
HepG2 NGWwOY9CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MW[0PEBpenN? NWDUS4ZvSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUvQTJizszNMi=> NEXid3M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkKwPVQ5Pid-MkKyNFk1QDZ:L3G+
NCI-H460 MWDDfZRwfG:6aXPpeJkh[XO|YYm= NH\kZmxEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBPS0lvSES2NEBk\WyuczygTWM2OCB;IEig{txONg>? M3LkPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MkizOFUyLz5{MkK4N|Q2OTxxYU6=
SMMC7721 NFH5VHpEgXSxdH;4bYNqfHliYYPzZZk> M3nzWWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNOVUN5N{KxJINmdGy|LDDJR|UxKD1iMUWg{txONg>? NHfMb2E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkK4N|Q2OSd-MkKyPFM1PTF:L3G+
MCF7 M2[zbGN6fG:2b4jpZ4l1gSCjc4PhfS=> Ml3PR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{whUUN3MDC9JFMyKM7:TT6= MlXqQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ{OEO0OVEoRjJ{MkizOFUyRC:jPh?=
NCI-H460 NX\QcHlVS3m2b4TvfIlkcXS7IHHzd4F6 NGjuU201QCCqcoO= M1zUXGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KNE[wJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{OTFOwG0v NIDJfYc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkOwOFM1PCd-MkKzNFQ{PDR:L3G+
B16 NH\JO5pEgXSxdH;4bYNqfHliYYPzZZk> NET6fVE1QCCqcoO= MUPDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W|ZTDCNVYh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOzJO69VS5? MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjNyNEO0OEc,OjJ|MESzOFQ9N2F-
HepG2 MYjDfZRwfG:6aXPpeJkh[XO|YYm= M4Pwd|Q5KGi{cx?= MYTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|Qh|ryPLh?= M1GyZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{M{C0N|Q1Lz5{MkOwOFM1PDxxYU6=
MCF7 NFfUeJZEgXSxdH;4bYNqfHliYYPzZZk> M3Tr[lQ5KGi{cx?= M4rTeWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFM2KM7:TT6= MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjNyNEO0OEc,OjJ|MESzOFQ9N2F-
HeLa NIG0O2NEgXSxdH;4bYNqfHliYYPzZZk> M1T1fFQ5KGi{cx?= MXLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0N{DPxE1w MmP5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ|MESzOFQoRjJ{M{C0N|Q1RC:jPh?=
SW1990 M37hTmN6fG:2b4jpZ4l1gSCjc4PhfS=> MknrOFghcHK| M3n3NGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNYOTl7MDDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPDVizszNMi=> M{XXfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{M{C0N|Q1Lz5{MkOwOFM1PDxxYU6=
SR M1\0fWN6fG:2b4jpZ4l1gSCjc4PhfS=> NHHUOlU1QCCqcoO= NEnt[nlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUWiClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBIUTVyIE2gNE4xOjN6IN88UU4> M{j3S|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{M{C1OVQ{Lz5{MkOwOVU1OzxxYU6=
NCI-H522 NUTwdJVsS3m2b4TvfIlkcXS7IHHzd4F6 NV\TZnJyPDhiaILz MYrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDOR2kuUDV{MjDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hPy5{ODFOwG0v MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjNyNUW0N{c,OjJ|MEW1OFM9N2F-
WHCO1 Mn;vRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MmHROFghcHK| M4PRcmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iV1jDU|Eh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEeuPUDPxE1w MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjN6MUO1OEc,OjJ|OEGzOVQ9N2F-
HaCaT MkD4R5l1d3O2YYTpZ{Bi[3Srdnn0fUBie3OjeR?= NV;TfZZlPzJiaILz NVTRfVRQS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhiS2GWIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjNizszNMi=> NECxemk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSwOVI6OCd-MkK0NFUzQTB:L3G+
L1210 MV3DfZRwe3SjdHnjJIFkfGm4aYT5JIF{e2G7 M2i1bFIh\GG7cx?= NIHWVZlEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhdW:3c3WgUFEzOTBiY3XscJMh[W[2ZYKgNkBl[Xm|IHL5JINwfWy2ZYKgZ492dnSncjDhcoFtgXOrczygTWM2OCB;IECuOFkh|ryPLh?= MorGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2MEWyPVAoRjJ{NEC1NlkxRC:jPh?=
HeLa M2noWmN6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= MmPZN{Bl[Xm| NHOzVmtEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjCzJIRigXNiYomgZ492dHSncjDjc5VvfGW{IHHuZYx6e2m|LDDJR|UxKD1iMD61OEDPxE1w MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjRyNUK5NEc,OjJ2MEWyPVA9N2F-
NCI-H460 NXL3NGdLS3m2b4P0ZZRq[yCjY4Tpeol1gSCjc4PhfS=> NUnnfotmPzJiaILz M1PReGN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kuUDR4MDDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOyEQvF2u Mo\GQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2MEWyPVAoRjJ{NEC1NlkxRC:jPh?=
HCT116 MXrDfZRwe3SjdHnjJIFkfGm4aYT5JIF{e2G7 MUK3NkBpenN? MojqR5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFEyPiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOEDPxE1w M4nkR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEC1NlkxLz5{MkSwOVI6ODxxYU6=
MCF7 Mme0R5l1d3O2YYTpZ{Bi[3Srdnn0fUBie3OjeR?= MV23NkBpenN? NHiwOIFEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUh|ryPLh?= MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjRyNUK5NEc,OjJ2MEWyPVA9N2F-
CEM NVLNdmZKS3m2b4P0ZZRq[yCjY4Tpeol1gSCjc4PhfS=> NXrFPI9POyCmYYnz M3ixXWN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOgZYZ1\XJiMzDkZZl{KGK7IHPveYx1\XJiY3;1cpRmeiCjbnHsfZNqeyxiSVO1NEA:KDF6IN88UU4> M1XvRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEC1NlkxLz5{MkSwOVI6ODxxYU6=
MGC803 M17I[mN6fG:2b4jpZ4l1gSCjc4PhfS=> NGj5SHQ1QCCqcoO= NULjTHYxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUeFOECzJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|LkSyJO69VS5? NWLDSYRDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0NFU3PDhpPkKyOFA2PjR6PD;hQi=>
Bcap37 MV7DfZRwfG:6aXPpeJkh[XO|YYm= M3nHeVQ5KGi{cx?= M{LxXmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGJk[XB|NzDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPS5|MzFOwG0v M{faXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEC1OlQ5Lz5{MkSwOVY1QDxxYU6=
SGC7901 M{TkSmN6fG:2b4jpZ4l1gSCjc4PhfS=> NFPpPHk1QCCqcoO= NVTvbnBpS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0eFN{mwNUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNz6xNUDPxE1w M2XoO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEC1OlQ5Lz5{MkSwOVY1QDxxYU6=
MCF7 NGfrUHFEgXSxdH;4bYNqfHliYYPzZZk> NX;Gfnk1PzJiaILz NEHvUnlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUA{NjVizszNMi=> MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjRyOUe3NUc,OjJ2MEm3O|E9N2F-
HepG2 MoLFR5l1d3SxeHnjbZR6KGG|c3H5 NXftPYxlPzJiaILz NYP6SopuS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDVizszNMi=> MlLzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2MEm3O|EoRjJ{NEC5O|cyRC:jPh?=
HCT116 NFrKbYVEgXSxdH;4bYNqfHliYYPzZZk> NID1Xlk4OiCqcoO= M{jke2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDFzNjDj[YxteyCjZoTldkA4OiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hPiEQvF2u NF\XfYU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSwPVc4OSd-MkK0NFk4PzF:L3G+
FOCUS MVfDfZRwfG:6aXPpeJkh[XO|YYm= NYHx[Y5PPzJiaILz MXLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDGU2NWWyClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gO{43KM7:TT6= MkCxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2MEm3O|EoRjJ{NEC5O|cyRC:jPh?=
Mahlavu MVjDfZRwfG:6aXPpeJkh[XO|YYm= MoPqO|IhcHK| MVzDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNZYht[X[3IHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAyOCEQvF2u NHvEU4o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSwPVc4OSd-MkK0NFk4PzF:L3G+
HuH7 MULDfZRwfG:6aXPpeJkh[XO|YYm= MWm3NkBpenN? MVnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIeWg4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCzNE44KM7:TT6= MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjRyOUe3NUc,OjJ2MEm3O|E9N2F-
K562 NV:2[ow3S3m2b4TvfIlkcXS7IHHzd4F6 MkPNR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT|U3OiClZXzsd{whUUN3MDC9JFIvPCEQvF2u NW\xPHlCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0NFk6PjdpPkKyOFA6QTZ5PD;hQi=>
COLO205 M2HrVWN6fG:2b4jpZ4l1gSCjc4PhfS=> MYnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDU2xQOjB3IHPlcIx{NCCLQ{WwJF0hPC5zNzFOwG0v NFm5c2Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSwPVk3Pyd-MkK0NFk6Pjd:L3G+
KM12 M1nJcGN6fG:2b4jpZ4l1gSCjc4PhfS=> NUD0NGUxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hU01zMjDj[YxteyxiSVO1NEA:KDhwM{Kg{txONg>? Ml;kQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2MEm5OlcoRjJ{NEC5PVY4RC:jPh?=
HCT116 NE\4S49EgXSxdH;4bYNqfHliYYPzZZk> MUTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMtKEmFNUCgQUA5NjVzIN88UU4> MofsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2MEm5OlcoRjJ{NEC5PVY4RC:jPh?=
HCT15 MXvDfZRwfG:6aXPpeJkh[XO|YYm= NG\QfJlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzNTDj[YxteyxiSVO1NEA:KDlwN{Gg{txONg>? MlH4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2MEm5OlcoRjJ{NEC5PVY4RC:jPh?=
HT-29 NGfxRnpEgXSxdH;4bYNqfHliYYPzZZk> NXK3ZlhIS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUFRvMkmgZ4VtdHNuIFnDOVAhRSBzMD6yJO69VS5? NH\sXHY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSwPVk3Pyd-MkK0NFk6Pjd:L3G+
HCC2998 M3zaRmN6fG:2b4jpZ4l1gSCjc4PhfS=> NHLte3VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS0N{OUm4JINmdGy|LDDJR|UxKD1iMUOuOUDPxE1w M33KT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEC5PVY4Lz5{MkSwPVk3PzxxYU6=
PC3 MXfBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NEjuRmU1QCCqcoO= NXnsc|MxSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEmFNUCgQUAzNjFizszNMi=> MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR{NE[xOEc,OjJ2MkS2NVQ9N2F-
MOLT4 NXvicId1SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MlPSOFghcHK| MYLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2RTGS0JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBKSzVyIE2gN{4zKM7:TT6= MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR{NE[xOEc,OjJ2MkS2NVQ9N2F-
MCF7 M2rhS2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NVTmS|ZYOTR2IHjydy=> NYC1fG0zSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9vKGGodHXyJFE1PCCqcoOgZpkh[3K7c4ThcEB3cW:uZYSgd5RicW6rbnegcYV1cG:mLDDJR|UxKD1iND63JO69VS5? NHTYVVM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkS1NFE{Oid-MkK0OVAyOzJ:L3G+
HT-29 M1T0OWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M{C1WVE1PCCqcoO= MX\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiWLUK5JINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IEG0OEBpenNiYomgZ5J6e3SjbDD2bY9t\XRic4ThbY5qdmdibXX0bI9lNCCLQ{WwJF0hPy5|IN88UU4> Mn3xQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2NUCxN|IoRjJ{NEWwNVMzRC:jPh?=
MDA-MB-231 NHXaTIFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NEHyVmsyPDRiaILz NWrCSpdbSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IEG0OEBpenNiYomgZ5J6e3SjbDD2bY9t\XRic4ThbY5qdmdibXX0bI9lNCCLQ{WwJF0hQS54IN88UU4> MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR3MEGzNkc,OjJ2NUCxN|I9N2F-
PC9 NX3qVXduS3m2b4TvfIlkcXS7IHHzd4F6 NWTZRlZiPDhiaILz NFrtXlFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzliY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI{NjR5IN88UU4> MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR6M{[wPEc,OjJ2OEO2NFg9N2F-
HCT116 Ml25R5l1d3SxeHnjbZR6KGG|c3H5 MmLLOFghcHK| NWTBUlJJS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|MT63NkDPxE1w M4TIOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEizOlA5Lz5{MkS4N|YxQDxxYU6=
A549 NXS5d|FMS3m2b4TvfIlkcXS7IHHzd4F6 NHnCZVE1QCCqcoO= NH31cVNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{PS5yNTFOwG0v NFvUeog9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkS4N|YxQCd-MkK0PFM3ODh:L3G+
HepG2 MWnDfZRwfG:6aXPpeJkh[XO|YYm= MlTIOFghcHK| M3LuUWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1Pi5|MTFOwG0v MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR6M{[wPEc,OjJ2OEO2NFg9N2F-
A375 NVLUbWxIS3m2b4TvfIlkcXS7IHHzd4F6 NFrWZ5Y1QCCqcoO= Mke2R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVM4PSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOFYvPTVizszNMi=> NWPOUW11RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0PFM3ODhpPkKyOFg{PjB6PD;hQi=>
SKHEP1 NFHHbJJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2HQPFQ5KGi{cx?= NHrL[odIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBUU0iHUEGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiR1m1NEA:KDZwMzFOwG0v MkXyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3MUK5NFgoRjJ{NUGyPVA5RC:jPh?=
NCI-H460 MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWLh[FVRPDhiaILz M4rOVWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNE[wJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCVUlKgZZN{[XluIFfJOVAhRSB4LkWg{txONg>? NVX4W|FORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1NVI6ODhpPkKyOVEzQTB6PD;hQi=>
BxPC3 NGnMRlVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoHVOFghcHK| NX\FR4Q3T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hSniSQ{OgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiR1m1NEA:KDhwMjFOwG0v Mn;XQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3MUK5NFgoRjJ{NUGyPVA5RC:jPh?=
MSC NFjLUZdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXW0PEBpenN? NGK4cGNIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBOW0NiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFgvQTJizszNMi=> MkK3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3MUK5NFgoRjJ{NUGyPVA5RC:jPh?=
IGROV1 MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3;PWlQ5KGi{cx?= NInuVGJIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBKT1KRVkGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiR1m1NEA:KDlwMTFOwG0v MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjVzMkmwPEc,OjJ3MUK5NFg9N2F-
DU145 M3W2dmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWW0PEBpenN? NGCycopIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBFXTF2NTDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hQS5|NzFOwG0v NXXHXlY4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1NVI6ODhpPkKyOVEzQTB6PD;hQi=>
HUVEC M1zOSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXqxNIlEPDhiaILz M{\MVGdzd3e2aDDpcohq[mm2aX;uJI9nKEiXVlXDJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCVUlKgZZN{[XluIFfJOVAhRSB7LkeyJO69VS5? NInKdpY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkWxNlkxQCd-MkK1NVI6ODh:L3G+
HCT116 NESxNphIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1zGXVQ5KGi{cx?= MoDkS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTGNVOTF4IHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEeLNUCgQUA6NjlizszNMi=> M{jpUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUGyPVA5Lz5{MkWxNlkxQDxxYU6=
MCF7 Mm\oS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYDzOW0zPDhiaILz NX24TYo5T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hVUOINzDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hQS57IN88UU4> M1rpcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUGyPVA5Lz5{MkWxNlkxQDxxYU6=
OVCAR5 M3z3cWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH7QcXU1QCCqcoO= M3vTTWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG9XS0GUNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hOjBizszNMi=> NU\5dZNlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1NVI6ODhpPkKyOVEzQTB6PD;hQi=>
HCT15 MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2njNVQ5KGi{cx?= MnnkS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTGNVOTViY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFIyKM7:TT6= NILCVFM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkWxNlkxQCd-MkK1NVI6ODh:L3G+
PC3 NWnlOoZST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWC0PEBpenN? NYPD[VBET3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hWEN|IHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEeLNUCgQUAzOSEQvF2u MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjVzMkmwPEc,OjJ3MUK5NFg9N2F-
MIAPaCa2 M3L0UWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWKwOJMxPDhiaILz NIPPcFlIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBOUUGSYVPhNkBk\WyuczDh[pRmeiB2ODDodpMh[nliU2LCJIF{e2G7LDDHTVUxKD1iM{Cg{txONg>? M3;CcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUGyPVA5Lz5{MkWxNlkxQDxxYU6=
K562 NWXHTXFFS3m2b4TvfIlkcXS7IHHzd4F6 NWLrUlA2PDhiaILz M3\qVGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGs2PjJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIvOSEQvF2u Mk\rQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3M{ezOlIoRjJ{NUO3N|YzRC:jPh?=
KB MnrCR5l1d3SxeHnjbZR6KGG|c3H5 NIi3Rnc1QCCqcoO= MVvDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLRkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNj64JO69VS5? Mlz4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3M{ezOlIoRjJ{NUO3N|YzRC:jPh?=
KB/VCR Mk\uR5l1d3SxeHnjbZR6KGG|c3H5 MXq0PEBpenN? MoPtR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT2IwXkOUIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{Oy52IN88UU4> MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjV|N{O2Nkc,OjJ3M{ezOlI9N2F-
SW620 NV:0OGxiSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MVi3NkBpenN? NVvYfZVFSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|YzOCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOk43QCEQvF2u NGqyc4g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkW1OVE2Oid-MkK1OVUyPTJ:L3G+
MIAPaCa2 MXrBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NGPq[444OiCqcoO= MmnIRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPSVHQZWNiOiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVEvPjdizszNMi=> M2i4XFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUW1NVUzLz5{MkW1OVE2OjxxYU6=
HeLa MVfBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NV3meml[PzJiaILz NYrudnJISW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOE46OyEQvF2u MlHDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3NUWxOVIoRjJ{NUW1NVUzRC:jPh?=
WI38 NWnMXHB5SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MWW3NkBpenN? M1rpO2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iV1mzPEBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMkSuOlYh|ryPLh?= Mn;DQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3NUWxOVIoRjJ{NUW1NVUzRC:jPh?=
A549 Ml7MR5l1d3SxeHnjbZR6KGG|c3H5 Ml;1OFghcHK| NFvZXoJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGK7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB3Lk[0JO69VS5? MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjV5OUe4NEc,OjJ3N{m3PFA9N2F-
SGC7901 MXTDfZRwfG:6aXPpeJkh[XO|YYm= MlTsOFghcHK| NGPB[XlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUT0N5OUCxJINmdGy|IHL5JIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC2MlA1KM7:TT6= NXW5[pllRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1O|k4QDBpPkKyOVc6PzhyPD;hQi=>
MDA-MB-231 MnvRR5l1d3SxeHnjbZR6KGG|c3H5 NWizc3MxPDhiaILz M2Hud2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj2yN|Eh[2WubIOgZpkh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE{NjZ3IN88UU4> NEO5XY09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkW3PVc5OCd-MkK1O|k4QDB:L3G+
QGY7701 Ml34R5l1d3SxeHnjbZR6KGG|c3H5 Ml\0OFghcHK| M4POcGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHFIYTd5MEGgZ4VtdHNiYomgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG0MlMh|ryPLh?= Mn7lQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3N{m3PFAoRjJ{NUe5O|gxRC:jPh?=
SW480 MU\DfZRwfG:6aXPpeJkh[XO|YYm= MYC0PEBpenN? NGPEUlJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUXzR6MDDj[YxteyCkeTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUWuO|Eh|ryPLh?= NFjhR5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkW3PVc5OCd-MkK1O|k4QDB:L3G+
HeLa M3XCfGN6fG:2b4jpZ4l1gSCjc4PhfS=> M3vSOFQ5KGi{cx?= MkizR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{BjgSCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTZwM{Kg{txONg>? MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjV5OUe4NEc,OjJ3N{m3PFA9N2F-
L02 MWPDfZRwfG:6aXPpeJkh[XO|YYm= M4LuVFQ5KGi{cx?= NEPTWZJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBNODJiY3XscJMh[nliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR4LkW3JO69VS5? MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjV5OUe4NEc,OjJ3N{m3PFA9N2F-
SH-SY5Y M2nsdGN6fG:2b4jpZ4l1gSCjc4PhfS=> Mn3SO|IhcHK| MXnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTTE1UYTW\IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyNjB7IN88UU4> M2Pq[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{Nki3O|Q2Lz5{Mk[4O|c1PTxxYU6=
L929 NViyc2tXS3m2b4TvfIlkcXS7IHHzd4F6 MV:3NkBpenN? NHjrPY9EgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBNQTJ7IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyNjN6IN88UU4> M{f2elxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{Nki3O|Q2Lz5{Mk[4O|c1PTxxYU6=
A549 M{fHfWN6fG:2b4jpZ4l1gSCjc4PhfS=> MnOzO|IhcHK| M1fGVWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFgvQDNizszNMi=> M{fCdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{Nki3O|Q2Lz5{Mk[4O|c1PTxxYU6=
DU145 MYHDfZRwfG:6aXPpeJkh[XO|YYm= MUS3NkBpenN? MnXSR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSHUyPDViY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEzNjN{IN88UU4> MnewQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ4OEe3OFUoRjJ{Nki3O|Q2RC:jPh?=
SGC7901 Mm\DR5l1d3SxeHnjbZR6KGG|c3H5 MVe3NkBpenN? M{jpXmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNISzd7MEGgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF2LkS5JO69VS5? NFOx[4k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mk[4O|c1PSd-MkK2PFc4PDV:L3G+
HeLa MkjiR5l1d3SxeHnjbZR6KGG|c3H5 NVjWTlRjPzJiaILz MlvlR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUvQTlizszNMi=> MmT1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ4OEe3OFUoRjJ{Nki3O|Q2RC:jPh?=
HepG2 MXfDfZRwfG:6aXPpeJkh[XO|YYm= M2\welczKGi{cx?= NVLrRlI{S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN{LkKyJO69VS5? M2nFPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{Nki3O|Q2Lz5{Mk[4O|c1PTxxYU6=
NCI-H460 Mly1R5l1d3SxeHnjbZR6KGG|c3H5 NYniZ4ZqPzJiaILz NX;sZYdzS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVkOLLVi0OlAh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKuOEDPxE1w MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjd{N{S0OUc,OjJ5Mke0OFU9N2F-
BGC823 MkjvR5l1d3SxeHnjbZR6KGG|c3H5 Ml;LO|IhcHK| NH\CcnZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBDT0N6MkOgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDRwNTFOwG0v MmrlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ5Mke0OFUoRjJ{N{K3OFQ2RC:jPh?=
HepG2 MoDLR5l1d3SxeHnjbZR6KGG|c3H5 M1j4bVczKGi{cx?= MknVR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQvQCEQvF2u MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjd{N{S0OUc,OjJ5Mke0OFU9N2F-
SGC7901 NFruWYpEgXSxdH;4bYNqfHliYYPzZZk> MVG3NkBpenN? MV7DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTS2M4QTBzIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA3NjNizszNMi=> NGHJUlA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkeyO|Q1PSd-MkK3Nlc1PDV:L3G+
MCF7 MX7DfZRwfG:6aXPpeJkh[XO|YYm= M2e2VFczKGi{cx?= M3T3fmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEzNjVizszNMi=> M{PYflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{K3OFQ2Lz5{MkeyO|Q1PTxxYU6=
KB NXmwdGtvS3m2b4TvfIlkcXS7IHHzd4F6 NUnQcFVIPzJiaILz NU\zXFdLS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hU0JiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFgvOjhizszNMi=> M{\jfFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{S5NVkzLz5{Mke0PVE6OjxxYU6=
MCF7 M2fwRWN6fG:2b4jpZ4l1gSCjc4PhfS=> MUe3NkBpenN? MVjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOE4zKM7:TT6= M2fPcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{S5NVkzLz5{Mke0PVE6OjxxYU6=
CNE2 NXnySXlrS3m2b4TvfIlkcXS7IHHzd4F6 NFznZ5g4OiCqcoO= NEP6XY9EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBEVkV{IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPS5zIN88UU4> MlrUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ5NEmxPVIoRjJ{N{S5NVkzRC:jPh?=
GLC82 NULNXWh5S3m2b4TvfIlkcXS7IHHzd4F6 NYHSRo4zPzJiaILz NIjOUmxEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBIVEN6MjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTdwNDFOwG0v NVHuR3VbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK3OFkyQTJpPkKyO|Q6OTl{PD;hQi=>
MGC803 M4LrWmN6fG:2b4jpZ4l1gSCjc4PhfS=> NHXJNXA4OiCqcoO= NEf4S2dEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOT0N6MEOgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF6LkWg{txONg>? MoDxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ5NEmxPVIoRjJ{N{S5NVkzRC:jPh?=
MCF7 MWLBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MUO3NkBpenN? NV:wdlVSSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDjdpl{fGGuII\pc4xmfCC|dHHpcolv\yCvZYToc4QtKEmFNUCgQUA1NjdizszNMi=> M1HwWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{[1PFk4Lz5{Mke2OVg6PzxxYU6=
HT-29 NHr1Z4hCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NEHnS2M4OiCqcoO= NXPBcVFPSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bi\nSncjC3NkBpenNiYomgZ5J6e3SjbDD2bY9t\XRic4ThbY5qdmdibXX0bI9lNCCLQ{WwJF0hPy5|IN88UU4> MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjd4NUi5O{c,OjJ5NkW4PVc9N2F-
MDA-MB-231 NVPoc5VESW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NFv5R2M4OiCqcoO= NXribVJwSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy|IHHmeIVzKDd{IHjyd{BjgSClconzeIFtKH[rb3zleEB{fGGrbnnu[{Bu\XSqb3SsJGlEPTBiPTC5MlYh|ryPLh?= MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjd4NUi5O{c,OjJ5NkW4PVc9N2F-
HT1080 MV3DfZRwfG:6aXPpeJkh[XO|YYm= M2rKW2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhVOTB6MDDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlA3KM7:TT6= NUH3[I8xRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NFE3PDRpPkKyPFAyPjR2PD;hQi=>
A375-S2 NEm0UodEgXSxdH;4bYNqfHliYYPzZZk> MmrMR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVM4PS2VMjDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC5MlkzKM7:TT6= NEH1TYs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkiwNVY1PCd-MkK4NFE3PDR:L3G+
HeLa NHHZb2ZEgXSxdH;4bYNqfHliYYPzZZk> NWrjTHhyS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNE4{PiEQvF2u M{W2[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OECxOlQ1Lz5{MkiwNVY1PDxxYU6=
HepG2 MmnrR5l1d3SxeHnjbZR6KGG|c3H5 MVnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMD60OUDPxE1w NF3udYU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkiwNVY1PCd-MkK4NFE3PDR:L3G+
BGC823 M{fOPGN6fG:2b4jpZ4l1gSCjc4PhfS=> M2rUUmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGJISzh{MzDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOU43PSEQvF2u MnXlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEG2OFQoRjJ{OECxOlQ1RC:jPh?=
Hep2 NIDDd3pEgXSxdH;4bYNqfHliYYPzZZk> MUTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZAzKGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ2LkW4JO69VS5? Ml\MQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEG2OFQoRjJ{OECxOlQ1RC:jPh?=
MCF7 MUjDfZRwfG:6aXPpeJkh[XO|YYm= MXrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ2LkW4JO69VS5? NF[zO2Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkiwNVY1PCd-MkK4NFE3PDR:L3G+
A549 NFPEPVNEgXSxdH;4bYNqfHliYYPzZZk> MlnGR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|MT61NkDPxE1w NVn1N2xtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NFE3PDRpPkKyPFAyPjR2PD;hQi=>
MDA231 M1HoO2N6fG:2b4jpZ4l1gSCjc4PhfS=> M17OO2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSTJ|MTDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzNU42PyEQvF2u MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjhyMU[0OEc,OjJ6MEG2OFQ9N2F-
PC3 NWD1OVloS3m2b4TvfIlkcXS7IHHzd4F6 NV\zO2pbS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWEN|IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEO1Mlc2KM7:TT6= M2KyUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OECxOlQ1Lz5{MkiwNVY1PDxxYU6=
PC3M NWPYfWgyS3m2b4TvfIlkcXS7IHHzd4F6 NXLTcpRUPDhiaILz M4LyUGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHBEO01iY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIzNjZ|IN88UU4> MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjhyOUW1PEc,OjJ6MEm1OVg9N2F-
A549 NXvueZg4S3m2b4TvfIlkcXS7IHHzd4F6 NVvJcnUzPDhiaILz M2\sc2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFM2NjRzIN88UU4> NUS2c2NnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NFk2PThpPkKyPFA6PTV6PD;hQi=>
MKN45 MVLDfZRwfG:6aXPpeJkh[XO|YYm= M1XZdVQ5KGi{cx?= MoXxR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWtPPDViY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQyNjd|IN88UU4> NE\hfnQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkiwPVU2QCd-MkK4NFk2PTh:L3G+
HepG2 NYPaVHBLS3m2b4TvfIlkcXS7IHHzd4F6 MnPVOFghcHK| MnrKR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQ3Njh|IN88UU4> NUTxe2ltRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NFk2PThpPkKyPFA6PTV6PD;hQi=>
LoVo NEDVNYFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MnHuOFghcHK| NGm5e5hCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFzvWo8h[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOuN{DPxE1w NVPxTnE5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4OFA1QTNpPkKyPFQxPDl|PD;hQi=>
A549 NXzze444SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NWT3ZnNOPDhiaILz NXXQR4ZTSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNk45KM7:TT6= NFXXO3I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mki0NFQ6Oyd-MkK4OFA1QTN:L3G+
MCF7 NX24WXl3SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M1zJTFQ5KGi{cx?= M{LKemFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMU[uNkDPxE1w MoG1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6NEC0PVMoRjJ{OESwOFk{RC:jPh?=
IOSE-144 NFXncmxCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NYWzR3hRPDhiaILz M{TYZmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSV;TSU0yPDRiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI2NjZizszNMi=> Ml73QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6NEC0PVMoRjJ{OESwOFk{RC:jPh?=
CAMA1 NGP6d5JEgXSxdH;4bYNqfHliYYPzZZk> MoSwO|IhcHK| M2r4VmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNCVUFzIHPlcIx{KGmwY4XiZZRm\CCob4KgO|IhcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFEvOjhizszNMi=> NULYfY5RRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4Olc4ODdpPkKyPFY4PzB5PD;hQi=>
MCF7 NYnxfJhNS3m2b4TvfIlkcXS7IHHzd4F6 NW\iVnJLPzJiaILz MojhR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{BqdmO3YnH0[YQh\m:{IEeyJIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCzMlUh|ryPLh?= MnvpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6Nke3NFcoRjJ{OE[3O|A4RC:jPh?=
HepG2 NVjnOGdlS3m2b4TvfIlkcXS7IHHzd4F6 NF7EdZc4OiCqcoO= Mn\XR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMhcW6ldXLheIVlKG[xcjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gOU44KM7:TT6= MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh4N{ewO{c,OjJ6Nke3NFc9N2F-
FOCUS M1fDRWN6fG:2b4jpZ4l1gSCjc4PhfS=> MVm3NkBpenN? Mlz6R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSm9EXVNiY3XscJMhcW6ldXLheIVlKG[xcjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gO{43QSEQvF2u Mo\wQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6Nke3NFcoRjJ{OE[3O|A4RC:jPh?=
T47D MWrDfZRwfG:6aXPpeJkh[XO|YYm= MVe3NkBpenN? Mnf3R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWFQ4TCClZXzsd{BqdmO3YnH0[YQh\m:{IEeyJIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTC4MlkyKM7:TT6= NH3nRoo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mki2O|cxPyd-MkK4Olc4ODd:L3G+
MV MUnDfZRwfG:6aXPpeJkh[XO|YYm= MUO3NkBpenN? MnrWR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUXYh[2WubIOgbY5kfWKjdHXkJIZweiB5MjDodpMh[nliU2LCJIF{e2G7LDDJR|UxKD1iOT65O{DPxE1w MnKwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6Nke3NFcoRjJ{OE[3O|A4RC:jPh?=
HCT116 MkXnR5l1d3SxeHnjbZR6KGG|c3H5 NFG2VYU4OiCqcoO= NWLNPVN4S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHnuZ5Vj[XSnZDDmc5IhPzJiaILzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDF6Lkeg{txONg>? MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh4N{ewO{c,OjJ6Nke3NFc9N2F-
MFE296 NXfV[WpCS3m2b4TvfIlkcXS7IHHzd4F6 NF;TO5M4OiCqcoO= M37ZVGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1HTTJ7NjDj[YxteyCrbnP1ZoF1\WRiZn;yJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUA{OC54ODFOwG0v NH;QdIc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mki2O|cxPyd-MkK4Olc4ODd:L3G+
HuH7 MWXDfZRwfG:6aXPpeJkh[XO|YYm= NV\hfZZWPzJiaILz NHT3PZJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJfUh5IHPlcIx{KGmwY4XiZZRm\CCob4KgO|IhcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFMxNjdizszNMi=> NHq1ZZA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mki2O|cxPyd-MkK4Olc4ODd:L3G+
BT20 MX;DfZRwfG:6aXPpeJkh[XO|YYm= MnjFO|IhcHK| NIfBV4hEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBDXDJyIHPlcIx{KGmwY4XiZZRm\CCob4KgO|IhcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFQ4NjNizszNMi=> MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh4N{ewO{c,OjJ6Nke3NFc9N2F-
COLO320 NFLFZWNEgXSxdH;4bYNqfHliYYPzZZk> MmfPO|IhcHK| Mn;HR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR29NVzN{MDDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKH[rYXLpcIl1gSCjZoTldkA4OiCqcoOgZpkhX1OWLUGgZZN{[XluIFnDOVAhRSBzMj61JO69VS5? NE\XXYU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mkm1OVA6PSd-MkK5OVUxQTV:L3G+
MCF7 NVr3eJd3S3m2b4TvfIlkcXS7IHHzd4F6 M4PvSFczKGi{cx?= M1rmS2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JINzgXO2YXygeolwdGW2IIP0ZYlvcW6pLDDJR|UxKD1iND63JO69VS5? NF3yO4k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mkm1PVIxPSd-MkK5OVkzODV:L3G+
HT-29 M4\2WmN6fG:2b4jpZ4l1gSCjc4PhfS=> MXi3NkBpenN? NEnGUpREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXC1{OTDj[YxteyCjZoTldkA4OiCqcoOgZpkh[3K7c4ThcEB3cW:uZYSgd5RicW6rbnesJGlEPTBiPTC3MlMh|ryPLh?= M2Hh[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OUW5NlA2Lz5{Mkm1PVIxPTxxYU6=
MDA-MB-231 NW\xXllmS3m2b4TvfIlkcXS7IHHzd4F6 M3TGcVczKGi{cx?= MVrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy|IHHmeIVzKDd{IHjyd{BjgSClconzeIFtKH[rb3zleEB{fGGrbnnu[{whUUN3MDC9JFkvPiEQvF2u MmS0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ7NUmyNFUoRjJ{OUW5NlA2RC:jPh?=
HL60 M2LT[WN6fG:2b4jpZ4l1gSCjc4PhfS=> MlPGO|IhcHK| NYjwcmdMS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEx4MDDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5yNjFOwG0v M{LEW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OUW5OVE5Lz5{Mkm1PVUyQDxxYU6=
HeLa NFXHXXREgXSxdH;4bYNqfHliYYPzZZk> MV63NkBpenN? MUjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlI5KM7:TT6= NVnU[JBiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5OVk2OThpPkKyPVU6PTF6PD;hQi=>
U937 Mn2yR5l1d3SxeHnjbZR6KGG|c3H5 MU[3NkBpenN? Ml;IR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWVk{PyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNU4xPyEQvF2u M2PI[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OUW5OVE5Lz5{Mkm1PVUyQDxxYU6=
colon cancer NIrwPGFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M1vnNlQ5KGi{cx?= NXywSVVoSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDjc4xwdiClYX7j[ZIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IHPlcIwh[2:3boTpcoch[W6jbInzbZMtKEeLNUCgQUA5NjRizszNMi=> NH;hcnE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mkm5OVYzOSd-MkK5PVU3OjF:L3G+
leukemia MVfBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MUK0PEBpenN? MWXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKGyndXvlcYliKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDj[YxtKGOxdX70bY5oKGGwYXz5d4l{NCCJSUWwJF0hOTVwMTFOwG0v Mmq2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ7OUW2NlEoRjJ{OUm1OlIyRC:jPh?=
prostate cancer MXzBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M1zpO|Q5KGi{cx?= M2PjemFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5icILvd5RifGViY3HuZ4VzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDj[YxtKGOxdX70bY5oKGGwYXz5d4l{NCCJSUWwJF0hOjJwNzFOwG0v M3m5PVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OUm1OlIyLz5{Mkm5OVYzOTxxYU6=
renal cancer MUnBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M4rGUVQ5KGi{cx?= NWjMXYtMSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDy[Y5idCClYX7j[ZIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IHPlcIwh[2:3boTpcoch[W6jbInzbZMtKEeLNUCgQUA1PS54IN88UU4> NWnFdFFKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5PVU3OjFpPkKyPVk2PjJzPD;hQi=>
HeLa MnnHR5l1d3SxeHnjbZR6KGG|c3H5 MXm0PEBpenN? MmTrR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gPU42KM7:TT6= NUO4b45rRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwNFI6OjRpPkKzNFAzQTJ2PD;hQi=>
MNK45 MWPDfZRwfG:6aXPpeJkh[XO|YYm= M{TPfFQ5KGi{cx?= MUDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNUms1PSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVIh|ryPLh?= NGPTXG89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{CwNlkzPCd-MkOwNFI6OjR:L3G+
HepG2 NGHR[nRCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NG\KfWc1QCCqcoO= MW\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEincFeyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgcYV1cG:mLDDJR|UxKD1iMT6zJO69VS5? MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzBzOEC5Okc,OjNyMUiwPVY9N2F-
BGC823 NVf3UnBuSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MYK0PEBpenN? MlK2RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCER1O4NlMh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBu\XSqb3SsJGlEPTBiPTCxMlUzKM7:TT6= MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzBzOEC5Okc,OjNyMUiwPVY9N2F-
SW1116 NHL2b29CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NEOwflI1QCCqcoO= M1r3UmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2exNVE3KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gNk41OSEQvF2u M1n2dFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEG4NFk3Lz5{M{CxPFA6PjxxYU6=
HeLa NH7qVnJCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NV3X[VJGPDhiaILz NYrSd4RpSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gN{4zPSEQvF2u MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzBzOEC5Okc,OjNyMUiwPVY9N2F-
A549 M{PiT2N6fG:2b4jpZ4l1gSCjc4PhfS=> MmrNOFghcHK| MkXYR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliU2LCJIF{e2G7LDDJR|UxKD1iND6yNUDPxE1w M3rpT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MES0N|cxLz5{M{C0OFM4ODxxYU6=
HT1080 M3zz[WN6fG:2b4jpZ4l1gSCjc4PhfS=> Ml3SOFghcHK| MWLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWFExQDBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE2NjJizszNMi=> M4rIZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|ME[3OVQ6Lz5{M{C2O|U1QTxxYU6=
HCT116 NUO2NpZIS3m2b4TvfIlkcXS7IHHzd4F6 NYPvVGRKPDhiaILz NEPsUpBEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzMU[gZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN4LkSg{txONg>? MoDnQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyNke1OFkoRjJ|ME[3OVQ6RC:jPh?=
2008 MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVHHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjCyNFA5KGOnbHzzJIJ6KGO{eYP0ZYwhfmmxbHX0JIF{e2G7LDDJR|UxKD1iND6yJO69VS5? M2Xr[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEe1OFE1Lz5{M{C3OVQyPDxxYU6=
Vero MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnO3S5Jwf3SqIHnubIljcXSrb36gc4Yh[W[{aXPhckBoemWnbjDtc45s\XliVnXyc{Bk\WyuczDifUBkenm|dHHsJJZqd2yndDDhd5NigSxiSVO1NEA:KDRwNTFOwG0v MkPJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyN{W0NVQoRjJ|MEe1OFE1RC:jPh?=
A2780 MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnvjS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gRVI4QDBiY3XscJMh[nliY4L5d5RidCC4aX;s[ZQh[XO|YYmsJGlEPTBiPTC1MlEh|ryPLh?= NVPXSZYxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwO|U1OTRpPkKzNFc2PDF2PD;hQi=>
C13 MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXnHdo94fGhiaX7obYJqfGmxbjDv[kBkTESSLYLld4l{fGGwdDDoeY1idiCFMUOgZ4VtdHNiYomgZ5J6e3SjbDD2bY9t\XRiYYPzZZktKEmFNUCgQUA5NjVizszNMi=> M4i3T|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEe1OFE1Lz5{M{C3OVQyPDxxYU6=
A2780/CP70 NWfuUYxOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFi3c3hIem:5dHigbY5pcWKrdHnvckBw\iClRFTQMZJme2m|dHHueEBpfW2jbjDBNlc5OC:FUEewJINmdGy|IHL5JINzgXO2YXygeolwdGW2IHHzd4F6NCCLQ{WwJF0hOTJwMzFOwG0v M{PTb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEe1OFE1Lz5{M{C3OVQyPDxxYU6=
MSC Mn;sS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnvtOFghcHK| MmjuS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUXNEKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGdKPTBiPTCwMlAxOSEQvF2u M2rhO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEm0PVkzLz5{M{C5OFk6OjxxYU6=
MSC MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGLuUHY1QCCqcoO= NID2W|ZIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBOW0NiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhXEeLIE2gNE4xODFizszNMi=> M4HDZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEm0PVkzLz5{M{C5OFk6OjxxYU6=
BxPC3 MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1LSS|Q5KGi{cx?= MojOS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gRphRSzNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFAvODB{OTFOwG0v NX7kVVBGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwPVQ6QTJpPkKzNFk1QTl{PD;hQi=>
HUVEC MljKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWL4enNiPDhiaILz M2j2PGdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGhWXkWFIHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEeLNUCgQUAxNjByM{[g{txONg>? NXvSNIxqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwPVQ6QTJpPkKzNFk1QTl{PD;hQi=>
SKHEP1 M1PQNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIjJenA1QCCqcoO= NU[wSXljT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hW0uKRWCxJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCVUlKgZZN{[XluIFfJOVAhRSByLkCwO|Yh|ryPLh?= MojvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyOUS5PVIoRjJ|MEm0PVkzRC:jPh?=
IGROV1 NY\SSXJvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYS0PEBpenN? NUn6WVY1T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hUUeUT2[xJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCVUlKgZZN{[XluIFfJOVAhRSByLkCwPFEzKM7:TT6= NXHxVlY5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwPVQ6QTJpPkKzNFk1QTl{PD;hQi=>
BxPC3 NHrCOZZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIexO3U1QCCqcoO= NYHOT3pXT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hSniSQ{OgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiVFfJJF0hOC5yMEi0JO69VS5? NIW4SHc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C5OFk6Oid-MkOwPVQ6QTJ:L3G+
HCT116 M2LDPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYS0PEBpenN? NHHKbnFIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBJS1RzMU[gZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiR1m1NEA:KDBwMEC4PEDPxE1w NXfNXppmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwPVQ6QTJpPkKzNFk1QTl{PD;hQi=>
PC3 Mof5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1zlO|Q5KGi{cx?= NFjqVHBIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBRSzNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFAvODFyNEWg{txONg>? NWHpOIZWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwPVQ6QTJpPkKzNFk1QTl{PD;hQi=>
MCF7 MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHr6bWY1QCCqcoO= MlPTS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBIUTVyIE2gNE4xOTR3IN88UU4> MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzB7NEm5Nkc,OjNyOUS5PVI9N2F-
DU145 NF3iU4tIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1;aeFQ5KGi{cx?= NIK1UIJIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBFXTF2NTDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hOC5yMjFOwG0v M3nrSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEm0PVkzLz5{M{C5OFk6OjxxYU6=
HCT15 MmfUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmHmOFghcHK| NGPSdnVIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBJS1RzNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hOC5yMkGxJO69VS5? NHLzVIw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C5OFk6Oid-MkOwPVQ6QTJ:L3G+
OVCAR5 MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUfKfY9DPDhiaILz Ml7zS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gU3ZESVJ3IHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEeLNUCgQUAxNjB{NkSg{txONg>? NVLWPZg5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwPVQ6QTJpPkKzNFk1QTl{PD;hQi=>
MIAPaCa2 M4TiZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVXnOVNRPDhiaILz M4HwfWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG1KSVCjQ3GyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCVUlKgZZN{[XluIFfJOVAhRSByLkCzNFYh|ryPLh?= M4HRSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEm0PVkzLz5{M{C5OFk6OjxxYU6=
NHDF Mlm3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUHRXW57PDhiaILz NVr1SJNIT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hVkiGRjDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hOC5yNkKwNkDPxE1w NEPVNZc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C5OFk6Oid-MkOwPVQ6QTJ:L3G+
U251 NYLvbVE2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2TUeVQ5KGi{cx?= M1jrPWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJHUzPTFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFAvODZ7NjFOwG0v NFHwNWM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C5OFk6Oid-MkOwPVQ6QTJ:L3G+
NHDF MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mlv1OFghcHK| M3LaZWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG5JTEZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhXEeLIE2gNE4yKM7:TT6= MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzB7NEm5Nkc,OjNyOUS5PVI9N2F-
MIAPaCa2 NX;aWW43T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnK2OFghcHK| NHnEdJJIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBOUUGSYVPhNkBk\WyuczDh[pRmeiB2ODDodpMh[nliU2LCJIF{e2G7LDDUS2khRSByLkGg{txONg>? NIrKbWc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C5OFk6Oid-MkOwPVQ6QTJ:L3G+
HUVEC NVfvUWVxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4TuTFQ5KGi{cx?= NUX4VIdxT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hUFWYRVOgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiVFfJJF0hOC5zIN88UU4> NVu1[XJZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwPVQ6QTJpPkKzNFk1QTl{PD;hQi=>
OVCAR5 M1XnRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHHpU3A1QCCqcoO= M3;r[mdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG9XS0GUNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCWR1mgQUAxNjFizszNMi=> MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzB7NEm5Nkc,OjNyOUS5PVI9N2F-
HL-60(TB) MljzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NViyRnYzPDhiaILz NUjHXoRzT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hUExvNkCoWGIqKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGdKPTBiPTCwMlEh|ryPLh?= NVfROWpVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwPVQ6QTJpPkKzNFk1QTl{PD;hQi=>
HL-60(TB) MmLqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHi4dZo1QCCqcoO= NX\WWldyT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hUExvNkCoWGIqKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJHRIUSB;IECuNUDPxE1w MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzB7NEm5Nkc,OjNyOUS5PVI9N2F-
U251 NIGxcpRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYq2e4x4PDhiaILz NE\PXIxIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBWOjVzIHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKFSJSTC9JFAvOSEQvF2u NUHlOndFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwPVQ6QTJpPkKzNFk1QTl{PD;hQi=>
DU145 NFnGZVBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVS0PEBpenN? Ml7rS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gSHUyPDViY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhXEeLIE2gNE4yKM7:TT6= MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzB7NEm5Nkc,OjNyOUS5PVI9N2F-
SKHEP1 M3\Z[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEXIOJQ1QCCqcoO= MojqS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gV2tJTVBzIHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKFSJSTC9JFAvOSEQvF2u M4XTPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEm0PVkzLz5{M{C5OFk6OjxxYU6=
MCF7 M{XBfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1TBe|Q5KGi{cx?= M3XINWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhXEeLIE2gNE4yKM7:TT6= M1izd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEm0PVkzLz5{M{C5OFk6OjxxYU6=
HCT15 Ml2xS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVjBcnhmPDhiaILz M{DTUGdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGhEXDF3IHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKFSJSTC9JFAvOSEQvF2u M4LKU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEm0PVkzLz5{M{C5OFk6OjxxYU6=
IGROV1 MonPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mn;HOFghcHK| NFTOeYNIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBKT1KRVkGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiVFfJJF0hOC5zIN88UU4> MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzB7NEm5Nkc,OjNyOUS5PVI9N2F-
PC3 Mm\XS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUG0PEBpenN? NVPue29zT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hWEN|IHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKFSJSTC9JFAvOSEQvF2u MlTCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyOUS5PVIoRjJ|MEm0PVkzRC:jPh?=
HCT116 NHKx[|BIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MY[0PEBpenN? M4G5Xmdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGhEXDFzNjDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCWR1mgQUAxNjFizszNMi=> M4LTVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEm0PVkzLz5{M{C5OFk6OjxxYU6=
A549 MkX5R5l1d3SxeHnjbZR6KGG|c3H5 NVzSXW54S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gNU42PCEQvF2u MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF4NEexNEc,OjNzNkS3NVA9N2F-
BGC823 MVTDfZRwfG:6aXPpeJkh[XO|YYm= NGO0RYhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBDT0N6MkOgZ4VtdHNiYomgUXRVKG2ndHjv[EwhUUN3MDC9JFMvQDRizszNMi=> NVr2cXl1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxOlQ4OTBpPkKzNVY1PzFyPD;hQi=>
Bel7042 Ml3VR5l1d3SxeHnjbZR6KGG|c3H5 NEPEWmVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBD\Wx5MESyJINmdGy|IHL5JG1VXCCvZYToc4QtKEmFNUCgQUA{Njh3IN88UU4> NGq5b3A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G2OFcyOCd-MkOxOlQ4OTB:L3G+
HCT8 MnjDR5l1d3SxeHnjbZR6KGG|c3H5 M1LWXWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDhiY3XscJMh[nliTWTUJI1mfGixZDygTWM2OCB;IEWuN|gh|ryPLh?= MlG1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzNkS3NVAoRjJ|MU[0O|ExRC:jPh?=
A2780 NX3lUld1S3m2b4TvfIlkcXS7IHHzd4F6 MlPqR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVI4QDBiY3XscJMh[nliTWTUJI1mfGixZDygTWM2OCB;IEWuOEDPxE1w MlnIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzNkS3NVAoRjJ|MU[0O|ExRC:jPh?=
NIH-H460 MWXDfZRwfG:6aXPpeJkh[XO|YYm= M{ji[2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG5KUC2KNE[wJINmdGy|IHL5JG1VXCCvZYToc4QtKEmFNUCgQUA4NjF{IN88UU4> MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF4NEexNEc,OjNzNkS3NVA9N2F-
HepG2 NYTYeIZ3S3m2b4TvfIlkcXS7IHHzd4F6 NYnL[lk3OjRiaILz MlHwR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgNlQhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI6Njh5IN88UU4> MkS3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{MEK0PFQoRjJ|MkCyOFg1RC:jPh?=
PA1 MYrDfZRwfG:6aXPpeJkh[XO|YYm= NI[zXmwzPCCqcoO= NWrBSIw6S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWEFzIHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{QS53IN88UU4> NH\WbnU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{KwNlQ5PCd-MkOyNFI1QDR:L3G+
HCT15 MlvIR5l1d3SxeHnjbZR6KGG|c3H5 MnHiNlQhcHK| MVLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3QyPSClZXzsd{Bi\nSncjCyOEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOFUvODFizszNMi=> MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzJyMkS4OEc,OjN{MEK0PFQ9N2F-
MCF7 M33lTWN6fG:2b4jpZ4l1gSCjc4PhfS=> MXK3NkBpenN? M1XaZmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE4NjJizszNMi=> NIrIPZA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{K3PVg3PCd-MkOyO|k5PjR:L3G+
HepG2 M3LH[2N6fG:2b4jpZ4l1gSCjc4PhfS=> Mm\lO|IhcHK| NXfCeJRlS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJzLkmg{txONg>? NGDFcY09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{K3PVg3PCd-MkOyO|k5PjR:L3G+
SGC7901 Mn\VR5l1d3SxeHnjbZR6KGG|c3H5 MkT3O|IhcHK| NFnJUFdEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUT0N5OUCxJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{OD61JO69VS5? MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzJ5OUi2OEc,OjN{N{m4OlQ9N2F-
HCT116 M2LsfmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M{HmVFQ5KGi{cx?= MlzmRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiClZXzsJJBzd2yrZnXyZZRqd25iYX\0[ZIhPDhiaILzJIJ6KFO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGlEPTBiPTCzMlU3KM7:TT6= MoHDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN|MEW5NVkoRjJ|M{C1PVE6RC:jPh?=
B16F10 MYDBcpRq[2GwY3XyJIF{e2G7 NFKzVnQ1QCCqcoO= NGjYOmpCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhdW:3c3WgRlE3TjFyIHPlcIx{KGG|c3Xzd4VlKGG|IHPlcIwhe3W{dnn2ZYwhdWWjc4Xy[YQh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIyNjRzIN88UU4> NELsfJI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{OxNlk1QSd-MkOzNVI6PDl:L3G+
SGC7901 NFW1coZCdnSrY3HuZ4VzKGG|c3H5 MWG0PEBpenN? MljKRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPHR|c6ODFiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB{fXK4aY\hcEBu\WG|dYLl[EBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOFYvOzVizszNMi=> MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzNzMkm0PUc,OjN|MUK5OFk9N2F-
HeLa M1vHd2FvfGm2dX3vdkBie3OjeR?= NEmxUnM1QCCqcoO= M3XkTGFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZZN{\XO|ZXSgZZMh\3Kxd4ToJIlvcGmkaYTpc44hdWWjc4Xy[YQh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE1Njd6IN88UU4> MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzNzM{[zOUc,OjN|MUO2N|U9N2F-
A549 NGSyfllIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWm0PEBpenN? MVvHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC1MlY1KM7:TT6= MmDpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN|NUO3N|coRjJ|M{WzO|M4RC:jPh?=
QGY7701 M3TLc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFX3XW81QCCqcoO= MWnHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDRS3k4PzBzIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPC5|IN88UU4> MmfWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN|NUO3N|coRjJ|M{WzO|M4RC:jPh?=
HuH7 MoDaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NELSSXU1QCCqcoO= NX7CTo1[T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hUHWKNzDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTVwOEWg{txONg>? NVGybXVmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOzOVM4OzdpPkKzN|U{PzN5PD;hQi=>
HeLa NF\3V|dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M13xXVQ5KGi{cx?= MVrHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOk4{OiEQvF2u NI\Vco49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{O1N|c{Pyd-MkOzOVM4Ozd:L3G+
L02 MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGfvfZU1QCCqcoO= NHPUUYVIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBNODJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQ3NjV5IN88UU4> MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzN3M{ezO{c,OjN|NUO3N|c9N2F-
EC109 Mn3vR5l1d3SxeHnjbZR6KGG|c3H5 NFn0OWs4OiCqcoO= M3rJcmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGVEOTB7IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|LkO0JO69VS5? MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzN3M{e0N{c,OjN|NUO3OFM9N2F-
MGC803 M1nRSGN6fG:2b4jpZ4l1gSCjc4PhfS=> M4HnRVczKGi{cx?= NWPxNIhiS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUeFOECzJINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC3MlAyKM7:TT6= MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzN3M{e0N{c,OjN|NUO3OFM9N2F-
MCF7 NIPw[phEgXSxdH;4bYNqfHliYYPzZZk> M2fWS|czKGi{cx?= MorPR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPy53NDFOwG0v MofMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN|NUO3OFMoRjJ|M{WzO|Q{RC:jPh?=
PC3 MoDYR5l1d3SxeHnjbZR6KGG|c3H5 NI\mdmI4OiCqcoO= NH7aPIJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ5LkC3JO69VS5? MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzN3M{e0N{c,OjN|NUO3OFM9N2F-
colon cancer M1vKfmN6fG:2b4jpZ4l1gSCjc4PhfS=> NFLDZ281QCCqcoO= MWPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDjc4xwdiClYX7j[ZIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cJBpd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hQC52IN88UU4> MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzR5NEi5PUc,OjN2N{S4PVk9N2F-
leukemia Ml;tR5l1d3SxeHnjbZR6KGG|c3H5 NHq0U4Y1QCCqcoO= NXHoNZJLS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hdGW3a3XtbYEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cJBpd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOTVwMTFOwG0v MmPsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN2N{S4PVkoRjJ|NEe0PFk6RC:jPh?=
prostate cancer Mn:1R5l1d3SxeHnjbZR6KGG|c3H5 MlS2OFghcHK| MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDwdo9{fGG2ZTDjZY5k\XJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dHCqb4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMkKuO{DPxE1w Mn73QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN2N{S4PVkoRjJ|NEe0PFk6RC:jPh?=
renal cancer M2q1bWN6fG:2b4jpZ4l1gSCjc4PhfS=> NYruVo5xPDhiaILz MmPNR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gdoVv[WxiY3HuZ4VzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxxcG:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDR3Lk[g{txONg>? Ml7wQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN2N{S4PVkoRjJ|NEe0PFk6RC:jPh?=
MCF7 NF[yN5REgXSxdH;4bYNqfHliYYPzZZk> MX[0PEBpenN? NV3ncmEyS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTZwNzFOwG0v NGL5RZE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{S5NFE2QSd-MkO0PVAyPTl:L3G+
HepG2 Mm[5R5l1d3SxeHnjbZR6KGG|c3H5 NGC3eWU1QCCqcoO= NE\peHpEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOjJwODFOwG0v Mme3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN2OUCxOVkoRjJ|NEmwNVU6RC:jPh?=
SGC7901 M4\iWWN6fG:2b4jpZ4l1gSCjc4PhfS=> M17l[|Q5KGi{cx?= NX7Ld2NCS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0eFN{mwNUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMkiuPUDPxE1w MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzR7MEG1PUc,OjN2OUCxOVk9N2F-
THP1 NVvTNJpFSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NGLSPHA1QCCqcoO= M1HXNGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iVFjQNUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhUUN3MDC9JFEh|ryPLh?= NW\6XlV7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1NFEyOTNpPkKzOVAyOTF|PD;hQi=>
PC3 NUfSRZk{SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= Mk[zOFghcHK| Mnu5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCSQ{OgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGlEPTBiPTCyMlIh|ryPLh?= NFTCUGM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{WwNVEyOyd-MkO1NFEyOTN:L3G+
Hep2 NHLlZ2JCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M2SxTlQ5KGi{cx?= MWfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEincEKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGlEPTBiPTC0MlUh|ryPLh?= NF7nO5Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{WwNVEyOyd-MkO1NFEyOTN:L3G+
A549 M33xT2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NIrVcIE1QCCqcoO= NXmxSFhPSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCLQ{WwJF0hPC57IN88UU4> MoDkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN3MEGxNVMoRjJ|NUCxNVE{RC:jPh?=
K562 NX20d|NES3m2b4TvfIlkcXS7IHHzd4F6 NY\zenJ6PzJiaILz M1i1NmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGs2PjJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI5KM7:TT6= Mn3PQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN3M{WzNlIoRjJ|NUO1N|IzRC:jPh?=
CEM MVvDfZRwfG:6aXPpeJkh[XO|YYm= NFPjenY4OiCqcoO= MX;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOyJO69VS5? NWXHTIwxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1N|U{OjJpPkKzOVM2OzJ{PD;hQi=>
A375-S2 MV3DfZRwfG:6aXPpeJkh[XO|YYm= MlvUOFghcHK| NHnZeoNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCOzd3LWOyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB4Lk[3JO69VS5? NYTzO5VtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1OVgzOzhpPkKzOVU5OjN6PD;hQi=>
HeLa M1K0dWN6fG:2b4jpZ4l1gSCjc4PhfS=> NHSwO2c1QCCqcoO= M3q5cWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFcvOzRizszNMi=> NFfwdY89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{W1PFI{QCd-MkO1OVgzOzh:L3G+
HL60 NGXKdmxEgXSxdH;4bYNqfHliYYPzZZk> M1;EbFQ5KGi{cx?= NFLY[pdEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJVDZyIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOC5yNTFOwG0v MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzV3OEKzPEc,OjN3NUiyN|g9N2F-
MCF7 MmDqR5l1d3SxeHnjbZR6KGG|c3H5 Mn3GOFghcHK| NUH5ZWZvS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTFwNTFOwG0v NWLOcJBbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1OVgzOzhpPkKzOVU5OjN6PD;hQi=>
K562 NEXZdHNEgXSxdH;4bYNqfHliYYPzZZk> MVG0PEBpenN? MkGyR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT|U3OiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlMvPTVizszNMi=> MoXiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN3NUiyN|goRjJ|NUW4NlM5RC:jPh?=
U937 MYHDfZRwfG:6aXPpeJkh[XO|YYm= NUP5RpJCPDhiaILz MXzDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDVPVM4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyN{46OyEQvF2u NWSxdY92RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1OVgzOzhpPkKzOVU5OjN6PD;hQi=>
HCT116 MUDDfZRwfG:6aXPpeJkh[XO|YYm= MmTjOFghcHK| NWTqWIk1S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{Nz63OkDPxE1w M1jmRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NUW4NlM5Lz5{M{W1PFI{QDxxYU6=
HT1080 M{DkN2N6fG:2b4jpZ4l1gSCjc4PhfS=> NUXmU2YzPDhiaILz MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWFExQDBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFM2NjZ{IN88UU4> MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzV3OEKzPEc,OjN3NUiyN|g9N2F-
HepG2 MYDDfZRwfG:6aXPpeJkh[XO|YYm= NYHrOYNVPDhiaILz NVTlV|JwS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDRyLkO0JO69VS5? NGWxZ2U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{W1PFI{QCd-MkO1OVgzOzh:L3G+
A549 Ml;kR5l1d3SxeHnjbZR6KGG|c3H5 MnLkOFghcHK| NVnGd3JjS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPDRwMEWg{txONg>? M4G2bFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NUW4NlM5Lz5{M{W1PFI{QDxxYU6=
EC9706 MoXMR5l1d3SxeHnjbZR6KGG|c3H5 MWi3NkBpenN? M4DXVGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGVEQTdyNjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5|MjFOwG0v MnPZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4NESxPVMoRjJ|NkS0NVk{RC:jPh?=
MGC803 Ml3zR5l1d3SxeHnjbZR6KGG|c3H5 NIXxUW84OiCqcoO= NHzXUVhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOT0N6MEOgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDdwMUSg{txONg>? NGTLO4Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[0OFE6Oyd-MkO2OFQyQTN:L3G+
MCF7 MkfFR5l1d3SxeHnjbZR6KGG|c3H5 M3XacVczKGi{cx?= Mmq5R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gO{4{OyEQvF2u NIfIOnQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[0OFE6Oyd-MkO2OFQyQTN:L3G+
SMMC7721 NFvwS25EgXSxdH;4bYNqfHliYYPzZZk> NGewV4E4OiCqcoO= M3mzO2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNOVUN5N{KxJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{Nj63NUDPxE1w M3XjeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkS0NVk{Lz5{M{[0OFE6OzxxYU6=
HCT116 NH\VTJJEgXSxdH;4bYNqfHliYYPzZZk> NWjidHg2PDhiaILz NYfiTphUS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBKSzVyIE2gOE42OiEQvF2u NHnYZYs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[0OFIyPSd-MkO2OFQzOTV:L3G+
HT-29 NH7SOYxEgXSxdH;4bYNqfHliYYPzZZk> NX;zZZdkPDhiaILz M{DqUWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhVNTJ7IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDJR|UxKD1iNj6zOUDPxE1w NW\FSo5QRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2OFQzOTVpPkKzOlQ1OjF3PD;hQi=>
A549 NUGwTo16SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MnXSO|IhcHK| MnfuRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDNUS5JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|LkWyJO69VS5? M1;NN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Nk[1NVA3Lz5{M{[2OVExPjxxYU6=
HCT116 M{XHRWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NXPYcm5lPzJiaILz MoP0RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEWuOVMh|ryPLh?= M2WxWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Nk[1NVA3Lz5{M{[2OVExPjxxYU6=
HT-29 NIDsW4ZCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NULVfGIyPzJiaILz M3zWSWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSGStNlkh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEK0MlUh|ryPLh?= Mo\iQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4NkWxNFYoRjJ|Nk[1NVA3RC:jPh?=
MCF7 M{\0dWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NX\1bJlLPzJiaILz MoH3RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|Mj6xPEDPxE1w MonaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4NkWxNFYoRjJ|Nk[1NVA3RC:jPh?=
HeLa MmrRRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NIfydnE4OiCqcoO= NELjRnpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IESzMlcyKM7:TT6= NYHUUGxmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2OlUyODZpPkKzOlY2OTB4PD;hQi=>
colon cancer M1exdGN6fG:2b4jpZ4l1gSCjc4PhfS=> MYW0PEBpenN? MYXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDjc4xwdiClYX7j[ZIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IHPveYx1\XJiY3;1cpRmeiCjbnHsfZNqeyxiR1m1NEA:KDhwNDFOwG0v M13xbVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkizOVkzLz5{M{[4N|U6OjxxYU6=
leukemia MmnER5l1d3SxeHnjbZR6KGG|c3H5 NH6wN2k1QCCqcoO= M4j4dGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJIxmfWunbXnhJINmdGy|IHHmeIVzKDR6IHjyd{BjgSClb4XseIVzKGOxdX70[ZIh[W6jbInzbZMtKEeLNUCgQUAyPS5zIN88UU4> MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ6M{W5Nkc,OjN4OEO1PVI9N2F-
prostate cancer NWi1[JBpS3m2b4TvfIlkcXS7IHHzd4F6 MU[0PEBpenN? MljUR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gdJJwe3SjdHWgZ4Fv[2W{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBkd3WudHXyJINwfW62ZYKgZY5idHm|aYOsJGdKPTBiPTCyNk44KM7:TT6= NVjiZm5XRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2PFM2QTJpPkKzOlg{PTl{PD;hQi=>
renal cancer MoHvR5l1d3SxeHnjbZR6KGG|c3H5 MYK0PEBpenN? NYSzSmRsS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hemWwYXygZ4Fv[2W{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBkd3WudHXyJINwfW62ZYKgZY5idHm|aYOsJGdKPTBiPTC0OU43KM7:TT6= NYi0T2I3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2PFM2QTJpPkKzOlg{PTl{PD;hQi=>
SH-SY5Y MX7DfZRwfG:6aXPpeJkh[XO|YYm= M4DUZ|czKGi{cx?= NVnLTFNXS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0hvU2m1XUBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD65O{DPxE1w MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ6NUW3NUc,OjN4OEW1O|E9N2F-
HCT116 NX3Me|d7S3m2b4TvfIlkcXS7IHHzd4F6 MorOO|IhcHK| MVHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFMvOjRizszNMi=> M2\5fFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Nki1OVcyLz5{M{[4OVU4OTxxYU6=
A549 MYnDfZRwfG:6aXPpeJkh[XO|YYm= M33jVVczKGi{cx?= NH3GPGhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA5NjdzIN88UU4> NGHUOo49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[4OVU4OSd-MkO2PFU2PzF:L3G+
Vero MoTGR5l1d3SxeHnjbZR6KGG|c3H5 NWXFS25nPzJiaILz NVq2[2NFS3m2b4TvfIlkcXS7IHHnZYlve3RiQX\ybYNidiCpcnXlckBud26tZYmgWoVzdyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gPU44OSEQvF2u NYLrW3lHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2PFU2PzFpPkKzOlg2PTdzPD;hQi=>
MCF7 MlrIR5l1d3SxeHnjbZR6KGG|c3H5 NVjUVpNWPzJiaILz MljrR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVAvOTRizszNMi=> NVPIfVBRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2PFU2PzFpPkKzOlg2PTdzPD;hQi=>
HepG2 M3n0ZWN6fG:2b4jpZ4l1gSCjc4PhfS=> NFXjSoc4OiCqcoO= MYnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlQvQTZizszNMi=> NYXHNlhMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2PFU2PzFpPkKzOlg2PTdzPD;hQi=>
PC3 MYXBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MXi3NkBpenN? MnjkRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCSQ{OgZ4VtdHNiZYjwdoV{e2mwZzDTT3AzKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzPy5yNzFOwG0v NIX6XG89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{ezOVI5OSd-MkO3N|UzQDF:L3G+
PC3 NYmwe2pJSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NEK1Zpc4OiCqcoO= MkXPRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCSQ{OgZ4VtdHNiZYjwdoV{e2mwZzDQR2RPSSCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOzFwNESg{txONg>? MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzd|NUK4NUc,OjN5M{WyPFE9N2F-
COLO320DM NWfGeY97S3m2b4TvfIlkcXS7IHHzd4F6 MUK0PEBpenN? NWDu[oRFS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hS0:OT{OyNGROKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyJO69VS5? NV3pfWZSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO3PVI{PTJpPkKzO|kzOzV{PD;hQi=>
HeLa M4e0U2N6fG:2b4jpZ4l1gSCjc4PhfS=> NXHY[WF{PzJiaILz NFTvc25EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{NjRizszNMi=> M4PpTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|N{myO|Y{Lz5{M{e5Nlc3OzxxYU6=
MCF7 M4rxfGN6fG:2b4jpZ4l1gSCjc4PhfS=> MoruO|IhcHK| NWXZcZUxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOy54IN88UU4> M4\XeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|N{myO|Y{Lz5{M{e5Nlc3OzxxYU6=
SW480 MV7DfZRwfG:6aXPpeJkh[XO|YYm= M2G0fFczKGi{cx?= NWS4e4VxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW1d2OECgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDhwMTFOwG0v M4jWXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|N{myO|Y{Lz5{M{e5Nlc3OzxxYU6=
MDA-MB-435S M2LJZWN6fG:2b4jpZ4l1gSCjc4PhfS=> NF\k[mY4OiCqcoO= NGW3NY9EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOTEFvTVKtOFM2WyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVQvPSEQvF2u MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzd7Mke2N{c,OjN5OUK3OlM9N2F-
LM7 NGm5fItEgXSxdH;4bYNqfHliYYPzZZk> NVWyeoVqPzJiaILz NIG1cmFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBNVTdiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE5NjZizszNMi=> NEWye2w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{e5Nlc3Oyd-MkO3PVI4PjN:L3G+
MGC803 MnGwR5l1d3SxeHnjbZR6KGG|c3H5 M{HzcFczKGi{cx?= NGDWXpJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOT0N6MEOgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDZwOUKg{txONg>? NHzMOlQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{e5Nlc3PCd-MkO3PVI4PjR:L3G+
MCF7 NVvJb2ZsS3m2b4TvfIlkcXS7IHHzd4F6 MkSwO|IhcHK| MXXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC3MlU1KM7:TT6= NFLlVm09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{e5Nlc3PCd-MkO3PVI4PjR:L3G+
SMMC7721 NV64enROS3m2b4TvfIlkcXS7IHHzd4F6 MoPLO|IhcHK| MXzDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTUW1EPzd{MTDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hQS55ODFOwG0v NEPJbpk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{e5Nlc3PCd-MkO3PVI4PjR:L3G+
EC109 MWTDfZRwfG:6aXPpeJkh[XO|YYm= MnLvO|IhcHK| NF;kfFhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBGSzFyOTDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTBwNkGg{txONg>? NFfkeZc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{e5Nlc3PCd-MkO3PVI4PjR:L3G+
PC3 NFy2VFFEgXSxdH;4bYNqfHliYYPzZZk> NFr3bnU4OiCqcoO= MmTGR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyOE44PiEQvF2u NVvidZluRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO3PVI4PjRpPkKzO|kzPzZ2PD;hQi=>
MCF7 MmjCRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M2rqN|Q5KGi{cx?= MWHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDVizszNMi=> MmfXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6MECzPVEoRjJ|OECwN|kyRC:jPh?=
Vero NEH6WXFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M4TSW|Q5KGi{cx?= NUXCRYtVSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBi\nKrY3HuJIdz\WWwIH3vcotmgSCYZYLvJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB6IN88UU4> NVTqcW1DRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4NFA{QTFpPkKzPFAxOzlzPD;hQi=>
WI38 NETJO3pCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NHn6NHc1QCCqcoO= M1jyfWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iV1mzPEBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUCg{txONg>? M{HTPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OECwN|kyLz5{M{iwNFM6OTxxYU6=
HepG2 MlGxRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NUfH[YNxPDhiaILz MmHQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZYDHNkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUCg{txONg>? MkiwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6MECzPVEoRjJ|OECwN|kyRC:jPh?=
HL60 MWjDfZRwfG:6aXPpeJkh[XO|YYm= M2jkcFQ5KGi{cx?= NFHJSYNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJVDZyIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzOi5|IN88UU4> NV7qb|lrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4Olc{QDVpPkKzPFY4Ozh3PD;hQi=>
H460 MUTDfZRwfG:6aXPpeJkh[XO|YYm= MnnDOFghcHK| NY\DVZRNS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUDR4MDDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOjZwNzFOwG0v M3rkWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OE[3N|g2Lz5{M{i2O|M5PTxxYU6=
KB MnTwR5l1d3SxeHnjbZR6KGG|c3H5 MnXDO|IhcHK| M37Jc2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGtDKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTC0Mlg1KM7:TT6= MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh4N{[wN{c,OjN6Nke2NFM9N2F-
HeLa NHuyUpFEgXSxdH;4bYNqfHliYYPzZZk> NFzYUJg4OiCqcoO= M13KZWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFYvOjNizszNMi=> NFXzXnM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i2O|YxOyd-MkO4Olc3ODN:L3G+
MCF7 NXvIU4Z[S3m2b4TvfIlkcXS7IHHzd4F6 NFj3e404OiCqcoO= NVzTdZJ[S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA4OiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hPi53MzFOwG0v MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh4N{[wN{c,OjN6Nke2NFM9N2F-
OVCAR3 MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXrYSYJCPDhiaILz NFfO[5RIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBQXkODUkOgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCwMlAyKM7:TT6= M3rHWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
SR NV\Lc|NqT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M13aOVQ5KGi{cx?= NU\ae2hST3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hW1JiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkCyJO69VS5? M1nLT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
RPMI8226 MkfiS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYXDZWNIPDhiaILz NUPPb|A4T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPSUiyNlYh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAxNjB2IN88UU4> MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh6N{C1OUc,OjN6OEewOVU9N2F-
MALME-3M M4T3N2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnzKOFghcHK| Mn\IS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUWFNVUVvM12gZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCwMlA2KM7:TT6= NVzGOGhCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4PFcxPTVpPkKzPFg4ODV3PD;hQi=>
HCC2998 NUjRU5VbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYTG[GZKPDhiaILz NHf0NXVIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBJS0N{OUm4JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNE4xPSEQvF2u NFzTO4w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
NCI-H460 M{XR[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NF[yV2M1QCCqcoO= MXzHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDOR2kuUDR4MDDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuNFUh|ryPLh?= Mm\CQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6OEewOVUoRjJ|OEi3NFU2RC:jPh?=
SF539 MojqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mn3FOFghcHK| MmHCS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gV2Y2OzliY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkC2JO69VS5? NFPGNWM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
MCF7 MmrHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3\jfVQ5KGi{cx?= MlfzS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDBwMEeg{txONg>? NWjyNYdJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4PFcxPTVpPkKzPFg4ODV3PD;hQi=>
CAKI-1 Ml7WS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlvMOFghcHK| M1Lse2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGNCU0lvMTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuNFch|ryPLh?= MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh6N{C1OUc,OjN6OEewOVU9N2F-
MDA-MB-435 NXrmXGNLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYq0PEBpenN? NUfQRo1KT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hVUSDLV3CMVQ{PSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDBwMEeg{txONg>? M1PUZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
HCT15 NFTYdIpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NH6wXG41QCCqcoO= NIDVOnpIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBJS1RzNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuNVEh|ryPLh?= M3;KU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
COLO205 NWf0cng1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF76ZZc1QCCqcoO= NHzVWGZIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBEV0yRMkC1JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNE4yPSEQvF2u MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh6N{C1OUc,OjN6OEewOVU9N2F-
HT-29 NIjGdYxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWnTcYZ1PDhiaILz MnvhS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTHQuOjliY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSByLkG3JO69VS5? NX3UUmhvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4PFcxPTVpPkKzPFg4ODV3PD;hQi=>
A549/ATCC NWWxcmtyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYi0PEBpenN? M2j2UGdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGE2PDlxQWTDR{Bk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFAvOThizszNMi=> MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh6N{C1OUc,OjN6OEewOVU9N2F-
KM12 MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIS5fJg1QCCqcoO= NVjNV4N1T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hU01zMjDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuNlEh|ryPLh?= NFrCOWk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
HCT116 NXHze3V2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHzQOo81QCCqcoO= NXPrenJGT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hUEOWMUG2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNE4zOiEQvF2u M{P6eFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
SF295 M1rKTWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NE\aZYo1QCCqcoO= M4\6fGdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJHNHOjl3IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6yNkDPxE1w MnPkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6OEewOVUoRjJ|OEi3NFU2RC:jPh?=
LOXIMVI M2HSZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFnRc241QCCqcoO= NH;CeYpIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBNV1iLTW\JJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNE4zPCEQvF2u Mni5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6OEewOVUoRjJ|OEi3NFU2RC:jPh?=
ACHN MkniS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXWyd5hCPDhiaILz MXTHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDBR2hPKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOC5{OTFOwG0v M1XNWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
NCI-ADR-RES NUO3XJNET3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWm0dFJ4PDhiaILz M3XiTWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2DRGKtVmVUKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOC5|MTFOwG0v MoPRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6OEewOVUoRjJ|OEi3NFU2RC:jPh?=
NCI-H23 MljPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYLDVpp3PDhiaILz NELkVJZIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKzJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNE4{OyEQvF2u NWO1TGZMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4PFcxPTVpPkKzPFg4ODV3PD;hQi=>
A498 NV\TcnVpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3XVZlQ5KGi{cx?= MYTHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDBOFk5KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOC5|NTFOwG0v M4PW[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
MOLT4 NXjjdVdrT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGH3cFk1QCCqcoO= M{PzeWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG1QVFR2IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD6zOUDPxE1w NHPtRnc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
DU145 M3fuemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVe0PEBpenN? NWrKToxbT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hTFVzNEWgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCwMlM3KM7:TT6= NVr5SFVVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4PFcxPTVpPkKzPFg4ODV3PD;hQi=>
HOP62 NWT2XYlIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmfQOFghcHK| MWXHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDIU3A3OiClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NEA:KDBwM{mg{txONg>? M3zRUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
SK-MEL-5 MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYW0PEBpenN? NYDCfo0{T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTVXMMVUh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAxNjR4IN88UU4> NW\BTmJPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4PFcxPTVpPkKzPFg4ODV3PD;hQi=>
SN12C NHH2WIhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV20PEBpenN? NFfrWnNIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBUVjF{QzDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuOFkh|ryPLh?= MmLHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6OEewOVUoRjJ|OEi3NFU2RC:jPh?=
UACC62 NEe2VGRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mle4OFghcHK| NH32S3JIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBWSUOFNkKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCwMlUzKM7:TT6= NXPQTWdVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4PFcxPTVpPkKzPFg4ODV3PD;hQi=>
786-0 NWrFOm44T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGTnfY81QCCqcoO= M{LJOWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJFc5Pi1yIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD63NkDPxE1w NGHIb|M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
U251 MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFrOSFg1QCCqcoO= NUXzc481T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hXTJ3MTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IECuPUDPxE1w NELETIM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
SW620 NWXtSVl4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4XkdlQ5KGi{cx?= M3Sxdmdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJHNYPjJyIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iMD65NkDPxE1w MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh6N{C1OUc,OjN6OEewOVU9N2F-
M14 NYjEToNkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NU[wTZRvPDhiaILz Mm\hS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUVE1KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOC57ODFOwG0v NVn1cIdyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4PFcxPTVpPkKzPFg4ODV3PD;hQi=>
SK-MEL-28 NIDOXYZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUjwbWVGPDhiaILz NGC3ZmZIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBUUy2PRVytNlgh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAyNjB|IN88UU4> MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh6N{C1OUc,OjN6OEewOVU9N2F-
TK10 NX:5coxjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3;zbVQ5KGi{cx?= NVrNRXZ2T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hXEtzMDDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEGuNVIh|ryPLh?= NGO0Wos9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
IGROV1 NETqUYZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXTCRppNPDhiaILz NYLj[olnT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hUUeUT2[xJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNU4zOiEQvF2u M2m2OVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
UO31 MnnDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MX20PEBpenN? MYfHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDVU|MyKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOS52MjFOwG0v M{HZb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
SF268 M1;Rc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3fWTVQ5KGi{cx?= MmTVS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gV2YzPjhiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSBzLk[yJO69VS5? NH3BdmE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
OVCAR8 MlXSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIXFeFU1QCCqcoO= MUHHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDPWmNCWjhiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSBzLke0JO69VS5? MoD1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6OEewOVUoRjJ|OEi3NFU2RC:jPh?=
HL-60(TB) NUO0[|NXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYfKXmRNPDhiaILz MlvJS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTGwuPjBqVFKpJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNk4{KM7:TT6= NUPHNI5jRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4PFcxPTVpPkKzPFg4ODV3PD;hQi=>
PC3 M37R[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWXpUVVKPDhiaILz MULHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDQR|Mh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAzNjN4IN88UU4> NIn0R2k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
RXF393 MkTvS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFTHdIE1QCCqcoO= NHT3eW5Iem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBTYEZ|OUOgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCyMlYyKM7:TT6= M4\WW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
UACC257 M3\MbGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGLuWnA1QCCqcoO= MlrKS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gWWFESzJ3NzDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEOuOVUh|ryPLh?= NXjWNpJHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4PFcxPTVpPkKzPFg4ODV3PD;hQi=>
K562 MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHi3VGk1QCCqcoO= MUjHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOy53ODFOwG0v MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh6N{C1OUc,OjN6OEewOVU9N2F-
SNB19 MoXDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVLtcos5PDhiaILz NYH5OYZiT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hW06EMUmgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCzMlgyKM7:TT6= NF\6OnA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
OVCAR4 NIn2cVVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlO4OFghcHK| MlHpS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gU3ZESVJ2IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iND60N{DPxE1w Mln6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6OEewOVUoRjJ|OEi3NFU2RC:jPh?=
MDA-MB-231 M2fQUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXzHSlU{PDhiaILz Mmf4S5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFYvPiEQvF2u NETqcVA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
NCI-H522 MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFfMT2U1QCCqcoO= MnjmS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUmNKNUh3MkKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTC3MlI4KM7:TT6= NGP1NpE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
T47D Moq1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NX\pe4E2PDhiaILz M{ToU2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJHQ1P0RiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB6LkGyJO69VS5? MoLUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6OEewOVUoRjJ|OEi3NFU2RC:jPh?=
Hs 578T MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4rWb|Q5KGi{cx?= MU\Hdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDId{A2PziWIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxKD1iOT63O{DPxE1w MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh6N{C1OUc,OjN6OEewOVU9N2F-
CCRF-CEM MoXwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnrCOFghcHK| NFX6RnhIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBES1KILVPFUUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFkvPzlizszNMi=> NGLHZXk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
BT549 MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NILtWWY1QCCqcoO= NVnMRXpwT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hSlR3NEmgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCxNE43KM7:TT6= NIT1T|Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i4O|A2PSd-MkO4PFcxPTV:L3G+
OVCAR5 MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mnr6OFghcHK| NV\KcVVGT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hV1[FQWK1JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyIE2gNVAvQSEQvF2u NXnHO29LRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4PFcxPTVpPkKzPFg4ODV3PD;hQi=>
SKOV3 MoX5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml3POFghcHK| MkjXS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gV2tQXjNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB{MT64JO69VS5? M1zUZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEi3NFU2Lz5{M{i4O|A2PTxxYU6=
A549 MmjaR5l1d3SxeHnjbZR6KGG|c3H5 NGL1coM1QCCqcoO= NEXLNnlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA2NjZ{IN88UU4> NFfyZ5M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{myNFI1Pid-MkO5NlAzPDZ:L3G+
SGC7901 MnjRR5l1d3SxeHnjbZR6KGG|c3H5 MonVOFghcHK| NYOyd3VMS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0eFN{mwNUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNj6wOEDPxE1w MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl{MEK0Okc,OjN7MkCyOFY9N2F-
MDA-MB-231 NUnjboZES3m2b4TvfIlkcXS7IHHzd4F6 MYe0PEBpenN? M4OweWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj2yN|Eh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGzMlY2KM7:TT6= MoTuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7MkCyOFYoRjJ|OUKwNlQ3RC:jPh?=
QGY7701 NWnpdGFbS3m2b4TvfIlkcXS7IHHzd4F6 NUTVc3AyPDhiaILz NVPtZnJRS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWUe\N{ewNUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUSuN{DPxE1w MlLzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7MkCyOFYoRjJ|OUKwNlQ3RC:jPh?=
SW480 NUXqS|FNS3m2b4TvfIlkcXS7IHHzd4F6 NHzoXZc1QCCqcoO= MYjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTW|Q5OCClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUvPzFizszNMi=> M2\iS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUKwNlQ3Lz5{M{myNFI1PjxxYU6=
HeLa NF7i[JREgXSxdH;4bYNqfHliYYPzZZk> NWDhT2doPDhiaILz M4OxVmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE3NjV{IN88UU4> MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl{MEK0Okc,OjN7MkCyOFY9N2F-
A549 MknmR5l1d3SxeHnjbZR6KGG|c3H5 M1XESFczKGi{cx?= MmTMR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG|c3H5MEBIUTVyIE2gN{43KM7:TT6= NFzYbIc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m2OFY4Pyd-MkO5OlQ3Pzd:L3G+
SKOV3 NHS4UlBEgXSxdH;4bYNqfHliYYPzZZk> M4PXblQ5KGi{cx?= MX3DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTT29XOyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlQvPDNizszNMi=> MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl6OEO1O{c,OjN7OEizOVc9N2F-
HepG2 Mkm1R5l1d3SxeHnjbZR6KGG|c3H5 M3rzSVQ5KGi{cx?= NGC0dlREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOjlwOUig{txONg>? M{jPNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUi4N|U4Lz5{M{m4PFM2PzxxYU6=
A549 MWLDfZRwfG:6aXPpeJkh[XO|YYm= MXS0PEBpenN? NWnvSopRS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOzRwM{Og{txONg>? MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl6OEO1O{c,OjN7OEizOVc9N2F-
NCI-H460 Ml\TR5l1d3SxeHnjbZR6KGG|c3H5 NIHZTGM1QCCqcoO= MXnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDOR2kuUDR4MDDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPDRwMESg{txONg>? MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl6OEO1O{c,OjN7OEizOVc9N2F-
leukemia NYWxOpJTS3m2b4TvfIlkcXS7IHHzd4F6 Ml;GOFghcHK| MXHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDs[ZVs\W2rYTDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hOS53MTFOwG0v NXmzelE4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO5PVQ{OjhpPkKzPVk1OzJ6PD;hQi=>
colon cancer MXvDfZRwfG:6aXPpeJkh[XO|YYm= NGfpVVE1QCCqcoO= NFLLN4VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBkd2yxbjDjZY5k\XJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFgvPCEQvF2u NYm0cJNERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO5PVQ{OjhpPkKzPVk1OzJ6PD;hQi=>
prostate cancer NW\j[5ZJS3m2b4TvfIlkcXS7IHHzd4F6 MnPOOFghcHK| NIPPWmVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBxem:|dHH0[UBk[W6lZYKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiR1m1NEA:KDJ{Lkeg{txONg>? MnjmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7OUSzNlgoRjJ|OUm0N|I5RC:jPh?=
renal cancer NGnuZplEgXSxdH;4bYNqfHliYYPzZZk> M1nCfVQ5KGi{cx?= NFrkc3NEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBz\W6jbDDjZY5k\XJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFQ2NjZizszNMi=> M{nDcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUm0N|I5Lz5{M{m5OFMzQDxxYU6=
A375-S2 NYXFUWhkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF7YNmk1QCCqcoO= MoKzS5Jwf3SqIHnubIljcXSrb36gZYdicW6|dDDoeY1idiCDM{e1MXMzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC2MlY4KM7:TT6= MomyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7OUmwOFYoRjJ|OUm5NFQ3RC:jPh?=
HeLa MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1KxNVQ5KGi{cx?= M3PNW2dzd3e2aDDpcohq[mm2aX;uJIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNz6zOEDPxE1w NV\0NYM{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO5PVkxPDZpPkKzPVk6ODR4PD;hQi=>
HL60 NXqzR45PT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYPySFhIPDhiaILz Ml7kS5Jwf3SqIHnubIljcXSrb36gZYdicW6|dDDoeY1idiCKTE[wJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMD6wOUDPxE1w M{PyWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUm5NFQ3Lz5{M{m5PVA1PjxxYU6=
MCF7 MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2rLN|Q5KGi{cx?= MVvHdo94fGhiaX7obYJqfGmxbjDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFzLkWg{txONg>? MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl7OUC0Okc,OjN7OUmwOFY9N2F-
K562 MlHSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmXuOFghcHK| MVrHdo94fGhiaX7obYJqfGmxbjDh[4FqdnO2IHj1cYFvKEt3NkKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ|LkW1JO69VS5? M1n3Z|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUm5NFQ3Lz5{M{m5PVA1PjxxYU6=
U937 NUi3eGVLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUi0PEBpenN? M4C3TGdzd3e2aDDpcohq[mm2aX;uJIFo[Wmwc4SgbJVu[W5iVUmzO{Bk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMkOuPVMh|ryPLh?= NVHTO29VRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO5PVkxPDZpPkKzPVk6ODR4PD;hQi=>
HCT116 Ml7QS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MonSOFghcHK| NUPUTlVWT3Kxd4ToJIlvcGmkaYTpc44h[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI4Njd4IN88UU4> MnPCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7OUmwOFYoRjJ|OUm5NFQ3RC:jPh?=
HT1080 NX3FbFNvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmW1OFghcHK| MVXHdo94fGhiaX7obYJqfGmxbjDh[4FqdnO2IHj1cYFvKEiWMUC4NEBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iM{WuOlIh|ryPLh?= NHHDR3A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m5PVA1Pid-MkO5PVkxPDZ:L3G+
HepG2 NULEdJpjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYK0PEBpenN? Mn;wS5Jwf3SqIHnubIljcXSrb36gZYdicW6|dDDoeY1idiCKZYDHNkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNECuN|Qh|ryPLh?= NIDtcZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m5PVA1Pid-MkO5PVkxPDZ:L3G+
A549 NGS1eIlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmPSOFghcHK| M4LuSmdzd3e2aDDpcohq[mm2aX;uJIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNESuNFUh|ryPLh?= MknoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7OUmwOFYoRjJ|OUm5NFQ3RC:jPh?=
QSG7701 MVfDfZRwfG:6aXPpeJkh[XO|YYm= NUfFZpNqPDhiaILz NGH2[2dEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBSW0d5N{CxJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCFQ1utPEBie3OjeTygTWM2OCB;IECuOkDPxE1w NYrvUZg3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwNVM1OTVpPkK0NFE{PDF3PD;hQi=>
HepG2 NFjodoJEgXSxdH;4bYNqfHliYYPzZZk> NXrndGJzPDhiaILz MX\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC0PEBpenNiYomgR2NMNThiYYPzZZktKEmFNUCgQUAyOi52ODFOwG0v NYnPdIpIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwNVM1OTVpPkK0NFE{PDF3PD;hQi=>
SMMC7721 M1LBemN6fG:2b4jpZ4l1gSCjc4PhfS=> NG\jNYQ1QCCqcoO= MWHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTUW1EPzd{MTDj[YxteyCjZoTldkA1QCCqcoOgZpkhS0ONLUigZZN{[XluIFnDOVAhRSBzND61OUDPxE1w NUHwdHNERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwNVM1OTVpPkK0NFE{PDF3PD;hQi=>
QGY7703 NIrkXFBEgXSxdH;4bYNqfHliYYPzZZk> M1K1[|Q5KGi{cx?= MWrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDRS3k4PzB|IHPlcIx{KGGodHXyJFQ5KGi{czDifUBES0tvODDhd5NigSxiSVO1NEA:KDF3Lk[2JO69VS5? NHTVWJA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NECxN|QyPSd-MkSwNVM1OTV:L3G+
Hep Mk\zR5l1d3SxeHnjbZR6KGG|c3H5 NWjJO4VSPDhiaILz NFKxcpZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvPSEQvF2u M17BeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEW2NVQ3Lz5{NEC1OlE1PjxxYU6=
IMR32 NVjsTY17S3m2b4TvfIlkcXS7IHHzd4F6 NGrUXWk1QCCqcoO= MVTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDJUXI{OiClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gNU4{KM7:TT6= NG\oXoE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEC1OlE1Pid-MkSwOVYyPDZ:L3G+
A549 NE\tToVEgXSxdH;4bYNqfHliYYPzZZk> M3L3cFI1KGi{cx?= MoLkR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjCyOEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNU4yKM7:TT6= Mk[1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyNkC0PFYoRjJ2ME[wOFg3RC:jPh?=
HeLa NUj3cW1oS3m2b4TvfIlkcXS7IHHzd4F6 NH7mdFczPCCqcoO= M3vhOmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgNlQhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEvOSEQvF2u NYDUflRKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwOlA1QDZpPkK0NFYxPDh4PD;hQi=>
MCF7 MYTDfZRwfG:6aXPpeJkh[XO|YYm= M{HmdVI1KGi{cx?= NX3OXm1MS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkAzPCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOS5{IN88UU4> NYTTSHFxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwOlA1QDZpPkK0NFYxPDh4PD;hQi=>
DU145 M1TrO2N6fG:2b4jpZ4l1gSCjc4PhfS=> MV[yOEBpenN? Mo\3R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSHUyPDViY3XscJMh[W[2ZYKgNlQhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEvOyEQvF2u NVfP[YQxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwOlA1QDZpPkK0NFYxPDh4PD;hQi=>
MGC803 M2DEXWN6fG:2b4jpZ4l1gSCjc4PhfS=> MXi3NkBpenN? M3XFPWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ISzhyMzDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNj65NkDPxE1w NE\zbpY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEC3O|E5Oid-MkSwO|cyQDJ:L3G+
MCF7 MlrBR5l1d3SxeHnjbZR6KGG|c3H5 MkLmO|IhcHK| M2G0NWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDdwNUSg{txONg>? NUjafWtRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwO|cyQDJpPkK0NFc4OTh{PD;hQi=>
SMMC7721 NH3s[WJEgXSxdH;4bYNqfHliYYPzZZk> NEm4V244OiCqcoO= NHj1fIZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUVU2FN{eyNUBk\WyuczDhd5Nme3OnZDDhd{Boem:5dHigbY5pcWKrdHnvckBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gPU44QCEQvF2u M2jTPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEe3NVgzLz5{NEC3O|E5OjxxYU6=
EC109 NXvrbnZiS3m2b4TvfIlkcXS7IHHzd4F6 M3mweVczKGi{cx?= M1TvW2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGVEOTB7IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMD62NUDPxE1w M{X1UlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEe3NVgzLz5{NEC3O|E5OjxxYU6=
PC3 NWq3SGwzS3m2b4TvfIlkcXS7IHHzd4F6 M1zSUlczKGi{cx?= NFLlNYREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ2Lke2JO69VS5? MojhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyN{exPFIoRjJ2MEe3NVgzRC:jPh?=
HCT8 NWrQc|lsSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MUnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiFVEigZ4VtdHNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOk46OiEQvF2u NHGwOJk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEC5OVA6PCd-MkSwPVUxQTR:L3G+
Bel7402 M{HTfWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MnzoRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCEZXy3OFAzKGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDhwMzFOwG0v M370TlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEm1NFk1Lz5{NEC5OVA6PDxxYU6=
A549 NIra[GdCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NWDKSYJlSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDhwOUKg{txONg>? MnfZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyOUWwPVQoRjJ2MEm1NFk1RC:jPh?=
SKOV3 M4P4W2N6fG:2b4jpZ4l1gSCjc4PhfS=> MmfUN{Bl[Xm| M1PPfmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNMV1Z|IHPlcIx{KGGodHXyJFMh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUAzPC52MzFOwG0v NUTReHNiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwPVU4PDVpPkK0NFk2PzR3PD;hQi=>
HepG2 NXzzU|NRS3m2b4TvfIlkcXS7IHHzd4F6 NV7ucIx1OyCmYYnz MX7DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjCzJIRigXNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlkvQThizszNMi=> MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDB7NUe0OUc,OjRyOUW3OFU9N2F-
A549 M2fMSGN6fG:2b4jpZ4l1gSCjc4PhfS=> M{\qe|Mh\GG7cx?= M{DtWWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgN{Bl[Xm|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFM1NjN|IN88UU4> MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDB7NUe0OUc,OjRyOUW3OFU9N2F-
NCI-H460 MUDDfZRwfG:6aXPpeJkh[XO|YYm= MYWzJIRigXN? MnG0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUmNKNUh2NkCgZ4VtdHNiYX\0[ZIhOyCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR2LkC0JO69VS5? MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDB7NUe0OUc,OjRyOUW3OFU9N2F-
MGC803 MljtR5l1d3SxeHnjbZR6KGG|c3H5 M4TxdVQ5KGi{cx?= NIrndGtEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOT0N6MEOgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDNwNkig{txONg>? NWHVSIN1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSxNVk5PjlpPkK0NVE6QDZ7PD;hQi=>
HepG2 NEPIUFdEgXSxdH;4bYNqfHliYYPzZZk> M{HxS|Q5KGi{cx?= MoPBR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQvOzVizszNMi=> Mn3BQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRzMUm4OlkoRjJ2MUG5PFY6RC:jPh?=
Bcap37 NYnoeppES3m2b4TvfIlkcXS7IHHzd4F6 M4fwPVQ5KGi{cx?= Mn3nR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRoNieDN5IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA2NjV6IN88UU4> MmfEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRzMUm4OlkoRjJ2MUG5PFY6RC:jPh?=
SGC7901 MlTVR5l1d3SxeHnjbZR6KGG|c3H5 NHfMdG01QCCqcoO= M2f2RWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNISzd7MEGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDdwM{eg{txONg>? MnrJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRzMUm4OlkoRjJ2MUG5PFY6RC:jPh?=
DU145 MVLDfZRwfG:6aXPpeJkh[XO|YYm= M4TnUGN6fG:2b4jpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFTVNVQ2KGOnbHzzMEBKSzVyIE2gN{41KM7:TT6= MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDF7NUS2Okc,OjRzOUW0OlY9N2F-
NCI-H460 MmHDR5l1d3SxeHnjbZR6KGG|c3H5 MUnDfZRwfG:6aXOgZYN1cX[rdImgZYdicW6|dDDoeY1idiCQQ1mtTFQ3OCClZXzsd{whUUN3MDC9JFgvPSEQvF2u NGPlPGw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEG5OVQ3Pid-MkSxPVU1PjZ:L3G+
HCT116 NFW3OVBEgXSxdH;4bYNqfHliYYPzZZk> MVm3NkBpenN? MXLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFgvOzJizszNMi=> MlXZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR{MUGwNlEoRjJ2MkGxNFIyRC:jPh?=
MGC803 NFvuc3dEgXSxdH;4bYNqfHliYYPzZZk> NFvNbVA4OiCqcoO= Mkf2R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWdEQDB|IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPS5|MjFOwG0v MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDJzMUCyNUc,OjR{MUGwNlE9N2F-
HepG2 MmWxR5l1d3SxeHnjbZR6KGG|c3H5 MlPSO|IhcHK| M4jMRWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyQS52NTFOwG0v NEPRbnU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEKxNVAzOSd-MkSyNVExOjF:L3G+
A549 NYDMV|RKS3m2b4TvfIlkcXS7IHHzd4F6 NVX4fYM2PzJiaILz M3fDVWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIxNjF|IN88UU4> NYrEOIk5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSyNVExOjFpPkK0NlEyODJzPD;hQi=>
NCI-H460 MoHtR5l1d3SxeHnjbZR6KGG|c3H5 NHPUdVc4OiCqcoO= NWTMb5pKS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVkOLLVi0OlAh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKzMlMzKM7:TT6= MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDJzMUCyNUc,OjR{MUGwNlE9N2F-
SW1116 M4jkSmN6fG:2b4jpZ4l1gSCjc4PhfS=> NHP4[m81QCCqcoO= NGDGXplEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUXzFzMU[gZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDVwMk[g{txONg>? MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDJ6Nke2NUc,OjR{OE[3OlE9N2F-
HepG2 MU\DfZRwfG:6aXPpeJkh[XO|YYm= NGXl[Wo1QCCqcoO= NIPURY1EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPy52MzFOwG0v NIjUO409[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEK4Olc3OSd-MkSyPFY4PjF:L3G+
BGC823 MUXDfZRwfG:6aXPpeJkh[XO|YYm= NEDnU5A1QCCqcoO= NXfhSnB[S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSkeFOEKzJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB5LkS4JO69VS5? MmLxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR{OE[3OlEoRjJ2Mki2O|YyRC:jPh?=
MCF7 NGezZ4xEgXSxdH;4bYNqfHliYYPzZZk> MVu0PEBpenN? M1:5VGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFkvPzlizszNMi=> NFjNR5I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEK4Olc3OSd-MkSyPFY4PjF:L3G+
MCF7 MYrDfZRwfG:6aXPpeJkh[XO|YYm= MXS0PEBpenN? MVTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlUh|ryPLh?= MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN|MkS5O{c,OjR|M{K0PVc9N2F-
B16 NWO5colFS3m2b4TvfIlkcXS7IHHzd4F6 MnHHOFghcHK| NETId3lEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBDOTZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQvOiEQvF2u NHLZ[HY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEOzNlQ6Pyd-MkSzN|I1QTd:L3G+
ME180 NX6wRZhPS3m2b4TvfIlkcXS7IHHzd4F6 M2\aeVQ5KGi{cx?= NULV[45iS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUVzOECgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDRwOTFOwG0v M{nSdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{OyOFk4Lz5{NEOzNlQ6PzxxYU6=
A549 M2\3[GN6fG:2b4jpZ4l1gSCjc4PhfS=> NHLpPIQ1KGSjeYO= MWfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IESg[IF6eyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlEh|ryPLh?= M161dVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{W5N|A{Lz5{NEO1PVMxOzxxYU6=
Bel7402 NWnmVVN{S3m2b4TvfIlkcXS7IHHzd4F6 MlH6OEBl[Xm| M3;aUmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGJmdDd2MEKgZ4VtdHNiYX\0[ZIhPCCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDVwNTFOwG0v M3PIWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{W5N|A{Lz5{NEO1PVMxOzxxYU6=
KB MlH2R5l1d3SxeHnjbZR6KGG|c3H5 MXW0JIRigXN? M3rlTGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGtDKGOnbHzzJIFnfGW{IESg[IF6eyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC4MlEh|ryPLh?= M2H3elxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{W5N|A{Lz5{NEO1PVMxOzxxYU6=
HCT116 Mn7MR5l1d3SxeHnjbZR6KGG|c3H5 M{fIPVQ5KGi{cx?= NHvUZ4dEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzMU[gZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDVwN{ig{txONg>? NIS0Xng9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEO3PFIyPyd-MkSzO|gzOTd:L3G+
HepG2 NXr4ZY12S3m2b4TvfIlkcXS7IHHzd4F6 MYS0PEBpenN? M3TOVGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzQS57ODFOwG0v M4HGc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{e4NlE4Lz5{NEO3PFIyPzxxYU6=
HeLa M1npOmN6fG:2b4jpZ4l1gSCjc4PhfS=> M3e1V|Q5KGi{cx?= NXmwUFE1S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOzVwM{Sg{txONg>? NWjIOpRrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSzO|gzOTdpPkK0N|c5OjF5PD;hQi=>
CNE MWfDfZRwfG:6aXPpeJkh[XO|YYm= M1vRUVQ5KGi{cx?= M4\uemN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNPTSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOFAvOjFizszNMi=> M1jEOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{e4NlE4Lz5{NEO3PFIyPzxxYU6=
SPCA2 NVLaO4lFS3m2b4TvfIlkcXS7IHHzd4F6 NE\GeWc1QCCqcoO= M{K4bWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNRS0F{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1Oi5{IN88UU4> M3;v[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{e4NlE4Lz5{NEO3PFIyPzxxYU6=
colon cancer NIjk[|ZEgXSxdH;4bYNqfHliYYPzZZk> MX2xNEB2VQ>? MXi0PEBpenN? NYfBRlh4S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4h[2:ub36gZ4Fv[2W{IHPlcIx{KGG2IEGwJJVOKGGodHXyJFQ5KGi{czygS2k2OCB;IEiuOEDPxE1w MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDR4OUGxNkc,OjR2NkmxNVI9N2F-
leukemia NXrKRo01S3m2b4TvfIlkcXS7IHHzd4F6 NEXSV4syOCC3TR?= MX20PEBpenN? NEe3[2xEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBt\XWtZX3pZUBk\WyuczDheEAyOCC3TTDh[pRmeiB2ODDodpMtKEeLNUCgQUAyPS5zIN88UU4> NF21bXI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NES2PVEyOid-MkS0OlkyOTJ:L3G+
prostate cancer NGWyd|hEgXSxdH;4bYNqfHliYYPzZZk> MlTSNVAhfU1? NIfCOos1QCCqcoO= MmTXR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gdJJwe3SjdHWgZ4Fv[2W{IHPlcIx{KGG2IEGwJJVOKGGodHXyJFQ5KGi{czygS2k2OCB;IEKyMlch|ryPLh?= NGHKXYY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NES2PVEyOid-MkS0OlkyOTJ:L3G+
renal cancer MUPDfZRwfG:6aXPpeJkh[XO|YYm= NGDqZpgyOCC3TR?= MYi0PEBpenN? MVPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDy[Y5idCClYX7j[ZIh[2WubIOgZZQhOTBidV2gZYZ1\XJiNEigbJJ{NCCJSUWwJF0hPDVwNjFOwG0v MnXCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR2NkmxNVIoRjJ2NE[5NVEzRC:jPh?=
EAC NF;6[25EgXSxdH;4bYNqfHliYYPzZZk> NH;OXmw1QCCqcoO= M1PyUGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KG2xdYPlJGVCSyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVQvOyEQvF2u NIfJSGw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEWzOFU{Pyd-MkS1N|Q2Ozd:L3G+
DLA NHK1bmREgXSxdH;4bYNqfHliYYPzZZk> NYjW[pJVPDhiaILz MVPDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W|ZTDEUGEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IITyfZBidiCkbIXlJIV5[2y3c3nvckBie3OjeTygTWM2OCB;IEG0MlMh|ryPLh?= NYHweZVQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS1N|Q2OzdpPkK0OVM1PTN5PD;hQi=>
DLA NYD3RpM{S3m2b4TvfIlkcXS7IHHzd4F6 Mm\JOFghcHK| MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBud3W|ZTDEUGEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG1Mlch|ryPLh?= MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDV|NEWzO{c,OjR3M{S1N|c9N2F-
DLA NGfPR|JEgXSxdH;4bYNqfHliYYPzZZk> MXG0PEBpenN? NX7Y[JB3S3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhTEyDIHPlcIx{KGGodHXyJFQ5KGi{czDifUBNTEhicnXs[YF{\SCjc4PhfUwhUUN3MDC9JFE2NjhizszNMi=> M2HPbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUO0OVM4Lz5{NEWzOFU{PzxxYU6=
EAC M{Ltc2N6fG:2b4jpZ4l1gSCjc4PhfS=> Ml;GOFghcHK| Mn7tR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgSWFEKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDMSGghemWuZXHz[UBie3OjeTygTWM2OCB;IEG2MlMh|ryPLh?= NGHpWJI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEWzOFU{Pyd-MkS1N|Q2Ozd:L3G+
EAC NVvIRYpMS3m2b4TvfIlkcXS7IHHzd4F6 NFm1e3Q1QCCqcoO= MnLoR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgSWFEKGOnbHzzJIFnfGW{IES4JIhzeyCkeTD0dplx[W5iYnz1[UBmgGOudYPpc44h[XO|YYmsJGlEPTBiPTCxOk41KM7:TT6= NIDwWWU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEWzOFU{Pyd-MkS1N|Q2Ozd:L3G+
HeLa NV3aPWFlS3m2b4TvfIlkcXS7IHHzd4F6 MnLCOFghcHK| NX7OWHNQS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOi5|IN88UU4> NHm3fVk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEW0O|c6PCd-MkS1OFc4QTR:L3G+
HepG2 MXjDfZRwfG:6aXPpeJkh[XO|YYm= MlvCOFghcHK| Mor0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFcvPiEQvF2u MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDV2N{e5OEc,OjR3NEe3PVQ9N2F-
HCT116 NISzZWxEgXSxdH;4bYNqfHliYYPzZZk> M3zOXlQ5KGi{cx?= MUnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI1NjR|IN88UU4> NFfYUZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEW2OVkxPSd-MkS1OlU6ODV:L3G+
SKOV3 MV\DfZRwfG:6aXPpeJkh[XO|YYm= NYPYWldEPDhiaILz M2CxdGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNMV1Z|IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzPC52MzFOwG0v MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDV4NUmwOUc,OjR3NkW5NFU9N2F-
Bel7404 NHrXZnpEgXSxdH;4bYNqfHliYYPzZZk> MkDROFghcHK| MYLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDC[Yw4PDB2IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzPi56IN88UU4> MoDsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR3NkW5NFUoRjJ2NU[1PVA2RC:jPh?=
HepG2 NXzIcXpNS3m2b4TvfIlkcXS7IHHzd4F6 NXG1c3F4PDhiaILz NEKzcYZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOjZwOUig{txONg>? MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDV4NUmwOUc,OjR3NkW5NFU9N2F-
NCI-H460 MX3DfZRwfG:6aXPpeJkh[XO|YYm= M4H4eFQ5KGi{cx?= NV75XGJuS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVkOLLVi0OlAh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEO2MlA1KM7:TT6= M3z4WVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NU[1PVA2Lz5{NEW2OVkxPTxxYU6=
H3347 M1fQZWN6fG:2b4jpZ4l1gSCjc4PhfS=> MX23NkBpenN? MkSyR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTFM{PDdiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KEGuYX3hdkBDdHWnIHHzd4F6NCCLQ{WwJF0hOTFwNkSg{txONg>? M2T1bVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUizN|U2Lz5{NEW4N|M2PTxxYU6=
HT-29 M2TXOWN6fG:2b4jpZ4l1gSCjc4PhfS=> NFTa[Fk4OiCqcoO= NX7rcGJpS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUFRvMkmgZ4VtdHNiYYPz[ZN{\WRiYYOg[5Jwf3SqIHnubIljcXSrb36gZYZ1\XJiN{KgbJJ{KGK7IFHsZY1ieiCEbIXlJIF{e2G7LDDJR|UxKD1iMkSuPFch|ryPLh?= M1n3WFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUizN|U2Lz5{NEW4N|M2PTxxYU6=
DLD1 Mlq2R5l1d3SxeHnjbZR6KGG|c3H5 NWHKfndGPzJiaILz NVnVc5VVS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hTEyGMTDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nliQXzhcYFzKEKudXWgZZN{[XluIFnDOVAhRSB{OT6xOEDPxE1w M{L1XFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUizN|U2Lz5{NEW4N|M2PTxxYU6=
L1210 M1HBZmN6fG:2b4jpZ4l1gSCjc4PhfS=> MYK0PEBpenN? MljTR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgUFEzOTBiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxiboXtZoVzKGGodHXyJFQ5KGi{czDifUBk\WyuIHPveY51cW6pIHHzd4F6NCCLQ{WwJF0hOC5|MzFOwG0v M{XYfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NkOxN|U5Lz5{NE[zNVM2QDxxYU6=
HeLa NEfiXmlEgXSxdH;4bYNqfHliYYPzZZk> NEjMNJk4OiCqcoO= NGjJW3VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuIH71cYJmeiCjZoTldkA4OiCqcoOgZpkh[2WubDDjc5VvfGmwZzDhd5NigSxiSVO1NEA:KDBwNUSg{txONg>? NWrqUWw6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS2N|E{PThpPkK0OlMyOzV6PD;hQi=>
CCRF-CEM NGTwO4xEgXSxdH;4bYNqfHliYYPzZZk> NFXBfYE4OiCqcoO= MlHOR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR2NTTi2FRV2gZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygcpVu[mW{IHHmeIVzKDd{IHjyd{BjgSClZXzsJINwfW62aX7nJIF{e2G7LDDJR|UxKD1iMUig{txONg>? NYfuPY1pRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS2N|E{PThpPkK0OlMyOzV6PD;hQi=>
HeLa NEm4[IhEgXSxdH;4bYNqfHliYYPzZZk> M{fnblI1KGi{cx?= MUXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9vKGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyNjhizszNMi=> NFjZR2U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NE[0NVk4PSd-MkS2OFE6PzV:L3G+
MCF7 M1fQfGN6fG:2b4jpZ4l1gSCjc4PhfS=> MXeyOEBpenN? M4n5dWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhOjRiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFwODFOwG0v NHfqfo09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NE[0NVk4PSd-MkS2OFE6PzV:L3G+
A549 NInYVmtEgXSxdH;4bYNqfHliYYPzZZk> MoezNlQhcHK| M1XQfWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhOjRiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFwOTFOwG0v NY[yPG93RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS2OFE6PzVpPkK0OlQyQTd3PD;hQi=>
DU145 MWDDfZRwfG:6aXPpeJkh[XO|YYm= NU\QOJZuOjRiaILz MXTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDEWVE1PSClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkAzPCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOS57IN88UU4> NHXxUms9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NE[0NVk4PSd-MkS2OFE6PzV:L3G+
COLO205 MlvvR5l1d3SxeHnjbZR6KGG|c3H5 NWPhW2F1OjRiaILz M{PueWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNQVE9{MEWgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iC2dX3vdkBoem:5dHigZYZ1\XJiMkSgbJJ{NCCLQ{WwJF0hOy5|OTFOwG0v NEK3[pc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NE[1O|U3QCd-MkS2OVc2Pjh:L3G+
RPMI8226 MYXBcpRqdGW3a3XtbYMh[XO|YYm= MoLkNlQhcHK| MXvBcpRqdGW3a3XtbYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDSVG1KQDJ{NjDj[YxteyCjc4Pld5Nm\CCjczDpcohq[mm2aX;uJI9nKHS3bX;yJIdzd3e2aDDh[pRmeiB{NDDodpMtKEmFNUCgQUA{NjV3IN88UU4> MnH3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR4NUe1OlgoRjJ2NkW3OVY5RC:jPh?=
HCC2998 M4W1XGN6fG:2b4jpZ4l1gSCjc4PhfS=> M4PxblI1KGi{cx?= NHrRZpFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS0N{OUm4JINmdGy|IHHzd4V{e2WmIHHzJIlvcGmkaYTpc44hd2ZidIXtc5Ih\3Kxd4ToJIFnfGW{IEK0JIhzeyxiSVO1NEA:KDVwN{Wg{txONg>? MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDZ3N{W2PEc,OjR4NUe1Olg9N2F-
HCT15 MoLBR5l1d3SxeHnjbZR6KGG|c3H5 MVqyOEBpenN? NILtVYFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzNTDj[YxteyCjc4Pld5Nm\CCjczDpcohq[mm2aX;uJI9nKHS3bX;yJIdzd3e2aDDh[pRmeiB{NDDodpMtKEmFNUCgQUA3NjZzIN88UU4> NUDkR4ZvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS2OVc2PjhpPkK0OlU4PTZ6PD;hQi=>
KM12 MlL4R5l1d3SxeHnjbZR6KGG|c3H5 NYXwSldDOjRiaILz NVyyZ|hbS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hU01zMjDj[YxteyCjc4Pld5Nm\CCjczDpcohq[mm2aX;uJI9nKHS3bX;yJIdzd3e2aDDh[pRmeiB{NDDodpMtKEmFNUCgQUA4Njl2IN88UU4> NWraXGEyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS2OVc2PjhpPkK0OlU4PTZ6PD;hQi=>
SW620 MmPkR5l1d3SxeHnjbZR6KGG|c3H5 MVyyOEBpenN? M2Dkc2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNYPjJyIHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4YhfHWvb4Kg[5Jwf3SqIHHmeIVzKDJ2IHjyd{whUUN3MDC9JFE5NjZizszNMi=> Ml63QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR4NUe1OlgoRjJ2NkW3OVY5RC:jPh?=
NCI60 Mnr4R5l1d3SxeHnjbZR6KGG|c3H5 MojhNlQhcHK| MoXNR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUmNKPjBiY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kB1fW2xcjDndo94fGhiYX\0[ZIhOjRiaILzMEBKSzVyIE2gNlkvPSEQvF2u NHTaeZI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NE[1O|U3QCd-MkS2OVc2Pjh:L3G+
E0771 MU\DfZRwfG:6aXPpeJkh[XO|YYm= MmHDN{Bl[Xm| M4PuRWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KG2xdYPlJGUxPzdzIHPlcIx{KGGodHXyJFMh\GG7czDifUBUWkJiYYPzZZktKEmFNUCgQUAxNjJ6IN88UU4> M3LPWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{C0OlkyLz5{NEewOFY6OTxxYU6=
HT-29 M33VUWN6fG:2b4jpZ4l1gSCjc4PhfS=> NV;6N49LOyCmYYnz Mn;UR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQuOjliY3XscJMh[W[2ZYKgN{Bl[Xm|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFIvPThizszNMi=> NFO3UmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEewOFY6OSd-MkS3NFQ3QTF:L3G+
MCF7 NGfEVXREgXSxdH;4bYNqfHliYYPzZZk> MlTiN{Bl[Xm| NWnBbGZLS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA{KGSjeYOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hOi56NjFOwG0v MkfMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5MES2PVEoRjJ2N{C0OlkyRC:jPh?=
SW480 NIriepBEgXSxdH;4bYNqfHliYYPzZZk> NWDETXExOyCmYYnz NIj3PFlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUXzR6MDDj[YxteyCjZoTldkA{KGSjeYOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hOy54OTFOwG0v NHHUZWw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEewOFY6OSd-MkS3NFQ3QTF:L3G+
RKO MUTDfZRwfG:6aXPpeJkh[XO|YYm= MnnzN{Bl[Xm| NUXYcVZ7S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWkuRIHPlcIx{KGGodHXyJFMh\GG7czDifUBUWkJiYYPzZZktKEmFNUCgQUA1NjN7IN88UU4> MoHpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5MES2PVEoRjJ2N{C0OlkyRC:jPh?=
MCF10A M2DafmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVPDWI1xOyCmYYnz MlyxR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHOTCDIHPlcIx{KGGodHXyJFMh\GG7czDifUBUWkJiYYPzZZktKEmFNUCgQUA5NjB4IN88UU4> NWfGeohuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3NFQ3QTFpPkK0O|A1PjlzPD;hQi=>
CCD-18Co MVTDfZRwfG:6aXPpeJkh[XO|YYm= M1\1V|Mh\GG7cx?= M1TpOWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNETC1zOFPvJINmdGy|IHHmeIVzKDNiZHH5d{BjgSCVUlKgZZN{[XluIFnDOVAhRSB7LkK2JO69VS5? MoC0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5MES2PVEoRjJ2N{C0OlkyRC:jPh?=
T47D MXTDfZRwfG:6aXPpeJkh[XO|YYm= NVrsW25KOyCmYYnz Ml;sR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWFQ4TCClZXzsd{Bi\nSncjCzJIRigXNiYomgV3JDKGG|c3H5MEBKSzVyIE2gNVAvPTZizszNMi=> Mnf6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5MES2PVEoRjJ2N{C0OlkyRC:jPh?=
MDA-MB-231 MoLrR5l1d3SxeHnjbZR6KGG|c3H5 MV[zJIRigXN? NVjuPWU5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUSDLV3CMVI{OSClZXzsd{Bi\nSncjCzJIRigXNiYomgV3JDKGG|c3H5MEBKSzVyIE2gNVgvOTJizszNMi=> NXXoOJBqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3NFQ3QTFpPkK0O|A1PjlzPD;hQi=>
A549 MkXWR5l1d3SxeHnjbZR6KGG|c3H5 NG\JSW01QCCqcoO= M3nBNGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25ibXXhd5Vz\WRiYYSgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvQThizszNMi=> NEfqNWg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEeyO|Q3Oid-MkS3Nlc1PjJ:L3G+
HeLa MnPLR5l1d3SxeHnjbZR6KGG|c3H5 MlLtNkBl[Xm| M{W5XGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgNkBl[Xm|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFcvOzRizszNMi=> MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDd4N{izPUc,OjR5Nke4N|k9N2F-
MCF7 NYTGOYFoS3m2b4TvfIlkcXS7IHHzd4F6 M3XNUVIh\GG7cx?= MXrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEKg[IF6eyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNU42KM7:TT6= M3XoVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{[3PFM6Lz5{NEe2O|g{QTxxYU6=
HT-29 M3fIVGN6fG:2b4jpZ4l1gSCjc4PhfS=> NIPhO|czKGSjeYO= MVTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bi\nSncjCyJIRigXNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVcvOiEQvF2u NW\PbYRDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3Olc5OzlpPkK0O|Y4QDN7PD;hQi=>
A549 M{HlO2N6fG:2b4jpZ4l1gSCjc4PhfS=> NX7TT5VrOiCmYYnz M{TuVGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgNkBl[Xm|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQ1NjB3IN88UU4> NYHxfHdQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3Olc5OzlpPkK0O|Y4QDN7PD;hQi=>
A549 MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{LiZlQ5KGi{cx?= NXm5PIlOT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hPC53NTFOwG0v NEXx[lU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEe5O|c6QCd-MkS3PVc4QTh:L3G+
PC3 NVrPe3VtS3m2b4TvfIlkcXS7IHHzd4F6 MWO3NkBpenN? NUXIZ4EzS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWEN|IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1NjZ6IN88UU4> NV64UoZpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3PVgxQThpPkK0O|k5ODl6PD;hQi=>
MCF7 M4LnVmN6fG:2b4jpZ4l1gSCjc4PhfS=> NHvnNWo4OiCqcoO= NHnSd|hEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA4Njd4IN88UU4> MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDd7OEC5PEc,OjR5OUiwPVg9N2F-
MGC803 MXHDfZRwfG:6aXPpeJkh[XO|YYm= NHX0TYQ4OiCqcoO= M{e5b2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ISzhyMzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hQC5zMzFOwG0v Ml;6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5OUiwPVgoRjJ2N{m4NFk5RC:jPh?=
EC109 M4XYW2N6fG:2b4jpZ4l1gSCjc4PhfS=> MW[3NkBpenN? MV3DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDFR|ExQSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlQvOTRizszNMi=> M2K3NVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{m4NFk5Lz5{NEe5PFA6QDxxYU6=
MCF7 NIj4eJJCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NGDmbZQ4OiCqcoO= M{DpdmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNz6wPEDPxE1w NFH0T2k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEixPVk2Pid-MkS4NVk6PTZ:L3G+
HCT116 MkXERY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MWi3NkBpenN? MljiRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGwMlU1KM7:TT6= MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDhzOUm1Okc,OjR6MUm5OVY9N2F-
Bel7402 M3H0T2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NXPPN5dSPzJiaILz MXfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEKnbEe0NFIh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGxMlEzKM7:TT6= NHLsXW09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEixPVk2Pid-MkS4NVk6PTZ:L3G+
A549 MXTDfZRwfG:6aXPpeJkh[XO|YYm= M2HKV|I1KGi{cx?= MVnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxMlMh|ryPLh?= MmX4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6M{W2N|MoRjJ2OEO1OlM{RC:jPh?=
HeLa NU\O[JB2S3m2b4TvfIlkcXS7IHHzd4F6 MViyOEBpenN? MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxMlMh|ryPLh?= MmDQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6M{W2N|MoRjJ2OEO1OlM{RC:jPh?=
MCF7 MlfJR5l1d3SxeHnjbZR6KGG|c3H5 MkPINlQhcHK| MnrhR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjCyOEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNU41KM7:TT6= NXm3XYh2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS4N|U3OzNpPkK0PFM2PjN|PD;hQi=>
DU145 NW[0dW93S3m2b4TvfIlkcXS7IHHzd4F6 MVqyOEBpenN? MVXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDEWVE1PSClZXzsd{Bi\nSncjCyOEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNU42KM7:TT6= MmPsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6M{W2N|MoRjJ2OEO1OlM{RC:jPh?=
MCF7 NHnGZnZCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M4TG[lQ5KGi{cx?= MmG2RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|LkWyJO69VS5? MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDh|NUixO{c,OjR6M{W4NVc9N2F-
EC9706 NXrxZ5JlSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MmHmOFghcHK| MYDBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEWFOUewOkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iOT60OUDPxE1w NXG0[2lwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS4N|U5OTdpPkK0PFM2QDF5PD;hQi=>
MGC803 MXPBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MWO0PEBpenN? NWfhS|JOSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNS2M5ODNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEyNjN2IN88UU4> MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDh|NUixO{c,OjR6M{W4NVc9N2F-
L1210 MkToR5l1d3O2YYTpZ{Bi[3Srdnn0fUBie3OjeR?= M4HOcVQ5KGi{cx?= NVHGRYMxS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KG2xdYPlJGwyOjFyIHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4YheHKxbHnm[ZJifGmxbjDh[pRmeiB2ODDodpMh[nliQ3;1cJRmeiClZXzsJINwfW62aX7nJI1mfGixZDygTWM2OCB;IECuN|Mh|ryPLh?= NVHNZnhWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5NFY2OTBpPkK0PVA3PTFyPD;hQi=>
HeLa M4\rWWN6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= M1Kx[lczKGi{cx?= M1PJSWN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gdJJwdGmoZYLheIlwdiCjZoTldkA4OiCqcoOgZpkhS2:3bITldkBk\WyuIHPveY51cW6pIH3leIhw\CxiSVO1NEA:KDBwNUSg{txONg>? NYj5Z4FORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5NFY2OTBpPkK0PVA3PTFyPD;hQi=>
CEM MkXwR5l1d3O2YYTpZ{Bi[3Srdnn0fUBie3OjeR?= MoDEO|IhcHK| M1XFcWN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDwdo9tcW[ncnH0bY9vKGGodHXyJFczKGi{czDifUBEd3WudHXyJINmdGxiY3;1cpRqdmdibXX0bI9lNCCLQ{WwJF0hOThizszNMi=> MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDlyNkWxNEc,OjR7ME[1NVA9N2F-
PC3 NYnBUGdKS3m2b4TvfIlkcXS7IHHzd4F6 MnvCOFghcHK| Ml:zR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCLQ{WwJF0hOi5{IN88UU4> MojPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7MUC5O|QoRjJ2OUGwPVc1RC:jPh?=
HCT15 MXXDfZRwfG:6aXPpeJkh[XO|YYm= NXrVOYl3PDhiaILz M4DXPGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDF3IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDJR|UxKD1iND61JO69VS5? MojEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7MUC5O|QoRjJ2OUGwPVc1RC:jPh?=
HeLa NEnGRmlEgXSxdH;4bYNqfHliYYPzZZk> NUHUd21XPDhiaILz MWPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCLQ{WwJF0hPC57IN88UU4> Mk\UQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7MUC5O|QoRjJ2OUGwPVc1RC:jPh?=
WM266.4 M{D2RmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MVeyOEBpenN? NWXZeGtsSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDXUVI3Pi52IHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEeLNUCgQUAzQC55NjFOwG0v MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl|NEm5Nkc,OjR7M{S5PVI9N2F-
HeLa NVzEcmhWSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MUeyOEBpenN? M2TkcGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDh[pRmeiB{NDDodpMh[nliTWTUJIF{e2G7LDDHTVUxKD1iM{CuNlEh|ryPLh?= NXjk[HZlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5N|Q6QTJpPkK0PVM1QTl{PD;hQi=>
MDA-MB-231 NVjCTm9jSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NYr1b3h{PDhiaILz NFfvb5hCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi1{M{GgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJwNEWg{txONg>? NXj5cWJvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5OFEyOjlpPkK0PVQyOTJ7PD;hQi=>
HeLa NV7YdVZKSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M3L0RlQ5KGi{cx?= NX31TGV[SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyMlc5KM7:TT6= M{ewblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUSxNVI6Lz5{NEm0NVEzQTxxYU6=
KCL22 M3X3[GFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NEWwVZM1QCCqcoO= NFHZOJFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFvDUFIzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlUzKM7:TT6= MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl2MUGyPUc,OjR7NEGxNlk9N2F-
KB NUnFV|NlS3m2b4TvfIlkcXS7IHHzd4F6 Moq1OFghcHK| MoewR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT2Ih[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGuNlMh|ryPLh?= M4jVdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUWzNFI6Lz5{NEm1N|AzQTxxYU6=
HCT116 M1m4Z2N6fG:2b4jpZ4l1gSCjc4PhfS=> NWn1[oJOPDhiaILz M4T3[GN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDFzNjDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTBwMEWg{txONg>? MkHDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7NUOwNlkoRjJ2OUWzNFI6RC:jPh?=
HeLa M3LzWGN6fG:2b4jpZ4l1gSCjc4PhfS=> MVy0PEBpenN? M2r5bGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI{NjN|IN88UU4> M1jDVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUWzNFI6Lz5{NEm1N|AzQTxxYU6=
A549 M1qye2N6fG:2b4jpZ4l1gSCjc4PhfS=> MXy0PEBpenN? M2\BU2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFM1NjN2IN88UU4> NXO2PZp3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5OVMxOjlpPkK0PVU{ODJ7PD;hQi=>
HepG2 NHHPc|ZEgXSxdH;4bYNqfHliYYPzZZk> NXjUe4F{PDhiaILz NYfoeWFOS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN6LkO0JO69VS5? M2fMZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUWzNFI6Lz5{NEm1N|AzQTxxYU6=
CNE M2\Y[2N6fG:2b4jpZ4l1gSCjc4PhfS=> NXzoT5g1PDhiaILz M1ywSmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNPTSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOFUvOSEQvF2u NVTlO2FDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5OVMxOjlpPkK0PVU{ODJ7PD;hQi=>
NCI-H460 M{jMNWN6fG:2b4jpZ4l1gSCjc4PhfS=> M{Hv[FQ5KGi{cx?= MlLGR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUmNKNUh2NkCgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR3LkG0JO69VS5? NGn2eG09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm1N|AzQSd-MkS5OVMxOjl:L3G+
MGC803 MVrDfZRwfG:6aXPpeJkh[XO|YYm= MkLKOFghcHK| MlK3R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWdEQDB|IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1Pi57MzFOwG0v M{PBNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUWzNFI6Lz5{NEm1N|AzQTxxYU6=
A549 MnPNR5l1d3SxeHnjbZR6KGG|c3H5 MVu0PEBpenN? NUDBWYg5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygTWM2OCB;IESuNlEh|ryPLh?= NYO4WFF3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5OVY2PTJpPkK0PVU3PTV{PD;hQi=>
PC3 M1PRV2N6fG:2b4jpZ4l1gSCjc4PhfS=> NVPSelQyPDhiaILz NIfNTZNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFnDOVAhRSBzMjFOwG0v M1\QUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUW2OVUzLz5{NEm1OlU2OjxxYU6=
A549 MVjDfZRwfG:6aXPpeJkh[XO|YYm= NVPUN4NrOjRidH:gOFghcHK| MXnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9vKGGodHXyJFI1KHSxIES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCLQ{WwJF0hOS54NTFOwG0v NFX0bGs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm5OlE{QCd-MkS5PVYyOzh:L3G+
MGC803 M2fJT2FvfGmlYX7j[ZIh[XO|YYm= MUS3NkBpenN? MXzBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVfDPFA{KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlQ2KM7:TT6= NWXOe29uRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwNFE1QDJpPkK1NFAyPDh{PD;hQi=>
MCF7 NHrVXHNCdnSrY3HuZ4VzKGG|c3H5 NFmzXpk4OiCqcoO= NYDJe|lpSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFcvOTJizszNMi=> NXSwNoZrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwNFE1QDJpPkK1NFAyPDh{PD;hQi=>
EC9706 M123d2FvfGmlYX7j[ZIh[XO|YYm= M1\DV|czKGi{cx?= M1Xm[GFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDFR|k4ODZiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFgvODdizszNMi=> NV3Obm1ZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwNFE1QDJpPkK1NFAyPDh{PD;hQi=>
SSMC-7721 MorTRY51cWOjbnPldkBie3OjeR?= MUK3NkBpenN? MV3BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2PNR{04PzJzIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPS5yODFOwG0v M3vDblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MECxOFgzLz5{NUCwNVQ5OjxxYU6=
MDA-MB-231 NHf3cYREgXSxdH;4bYNqfHliYYPzZZk> M3zlWFQ5KGi{cx?= NV\iOYFMS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUSDLV3CMVI{OSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlQvPiEQvF2u MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTBzNkKzOEc,OjVyMU[yN|Q9N2F-
A549 NHH0RZhEgXSxdH;4bYNqfHliYYPzZZk> Mn;mOFghcHK| MXrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzOU41OSEQvF2u M1v6WlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MEG2NlM1Lz5{NUCxOlI{PDxxYU6=
MCF7 NX:1Z5B6S3m2b4TvfIlkcXS7IHHzd4F6 M2H4WlQ5KGi{cx?= M3f6XGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFM6Njh6IN88UU4> MnT0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyMU[yN|QoRjJ3MEG2NlM1RC:jPh?=
HepG2 M{[xPGN6fG:2b4jpZ4l1gSCjc4PhfS=> MoH2OFghcHK| MUfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOFYvQDNizszNMi=> MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTBzNkKzOEc,OjVyMU[yN|Q9N2F-
HCT116 MnnHR5l1d3SxeHnjbZR6KGG|c3H5 M2SzOVczKGi{cx?= NHLoTVlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzMU[gZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WUzDhd5NigSxiSVO1NEA:KDBwNTFOwG0v NUTXbXRxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwOlYzQDJpPkK1NFY3Ojh{PD;hQi=>
SW620 NV\4XHppS3m2b4TvfIlkcXS7IHHzd4F6 M4G5ZlczKGi{cx?= NH7CdYVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUXzZ{MDDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSVIHHzd4F6NCCLQ{WwJF0hPS5|IN88UU4> MkXrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyNk[yPFIoRjJ3ME[2NlgzRC:jPh?=
MCF7 MnzIRY51cWOjbnPldkBie3OjeR?= NIT6eY04OiCqcoO= NUmxTYtWSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBk\WyuIIDyc4xq\mW{YYTpc44h[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQvPiEQvF2u NWHZS5FMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwPFY6OTVpPkK1NFg3QTF3PD;hQi=>
EC9706 NUOxe4tRSW62aXPhcoNmeiCjc4PhfS=> NV73VXVkPzJiaILz NIDBNHVCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gSWM6PzB4IHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4Yh[2WubDDwdo9tcW[ncnH0bY9vKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1NjdizszNMi=> M3TMdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MEi2PVE2Lz5{NUC4OlkyPTxxYU6=
MGC803 MWDBcpRq[2GwY3XyJIF{e2G7 M1;5dVczKGi{cx?= NGDTdI5CdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWdEQDB|IHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4Yh[2WubDDwdo9tcW[ncnH0bY9vKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOCEQvF2u M2rWe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MEi2PVE2Lz5{NUC4OlkyPTxxYU6=
HeLa MXLBcpRq[2GwY3XyJIF{e2G7 NEPWd|c4OiCqcoO= Mk\6RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDj[YxtKHC{b3zp[oVz[XSrb36gZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGyJO69VS5? M1rPNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MEi2PVE2Lz5{NUC4OlkyPTxxYU6=
A549 NFTI[5pCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M1XLXFQ5KGi{cx?= NUWxNFJjSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDdwNkKg{txONg>? NIiwVm09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUGxN|g4Pyd-MkWxNVM5Pzd:L3G+
MGC803 MUjBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MUO0PEBpenN? MUHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2JQ{iwN{Bk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIHPlcIwhfmmjYnnsbZR6KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA4Njd4IN88UU4> NIPNZ2o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUGxN|g4Pyd-MkWxNVM5Pzd:L3G+
CNE M2LuUGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MYK0PEBpenN? NV;G[W1vSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDUmUh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTVwMEeg{txONg>? NIq4RYs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUGxN|g4Pyd-MkWxNVM5Pzd:L3G+
Bel7402 NYPEW242SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M{XDR|Q5KGi{cx?= NFLITpRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFLlcFc1ODJiY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUmuPFQh|ryPLh?= NVTBVpVHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWxNVM5PzdpPkK1NVE{QDd5PD;hQi=>
HepG2 Ml;kR5l1d3SxeHnjbZR6KGG|c3H5 MVq0PEBpenN? MXnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlkvQThizszNMi=> NH;0ZnA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUG1NVU5OCd-MkWxOVE2QDB:L3G+
HeLa MlzFR5l1d3SxeHnjbZR6KGG|c3H5 M3jn[lQ5KGi{cx?= NUDLc2tZS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOzVwM{Sg{txONg>? MkLYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVzNUG1PFAoRjJ3MUWxOVgxRC:jPh?=
SMMC-7404 M4TOcWN6fG:2b4jpZ4l1gSCjc4PhfS=> M36zUlQ5KGi{cx?= M4\YZmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNOVUNvN{SwOEBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNECuNlEh|ryPLh?= NHnVUGc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUG1NVU5OCd-MkWxOVE2QDB:L3G+
NCI-H460 M4T2emN6fG:2b4jpZ4l1gSCjc4PhfS=> MonCOFghcHK| M{m3Z2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KNE[wJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB2ND6wOEDPxE1w MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTF3MUW4NEc,OjVzNUG1PFA9N2F-
MGC803 Mo\BR5l1d3SxeHnjbZR6KGG|c3H5 NUjVbJhrPDhiaILz MmXzR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWdEQDB|IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1Pi57MzFOwG0v MoD0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVzNUG1PFAoRjJ3MUWxOVgxRC:jPh?=
B16 MlfrRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MmD5OFghcHK| M{HQTWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViQkG2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzNz64OUDPxE1w MnvLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVzNkS3OlIoRjJ3MU[0O|YzRC:jPh?=
HL60 Ml7TRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NEHi[I81QCCqcoO= Mn[5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKTE[wJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{Nz6wNUDPxE1w MkSyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVzNkS3OlIoRjJ3MU[0O|YzRC:jPh?=
Hep M1z5PWN6fG:2b4jpZ4l1gSCjc4PhfS=> MmTmOFghcHK| NV;YUog{S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyIHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAxNjVizszNMi=> NHrpZo49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUG3OlMzQSd-MkWxO|Y{Ojl:L3G+
IMR32 NWf5SFFRS3m2b4TvfIlkcXS7IHHzd4F6 NVvyZ3R7PDhiaILz MkXkR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTW1TOzJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFEvOyEQvF2u MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTF5NkOyPUc,OjVzN{[zNlk9N2F-
B16F10 MVTDfZRwfG:6aXPpeJkh[XO|YYm= NHLK[4s4OiCqcoO= MWjDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W|ZTDCNVZHOTBiY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBxem:uaX\ldoF1cW:wIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLki3JO69VS5? NEGxZ|A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUG4NFkzPSd-MkWxPFA6OjV:L3G+
MGC803 MUPDfZRwfG:6aXPpeJkh[XO|YYm= NH3DUVM4OiCqcoO= M1mwcWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ISzhyMzDj[YxteyCjc4Pld5Nm\CCjczDpcohq[mm2aX;uJI9nKHC{b3zp[oVz[XSrb36gZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEeuOlkh|ryPLh?= NUfUXHFYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWxPFA6OjVpPkK1NVgxQTJ3PD;hQi=>
MCF7 MWjDfZRwfG:6aXPpeJkh[XO|YYm= Mn7iO|IhcHK| M3flXWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBxem:uaX\ldoF1cW:wIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB6LkmzJO69VS5? NIfBd409[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUG4NFkzPSd-MkWxPFA6OjV:L3G+
EC109 Ml;PR5l1d3SxeHnjbZR6KGG|c3H5 M2e0bFczKGi{cx?= NHO2W5BEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBGSzFyOTDj[YxteyCjc4Pld5Nm\CCjczDpcohq[mm2aX;uJI9nKHC{b3zp[oVz[XSrb36gZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGwMlgyKM7:TT6= M1rVNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MUiwPVI2Lz5{NUG4NFkzPTxxYU6=
HEK293 NEn1SW1CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NHq1OYEzPCCqcoO= M1jSZ2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgTGVMOjl|IHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1QC55IN88UU4> M{TDSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MUm4PVk4Lz5{NUG5PFk6PzxxYU6=
Bel7402 M{OyVWN6fG:2b4jpZ4l1gSCjc4PhfS=> NWrZW3FXQTZiaILz M4DSZWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGJmdDd2MEKgZ4VtdHNiYYPz[ZN{\WRiYYOg[5Jwf3SqIHnubIljcXSrb36gdoF1\SCjZoTldkA6PiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOi5{MzFOwG0v M1PzNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MkCzO|g{Lz5{NUKwN|c5OzxxYU6=
HCT8 NXX4W4xrS3m2b4TvfIlkcXS7IHHzd4F6 MX:5OkBpenN? NGq3dJNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1R6IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIILheIUh[W[2ZYKgPVYhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFMvPTRizszNMi=> MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTJyM{e4N{c,OjV{MEO3PFM9N2F-
C33A MVzDfZRwfG:6aXPpeJkh[XO|YYm= MUS5OkBpenN? MmP1R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR|M{SSClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiC{YYTlJIFnfGW{IEm2JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0MlYyKM7:TT6= M1:xTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MkCzO|g{Lz5{NUKwN|c5OzxxYU6=
A549 NH7jdZdEgXSxdH;4bYNqfHliYYPzZZk> NXLBdHJYQTZiaILz MonBR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiC{YYTlJIFnfGW{IEm2JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC2MlY6KM7:TT6= NE\1TG49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUKwN|c5Oyd-MkWyNFM4QDN:L3G+
A549 MWjDfZRwfG:6aXPpeJkh[XO|YYm= Ml[wOFghcHK| MmXHR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gNE4xOSEQvF2u Ml;tQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV{NUm1NVUoRjJ3MkW5OVE2RC:jPh?=
THP1 Ml7oR5l1d3SxeHnjbZR6KGG|c3H5 M4T2XFQ5KGi{cx?= NWTldG5XS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hXEiSMTDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hOC5yNDFOwG0v M4XvTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MkW5OVE2Lz5{NUK1PVUyPTxxYU6=
EAC NFXCS4VEgXSxdH;4bYNqfHliYYPzZZk> MXe0PEBpenN? M3TodWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KG2xdYPlJGVCSyClZXzsd{Bi\nSncjC0PEBpenNiYomgeJJ6eGGwIHLseYUh\HmnIHX4Z4x2e2mxbjDt[ZRpd2RuIFnDOVAhRSBzND62JO69VS5? MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTJ4MUiyOUc,OjV{NkG4NlU9N2F-
DLA MWPDfZRwfG:6aXPpeJkh[XO|YYm= NYizRmRSPDhiaILz MnnZR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgSGxCKGOnbHzzJIFnfGW{IES4JIhzeyCkeTD0dplx[W5iYnz1[UBlgWViZYjjcJV{cW:wIH3leIhw\CxiSVO1NEA:KDF3LkOg{txONg>? M1zFXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3Mk[xPFI2Lz5{NUK2NVgzPTxxYU6=
EAC NI[1R|REgXSxdH;4bYNqfHliYYPzZZk> NEO2fVY1QCCqcoO= M4[0UWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KG2xdYPlJGVCSyClZXzsd{Bi\nSncjC0PEBpenNiYomgUGRJKHKnbHXhd4Uh[XO|YYmsJGlEPTBiPTCxOU41KM7:TT6= MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTJ4MUiyOUc,OjV{NkG4NlU9N2F-
DLA M2PrWGN6fG:2b4jpZ4l1gSCjc4PhfS=> NVzmWIlyPDhiaILz Ml\2R5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgSGxCKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gNVUvPiEQvF2u NXXvXJJrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWyOlE5OjVpPkK1NlYyQDJ3PD;hQi=>
EAC M2\qfmN6fG:2b4jpZ4l1gSCjc4PhfS=> NWPLe5NKPDhiaILz MmfGR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgSWFEKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gNVYvOyEQvF2u NV;IWopGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWyOlE5OjVpPkK1NlYyQDJ3PD;hQi=>
DLA NHrCdoZEgXSxdH;4bYNqfHliYYPzZZk> MmX3OFghcHK| NFe4ZmJEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBFVEFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JGxFUCC{ZXzlZZNmKGG|c3H5MEBKSzVyIE2gNVYvQCEQvF2u Mm\CQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV{NkG4NlUoRjJ3Mk[xPFI2RC:jPh?=
L1210 NFvGS2dEgXSxc4TheIlkKGGldHn2bZR6KGG|c3H5 NGjzSoE1QCCqcoO= Mn35R5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JI1wfXOnIFyxNlExKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDDc5VtfGW{IHPveY51cW6pLDDJR|UxKD1iMD6zN{DPxE1w MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTR|NUS3NUc,OjV2M{W0O|E9N2F-
HeLa M2HwN2N6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= NIjze404OiCqcoO= MkXmR5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IFPveYx1\XJiY3;1cpRqdmduIFnDOVAhRSB{Lk[g{txONg>? NYXubpcyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW0N|U1PzFpPkK1OFM2PDdzPD;hQi=>
CEM MnPuR5l1d3O2YYTpZ{Bi[3Srdnn0fUBie3OjeR?= NInjNlc4OiCqcoO= M2THXWN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IFPveYx1\XJiY3;1cpRqdmduIFnDOVAhRSBzODFOwG0v MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTR|NUS3NUc,OjV2M{W0O|E9N2F-
SMMC7721 NIjhbnpCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MVzBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOPTVO3O|IyKGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCCycn;sbYZmemG2aX;uJIJ6KEOFS{igZZN{[XluIFnDOVAhRSB3Lk[yJO69VS5? MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTR2MkOwN{c,OjV2NEKzNFM9N2F-
A549 NFS3bnRCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MVHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEF3NEmgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iClZXzsJJBzd2yrZnXyZZRqd25iYomgR2NMQCCjc4PhfUwhUUN3MDC9JFgvOTNizszNMi=> MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTR2MkOwN{c,OjV2NEKzNFM9N2F-
MCF7 NY\NNVM6SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NVnFUVRTSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCCycn;sbYZmemG2aX;uJIJ6KEOFS{igZZN{[XluIFnDOVAhRSBzND6yOkDPxE1w NYDafVJuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW0OFI{ODNpPkK1OFQzOzB|PD;hQi=>
LoVo M1HWRmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NFLJN2I1QCCqcoO= M4jmTmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTH;Wc{Bk\WyuczDhd5Nme3OnZDDhd{Bk\WyuLXfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMj63JO69VS5? NYjoW|ZvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW0OVM4QTRpPkK1OFU{Pzl2PD;hQi=>
MCF7 NXXQTVg5SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NWT4fZRLPDhiaILz MnLMRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHzd4V{e2WmIHHzJINmdGxvZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF4LkOg{txONg>? NXHPVXNmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW0OVM4QTRpPkK1OFU{Pzl2PD;hQi=>
HeLa M2q4TmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MWq0PEBpenN? NEPsZWlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZZN{\XO|ZXSgZZMh[2WubD3ndo94fGhiaX7obYJqfGmxbjDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUiuNUDPxE1w NX\jWHdbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW0OVM4QTRpPkK1OFU{Pzl2PD;hQi=>
BGC823 NGnJZmxCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NUfVfY1uPDhiaILz MW\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEKJQ{iyN{Bk\WyuczDhd5Nme3OnZDDhd{Bk\WyuLXfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|NT62JO69VS5? NWTRPGxTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW0OVM4QTRpPkK1OFU{Pzl2PD;hQi=>
HCT116 NYrxeIMzSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= Mk\XOFghcHK| MnPIRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZZN{\XO|ZXSgZZMh[2WubD3ndo94fGhiaX7obYJqfGmxbjDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iM{[uNkDPxE1w NFr4UXQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUS1N|c6PCd-MkW0OVM4QTR:L3G+
U87 MYDBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MVy0PEBpenN? MX7BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFV6NzDj[YxteyCjc4Pld5Nm\CCjczDj[YxtNWe{b4f0bEBqdmirYnn0bY9vKGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{QC5{IN88UU4> MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTR3M{e5OEc,OjV2NUO3PVQ9N2F-
MGC803 M2XYXWN6fG:2b4jpZ4l1gSCjc4PhfS=> MkDkOFghcHK| NUP1fW5nS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUeFOECzJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|MD60OUDPxE1w NW\SOphuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW0OlIzPTNpPkK1OFYzOjV|PD;hQi=>
NCI-H460 M2XHZmN6fG:2b4jpZ4l1gSCjc4PhfS=> NYS4WlA3PDhiaILz M37J[WN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KNE[wJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|Nj6wOEDPxE1w NHTQbo49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUS2NlI2Oyd-MkW0OlIzPTN:L3G+
HeLa NFvTeYFEgXSxdH;4bYNqfHliYYPzZZk> MXm0PEBpenN? MljsR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|YvPTNizszNMi=> M4LlfFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3NE[yNlU{Lz5{NUS2NlI2OzxxYU6=
MCF7 M1TlSGFvfGmlYX7j[ZIh[XO|YYm= NULXXYJ2PDhiaILz NVrPRmhrSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI3NjlizszNMi=> NGexPVU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUS2NlI3PCd-MkW0OlIzPjR:L3G+
GES-1 M1L4XmN6fG:2b4jpZ4l1gSCjc4PhfS=> MV[0PEBpenN? NEnqdmtEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBITVNvMTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOzBwOTFOwG0v NGTMNlU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUS2NlI3PCd-MkW0OlIzPjR:L3G+
K562 MVHBcpRq[2GwY3XyJIF{e2G7 NUXlOWJIPDhiaILz NX2zelhYSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGs2PjJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFMyNjZizszNMi=> NIW4[mE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUS2NlI3PCd-MkW0OlIzPjR:L3G+
HCT116 NXX1fY1jS3m2b4TvfIlkcXS7IHHzd4F6 NXP1WXo{PzJiaILz MUnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFYh|ryPLh?= Ml6xQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV2NkKyO|coRjJ3NE[yNlc4RC:jPh?=
T47D MXnDfZRwfG:6aXPpeJkh[XO|YYm= M3XCR|czKGi{cx?= NFvPbpNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBVPDeGIHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUA4NjlizszNMi=> NHrqRlA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUS2NlI4Pyd-MkW0OlIzPzd:L3G+
HuH7 MlnCR5l1d3SxeHnjbZR6KGG|c3H5 MVK3NkBpenN? M4ixNWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGh2UDdiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFMxNjdizszNMi=> M2m3[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3NE[yNlc4Lz5{NUS2NlI4PzxxYU6=
MCF7 M2XndmN6fG:2b4jpZ4l1gSCjc4PhfS=> NGLTfZo1QCCqcoO= Ml3ER5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bie3Onc4Pl[EBieyClZXzsJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IES4JIhzeyCkeTDXV3QuOSCjc4PhfUwhUUN3MDC9JFM1NjR6IN88UU4> MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTR4NkG5Okc,OjV2Nk[xPVY9N2F-
SKBR3 MYXDfZRwfG:6aXPpeJkh[XO|YYm= MYm0PEBpenN? NVLZUVBGS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0uEUkOgZ4VtdHNib4\ldoV5eHKnc4PpcochUEWUMjDhd5Nme3OnZDDhd{Bk\WyuIHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDR6IHjyd{BjgSCZU2StNUBie3OjeTygTWM2OCB;IEO4Mlg5KM7:TT6= M2\OTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3NE[2NVk3Lz5{NUS2OlE6PjxxYU6=
B16 NF72T2hEgXSxdH;4bYNqfHliYYPzZZk> NVLMOYhzPDhiaILz M{TmRmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KG2xdYPlJGIyPiClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJN2en[rdnHsJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC3MlY1KM7:TT6= NG\4ZYg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUWwOlcyQCd-MkW1NFY4OTh:L3G+
MKN28 MXzDfZRwfG:6aXPpeJkh[XO|YYm= M2\0OFQ5KGi{cx?= NIrQ[5BEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOU05{ODDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKHO3co\peoFtKGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA6NjZ5IN88UU4> NIr1c5k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUWwOlcyQCd-MkW1NFY4OTh:L3G+
HeLa NH23cXNEgXSxdH;4bYNqfHliYYPzZZk> M{LKcFQ5KGi{cx?= MXPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygd5Vzfmm4YXygZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGzMlQ2KM7:TT6= NUTIe|VFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW1NFY4OThpPkK1OVA3PzF6PD;hQi=>
HeLa MV3BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M4exSVczKGi{cx?= MmDQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZVzhJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB7LkC5JO69VS5? MlewQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV3Mkm3OFIoRjJ3NUK5O|QzRC:jPh?=
SF763 MonuRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M{DUdlczKGi{cx?= NETDTIxCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPGO|Y{KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC5MlM1KM7:TT6= MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTV{OUe0Nkc,OjV3Mkm3OFI9N2F-
HL60 NEDnbGNCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NHGwUIE4OiCqcoO= MVHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiONkCgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFyLkS1JO69VS5? NIPmbXE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUWyPVc1Oid-MkW1Nlk4PDJ:L3G+
B16 MmLGRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NXLPZ5h{PzJiaILz MnPLRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDtc5V{\SCEMU[gZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFyLkWyJO69VS5? NW\4RlNDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW1Nlk4PDJpPkK1OVI6PzR{PD;hQi=>
Bel7402 NYj3eW1JSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MVu3NkBpenN? M2m2XWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQnXsO|QxOiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVEvPzhizszNMi=> NFftNIs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUWyPVc1Oid-MkW1Nlk4PDJ:L3G+
MGC803 MWXDfZRwfG:6aXPpeJkh[XO|YYm= NEDNXXk1QCCqcoO= NF\WfFFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOT0N6MEOgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDNwN{Gg{txONg>? M3PuU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3NUW0PVIzLz5{NUW1OFkzOjxxYU6=
Bcap37 M3;vRmN6fG:2b4jpZ4l1gSCjc4PhfS=> M1\BdlQ5KGi{cx?= MWrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDCZ4FxOzdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFUvOThizszNMi=> MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTV3NEmyNkc,OjV3NUS5NlI9N2F-
SGC7901 NYXlO4xbS3m2b4TvfIlkcXS7IHHzd4F6 NXfDXlBlPDhiaILz NXXOZ5dRS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0eFN{mwNUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNj61OkDPxE1w MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTV3NEmyNkc,OjV3NUS5NlI9N2F-
BALB/3T3 Ml\VRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NVjlOZBMPzJiaILz M1rnb2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViQlHMRk8{XDNiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KFOUQjDt[ZRpd2RuIFnDOVAhRSB|LkKzJO69VS5? M13vSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3NkS0Olc1Lz5{NU[0OFY4PDxxYU6=
LoVo M3WxSmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 Ml3BO|IhcHK| M37BOWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTH;Wc{Bk\WyuczDhd5Nme3OnZDDhd{Boem:5dHigbY5pcWKrdHnvckBi\nSncjC3NkBpenNiYomgV3JDKG2ndHjv[EwhUUN3MDC9JFQvPjlizszNMi=> MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTZ2NE[3OEc,OjV4NES2O|Q9N2F-
doxorubicin-resistant LoVo/DX NIiyUnNCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M{TZVVczKGi{cx?= Mnz3RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCmb4jvdpVjcWOrbj3y[ZNqe3SjboSgUI9Xdy:GWDDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nliU2LCJI1mfGixZDygTWM2OCB;IE[g{txONg>? M2H2RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3NkS0Olc1Lz5{NU[0OFY4PDxxYU6=
SW707 MlHqRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MVy3NkBpenN? NWrhS49WSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|cxPyClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkA4OiCqcoOgZpkhW1KEIH3leIhw\CxiSVO1NEA:KDJyLkS2JO69VS5? M3n0V|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3NkS0Olc1Lz5{NU[0OFY4PDxxYU6=
vincristine-resistant HL60/Vinc NXnjeYFpSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NXe3e|ZwPzJiaILz Ml3BRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiC4aX7jdol{fGmwZT3y[ZNqe3SjboSgTGw3OC:YaX7jJINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyNU4yPSEQvF2u NYnESXNNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW2OFQ3PzRpPkK1OlQ1Pjd2PD;hQi=>
HL60 NUHk[4hsSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NWnNeYV4PzJiaILz NUKwZmJMSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIUFYxKGOnbHzzJIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9vKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzOi53NDFOwG0v MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTZ2NE[3OEc,OjV4NES2O|Q9N2F-
HT-29 MmrCRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M3vqbVczKGi{cx?= MVPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiWLUK5JINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IEeyJIhzeyCkeTDTVmIhdWW2aH;kMEBKSzVyIE2gNlUvODhizszNMi=> NVHZZ5MzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW2OFQ3PzRpPkK1OlQ1Pjd2PD;hQi=>
LS180 NUPYXGxESW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MUe3NkBpenN? MkDORY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCOU{G4NEBk\WyuczDhd5Nme3OnZDDhd{Boem:5dHigbY5pcWKrdHnvckBi\nSncjC3NkBpenNiYomgV3JDKG2ndHjv[EwhUUN3MDC9JFM5Njl{IN88UU4> M4[2W|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3NkS0Olc1Lz5{NU[0OFY4PDxxYU6=
B16F10 MnPTRY51cWOjbnPldkBie3OjeR?= MWK3NkBpenN? NX7yboRXSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KG2xdYPlJGIyPkZzMDDj[YxteyCjc4Pld5Nm\CCjczDpcohq[mm2aX;uJI9nKHC{b3zp[oVz[XSrb36gZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGuOFMh|ryPLh?= Mn21QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV4NUW3NVgoRjJ3NkW1O|E5RC:jPh?=
MGC803 MV3BcpRq[2GwY3XyJIF{e2G7 NIC1XXo4OiCqcoO= MVPBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVfDPFA{KGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gdJJwdGmoZYLheIlwdiCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hQC52MzFOwG0v MofWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV4NUW3NVgoRjJ3NkW1O|E5RC:jPh?=
MCF7 MYrBcpRq[2GwY3XyJIF{e2G7 Mo\GO|IhcHK| NV\5ZYNoSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBxem:uaX\ldoF1cW:wIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB7LkGyJO69VS5? MofSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV4NUW3NVgoRjJ3NkW1O|E5RC:jPh?=
EC109 MWPBcpRq[2GwY3XyJIF{e2G7 MnnHO|IhcHK| MYrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iRVOxNFkh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDwdo9tcW[ncnH0bY9vKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOS54MTFOwG0v NHPtbXE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NU[1OVcyQCd-MkW2OVU4OTh:L3G+
HCT8 NIDtbINCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M320TlczKGi{cx?= NWnkbWNISW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3Q5KGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCCycn;sbYZmemG2aX;uJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlkyKM7:TT6= M{f4ZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3Nke1NVQ1Lz5{NU[3OVE1PDxxYU6=
HCT8 M1zUXGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M2\vVVczKGi{cx?= NV;SRYNXSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEA2NU[XIILld4l{fGGwdDDoeY1idiCKQ2S4JINmdGy|IHHzd4V{e2WmIHHzJIlvcGmkaYTpc44hd2ZiY3XscEBxem:uaX\ldoF1cW:wIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|Nj62N|gh|ryPLh?= M2fy[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3Nke1NVQ1Lz5{NU[3OVE1PDxxYU6=
MGC803 Ml64R5l1d3SxeHnjbZR6KGG|c3H5 MWG3NkBpenN? M{CydGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ISzhyMzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTBwN{Kg{txONg>? MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTdyN{CxNkc,OjV5MEewNVI9N2F-
MCF7 MofvR5l1d3SxeHnjbZR6KGG|c3H5 NX7qNVlsPzJiaILz NEezPWJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOi5{NDFOwG0v MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTdyN{CxNkc,OjV5MEewNVI9N2F-
EC9706 NVv3W41lS3m2b4TvfIlkcXS7IHHzd4F6 NXTyOo5kPzJiaILz NIntWFBEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBGSzl5ME[gZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF3Lk[3JO69VS5? MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTdyN{CxNkc,OjV5MEewNVI9N2F-
SMMC7721 NX;ZTpJVS3m2b4TvfIlkcXS7IHHzd4F6 MXG3NkBpenN? NXPuXI5uS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW02PQ{e3NlEh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKwMlQh|ryPLh?= MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTdyN{CxNkc,OjV5MEewNVI9N2F-
SW1573 NIXYSpVCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NIK0S2o1QCCqcoO= MVvBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOZMUW3N{Bk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFQvOyEQvF2u M3\vOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3N{WyOVI2Lz5{NUe1NlUzPTxxYU6=
HBL100 MmnVRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MVy0PEBpenN? NUDuOGlMSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIRmwyODBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB3LkWg{txONg>? NV3o[oJpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW3OVI2OjVpPkK1O|UzPTJ3PD;hQi=>
HeLa NGLUXJBCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MXO0PEBpenN? MXTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEinTHGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCxOUDPxE1w NFHrVGM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUe1NlUzPSd-MkW3OVI2OjV:L3G+
T47D NYDC[nRySW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M37ZXlQ5KGi{cx?= NIXvS5pCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGS0O2Qh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUA1PyEQvF2u M1q1d|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3N{WyOVI2Lz5{NUe1NlUzPTxxYU6=
WiDr NEj3OYVCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M3XOUFQ5KGi{cx?= NFroVnJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGfpSJIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUA1QSEQvF2u Ml3WQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV5NUK1NlUoRjJ3N{WyOVI2RC:jPh?=
MGC803 NWPFeHh5SW62aXPhcoNmeiCjc4PhfS=> M1Pac|Q5KGi{cx?= MWrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVfDPFA{KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygd5Vzfmm4YXygZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOuOVgh|ryPLh?= NUfKfHBmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4NVI6PjZpPkK1PFEzQTZ4PD;hQi=>
SMMC7721 MmPvRY51cWOjbnPldkBie3OjeR?= NHfVb4k1QCCqcoO= M3\6WmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTUW1EPzd{MTDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKHO3co\peoFtKGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1Njh5IN88UU4> MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPThzMkm2Okc,OjV6MUK5OlY9N2F-
HepG2 NVHXd5F5SW62aXPhcoNmeiCjc4PhfS=> M3y1c|Q5KGi{cx?= NVrOdmpKSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGG|c3Xzd4VlKGG|IHPlcIwhe3W{dnn2ZYwh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFUvQDZizszNMi=> MnT0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6MUK5OlYoRjJ3OEGyPVY3RC:jPh?=
SGC7901 NV\uV2RVSW62aXPhcoNmeiCjc4PhfS=> MUm0PEBpenN? M3XZdmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTS2M4QTBzIHPlcIx{KGG|c3Xzd4VlKGG|IHPlcIwhe3W{dnn2ZYwh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFYvOTJizszNMi=> M2W1OVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEGyPVY3Lz5{NUixNlk3PjxxYU6=
SKOV3 NWLBXYZvS3m2b4TvfIlkcXS7IHHzd4F6 NEDzSFgzKGSjeYO= M1W2VmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNMV1Z|IHPlcIx{KGGodHXyJFIh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUAzPy5|NDFOwG0v MoPxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6NEGxPVYoRjJ3OESxNVk3RC:jPh?=
HepG2 M3HzUWN6fG:2b4jpZ4l1gSCjc4PhfS=> NYfr[lA{OiCmYYnz MVLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjCyJIRigXNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|EvQThizszNMi=> NHj1b|I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUi0NVE6Pid-MkW4OFEyQTZ:L3G+
A549 MmHNR5l1d3SxeHnjbZR6KGG|c3H5 NXnsUZJbOiCmYYnz NYT1O|RPS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkAzKGSjeYOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOzhwMkOg{txONg>? M1zhblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OESxNVk3Lz5{NUi0NVE6PjxxYU6=
T24 NIPOTFVEgXSxdH;4bYNqfHliYYPzZZk> MnLuNkBl[Xm| MnS0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWFI1KGOnbHzzJIFnfGW{IEKg[IF6eyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0NE42PyEQvF2u NWrldnNURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4OFEyQTZpPkK1PFQyOTl4PD;hQi=>
SPCA2 NYPJb5JOS3m2b4TvfIlkcXS7IHHzd4F6 M1KyS|Ih\GG7cx?= NHfG[4NEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUWEODMjDj[YxteyCjZoTldkAzKGSjeYOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPDRwMTFOwG0v MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh2MUG5Okc,OjV6NEGxPVY9N2F-
NCI-H460 MYLDfZRwfG:6aXPpeJkh[XO|YYm= MmKzNkBl[Xm| M1P0PWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KNE[wJINmdGy|IHHmeIVzKDJiZHH5d{BjgSCPVGSgZZN{[XluIFnDOVAhRSB2Nj6xOUDPxE1w MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh2MUG5Okc,OjV6NEGxPVY9N2F-
MGC803 M3LKRmN6fG:2b4jpZ4l1gSCjc4PhfS=> NF3EeHMzKGSjeYO= NITsT4pEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOT0N6MEOgZ4VtdHNiYX\0[ZIhOiCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR5LkO5JO69VS5? MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh2MUG5Okc,OjV6NEGxPVY9N2F-
HCT116 MkGxR5l1d3SxeHnjbZR6KGG|c3H5 NV3NOJhyPDhiaILz NVvWZoJ7S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHzd4V{e2WmIHHzJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{OT61PEDPxE1w Mly5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6NEGxPVkoRjJ3OESxNVk6RC:jPh?=
HepG2 NIezWotEgXSxdH;4bYNqfHliYYPzZZk> MX[0PEBpenN? MYrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|AvPzlizszNMi=> MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh2MUG5PUc,OjV6NEGxPVk9N2F-
A549 MnPrR5l1d3SxeHnjbZR6KGG|c3H5 MX20PEBpenN? MlrhR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|YvOzRizszNMi=> NEXhW3A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUi0NVE6QSd-MkW4OFEyQTl:L3G+
T24 NILXXWxEgXSxdH;4bYNqfHliYYPzZZk> NEC3dpg1QCCqcoO= M1r2UWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHQzPCClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|cvPTZizszNMi=> MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh2MUG5PUc,OjV6NEGxPVk9N2F-
MGC803 MVrDfZRwfG:6aXPpeJkh[XO|YYm= NHjQXGw1QCCqcoO= NEDzZ3FEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOT0N6MEOgZ4VtdHNiYYPz[ZN{\WRiYYOgZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDRyLkm0JO69VS5? MnLsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6NEGxPVkoRjJ3OESxNVk6RC:jPh?=
MDA-MB-231 NEexZm1EgXSxdH;4bYNqfHliYYPzZZk> MkL2OFghcHK| MkXOR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNT64NkDPxE1w NG\ObWQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUi3NFE{OSd-MkW4O|AyOzF:L3G+
DU145 NFzndZJEgXSxdH;4bYNqfHliYYPzZZk> NUG4NJNmPDhiaILz NF[wU5pEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBFXTF2NTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPi5|NzFOwG0v MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh5MEGzNUc,OjV6N{CxN|E9N2F-
A549 Ml2wR5l1d3SxeHnjbZR6KGG|c3H5 Ml;wOFghcHK| NH3PT5pEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA4NjVzIN88UU4> M4q2[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEewNVMyLz5{NUi3NFE{OTxxYU6=
A549 Mk\mRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MlK4O|IhcHK| NH;PXVlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IGfTWFgh[XO|YYmsJGlEPTBiPTCyMlgh|ryPLh?= M2HGSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OUG5NFUzLz5{NUmxPVA2OjxxYU6=
PANC1 MYTBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M3;IeVczKGi{cx?= MUTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFCDTlOxJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCZU2S4JIF{e2G7LDDJR|UxKD1iMz63JO69VS5? NV3XOVFVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW5NVkxPTJpPkK1PVE6ODV{PD;hQi=>
PSN1 MlGyRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NUDLcWlTPzJiaILz NUX4d5FzSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQV24yKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDXV3Q5KGG|c3H5MEBKSzVyIE2gOE41KM7:TT6= NWHiN3FDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW5NVkxPTJpPkK1PVE6ODV{PD;hQi=>
MDA-MB-231 MkTnRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NYjUbnMzPzJiaILz MX\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2GQT3NRk0zOzFiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JHdUXDhiYYPzZZktKEmFNUCgQUA2NjJizszNMi=> MnLzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV7MUmwOVIoRjJ3OUG5NFUzRC:jPh?=
HeLa NV7OS4JySW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NETXd4c4OiCqcoO= M4TOWGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDh[pRmeiB5MjDodpMh[nliV2PUPEBie3OjeTygTWM2OCB;IEWuPEDPxE1w MoDYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV7MUmwOVIoRjJ3OUG5NFUzRC:jPh?=
TIG3 NVPNUYdFSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MnS1O|IhcHK| NGfWcWtCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGTJS|Mh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IGfTWFgh[XO|YYmsJGlEPTBiPTC4MlQh|ryPLh?= M17Hc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OUG5NFUzLz5{NUmxPVA2OjxxYU6=
HeLa NWXLd5VRSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NU\ncGVkPDhiaILz M2TOOWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIHPlcIwheHKxbHnm[ZJifGmxbjDpcoN2[mG2ZXSg[o9zKDR6IHjyd{BjgSCFQ1u4JIF{e2G7LDDJR|UxKD1iOD65N{DPxE1w NXrI[FFIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW5OVk5OTNpPkK1PVU6QDF|PD;hQi=>
MCF7 NUPZOW5OSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NVXqVJpTPDhiaILz NWDrVVh2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCCycn;sbYZmemG2aX;uJIlv[3WkYYTl[EBnd3JiNEigbJJ{KGK7IFPDT|gh[XO|YYmsJGlEPTBiPTC5MlU3KM7:TT6= M{H2WlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OUW5PFE{Lz5{NUm1PVgyOzxxYU6=
Bel7402 NEX2NI9CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M3XnOVQ5KGi{cx?= M1L2NGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQnXsO|QxOiClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJINmdGxicILvcIln\XKjdHnvckBqdmO3YnH0[YQh\m:{IES4JIhzeyCkeTDDR2s5KGG|c3H5MEBKSzVyIE2gNVkvQTFizszNMi=> M1jYclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OUW5PFE{Lz5{NUm1PVgyOzxxYU6=
NIH/3T3 NFLpU5dCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NVHCco9mPDhiaILz MlTFRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDtc5V{\SCQSVivN3Q{KGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCCycn;sbYZmemG2aX;uJIlv[3WkYYTl[EBnd3JiNEigbJJ{KGK7IFPDT|gh[XO|YYmsJGlEPTBiPTCyNk4{PiEQvF2u NEnTS3U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUm1PVgyOyd-MkW5OVk5OTN:L3G+
A549 MnvmRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NIXtTHE1QCCqcoO= NITXV2xCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDj[YxtKHC{b3zp[oVz[XSrb36gbY5kfWKjdHXkJIZweiB2ODDodpMh[nliQ1PLPEBie3OjeTygTWM2OCB;IESwMlM5KM7:TT6= NEj3VGw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUm1PVgyOyd-MkW5OVk5OTN:L3G+
HepG2 Ml7MR5l1d3SxeHnjbZR6KGG|c3H5 NFXoflA1QCCqcoO= M{XBbWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA5KM7:TT6= NEX2R4Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUm2PVE4OSd-MkW5OlkyPzF:L3G+
L1210 NEW5dHlEgXSxdH;4bYNqfHliYYPzZZk> Ml23R5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgUFEzOTBiY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBk\WyuIIDyc4xq\mW{YYTpc44tKEmFNUCgQUAxNjN|IN88UU4> M37mNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MECxN|Q1Lz5{NkCwNVM1PDxxYU6=
HeLa MUXDfZRwfG:6aXPpeJkh[XO|YYm= NH;x[WJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4Yh[2WubDDwdo9tcW[ncnH0bY9vNCCLQ{WwJF0hOC53NDFOwG0v NV;GUYpGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[wNFE{PDRpPkK2NFAyOzR2PD;hQi=>
CEM NUDiRZZxS3m2b4TvfIlkcXS7IHHzd4F6 MnX3R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR2VOKGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCCycn;sbYZmemG2aX;uMEBKSzVyIE2gNVgh|ryPLh?= M1jJPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MECxN|Q1Lz5{NkCwNVM1PDxxYU6=
PC3 NYnibllbS3m2b4TvfIlkcXS7IHHzd4F6 MVu0PEBpenN? MXXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZZN{\XO|ZXSgZZMh\3Kxd4ToJIlvcGmkaYTpc44h[W[2ZYKgOFghcHK|IHL5JJN2dHCqb4Loc4RidWmwZTDCJIF{e2G7LDDJR|UxKD1iMj6yJO69VS5? NXvOZnpJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[yNlI1PDlpPkK2NlIzPDR7PD;hQi=>
HCT116 MVLDfZRwfG:6aXPpeJkh[XO|YYm= M4qxfVQ5KGi{cx?= MYPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPDhiaILzJIJ6KHO3bIDoc5Jpd2SjbXnu[UBDKGG|c3H5MEBKSzVyIE2gOE42KM7:TT6= NE\UUXM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkKyNlQ1QSd-Mk[yNlI1PDl:L3G+
A549 NY\Ub25vS3m2b4TvfIlkcXS7IHHzd4F6 M4q5XlQ5KGi{cx?= NGHSbFFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDR6IHjyd{BjgSC|dXzwbI9zcG:mYX3pcoUhSiCjc4PhfUwhUUN3MDC9JFQvQSEQvF2u NFfPWFE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkKyNlQ1QSd-Mk[yNlI1PDl:L3G+
HCT8 MV;DfZRwfG:6aXPpeJkh[XO|YYm= MnnNO|IhcHK| MnvJR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVQCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOk4{KM7:TT6= MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjJ{N{e3O{c,OjZ{Mke3O|c9N2F-
Bel7402 M1ftdGN6fG:2b4jpZ4l1gSCjc4PhfS=> NFLONnM4OiCqcoO= MYTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDC[Yw4PDB{IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOC5yNzFOwG0v NFHWTlM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkKyO|c4Pyd-Mk[yNlc4Pzd:L3G+
A549 NFTEbXZEgXSxdH;4bYNqfHliYYPzZZk> NFvVcYU4OiCqcoO= NULuUnZ2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTRwMUWg{txONg>? MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjJ{N{e3O{c,OjZ{Mke3O|c9N2F-
HepG2 MVzDfZRwfG:6aXPpeJkh[XO|YYm= M1KyTVczKGi{cx?= NHHiRVdEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTZwNEKg{txONg>? MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjJ{N{e3O{c,OjZ{Mke3O|c9N2F-
A549 NYDzRZV2SW62aXPhcoNmeiCjc4PhfS=> NVnJWG9pPDhiaILz MY\BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEBoem:5dHigbY5kfWKjdHXkJIZweiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMj6xN{DPxE1w NWnVdFRmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[yN|ExQDBpPkK2NlMyODhyPD;hQi=>
MCF7 NVjpbXcySW62aXPhcoNmeiCjc4PhfS=> M2H2WlQ5KGi{cx?= NHi0ZnlCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCCpcn;3eIghcW6ldXLheIVlKG[xcjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNk4{PiEQvF2u MmWwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ{M{GwPFAoRjJ4MkOxNFgxRC:jPh?=
HeLa MYnBcpRq[2GwY3XyJIF{e2G7 NIDVXIc1QCCqcoO= NWrM[|FbSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxiZ4Lve5RpKGmwY4XiZZRm\CCob4KgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQvPiEQvF2u MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjJ|MUC4NEc,OjZ{M{GwPFA9N2F-
HaCaT MYHDfZRwfG:6aXPpeJkh[XO|YYm= NV;SR3FpPDhiaILz NF7wTYhEgXSxdH;4bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIZWNiXCClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCCpcn;3eIghcW6ldXLheIVlKG[xcjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUvOjZizszNMi=> NETVeGI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkKzNVA5OCd-Mk[yN|ExQDB:L3G+
Hep3B M1LTXmN6fG:2b4jpZ4l1gSCjc4PhfS=> MWiyJIRigXN? M4fibmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeDOEIHPlcIx{KGG|c3Xzd4VlKGG|IHnu[JVkfGmxbjDv[kBk\WyuIHTlZZRpKGmwY4XiZZRm\CCob4KgNkBl[Xm|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEvPSEQvF2u NFHWcpQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkK1PVgxOid-Mk[yOVk5ODJ:L3G+
Bcap37 NH\4bpdEgXSxdH;4bYNqfHliYYPzZZk> Mn7CNkBl[Xm| NFHXXWlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBD[2GyM{egZ4VtdHNiYYPz[ZN{\WRiYYOgbY5lfWO2aX;uJI9nKGOnbHyg[IVifGhiaX7jeYJifGWmIH\vdkAzKGSjeYOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPS53ODFOwG0v NFfDc2g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkK1PVgxOid-Mk[yOVk5ODJ:L3G+
MCF7 M3LDWWN6fG:2b4jpZ4l1gSCjc4PhfS=> MUGyJIRigXN? NGPKRmNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGG|c3Xzd4VlKGG|IHnu[JVkfGmxbjDv[kBk\WyuIHTlZZRpKGmwY4XiZZRm\CCob4KgNkBl[Xm|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEyNjVizszNMi=> MlfDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ{NUm4NFIoRjJ4MkW5PFAzRC:jPh?=
HepG2 MojDR5l1d3SxeHnjbZR6KGG|c3H5 M{XORlIh\GG7cx?= NF[1e|FEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjc4Pld5Nm\CCjczDpcoR2[3Srb36gc4Yh[2WubDDk[YF1cCCrbnP1ZoF1\WRiZn;yJFIh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUA1OC5|NDFOwG0v NFu5TVM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkK1PVgxOid-Mk[yOVk5ODJ:L3G+
A549 NWDafYp2S3m2b4TvfIlkcXS7IHHzd4F6 MU[yJIRigXN? MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGmwZIXjeIlwdiCxZjDj[YxtKGSnYYToJIlv[3WkYYTl[EBnd3JiMjDkZZl{KGK7IF3UWEBie3OjeTygTWM2OCB;IES0MlA2KM7:TT6= MoDXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ{NUm4NFIoRjJ4MkW5PFAzRC:jPh?=
SW620 NHTTUpRCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NIDoRlE4OiCqcoO= NIj1eZNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPXOlIxKGOnbHzzJIlv[3WkYYTl[EBnd3JiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuO|kh|ryPLh?= NIHmNpU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkK5NVA{QCd-Mk[yPVExOzh:L3G+
MIAPaCa2 Ml3pRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NFG5SIw4OiCqcoO= NVTY[mtQSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNTWFR[UOjMjDj[YxteyCrbnP1ZoF1\WRiZn;yJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOS54NzFOwG0v NU\IPJk3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[yPVExOzhpPkK2NlkyODN6PD;hQi=>
MCF7 NG\xWG1CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MVS0PEBpenN? M12xXGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNT6wNVIh|ryPLh?= M3f4NFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4M{CxOVU5Lz5{NkOwNVU2QDxxYU6=
DU145 NH;2cJBCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M2rXZ|Q5KGi{cx?= NWHRSHFqSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDEWVE1PSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOk4xPzJizszNMi=> M2HQWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4M{CxOVU5Lz5{NkOwNVU2QDxxYU6=
A549 NGXqb4lCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= Ml;2OFghcHK| MX3BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEF3NEmgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDdwMkS0JO69VS5? MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjNyMUW1PEc,OjZ|MEG1OVg9N2F-
HeLa M13LNGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MmHtOFghcHK| MXzBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEinTHGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDhwM{G3JO69VS5? NVfXO4EzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[zNFE2PThpPkK2N|AyPTV6PD;hQi=>
MCF7 M2m5[WN6fG:2b4jpZ4l1gSCjc4PhfS=> NH7vVJg1QCCqcoO= M1v3V2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE6NjN7IN88UU4> NV3NPIl3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[zOlM5PjlpPkK2N|Y{QDZ7PD;hQi=>
A549 M1[5OmN6fG:2b4jpZ4l1gSCjc4PhfS=> NULVOZJbPDhiaILz NFnER25EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzOi5{ODFOwG0v MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjN4M{i2PUc,OjZ|NkO4Olk9N2F-
PC3 MU\DfZRwfG:6aXPpeJkh[XO|YYm= NGXPfJA1QCCqcoO= M4nJ[mN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHBEOyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlIvPjNizszNMi=> M3S5V|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4M{[zPFY6Lz5{NkO2N|g3QTxxYU6=
HepG2 NFHOS4pEgXSxdH;4bYNqfHliYYPzZZk> NXvNOYo2PDhiaILz NYDTd3ZMS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR4LkizJO69VS5? M1W3flxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4M{[zPFY6Lz5{NkO2N|g3QTxxYU6=
HT-29 M3jFNGN6fG:2b4jpZ4l1gSCjc4PhfS=> M4[zOFQ5KGi{cx?= MUTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkA1QCCqcoOgZpkhX1OWLUGgZZN{[XluIFnDOVAhRSBzNT64N{DPxE1w M3K2dlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NEGzO|I2Lz5{NkSxN|czPTxxYU6=
PA1 NIjlZ2tCdnSrY3HuZ4VzKGG|c3H5 M2P2UVQ5KGi{cx?= MVvBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUFGxJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB5LkW5JO69VS5? NEL1V5Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkSxN|czPid-Mk[0NVM4OjZ:L3G+
BT549 NEG0c5ZCdnSrY3HuZ4VzKGG|c3H5 M3\NfFQ5KGi{cx?= NFvrVGZCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gRnQ2PDliY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE6Njh{IN88UU4> M2XzPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NEGzO|I3Lz5{NkSxN|czPjxxYU6=
DU145 NIi5NZNCdnSrY3HuZ4VzKGG|c3H5 M{HrRVQ5KGi{cx?= MknsRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFTVNVQ2KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzPU4yPyEQvF2u MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjRzM{eyOkc,OjZ2MUO3NlY9N2F-
MDA-MB-231 NEHPb|JCdnSrY3HuZ4VzKGG|c3H5 MYS0PEBpenN? MnXZRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi1{M{GgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR3LkSzJO69VS5? NETEXXU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkSxN|czPid-Mk[0NVM4OjZ:L3G+
SH-SY5Y MnTURY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NHPVb4w4OiCqcoO= NIXCUVFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPIMXN[PVliY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXC2kYYPl[EBOd3OvYX7uJIF{e2G7IILlcIF1cX[nIITvJINwdnS{b3ysJGdKPTBiPTCxMlUh|ryPLh?= MlPNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ3M{m2NlYoRjJ4NUO5OlI3RC:jPh?=
Caco2 MUjBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MV23NkBpenN? NHzjbolCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFPhZ48zKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQu[mG|ZXSgUY9{dWGwbjDhd5NigSC{ZXzheIl3\SC2bzDjc451em:uLDDHTVUxKD1iMj6yJO69VS5? Mlj0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ3M{m2NlYoRjJ4NUO5OlI3RC:jPh?=
A549 MmLDRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M370W|czKGi{cx?= M3L5VGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNj63OkDPxE1w NInQRlE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkW5OVE5PCd-Mk[1PVUyQDR:L3G+
SGC7901 MmmyRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M{fFb|czKGi{cx?= Mn3hRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVR1O3PVAyKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNU46KM7:TT6= Mm\XQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ3OUWxPFQoRjJ4NUm1NVg1RC:jPh?=
MDA-MB-435S NEe5d4pCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MnXwO|IhcHK| M2LnSGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTR|NWOgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF3LkG5JO69VS5? M2\PblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NUm1NVg1Lz5{NkW5OVE5PDxxYU6=
L02 MU\DfZRwfG:6aXPpeJkh[XO|YYm= M2fsSlczKGi{cx?= MXjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDMNFIh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEK1Mlkh|ryPLh?= MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjV7NUG4OEc,OjZ3OUWxPFQ9N2F-
PC3 MXXBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M3yxS|czKGi{cx?= MlroRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCSQ{OgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR{LkWg{txONg>? M13rb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NUm1NVg1Lz5{NkW5OVE5PDxxYU6=
PANC1 M2HTU2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NWrnZnJ7PzJiaILz MnrFRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCSQV7DNUBk\WyuczDh[pRmeiB5MjDodpMh[nliV2PUMVgh[XO|YYmsJGlEPTBiPTCwMlQh|ryPLh?= MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjZyNkG0NEc,OjZ4ME[xOFA9N2F-
MDA-MB-231 MWnBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MlX4O|IhcHK| MnrmRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPRFGtUWIuOjNzIHPlcIx{KGGodHXyJFczKGi{czDifUBYW1RvODDhd5NigSxiSVO1NEA:KDFwMTFOwG0v NXrKUWxYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[2NFYyPDBpPkK2OlA3OTRyPD;hQi=>
HeLa NVjjN4t7SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MYm3NkBpenN? NYPENHZXSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDXV3QuQCCjc4PhfUwhUUN3MDC9JFYvPCEQvF2u NUK3SXZjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[2NFYyPDBpPkK2OlA3OTRyPD;hQi=>
PSN1 MXrBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NGr6TJg4OiCqcoO= M{TMOmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUGPONUBk\WyuczDh[pRmeiB5MjDodpMh[nliV2PUMVgh[XO|YYmsJGlEPTBiPTC4Mlch|ryPLh?= NIfBTmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Nk[wOlE1OCd-Mk[2NFYyPDB:L3G+
A549 MofJRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MYW3NkBpenN? NETNXo9CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IGfTWE05KGG|c3H5MEBKSzVyIE2gPUDPxE1w NWPhRmRSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[2NFYyPDBpPkK2OlA3OTRyPD;hQi=>
MCF7 NFfGOYtCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NGTMeGE4OiCqcoO= NVjqWo57SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlA6KM7:TT6= M3j4SlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NkG3PVcxLz5{Nk[xO|k4ODxxYU6=
SW620 MoXIRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MX[3NkBpenN? MUDBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOZNkKwJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLke5JO69VS5? MnPFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ4MUe5O|AoRjJ4NkG3PVcxRC:jPh?=
A549 NVv3Z4VOS3m2b4TvfIlkcXS7IHHzd4F6 NIfCcoVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGG|c3Xzd4VlKGG|IHPlcIwh\3Kxd4ToJIlvcGmkaYTpc44h[nliTWTUJIF{e2G7LDDJR|UxKD1iMT6xJO69VS5? NGj6OlE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Nk[yPVg3OSd-Mk[2Nlk5PjF:L3G+
Neuro2a MWPDfZRwfG:6aXPpeJkh[XO|YYm= MoTjR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgUoV2em9{YTDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKGe{b4f0bEBqdmirYnn0bY9vKGK7IF3UWEBie3OjeTygTWM2OCB;IEGuNkDPxE1w MmXWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ4Mkm4OlEoRjJ4NkK5PFYyRC:jPh?=
HeLa MWjDfZRwfG:6aXPpeJkh[XO|YYm= NF\QfW1EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGG|c3Xzd4VlKGG|IHPlcIwh\3Kxd4ToJIlvcGmkaYTpc44h[nliTWTUJIF{e2G7LDDJR|UxKD1iMT61JO69VS5? M{jKcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NkK5PFYyLz5{Nk[yPVg3OTxxYU6=
COLO205 M2TO[WN6fG:2b4jpZ4l1gSCjc4PhfS=> M1q4NGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNQVE9{MEWgZ4VtdHNiYYPz[ZN{\WRiYYOgZ4VtdCCpcn;3eIghcW6qaXLpeIlwdiCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxMlgh|ryPLh?= NXTpNJpkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[2Nlk5PjFpPkK2OlI6QDZzPD;hQi=>
A549 NXXPVYg6SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NF7DWm84OiCqcoO= Mn3aRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDNUS5JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGOgZZN{[XluIFnDOVAhRSB|LkWyJO69VS5? NEHEO|E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkewN|c6PSd-Mk[3NFM4QTV:L3G+
HCT116 NH:ydWNCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M{\Sd|czKGi{cx?= M{HSdmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPUNVE3KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHMh[XO|YYmsJGlEPTBiPTC1MlU{KM7:TT6= MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjdyM{e5OUc,OjZ5MEO3PVU9N2F-
HT-29 MWDBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NHzWSFk4OiCqcoO= NF;aN2NCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjUMVI6KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHMh[XO|YYmsJGlEPTBiPTCyOE42KM7:TT6= NVrURYdSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[3NFM4QTVpPkK2O|A{Pzl3PD;hQi=>
MCF7 M{DmSmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MUW3NkBpenN? NHW4SG9CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlch[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UV{Bie3OjeTygTWM2OCB;IEOyMlE5KM7:TT6= NYPGT|Y3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[3NFM4QTVpPkK2O|A{Pzl3PD;hQi=>
HeLa NV7Ic4c{SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NULDPHpnPzJiaILz MnXSRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZVzhJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGOgZZN{[XluIFnDOVAhRSB2Mz63NUDPxE1w NXy3TVRqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[3NFM4QTVpPkK2O|A{Pzl3PD;hQi=>
SKOV3 NXW4cXBMS3m2b4TvfIlkcXS7IHHzd4F6 NHvLOnY1QCCqcoO= NYXmZ4J{S3m2b4TvfIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2tQXjNiY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBk\WyuIHfyc5d1cCCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOjJwNEOg{txONg>? MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjdyNkO0PUc,OjZ5ME[zOFk9N2F-
HCT116 NUTGR4d4S3m2b4TvfIlkcXS7IHHzd4F6 MXS0PEBpenN? MVvDfZRwfG:6aXOgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDj[YxtKGe{b4f0bEBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlQvPThizszNMi=> NH7KO4k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkewOlM1QSd-Mk[3NFY{PDl:L3G+
Bel7404 NY\HeoxZS3m2b4TvfIlkcXS7IHHzd4F6 MW[0PEBpenN? NF\QSG5EgXSxdH;4bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDC[Yw4PDB2IHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4Yh[2WubDDndo94fGhiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDNyLkKzJO69VS5? M165cFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4N{C2N|Q6Lz5{NkewOlM1QTxxYU6=
A549 MUfDfZRwfG:6aXPpeJkh[XO|YYm= M1fETFQ5KGi{cx?= M1iwWGN6fG:2b4jpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDj[YxtKGe{b4f0bEBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|EvOzNizszNMi=> NITpe3M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkewOlM1QSd-Mk[3NFY{PDl:L3G+
NCI-H460 NIqxUY5EgXSxdH;4bYNqfHliYYPzZZk> M1\ESlQ5KGi{cx?= M4rjNGN6fG:2b4jpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7DTU1JPDZyIHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4Yh[2WubDDndo94fGhiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN3LkWyJO69VS5? MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjdyNkO0PUc,OjZ5ME[zOFk9N2F-
MDST8 NW\Wb41DS3m2b4TvfIlkcXS7IHHzd4F6 MljyO|IhcHK| NGLoVFREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOTFOWODDj[YxteyCjZoTldkA4OiCqcoOgZpkhS0ONODDhd5NigSxiSVO1NEA:KDBwME[0JO69VS5? MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjd{NUCyPUc,OjZ5MkWwNlk9N2F-
MCF7 MlruR5l1d3SxeHnjbZR6KGG|c3H5 NEPvfmo4OiCqcoO= NXjnb2k1S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA4OiCqcoOgZpkhS0ONODDhd5NigSxiSVO1NEA:KDBwNUKg{txONg>? Mn62QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ5MkWwNlkoRjJ4N{K1NFI6RC:jPh?=
KM12 Mn\KR5l1d3SxeHnjbZR6KGG|c3H5 MkfROFghcHK| NFXsOXVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMVTF{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDJR|UxKD1iMUSuPEDPxE1w NXK1SG83RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[3NlczOTVpPkK2O|I4OjF3PD;hQi=>
HT-29 MX7DfZRwfG:6aXPpeJkh[XO|YYm= NF3NU4Y1QCCqcoO= M{DpS2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhVNTJ7IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDJR|UxKD1iMUSuPEDPxE1w Mn3hQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ5MkeyNVUoRjJ4N{K3NlE2RC:jPh?=
HCC2998 Mo\xR5l1d3SxeHnjbZR6KGG|c3H5 MmrHOFghcHK| MmHuR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNEOjl7ODDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygTWM2OCB;IEG0Mlgh|ryPLh?= Mn\qQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ5MkeyNVUoRjJ4N{K3NlE2RC:jPh?=
COLO205 NEDRRVVEgXSxdH;4bYNqfHliYYPzZZk> M2HqTlQ5KGi{cx?= MV\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDU2xQOjB3IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDJR|UxKD1iMUSuPEDPxE1w NIPGb4I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkeyO|IyPSd-Mk[3NlczOTV:L3G+
HCT116 NYTpcnN7S3m2b4TvfIlkcXS7IHHzd4F6 NWruXVF4PDhiaILz NGfhZ5FEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzMU[gZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGlEPTBiPTCxOE45KM7:TT6= NFvX[5Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkeyO|IyPSd-Mk[3NlczOTV:L3G+
HCT15 MWjDfZRwfG:6aXPpeJkh[XO|YYm= MYm0PEBpenN? M1LUUmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDF3IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDJR|UxKD1iMUSuPEDPxE1w MkfjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ5MkeyNVUoRjJ4N{K3NlE2RC:jPh?=
SW620 M2WzdWN6fG:2b4jpZ4l1gSCjc4PhfS=> NGHVPIo1QCCqcoO= MV\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTW|YzOCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiSVO1NEA:KDF2Lkig{txONg>? MnfEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ5MkeyNVUoRjJ4N{K3NlE2RC:jPh?=
MCF7 M4\leGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NYnKUZk1QTZiaILz NGHuT2pCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlch[2WubIOgZZN{\XO|ZXSgZZMh[2WubIXsZZIhTE6DIHPvcpRmdnRiYX\0[ZIhQTZiaILzJIJ6KEO7UWXBUnQhVkZiZnz1c5Jme2OnbnPlJIF{e2G7LDDJR|UxKD1iMD65JO69VS5? NHqyWmM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkezNVMxOCd-Mk[3N|E{ODB:L3G+
PC3 M3LTUmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MorkO|IhcHK| M{H0WmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUFOzJINmdGy|IHHzd4V{e2WmIHHzJINmdGy3bHHyJGRPSSClb370[Y51KGGodHXyJFczKGi{czDifUBEgVGXQV7UJG5HKG[udX;y[ZNk\W6lZTDhd5NigSxiSVO1NEA:KDRwOTFOwG0v NV20TXA4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[3N|E{ODBpPkK2O|MyOzByPD;hQi=>
HT-29 M1j6b2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 M4exVlczKGi{cx?= NXi2SJg5SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bie3Onc4Pl[EBieyClZXzseYxieiCGTlGgZ49vfGWwdDDh[pRmeiB5MjDodpMh[nliQ4nRWWFPXCCQRjDmcJVwemW|Y3XuZ4Uh[XO|YYmsJGlEPTBiPTC1MlMh|ryPLh?= MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjd|MUOwNEc,OjZ5M{GzNFA9N2F-
T84 M1HSR2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NYTKbm1mQTZiaILz NY\BUotPSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDUPFQh[2WubIOgZZN{\XO|ZXSgZZMh[2WubIXsZZIhTE6DIHPvcpRmdnRiYX\0[ZIhQTZiaILzJIJ6KEO7UWXBUnQhVkZiZnz1c5Jme2OnbnPlJIF{e2G7LDDJR|UxKD1iNj6yJO69VS5? NYDWNpR[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[3N|E{ODBpPkK2O|MyOzByPD;hQi=>
PC3 MV7DfZRwfG:6aXPpeJkh[XO|YYm= NILTZmw4OiCqcoO= NIH0fpNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFwNESg{txONg>? Mn;1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ5M{W5NFkoRjJ4N{O1PVA6RC:jPh?=
A549 MnPSR5l1d3SxeHnjbZR6KGG|c3H5 NHnZW2o4OiCqcoO= NWHjWnh6S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz60O{DPxE1w MniwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ5M{W5NFkoRjJ4N{O1PVA6RC:jPh?=
U87MG NIH6d25EgXSxdH;4bYNqfHliYYPzZZk> MoHGO|IhcHK| MmnUR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWVg4VUdiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDNwNkGg{txONg>? MmnsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ5M{W5NFkoRjJ4N{O1PVA6RC:jPh?=
L929 M3fCNWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NX33VFRkPDhiaILz M1jmSGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViTEmyPUBk\WyuczDh[pRmeiB2ODDodpMh[nliQ1PLPEBie3OjeTygTWM2OCB;IEKuPVgh|ryPLh?= M1e5SFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4N{i2Olk5Lz5{Nke4OlY6QDxxYU6=
SMMC7721 MWjBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M{nCN|Q5KGi{cx?= MVXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOPTVO3O|IyKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDDR2s5KGG|c3H5MEBKSzVyIE2gOU43OiEQvF2u NU\MZnVzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[3PFY3QThpPkK2O|g3Pjl6PD;hQi=>
A549 NGC4W5lCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MUS0PEBpenN? NULQSXN[SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDDR2s5KGG|c3H5MEBKSzVyIE2gPE4yOyEQvF2u NWXGUpYzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[3PFY3QThpPkK2O|g3Pjl6PD;hQi=>
HeLa Mn7JRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MnvEOFghcHK| MXTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEinTHGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KEOFS{igZZN{[XluIFnDOVAhRSBzNz6yNUDPxE1w MmDQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ5OE[2PVgoRjJ4N{i2Olk5RC:jPh?=
A549 MWfDfZRwfG:6aXPpeJkh[XO|YYm= MoizOFghcHK| M1juc2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEvPCEQvF2u MoHLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ6NUSzO|UoRjJ4OEW0N|c2RC:jPh?=
THP1 M2fWPWN6fG:2b4jpZ4l1gSCjc4PhfS=> MYW0PEBpenN? NHz0WYlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBVUFBzIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyNjdizszNMi=> MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjh3NEO3OUc,OjZ6NUSzO|U9N2F-
MCF7 NWTkWnNmS3m2b4TvfIlkcXS7IHHzd4F6 NGS0Uok1QCCqcoO= MVzDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyJO69VS5? MortQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ6NUSzO|UoRjJ4OEW0N|c2RC:jPh?=
HCT116 NVi3TplRS3m2b4TvfIlkcXS7IHHzd4F6 NUjrPJRkPDhiaILz NXywbnlDS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{LkOg{txONg>? NGC0b2o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Nki1OFM4PSd-Mk[4OVQ{PzV:L3G+
HCT8 NXPTXlJsS3m2b4TvfIlkcXS7IHHzd4F6 MWS0PEBpenN? M{HEd2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDhiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN{LkOxJO69VS5? NEDtfY89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Nki3N|QyPid-Mk[4O|M1OTZ:L3G+
WI38 M{DIcGN6fG:2b4jpZ4l1gSCjc4PhfS=> MWC0PEBpenN? M4rGT2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHdKOzhiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN6LkmxJO69VS5? Mmj6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ6N{O0NVYoRjJ4OEezOFE3RC:jPh?=
HepG2 MXzDfZRwfG:6aXPpeJkh[XO|YYm= MWe0PEBpenN? M1HkcmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB2MT62NkDPxE1w MmHjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ6N{O0NVYoRjJ4OEezOFE3RC:jPh?=
Hep3B M4PqTmN6fG:2b4jpZ4l1gSCjc4PhfS=> NIDQdoI1QCCqcoO= NYLqZ|hqS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyM1KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFyLkWzJO69VS5? NWTVVolURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[4PFMyPDhpPkK2PFg{OTR6PD;hQi=>
A549 M1vHOGN6fG:2b4jpZ4l1gSCjc4PhfS=> MojDOFghcHK| NHLBNmhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{PC5{NzFOwG0v Ml3nQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ6OEOxOFgoRjJ4OEizNVQ5RC:jPh?=
MCF7 MoTJR5l1d3SxeHnjbZR6KGG|c3H5 M1\TZVQ5KGi{cx?= NWf2WVN[S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPDJwN{ig{txONg>? M2q1OVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4OEizNVQ5Lz5{Nki4N|E1QDxxYU6=
Bcap37 NYTjSo1rS3m2b4TvfIlkcXS7IHHzd4F6 M2XublQ5KGi{cx?= NF3wblVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBD[2GyM{egZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR5LkC5JO69VS5? M2TUbVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4OEizNVQ5Lz5{Nki4N|E1QDxxYU6=
HepG2 MXnDfZRwfG:6aXPpeJkh[XO|YYm= NEXCVno1QCCqcoO= Mn70R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQ6Njd{IN88UU4> NUnyU4s2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[4PFMyPDhpPkK2PFg{OTR6PD;hQi=>
MCF7 NVfqS|I6SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MojSO|IhcHK| M4LzT2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDhd5Nme3OnZDDhd{Bk\WyuII\pZYJqdGm2eTDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMk[uNVQh|ryPLh?= MlSzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ7MkKyNlMoRjJ4OUKyNlI{RC:jPh?=
HeLa MkLGRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NWSyboo3PzJiaILz MYLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEinTHGgZ4VtdHNiYYPz[ZN{\WRiYYOgZ4VtdCC4aXHibYxqfHliYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ4LkG4JO69VS5? M{TITVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4OUKyNlI{Lz5{NkmyNlIzOzxxYU6=
HL60 M1\Vc2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NF\xfnQ4OiCqcoO= MYXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiONkCgZ4VtdHNiYYPz[ZN{\WRiYYOgZ4VtdCC4aXHibYxqfHliYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ5LkSzJO69VS5? NHzMd409[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkmyNlIzOyd-Mk[5NlIzOjN:L3G+
HCT116 NE\sboFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NWjTO|NNPzJiaILz M1vPcWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPUNVE3KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzPE4{KM7:TT6= MnG5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ7MkKyNlMoRjJ4OUKyNlI{RC:jPh?=
HepG2 MorORY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NUHuZ40zPzJiaILz NELtVlFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0PU4xOiEQvF2u MmDwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ7MkKyNlMoRjJ4OUKyNlI{RC:jPh?=
HT-29 MVHBcpRq[2GwY3XyJIF{e2G7 NUXScYFLPzJiaILz MoKxRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjUMVI6KGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCCpcn;3eIgh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFYvOyEQvF2u NGP4OIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkmyNlI{Oyd-Mk[5NlIzOzN:L3G+
RKO NX;tPZBUSW62aXPhcoNmeiCjc4PhfS=> M3XEfVczKGi{cx?= NHfrZVlCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gVmtQKGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCCpcn;3eIgh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFYvQCEQvF2u M1m3dFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4OUKyNlM{Lz5{NkmyNlI{OzxxYU6=
HT-29 M{PJcmFvfGmlYX7j[ZIh[XO|YYm= MnXLOFghcHK| NFHVOZhCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTHQuOjliY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBk\WyuIHfyc5d1cCCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOjVizszNMi=> NYDvUJhURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[5NlIzOzNpPkK2PVIzOjN|PD;hQi=>
HCT116 MkDURY51cWOjbnPldkBie3OjeR?= MX:3NkBpenN? NHjscoZCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4Yh[2WubDDndo94fGhiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ5Lkig{txONg>? NUPJ[IxmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[5NlIzOzNpPkK2PVIzOjN|PD;hQi=>
RKO NFjvdGRCdnSrY3HuZ4VzKGG|c3H5 NID2NZE1QCCqcoO= MWfBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUlvPJINmdGy|IHHzd4V{e2WmIHHzJIlvcGmkaYTpc44hd2ZiY3XscEBoem:5dHigZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IESxMlEh|ryPLh?= MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjl{MkKzN{c,OjZ7MkKyN|M9N2F-
KB MoHYR5l1d3SxeHnjbZR6KGG|c3H5 Mne1O|IhcHK| NE\JT4lEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMSiClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gOE45PCEQvF2u NVnGenl2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkewO|MxPTVpPkK3NFc{ODV3PD;hQi=>
HeLa M1PHXGN6fG:2b4jpZ4l1gSCjc4PhfS=> MVe3NkBpenN? Ml;aR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gOk4zOyEQvF2u MnzaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdyN{OwOVUoRjJ5MEezNFU2RC:jPh?=
MCF7 NE\BPJZEgXSxdH;4bYNqfHliYYPzZZk> MlXMO|IhcHK| MXfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IGPSRkBie3OjeTygTWM2OCB;IE[uOVMh|ryPLh?= MlnRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdyN{OwOVUoRjJ5MEezNFU2RC:jPh?=
HepG2 NWH6OnlJS3m2b4TvfIlkcXS7IHHzd4F6 NY\BcZl2PzJiaILz MlLuR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFYvPiEQvF2u MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzB5M{C1OUc,OjdyN{OwOVU9N2F-
HDF MUDDfZRwfG:6aXPpeJkh[XO|YYm= NH[0SIU4OiCqcoO= M1nyTWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEiGRjDj[YxteyCjZoTldkA4OiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hPy5yMjFOwG0v NXHKNGFwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkewO|MxPTVpPkK3NFc{ODV3PD;hQi=>
143B NETOSoNEgXSxdH;4bYNqfHliYYPzZZk> NIjheXY4OiCqcoO= NVv4[oR2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hOTR|QjDj[YxteyCjZoTldkA4OiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hOTNwMEGg{txONg>? NEHVV2U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{C3N|A2PSd-MkewO|MxPTV:L3G+
thymidine kinase deficient 143B M{HSVmN6fG:2b4jpZ4l1gSCjc4PhfS=> M{HaU|czKGi{cx?= NUDnWVg4S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hfGi7bXnkbY5mKGurbnHz[UBl\W[rY3nlcpQhOTR|QjDj[YxteyCjZoTldkA4OiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hOTZwM{Gg{txONg>? MnqyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdyN{OwOVUoRjJ5MEezNFU2RC:jPh?=
U87MG MVTDfZRwfG:6aXPpeJkh[XO|YYm= NVTrUoU6PzJiaILz NYLve3hNS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hXTh5TVegZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIFnfGW{IEeyJIhzeyCkeTDaNkBkd3WudHXyJINwfW62ZYKgcYV1cG:mLDDJR|UxKD1iMUiuNlUh|ryPLh?= NXTZSJZHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkewPFE4PDJpPkK3NFgyPzR{PD;hQi=>
PC3 M1LpVWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NH24XIc1QCCqcoO= NILifJBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGDDN{Bk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMj63OkDPxE1w MnTGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdyOUK0NVMoRjJ5MEmyOFE{RC:jPh?=
HT-29 MUTBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MkfaOFghcHK| NEPNeopCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjUMVI6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyMlgh|ryPLh?= MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzB7MkSxN{c,OjdyOUK0NVM9N2F-
U87MG NH\vUolCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MUi0PEBpenN? NI\VXJhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGW4O21IKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlY2KM7:TT6= M3zxN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MEmyOFE{Lz5{N{C5NlQyOzxxYU6=
A549 Mnm4RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NXnDNlI2PDhiaILz M1nFbWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz65PEDPxE1w M2jzU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MEmyOFE{Lz5{N{C5NlQyOzxxYU6=
HaCaT NUHwbZRoSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MX20PEBpenN? MmjyRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKYVPhWEBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMU[uNVUh|ryPLh?= MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzB7MkSxN{c,OjdyOUK0NVM9N2F-
MGC803 M1X4ZmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NWTxNVhqPzJiaILz NIq5R4RCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3HR|gxOyClZXzsd{Bie3Onc4Pl[EBieyClZXzsJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxMlI2KM7:TT6= MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzFyNUCyPEc,OjdzMEWwNlg9N2F-
EC109 NXfZZXoxSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MnLmO|IhcHK| MmDKRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCHQ{GwPUBk\WyuczDhd5Nme3OnZDDhd{Bk\WyuIHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|LkG3JO69VS5? M2i4eVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MUC1NFI5Lz5{N{GwOVAzQDxxYU6=
SH-SY5Y NEixU3VCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M1HYcVczKGi{cx?= MUHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOKLWPZOXkh[2WubIOgZZN{\XO|ZXSgZZMh[2WubDDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz6yOkDPxE1w NVfoSFhQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkexNFUxOjhpPkK3NVA2ODJ6PD;hQi=>
U87 NFLNUpJCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M3vFNFczKGi{cx?= M{ftfWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iVUi3JINmdGy|IHHzd4V{e2WmIHHzJINmdGxiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDVwNkGg{txONg>? NXjGRYp3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkexNFUxOjhpPkK3NVA2ODJ6PD;hQi=>
MCF7 MoLJRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MWC3NkBpenN? NYjIcZZ[SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHyg[5Jwf3SqIHnubIljcXSrb36gZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEeuOlEh|ryPLh?= M176RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MUC1NFI5Lz5{N{GwOVAzQDxxYU6=
MDA-MB-231 NFfDemZCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NVHzbW85PDhiaILz M32wSmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTJ|MTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOjRwNjFOwG0v M3jtOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MUK4NVgxLz5{N{GyPFE5ODxxYU6=
MCF7 NXXFSXlxSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MorkOFghcHK| NITlWm1CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlch[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOwMlQyKM7:TT6= Mn7iQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdzMkixPFAoRjJ5MUK4NVgxRC:jPh?=
A549 M3vKbGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 Ml\xOFghcHK| MULBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEF3NEmgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN3LkSxJO69VS5? NVHSTmpSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkexNlgyQDBpPkK3NVI5OThyPD;hQi=>
HepG2 NHXoV4ZCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NH3JSJQ1QCCqcoO= MWPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEincFeyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB2Nj64N{DPxE1w Ml;DQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdzMkixPFAoRjJ5MUK4NVgxRC:jPh?=
MCF7 NH64fGtEgXSxdH;4bYNqfHliYYPzZZk> NX\Oe|BHPDhiaILz NXjabphxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTNwNTFOwG0v MnrwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdzM{O1PVMoRjJ5MUOzOVk{RC:jPh?=
Bcap37 NGizSFhEgXSxdH;4bYNqfHliYYPzZZk> NW\GSGxvPDhiaILz Moi2R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRoNieDN5IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPS52NzFOwG0v NGrLcGE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{GzN|U6Oyd-MkexN|M2QTN:L3G+
Hep3B MXXDfZRwfG:6aXPpeJkh[XO|YYm= NUSxb5RYPDhiaILz M4n4UGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeDOEIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPy53MzFOwG0v Mme2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdzM{O1PVMoRjJ5MUOzOVk{RC:jPh?=
A549 NYfTOXZyS3m2b4TvfIlkcXS7IHHzd4F6 MUS0PEBpenN? Mm\rR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlEvPThizszNMi=> M36yVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MUOzOVk{Lz5{N{GzN|U6OzxxYU6=
U251 NFfPO|ZEgXSxdH;4bYNqfHliYYPzZZk> NF73UFg1QCCqcoO= M{LOUGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHUzPTFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI1NjZ7IN88UU4> M33rRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MUOzOVk{Lz5{N{GzN|U6OzxxYU6=
HepG2 M1rTcGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWnobFB2PDhiaILz M4HM[2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzPS5zNzFOwG0v NHXFWnE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{GzN|U6Oyd-MkexN|M2QTN:L3G+
LNCAP NFfqbVhEgXSxdH;4bYNqfHliYYPzZZk> MkfSNlQhcHK| Ml7TR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUG5ESVBiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhOjRiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGlEPTBiPTCwMlA{KM7:TT6= MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzF3Nke3NEc,OjdzNU[3O|A9N2F-
PC3 MV3DfZRwfG:6aXPpeJkh[XO|YYm= MomwNlQhcHK| MX;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZZN{\XO|ZXSgZZMh\3Kxd4ToJIlvcGmkaYTpc44h[W[2ZYKgNlQhcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFnDOVAhRSByLkCzJO69VS5? NFS5[2w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{G1Olc4OCd-MkexOVY4PzB:L3G+
Bcap37 MV3DfZRwfG:6aXPpeJkh[XO|YYm= MoPmOFghcHK| NVzEVJdsS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSmOjcEO3JINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC1MlE5KM7:TT6= NF[0XWg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{G4PVY4Pid-MkexPFk3PzZ:L3G+
MCF7 MoPnR5l1d3SxeHnjbZR6KGG|c3H5 M3PsfFQ5KGi{cx?= NEKxSpBEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMT61JO69VS5? M3q3d|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MUi5Olc3Lz5{N{G4PVY4PjxxYU6=
Hep3B NX3XRVYxS3m2b4TvfIlkcXS7IHHzd4F6 NHzSOZg1QCCqcoO= NXjB[ZR[S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyM1KgZ4VtdHNiYYPz[ZN{\WRiYYOg[5Jwf3SqIHnubIljcXSrb36gZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKyMlk6KM7:TT6= MmXXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdzOEm2O|YoRjJ5MUi5Olc3RC:jPh?=
HepG2 NFm1bpdEgXSxdH;4bYNqfHliYYPzZZk> NEXvO|Q1QCCqcoO= NVrEU5lQS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYYPz[ZN{\WRiYYOg[5Jwf3SqIHnubIljcXSrb36gZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IESwMlM1KM7:TT6= MlfSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdzOEm2O|YoRjJ5MUi5Olc3RC:jPh?=
A549 NHPYWJREgXSxdH;4bYNqfHliYYPzZZk> MYW0PEBpenN? MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9vKGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1PC5yNTFOwG0v M4TpcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MUi5Olc3Lz5{N{G4PVY4PjxxYU6=
PA1 MWfDfZRwfG:6aXPpeJkh[XO|YYm= NIqzVY01QCCqcoO= NIPRWFVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSTFiY3XscJMh[XO|ZYPz[YQh[XNiZHXjdoVie2ViaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDhwNUGg{txONg>? MmjzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd{MUC0N|goRjJ5MkGwOFM5RC:jPh?=
U87MG M2D5dWN6fG:2b4jpZ4l1gSCjc4PhfS=> NEPITm81QCCqcoO= NIryWm9EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBWQDePRzDj[YxteyCjc4Pld5Nm\CCjczDk[YNz\WG|ZTDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUWuOFgh|ryPLh?= NF;HUW89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{KxNFQ{QCd-MkeyNVA1Ozh:L3G+
MCF7 MUPDfZRwfG:6aXPpeJkh[XO|YYm= NUHHZW8yPDhiaILz M1nBcWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[XO|ZYPz[YQh[XNiZHXjdoVie2ViaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN{LkK3JO69VS5? NVfqV2pPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkeyNVA1OzhpPkK3NlExPDN6PD;hQi=>
LNCAP NWrielhYS3m2b4TvfIlkcXS7IHHzd4F6 NWXiUVhHPDhiaILz NHTuVYNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBNVkODUDDj[YxteyCjc4Pld5Nm\CCjczDk[YNz\WG|ZTDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNEeuNVgh|ryPLh?= NWHmSlFTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkeyNVA1OzhpPkK3NlExPDN6PD;hQi=>
MCF7 MUfDfZRwfG:6aXPpeJkh[XO|YYm= M3vOb|I1KGi{cx?= MlvyR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJN2en[rdnHibYxqfHliYX\0[ZIhOjRiaILzJIJ6KGO{eYP0ZYwhfmmxbHX0JJN1[WmwaX7nJIJie2WmIH3pZ5Jwe2OxcHnjJIFv[Wy7c3nzMEBKSzVyIE2gNVEvOSEQvF2u NGXQfY89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{KzOFg6Oyd-MkeyN|Q5QTN:L3G+
HepG2 Mn;MRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MYi0PEBpenN? M3T3fGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXwS|Ih[2WubIOgcYVie3W{ZXSgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IES2Mlg{KM7:TT6= NFmzeGY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{K4O|M3QCd-MkeyPFc{Pjh:L3G+
A375-S2 MkfJRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NYrObFIzPDhiaILz MV3BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEF|N{WtV|Ih[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIILl[JVkfGmxbjDhd5NigSxiSVO1NEA:KDFwOUGg{txONg>? M{HSXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5Mkm1OVA3Lz5{N{K5OVUxPjxxYU6=
ACHN MUTBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NEDIbFY1QCCqcoO= NGrZdWNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFHDTG4h[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIILl[JVkfGmxbjDhd5NigSxiSVO1NEA:KDJwN{Og{txONg>? MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzJ7NUWwOkc,Ojd{OUW1NFY9N2F-
22Rv1 MoXCRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MmDHOFghcHK| NVfhNmR7SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjCyNnJ3OSClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgdoVlfWO2aX;uJIF{e2G7LDDJR|UxKD1iMz64N{DPxE1w NWntdZFKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkeyPVU2ODZpPkK3Nlk2PTB4PD;hQi=>
C4-2B NWn6[pVHSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MV[0PEBpenN? MlPqRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCFND2yRkBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIHPlcIwhfmmjYnnsbZR6KGGodHXyJFQ5KGi{czDifUBOXFRicnXkeYN1cW:wIHHzd4F6NCCLQ{WwJF0hPS54NDFOwG0v NXfjelA4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkeyPVU2ODZpPkK3Nlk2PTB4PD;hQi=>
A498 NVf2dlhjSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MmPMOFghcHK| NFr1[YhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG0PVgh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIILl[JVkfGmxbjDhd5NigSxiSVO1NEA:KDhwOEOg{txONg>? MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzJ7NUWwOkc,Ojd{OUW1NFY9N2F-
A549 MXvBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MWS3NkBpenN? NGL2WIFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwIHPlcIwhfmmjYnnsbZR6KGGodHXyJFczKGi{czDifUBYW1RvODDhd5NigSxiSVO1NEA:KDJwODFOwG0v NF;zWpc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{OxNVg6PSd-MkezNVE5QTV:L3G+
MDA-MB-231 MWrBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MlLrO|IhcHK| NEThOnJCdnSrcILvcIln\XKjdHnvckBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi1{M{GgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIFnfGW{IEeyJIhzeyCkeTDXV3QuQCCjc4PhfUwhUUN3MDC9JFUvOiEQvF2u MoDEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd|MUG4PVUoRjJ5M{GxPFk2RC:jPh?=
HeLa NILMZlVCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MlX5O|IhcHK| NH3FSFVCdnSrcILvcIln\XKjdHnvckBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwIHPlcIwhfmmjYnnsbZR6KGGodHXyJFczKGi{czDifUBYW1RvODDhd5NigSxiSVO1NEA:KDVwODFOwG0v M2\qWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5M{GxPFk2Lz5{N{OxNVg6PTxxYU6=
MCF7 NET5SY9EgXSxdH;4bYNqfHliYYPzZZk> M1TiWFQ5KGi{cx?= MYLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOyEQvF2u NXLzRWpTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkezOFM5PTNpPkK3N|Q{QDV|PD;hQi=>
WI38 NYXVNHA5S3m2b4TvfIlkcXS7IHHzd4F6 MnPiOFghcHK| NHqxNIlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBYUTN6IHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNDFOwG0v M4rCS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5M{SzPFU{Lz5{N{O0N|g2OzxxYU6=
HepG2 NULDd4xjS3m2b4TvfIlkcXS7IHHzd4F6 MVq0PEBpenN? M3HSfGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iODFOwG0v NXu2O5E2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkezOFM5PTNpPkK3N|Q{QDV|PD;hQi=>
UO31 MVzDfZRwfG:6aXPpeJkh[XO|YYm= M4\3R|Q5KGi{cx?= M{C2T2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHVQOzFiY3XscJMhdWWjc4Xy[YQh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFYvPzZyOEOg{txONg>? MoS5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd|OUGxN|UoRjJ5M{mxNVM2RC:jPh?=
U251 NHTxeoREgXSxdH;4bYNqfHliYYPzZZk> NVLlbXNwPDhiaILz MnrlR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gWVI2OSClZXzsd{Bu\WG|dYLl[EBi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBIUTVyIE2gOFIvPjV5OTFOwG0v NWfCbVc6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkezPVEyOzVpPkK3N|kyOTN3PD;hQi=>
HCT116 M4LiWGN6fG:2b4jpZ4l1gSCjc4PhfS=> MlnnOFghcHK| NWC0SWtTS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHzd4V{e2WmIHHzJINmdGxiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF3LkO4JO69VS5? NFHjTW49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{S0PFc4PCd-Mke0OFg4PzR:L3G+
MDA-MB-231 Ml3TR5l1d3SxeHnjbZR6KGG|c3H5 NYn3V4Y{PDhiaILz MljrR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDhd5Nme3OnZDDhd{Bk\WyuIHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|NT65NUDPxE1w M{e5fVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NES4O|c1Lz5{N{S0PFc4PDxxYU6=
A549 NEnNdHlEgXSxdH;4bYNqfHliYYPzZZk> MUC0PEBpenN? NELtd2FEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGG|c3Xzd4VlKGG|IHPlcIwh\3Kxd4ToJIlvcGmkaYTpc44h[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFM6Njh4IN88UU4> NUOxd2VTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke0OFg4PzRpPkK3OFQ5Pzd2PD;hQi=>
Caco2 NXSxZVk5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUW3NkBpenN? NFr2c4JIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBE[WOxMjDj[YxteyCvZXHzeZJm\CCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCJSUWwJF0hOy5|IN88UU4> MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzVyNEWzO{c,Ojd3MES1N|c9N2F-
MCF7 NVPLO|JVT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWK0elRzPzJiaILz MnnwS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUWNHPyClZXzsd{Bu\WG|dYLl[EBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBIUTVyIE2gN{43KM7:TT6= M3XBblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NUC0OVM4Lz5{N{WwOFU{PzxxYU6=
PC3 MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml3OO|IhcHK| NGjPTplIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBRSzNiY3XscJMhdWWjc4Xy[YQh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhT0l3MDC9JFQvOSEQvF2u MnHrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd3MES1N|coRjJ5NUC0OVM4RC:jPh?=
A549 MYPDfZRwfG:6aXPpeJkh[XO|YYm= NVnQ[md4PzJiaILz MUXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJI1m[XO3cnXkJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC2Mlgh|ryPLh?= NWnDcG1WRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke1N|c6OjRpPkK3OVM4QTJ2PD;hQi=>
SGC7901 NFjUSI5EgXSxdH;4bYNqfHliYYPzZZk> NHjyWYw4OiCqcoO= MX\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTS2M4QTBzIHPlcIx{KG2nYYP1doVlKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOS57IN88UU4> NEjBTHE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{WzO|kzPCd-Mke1N|c6OjR:L3G+
MDA-MB-435S NXTKXHZUS3m2b4TvfIlkcXS7IHHzd4F6 M3HRWVczKGi{cx?= M1jweWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj20N|VUKGOnbHzzJI1m[XO3cnXkJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOU4zKM7:TT6= NFvHVnA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{WzO|kzPCd-Mke1N|c6OjR:L3G+
PC3 MULDfZRwfG:6aXPpeJkh[XO|YYm= NFeyRno4OiCqcoO= MnnxR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJI1m[XO3cnXkJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0Nk42KM7:TT6= MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzV|N{myOEc,Ojd3M{e5NlQ9N2F-
colon cancer cell MmDlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVPXTVVvPDhiaILz NEGwWWlIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBkd2yxbjDjZY5k\XJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFgvPCEQvF2u MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzV3NES0OEc,Ojd3NUS0OFQ9N2F-
leukemia cell NHjPVY5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWO0PEBpenN? MlTDS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gcIV2c2WvaXGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiR1m1NEA:KDF3LkGg{txONg>? NYP5cXBpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke1OVQ1PDRpPkK3OVU1PDR2PD;hQi=>
prostate cancer cell MnrlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWi0PEBpenN? NIXqb5ZIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBxem:|dHH0[UBk[W6lZYKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiR1m1NEA:KDJ{Lkeg{txONg>? NIjFNJU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{W1OFQ1PCd-Mke1OVQ1PDR:L3G+
renal cancer cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2DVcFQ5KGi{cx?= M{HvXWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJJJmdmGuIHPhcoNmeiClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBIUTVyIE2gOFUvPiEQvF2u MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzV3NES0OEc,Ojd3NUS0OFQ9N2F-
DU145 Ml[xR5l1d3SxeHnjbZR6KGG|c3H5 MlLtOFghcHK| MmjkR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSHUyPDViY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{Nj6xJO69VS5? MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzV4MUexPEc,Ojd3NkG3NVg9N2F-
HeLa MVTDfZRwfG:6aXPpeJkh[XO|YYm= NGH0U2c1QCCqcoO= Ml35R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ6LkKg{txONg>? MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzV4MUexPEc,Ojd3NkG3NVg9N2F-
IOSE-144 NY[xenMxS3m2b4TvfIlkcXS7IHHzd4F6 MmLHOFghcHK| M3f1S2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGlQW0VvMUS0JINmdGy|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|YvOSEQvF2u M1:zVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NU[xO|E5Lz5{N{W2NVcyQDxxYU6=
HepG2 Moq1R5l1d3SxeHnjbZR6KGG|c3H5 NGK3[45EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKGe{b4f0bEBqdmirYnn0bY9vKGK7IF3UWEBie3OjeTygTWM2OCB;IEGuN{DPxE1w MnW4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd3NkG3NVkoRjJ5NU[xO|E6RC:jPh?=
DU145 MmHwR5l1d3SxeHnjbZR6KGG|c3H5 MUjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDEWVE1PSClZXzsd{Bie3Onc4Pl[EBieyClZXzsJIdzd3e2aDDpcohq[mm2aX;uJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFwNjFOwG0v NWq2XXVpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke1OlE4OTlpPkK3OVYyPzF7PD;hQi=>
MDA-MB-231 NHvhXndEgXSxdH;4bYNqfHliYYPzZZk> NFLXUpZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOTEFvTVKtNlMyKGOnbHzzJIF{e2W|c3XkJIF{KGOnbHyg[5Jwf3SqIHnubIljcXSrb36gZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOS56IN88UU4> M2rhNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NU[xO|E6Lz5{N{W2NVcyQTxxYU6=
HeLa NF3QemREgXSxdH;4bYNqfHliYYPzZZk> Mm\jR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bie3Onc4Pl[EBieyClZXzsJIdzd3e2aDDpcohq[mm2aX;uJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFwOTFOwG0v NUXsZXp{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke1OlE4OTlpPkK3OVYyPzF7PD;hQi=>
SW780 NEDZdI5EgXSxdH;4bYNqfHliYYPzZZk> NWrGO4x5PzJiaILz M4XWN2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNYPzhyIHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDd{IHjyd{BjgSCFQ1u4JIF{e2G7LDDJR|UxKD1iNj65PUDPxE1w Ml30QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd3OUe0NVEoRjJ5NUm3OFEyRC:jPh?=
MGC803 MoD1R5l1d3SxeHnjbZR6KGG|c3H5 NF\UUYY4OiCqcoO= NVz3WoxIS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUeFOECzJINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IEeyJIhzeyCkeTDDR2s5KGG|c3H5MEBKSzVyIE2gNVAvPjRizszNMi=> MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzV7N{SxNUc,Ojd3OUe0NVE9N2F-
HL-7702 NFO1eWxEgXSxdH;4bYNqfHliYYPzZZk> NF\0[Ic4OiCqcoO= MnjXR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGwuPzdyMjDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nliQ1PLPEBie3OjeTygTWM2OCB;IEGyMlg2KM7:TT6= M4m5NFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NUm3OFEyLz5{N{W5O|QyOTxxYU6=
MCF7 M4TyeGN6fG:2b4jpZ4l1gSCjc4PhfS=> NYXuVm9CPzJiaILz NUTqUWw{S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nliQ1PLPEBie3OjeTygTWM2OCB;IEGzMlE6KM7:TT6= MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzV7N{SxNUc,Ojd3OUe0NVE9N2F-
GES-1 M{WxcGN6fG:2b4jpZ4l1gSCjc4PhfS=> M4CxdFczKGi{cx?= NXzvSIlnS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hT0WVLUGgZ4VtdHNiYYPz[ZN{\WRiYYOg[5Jwf3SqIHnubIljcXSrb36gZYZ1\XJiN{KgbJJ{KGK7IFPDT|gh[XO|YYmsJGlEPTBiPTCxN{44PSEQvF2u NXzRPHNPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke1PVc1OTFpPkK3OVk4PDFzPD;hQi=>
TE1 MV3DfZRwfG:6aXPpeJkh[XO|YYm= NVnuXpdkPzJiaILz M17xO2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHRGOSClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkA4OiCqcoOgZpkhS0ONODDhd5NigSxiSVO1NEA:KDF5LkOyJO69VS5? M3izW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NUm3OFEyLz5{N{W5O|QyOTxxYU6=
A549 MlfyR5l1d3SxeHnjbZR6KGG|c3H5 M3HOOVQ5KGi{cx?= M1zDdmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[XO|ZYPz[YQh[XNiY3XscEBoem:5dHigbY5pcWKrdHnvckBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|AvPDdizszNMi=> NFX3ZYw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{[xOFQxQCd-Mke2NVQ1ODh:L3G+
MDA-MB-231 M4\XT2N6fG:2b4jpZ4l1gSCjc4PhfS=> MUS0PEBpenN? NV\zR|ZXS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUSDLV3CMVI{OSClZXzsd{Bie3Onc4Pl[EBieyClZXzsJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzOU46QCEQvF2u MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzZzNESwPEc,Ojd4MUS0NFg9N2F-
DU145 NUSyV3JUS3m2b4TvfIlkcXS7IHHzd4F6 NV:2TJJ7PDhiaILz MULDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDEWVE1PSClZXzsd{Bie3Onc4Pl[EBieyClZXzsJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0NE42QCEQvF2u MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzZzNESwPEc,Ojd4MUS0NFg9N2F-
PC3 MkfnR5l1d3SxeHnjbZR6KGG|c3H5 M4T0PFQ5KGi{cx?= MnXmR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHyg[5Jwf3SqIHnubIljcXSrb36gZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IES1MlMzKM7:TT6= M3\xe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NkG0OFA5Lz5{N{[xOFQxQDxxYU6=
MCF7 M1v4[2N6fG:2b4jpZ4l1gSCjc4PhfS=> MX60PEBpenN? M3KyRWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25ibXXhd5Vz\WRiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiR1m1NEA:KDRwNTFOwG0v NITW[5E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{[4PFE5PCd-Mke2PFgyQDR:L3G+
HepG2 MWHGeY5kfGmxbjDhd5NigQ>? M12xOFQ5KGi{cx?= M{S3RWhmeGG2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYYPz[ZN{\WRiYYOg[5Jwf3SqIHnubIljcXSrb36gcYVie3W{ZXSgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygS2k2OCB;IEeg{txONg>? NX3NOXFDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke2PFgyQDRpPkK3Olg5OTh2PD;hQi=>
U87 NWTMbJZiTnWwY4Tpc44h[XO|YYm= MXu0PEBpenN? NH7jbJdP\XW{b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hXTh5IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIH3lZZN2emWmIHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFfJOVAhRSBzMzFOwG0v M3LhWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5Nki4NVg1Lz5{N{[4PFE5PDxxYU6=
HCT116 NHnZV4VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF;KeIs4OiCqcoO= NFvLfIZIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBJS1RzMU[gZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WUzDhd5NigSxiSVO1NEA:KDJwNTFOwG0v M1;afFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{C0PFEyLz5{N{ewOFgyOTxxYU6=
HeLa NUHFSpVKS3m2b4TvfIlkcXS7IHHzd4F6 NV60cGFtS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKGe{b4f0bEBqdmirYnn0bY9vKGK7IF3UWEBie3OjeTygTWM2OCB;IEGuOkDPxE1w NHnpTVA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{eyNFI6Pid-Mke3NlAzQTZ:L3G+
PC3 MVXDfZRwfG:6aXPpeJkh[XO|YYm= MlHvR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHyg[5Jwf3SqIHnubIljcXSrb36gZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOS56IN88UU4> NX32V4poRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3NlAzQTZpPkK3O|IxOjl4PD;hQi=>
HepG2 MXzDfZRwfG:6aXPpeJkh[XO|YYm= MYTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bie3Onc4Pl[EBieyClZXzsJIdzd3e2aDDpcohq[mm2aX;uJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFwODFOwG0v NFLSe2c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{eyNFI6Pid-Mke3NlAzQTZ:L3G+
MDA-MB-231 NEG0SJBEgXSxdH;4bYNqfHliYYPzZZk> M4H6UWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj2yN|Eh[2WubIOgZZN{\XO|ZXSgZZMh[2WubDDndo94fGhiaX7obYJqfGmxbjDifUBOXFRiYYPzZZktKEmFNUCgQUAyNjlizszNMi=> MnHHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd5MkCyPVYoRjJ5N{KwNlk3RC:jPh?=
L1210 MVrBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M3vDTFQ5KGi{cx?= MmPBRY51cS2ycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViTEGyNVAh[2WubIOgcYVie3W{ZXSgZYZ1\XJiNEigbJJ{KGK7IHPveYx1\XJiY3;1cpRmeiCvZYToc4QtKEmFNUCgQUAxNjN|IN88UU4> NYnvd2xFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3OVAyPTRpPkK3O|UxOTV2PD;hQi=>
HeLa M2TGfWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M4PtbVQh\GG7cx?= NY\jTYJxSW62aT3wdo9tcW[ncnH0bZZmKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bu\WG|dYLl[EBi\nSncjC0JIRigXNiYomgZ492dHSncjDjc5VvfGW{IH3leIhw\CxiSVO1NEA:KDBwNUSg{txONg>? MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzd3MEG1OEc,Ojd5NUCxOVQ9N2F-
CEM MXjBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M{H6UlczKGi{cx?= M2DhXWFvfGlvcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFPFUUBk\WyuczDt[YF{fXKnZDDh[pRmeiB5MjDodpMh[nliY3;1cJRmeiClb4XueIVzKG2ndHjv[EwhUUN3MDC9JFE5KM7:TT6= NXzMVYNVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3OVAyPTRpPkK3O|UxOTV2PD;hQi=>
PC9 NHPMS4dEgXSxdH;4bYNqfHliYYPzZZk> MknCR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM6KGOnbHzzJIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9vKGK7IF3UWEBie3OjeTygTWM2OCB;IEGuPVkh|ryPLh?= NV\kTHF6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3OlkxOzRpPkK3O|Y6ODN2PD;hQi=>
MGC803 NGe3e4JEgXSxdH;4bYNqfHliYYPzZZk> NUPXNW9qS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUeFOECzJINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFyLkG0JO69VS5? Mn3QQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd5NkmwN|QoRjJ5N{[5NFM1RC:jPh?=
A549 Mn3ER5l1d3SxeHnjbZR6KGG|c3H5 NXLSeHpwS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDifUBOXFRiYYPzZZktKEmFNUCgQUAyOy57NTFOwG0v M4e2TlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{[5NFM1Lz5{N{e2PVA{PDxxYU6=
EC109 NU[4ZXo6S3m2b4TvfIlkcXS7IHHzd4F6 MkDwR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSWMyODliY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYomgUXRVKGG|c3H5MEBKSzVyIE2gNlUvQTlizszNMi=> M3zyclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{[5NFM1Lz5{N{e2PVA{PDxxYU6=
MGC803 MV\BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MneyO|IhcHK| M3Ta[WFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVfDPFA{KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC3MlM2KM7:TT6= NX7z[GoxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3O|E2QTlpPkK3O|cyPTl7PD;hQi=>
MCF7 NUPufXNUSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NG\wd|I4OiCqcoO= MoXMRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB7LkK1JO69VS5? NEHzeIE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{e3NVU6QSd-Mke3O|E2QTl:L3G+
EC109 MnHnRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NHjp[FM4OiCqcoO= NUP3bHEzSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDFR|ExQSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVAvPTlizszNMi=> NVS2T4prRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3O|E2QTlpPkK3O|cyPTl7PD;hQi=>
HUCCA MXLDfZRwfG:6aXPpeJkh[XO|YYm= NIXncoYzPCCqcoO= MXTDfZRwfG:6aXPpeJkh[WejaX7zeEBJXUOFQTDj[YxteyCjc4Pld5Nm\CCjczDk[YNz\WG|ZTDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB{NDDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUOuOEDPxE1w MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzh{NUe2N{c,Ojd6MkW3OlM9N2F-
QBC939 MmTDR5l1d3SxeHnjbZR6KGG|c3H5 NF;DSFkzPCCqcoO= NV25[GFsS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWUKFOUO5JINmdGy|IHHzd4V{e2WmIHHzJIRm[3KnYYPlJIlvKGOnbHygeoli[mmuaYT5JIFnfGW{IEK0JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOk4yKM7:TT6= NXLwcYQ{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke4NlU4PjNpPkK3PFI2PzZ|PD;hQi=>
SW620 M1nuOmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MYm3NkBpenN? MlLrRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVV{[yNEBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD6wPEDPxE1w MnzYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd6N{W3O|koRjJ5OEe1O|c6RC:jPh?=
CFPAC-1 NUDUbHJ7SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MUi3NkBpenN? Mnj5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCFRmDBR{0yKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlE1KM7:TT6= MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzh5NUe3PUc,Ojd6N{W3O|k9N2F-
WI38 M3ryU2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NVTrZmdkPzJiaILz NXi1TmNLSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDXTVM5KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlk1KM7:TT6= MlS1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd6N{W3O|koRjJ5OEe1O|c6RC:jPh?=
A549 MojURY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M1HMVFczKGi{cx?= Mk\QRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDNUS5JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{Lkig{txONg>? M1zrd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5OEe1O|c6Lz5{N{i3OVc4QTxxYU6=
HeLa MmnvRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MUW3NkBpenN? M1fSTGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iOD64NUDPxE1w NGDafXI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{i3OVc4QSd-Mke4O|U4Pzl:L3G+
HepG2 MWHBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MmrMO|IhcHK| NEXiUYpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC4Mlkh|ryPLh?= NGjBeoQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{i3OVc4QSd-Mke4O|U4Pzl:L3G+
Hep3B MnjKR5l1d3SxeHnjbZR6KGG|c3H5 NVPYd2FLS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyM1KgZ4VtdHNiYYPz[ZN{\WRiYYOgZ4VtdCCpcn;3eIghcW6qaXLpeIlwdiCkeTDNWHQh[XO|YYmsJGlEPTBiPTC5MlM3KM7:TT6= M4nRVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5OUGzNVc6Lz5{N{mxN|E4QTxxYU6=
A549 NXfhNJZ{S3m2b4TvfIlkcXS7IHHzd4F6 MY\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHyg[5Jwf3SqIHnubIljcXSrb36gZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTZwNkOg{txONg>? NGPGNHE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{mxN|E4QSd-Mke5NVMyPzl:L3G+
WISH MYjDfZRwfG:6aXPpeJkh[XO|YYm= MWGyOEBpenN? NVjPPIlPS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hX0mVSDDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZYZ1\XJiMkSgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEeuNUDPxE1w M3fEd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5OUWxOFg4Lz5{N{m1NVQ5PzxxYU6=
WI38 MlT4R5l1d3SxeHnjbZR6KGG|c3H5 MYSyOEBpenN? M3TRdWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHdKOzhiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDJ2IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB7LkOg{txONg>? M1TUN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5OUWxOFg4Lz5{N{m1NVQ5PzxxYU6=
A549 NGnzcmVCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M1LRUVczKGi{cx?= M4WxZ2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMT6xOkDPxE1w M{DEflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5OUi3OFg2Lz5{N{m4O|Q5PTxxYU6=
MDA-MB-231 M1nmXmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MoDGO|IhcHK| MUPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2GQT3NRk0zOzFiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFUh|ryPLh?= MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzl6N{S4OUc,Ojd7OEe0PFU9N2F-
HepG2 NED4d4hCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NH\SbWo4OiCqcoO= NIHzO|dCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC1JO69VS5? NXn3XmN6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke5PFc1QDVpPkK3PVg4PDh3PD;hQi=>
MCF7 Ml:zRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MXu3NkBpenN? NVfle3h{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC3MlEzKM7:TT6= MnTLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd7OEe0PFUoRjJ5OUi3OFg2RC:jPh?=
Hep3B MU\DfZRwfG:6aXPpeJkh[XO|YYm= NXzkZ4JkPDhiaILz NVjEZ3NlS3m2b4TvfIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTIVxO0JiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFyLkWzJO69VS5? M1[zN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5OUmzOVE3Lz5{N{m5N|UyPjxxYU6=
HepG2 NFfHOXREgXSxdH;4bYNqfHliYYPzZZk> MWi0PEBpenN? NGLtUXFEgXSxdH;4bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOzJwNjFOwG0v MnXIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd7OUO1NVYoRjJ5OUmzOVE3RC:jPh?=
HepG2 M4Po[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{S0fVI1KGi{cx?= M1fjRmdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{Oi56NzFOwG0v MnHDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjhyMUGyNlAoRjJ6MEGxNlIxRC:jPh?=
PA1 NIDMdpRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4DIelI1KGi{cx?= NVnlTXhuT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hWEFzIHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{QS53IN88UU4> Ml\UQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjhyMUGyNlAoRjJ6MEGxNlIxRC:jPh?=
HCT15 MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoO2NlQhcHK| M3f1OGdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGhEXDF3IHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1PS5yMTFOwG0v MnnrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjhyMUGyNlAoRjJ6MEGxNlIxRC:jPh?=
PC3 NGLkZ4hEgXSxdH;4bYNqfHliYYPzZZk> NY\jUGRqPzJiaILz NIC1UnpEgXSxdH;4bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwIHPlcIwhfmmjYnnsbZR6KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAyPS5|MTFOwG0v MmXyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjhyMUGyNlMoRjJ6MEGxNlI{RC:jPh?=
SKOV3 NWS0XGxzS3m2b4TvfIlkcXS7IHHzd4F6 MUe3NkBpenN? MX7DfZRwfG:6aXOgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVS1;WN{Bk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJkh[W[2ZYKgO|IhcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFI{NjFzIN88UU4> M1TjZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MEGxNlI{Lz5{OECxNVIzOzxxYU6=
A549 MXnDfZRwfG:6aXPpeJkh[XO|YYm= NVjvOVVsPzJiaILz NH:1d|NEgXSxdH;4bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA4OiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hOzJwMUWg{txONg>? MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDBzMUKyN{c,OjhyMUGyNlM9N2F-
HepG2 MYPDfZRwfG:6aXPpeJkh[XO|YYm= NF7CXWI1QCCqcoO= NUj3O41iS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYYPz[ZN{\WRiYYOg[IVkemWjc3WgbY4h[2WubDDwdo9tcW[ncnH0bY9vKGGodHXyJFQ5KGi{czDifUBOXFRiY3;sc5JqdWW2cnnjJIF{e2G7LDDJR|UxKD1iMUCuNVch|ryPLh?= NIXrT5Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OECzPFMzPyd-MkiwN|g{Ojd:L3G+
Hep3B NVrDXZlYS3m2b4TvfIlkcXS7IHHzd4F6 NFXvS|A1QCCqcoO= NYDhcoRvS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyM1KgZ4VtdHNiYYPz[ZN{\WRiYYOg[IVkemWjc3WgbY4h[2WubDDwdo9tcW[ncnH0bY9vKGGodHXyJFQ5KGi{czDifUBOXFRiY3;sc5JqdWW2cnnjJIF{e2G7LDDJR|UxKD1iMUCuOVMh|ryPLh?= M1nWSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MEO4N|I4Lz5{OECzPFMzPzxxYU6=
A549 MmnVR5l1d3SxeHnjbZR6KGG|c3H5 MYe0PEBpenN? M2nBN2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[XO|ZYPz[YQh[XNiZHXjdoVie2ViaX6gZ4VtdCCycn;sbYZmemG2aX;uJIFnfGW{IES4JIhzeyCkeTDNWHQh[2:ub4LpcYV1emmlIHHzd4F6NCCLQ{WwJF0hOzRwMkeg{txONg>? NXzCRY41RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkiwN|g{OjdpPkK4NFM5OzJ5PD;hQi=>
MCF7 NWqxb5lIS3m2b4TvfIlkcXS7IHHzd4F6 NYfGVmxbPDhiaILz MnnRR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bie3Onc4Pl[EBieyCmZXPy[YF{\SCrbjDj[YxtKHC{b3zp[oVz[XSrb36gZYZ1\XJiNEigbJJ{KGK7IF3UWEBkd2yxcnnt[ZRzcWNiYYPzZZktKEmFNUCgQUA1Oi55ODFOwG0v MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDB|OEOyO{c,OjhyM{izNlc9N2F-
Bcap37 NVLQVJlmS3m2b4TvfIlkcXS7IHHzd4F6 MoO2OFghcHK| MnO5R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRoNieDN5IHPlcIx{KGG|c3Xzd4VlKGG|IHTlZ5Jm[XOnIHnuJINmdGxicILvcIln\XKjdHnvckBi\nSncjC0PEBpenNiYomgUXRVKGOxbH;ybY1mfHKrYzDhd5NigSxiSVO1NEA:KDR5LkGg{txONg>? MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDB|OEOyO{c,OjhyM{izNlc9N2F-
U251 M161cmN6fG:2b4jpZ4l1gSCjc4PhfS=> MonsOFghcHK| NHSzTWpEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBWOjVzIHPlcIx{KGG|c3Xzd4VlKGG|IHTlZ5Jm[XOnIHnuJINmdGxicILvcIln\XKjdHnvckBi\nSncjC0PEBpenNiYomgUXRVKGOxbH;ybY1mfHKrYzDhd5NigSxiSVO1NEA:KDR6Lk[4JO69VS5? MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDB|OEOyO{c,OjhyM{izNlc9N2F-
MGC803 M4fKSGN6fG:2b4jpZ4l1gSCjc4PhfS=> NHrtVIM1QCCqcoO= NEnZWmVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOT0N6MEOgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gO{4zOSEQvF2u NFL2XFc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OECzPFMzQSd-MkiwN|g{Ojl:L3G+
EC109 NETrV2NEgXSxdH;4bYNqfHliYYPzZZk> M1G3W|Q5KGi{cx?= MWXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDFR|ExQSClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMD6zJO69VS5? M4DNN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MEO4N|I6Lz5{OECzPFMzQTxxYU6=
PC3 MoXMR5l1d3SxeHnjbZR6KGG|c3H5 MmTVOFghcHK| M2TFc2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHBEOyClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{OT6zNUDPxE1w NH3kcFM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OECzPFMzQSd-MkiwN|g{Ojl:L3G+
A549 MkjrRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NIrhWok1QCCqcoO= MUfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEF3NEmgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFyLkWg{txONg>? M4PJelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MEezOlc3Lz5{OEC3N|Y4PjxxYU6=
MCF7 M1K0WGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MnPuOFghcHK| MWrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF7LkKg{txONg>? NInHPFM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEC3N|Y4Pid-MkiwO|M3PzZ:L3G+
HCT116 NHX0bVdCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MVG0PEBpenN? M2T3fWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPUNVE3KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyPU4zKM7:TT6= MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDB5M{[3Okc,OjhyN{O2O|Y9N2F-
BGC823 Ml[zRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M{HTOlQ5KGi{cx?= M4jpR2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQlfDPFI{KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzOE45KM7:TT6= NIjQZ4c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEC3N|Y4Pid-MkiwO|M3PzZ:L3G+
IOSE-144 M4DhfWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NWPJ[4R{PDhiaILz MnuwRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCLT2PFMVE1PCClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|gvOSEQvF2u NH71TYM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEC3N|Y4Pid-MkiwO|M3PzZ:L3G+
MCF7 MVLBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? Mmi3OFghcHK| MVHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ4LkG0JO69VS5? MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDFzMEi3NUc,OjhzMUC4O|E9N2F-
HCT116 M1XNOmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NFv4R|Q1QCCqcoO= Mln5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEO4MlMh|ryPLh?= NHLmcVI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEGxNFg4OSd-MkixNVA5PzF:L3G+
PANC1 M4L6WGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M2rXUFQ5KGi{cx?= NX\UcIZ2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQRW5EOSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOFcvQDNizszNMi=> NHHWfJo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEGxNFg4OSd-MkixNVA5PzF:L3G+
HepG2 MV7BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MX:0PEBpenN? MlLhRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZYDHNkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNEmuNFIh|ryPLh?= MkfrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjhzMUC4O|EoRjJ6MUGwPFcyRC:jPh?=
BCG823 M33LNmN6fG:2b4jpZ4l1gSCjc4PhfS=> Mkj3OFghcHK| MV;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDCR2c5OjNiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMD6xJO69VS5? MlHQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjhzMUeyNFIoRjJ6MUG3NlAzRC:jPh?=
A549 MoP2R5l1d3SxeHnjbZR6KGG|c3H5 NFX3R5o1QCCqcoO= M2f2b2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzNj6xJO69VS5? MlrXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjhzMUeyNFIoRjJ6MUG3NlAzRC:jPh?=
HepG2 MVLDfZRwfG:6aXPpeJkh[XO|YYm= NWXj[ldEPDhiaILz NEjFVnFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG3MlIh|ryPLh?= MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDFzN{KwNkc,OjhzMUeyNFI9N2F-
EC9706 NYPFSmVwSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NXzaRZF2PDhiaILz NW\zNI5PSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDFR|k4ODZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI{NjJ4IN88UU4> M2GzclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MUG5NlAxLz5{OEGxPVIxODxxYU6=
ECA109 Mn3HRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MljiOFghcHK| M4jpXWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iRVPBNVA6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzNE4zPSEQvF2u MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDFzOUKwNEc,OjhzMUmyNFA9N2F-
K562 NGTCT4JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUDpfFZoPDhiaILz MYLHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDXV3QyKGG|c3H5MEBKSzVyIE2gN|gvPThizszNMi=> M3y5O|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MUK2OFM3Lz5{OEGyOlQ{PjxxYU6=
KKU-M214 NIfwRnpEgXSxdH;4bYNqfHliYYPzZZk> NHfvXZU4OiCqcoO= M3v2emN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGtMXS2PMkG0JINmdGy|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBi\nSncjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gN{44PiEQvF2u NHXKSHk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEG0NFU6Oid-MkixOFA2QTJ:L3G+
HL60 Mne3RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M3j4Z|Q5KGi{cx?= NEDQOm5CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjMOlAh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UV{Bie3OjeTygTWM2OCB;IEGuOlIh|ryPLh?= MkLoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjhzNUK0N|AoRjJ6MUWyOFMxRC:jPh?=
NCI-H1299 M1fOWWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M1Xx[|Q5KGi{cx?= MUDBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE6FST3INVI6QSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRUKGG|c3H5MEBKSzVyIE2gPE46OSEQvF2u M2npelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MUWyOFMxLz5{OEG1NlQ{ODxxYU6=
MCF7 MmLTRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MlrjO|IhcHK| M1LReWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMT63OUDPxE1w NEHYW4s9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEG2OVc{QCd-MkixOlU4Ozh:L3G+
Bel7402 MX;BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NWnXeFVFPzJiaILz MWrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEKnbEe0NFIh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKuNlUh|ryPLh?= NILqN3A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEG2OVc{QCd-MkixOlU4Ozh:L3G+
MGC803 MUDBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MlzxO|IhcHK| M3q5PGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVfDPFA{KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlEzKM7:TT6= NUntcHc2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkixOlU4OzhpPkK4NVY2PzN6PD;hQi=>
K562 MV3BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NIrkPIo4OiCqcoO= M2jESmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iS{W2NkBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz61OEDPxE1w MnG0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjhzNkW3N|goRjJ6MU[1O|M5RC:jPh?=
HepG2 MWnDfZRwfG:6aXPpeJkh[XO|YYm= MV20PEBpenN? Mkn3R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFyLkWzJO69VS5? NVjGOmE1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkixO|QyODdpPkK4NVc1OTB5PD;hQi=>
Hep3B MYTDfZRwfG:6aXPpeJkh[XO|YYm= NXe4fWFDPDhiaILz NUOweYl4S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyM1KgZ4VtdHNiYYPz[ZN{\WRiYYOg[5Jwf3SqIHnubIljcXSrb36gZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IES5MlczKM7:TT6= M4LJT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MUe0NVA4Lz5{OEG3OFExPzxxYU6=
MCF7 MnrtR5l1d3SxeHnjbZR6KGG|c3H5 M{TsUVczKGi{cx?= NX3KVXlxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nliU2LCJIF{e2G7LDDJR|UxKD1iMT60JO69VS5? NYfObW1URGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkiyNVkxPDZpPkK4NlE6ODR4PD;hQi=>
HCT116 Ml[5R5l1d3SxeHnjbZR6KGG|c3H5 NWHsXFNQPzJiaILz MkDaR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDd{IHjyd{BjgSCVUlKgZZN{[XluIFnDOVAhRSBzOD60JO69VS5? MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDJzOUC0Okc,Ojh{MUmwOFY9N2F-
HuH7 MV\DfZRwfG:6aXPpeJkh[XO|YYm= M17OeVczKGi{cx?= M4fNb2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGh2UDdiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDJzIN88UU4> NVezT2lZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkiyNVkxPDZpPkK4NlE6ODR4PD;hQi=>
A549 NXvDdmNDS3m2b4TvfIlkcXS7IHHzd4F6 NESxT3EzPCCqcoO= MWfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxMlIh|ryPLh?= NHLiTVc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEK1OFY6Pyd-MkiyOVQ3QTd:L3G+
HeLa MXrDfZRwfG:6aXPpeJkh[XO|YYm= NHnPXGszPCCqcoO= MYPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxMlQh|ryPLh?= NXjzfnJRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkiyOVQ3QTdpPkK4NlU1Pjl5PD;hQi=>
HepG2 M3j5NWN6fG:2b4jpZ4l1gSCjc4PhfS=> MYeyOEBpenN? M3;aWGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyNjRizszNMi=> MnXyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh{NUS2PVcoRjJ6MkW0Olk4RC:jPh?=
COLO205 NFLVcIdEgXSxdH;4bYNqfHliYYPzZZk> MWCyOEBpenN? Mn\YR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR29NVzJyNTDj[YxteyCjZoTldkAzPCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOS57IN88UU4> MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDJ3NE[5O{c,Ojh{NUS2PVc9N2F-
HepG2 NXvS[o5IS3m2b4TvfIlkcXS7IHHzd4F6 NH3B[ZFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyMlEh|ryPLh?= MnfiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh{NkK1NlcoRjJ6Mk[yOVI4RC:jPh?=
Hep3B NWntPJJGS3m2b4TvfIlkcXS7IHHzd4F6 MYXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZA{SiClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{Lk[2JO69VS5? MlzXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh{NkK1NlcoRjJ6Mk[yOVI4RC:jPh?=
Bel7402 MUXBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M4\wWVczKGi{cx?= MnmyRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCEZXy3OFAzKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDDR2suQCCjc4PhfUwhUUN3MDC9JFUvQTRizszNMi=> MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDNyMUixOUc,Ojh|MEG4NVU9N2F-
LO2 MlH0RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NX;mVlRRPzJiaILz NV7obmhOSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDMU|Ih[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IFPDT{05KGG|c3H5MEBKSzVyIE2gN|IvPTR4IN88UU4> M3XrdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6M{CxPFE2Lz5{OEOwNVgyPTxxYU6=
HCT116 NVzCS4dqS3m2b4TvfIlkcXS7IHHzd4F6 MlS0R5l1d3SxeHnjbZR6KGmwIHj1cYFvKEiFVEGxOkBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJkh[nliTWTUJIF{e2G7LDDJR|UxKD1iNEGg{txONg>? NV;hfG0{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkizN|Q3PTRpPkK4N|M1PjV2PD;hQi=>
MCF7 MWnDfZRwfG:6aXPpeJkh[XO|YYm= NFq3bIpEgXSxdH;4bYNqfHliaX6gbJVu[W5iTVPGO{Bk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJkh[nliTWTUJIF{e2G7LDDJR|UxKD1iNEGuOUDPxE1w MonxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh|M{S2OVQoRjJ6M{O0OlU1RC:jPh?=
HeLa M{\FZmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MXm0PEBpenN? MX3BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEinTHGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDlwMEKg{txONg>? MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDN4M{S0OEc,Ojh|NkO0OFQ9N2F-
HepG2 MkC4RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MnyyOFghcHK| NEH2OmFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxN{4{OSEQvF2u M{HwVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6M{[zOFQ1Lz5{OEO2N|Q1PDxxYU6=
BGC823 NXnnUGx4SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MoSyOFghcHK| NVTRVWp1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDCS2M5OjNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE4NjN5IN88UU4> M4TpRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6M{[zOFQ1Lz5{OEO2N|Q1PDxxYU6=
SW1116 M2e5T2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NXrieHMyPDhiaILz NV7nSWY4SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|EyOTZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE5NjV{IN88UU4> NFvVTms9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEO2N|Q1PCd-MkizOlM1PDR:L3G+
Hep3B M3rQeWN6fG:2b4jpZ4l1gSCjc4PhfS=> NIrxN|dEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XB|QjDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNU46KM7:TT6= NU\xWGt6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkizO|E3PzZpPkK4N|cyPjd4PD;hQi=>
MCF7 MmnNR5l1d3SxeHnjbZR6KGG|c3H5 NUDZfIhKS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzNEDPxE1w NI\TOlk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEO3NVY4Pid-MkizO|E3PzZ:L3G+
HepG2 MWXDfZRwfG:6aXPpeJkh[XO|YYm= NIqyVJZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzNk43KM7:TT6= MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDN5MU[3Okc,Ojh|N{G2O|Y9N2F-
A549 NELVe3dEgXSxdH;4bYNqfHliYYPzZZk> M3nBVWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iM{iuNkDPxE1w NVy5N3BXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkizO|E3PzZpPkK4N|cyPjd4PD;hQi=>
MCF7 M3nVN2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NUD5bXRLPDhidH:gO|IhcHK| M3\4OWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDpcoN2[mG2ZXSg[o9zKDR6IITvJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA4NjZ5IN88UU4> NXjsXolbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkizPVUzOThpPkK4N|k2OjF6PD;hQi=>
A549 NIX4VphCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MUe0PEB1dyB5MjDodpM> NEjNSWxCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgbY5kfWKjdHXkJIZweiB2ODD0c{A4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTBwNkWg{txONg>? M3:xNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6M{m1NlE5Lz5{OEO5OVIyQDxxYU6=
SGC7901 NICxe3ZCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MX60PEB1dyB5MjDodpM> MlPnRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVR1O3PVAyKGOnbHzzJIlv[3WkYYTl[EBnd3JiNEigeI8hPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF|LkK1JO69VS5? NFGxRZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEO5OVIyQCd-MkizPVUzOTh:L3G+
HepG2 NInHR4NCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MXu0PEB1dyB5MjDodpM> NFf4ZWRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIlv[3WkYYTl[EBnd3JiNEigeI8hPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF5LkS0JO69VS5? Mme4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh|OUWyNVgoRjJ6M{m1NlE5RC:jPh?=
PC3 MkPhRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MWq0PEB1dyB5MjDodpM> M1HtfGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUFOzJINmdGy|IHnuZ5Vj[XSnZDDmc5IhPDhidH:gO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFM5NjZzIN88UU4> Mn[wQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh|OUWyNVgoRjJ6M{m1NlE5RC:jPh?=
MCF7 NETYSJlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUm0PEBpenN? MULHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGdKPTBiPTCxMlY4KM7:TT6= MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDRyMEKzOUc,Ojh2MECyN|U9N2F-
A549 M1;qSWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIPybJc1QCCqcoO= NXK1eXBoT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hOi5yOTFOwG0v NEfsVFQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OESwNFI{PSd-Mki0NFAzOzV:L3G+
DU145 M2XiW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1m3NVQ5KGi{cx?= NU\uc4FmT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hTFVzNEWgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFOUQjDhd5NigSxiR1m1NEA:KDVwOEKg{txONg>? NGHyWVE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OESwNFI{PSd-Mki0NFAzOzV:L3G+
T47D M2LGV2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 MYS0PEBpenN? Mk\wRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCWNEfEJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMj6xJO69VS5? M{Dtb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NECwNlM5Lz5{OESwNFI{QDxxYU6=
A549 MWDBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M3KyS|Q5KGi{cx?= NV7l[IR2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOU4yKM7:TT6= NE[weW89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OESwNFI{QCd-Mki0NFAzOzh:L3G+
HepG2 M{e0bGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NIjRZ4M1QCCqcoO= MWLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEincFeyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{MD6xJO69VS5? MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDRyMEKzPEc,Ojh2MECyN|g9N2F-
HCT116 NVvROW56SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MYG0PEBpenN? NXzOUFZFSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI3NjJizszNMi=> MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDRyMEKzPEc,Ojh2MECyN|g9N2F-
MCF7 Ml;XR5l1d3SxeHnjbZR6KGG|c3H5 NX\RVlZlS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyxiSVO1NEA:KDdwOTFOwG0v NGLLfG89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OESzNVM1OSd-Mki0N|E{PDF:L3G+
HepG2 MoHmR5l1d3SxeHnjbZR6KGG|c3H5 NVXlZ2x{S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNuIFnDOVAhRSB6LkGg{txONg>? MlHQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh2M{GzOFEoRjJ6NEOxN|QyRC:jPh?=
HCT116 MXHDfZRwfG:6aXPpeJkh[XO|YYm= M4XvOGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDFzNjDj[YxteyxiSVO1NEA:KDlwOTFOwG0v Ml3iQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh2M{GzOFEoRjJ6NEOxN|QyRC:jPh?=
PC3 NUnyd3hqS3m2b4TvfIlkcXS7IHHzd4F6 MYW0PEBpenN? Mkf5R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxMlIh|ryPLh?= MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDR|MUi4NUc,Ojh2M{G4PFE9N2F-
A549 MmDpR5l1d3SxeHnjbZR6KGG|c3H5 Mm\TOFghcHK| M33WXmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEvPiEQvF2u NXTTNoE1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki0N|E5QDFpPkK4OFMyQDhzPD;hQi=>
HeLa Mk\wR5l1d3SxeHnjbZR6KGG|c3H5 M1u5TFQ5KGi{cx?= MmjYR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNU45PiEQvF2u MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDR|MUi4NUc,Ojh2M{G4PFE9N2F-
DU145 NGHhN4xEgXSxdH;4bYNqfHliYYPzZZk> NVO0[mpJPDhiaILz Ml;BR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSHUyPDViY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIvOThizszNMi=> Mnm2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh2M{G4PFEoRjJ6NEOxPFgyRC:jPh?=
MDA-MB-231 NF7lR5NEgXSxdH;4bYNqfHliYYPzZZk> M4HSVFQ5KGi{cx?= M3jHN2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj2yN|Eh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IESuN|Mh|ryPLh?= M3\RZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NEOxPFgyLz5{OESzNVg5OTxxYU6=
HGC27 Ml;tR5l1d3SxeHnjbZR6KGG|c3H5 NXvu[IdYPDhiaILz MVTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIS2MzPyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVQvPzJizszNMi=> Ml;ZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh2M{G4PFEoRjJ6NEOxPFgyRC:jPh?=
MGC803 NUf5XmFsSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MX:3NkBpenN? MlvQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPR1O4NFMh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IE[uOVYh|ryPLh?= M2nCUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NEW2NFMyLz5{OES1OlA{OTxxYU6=
HGC27 MYLBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? Mo\EO|IhcHK| NFfJZmNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjHR|I4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC4MlIzKM7:TT6= M3jBN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NEW2NFMyLz5{OES1OlA{OTxxYU6=
NCI-H1650 NV\0OGZCSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MXi3NkBpenN? M3;nb2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWgyPjVyIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOi53MjFOwG0v M3jiVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NEW2NFMyLz5{OES1OlA{OTxxYU6=
HCT116 NX60UlY1SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NEPXO3g4OiCqcoO= NHzQPFdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFEyPiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOE4yPiEQvF2u NYqy[HBiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki0OVgyOzNpPkK4OFU5OTN|PD;hQi=>
PC3 Ml7WRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MkDVO|IhcHK| NVzpSZg4SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEK0MlM{KM7:TT6= MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDR3OEGzN{c,Ojh2NUixN|M9N2F-
MCF7 NEPPXIRCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MYe3NkBpenN? MYPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ6LkezJO69VS5? NYjiR5VJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki0OVgyOzNpPkK4OFU5OTN|PD;hQi=>
HepG2 NGn2T2RCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MUG3NkBpenN? NGf6S5dCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyPU4xPyEQvF2u NGe0NHQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OES1PFE{Oyd-Mki0OVgyOzN:L3G+
Caco2 NVzTTJV2S3m2b4TvfIlkcXS7IHHzd4F6 Mn;nNlQhcHK| Mle0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR4FkdzJiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgNlQhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFMyKM7:TT6= MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDR4M{e4OUc,Ojh2NkO3PFU9N2F-
HeLa Mkn3R5l1d3SxeHnjbZR6KGG|c3H5 NF;Jc|Y4OiCqcoO= MYjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA4OiCqcoOgZpkhX1OWODDhd5NigSxiSVO1NEA:KDF|Lkmg{txONg>? NGK5bYI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OES4PFg3Oid-Mki0PFg5PjJ:L3G+
HT-29 MYfBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M3;yTVczKGi{cx?= MlLvRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKVD2yPUBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iND65JO69VS5? M3zNPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NEm0NlUyLz5{OES5OFI2OTxxYU6=
PC3 NYr2VFN4SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NGDpPFI4OiCqcoO= MnHvRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCSQ{OgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ2LkOg{txONg>? NULtUGRLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki0PVQzPTFpPkK4OFk1OjVzPD;hQi=>
HepG2 NHX3WFVCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NFX2eVU4OiCqcoO= M4\kd2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXwS|Ih[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEK5MlEh|ryPLh?= NWP3WJFORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki0PVQzPTFpPkK4OFk1OjVzPD;hQi=>
SW620 M1rlXmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M4\sXlczKGi{cx?= NVr1T2R2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|YzOCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE4xQCEQvF2u M2W2b|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NUK1PFQ2Lz5{OEWyOVg1PTxxYU6=
CFPAC-1 NHOwXG5CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MVi3NkBpenN? M4PyUmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1\QRWMuOSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE4yPCEQvF2u NXnJPXBjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki1NlU5PDVpPkK4OVI2QDR3PD;hQi=>
WI38 MmPrR5l1d3SxeHnjbZR6KGG|c3H5 Ml7kO|IhcHK| MUjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDXTVM5KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlk1KM7:TT6= NWe5RpRORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki1NlU5PDVpPkK4OVI2QDR3PD;hQi=>
HeLa MoDtRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MYG3NkBpenN? MmTGRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZVzhJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB6LkixJO69VS5? NYjFfYYzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki1NlU5PDVpPkK4OVI2QDR3PD;hQi=>
HepG2 NHzxcFJCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MX[3NkBpenN? NVXkeldKSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gPE46KM7:TT6= NYrKU2hwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki1NlU5PDVpPkK4OVI2QDR3PD;hQi=>
HCT116 MnHlR5l1d3SxeHnjbZR6KGG|c3H5 M3PWXVQ5KGi{cx?= NWXGT3h7S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOFEvQSEQvF2u NUe0Z2xtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki1N|I3PjlpPkK4OVMzPjZ7PD;hQi=>
A549 MV3DfZRwfG:6aXPpeJkh[XO|YYm= Mlj5O|IhcHK| MofRR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBieyCmZXPy[YF{\SCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA4OiCqcoOgZpkhX1OWODDhd5NigSxiSVO1NEA:KDRwNzFOwG0v Mn[3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh3NUi5O|AoRjJ6NUW4PVcxRC:jPh?=
HeLa NVnYNnBCS3m2b4TvfIlkcXS7IHHzd4F6 NULOR4ozPzJiaILz NG[2ZY5EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGG|c3Xzd4VlKGG|IHTlZ5Jm[XOnIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDd{IHjyd{BjgSCZU2S4JIF{e2G7LDDJR|UxKD1iNT6zJO69VS5? Ml;IQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh3NUi5O|AoRjJ6NUW4PVcxRC:jPh?=
MCF7 NE\hXmxEgXSxdH;4bYNqfHliYYPzZZk> MlL1O|IhcHK| NIfTWYREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGG|c3Xzd4VlKGG|IHTlZ5Jm[XOnIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDd{IHjyd{BjgSCZU2S4JIF{e2G7LDDJR|UxKD1iNT62JO69VS5? MnGwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh3NUi5O|AoRjJ6NUW4PVcxRC:jPh?=
WI38 Mn;NR5l1d3SxeHnjbZR6KGG|c3H5 NHXFdnA4OiCqcoO= NHzPS4VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBYUTN6IHPlcIx{KGG|c3Xzd4VlKGG|IHTlZ5Jm[XOnIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDd{IHjyd{BjgSCZU2S4JIF{e2G7LDDJR|UxKD1iNj64JO69VS5? NGL3Sog9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEW1PFk4OCd-Mki1OVg6PzB:L3G+
HCT116 M{HS[WN6fG:2b4jpZ4l1gSCjc4PhfS=> NEfpT3M1QCCqcoO= NYn2eVdyS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHzd4V{e2WmIHHzJIRm[3KnYYPlJIlvKGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0JO69VS5? MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDZ{M{ixOEc,Ojh4MkO4NVQ9N2F-
MCF7 NYLZO2xYS3m2b4TvfIlkcXS7IHHzd4F6 MXq0PEBpenN? NV;zS5I2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjc4Pld5Nm\CCjczDk[YNz\WG|ZTDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iND6zJO69VS5? M1rodFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NkKzPFE1Lz5{OE[yN|gyPDxxYU6=
HepG2 MX7DfZRwfG:6aXPpeJkh[XO|YYm= MlqzOFghcHK| NYSyVZRiS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYYPz[ZN{\WRiYYOg[IVkemWjc3WgbY4h[2WubDD2bYFjcWyrdImgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEWuN{DPxE1w MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDZ{M{ixOEc,Ojh4MkO4NVQ9N2F-
W138 NH7KT3REgXSxdH;4bYNqfHliYYPzZZk> M1TDdVQ5KGi{cx?= NWTlRYpnS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hXzF|ODDj[YxteyCjc4Pld5Nm\CCjczDk[YNz\WG|ZTDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNT63N{DPxE1w M2rnW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NkKzPFE1Lz5{OE[yN|gyPDxxYU6=
P388 M2HaTWN6fG:2b4jpZ4l1gSCjc4PhfS=> NXnFPY5lPzJiaILz NGnybHdEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBROzh6IHPlcIx{KGmwY4XiZZRm\CCob4KgO|IhcHK|IHL5JIFt[W2jcjDicJVmKGG|c3H5MEBKSzVyIE2gOU45KM7:TT6= MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDZ2OES2NEc,Ojh4NEi0OlA9N2F-
MOLT4 NGXTNGhEgXSxdH;4bYNqfHliYYPzZZk> NIThUYk4OiCqcoO= MmfhR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUW9NXDRiY3XscJMhcW6ldXLheIVlKG[xcjC3NkBpenNiYomgZYxidWG{IHLseYUh[XO|YYmsJGlEPTBiPTC2MlIh|ryPLh?= MkPJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh4NEi0OlAoRjJ6NkS4OFYxRC:jPh?=
HT-29 MnHJR5l1d3SxeHnjbZR6KGG|c3H5 MV23NkBpenN? MUnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{BqdmO3YnH0[YQh\m:{IEeyJIhzeyCkeTDhcIFu[XJiYnz1[UBie3OjeTygTWM2OCB;IEeuNkDPxE1w MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDZ2OES2NEc,Ojh4NEi0OlA9N2F-
K562 M3j4OmN6fG:2b4jpZ4l1gSCjc4PhfS=> MWC3NkBpenN? NWLsRmQyS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUzV4MjDj[YxteyCrbnP1ZoF1\WRiZn;yJFczKGi{czDifUBidGGvYYKgZox2\SCjc4PhfUwhUUN3MDC9JFMxNjVizszNMi=> MlKxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh4NEi0OlAoRjJ6NkS4OFYxRC:jPh?=
MCF7 MVPBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NFjhT4g1QCCqcoO= M{npemFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz6xPEDPxE1w NGTUSY09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OE[2Olg3OCd-Mki2OlY5PjB:L3G+
LNCAP MYTBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NFGwe|c1QCCqcoO= M2PMSmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTF7DRXAh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEWuNlEh|ryPLh?= MoriQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh4Nk[4OlAoRjJ6Nk[2PFYxRC:jPh?=
PC3 MYjDfZRwfG:6aXPpeJkh[XO|YYm= NXTyXpE5S3m2b4TvfIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzMEBKSzVyIE2gNU43KM7:TT6= NVnWcmNpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki2PVc6OjNpPkK4Olk4QTJ|PD;hQi=>
HL60 NV\mXHpTS3m2b4TvfIlkcXS7IHHzd4F6 NHTIe2FEgXSxdH;4bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIUFYxKGOnbHzzMEBKSzVyIE2gNk45KM7:TT6= MorPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh4OUe5NlMoRjJ6Nkm3PVI{RC:jPh?=
HCT116 MUPDfZRwfG:6aXPpeJkh[XO|YYm= M{SzO2N6fG:2b4jpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFEyPiClZXzsd{whUUN3MDC9JFE4NjBzIN88UU4> MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDZ7N{myN{c,Ojh4OUe5NlM9N2F-
HCT116 M4CwWmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MmTlOFghcHK| NYjHW|NpSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB3LkS3JO69VS5? NWfhVolHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3NVY1QTVpPkK4O|E3PDl3PD;hQi=>
CRL1790 NHXibnpEgXSxdH;4bYNqfHliYYPzZZk> NWT6WJhsPDhiaILz M3XaUGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNTVDF5OUCgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hOTBwMzFOwG0v NYDuXFZERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3NVY1QTVpPkK4O|E3PDl3PD;hQi=>
SW1573 NUjuOIJrSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= Mn3zOFghcHK| MWLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOZMUW3N{Bk\WyuczDh[pRmeiB2ODDodpMh[nliU2LCJIF{e2G7LDDHTVUxKD1iND6zJO69VS5? NV;Id2ZQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3NlgyODhpPkK4O|I5OTB6PD;hQi=>
HBL100 NIjTc|hCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MnzBOFghcHK| Mn\YRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQlyxNFAh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IGPSRkBie3OjeTygS2k2OCB;IEWuOUDPxE1w NGftZXA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEeyPFExQCd-Mki3NlgyODh:L3G+
hTERT-BJ MXLBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MnHQOFghcHK| NVPJZ|ljSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDoWGVTXC2ESjDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hPS53IN88UU4> MnW4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5MkixNFgoRjJ6N{K4NVA5RC:jPh?=
HeLa NILxO3VCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MWW0PEBpenN? NEfjbZRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IGPSRkBie3OjeTygS2k2OCB;IEG1JO69VS5? MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDd{OEGwPEc,Ojh5MkixNFg9N2F-
T47D NX;QdpNQSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MUS0PEBpenN? NWGwcplWSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDUOFdFKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGdKPTBiPTC0O{DPxE1w MlXGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5MkixNFgoRjJ6N{K4NVA5RC:jPh?=
WiDr MVvBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MoLUOFghcHK| MmfFRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCZaVTyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCVUlKgZZN{[XluIFfJOVAhRSB2OTFOwG0v NVL5XY9[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3NlgyODhpPkK4O|I5OTB6PD;hQi=>
A549 NGHW[2REgXSxdH;4bYNqfHliYYPzZZk> MX[0PEBpenN? MoC5R5l1d3SxeHnjbZR6KGmwIHj1cYFvKEF3NEmgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIlv[3WkYYTl[EBnd3JiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEO0MlQ4KM7:TT6= M4j5d|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6N{W0OFcxLz5{OEe1OFQ4ODxxYU6=
T24 MY\DfZRwfG:6aXPpeJkh[XO|YYm= M4jObFQ5KGi{cx?= M4XIS2N6fG:2b4jpZ4l1gSCrbjDoeY1idiCWMkSgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIlv[3WkYYTl[EBnd3JiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IESwMlE1KM7:TT6= MomxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5NUS0O|AoRjJ6N{W0OFcxRC:jPh?=
SPCA2 MYLDfZRwfG:6aXPpeJkh[XO|YYm= NYfKbJVkPDhiaILz MkHxR5l1d3SxeHnjbZR6KGmwIHj1cYFvKFOSQ1GyJINmdGy|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBqdmO3YnH0[YQh\m:{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0OE4{PCEQvF2u MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDd3NES3NEc,Ojh5NUS0O|A9N2F-
HepG2 NGT0OYxCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M2r3WlQ5KGi{cx?= MYXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEincFeyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{OD64JO69VS5? MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDd3NkK2OEc,Ojh5NU[yOlQ9N2F-
SKOV3 NIjqdXFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MYe0PEBpenN? MWrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFONT2[zJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|Mj61JO69VS5? NXjMOFVMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3OVYzPjRpPkK4O|U3OjZ2PD;hQi=>
NCI-H460 MkHQRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NFHtc3Q1QCCqcoO= MmP5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCQQ1mtTFQ3OCClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|Yh|ryPLh?= MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDd3NkK2OEc,Ojh5NU[yOlQ9N2F-
MCF7 NXfBTHcxSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MmXlOFghcHK| MnmzRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|OD61JO69VS5? M1TnN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6N{W2NlY1Lz5{OEe1OlI3PDxxYU6=
HL-7702 MYHDfZRwfG:6aXPpeJkh[XO|YYm= MVu0PEBpenN? MXHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIUE04PzB{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1PiEQvF2u MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDd3NkK2OEc,Ojh5NU[yOlQ9N2F-
EC109 NEDIbm9CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M2X1V|czKGi{cx?= NYDreGhZSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDFR|ExQSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOU4xOSEQvF2u NIn0ZmQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEe1PVg4Pid-Mki3OVk5PzZ:L3G+
MGC803 MnrHRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MXS3NkBpenN? M1exUWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVfDPFA{KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC2Mlg6KM7:TT6= MnfxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5NUm4O|YoRjJ6N{W5PFc3RC:jPh?=
MCF7 NEL2N2ZCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MVy3NkBpenN? NVyxXIdISW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC3MlIyKM7:TT6= MnHUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5NUm4O|YoRjJ6N{W5PFc3RC:jPh?=
GES-1 MnzFR5l1d3SxeHnjbZR6KGG|c3H5 MoPHO|IhcHK| MVHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDHSXMuOSClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDhwNUmg{txONg>? MnjlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5NUm4O|YoRjJ6N{W5PFc3RC:jPh?=
HGC27 NVfCVXVLSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MXK3NkBpenN? Mo\tRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKR1OyO{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUGuNFIh|ryPLh?= NGexVHI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEe1PVg4Pid-Mki3OVk5PzZ:L3G+
MCF7 M1vuUWN6fG:2b4jpZ4l1gSCjc4PhfS=> MX[3NkBpenN? MVjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPS5{IN88UU4> NEK1b5o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEe1PVg4Pyd-Mki3OVk5Pzd:L3G+
PC3 M4PRcWN6fG:2b4jpZ4l1gSCjc4PhfS=> M{juR|czKGi{cx?= NX;ielV2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWEN|IHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUOuO{DPxE1w Ml2yQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5NUm4O|coRjJ6N{W5PFc4RC:jPh?=
SKOV3 MYPDfZRwfG:6aXPpeJkh[XO|YYm= NXL5b5ROPzJiaILz MYXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTT29XOyClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJyLkig{txONg>? NFXZeXQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEe1PVg4Pyd-Mki3OVk5Pzd:L3G+
MDA-MB-231 M2m4dGN6fG:2b4jpZ4l1gSCjc4PhfS=> NFvsNWs4OiCqcoO= MVLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlQvPSEQvF2u NVv2VJBPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3OVk5PzdpPkK4O|U6QDd5PD;hQi=>
MGC803 MWPBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MXm0PEBpenN? NGKxOIRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3HR|gxOyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gPU44QSEQvF2u MmXhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5NkO2OFMoRjJ6N{[zOlQ{RC:jPh?=
PC3 MULBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NGrBOI41QCCqcoO= M1PGS2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUFOzJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMj64O{DPxE1w NVzwVXlmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3OlM3PDNpPkK4O|Y{PjR|PD;hQi=>
SH-SY5Y NF7JWnJCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NHPaSY41QCCqcoO= MV;BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOKLWPZOXkh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygS2k2OCB;IEGyJO69VS5? NHX5XmQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEe2N|Y1Pyd-Mki3OlM3PDd:L3G+
K562 MlW5RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? Mny5OFghcHK| Mnv3RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCNNU[yJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFfJOVAhRSBzOTFOwG0v MoHGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5NkO2OFcoRjJ6N{[zOlQ4RC:jPh?=
AGS NWK0XIEzSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MUG0PEBpenN? M4rzTGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQVfTJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFfJOVAhRSB{NTFOwG0v NYj6T4d1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3OlM3PDdpPkK4O|Y{PjR5PD;hQi=>
HeLa M1jtT2N6fG:2b4jpZ4l1gSCjc4PhfS=> Mkj1NlQhcHK| NUXmT3lXS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZYZ1\XJiMkSgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKuPUDPxE1w MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDh|OE[5OEc,Ojh6M{i2PVQ9N2F-
EC109 NHfFRZhCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M{LkUVQ5KGi{cx?= MmDURY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCHQ{GwPUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNj6yNUDPxE1w MlT4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh6M{i2PVUoRjJ6OEO4Olk2RC:jPh?=
MGC803 NWrUOIx6SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= Mmm4OFghcHK| NWP2VnAxSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNS2M5ODNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFcvPTJizszNMi=> M1PmV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OEO4Olk2Lz5{OEizPFY6PTxxYU6=
MKN45 NYX2cZF7SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M3XoZ|Q5KGi{cx?= NEHMS45CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3LUlQ2KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC4Mlg6KM7:TT6= M1zpNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OEO4Olk2Lz5{OEizPFY6PTxxYU6=
NCI-H1650 NF\RXYdCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MmnQOFghcHK| MlzwRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCQQ1mtTFE3PTBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE1NjJ3IN88UU4> M1HieFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OEO4Olk2Lz5{OEizPFY6PTxxYU6=
EC109 MmrRRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NYfB[lAxPDhiaILz MWLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEWFMUC5JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB4LkKxJO69VS5? NILXUmQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEi2N|M2PSd-Mki4OlM{PTV:L3G+
MGC803 M1m5bGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NF;obJc1QCCqcoO= NF3STXVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3HR|gxOyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gO{42OiEQvF2u M4DQc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OE[zN|U2Lz5{OEi2N|M2PTxxYU6=
MKN45 MWHBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NHjySYo1QCCqcoO= MXHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2NTkS1JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB6Lki5JO69VS5? MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDh4M{O1OUc,Ojh6NkOzOVU9N2F-
GES-1 M4XUTWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M3n2Z|Q5KGi{cx?= MmnzRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCJRWOtNUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iOT6wNkDPxE1w NWDIeHUzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki4OlM{PTVpPkK4PFY{OzV3PD;hQi=>
A549 NY\SOWZjSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= Ml;uOFghcHK| NWrmZWc{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNk46OiEQvF2u MkLvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh6NkOzOVUoRjJ6OE[zN|U2RC:jPh?=
NCI-H1650 NHL4ZpVCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M4W3blQ5KGi{cx?= NWTzeo82SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kuUDF4NUCgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF2LkK1JO69VS5? NHXFeVM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEi2N|M2PSd-Mki4OlM{PTV:L3G+
A549 NEjTd3VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1:zNVQ5KGi{cx?= MX3Hdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGdKPTBiPTC0MlIh|ryPLh?= MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDh7OEC4Nkc,Ojh6OUiwPFI9N2F-
PC3 Mkj3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEGxeoI1QCCqcoO= MW\Hdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDQR|Mh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IGPSRkBie3OjeTygS2k2OCB;IEGxMlch|ryPLh?= M{TYcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OEm4NFgzLz5{OEi5PFA5OjxxYU6=
PC3 NUTKNJZPS3m2b4TvfIlkcXS7IHHzd4F6 MVS0PEBpenN? NFLiZ3hEgXSxdH;4bYNqfHliaX6gbJVu[W5iUFOzJINmdGy|IHnuZ5Vj[XSnZDDmc5IhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFwMjFOwG0v NUTFNWl7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5NlM{QDFpPkK4PVI{OzhzPD;hQi=>
DU145 Mn3IR5l1d3SxeHnjbZR6KGG|c3H5 MUm0PEBpenN? MXLDfZRwfG:6aXPpeJkhcW5iaIXtZY4hTFVzNEWgZ4VtdHNiaX7jeYJifGWmIH\vdkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOi5zODFOwG0v MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDl{M{O4NUc,Ojh7MkOzPFE9N2F-
HCT116 MkjFR5l1d3SxeHnjbZR6KGG|c3H5 MnP6OFghcHK| NVXPZ|FWS3m2b4TvfIlkcXS7IHnuJIh2dWGwIFjDWFEyPiClZXzsd{BqdmO3YnH0[YQh\m:{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC4MlYzKM7:TT6= M{P4TlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OUKzN|gyLz5{OEmyN|M5OTxxYU6=
HT-29 MlToRY51cXS3bX;yJIF{e2G7 M{P3[FQ5KGi{cx?= NIPhPXdCdnSrdIXtc5Ih[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJINmdGxidnnhZoltcXS7IHnuZ5Vj[XSnZDDmc5IhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDRwNjFOwG0v M{fvc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OUK2O|Y1Lz5{OEmyOlc3PDxxYU6=
MCF7 NXGzVmVkSW62aYT1cY9zKGG|c3H5 NVS5fId7PDhiaILz M2jCVGFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlch[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDj[YxtKH[rYXLpcIl1gSCrbnP1ZoF1\WRiZn;yJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA2NjdizszNMi=> NVHXcWZYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5NlY4PjRpPkK4PVI3PzZ2PD;hQi=>
WI38 MX3DfZRwfG:6aXPpeJkh[XO|YYm= M1fZN|Q5KGi{cx?= NFzKd4ZEgXSxdH;4bYNqfHliaX6gbJVu[W5iV1mzPEBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIHPlcIwhfmmjYnnsbZR6KGmwY4XiZZRm\CCob4KgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFUvPyEQvF2u NEDzOlk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEmyOlc3PCd-Mki5NlY4PjR:L3G+
HepG2 NXfDPIR2SW62aYT1cY9zKGG|c3H5 M1:xeFQ5KGi{cx?= MWTBcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZYDHNkBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIHPlcIwhfmmjYnnsbZR6KGmwY4XiZZRm\CCob4KgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFYvQSEQvF2u M1\YS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OUK2O|Y1Lz5{OEmyOlc3PDxxYU6=
L02 M{O5XGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MYG0PEBpenN? MmOwRY51cS2ycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTECyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzOT6xJO69VS5? NVXybWNLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5OFcyPDlpPkK4PVQ4OTR7PD;hQi=>
AGS NWXKV2ZQSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MoDDOFghcHK| NHezSItCdnSrLYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBS3Mh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEK5MlYh|ryPLh?= M4DWc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OUS3NVQ6Lz5{OEm0O|E1QTxxYU6=
B16 NIT6SVFEgXSxdH;4bYNqfHliYYPzZZk> NU\aVpd2PzJiaILz MWfDfZRwfG:6aXPpeJkhcW5ibX;1d4UhSjF4IHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDpcoN2[mG2ZXSg[o9zKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzLkG5JO69VS5? NETrSFg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEm4O|YxPCd-Mki5PFc3ODR:L3G+
A549 MlPUR5l1d3SxeHnjbZR6KGG|c3H5 M37F[VczKGi{cx?= MUDDfZRwfG:6aXPpeJkhcW5iaIXtZY4hSTV2OTDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgbY5kfWKjdHXkJIZweiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iOD65JO69VS5? Ml63QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh7OEe2NFQoRjJ6OUi3OlA1RC:jPh?=
HepG2 MnfUR5l1d3SxeHnjbZR6KGG|c3H5 MW[3NkBpenN? MWDDfZRwfG:6aXPpeJkhcW5iaIXtZY4hUGWyR{KgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIlv[3WkYYTl[EBnd3JiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGwMlQh|ryPLh?= NHe3d3E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEm4O|YxPCd-Mki5PFc3ODR:L3G+
MCF7 MYDDfZRwfG:6aXPpeJkh[XO|YYm= MXq3NkBpenN? NIrJc|dEgXSxdH;4bYNqfHliaX6gbJVu[W5iTVPGO{Bk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJkhcW6ldXLheIVlKG[xcjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVQvPyEQvF2u NVnrO5d5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5PFc3ODRpPkK4PVg4PjB2PD;hQi=>
HL60 NFPJeXVCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NX:ySZZOOjRiaILz MmPPRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKTE[wJINmdGy|IITy[YF1\WRiZn;yJFI1KGi{czDt[YF{fXKnZDDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz62PUDPxE1w M{T4WVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MEO3PVUyLz5{OUCzO|k2OTxxYU6=
THP1 MWrBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NH;T[nkzPCCqcoO= Mk\yRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCWSGCxJINmdGy|IITy[YF1\WRiZn;yJFI1KGi{czDt[YF{fXKnZDDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iND64O{DPxE1w MlG4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlyM{e5OVEoRjJ7MEO3PVUyRC:jPh?=
PC3 NX[5TItiSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NGjZWZgzPCCqcoO= MlrNRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCSQ{OgZ4VtdHNidILlZZRm\CCob4KgNlQhcHK|IH3lZZN2emWmIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{Mz65OEDPxE1w MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTB|N{m1NUc,OjlyM{e5OVE9N2F-
HepG2 NFLQWIpCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NUnobIV1OjRiaILz Mn;LRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZYDHNkBk\WyuczD0doVifGWmIH\vdkAzPCCqcoOgcYVie3W{ZXSgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOwMlQ5KM7:TT6= M2\5OlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MEO3PVUyLz5{OUCzO|k2OTxxYU6=
SH-SY5Y NXjQZ3ZuSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MkSwOFghcHK| MXXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOKLWPZOXkh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygS2k2OCB;IEGxMlkh|ryPLh?= NYPWSGVWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmwOFA6PTRpPkK5NFQxQTV2PD;hQi=>
K562 Mn7FRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NGT4eIQ1QCCqcoO= MWjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEt3NkKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiR1m1NEA:KDF6LkWg{txONg>? MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTB2MEm1OEc,OjlyNEC5OVQ9N2F-
AGS NHjScJpCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M2XER|Q5KGi{cx?= MlXNRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDR2OgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiR1m1NEA:KDJ2Lk[g{txONg>? M4TsdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MESwPVU1Lz5{OUC0NFk2PDxxYU6=
EC109 NFnofG9CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NF;rOY01QCCqcoO= MkjLRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCHQ{GwPUBk\WyuczDhd5Nme3OnZDDhd{Bl\WO{ZXHz[UBqdiClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOk4zOSEQvF2u NV;SVW5GRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxNVM4PDVpPkK5NVE{PzR3PD;hQi=>
MGC803 M{Lpb2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 MnvtOFghcHK| NEG4R4FCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3HR|gxOyClZXzsd{Bie3Onc4Pl[EBieyCmZXPy[YF{\SCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPy53MjFOwG0v Mk\sQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlzMUO3OFUoRjJ7MUGzO|Q2RC:jPh?=
MKN45 M2DwcGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MXq0PEBpenN? NH23b|hCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3LUlQ2KGOnbHzzJIF{e2W|c3XkJIF{KGSnY4LlZZNmKGmwIHPlcIwhfmmjYnnsbZR6KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA5Njh7IN88UU4> MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTFzM{e0OUc,OjlzMUO3OFU9N2F-
NCI-H1650 NFTycopCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MVq0PEBpenN? Mlv6RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCQQ1mtTFE3PTBiY3XscJMh[XO|ZYPz[YQh[XNiZHXjdoVie2ViaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF2LkK1JO69VS5? NWrOe4lxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxNVM4PDVpPkK5NVE{PzR3PD;hQi=>
HL60 MoHiRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NEHONo44OiCqcoO= MmLKRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKTE[wJINmdGy|IHHmeIVzKDd{IHjyd{BjgSC2conwbIFvKGKudXWgd5RicW6rbnegZoF{\WRiaHXtZZRw[3m2b33leJJq[yCvZYToc4QtKEmFNUCgQUAzNjhizszNMi=> NGnrc|Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUGzNVYyPid-MkmxN|E3OTZ:L3G+
PC3 MnO4RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NWHVXZJFSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOjJwMEKg{txONg>? NUnmNYxJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxN|E3OTZpPkK5NVMyPjF4PD;hQi=>
EAC MV7DfZRwfG:6aXPpeJkh[XO|YYm= Ml\SOFghcHK| NGruWGhEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBGSUNiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB7LkKg{txONg>? M3HJVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MUOzNFM4Lz5{OUGzN|A{PzxxYU6=
EAC M3S2bWN6fG:2b4jpZ4l1gSCjc4PhfS=> M{jaPVQ5KGi{cx?= NXHQ[VdkS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhTUGFIHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nlidIL5dIFvKGKudXWg[ZhkdHW|aX;uJIF{e2G7LDDJR|UxKD1iOT62JO69VS5? MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTF|M{CzO{c,OjlzM{OwN|c9N2F-
MCF7 NE\UfZJEgXSxdH;4bYNqfHliYYPzZZk> M3\DVlQ5KGi{cx?= MVPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTBwMjFOwG0v MlXuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlzM{OwN|coRjJ7MUOzNFM4RC:jPh?=
MCF7 NWToR2ZzS3m2b4TvfIlkcXS7IHHzd4F6 NI\USFQ1QCCqcoO= NVzZd4h2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZYZ1\XJiNEigbJJ{KGK7IITyfZBidiCkbIXlJIV5[2y3c3nvckBie3OjeTygTWM2OCB;IEGwMlYh|ryPLh?= MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTF|M{CzO{c,OjlzM{OwN|c9N2F-
DLA NITxUopEgXSxdH;4bYNqfHliYYPzZZk> M2O1[FQ5KGi{cx?= Ml\iR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgSGxCKGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhfHK7cHHuJIJtfWViZYjjcJV{cW:wIHHzd4F6NCCLQ{WwJF0hOTBwNjFOwG0v MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTF|M{CzO{c,OjlzM{OwN|c9N2F-
DLA M1zIc2N6fG:2b4jpZ4l1gSCjc4PhfS=> MYq0PEBpenN? MYXDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W|ZTDEUGEh[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwIHPlcIwhfmmjYnnsbZR6KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOC56IN88UU4> MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTF|M{CzO{c,OjlzM{OwN|c9N2F-
A549 NVLHfmJUS3m2b4TvfIlkcXS7IHHzd4F6 NXn3bZJUPDhiaILz MoDBR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KHS{eYDhckBjdHWnIHX4Z4x2e2mxbjDhd5NigSxiSVO1NEA:KDFzLkKg{txONg>? NEDnZnM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUGzN|A{Pyd-MkmxN|MxOzd:L3G+
A549 M3uxZWN6fG:2b4jpZ4l1gSCjc4PhfS=> MlzJOFghcHK| MnnHR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFzLkSg{txONg>? MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTF|M{CzO{c,OjlzM{OwN|c9N2F-
MDA-MB-468 MnnmR5l1d3SxeHnjbZR6KGG|c3H5 MV:0PEBpenN? MlLDR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUS2PEBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK|IHL5JJRzgXCjbjDicJVmKGW6Y3z1d4lwdiCjc4PhfUwhUUN3MDC9JFQ1NjZizszNMi=> Mkm0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlzM{OwN|coRjJ7MUOzNFM4RC:jPh?=
MDA-MB-468 MoLUR5l1d3SxeHnjbZR6KGG|c3H5 NIr1[mk1QCCqcoO= NUDTXIk5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUSDLV3CMVQ3QCClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR2Lkmg{txONg>? NYr6coRRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxN|MxOzdpPkK5NVM{ODN5PD;hQi=>
SW620 M3rq[WFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M2\mclczKGi{cx?= NWrIWZBsSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|YzOCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE4xQCEQvF2u NXq3[otvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxN|MxPDZpPkK5NVM{ODR4PD;hQi=>
CFPAC-1 NGnVdnlCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M{DzfVczKGi{cx?= M3u1PGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1\QRWMuOSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE4yPCEQvF2u M1jwWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MUOzNFQ3Lz5{OUGzN|A1PjxxYU6=
WI38 NXPKSop6SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NYq3VmdsPzJiaILz M{G3fWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iV1mzPEBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD65OEDPxE1w NETtcJY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUGzN|A1Pid-MkmxN|MxPDZ:L3G+
A549 NX7FR2JjSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MlPoO|IhcHK| NF3ldGpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKuPEDPxE1w MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTF|M{C0Okc,OjlzM{OwOFY9N2F-
HeLa NXj2TVRTSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NXy1e2lKPzJiaILz NHO5XWFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEiuPFEh|ryPLh?= M3e5NFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MUOzNFQ3Lz5{OUGzN|A1PjxxYU6=
K562 M170XGN6fG:2b4jpZ4l1gSCjc4PhfS=> MX20PEBpenN? NHHtSlVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMPTZ{IHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iOT60PUDPxE1w MorWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlzM{OwOFkoRjJ7MUOzNFQ6RC:jPh?=
WM9 MXrDfZRwfG:6aXPpeJkh[XO|YYm= M3nmcVQ5KGi{cx?= Mn23R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gW206KGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTVwODFOwG0v NVK0XXhwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxN|MxPDlpPkK5NVM{ODR7PD;hQi=>
HEL MlPqR5l1d3SxeHnjbZR6KGG|c3H5 NYqzeokyPDhiaILz M1PKd2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhGVCClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF3Lkm4JO69VS5? NXX1N29jRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxN|MxPDlpPkK5NVM{ODR7PD;hQi=>
MDA-MB-231 NI\XfFhEgXSxdH;4bYNqfHliYYPzZZk> Mn\tOFghcHK| NGWzS2REgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOTEFvTVKtNlMyKGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTdwN{Sg{txONg>? MoHqQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlzM{OwOFkoRjJ7MUOzNFQ6RC:jPh?=
PC3 NXixR4pXS3m2b4TvfIlkcXS7IHHzd4F6 M2PuWFQ5KGi{cx?= M2X5TmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHBEOyClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF7Lki3JO69VS5? MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTF|M{C0PUc,OjlzM{OwOFk9N2F-
PC3 M3e2fGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NYD4e2FoPDhiaILz NGTVZ|lCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGDDN{Bk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iND63OUDPxE1w MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTF|M{C1NUc,OjlzM{OwOVE9N2F-
A549 M4HGSWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MnHoOFghcHK| NEP5dGpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEiuOFgh|ryPLh?= MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTF|M{C1NUc,OjlzM{OwOVE9N2F-
SGC7901 MVzBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M3\4OlQ5KGi{cx?= M3LFSmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU1fDO|kxOSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVAvQThizszNMi=> NHrCbXc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUGzN|A2OSd-MkmxN|MxPTF:L3G+
MGC803 NHviNWdCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NFrPWWY1QCCqcoO= M3G1S2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVfDPFA{KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOE4yPSEQvF2u NWK2fYtERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxN|MxPTFpPkK5NVM{ODVzPD;hQi=>
HT-29 MmrvR5l1d3SxeHnjbZR6KGG|c3H5 NYrZWHFpPDhiaILz MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bie3Onc4Pl[EBieyClZXzsJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC4MlMh|ryPLh?= NEXPXoo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUGzN|A3OSd-MkmxN|MxPjF:L3G+
HCT15 MlTzR5l1d3SxeHnjbZR6KGG|c3H5 NXXkbXB2PDhiaILz MYjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3QyPSClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gO{42OyEQvF2u NVPwcGdLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxO|Q5OTNpPkK5NVc1QDF|PD;hQi=>
Bel7402 MYrDfZRwfG:6aXPpeJkh[XO|YYm= Ml\KOFghcHK| NYj3bpFFS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSmWuN{SwNkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMkCuPVMh|ryPLh?= NHnofmc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUG3OFgyOyd-MkmxO|Q5OTN:L3G+
MCF7 NUW4W2NyS3m2b4TvfIlkcXS7IHHzd4F6 NHX2fnA1QCCqcoO= MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyPE46PyEQvF2u M1rDSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MUe0PFE{Lz5{OUG3OFgyOzxxYU6=
U937 MnfIRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NInhSHA1QCCqcoO= M4nHb2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iVUmzO{Bk\WyuczDpckBxemW|ZX7j[UBw\iC3YnXubY1mgCCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hQS53NjFOwG0v MoPkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl{MEKzPVgoRjJ7MkCyN|k5RC:jPh?=
HepG2 Mkj5RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MXG0PEBpenN? NYfhTGZZSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{BqdiCycnXz[Y5k\SCxZjD1ZoVvcW2neDDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUSuOVIh|ryPLh?= NVPlc4FxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmyNFI{QThpPkK5NlAzOzl6PD;hQi=>
A549 Ml3mRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NHLWUG01QCCqcoO= NHO0d45CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgbY4heHKnc3XuZ4Uhd2ZidXLlcolu\XhiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF3LkmzJO69VS5? NUjmSphORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmyNFI{QThpPkK5NlAzOzl6PD;hQi=>
A549 NELnXm5CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NFy3Omg1QCCqcoO= M1i1UmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUeuNFIh|ryPLh?= M3LtWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MkCyN|k5Lz5{OUKwNlM6QDxxYU6=
H7402 MYrBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NFHuWYY1QCCqcoO= NF6zT4JCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFi3OFAzKGOnbHzzJIlvKHC{ZYPlcoNmKG:oIIXi[Y5qdWW6IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzNz61PEDPxE1w MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTJyMkO5PEc,Ojl{MEKzPVg9N2F-
HepG2 M2L3WWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NXjCfmc2PDhiaILz M{D5PGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXwS|Ih[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG4MlM2KM7:TT6= M{\a[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MkCyN|k5Lz5{OUKwNlM6QDxxYU6=
H7402 M1LqOGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MlrLOFghcHK| NUnXXpdLSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIO|QxOiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlEvQDdizszNMi=> NWTzVldHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmyNFI{QThpPkK5NlAzOzl6PD;hQi=>
PLC/PRF/5 NFrNTmZCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= Mn\aOFghcHK| NYXPOHA3SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQUGMwWFKIL{WgZ4VtdHNiaX6gdJJme2WwY3Wgc4YhfWKnbnnt[Zgh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIzNjhzIN88UU4> MlXlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl{MEKzPVgoRjJ7MkCyN|k5RC:jPh?=
U937 Mn3PRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NY[zV2Y5PDhiaILz MUHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFV7M{egZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ6Lke2JO69VS5? MkTmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl{MEKzPVgoRjJ7MkCyN|k5RC:jPh?=
PLC/PRF/5 NFryT5JCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MU[0PEBpenN? MoX1RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCSTFOvVHJHNzViY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFM2NjZ4IN88UU4> M{WyXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MkCyN|k5Lz5{OUKwNlM6QDxxYU6=
ES2 M{m2[WFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MXK0PEBpenN? NWDJW4VqSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDFV|Ih[2WubIOgbY4heHKnc3XuZ4Uhd2ZidXLlcolu\XhiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN5LkC1JO69VS5? NIXIbZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUKwNlM6QCd-MkmyNFI{QTh:L3G+
U266 M{PaO2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 M1O1NFQ5KGi{cx?= MYfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFV{Nk[gZ4VtdHNiaX6gdJJme2WwY3Wgc4YhfWKnbnnt[Zgh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQ{NjR6IN88UU4> MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTJyMkO5PEc,Ojl{MEKzPVg9N2F-
HCT116 NYXCNZBJSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MYq0PEBpenN? M1\QSGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPUNVE3KGOnbHzzJIlvKHC{ZYPlcoNmKG:oIIXi[Y5qdWW6IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB2ND6wOkDPxE1w M{LQOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MkCyN|k5Lz5{OUKwNlM6QDxxYU6=
MCF7 NH3uSYpCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MkHtO|IhcHK| MlnIRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{LkO1JO69VS5? NEGzSXk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUKyN|A6QCd-MkmyNlMxQTh:L3G+
HCT116 NV7hR2JbSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NUTudlMzPDhiaILz MWTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiFVEGxOkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iOD62N|gh|ryPLh?= MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTJ{M{exO{c,Ojl{MkO3NVc9N2F-
143B M13sdGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MWO0PEBpenN? NIfmSWNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIEG0N2Ih[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEK1MlIyPiEQvF2u MmGyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl{MkO3NVcoRjJ7MkKzO|E4RC:jPh?=
MCF7 NXPrbZFMSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M364OVQ5KGi{cx?= NWS3OWpZSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzNk43OjZizszNMi=> NHzkTpk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUKyN|cyPyd-MkmyNlM4OTd:L3G+
HCT116 NUPXe3JjSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MnXCO|IhcHK| NVO3TmpLSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI6NjVizszNMi=> NIHtVHY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUKzNlU5Oyd-MkmyN|I2QDN:L3G+
SGC7901 MoXpRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NYPDZYhvPzJiaILz NIX6RpVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPHR|c6ODFiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFM1NjRizszNMi=> MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTJ|MkW4N{c,Ojl{M{K1PFM9N2F-
SMMC7721 NULkWmVLSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NWPnTG1TPzJiaILz MV\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFOPTVO3O|IyKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzO{45KM7:TT6= MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTJ|MkW4N{c,Ojl{M{K1PFM9N2F-
HuH7 M{jUOGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MXO3NkBpenN? NGC2VFlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFj1TFch[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEWuOlMh|ryPLh?= NIKybIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUOxOlU{Pid-MkmzNVY2OzZ:L3G+
HCT116 MkW5RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NX\0eo1GPzJiaILz MlrrRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGxMlI6KM7:TT6= MnHTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl|MU[1N|YoRjJ7M{G2OVM3RC:jPh?=
MGC803 NFz6U4pCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M334XFczKGi{cx?= M4\lUGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVfDPFA{KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyOU42PCEQvF2u M2nIflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7M{G2OVM3Lz5{OUOxOlU{PjxxYU6=
MGC803 M13xNmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NGTqTnY4OiCqcoO= NH20fpBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3HR|gxOyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gO{45PiEQvF2u MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTRyN{m0Okc,Ojl2MEe5OFY9N2F-
NCI-H1650 NIXEeI1CdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MX[3NkBpenN? MUTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE6FST3INVY2OCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVQvPjNizszNMi=> Ml\VQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2MEe5OFYoRjJ7NEC3PVQ3RC:jPh?=
PC3 NYXweYVlSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MlnOO|IhcHK| NUjkZmdvSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEK3MlYyKM7:TT6= MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTRyN{m0Okc,Ojl2MEe5OFY9N2F-
HL60 NG\FOlVCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MVq3NkBpenN? MVLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiONkCgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJwM{eg{txONg>? NI[w[FU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSwO|k5Oyd-Mkm0NFc6QDN:L3G+
Bel7402 NYWzRoo6SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M1zGdVczKGi{cx?= NV3EOFhYSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDC[Yw4PDB{IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyQC52OTFOwG0v NXTFTmc1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0NFc6QDNpPkK5OFA4QTh|PD;hQi=>
PC3 NXv0[XNqSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NFPiSHI4OiCqcoO= M3XXbGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUFOzJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{Mz64OkDPxE1w NXnKeWlCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0NFc6QDNpPkK5OFA4QTh|PD;hQi=>
EC9706 MlvJRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MV63NkBpenN? MkjDRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCHQ{m3NFYh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEWuNVMh|ryPLh?= M4\HbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NEe1NVU3Lz5{OUS3OVE2PjxxYU6=
EC109 NX3lelUzSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M{PR[VczKGi{cx?= M1f4N2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iRVOxNFkh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IE[uNFIh|ryPLh?= MlLOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2N{WxOVYoRjJ7NEe1NVU3RC:jPh?=
PC3 NXr4U2hDSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NHn5eYo4OiCqcoO= MkTWRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCSQ{OgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDZwMkeg{txONg>? M4XFXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NEe1NVU3Lz5{OUS3OVE2PjxxYU6=
MGC803 NITJVYFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MlTiO|IhcHK| NYm0fpZDSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNS2M5ODNiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFkvOjRizszNMi=> NH[3bnU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUS3OVE2Pid-Mkm0O|UyPTZ:L3G+
SMMC7721 NIrnXGtCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M1r5cFczKGi{cx?= NWPzfYdQSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTUW1EPzd{MTDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTNwNzFOwG0v MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTR5NUG1Okc,Ojl2N{WxOVY9N2F-
MCF7 MYLBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NVH6dFE3PzJiaILz M1qzfGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUiuO|Uh|ryPLh?= MnH1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2N{WxOVYoRjJ7NEe1NVU3RC:jPh?=
MCF7 NHzaW4pCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MnPMOFghcHK| NXnQZYduSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOU44QCEQvF2u NH\wenY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUS4Olk2PCd-Mkm0PFY6PTR:L3G+
HCT116 NELBW5pCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NIP0do81QCCqcoO= NIrzZWFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFEyPiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVcvOjVizszNMi=> MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTR6Nkm1OEc,Ojl2OE[5OVQ9N2F-
A549 MoXkRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MYm0PEBpenN? NIX2U2NCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG5MlUzKM7:TT6= NFLSem89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUS4Olk2PCd-Mkm0PFY6PTR:L3G+
HepG2 MmXyRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MlHQOFghcHK| NGnadZVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyN{43KM7:TT6= MoC5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2OE[5OVQoRjJ7NEi2PVU1RC:jPh?=
HeLa M1T3b2N6fG:2b4jpZ4l1gSCjc4PhfS=> MoX0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bie3Onc4Pl[EBieyCmZXPy[YF{\SCrbjDj[YxtKH[rYXLpcIl1gSCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyPEDPxE1w NEDRUGs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUS4PVM3OSd-Mkm0PFk{PjF:L3G+
A549 M1qwR2N6fG:2b4jpZ4l1gSCjc4PhfS=> MV\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGSnY4LlZZNmKGmwIHPlcIwhfmmjYnnsbZR6KGK7IF3UWEBie3OjeTygTWM2OCB;IEO2Mlgh|ryPLh?= NI\Keoc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUS4PVM3OSd-Mkm0PFk{PjF:L3G+
QSG7701 NWqyXmlsSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NWDBXHZHOjRiaILz Ml\IRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCTU1e3O|AyKGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDDR2suQCCjc4PhfUwhUUN3MDC9JFYvQTJizszNMi=> MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTR7OUS5NEc,Ojl2OUm0PVA9N2F-
SMMC7721 MUnBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NEfIemwzPCCqcoO= M2PjPWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU13NR|c4OjFiY3XscJMh[W[2ZYKgNlQhcHK|IHL5JGNEUy16IHHzd4F6NCCLQ{WwJF0hOTJwNEeg{txONg>? MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTR7OUS5NEc,Ojl2OUm0PVA9N2F-
QGY7703 NILG[GFCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NILSNXozPCCqcoO= MY\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFGJWUe3NFMh[2WubIOgZYZ1\XJiMkSgbJJ{KGK7IFPDT{05KGG|c3H5MEBKSzVyIE2gNVQvOiEQvF2u M3rWOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NEm5OFkxLz5{OUS5PVQ6ODxxYU6=
HepG2 MV3BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M4X6UVI1KGi{cx?= NFzvfo1CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDDR2suQCCjc4PhfUwhUUN3MDC9JFE2Njd2IN88UU4> MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTR7OUS5NEc,Ojl2OUm0PVA9N2F-
HL60 MXjBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MYi3NkBpenN? MVfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiONkCgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJwM{eg{txONg>? MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTV{NEeyPEc,Ojl3MkS3Nlg9N2F-
Bel7402 M1S0WWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 Ml\3O|IhcHK| MYDBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEKnbEe0NFIh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG4MlQ6KM7:TT6= Ml;CQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3MkS3NlgoRjJ7NUK0O|I5RC:jPh?=
PC3 MU\BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M4XOXFczKGi{cx?= MnXrRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCSQ{OgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ|Lki2JO69VS5? MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTV{NEeyPEc,Ojl3MkS3Nlg9N2F-
MGC803 MmrYRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NYDpfmMzPzJiaILz NGnGW5lCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3HR|gxOyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gPE43PiEQvF2u Mk\CQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl4M{WxOlUoRjJ7NkO1NVY2RC:jPh?=
PC3 M1rUUWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MXm3NkBpenN? NFfIdXFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGDDN{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUKuN|Mh|ryPLh?= MnHVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl4M{WxOlUoRjJ7NkO1NVY2RC:jPh?=
GES-1 NFn0V5dCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NILNZ5U4OiCqcoO= NEWxS|VCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFfFV{0yKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNk42OSEQvF2u MoX2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl4M{WxOlUoRjJ7NkO1NVY2RC:jPh?=
A549 NWPBbpl2SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NVXvbnFLPzJiaILz MojZRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDNUS5JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMz6xPEDPxE1w NHWyR2c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OU[zOVE3PSd-Mkm2N|UyPjV:L3G+
TE1 M2jMVmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M4fDdFczKGi{cx?= MVvBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFSHMTDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTZwNUOg{txONg>? MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTZ|NUG2OUc,Ojl4M{WxOlU9N2F-
HL60 NYHOclYzSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MorhO|IhcHK| NWXEUXpKSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIUFYxKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlQ3KM7:TT6= MmHUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl4M{WxOlkoRjJ7NkO1NVY6RC:jPh?=
Bel7402 MWXBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M4PMNlczKGi{cx?= NEC2bnVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFLlcFc1ODJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE5Njl5IN88UU4> M1fZcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NkO1NVY6Lz5{OU[zOVE3QTxxYU6=
SGC7901 NEDHeHdCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NE[0UG04OiCqcoO= Mle3RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVR1O3PVAyKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxPU45PCEQvF2u MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTZ|NUG2PUc,Ojl4M{WxOlk9N2F-
MCF7 NIToN2JCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M{Hu[|czKGi{cx?= MXrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ4LkmxJO69VS5? NHXtXZE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OU[zOVE3QSd-Mkm2N|UyPjl:L3G+
Caco2 NV\YeHpCSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NUS0WHYxPzJiaILz MYTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEOjY3:yJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|OD63O{DPxE1w NYTBTlZ[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm2N|UyPjlpPkK5OlM2OTZ7PD;hQi=>
MCF7 MmXWR5l1d3SxeHnjbZR6KGG|c3H5 NUXrR|lTPDhiaILz Mor1R5l1d3SxeHnjbZR6KGmwIHj1cYFvKE2FRkegZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIlv[3WkYYTl[EBnd3JiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG2Mlch|ryPLh?= NVXWOVhJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm2OVcyODBpPkK5OlU4OTByPD;hQi=>
MDA-MB-231 NFjqOYNEgXSxdH;4bYNqfHliYYPzZZk> NUL6bW5JPDhiaILz NXfRS|JLS3m2b4TvfIlkcXS7IHnuJIh2dWGwIF3ERU1OSi1{M{GgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIlv[3WkYYTl[EBnd3JiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEO1MlkyKM7:TT6= NI\yb2w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OU[1O|ExOCd-Mkm2OVcyODB:L3G+
DU145 Ml61R5l1d3SxeHnjbZR6KGG|c3H5 MnfOOFghcHK| MUfDfZRwfG:6aXPpeJkhcW5iaIXtZY4hTFVzNEWgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIlv[3WkYYTl[EBnd3JiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEO5MlE4KM7:TT6= NWTITJZMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm2OVcyODBpPkK5OlU4OTByPD;hQi=>
A549 M1TVO2N6fG:2b4jpZ4l1gSCjc4PhfS=> NYmw[YpuPDhiaILz M1m4SWN6fG:2b4jpZ4l1gSCrbjDoeY1idiCDNUS5JINmdGy|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBqdmO3YnH0[YQh\m:{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzPU45PiEQvF2u Mo\JQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl4NUexNFAoRjJ7NkW3NVAxRC:jPh?=
HepG2 NEL6W3JEgXSxdH;4bYNqfHliYYPzZZk> MlixOkBl[Xm| NUXGNXdZS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPiCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF{IN88UU4> MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTd6NkSzOkc,Ojl5OE[0N|Y9N2F-
SGC7901 M360UWN6fG:2b4jpZ4l1gSCjc4PhfS=> M2DIUVYh\GG7cx?= MV3DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTS2M4QTBzIHPlcIx{KGGodHXyJFYh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOiEQvF2u Moe5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl5OE[0N|YoRjJ7N{i2OFM3RC:jPh?=
HepG2 MV\BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NXj2T2JHSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzLkeg{txONg>? M4[yUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7N{m4PFI3Lz5{OUe5PFgzPjxxYU6=
HeLa MY\BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MnrxRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZVzhJINmdGy|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEvQCEQvF2u MlHlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl5OUi4NlYoRjJ7N{m4PFI3RC:jPh?=
MCF7 NG\nb5ZCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M2ewO2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDifUBOXFRiYYPzZZktKEmFNUCgQUAyNjhizszNMi=> NUTRXohZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm3PVg5OjZpPkK5O|k5QDJ4PD;hQi=>
COLO205 Mly4RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MnL4RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCFT1zPNlA2KGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFwOTFOwG0v NFXPPJg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUe5PFgzPid-Mkm3PVg5OjZ:L3G+
HEK293 NUH1eHUzSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M{j5N2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFXLNlk{KGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF7Lk[g{txONg>? MnXaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl5OUi4NlYoRjJ7N{m4PFI3RC:jPh?=
A549 NX3aZpM6S3m2b4TvfIlkcXS7IHHzd4F6 M2TPUmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[nliTWTTJIF{e2G7LDDJR|UxKD1iMz61NkDPxE1w MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTh2M{GwN{c,Ojl6NEOxNFM9N2F-
HCT116 NF7XXYNEgXSxdH;4bYNqfHliYYPzZZk> Mn7KR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{KGK7IF3UV{Bie3OjeTygTWM2OCB;IEWuOVMh|ryPLh?= NXLlOm1WRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm4OFMyODNpPkK5PFQ{OTB|PD;hQi=>
HeLa NXPBRWtTS3m2b4TvfIlkcXS7IHHzd4F6 NYmzW|dGPzJiaILz M3POVWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[XO|ZYPz[YQh[XNiZHXjdoVie2ViaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDdizszNMi=> MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTlyOES0N{c,Ojl7MEi0OFM9N2F-
McCoy M{jU[2N6fG:2b4jpZ4l1gSCjc4PhfS=> NXrUUFhKPzJiaILz NWnTW2IyS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVWOFb4mgZ4VtdHNiYYPz[ZN{\WRiYYOg[IVkemWjc3WgbY4h[2WubDD2bYFjcWyrdImgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG1Mlch|ryPLh?= NFHTOlI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUmwPFQ1Oyd-Mkm5NFg1PDN:L3G+
PC3 NVz2fWtLSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MWq0PEBpenN? NWrJc443SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEiuOFUh|ryPLh?= MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTl3OEe2N{c,Ojl7NUi3OlM9N2F-
HT-29 MkXmRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NYrUZ2pHPDhiaILz MlTQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKVD2yPUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMkKuNlMh|ryPLh?= M3jLeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7OUW4O|Y{Lz5{OUm1PFc3OzxxYU6=
HeLa MYHDfZRwfG:6aXPpeJkh[XO|YYm= NV;ONIF2PDhiaILz MUfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzNE4zOSEQvF2u M1\DR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMEC3OVY1Lz5|MECwO|U3PDxxYU6=
HepG2 MWrDfZRwfG:6aXPpeJkh[XO|YYm= MXi0PEBpenN? MWfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|YvPjJizszNMi=> NEP1PWY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MECwO|U3PCd-M{CwNFc2PjR:L3G+
2008 MWrDfZRwfG:6aXPpeJkh[XO|YYm= NYPw[25iS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hOjByODDj[YxteyxiSVO1NEA:KDZizszNMi=> MlnHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzByM{W1OFEoRjNyMEO1OVQyRC:jPh?=
IGROV1 NHrGWFdEgXSxdH;4bYNqfHliYYPzZZk> M2PjTFczKGi{cx?= M4fuO2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGlIWk:YMTDj[YxteyCjZoTldkA4OiCqcoOsJGlEPTBiPTCxNE43KM7:TT6= M1W3ZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMEO1OVQyLz5|MECzOVU1OTxxYU6=
C13 NV\xS21GS3m2b4TvfIlkcXS7IHHzd4F6 M1izN|czKGi{cx?= NUG5W|lFS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSzF|IHPlcIx{KGGodHXyJFczKGi{czygTWM2OCB;IEGyMlEh|ryPLh?= Mn21QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzByM{W1OFEoRjNyMEO1OVQyRC:jPh?=
HCT8 MYjBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NVm1VZdqPzJiaILz NX3zSoZmSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3Q5KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyPE46KM7:TT6= MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODB|N{S5OEc,OzByM{e0PVQ9N2F-
DLD1 MVTBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NETqRVU4OiCqcoO= M3H5UGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iRFzENUBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iM{Og{txONg>? NI\xcJM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MECzO|Q6PCd-M{CwN|c1QTR:L3G+
CCD-841-CoN MmDlRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MUm3NkBpenN? NEO3W2hCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFPDSE05PDFvQ3;OJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|NT63JO69VS5? MnnRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzByM{e0PVQoRjNyMEO3OFk1RC:jPh?=
SKOV3 NF20NVFEgXSxdH;4bYNqfHliYYPzZZk> M2K1R|Q5KGi{cx?= MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTT29XOyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlYvOzRizszNMi=> M13HXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMEmyN|Y5Lz5|MEC5NlM3QDxxYU6=
HepG2 NVXPV5lrS3m2b4TvfIlkcXS7IHHzd4F6 MlvkOFghcHK| MX\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|EvQThizszNMi=> NXHSfnE5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CwPVI{PjhpPkOwNFkzOzZ6PD;hQi=>
Bel7404 MnTuR5l1d3SxeHnjbZR6KGG|c3H5 Mkn1OFghcHK| MW\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDC[Yw4PDB2IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1OC5{MTFOwG0v MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODB7MkO2PEc,OzByOUKzOlg9N2F-
NCI-H460 MYHDfZRwfG:6aXPpeJkh[XO|YYm= M3nITFQ5KGi{cx?= MnrNR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUmNKNUh2NkCgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR3LkS0JO69VS5? M{C4cVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMEmyN|Y5Lz5|MEC5NlM3QDxxYU6=
RKO MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEXCdnY1QCCqcoO= NUnVZ|BIT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hWkuRIHPlcIx{KGGodHXyJFQ5KGi{czDifUBES0tvODDhd5NigSxiSVO1NEA:KDFyLkKg{txONg>? MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODFyNkK4PUc,OzBzME[yPFk9N2F-
LoVo NVT5cHBHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnvhOFghcHK| NITpeWJIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBNd1[xIHPlcIx{KGGodHXyJFQ5KGi{czDifUBES0tvODDhd5NigSxiSVO1NEA:KDFzLkWg{txONg>? MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODFyNkK4PUc,OzBzME[yPFk9N2F-
MCF7 MlyzRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NInNfWM4OiCqcoO= M1TZc2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMk[uNVQh|ryPLh?= M4LSU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMUSyOlEzLz5|MEG0NlYyOjxxYU6=
MGC803 M{[1WWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 Mnr1O|IhcHK| MXfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2JQ{iwN{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iM{GuNFQh|ryPLh?= NFKzdWY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MEG0NlYyOid-M{CxOFI3OTJ:L3G+
HCT116 NYfXO3l1SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MkiyO|IhcHK| NEPOcHZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFEyPiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|gvOyEQvF2u MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODF2Mk[xNkc,OzBzNEK2NVI9N2F-
HepG2 M37vNmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MWm3NkBpenN? NIqyepBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0O{46PyEQvF2u NXT2cWd7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CxOFI3OTJpPkOwNVQzPjF{PD;hQi=>
A549 NIPQbJJCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MnzDO|IhcHK| MYLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEF3NEmgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJwMEWg{txONg>? MlqzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB{NEOxOVMoRjNyMkSzNVU{RC:jPh?=
Bel7402 M36xbWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MWi3NkBpenN? NG\EOpNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFLlcFc1ODJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE5NjZ3IN88UU4> MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODJ2M{G1N{c,OzB{NEOxOVM9N2F-
MCF7 MYrBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MY[3NkBpenN? NGTCNYJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlch[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEK3Mlg6KM7:TT6= MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODJ2M{G1N{c,OzB{NEOxOVM9N2F-
T84 NHT0dXpCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MVyzJIRigXN? M{fHdWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iVEi0JINmdGy|IHHmeIVzKDNiZHH5d{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBKSzVyIE2gN{41KM7:TT6= NIPNblA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MEK0PFY2Pyd-M{CyOFg3PTd:L3G+
A549 MXvBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M2\k[lMh\GG7cx?= M2LMPGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDh[pRmeiB|IHThfZMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhUUN3MDC9JFcvOSEQvF2u NEXLcJY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MEK0PFY2Pyd-M{CyOFg3PTd:L3G+
MCF7 NVHwUWM5SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MVuzJIRigXN? MWfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhOyCmYYnzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGlEPTBiPTC3Mlgh|ryPLh?= M2P4dVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMkS4OlU4Lz5|MEK0PFY2PzxxYU6=
A549 MXfDfZRwfG:6aXPpeJkh[XO|YYm= M4f1TVczKGi{cx?= MmHPR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOE4{KM7:TT6= NUPTfXlGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CzNVg1PDBpPkOwN|E5PDRyPD;hQi=>
HeLa M3L6Z2N6fG:2b4jpZ4l1gSCjc4PhfS=> NFq5bmU4OiCqcoO= NHm1O3dEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOC55NTFOwG0v NHn3PZU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MEOxPFQ1OCd-M{CzNVg1PDB:L3G+
HCT116 M4T4[2N6fG:2b4jpZ4l1gSCjc4PhfS=> MlruO|IhcHK| M4D6[WN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDFzNjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTFwNU[g{txONg>? MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODNzOES0NEc,OzB|MUi0OFA9N2F-
NCI-H460 MULDfZRwfG:6aXPpeJkh[XO|YYm= MXS3NkBpenN? M1uwcWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KNE[wJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMT63OUDPxE1w Mn7xQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB|MUi0OFAoRjNyM{G4OFQxRC:jPh?=
HCT15 NGrBWVlEgXSxdH;4bYNqfHliYYPzZZk> Mm[yO|IhcHK| NXrucIF[S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUWgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFzLki3JO69VS5? NWjrNmZURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CzNVg1PDBpPkOwN|E5PDRyPD;hQi=>
MDA-MB-231 MkS5R5l1d3SxeHnjbZR6KGG|c3H5 M1f3VFczKGi{cx?= MXTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{MT6wOUDPxE1w MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODNzOES0NEc,OzB|MUi0OFA9N2F-

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
p53 / PUMA / c-PARP; 

PubMed: 25965911     


(A) HCT-116 cells were treated with various doses of 5-FU for 24 hours (B) HCT-116 cells were treated with 200 uM 5-FU, then harvested at different time points after stimulation. The expression of p53, PUMA, cleaved PARP and P-Akt(S473) were detected by western blotting in different conditions.

25965911
Immunofluorescence
caveolin-3; 

PubMed: 23646193     


Cells were stained with an antibody against caveolin-3 (green) and with DAPI (blue). (A) control cells (top images), 10 mM 5-FU (middle images), 50 mM 5-FU (bottom images). Merged images are shown at the right of each panel.

phospho-histone H3 ; 

PubMed: 23646193     


Cells were grown for 24 h, treated with 5-FU and stained with an anti-phospho-histone H3 antibody (red) and with DAPI (blue). (A) control cells, (B) 0.1 mM 5-FU and (C) 1 mM 5-FU. 

p65 / p-p65(Ser536) / p53 / p-p53(Ser15); 

PubMed: 24587255     


E–H, Immunocytochemistry of p65 and p53 induction and localization by 5-FU treatment for the indicated cell lines. p65 (red), phosphor-p65 (Ser536; red), p53 (green), phospho-p53 (Ser15; red), and DAPI (blue) staining of the nucleus without (control) and with 5-FU treatment. 

Sox2 / Oct4 / Nanog / ABCG2; 

PubMed: 27009861     


(A) Immunofluorescence staining of Sox2, Oct4 and Nanog in HBE cells with or without 5-FU treatment. In untreated HBE cells, few Sox2, Oct4 or Nanog-positive cells were observed. After 5-FU treatment, the number of Sox2, Oct4 or Nanog-positive cells increased remarkably. Nuclei were counterstained with DAPI (blue). (B) Immunofluorescence staining of ABCG2 in HBE cells with or without 5-FU treatment. 

β-catenin; 

PubMed: 30111797     


Immunofluorescence detection of β-catenin in HCT-8 cells. Scale bar, 20 μm.

non-phospho β-catenin; 

PubMed: 28588704     


Effect of enhanced WNT signaling in Ell3 OE cells. Localization of non-phosphorylated β-catenin was analyzed by immunocytochemical staining in (A) control MCF-7 and (B) Ell3 OE treated with various 5-FU concentrations.

23646193 24587255 27009861 30111797 28588704
Growth inhibition assay
Cell viability; 

PubMed: 25965911     


Cells viability was analyzed using Cell Counting Kit-8 at 0, 3, 6, 12 and 24 hours after (A) 50, 100, 200, or 400 uM 5-FU treatment in HCT116 cells.

Cell proliferation; 

PubMed: 30250641     


(A) Cell proliferation assay with resveratrol in HCT116. Cells were treated with resveratrol at 0 ~ 200 μM for 72 hours and applied to MTS assay. (B) HCT116 cells were treated with 5-FU at 0~200 μM for 72 hours. (C)HCT116 cells were treated with resveratrol at 0 ~ 200 μM combined with 5-FU at 10 μM for 72 hours and applied to MTS assay. (D) DLD1 cell proliferation assay with resveratrol at 0 ~ 200 μM for 72 hours. (E) DLD1 cells were treated with 5-FU at 0~ 200 μM for 72 hours. (F) DLD1 cells were treated with resveratrol combined with 5-FU at 10 μM for 72 hours. Error bars represent standard deviation.

25965911 30250641
In vivo Adrucil is widely used in the treatment of a range of cancers, including colorectal and breast cancers. [1] 100mg/kg Adrucil significantly suppresses tumor growth of murine colon carcinomas Colon 38 with tumor-doubling time (TD), growth-delay factor (GDF), and T/C of 26.5 days, 4.4, and 14%. [5]

Protocol

Cell Research:[4]
- Collapse
  • Cell lines: Human colon carcinoma cell line HT-29
  • Concentrations: ~25 μM
  • Incubation Time: 7 days
  • Method: Growth inhibition is measured after treatment of cells with Adrucil for 7 days in 96-well plates (4000 HT-29 cells/well in RPMI 1640 medium with 10% dialyzed fetal bovine serum); increasing concentrations of Adrucil are added after allowing for cell attachment overnight. At the end of incubation, cells are rinsed three times with phosphate-buffered saline (pH 7.4), fixed with 10% trichloroacetic acid for 60 min at 4 ℃, washed five times with deionized water, and stained with 0.4% sulforhoda-mine B solution for 15 min at room temperature. Unstained sulforhodamine B is removed by rinsing with 1% glacial acetic acid. Afterwards, stained cell proteins are dried and dissolved with 10 mM Tris-HCl. The optical density value is measured using a detector at 540 nm wavelength.
    (Only for Reference)
Animal Research:[5]
- Collapse
  • Animal Models: Murine colon carcinomas Colon 38
  • Dosages: 100 mg/kg
  • Administration: i.p. weekly
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 26 mg/mL (199.87 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
saline (warming)
For best results, use promptly after mixing.
10mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 130.08
Formula

C4H3FN2O2

CAS No. 51-21-8
Storage powder
in solvent
Synonyms NSC 19893
Smiles C1=C(C(=O)NC(=O)N1)F

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04274790 Not yet recruiting Procedure: Scheduled and planned surgery Cancer of Colon|Metastasis to Liver Centre Leon Berard June 1 2021 --
NCT04825288 Recruiting Biological: XB2001 or Placebo Pancreatic Cancer XBiotech Inc. May 27 2021 Phase 1|Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    I was wondering if the product #s1209 (5-fluorouracil) is suitable to inject into mice ?

  • Answer:

    S1209 is suitable to inject (I.P.) into mice as indicating in this paper: http://www.ncbi.nlm.nih.gov/pubmed/8995503.

DNA/RNA Synthesis Signaling Pathway Map

Related DNA/RNA Synthesis Products

Tags: buy Fluorouracil (5-Fluorouracil, 5-FU) | Fluorouracil (5-Fluorouracil, 5-FU) supplier | purchase Fluorouracil (5-Fluorouracil, 5-FU) | Fluorouracil (5-Fluorouracil, 5-FU) cost | Fluorouracil (5-Fluorouracil, 5-FU) manufacturer | order Fluorouracil (5-Fluorouracil, 5-FU) | Fluorouracil (5-Fluorouracil, 5-FU) distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID