Home Microbiology Bacterial chemical Fosfomycin Disodium

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Fosfomycin Disodium Bacterial chemical

Cat.No.S5048

Fosfomycin (Phosphonemycin) is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis.
Fosfomycin Disodium Bacterial chemical Chemical Structure

Chemical Structure

Molecular Weight: 182.02

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Quality Control

Batch: S504801 Water]36 mg/mL]false]DMSO]Insoluble]false]]]false Purity: 98%
98

Solubility

In vitro
Batch:

Water : 36 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

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In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 182.02 Formula

C3H5O4P.2Na

 Storage (From the date of receipt)
CAS No. 26016-99-9 -- Storage of Stock Solutions

Synonyms Phosphonemycin Disodium SMILES CC1C(O1)P(=O)([O-])[O-].[Na+].[Na+]

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-06-12)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06822751 NOT_YET_RECRUITING
Urinary Tract Infection; Prostatitis; Cystitis
University Hospital, Rouen
 2026-07 PHASE3
NCT07004049 RECRUITING
Bloodstream Infection; Ventilator Associated Bacterial Pneumonia; Hospital Acquired Bacterial Pneumonia; Carbapenem Resistant Bacterial Infection; Multidrug Resistance
National University of Singapore
 2025-04-21 PHASE4
NCT07618299 NOT_YET_RECRUITING
Healthy Lactating Women
Meitheal Pharmaceuticals, Inc.
 2026-07 PHASE4
NCT05709028 RECRUITING
Urinary Tract Infections
University of Sydney
 2023-08-02 PHASE3
NCT07557901 ENROLLING_BY_INVITATION
Infectious Complications Following Prostate Biopsy; Prostate Cancer
F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica
 2026-04-01
NCT07063095 RECRUITING
Gram Negative Infections; Sepsis and Septic Shock
Angela HUTTNER
 2025-08-25 PHASE3

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