Floxuridine

For research use only.

Catalog No.S1299 Synonyms: Deoxyfluorouridine, FUDR, NSC 27640

5 publications

Floxuridine Chemical Structure

CAS No. 50-91-9

Floxuridine (Deoxyfluorouridine, FUDR, NSC 27640) is a prodrug that is rapidly catabolized to 5-fluorouracil in vivo. Floxuridine is used to treat various cancers, particularly metastases to the liver. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage and apoptosis. Floxuridine has antiviral effects against HSV and CMV.

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Selleck's Floxuridine has been cited by 5 publications

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description Floxuridine (Deoxyfluorouridine, FUDR, NSC 27640) is a prodrug that is rapidly catabolized to 5-fluorouracil in vivo. Floxuridine is used to treat various cancers, particularly metastases to the liver. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage and apoptosis. Floxuridine has antiviral effects against HSV and CMV.
In vitro

Floxuridine exhibits higher affinity for PEPT1 than the corresponding 5'-O-mono amino acid ester prodrugs. [1] Floxuridine combined with Leucovorin results in synergistic inhibitory effects on growth of human T-lymphoblast leukemia cells. [2] Floxuridine significantly inhibits the uptake of both [(3)H]-inosine and [(3)H]-adenosine (60-70% of control), while its amino acid ester prodrugs including Val, Phe, Pro, Asp, and Lys esters exhibits markedly decreased inhibition potency (10-30% of control). [3] Floxuridine inhibits cell proliferation by more than 50% relative to the untreated control cells at 36 days, the cell numbers still increases fourfold compared with the initial cell density. Floxuridine results in prolonged effects on the proliferation of human Tenon's capsule fibroblasts in vitro. [4] Floxuridine (FUDR) is an ideal drug for hepatic arterial infusion (HAI) due to its short half life, steep dose response curve, high total body clearance, and high hepatic extraction. [5]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
CCRF-CEM cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NELTOJVV\XO2ZXSgbY4hfmm2cn:g[o9zKHSqZTDpcohq[mm2aX;uJI9nKGOnbHyg[5Jwf3SqIH;mJIh2dWGwIGSgcJlueGixYnzhd5RwcWRiQ1PSSk1ETU1iY3XscEBtcW6nIDjBWGNEKEOFTDCxNVkqNCCLQ{WwQVAvPSEQvF2= MYmxNVkxQTdzNh?=
CCRF-CEM NY\SRXVPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2rmTGlvKH[rdILvJINwdmOnboTyZZRqd25icnXxeYlz\WRiZn;yJFUxLSCrbnjpZol1cW:wIH;mJIdzd3e2aDDv[kBpfW2jbjDs[ZVs\W2rYTDj[YxtKGyrbnWgR2NTTi2FRV2ge4l1cCCqUFHQJEgxNjJidX7peE9uVCluIFfJOVA:OC5yMEC2JO69VQ>? NVy5TmRIOTF3OUe0NFQ>
LNCaP cells M1[yNWN6fG:2b4jpZ4l1gSCjc4PhfS=> NYLGemdDS3m2b4TvfIlkKGOxbnPlcpRz[XSrb36gbY4heHKxc4TheIUhe3CnY3nmbYMh[W62aXflckApWFODKTDwdo9lfWOrbnegbJVu[W5iTF7DZXAh[2WubIOsJGlEPTB;MD6wOlkzKM7:TR?= NYHGZox[OTJzNkGxOVc>
TSU cells Ml3ER5l1d3SxeHnjbZR6KGG|c3H5 MVrDfZRwfG:6aXOgZ49v[2WwdILheIlwdiCrbjDuc44heHKxc4TheIUhe3CnY3nmbYMh[W62aXflckApWFODKTDwdo9lfWOrbnegbJVu[W5iVGPVJINmdGy|LDDJR|UxRTBwMEW4JO69VQ>? M{HMVVEzOTZzMUW3
KBALB cell NWHDe4FsS3m2b4TvfIlkcXS7IHHzd4F6 M1fqSWlvKH[rdILvJINmdGxiY4n0c5RwgGmlaYT5JIFo[Wmwc4SgT2JCVEJiY3XscEBtcW6nIDj0doFve2[xcn3l[EBncWK{b3LsZZN1KHOjcnPvcYEh[2WubDDsbY5mMSxiQ1O1NF03NjByRT2wOUDPxE1? M2XrdlEzPjJyMEe2
KBALB-STK cell MYfDfZRwfG:6aXPpeJkh[XO|YYm= MmK2TY4hfmm2cn:gZ4VtdCCleYTveI95cWOrdImgZYdicW6|dDDLRmFNSi2VVFugZ4VtdCCuaX7ld{BmgHC{ZYPz[YQhcW5iSGPWMVEhXEtuIFnDOVA:QC56MFWtNFUh|ryP MXWxNlYzODB5Nh?=
L1210 mouse leukemia cells NXv5dIpiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3XVTFI1KGh? NVTuSHlxT3Kxd4ToJIlvcGmkaYTpc44hcW5iTEGyNVAhdW:3c3WgcIV2c2WvaXGgZ4VtdHNiYX\0[ZIhOjRiaDD0doVifG2nboSsJGlEPTB;MD6wNFQyKM7:TR?= MYSxNVczQDF7Mx?=
L1210 mouse leukemia cells MkHyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2WyZlQ5KGh? MUfHdo94fGhiaX7obYJqfGmxbjDpckBNOTJzMDDtc5V{\SCuZYXr[Y1q[SClZXzsd{Bi\nSncjC0PEBpeiC2cnXheI1mdnRuIFnDOVA:OC5yMEC2OEDPxE1? MoXvNVE4OjhzOUO=
L5178Y cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnLYR49ueGG{YYTpeoUhcW6qaXLpeIlwdiCxZjDMOVE4QFliY3XscEBoem:5dHigbY4hfmm2cn:gLINwdmOnboTyZZRqd25icnXxeYlz\WRiZn;yJFUxLSCrbnjpZol1cW:wKTygTWM2OD1yLkCwNFc3KM7:TR?= MlfzOlc4QTByNx?=
L5178Y cells NEjCcYhHfW6ldHnvckBie3OjeR?= NHrBfXFKdmirYnn0c5J6KGOxbnPlcpRz[XSrb36gc4Yh[2:vcH;1coQhf2G|IHPhcIN2dGG2ZXSgc44hVDVzN{jZJINmdGy|IHL5JHsyPEOfTHX1JIlv[2:{cH;yZZRqd25uIFnDOVA:OiEQvF2= NF6zWHE5OjR4MkK5
L1210 mouse leukemia cells NXHpfGRoTnWwY4Tpc44h[XO|YYm= MXeyJIg> NVK4VWVJXGi7bXnkfYxifGVic4nueIhie2ViaX7obYJqfGmxbjDpckBNOTJzMDDtc5V{\SCuZYXr[Y1q[SClZXzsd{Bi\nSncjCyJIhzKHS{ZXH0cYVvfCxiSVO1NF0xNjByN{mg{txO MUexNVczQDF7Mx?=
LM cells MWrGeY5kfGmxbjDhd5NigQ>? MX6yJIg> NVj6eoZ1XGi7bXnkfYxifGVic4nueIhie2ViaX7obYJqfGmxbjDpckB1cHmvaXTpcoUhc2mwYYPlJIRm\mmlaXXueEBNVSClZXzsd{Bi\nSncjCyJIhzKHS{ZXH0cYVvfCxiSVO1NF02NjRizszN NXr2VlYxOTF5MkixPVM>
HT1080 cells MYjGeY5kfGmxbjDhd5NigQ>? MXHDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSGSxNFgxKGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NF0xNjF6IN88US=> Mk\mNVc5ODR{M{G=
L1210 cells M2jOTmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYS2UXhtPzJiaB?= MlzxR5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JI1wfXOnIFyxNlExKGOnbHzzJGFVS0NiQ1PMNlE6KGG|c3Xzd4VlKGG|IHfyc5d1cCC{ZXT1Z5Rqd25iYX\0[ZIhPzJiaILzMEBKSzVyPUCuNFEzKM7:TR?= MmCyNVc6QTd|MUm=
HL60 cells MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYq3NkBp Mkm0R5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjMOlAh[2WubIOgRXRESyCFQ1ygNlQxKGG|c3Xzd4VlKGG|IHfyc5d1cCC{ZXT1Z5Rqd25iYX\0[ZIhPzJiaILzMEBKSzVyPUCuNFEzKM7:TR?= M3fxfFE4QTl5M{G5
CCRF-CEM cells MnjlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3;ybFczKGh? NHjYXIlEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gR2NTTi2FRV2gZ4VtdHNiQWTDR{BES0xiMUG5JIF{e2W|c3XkJIF{KGe{b4f0bEBz\WS3Y4Tpc44h[W[2ZYKgO|IhcHK|LDDJR|UxRTBwMEG3JO69VQ>? NV;YSJpmOTd7OUezNVk>
L1210 cells NUDleZJ3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3rX[|czKGh? NXHlUYhIS3m2b4P0ZZRq[yCjY4Tpeol1gSCrbjDtc5V{\SCOMUKxNEBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIHPlcIwh\3Kxd4ToJIFnfGW{IEeyJIhzeyxiSVO1NF0xNjBzMjFOwG0> NY[5NXA4OThyN{i3OVc>
HL60 cells NFHmW3NIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXjKNWl{PzJiaB?= M1rQfGN6fG:|dHH0bYMh[WO2aY\peJkhcW5iaIXtZY4hUEx4MDDj[YxteyCjc4Pld5Nm\CCjczDpcohq[mm2aX;uJI9nKGOnbHyg[5Jwf3SqIHHmeIVzKDd{IHjyd{whUUN3ME2wMlAyOiEQvF2= NXrlW|BmOThyN{i3OVc>
CCRF-CEM cells M1zNRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4HrXFczKGh? M1zLeGN6fG:|dHH0bYMh[WO2aY\peJkhcW5iaIXtZY4hS0OURj3DSW0h[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDj[YxtKGe{b4f0bEBi\nSncjC3NkBpenNuIFnDOVA:OC5yMUeg{txO M4rOUVE5ODd6N{W3
CCRF-CEM cells M{j5UWZ2dmO2aX;uJIF{e2G7 NIPnRZo1QCCq MXnBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1PSSk1ETU1iY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5yME[zNUDPxE1? NH;VbmYyQTd2NEi1PC=>
K562 cells Ml3xSpVv[3Srb36gZZN{[Xl? MU[0PEBp Mn;zRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFu1OlIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE44QTR|MzFOwG0> M1zKTFE6PzR2OEW4
MOLT4 cells Mk\lSpVv[3Srb36gZZN{[Xl? MXq0PEBp MkjIRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3PUHQ1KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvODN7OEGg{txO MWOxPVc1PDh3OB?=
RPMI8266 cells MlvaSpVv[3Srb36gZZN{[Xl? Ml3IOFghcA>? MorWRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGLQUWk5OjZ4IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwN{m0N|Mh|ryP MWmxPVc1PDh3OB?=
human SR cells NX;VNplKTnWwY4Tpc44h[XO|YYm= M3zYPVQ5KGh? MVrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MD6wNVI2QSEQvF2= MmnZNVk4PDR6NUi=
A549 cells MnezSpVv[3Srb36gZZN{[Xl? NGrZOHI1QCCq NHS3cFRCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjBzMkW5JO69VQ>? MkHDNVk4PDR6NUi=
EKVX cells NXzVXmdITnWwY4Tpc44h[XO|YYm= MmfoOFghcA>? NXTMco1iSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGVMXlhiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OTBizszN MmrENVk4PDR6NUi=
HOP62 cells MmXSSpVv[3Srb36gZZN{[Xl? NILnPGU1QCCq NUjGbo9nSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhQWDZ{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEK1NVIh|ryP MV[xPVc1PDh3OB?=
HOP92 cells MkW1SpVv[3Srb36gZZN{[Xl? Mmj2OFghcA>? MlPmRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjPVFkzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvPzl2M{Og{txO NYTVXFN{OTl5NES4OVg>
NCI-H226 cells MkD6SpVv[3Srb36gZZN{[Xl? NEX4RW81QCCq MUPBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWgzOjZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[Xl? MYCxPVc1PDh3OB?=
NCI-H23 NIjVPFhHfW6ldHnvckBie3OjeR?= NEXVVIY1QCCq NYSxdnRKSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KMkOgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MUCg{txO NGT4[YcyQTd2NEi1PC=>
NCI-H322 MX3GeY5kfGmxbjDhd5NigQ>? NUXDOZF5PDhiaB?= NHLzXmxCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUmNKNUh|MkLNJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUCuOVAyOTlizszN NYrJ[2pNOTl5NES4OVg>
NCI-H460 MXXGeY5kfGmxbjDhd5NigQ>? NUi5R3ZIPDhiaB?= MYfBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWg1PjBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC53MEGxPUDPxE1? MoHMNVk4PDR6NUi=
NCI-H522 MlHESpVv[3Srb36gZZN{[Xl? M4PFelQ5KGh? NF76WotCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUmNKNUh3MkKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MD6wNFIh|ryP NFKwNZcyQTd2NEi1PC=>
COLO205 cells Ml6zSpVv[3Srb36gZZN{[Xl? M2e5XFQ5KGh? NFq4ZmRCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gR29NVzJyNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1{LkWxNVg6KM7:TR?= NX;hfHpNOTl5NES4OVg>
HCC2998 cells NV;Z[4FDTnWwY4Tpc44h[XO|YYm= MmTPOFghcA>? NF:4d3BCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGNEOjl7ODDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1zLkW4OFg6KM7:TR?= M3LreFE6PzR2OEW4
HCT116 cells NEL5WldHfW6ldHnvckBie3OjeR?= MWm0PEBp NFvrbIRCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMECxJO69VQ>? M4C3WVE6PzR2OEW4
HCT15 cells NX65SHRPTnWwY4Tpc44h[XO|YYm= NGnzNmE1QCCq NHqzR4xCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGNVOTViY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5zMkW4PUDPxE1? MYCxPVc1PDh3OB?=
HT-29 cells NYDl[3VxTnWwY4Tpc44h[XO|YYm= M1iwT|Q5KGh? NVnZb2ZuSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhVNTJ7IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFwOUm1NlYh|ryP M4jkSlE6PzR2OEW4
KM12 cells NFe5e4NHfW6ldHnvckBie3OjeR?= M4LwW|Q5KGh? NIXpW21CdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gT20yOiClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0zNjVzMUi5JO69VQ>? NHz4cYUyQTd2NEi1PC=>
SW620 cells MX\GeY5kfGmxbjDhd5NigQ>? M4HTV|Q5KGh? MYHBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2e2NlAh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9Ok4{ODl3NzFOwG0> MYmxPVc1PDh3OB?=
SF268 cells NXzDfpo2TnWwY4Tpc44h[XO|YYm= MkLyOFghcA>? M4mxVmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTSlI3QCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0yOCEQvF2= MUmxPVc1PDh3OB?=
SF295 cells NXjkbmx6TnWwY4Tpc44h[XO|YYm= NYqyc5ZzPDhiaB?= M2[1UWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTSlI6PSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjBzMkW5JO69VQ>? MVWxPVc1PDh3OB?=
SF539 cells MVLGeY5kfGmxbjDhd5NigQ>? NF;OSVg1QCCq Ml3URY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPGOVM6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvODN7OEGg{txO NUTLT|ZyOTl5NES4OVg>
SNB19 cells M{PGeGZ2dmO2aX;uJIF{e2G7 NVfjVItvPDhiaB?= M3;kT2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTUmIyQSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0yNjl7NUK2JO69VQ>? NUDkeVk5OTl5NES4OVg>
SNB75 cells M{L3SWZ2dmO2aX;uJIF{e2G7 MW[0PEBp MWPBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU17CO|Uh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4yQTl3MzFOwG0> MUSxPVc1PDh3OB?=
U251 cells MXvGeY5kfGmxbjDhd5NigQ>? MkW4OFghcA>? M3uyPGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDVNlUyKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvOTJ3OEmg{txO NXnvZm5NOTl5NES4OVg>
LOXIMVI cells NH;a[49HfW6ldHnvckBie3OjeR?= Mnn4OFghcA>? NXTEb2J3SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGxQYEmPVlmgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MD6wNlUyOiEQvF2= MXSxPVc1PDh3OB?=
MALME-3M cells NIr0NIpHfW6ldHnvckBie3OjeR?= M3nLXFQ5KGh? NV3v[WNOSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1CVE2HLUPNJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUeuPVQ{OjhizszN NETzXmUyQTd2NEi1PC=>
M14 cells MVzGeY5kfGmxbjDhd5NigQ>? NX6xS45LPDhiaB?= MkDqRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF2xOEBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2wMlE2QDR7IN88US=> M3ywbFE6PzR2OEW4
SK-MEL-2 cells MYjGeY5kfGmxbjDhd5NigQ>? M3nNfVQ5KGh? MUnBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU1utUWVNNTJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OTBizszN M1K5[lE6PzR2OEW4
SK-MEL-28 cells Ml7pSpVv[3Srb36gZZN{[Xl? NGLKcFQ1QCCq MmDQRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPLMW1GVC1{ODDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1zLkm5OVI3KM7:TR?= NYDXXmI4OTl5NES4OVg>
SK-MEL-5 cells MnjqSpVv[3Srb36gZZN{[Xl? NHXXU4c1QCCq MWrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU1utUWVNNTViY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5zOUm1N{DPxE1? NVrBTHNNOTl5NES4OVg>
UACC257 cells MU\GeY5kfGmxbjDhd5NigQ>? MYS0PEBp MXjBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iVVHDR|I2PyClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0{NjF4MkK4JO69VQ>? MUKxPVc1PDh3OB?=
UACC62 cells MmnWSpVv[3Srb36gZZN{[Xl? M3zMPFQ5KGh? Ml7XRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGXBR2M3OiClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjB|OUixJO69VQ>? MmDONVk4PDR6NUi=
IGROV1 cells NELZPHNHfW6ldHnvckBie3OjeR?= MYK0PEBp NInFTIJCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTWdTV1ZzIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTJwNUGxPFkh|ryP NWDXT2dROTl5NES4OVg>
OVCAR-3 cells NWjYWVB4TnWwY4Tpc44h[XO|YYm= MlPWOFghcA>? MXPBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iT2\DRXIuOyClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0zNjVzMUi5JO69VQ>? MVyxPVc1PDh3OB?=
OVCAR4 cells MWnGeY5kfGmxbjDhd5NigQ>? M3q3eFQ5KGh? NVzFU3FGSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG9XS0GUNDDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1zMDFOwG0> M1PtTFE6PzR2OEW4
OVCAR5 cells NVPpfZh2TnWwY4Tpc44h[XO|YYm= MlTCOFghcA>? MYHBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iT2\DRXI2KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVYvOzB7NUeg{rxu M3HEUlE6PzR2OEW4
OVCAR8 cells M4PRWmZ2dmO2aX;uJIF{e2G7 NYT6bIZQPDhiaB?= M{TLOWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDPWmNCWjhiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5zMkW4PUDPxE1? MnjLNVk4PDR6NUi=
SKOV3 cells NEn0S4JHfW6ldHnvckBie3OjeR?= MmnwOFghcA>? NFu2cpBCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2tQXjNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OS57OUWyOkDPxE1? MlLlNVk4PDR6NUi=
786-0 cells Mly3SpVv[3Srb36gZZN{[Xl? M3nocFQ5KGh? NVuy[FdwSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJFc5Pi1yIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMTFOwG0> M{myNVE6PzR2OEW4
A498 cells NG\VWmdHfW6ldHnvckBie3OjeR?= MYe0PEBp NVTONnV[SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGE1QThiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OS5{NUi5N{DPxE1? M3v6U|E6PzR2OEW4
ACHN cells M3HPWmZ2dmO2aX;uJIF{e2G7 M4TyR|Q5KGh? M1nYfWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBR2hPKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvODNzNkKg{txO MVOxPVc1PDh3OB?=
Caki1 cells NIr2RVNHfW6ldHnvckBie3OjeR?= M2TJUFQ5KGh? MkH1RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFPhb4kyKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvODNzNkKg{txO NF2y[XUyQTd2NEi1PC=>
SN12C cells NFXrN4xHfW6ldHnvckBie3OjeR?= M4DPZ|Q5KGh? NXXLXlBTSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNPOTKFIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMUm5OVMh|ryP MmG4NVk4PDR6NUi=
TK10 cells MVfGeY5kfGmxbjDhd5NigQ>? NHG2UVc1QCCq NGHhNmtCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWGsyOCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF02NjBzMUi3JO69VQ>? MkDKNVk4PDR6NUi=
UO31 cells MnK2SpVv[3Srb36gZZN{[Xl? NU\CVldsPDhiaB?= MmTPRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGXPN|Eh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4yOjV6OTFOwG0> NXLLR3Y2OTl5NES4OVg>
PC3 cells MV3GeY5kfGmxbjDhd5NigQ>? NY\6XIVNPDhiaB?= MV3BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUFOzJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUCuN|E3OjNizszN MWexPVc1PDh3OB?=
DU145 cells Mmr3SpVv[3Srb36gZZN{[Xl? MWC0PEBp MW\BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iRGWxOFUh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4zPTFzOTFOwG0> M2fYW|E6PzR2OEW4
MCF7 cells NUTGVm5mTnWwY4Tpc44h[XO|YYm= NH;teJc1QCCq NEPKT4JCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjByNkOxJO69VQ>? M{L4WFE6PzR2OEW4
NCI/ADR-RES cells NX\td21ZTnWwY4Tpc44h[XO|YYm= NG[2flM1QCCq NFvWRWJCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUmNKN0GGUj3SSXMh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NU4zPTh7MzFOwG0> NVrDT|drOTl5NES4OVg>
MDA-MB-231 cells NVn5VJNSTnWwY4Tpc44h[XO|YYm= MlHqOFghcA>? M4rmRWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUOuPVgyODdizszN MkLZNVk4PDR6NUi=
Hs 578T cells MmjMSpVv[3Srb36gZZN{[Xl? M1X2[|Q5KGh? NV\6VmtZSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGh{KDV5OGSgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;Mz65PFExPyEQvF2= NH;Ce2EyQTd2NEi1PC=>
MDA-MB-435 cells MVLGeY5kfGmxbjDhd5NigQ>? M1zwZlQ5KGh? M3PVUWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvNEO1JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUOuNVYzOjhizszN MlHsNVk4PDR6NUi=
MDA-N cells NHrUZYlHfW6ldHnvckBie3OjeR?= NY\zPVZRPDhiaB?= MXfBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW4h[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NU4zPTh7MzFOwG0> M4n2d|E6PzR2OEW4
BT549 cells NWnO[GpkTnWwY4Tpc44h[XO|YYm= MkjpOFghcA>? NH7qZ5ZCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gRnQ2PDliY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OSEQvF2= NI\NXmQyQTd2NEi1PC=>
T47D cells Ml\hSpVv[3Srb36gZZN{[Xl? M1PafFQ5KGh? MmXXRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGS0O2Qh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NU4zPTh7MzFOwG0> MV[xPVc1PDh3OB?=
HepG2 cells NGWyXlREgXSxdH;4bYNqfHliYYPzZZk> NIG5VVg4OiCq MXPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBGSzVyPUG4Mlg1KM7:TR?= MVmxPVkyPzV{OB?=
A549 cells MUTDfZRwfG:6aXPpeJkh[XO|YYm= NITETm44OiCq MV\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGVEPTB;OT63OEDPxE1? MnLlNVk6OTd3Mki=
LAC cells M1u4UGN6fG:2b4jpZ4l1gSCjc4PhfS=> NYfm[oFTPzJiaB?= NYTxUHpwS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVEGFIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEWFNUC9N|IvODlizszN NWjHWYFEOTl7MUe1Nlg>
HeLa cells MUXDfZRwfG:6aXPpeJkh[XO|YYm= Ml7aO|IhcA>? NFfDPXNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEWFNUC9NVAvOjZizszN M3\SXVE6QTF5NUK4
MDA-MB-231 cells NE\iXJlEgXSxdH;4bYNqfHliYYPzZZk> M3HRW2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj2yN|Eh[2WubIOgc5ZmemW6cILld5NqdmdidYLvb4lv[XOnIIDsZZNucW6xZ3XuJIFkfGm4YYTvdkwhUUN3ME2wMlIyKM7:TR?= NXuyOHhyOjB|NkOxN|A>
human ACHN cells NYDaO3hLTnWwY4Tpc44h[XO|YYm= MmPoRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFHDTG4h[2WubIOgZpkhW1KEIHHzd4F6NCCJSUWwQVIvOSEQvF2= MWKyNFc{OjhzMB?=
PC3 cells M4O0TGZ2dmO2aX;uJIF{e2G7 NXrEfWQ5SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHBEOyClZXzsd{BjgSCVUlKgZZN{[XluIFfJOVA:PC57NzFOwG0> M1\xfFIxPzN{OEGw
MDA-MB-231 cells MX\GeY5kfGmxbjDhd5NigQ>? MYfBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTJ|MTDj[YxteyCkeTDTVmIh[XO|YYmsJGdKPTB;MD6xOkDPxE1? NHvjfWUzODd|MkixNC=>
FM3A cells M33TfWZ2dmO2aX;uJIF{e2G7 MknJNkBl[Xm| M4nx[WN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDGUVNCKGOnbHzzJIFnfGW{IEKg[IF6eyCkeTDjc5VtfGW{IHPveY51cW6pIHHuZYx6e2m|LDDJR|UxRTBwMEC5OEDPxE1? MoX1NlE{OzByMUS=
HeLa cells NFXiTmRHfW6ldHnvckBie3OjeR?= MWnDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDpckBxemW|ZX7j[UBw\iB{MDD1UUB1cHmvaXTpcoUtKEmFNUC9PE42KM7:TR?= MkDrNlE{OzByMUS=
LLC cells NVfNV5B6S3m2b4TvfIlkcXS7IHHzd4F6 NFjsO40zPCCq NWTyfoFUS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVEyFIHPlcIx{KGGodHXyJFI1KGi{czDifUBz\XOjeoXybY4h[XO|YYmsJGlEPTB;MUSuNkDPxE1? MkS1NlE2OzZ2NEi=
LLC cells NIK1[HZEgXSxdH;4bYNqfHliYYPzZZk> MlHpO|IhcA>? NUniW5AyS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVEyFIHPlcIx{KGGodHXyJFczKGi{czDifUBz\XOjeoXybY4h[XO|YYmsJGlEPTB;MjFOwG0> M3\UZlIyPTN4NES4
RAW264.7 cells M1P4e2N6fG:2b4jpZ4l1gSCjc4PhfS=> NVSwbGNmPzJiaB?= MlvDR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgVmFYOjZ2LkegZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KHKnc3H6eZJqdiCjc4PhfUwhUUN3ME2zNEDPxE1? MoXHNlE2OzZ2NEi=
A549 cells M1HWXmN6fG:2b4jpZ4l1gSCjc4PhfS=> M2OwVVczKGh? MWLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IEeyJIhzeyCkeTDXV3QuQCCjc4PhfUwhUUN3ME2wMlA1PyEQvF2= M{P1O|IzOjR6OEW2
A2780 cells NHLzbppEgXSxdH;4bYNqfHliYYPzZZk> NFz5Xnc2KGSjeYO= NWrRWoE5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTJ5OECgZ4VtdHNiYX\0[ZIhPSCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NF0xNjB{NjFOwG0> NGPOTYgzOjd|OE[zOi=>
LMTK cells MVjDfZRwfG:6aXPpeJkh[XO|YYm= MkThOUBl[Xm| NELlZodEgXSxdH;4bYNqfHliYXfhbY5{fCC2aIntbYRqdmVia3nuZZNmNWSnZnnjbYVvfCCvb4Xz[UBNVVSNIHPlcIx{KGGodHXyJFUh\GG7czDifUBOXFRiYYPzZZktKEmFNUC9OE42KM7:TR?= Mkn4NlI4Ozh4M{[=
A549 cells MY\DfZRwfG:6aXPpeJkh[XO|YYm= NInwc2E4OiCq NGryVZREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFczKGi{czDifUBucWO{b4DsZZRmKHKnYXTldkBu\XSqb3SsJGlEPTB;MD6wNVI1KM7:TR?= MVWyNlg1PzBzOR?=
CEM cells NHe3SGpHfW6ldHnvckBie3OjeR?= NFPM[444OiCq M3f4TmN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOg[ZhxemW|c3nu[{BpfW2jbjDFUnQyKHS{YX7zdI9zfGW{IHHmeIVzKDd{IHjyd{BjgSClZXzsJINwfW62aX7nJIlvKHC{ZYPlcoNmKG:oIF7CUXBTNCCLQ{WwQVAvQCEQvF2= MYSyNVg6Ojh{OR?=
Hela cells NVLBOoRzTnWwY4Tpc44h[XO|YYm= NWi4PGlPPzJiaB?= MWPDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDh[pRmeiB5MjDodpMh[nliY3XscEBkd3WwdHnu[{whUUN3ME2wMlA2KM7:TR?= M2XqSlIyQDl{OEK5
CEM/0 cells NHjlWZdHfW6ldHnvckBie3OjeR?= MYG3NkBp NYK4R3FJS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGNGVS9yIHPlcIx{KGGodHXyJFczKGi{czDifUBk\WyuIHPveY51cW6pLDDJR|UxRTBwMEKyJO69VQ>? MXyyNVg6Ojh{OR?=
L1210/0 cells NYnYRndmTnWwY4Tpc44h[XO|YYm= MnL0OFghcA>? MmSzR5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JI1wfXOnIFyxNlExNzBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JINmdGxiY3;1cpRqdmduIFnDOVA:OC5yMEC5JO69VQ>? NH\UVFczOTh7MkiyPS=>
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HeLa cells M2TmXWN6fG:2b4jpZ4l1gSCjc4PhfS=> NF31WZA4OiCq NX3zeJBXS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjZoTldkA4OiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwQVYvPSEQvF2= MYeyN|g3PzZyMx?=
HL60 cells NXTPU4I5WHKxbHnm[ZJifGmxbjDhd5NigQ>? NX[0[WdqPzJiaB?= MlnERY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKTE[wJINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTB;MD6yOEDPxE1? MX2yOVY1PDZ5NB?=
SW707 cells MVHQdo9tcW[ncnH0bY9vKGG|c3H5 MmTYO|IhcA>? NX\PclhFSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|cxPyClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkA4OiCqcoOgZpkhW1KEIH3leIhw\CxiSVO1NF0zOy56NjFOwG0> NYLTVY45OjV4NES2O|Q>
LoVo cells MVvQdo9tcW[ncnH0bY9vKGG|c3H5 NFXZUIQ4OiCq MUfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEyxVn:gZ4VtdHNiYYPz[ZN{\WRiYYOg[5Jwf3SqIHnubIljcXSrb36gZYZ1\XJiN{KgbJJ{KGK7IGPSRkBu\XSqb3SsJGlEPTB;MUmuNFch|ryP M4X6SFI2PjR2Nke0
BALB/3T3 cell NIXIWlNRem:uaX\ldoF1cW:wIHHzd4F6 MWK3NkBp M1fJZmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViQlHMRk8{XDNiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KFOUQjDt[ZRpd2RuIFnDOVA:OjNwOTFOwG0> MnXBNlU3PDR4N{S=
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CCRFCEM cells MXnGeY5kfGmxbjDhd5NigQ>? NUfxcVB[S3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGNEWk[FRV2gZ4VtdHNiYomgUXRVKGG|c3H5MEBKSzVyPUCuNlkh|ryP MVOxO|gxPDJ|MR?=
RXF393 cells MlvMSpVv[3Srb36gZZN{[Xl? NUfKSoRNPDhiaB?= MYjBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUmjGN|k{KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVMvQThzMEeg{txO NFrm[IwyQTd2NEi1PC=>
HL-60(TB) cells MV7GeY5kfGmxbjDhd5NigQ>? MXi0PEBp NInDT21CdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGwuPjBqVFKpJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUCuNVk6PTNizszN MWixPVc1PDh3OB?=
L1210 cells MVvGeY5kfGmxbjDhd5NigQ>? NWDpWXN6OTVibXnudy=> NGLUfoJKdmirYnn0bY9vKG:oIITofY1q\HmuYYTlJJN6dnSqYYPlJIlvKG2xdYPlJGwyOjFyIHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4YhfHKrdHn1cUBz\WynYYPlJIZzd21iW{WtN2he\GWxeIn1dollcW6nIHHmeIVzKHC{ZXnuZ5Vj[XSrb36g[o9zKDF3IH3pcpMh[nlibHnxeYllKHOlaX70bYxt[XSrb36gZ492dnSrbnesJGlEPTB;MD6wNFA3KM7:TR?= M3WycFIyOzNyMEG0
Colo-357 cells NIrQO3hHfW6ldHnvckBie3OjeR?= MXOxNFAh|ryP NIH4[JYyPSCvaX7z Mn;BRYN1cX[rdImgZZQhVVKSNTDpckBpfW2jbjDDc4xwNTN3NzDj[YxteyCjc4Pld5Nm\CCjczC1MWZlXU2SIHHjZ5VufWyjdHnvckBifCBzMECgeW0h[W[2ZYKgNVUhdWmwcx?= M3jHV|IxQTNyMUKz
KB cells MofER5l1d3SxeHnjbZR6KGG|c3H5 NV7hWJN5PzJiaB?= MWHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLRkBk\WyuczDh[pRmeiB5MjDodpMh[nliU2LCJIF{e2G7LDDJR|UxRThwNkmg{txO NHrRe3QzOzh4N{[wNy=>

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 49 mg/mL (199.03 mM)
Water 49 mg/mL (199.03 mM)
Ethanol ''10 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 246.19
Formula

C9H11FN2O5

CAS No. 50-91-9
Storage powder
in solvent
Synonyms Deoxyfluorouridine, FUDR, NSC 27640
Smiles C1C(C(OC1N2C=C(C(=O)NC2=O)F)CO)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

DNA/RNA Synthesis Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID