Name: Fluoxetine (Lilly 110140) HCl
Brand: Selleck Chemicals
SKU: S1333
Rating: 5 (16 reviews)

Fluoxetine (Lilly 110140) HCl Chemical Structure

CAS No. 56296-78-7

Selleck's Fluoxetine (Lilly 110140) HCl has been cited by 16 publications

Purity & Quality Control

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5-HT Receptor Signaling Pathway Map

Biological Activity

Description

Fluoxetine HCl (Prozac, Sarafem,LY-110140) is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.

Targets

5-HT ^[1]

In vitro

Fluoxetine blocks the downregulation of cell proliferation resulting from inescapable shock (IS) of hippocampal cell. ^[1] Fluoxetine increases the number of newborn cells in the dentate gyrus of the hippocampus of adult rat. Fluoxetine also increases the number of proliferating cells in the prelimbic cortex. ^[2] Fluoxetine accelerates the maturation of immature neurons. Fluoxetine enhances neurogenesis-dependent long-term potentiation (LTP) in the dentate gyrus. ^[3] Fluoxetine, but not citalopram, fluvoxamine, paroxetine and sertraline, increases norepinephrine and dopamine extracellular levels in prefrontal cortex. Fluoxetine produces robust and sustained increases in extracellular concentrations of norepinephrine and dopamine after acute systemic administration. ^[4]

Cell Data

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

HEK293	MlPDSpVv[3Srb36gZZN{[Xl?	NX\k[oVZOzBibXnudy=>	NHy4U5BKdmirYnn0bY9vKG:oIHj1cYFvKFOHUmSg[ZhxemW\|c3XkJIlvKEiHS{K5N{Bk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIIPldo91d26rbjDy[ZVxfGGtZTDh[pRmeiB\|MDDtbY5{KGK7IH\seY9z\XOlZX7j[UBie3OjeTygTWM2OD1yLkG1{txO	NXPRc5hXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5N\|gxPDlpPkKyPVM5ODR7PD;hQi=>
HEK293	M4XrVGZ2dmO2aX;uJIF{e2G7	MWizNEBucW6\|	M1yzS2lvcGmkaYTpc44hd2ZiaIXtZY4hVkWWIHX4dJJme3OnZDDpckBJTUt{OUOgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iCwb4Lh[JJmdmGuaX7lJJJmfXC2YXvlJIFnfGW{IEOwJI1qdnNiYomg[ox2d3Knc3PlcoNmKGG\|c3H5MEBKSzVyPUSuOFHPxE1?	M2PQ[\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OUO4NFQ6Lz5{MkmzPFA1QTxxYU6=
HEK293	MnTISpVv[3Srb36gZZN{[Xl?	M4HYflMxKG2rboO=	M{HVbmlvcGmkaYTpc44hd2ZiaIXtZY4hTEGWIHX4dJJme3OnZDDpckBJTUt{OUOgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iCmb4DhcYlv\SC{ZYXweIFs\SCjZoTldkA{OCCvaX7zJIJ6KG[udX;y[ZNk\W6lZTDhd5NigSxiSVO1NF0yQC52zszN	NVTNepFDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5N\|gxPDlpPkKyPVM5ODR7PD;hQi=>
mammalian cells	M3rrXmZ2dmO2aX;uJIF{e2G7		MVfJcohq[mm2aX;uJI9nKGi3bXHuJHBwfGG\|c3n1cUBkcGGwbnXsJGhGWkdiZYjwdoV{e2WmIHnuJI1idW2jbHnhckBk\WyuczygTWM2OD1zLkWxN\|U3\|ryP	M1fr[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{OEezOVEzLz5zMki3N\|UyOjxxYU6=
JAR	NILkPFBHfW6ldHnvckBie3OjeR?=		MVnJcohq[mm2aX;uJINwdmOnboTyZZRqd25iYXfhbY5{fCCdM1jdOU1JXCC3cIThb4Uh[nliaIXtZY4he2W{b4TvcolvKHS{YX7zdI9zfGW{IHnuJGpCWiClZXzsd{whUUN3ME2wMlA{OjUQvF2=	NXSxbIl3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWyN\|k3PjFpPkG1NlM6PjZzPD;hQi=>
K562	MUPDfZRwfG:6aXPpeJkh[XO\|YYm=		NYDxUlIyS3m2b4TvfIlkcXS7IITvJJJm\HWlZTDjbJJwdmmlIH35[YxwcWRibHX1b4VucWFiSzC1OlIh[2WubIOsJGNEPTB;MkZOwG0>	MkDKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV{NkeyNlkoRjF3Mk[3NlI6RC:jPh?=
U937	MVnDfZRwfG:6aXPpeJkh[XO\|YYm=		MknrR5l1d3SxeHnjbZR6KHSxIILl[JVk\SCqdX3hckBpcXO2b3z5eIlkKGy7bYDoc41iKFV7M{egZ4VtdHNuIFPDOVA:OzNwM988US=>	MlfjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV{NkeyNlkoRjF3Mk[3NlI6RC:jPh?=
HEK293	NFnpSoFHfW6ldHnvckBie3OjeR?=		M2DLXWlvcGmkaYTpc44hd2ZiW{PIYVUuUFRidYD0ZYtmKGG2IEXIWEB1emGwc4DvdpRmeiCneIDy[ZN{\WRiaX6gTGVMOjl\|IHPlcIx{NCCLQ{WwQVAvODF4zszN	NVPRNo1ERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[3OVA{PTlpPkG2O\|UxOzV7PD;hQi=>
HEK293	NH3qR4tHfW6ldHnvckBie3OjeR?=		NInqZ\|dKdmirYnn0bY9vKG:oIFTBJJRz[W6\|cH;yeIVzKGW6cILld5Nm\CCrbjDISWszQTNiY3XscJMtKEmFNUC9OE41\|ryP	MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjd3MEO1PUc,OTZ5NUCzOVk9N2F-
HEK293	Ml3DSpVv[3Srb36gZZN{[Xl?		MljvTY5pcWKrdHnvckBw\iCdM1jdUmEhfXC2YXvlJIF1KE6DIITyZY5{eG:{dHXyJIV5eHKnc4Pl[EBqdiCKRVuyPVMh[2WubIOsJGlEPTB;NT6y{txO	NUHENI5JRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[3OVA{PTlpPkG2O\|UxOzV7PD;hQi=>
HEK293	NHi0foxHfW6ldHnvckBie3OjeR?=		MorzTY5pcWKrdHnvckBw\iCdM1jdOU1JXCC{ZYXweIFs\SCjdDC1THQhfHKjboPwc5J1\XJiaX6gTGVMOjl\|IHPlcIx{NCCLQ{WwQVAvODF4zszN	M1jhZ\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4N{WwN\|Y{Lz5zNke1NFM3OzxxYU6=
HEK293	MnrRSpVv[3Srb36gZZN{[Xl?		M4nsNGlvcGmkaYTpc44hd2ZiW{PIYWRCKHKndYD0ZYtmKGG2IFTBJJRz[W6\|cH;yeIVzKGmwIFjFT\|I6OyClZXzsd{whUUN3ME20MlTPxE1?	MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjd3MEO2N{c,OTZ5NUCzOlM9N2F-
HEK293	M1;rb2Z2dmO2aX;uJIF{e2G7		MkWwTY5pcWKrdHnvckBw\iCdM1jdUmEhemW3cIThb4Uh[XRiTlGgeJJidnOyb4L0[ZIhcW5iSFXLNlk{KGOnbHzzMEBKSzVyPUWuNu69VQ>?	NWHiV4ZURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[3OVA{PjNpPkG2O\|UxOzZ\|PD;hQi=>
Jar	NFXjVo5HfW6ldHnvckBie3OjeR?=		NHjvUHRKdmirYnn0bY9vKG:oIGuzTH02NUiWIIXweIFs\SCjdDDoeY1idiB3LVjUJJRz[W6\|cH;yeIVzKGW6cILld5Nm\CCrbjDKZZIh[2WubIOsJGlEPTB;MD6wN\|k1\|ryP	NUiyeFJlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[4OVQxQDZpPkG2PFU1ODh4PD;hQi=>
SK-N-MC	NWHrTWlMTnWwY4Tpc44h[XO\|YYm=		MWDEbZNxdGGlZX3lcpQhd2ZiTj3bN2he[WyyaHGtcYV1cHmuaHnzeIFucW6nIH\yc40hcHWvYX6gbIl{fGGvaX7lJGg{KHKnY3XweI9zKGW6cILld5Nm\CCrbjDTT{1PNU2FIHPlcIx{NCCNaU23MlPPxE1?	NHrqSo09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{OwO\|M2QCd-MUezNFc{PTh:L3G+
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HEK293	NETyd4xHfW6ldHnvckBie3OjeR?=		NFvC[45KdmirYnn0bY9vKG:oIIPldo91d26rbjD1dJRic2ViYYSgbJVu[W5iU1XSWEBqdiCqdX3hckBJTUt{OUOgZ4VtdHNuIFnDOVA:OC5yNEhOwG0>	MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDV3MEO2PUc,OTh3NUCzOlk9N2F-
HEK293	Mk\sSpVv[3Srb36gZZN{[Xl?		MnnrTY5pcWKrdHnvckBw\iCwb4LldIlv\XCqcnnu[UB2eHSja3WgZZQhcHWvYX6gUmVVKGmwIHj1cYFvKEiHS{K5N{Bk\WyuczygTWM2OD1{zszN	NH7pXog9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEW1NFM3QSd-MUi1OVA{Pjl:L3G+
HEK293	NX30b2xRTnWwY4Tpc44h[XO\|YYm=		MVXJcohq[mm2aX;uJI9nKGSxcHHtbY5mKHWydHHr[UBifCCqdX3hckBFSVRiaX6gbJVu[W5iSFXLNlk{KGOnbHzzMEBKSzVyPUdOwG0>	NV\4NlFnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1OVA{PjlpPkG4OVUxOzZ7PD;hQi=>
JAR	NU\5No4{TnWwY4Tpc44h[XO\|YYm=		NI\3U\|dKdmirYnn0bY9vKG:oIEXIWEB2eHSja3WgZZQhcHWvYX6gV2VTXCCneIDy[ZN{\WRiaX6gbJVu[W5iSlHSJINmdGy\|LDDJR\|UxRTBwMEC5OO69VQ>?	NHftUpg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEW1O\|YxQCd-MUi1OVc3ODh:L3G+
HEK	NF3yeWFHfW6ldHnvckBie3OjeR?=		NH;JVIdKdmirYnn0bY9vKG:oIIPldo91d26rbjD1dJRic2ViYYSgbJVu[W5iU1XSWEBmgHC{ZYPz[YQhcW5iSFXLJINmdGy\|LDDJR\|UxRTBwMES3{txO	NFu1Zos9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOE[2O\|MxQSd-MUi2Olc{ODl:L3G+
HEK	NVXRPIR7TnWwY4Tpc44h[XO\|YYm=		NFHEcXBKdmirYnn0bY9vKG:oIH7vdoVxcW6ncHjybY5mKHWydHHr[UBifCCqdX3hckBPTVRiZYjwdoV{e2WmIHnuJGhGUyClZXzsd{whUUN3ME2y{txO	M{LJXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6Nk[3N\|A6Lz5zOE[2O\|MxQTxxYU6=
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Jar	NVq5NlRMTnWwY4Tpc44h[XO\|YYm=		MlfETY5pcWKrdHnvckBw\iB3LVjUJJRz[W6\|cH;yeIVzNW2nZHnheIVlKFt\|SG21THQhfXC2YXvlJIlvKGi3bXHuJGpieiClZXzsd{whUUN3ME2wMlA{QTUQvF2=	NWPuZ45SRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi4N\|QyQDhpPkG4PFM1OTh6PD;hQi=>
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HEK293	M2jpTGZ2dmO2aX;uJIF{e2G7		NX\6SHlkUW6qaXLpeIlwdiCxZjDbN2heVkViZoLvcUBpfW2jbjDy[YNwdWKrbnHueEBPTVRiZYjwdoV{e2WmIHnuJGhGUzJ7MzDj[YxteyxiSVO1NF0yNjB{zszN	NWjEd4NYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwNVQ5QDhpPkG5NFE1QDh6PD;hQi=>
HEK293	NIG1e5ZHfW6ldHnvckBie3OjeR?=		MXHEbZNxdGGlZX3lcpQhd2ZiW{GyOWleWlSLNUWg[pJwdSCqdX3hckBz\WOxbXLpcoFvfCCQRWSg[ZhxemW\|c3XkJIlvKEiHS{K5N{Bk\WyuczygT4k:OS53Nt88US=>	MmLBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyMUS4PFgoRjF7MEG0PFg5RC:jPh?=
HEK293	NV\5U5MzTnWwY4Tpc44h[XO\|YYm=		M4riR2Rqe3CuYXPlcYVvfCCxZjDbNVI2UV2UVFm1OUBnem:vIHj1cYFvKHKnY3;tZolv[W62IFTBWEBmgHC{ZYPz[YQhcW5iSFXLNlk{KGOnbHzzMEBMcT14Lk[3{txO	MoTpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyMUS4PFgoRjF7MEG0PFg5RC:jPh?=
HEK293	NETqVVlHfW6ldHnvckBie3OjeR?=		NVzSblNxUW6qaXLpeIlwdiCxZjDbN2heTEFiZoLvcUBpfW2jbjDy[YNwdWKrbnHueEBFSVRiZYjwdoV{e2WmIHnuJGhGUzJ7MzDj[YxteyxiSVO1NF0yQS53zszN	NIPRRlc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUCxOFg5QCd-MUmwNVQ5QDh:L3G+
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HEK293	NVnER2FDTnWwY4Tpc44h[XO\|YYm=	NEXIc2oyPSCvaX7z	NYTYfph4UW6qaXLpeIlwdiCxZjDoeY1idiCQRWSg[ZhxemW\|c3XkJIlvKEiHS{K5N{Bk\WyuczDheEBqdmO3YnH0[YQh\m:{IEG1JI1qdnNiYomgcoV2em:2cnHud41qfHSncjDy[ZVxfGGtZTDhd5NigSxiSVO1NF01NjRzzszN	M2nFZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MkKxOlU3Lz5{NUKyNVY2PjxxYU6=
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HEK293	NULYb2lnTnWwY4Tpc44h[XO\|YYm=		NYPye\|d5UW6qaXLpeIlwdiCxZjDv[kBpfW2jbjDUVmVMOSCneIDy[ZN{\WRiaX6gTGVMOjl\|IHPlcIx{KGG\|c3Xzd4VlKGG\|IILl[JVkfGmxbjDpckBkcGGwbnXsJIN2enKnboTzMEBKSzVyPUG0{txO	Mo\6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ3OEiwOFUoRjJ4NUi4NFQ2RC:jPh?=
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OHS-50	M{GyWpFJXFNiYYPzZZk>		M13lVJFJXFNib3[gdIVlcWG2cnnjJINidmOncjDj[YxtKGyrbnXzJJRwKGmmZX70bYZ6KG23bITpdIxmKG:ycH;yeJVvcXSrZYOg[o9zKGS{dXegdoVxfXKyb4Ppcoc7KFC{aX3hdpkhe2O{ZXXuJIZweiCRSGOtOVAh[2WubIO=	NUDRb4dTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N\|UyOzlpPkK5OFM2OTN7PD;hQi=>
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RD	M3vIWGFvfGm4aYLhcEBie3OjeR?=	NFzPNmE2KG2rboO=	NX7qe4M2SW62aY\pdoFtKGGldHn2bZR6KGGpYXnud5QhTW62ZYLveolzfXNiRE[4JHVUN0u\L{G0MVE5QTV\|IHnu[oVkfGWmIHnuJIh2dWGwIGLEJINmdGy\|IHHzd4V{e2WmIHHzJIlvcGmkaYTpc44hd2ZidnnyeZMucW6mdXPl[EBkgXSxcHH0bIlkKGWoZnXjeEBqdmO3YnH0[YQh\m:{IEWgcYlveyC3bnTldkB{cGGtaX7nJINwdmSrdHnvckBidmRibXXhd5Vz\WRiYX\0[ZIhOyCmYYnzJIJ6KG6ndYTyZYwhemWmIHT5[U1j[XOnZDDwbI91d22ndILpZ{Bu\XSqLDDFR\|UxRTIQvF2=	Ml;zQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB7MUK5OFQoRjNyOUGyPVQ1RC:jPh?=
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Huh7	M4TTUmFvfGm4aYLhcEBie3OjeR?=		MVnBcpRqfmm{YXygZYN1cX[rdImgZYdicW6\|dDDESW5XOiCrbn\lZ5Rm\CCrbjDoeY1idiCKdXi3JINmdGy\|IHL5JJFTXC2SQ2KgZY5idHm\|aYOsJGlEPTB;MD6zPO69VQ>?	NVnGfGZ[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{GxNlg1PDdpPkOxNVI5PDR5PD;hQi=>

Click to View More Cell Line Experimental Data

In vivo

Fluoxetine treatment also reverses the deficit in escape latency observed in animals exposed to inescapable shock in adult male Sprague–Dawley rats. ^[1] Fluoxetine combined with Olanzapine produces robust, sustained increases of extracellular levels of dopamine ([DA](ex)) and norepinephrine ([NE](ex)) up to 361% and 272% of the baseline, respectively, which are significantly greater than either drug alone. ^[5]

Protocol (from reference)

References

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Solubility (25°C)

In vitro

Chemical Information

Molecular Weight	345.79
Formula	C₁₇H₁₈F₃NO.HCl
CAS No.	56296-78-7
Storage	3 years	-20°C	powder
Storage	2 years	-80°C	in solvent
Smiles	CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.Cl

Download Fluoxetine (Lilly 110140) HCl SDF

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Dilution Calculator Molecular Weight Calculator

Clinical Trial Information

NCT Number	Recruitment	Interventions	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT04676139	Recruiting	Drug: Fluoxetine\|Drug: Placebo	Nocturnal Enuresis	Mansoura University	July 1 2020	Phase 3
NCT01615055	Withdrawn	Drug: Fluoxetine\|Other: Placebo	Cognitive Dysfunction	University of California Los Angeles\|City of Hope Medical Center	June 2018	Early Phase 1
NCT03390933	Recruiting	Drug: Fluoxetine	Depression\|Hemodialysis-Induced Symptom	MetroHealth Medical Center	March 1 2018	Phase 4
NCT02767999	Unknown status	Drug: Fluoxetine\|Drug: Placebo\|Radiation: fMRI	Stroke	University Hospital Toulouse	February 27 2017	Phase 4
NCT03476525	Recruiting	Drug: Fluoxetine	Obesity Morbid	Norwegian University of Science and Technology\|St. Olavs Hospital\|Volvat Medisinsk Senter Stokkan\|Namsos Hospital\|Alesund Hospital	November 2 2016	--

(data from https://clinicaltrials.gov, updated on 2022-11-29)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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