Floxuridine (NSC 27640)

For research use only.

Catalog No.S1299 Synonyms: Deoxyfluorouridine, FUDR

8 publications

Floxuridine (NSC 27640) Chemical Structure

CAS No. 50-91-9

Floxuridine (NSC 27640, Deoxyfluorouridine, FUDR) is a prodrug that is rapidly catabolized to 5-fluorouracil in vivo. Floxuridine is used to treat various cancers, particularly metastases to the liver. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage and apoptosis. Floxuridine has antiviral effects against HSV and CMV.

Selleck's Floxuridine (NSC 27640) has been cited by 8 publications

Purity & Quality Control

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description Floxuridine (NSC 27640, Deoxyfluorouridine, FUDR) is a prodrug that is rapidly catabolized to 5-fluorouracil in vivo. Floxuridine is used to treat various cancers, particularly metastases to the liver. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage and apoptosis. Floxuridine has antiviral effects against HSV and CMV.
In vitro

Floxuridine exhibits higher affinity for PEPT1 than the corresponding 5'-O-mono amino acid ester prodrugs. [1] Floxuridine combined with Leucovorin results in synergistic inhibitory effects on growth of human T-lymphoblast leukemia cells. [2] Floxuridine significantly inhibits the uptake of both [(3)H]-inosine and [(3)H]-adenosine (60-70% of control), while its amino acid ester prodrugs including Val, Phe, Pro, Asp, and Lys esters exhibits markedly decreased inhibition potency (10-30% of control). [3] Floxuridine inhibits cell proliferation by more than 50% relative to the untreated control cells at 36 days, the cell numbers still increases fourfold compared with the initial cell density. Floxuridine results in prolonged effects on the proliferation of human Tenon's capsule fibroblasts in vitro. [4] Floxuridine (FUDR) is an ideal drug for hepatic arterial infusion (HAI) due to its short half life, steep dose response curve, high total body clearance, and high hepatic extraction. [5]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
CCRF-CEM cell Mn;rS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWfU[ZN1\WRiaX6geol1em9iZn;yJJRp\SCrbnjpZol1cW:wIH;mJINmdGxiZ4Lve5RpKG:oIHj1cYFvKFRibIntdIhw[myjc4TvbYQhS0OURj3DSW0h[2WubDDsbY5mKCiDVFPDJGNEVCBzMUmpMEBKSzVyPUCuOUDPxE1? MVSxNVkxQTdzNh?=
CCRF-CEM M2njUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkfGTY4hfmm2cn:gZ49v[2WwdILheIlwdiC{ZYH1bZJm\CCob4KgOVAmKGmwaHnibZRqd25ib3[g[5Jwf3SqIH;mJIh2dWGwIHzleYtmdWmjIHPlcIwhdGmwZTDDR3JHNUOHTTD3bZRpKGiSQWCgLFAvOiC3bnn0M41NMSxiR1m1NF0xNjByME[g{txO NFrwdVEyOTV7N{SwOC=>
LNCaP cells NEjBXlVEgXSxdH;4bYNqfHliYYPzZZk> NHnx[FJEgXSxdH;4bYMh[2:wY3XueJJifGmxbjDpckBxem:|dHH0[UB{eGWlaX\pZ{BidnSrZ3XuJEhRW0FrIIDyc4R2[2mwZzDoeY1idiCOTlPhVEBk\WyuczygTWM2OD1yLkC2PVIh|ryP NFzRUFcyOjF4MUG1Oy=>
TSU cells NWDKdIJTS3m2b4TvfIlkcXS7IHHzd4F6 MnjJR5l1d3SxeHnjJINwdmOnboTyZZRqd25iaX6gco9vKHC{b4P0ZZRmKHOyZXPp[olkKGGwdHnn[Y4hMFCVQTmgdJJw\HWlaX7nJIh2dWGwIGTTWUBk\WyuczygTWM2OD1yLkC1PEDPxE1? M4O2dVEzOTZzMUW3
KBALB cell MXPDfZRwfG:6aXPpeJkh[XO|YYm= MorDTY4hfmm2cn:gZ4VtdCCleYTveI95cWOrdImgZYdicW6|dDDLRmFNSiClZXzsJIxqdmViKITyZY5{\m:{bXXkJIZq[nKxYnzhd5Qhe2G{Y3;tZUBk\WyuIHzpcoUqNCCFQ{WwQVYvODCHLUC1JO69VQ>? M2LQO|EzPjJyMEe2
KBALB-STK cell NGfaRYlEgXSxdH;4bYNqfHliYYPzZZk> NF2yNWRKdiC4aYTyc{Bk\WyuIHP5eI91d3irY3n0fUBi\2GrboP0JGtDSUyELWPUT{Bk\WyuIHzpcoV{KGW6cILld5Nm\CCrbjDIV3YuOSCWSzygTWM2OD16LkiwSU0xPSEQvF2= NWG2ZpJEOTJ4MkCwO|Y>
L1210 mouse leukemia cells M{LCN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXK1bpVIOjRiaB?= NXL6cYRtT3Kxd4ToJIlvcGmkaYTpc44hcW5iTEGyNVAhdW:3c3WgcIV2c2WvaXGgZ4VtdHNiYX\0[ZIhOjRiaDD0doVifG2nboSsJGlEPTB;MD6wNFQyKM7:TR?= MkPpNVE4OjhzOUO=
L1210 mouse leukemia cells M2PQN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFPDZYs1QCCq MV7Hdo94fGhiaX7obYJqfGmxbjDpckBNOTJzMDDtc5V{\SCuZYXr[Y1q[SClZXzsd{Bi\nSncjC0PEBpeiC2cnXheI1mdnRuIFnDOVA:OC5yMEC2OEDPxE1? NIO3[GcyOTd{OEG5Ny=>
L5178Y cell M12yXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlLNR49ueGG{YYTpeoUhcW6qaXLpeIlwdiCxZjDMOVE4QFliY3XscEBoem:5dHigbY4hfmm2cn:gLINwdmOnboTyZZRqd25icnXxeYlz\WRiZn;yJFUxLSCrbnjpZol1cW:wKTygTWM2OD1yLkCwNFc3KM7:TR?= NXPtVYFXPjd5OUCwOy=>
L5178Y cells Mn2wSpVv[3Srb36gZZN{[Xl? MnXVTY5pcWKrdH;yfUBkd26lZX70doF1cW:wIH;mJINwdXCxdX7kJJdieyClYXzjeYxifGWmIH;uJGw2OTd6WTDj[YxteyCkeTDbNVREZUyndTDpcoNwenCxcnH0bY9vNCCLQ{WwQVIh|ryP M3Tv[lgzPDZ{Mkm=
L1210 mouse leukemia cells NFHTeVdHfW6ldHnvckBie3OjeR?= NInJU4wzKGh? MYfUbJlucWS7bHH0[UB{gW62aHHz[UBqdmirYnn0bY9vKGmwIFyxNlExKG2xdYPlJIxmfWunbXnhJINmdGy|IHHmeIVzKDJiaIKgeJJm[XSvZX70MEBKSzVyPUCuNFA4QSEQvF2= NH64U48yOTd{OEG5Ny=>
LM cells NWrZPGdOTnWwY4Tpc44h[XO|YYm= NY[2PI43OiCq M1zpXHRpgW2rZInsZZRmKHO7boToZZNmKGmwaHnibZRqd25iaX6geIh6dWmmaX7lJItqdmG|ZTDk[YZq[2mnboSgUG0h[2WubIOgZYZ1\XJiMjDodkB1emWjdH3lcpQtKEmFNUC9OU41KM7:TR?= MXKxNVczQDF7Mx?=
HT1080 cells M4W5WGZ2dmO2aX;uJIF{e2G7 MXHDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSGSxNFgxKGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NF0xNjF6IN88US=> NIDUbHMyPzhyNEKzNS=>
L1210 cells NVHqdpA3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NE\P[Vk4OiCq NVLEWoR3S3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KG2xdYPlJGwyOjFyIHPlcIx{KEGWQ1OgR2NNOjF7IHHzd4V{e2WmIHHzJIdzd3e2aDDy[YR2[3Srb36gZYZ1\XJiN{KgbJJ{NCCLQ{WwQVAvODF{IN88US=> MXKxO|k6PzNzOR?=
HL60 cells Mle2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlTVO|IhcA>? MYLDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFy2NEBk\WyuczDBWGNEKEOFTDCyOFAh[XO|ZYPz[YQh[XNiZ4Lve5RpKHKnZIXjeIlwdiCjZoTldkA4OiCqcoOsJGlEPTB;MD6wNVIh|ryP NFLqWIwyPzl7N{OxPS=>
CCRF-CEM cells NXzwVY9TT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIn6XIk4OiCq M3LQb2N6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDR3JHNUOHTTDj[YxteyCDVFPDJGNEVCBzMUmgZZN{\XO|ZXSgZZMh\3Kxd4ToJJJm\HWldHnvckBi\nSncjC3NkBpenNuIFnDOVA:OC5yMUeg{txO MmHkNVc6QTd|MUm=
L1210 cells MkT4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYe3NkBp MkjkR5l1d3O2YYTpZ{Bi[3Srdnn0fUBqdiCvb4Xz[UBNOTJzMDDj[YxteyCjc4Pld5Nm\CCjczDpcohq[mm2aX;uJI9nKGOnbHyg[5Jwf3SqIHHmeIVzKDd{IHjyd{whUUN3ME2wMlAyOiEQvF2= M3PpUlE5ODd6N{W3
HL60 cells NIXCdZBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWTkc|FWPzJiaB?= M4fnZWN6fG:|dHH0bYMh[WO2aY\peJkhcW5iaIXtZY4hUEx4MDDj[YxteyCjc4Pld5Nm\CCjczDpcohq[mm2aX;uJI9nKGOnbHyg[5Jwf3SqIHHmeIVzKDd{IHjyd{whUUN3ME2wMlAyOiEQvF2= MYixPFA4QDd3Nx?=
CCRF-CEM cells NXfaU4FiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHzMfFM4OiCq NXfzZ|JES3m2b4P0ZZRq[yCjY4Tpeol1gSCrbjDoeY1idiCFQ2LGMWNGVSClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJINmdGxiZ4Lve5RpKGGodHXyJFczKGi{czygTWM2OD1yLkCxO{DPxE1? NIXIRVEyQDB5OEe1Oy=>
CCRF-CEM cells NHjORmVHfW6ldHnvckBie3OjeR?= NF;HUXE1QCCq NH7ORWtCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gR2NTTi2FRV2gZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MD6wNFY{OSEQvF2= M17tVFE6PzR2OEW4
K562 cells NIHEN2JHfW6ldHnvckBie3OjeR?= MmT5OFghcA>? Mn;tRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFu1OlIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE44QTR|MzFOwG0> M1HFTVE6PzR2OEW4
MOLT4 cells MYTGeY5kfGmxbjDhd5NigQ>? MnS4OFghcA>? NFnxeWxCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUW9NXDRiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5yM{m4NUDPxE1? M4DPZVE6PzR2OEW4
RPMI8266 cells NVywfnQzTnWwY4Tpc44h[XO|YYm= M2OyV|Q5KGh? M1e1RWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDSVG1KQDJ4NjDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLke5OFM{KM7:TR?= NVrtd|FxOTl5NES4OVg>
human SR cells MV3GeY5kfGmxbjDhd5NigQ>? NFOyU2o1QCCq NXz1RlZxSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNTKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvODF{NUmg{txO MVyxPVc1PDh3OB?=
A549 cells NYnSUZM2TnWwY4Tpc44h[XO|YYm= NIK4eGs1QCCq NVnlWIEySW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5yMUK1PUDPxE1? M{XNVlE6PzR2OEW4
EKVX cells Mn\xSpVv[3Srb36gZZN{[Xl? NGnL[JI1QCCq MmnrRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFXLWngh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NVAh|ryP M1yxRlE6PzR2OEW4
HOP62 cells NULWUlJuTnWwY4Tpc44h[XO|YYm= NGT4clk1QCCq M3XJbWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIU3A3OiClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjB{NUGyJO69VQ>? M{\F[FE6PzR2OEW4
HOP92 cells MkPmSpVv[3Srb36gZZN{[Xl? NWjUSW5rPDhiaB?= MkjtRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjPVFkzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvPzl2M{Og{txO MnvuNVk4PDR6NUi=
NCI-H226 cells NWC3bFNwTnWwY4Tpc44h[XO|YYm= MYC0PEBp MWLBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWgzOjZiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[Xl? M3rJRlE6PzR2OEW4
NCI-H23 MWjGeY5kfGmxbjDhd5NigQ>? M2L0XFQ5KGh? MWPBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWgzOyClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0yOCEQvF2= MXSxPVc1PDh3OB?=
NCI-H322 NFPRfHVHfW6ldHnvckBie3OjeR?= MkPJOFghcA>? NVzpfXRtSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KM{KyUUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2wMlUxOTF7IN88US=> M3rrdVE6PzR2OEW4
NCI-H460 MUjGeY5kfGmxbjDhd5NigQ>? NYq3NZEzPDhiaB?= MYnBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWg1PjBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC53MEGxPUDPxE1? M3zVS|E6PzR2OEW4
NCI-H522 M3\Ud2Z2dmO2aX;uJIF{e2G7 NXLDTVltPDhiaB?= M4i1RWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kuUDV{MjDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLkCwNkDPxE1? Mlv6NVk4PDR6NUi=
COLO205 cells NULWRZQ6TnWwY4Tpc44h[XO|YYm= NXn2cGVSPDhiaB?= NG\0[GRCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gR29NVzJyNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1{LkWxNVg6KM7:TR?= MVqxPVc1PDh3OB?=
HCC2998 cells MoLpSpVv[3Srb36gZZN{[Xl? NYPhR3JyPDhiaB?= MV7BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPDNlk6QCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0yNjV6NEi5JO69VQ>? NWrmRYZpOTl5NES4OVg>
HCT116 cells NGTUNJVHfW6ldHnvckBie3OjeR?= MWG0PEBp MX\BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPUNVE3KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvODBzIN88US=> M3z0S|E6PzR2OEW4
HCT15 cells NGDUXHdHfW6ldHnvckBie3OjeR?= MnT4OFghcA>? NHPGPGNCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGNVOTViY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5zMkW4PUDPxE1? MnzYNVk4PDR6NUi=
HT-29 cells M4DUSmZ2dmO2aX;uJIF{e2G7 NUT4NmlYPDhiaB?= M1jy[mFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0yNjl7NUK2JO69VQ>? MYmxPVc1PDh3OB?=
KM12 cells NH\kOGpHfW6ldHnvckBie3OjeR?= Ml7uOFghcA>? NWDQNmZUSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGtOOTJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:Oi53MUG4PUDPxE1? MYixPVc1PDh3OB?=
SW620 cells MnfOSpVv[3Srb36gZZN{[Xl? M3e1elQ5KGh? MnzHRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPXOlIxKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVYvOzB7NUeg{txO NV\HbIVIOTl5NES4OVg>
SF268 cells M3LuSWZ2dmO2aX;uJIF{e2G7 MVq0PEBp NFi4UoZCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2YzPjhiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OTBizszN NFnkfogyQTd2NEi1PC=>
SF295 cells NYXqUFdDTnWwY4Tpc44h[XO|YYm= NHzNd2o1QCCq M3jaWWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTSlI6PSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjBzMkW5JO69VQ>? MlLCNVk4PDR6NUi=
SF539 cells MoDrSpVv[3Srb36gZZN{[Xl? NWfxWWVjPDhiaB?= MXrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU1[1N|kh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4xOzl6MTFOwG0> MoXuNVk4PDR6NUi=
SNB19 cells NHnNVVhHfW6ldHnvckBie3OjeR?= NEPufGc1QCCq NIK3eGdCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV25DOTliY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OS57OUWyOkDPxE1? MWOxPVc1PDh3OB?=
SNB75 cells NV[0VmN4TnWwY4Tpc44h[XO|YYm= NIPIUoE1QCCq NX7VT|VxSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNPSjd3IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMUm5OVMh|ryP Mm\INVk4PDR6NUi=
U251 cells NV3jSIoxTnWwY4Tpc44h[XO|YYm= NXrhUVN3PDhiaB?= NFHhTHhCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWVI2OSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjF{NUi5JO69VQ>? M3rKTlE6PzR2OEW4
LOXIMVI cells Mli4SpVv[3Srb36gZZN{[Xl? NXy4TpJIPDhiaB?= M3zZSGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDMU3hKVV[LIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEK1NVIh|ryP NYHMXZpTOTl5NES4OVg>
MALME-3M cells NIPzfmNHfW6ldHnvckBie3OjeR?= MnzQOFghcA>? M2nDOGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNRWxOTS1|TTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD15Lkm0N|I5KM7:TR?= Mon2NVk4PDR6NUi=
M14 cells NGnSU4xHfW6ldHnvckBie3OjeR?= NHry[Fk1QCCq MoLiRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF2xOEBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2wMlE2QDR7IN88US=> NE\p[4EyQTd2NEi1PC=>
SK-MEL-2 cells M3P4fGZ2dmO2aX;uJIF{e2G7 NWH0bGFDPDhiaB?= NEDvWJhCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2suVUWOLUKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MUCg{txO M{G4RVE6PzR2OEW4
SK-MEL-28 cells MYnGeY5kfGmxbjDhd5NigQ>? M12y[lQ5KGh? NUS2d2dXSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNMNU2HTD2yPEBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2xMlk6PTJ4IN88US=> MlzINVk4PDR6NUi=
SK-MEL-5 cells MUjGeY5kfGmxbjDhd5NigQ>? NH7Temk1QCCq MluxRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPLMW1GVC13IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMUm5OVMh|ryP NXHoS5E4OTl5NES4OVg>
UACC257 cells NVTaWZh6TnWwY4Tpc44h[XO|YYm= M1jhelQ5KGh? NFqxdJdCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWWFESzJ3NzDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1|LkG2NlI5KM7:TR?= Mli2NVk4PDR6NUi=
UACC62 cells MVzGeY5kfGmxbjDhd5NigQ>? M3;nT|Q5KGh? NGrocFlCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWWFESzZ{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEO5PFEh|ryP MVyxPVc1PDh3OB?=
IGROV1 cells NXziT3B1TnWwY4Tpc44h[XO|YYm= M3fEdVQ5KGh? M4jNb2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDJS3JQXjFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:Oi53MUG4PUDPxE1? Mk\LNVk4PDR6NUi=
OVCAR-3 cells NF7oc3JHfW6ldHnvckBie3OjeR?= Mm\6OFghcA>? NHXDR|VCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gU3ZESVJvMzDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1{LkWxNVg6KM7:TR?= NGS3OXEyQTd2NEi1PC=>
OVCAR4 cells MUfGeY5kfGmxbjDhd5NigQ>? M1zkdlQ5KGh? MkK1RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF;WR2FTPCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0yOCEQvF2= M2LSflE6PzR2OEW4
OVCAR5 cells NGi3cVRHfW6ldHnvckBie3OjeR?= MmHwOFghcA>? Mm\ORY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF;WR2FTPSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF03NjNyOUW3JO6ddQ>? NFu1dYwyQTd2NEi1PC=>
OVCAR8 cells Mof1SpVv[3Srb36gZZN{[Xl? MX60PEBp MkHyRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF;WR2FTQCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjF{NUi5JO69VQ>? M33KT|E6PzR2OEW4
SKOV3 cells M4fTTmZ2dmO2aX;uJIF{e2G7 M2f1XFQ5KGh? NWLIdXJkSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNMV1Z|IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFwOUm1NlYh|ryP NV;KTWRCOTl5NES4OVg>
786-0 cells M2HoN2Z2dmO2aX;uJIF{e2G7 MnXZOFghcA>? NXPOOJIySW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJFc5Pi1yIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMTFOwG0> M2LUe|E6PzR2OEW4
A498 cells NWfGNG5UTnWwY4Tpc44h[XO|YYm= MnrvOFghcA>? M{C3RWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOFk5KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVEvOjV6OUOg{txO M3jL[FE6PzR2OEW4
ACHN cells MmLxSpVv[3Srb36gZZN{[Xl? M{O2NFQ5KGh? NUfYPGw5SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGFEUE5iY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5yM{G2NkDPxE1? NF\i[5UyQTd2NEi1PC=>
Caki1 cells M3n4PWZ2dmO2aX;uJIF{e2G7 NFHDeWk1QCCq NYDqPWY3SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGNic2lzIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEOxOlIh|ryP MX[xPVc1PDh3OB?=
SN12C cells MXfGeY5kfGmxbjDhd5NigQ>? NHnTelU1QCCq NXu1N3d4SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNPOTKFIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMUm5OVMh|ryP MWixPVc1PDh3OB?=
TK10 cells M3\KdGZ2dmO2aX;uJIF{e2G7 MnLrOFghcA>? NXjBVJFvSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHRMOTBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:PS5yMUG4O{DPxE1? NWfjcoFvOTl5NES4OVg>
UO31 cells NYq0T5N6TnWwY4Tpc44h[XO|YYm= MUK0PEBp M1y0T2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDVU|MyKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvOTJ3OEmg{txO MVGxPVc1PDh3OB?=
PC3 cells MXfGeY5kfGmxbjDhd5NigQ>? MnTqOFghcA>? NHO1eGhCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvOzF4MkOg{txO MkjCNVk4PDR6NUi=
DU145 cells M4jEOWZ2dmO2aX;uJIF{e2G7 MmfoOFghcA>? MX\BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iRGWxOFUh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4zPTFzOTFOwG0> MUKxPVc1PDh3OB?=
MCF7 cells M2HrbWZ2dmO2aX;uJIF{e2G7 MVW0PEBp MWrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2wMlAxPjNzIN88US=> M2H5XFE6PzR2OEW4
NCI/ADR-RES cells M1\JZmZ2dmO2aX;uJIF{e2G7 M{nFd|Q5KGh? MlnPRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7DTU9CTFJvUlXTJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUGuNlU5QTNizszN Mmi0NVk4PDR6NUi=
MDA-MB-231 cells NU[xWWd1TnWwY4Tpc44h[XO|YYm= MkO4OFghcA>? NEXr[I5CdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2zMlk5OTB5IN88US=> MXqxPVc1PDh3OB?=
Hs 578T cells M{T0O2Z2dmO2aX;uJIF{e2G7 NVXVR2JPPDhiaB?= NX;NVmxwSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGh{KDV5OGSgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;Mz65PFExPyEQvF2= NXvOSZJVOTl5NES4OVg>
MDA-MB-435 cells NIHJWpNHfW6ldHnvckBie3OjeR?= MlXmOFghcA>? NUTjOpVvSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj20N|Uh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9N{4yPjJ{ODFOwG0> MnXuNVk4PDR6NUi=
MDA-N cells MoD3SpVv[3Srb36gZZN{[Xl? M{LZZVQ5KGh? Moe2RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1PKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVEvOjV6OUOg{txO NETMd2gyQTd2NEi1PC=>
BT549 cells Mlq2SpVv[3Srb36gZZN{[Xl? NIPVVnU1QCCq NVPCS2xxSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGJVPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFizszN Ml31NVk4PDR6NUi=
T47D cells NXW2O2llTnWwY4Tpc44h[XO|YYm= MWO0PEBp Mn63RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGS0O2Qh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NU4zPTh7MzFOwG0> MXuxPVc1PDh3OB?=
HepG2 cells NGHuVnREgXSxdH;4bYNqfHliYYPzZZk> MW[3NkBp M{LNeWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEWFNUC9NVgvQDRizszN MnS2NVk6OTd3Mki=
A549 cells MnPwR5l1d3SxeHnjbZR6KGG|c3H5 MkPjO|IhcA>? NW\FeoVwS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCHQ{WwQVkvPzRizszN M{PwV|E6QTF5NUK4
LAC cells Mk\hR5l1d3SxeHnjbZR6KGG|c3H5 MmTwO|IhcA>? M4nvUWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGxCSyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBGSzVyPUOyMlA6KM7:TR?= M2O3UFE6QTF5NUK4
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MDA-MB-231 cells M2K1NWN6fG:2b4jpZ4l1gSCjc4PhfS=> NHG3eHVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOTEFvTVKtNlMyKGOnbHzzJI93\XKneIDy[ZN{cW6pIIXyc4tqdmG|ZTDwcIF{dWmwb3flckBi[3SrdnH0c5ItKEmFNUC9NE4zOSEQvF2= M1SxNlIxOzZ|MUOw
human ACHN cells M2HvS2Z2dmO2aX;uJIF{e2G7 MU\BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQVPIUkBk\WyuczDifUBUWkJiYYPzZZktKEeLNUC9Nk4yKM7:TR?= NITXdnEzODd|MkixNC=>
PC3 cells M3noNWZ2dmO2aX;uJIF{e2G7 NHPFbJFCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIJ6KFOUQjDhd5NigSxiR1m1NF01Njl5IN88US=> MlHoNlA4OzJ6MUC=
MDA-MB-231 cells NUWyeWRkTnWwY4Tpc44h[XO|YYm= NETH[|lCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDifUBUWkJiYYPzZZktKEeLNUC9NE4yPiEQvF2= NVXkN2xpOjB5M{K4NVA>
FM3A cells MVPGeY5kfGmxbjDhd5NigQ>? MYOyJIRigXN? M2LqSmN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDGUVNCKGOnbHzzJIFnfGW{IEKg[IF6eyCkeTDjc5VtfGW{IHPveY51cW6pIHHuZYx6e2m|LDDJR|UxRTBwMEC5OEDPxE1? NXu0VWNtOjF|M{CwNVQ>
HeLa cells M{P0XGZ2dmO2aX;uJIF{e2G7 NXLNdIFpS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMhcW5icILld4Vv[2Vib3[gNlAhfU1idHj5cYllcW6nLDDJR|UxRThwNTFOwG0> Moe5NlE{OzByMUS=
LLC cells MX\DfZRwfG:6aXPpeJkh[XO|YYm= M{iyT|I1KGh? NXO5XlhbS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVEyFIHPlcIx{KGGodHXyJFI1KGi{czDifUBz\XOjeoXybY4h[XO|YYmsJGlEPTB;MUSuNkDPxE1? M2jZOVIyPTN4NES4
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RAW264.7 cells NWPIWHRoS3m2b4TvfIlkcXS7IHHzd4F6 MYW3NkBp M4n0V2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KG2xdYPlJHJCXzJ4ND63JINmdGy|IHHmeIVzKDd{IHjyd{BjgSC{ZYPhfpVzcW5iYYPzZZktKEmFNUC9N|Ah|ryP NF;tbZczOTV|NkS0PC=>
A549 cells MmHiR5l1d3SxeHnjbZR6KGG|c3H5 NVrEOoVlPzJiaB?= M3\oXGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgO|IhcHK|IHL5JHdUXC16IHHzd4F6NCCLQ{WwQVAvODR5IN88US=> MYSyNlI1QDh3Nh?=
A2780 cells MmDKR5l1d3SxeHnjbZR6KGG|c3H5 M1\pXVUh\GG7cx?= NU\BUlc2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTJ5OECgZ4VtdHNiYX\0[ZIhPSCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NF0xNjB{NjFOwG0> NX;CSZQ6OjJ5M{i2N|Y>
LMTK cells MW\DfZRwfG:6aXPpeJkh[XO|YYm= NWPoeGdGPSCmYYnz Moj1R5l1d3SxeHnjbZR6KGGpYXnud5QhfGi7bXnkbY5mKGurbnHz[U1l\W[rY3nlcpQhdW:3c3WgUG1VUyClZXzsd{Bi\nSncjC1JIRigXNiYomgUXRVKGG|c3H5MEBKSzVyPUSuOUDPxE1? MWWyNlc{QDZ|Nh?=
A549 cells NWTvPWVXS3m2b4TvfIlkcXS7IHHzd4F6 M2myN|czKGh? M1PJe2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgO|IhcHK|IHL5JI1q[3KxcHzheIUhemWjZHXyJI1mfGixZDygTWM2OD1yLkCxNlQh|ryP M1fSN|IzQDR5MEG5
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Hela cells MkjaSpVv[3Srb36gZZN{[Xl? MXm3NkBp MUfDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDh[pRmeiB5MjDodpMh[nliY3XscEBkd3WwdHnu[{whUUN3ME2wMlA2KM7:TR?= NVXMS3JFOjF6OUK4Nlk>
CEM/0 cells M1G0R2Z2dmO2aX;uJIF{e2G7 NUns[Ys3PzJiaB?= M{GyeWN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDSW0wOCClZXzsd{Bi\nSncjC3NkBpenNiYomgZ4VtdCClb4XueIlv\yxiSVO1NF0xNjB{MjFOwG0> M13iSVIyQDl{OEK5
L1210/0 cells NXrxWVd[TnWwY4Tpc44h[XO|YYm= NHTpRVk1QCCq M3joOGN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDMNVIyOC9yIHPlcIx{KGGodHXyJFQ5KGi{czDifUBk\WyuIHPveY51cW6pLDDJR|UxRTBwMECwPUDPxE1? Mlj2NlE5QTJ6Mkm=
MCF7 cells M4LZbGN6fG:2b4jpZ4l1gSCjc4PhfS=> MYi3NkBp MYnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDTVmIh[XO|YYmsJGlEPTB;MUKuNVkh|ryP NYTyZ2NWOjN6Nke2NFM>
HeLa cells MnjwR5l1d3SxeHnjbZR6KGG|c3H5 NF;uSYc4OiCq MUDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDTVmIh[XO|YYmsJGlEPTB;Nj61JO69VQ>? NE\tb40zOzh4N{[wNy=>
HL60 cells MV;Qdo9tcW[ncnH0bY9vKGG|c3H5 M4TT[FczKGh? MXPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiONkCgZ4VtdHNiYYPz[ZN{\WRiYYOg[5Jwf3SqIHnubIljcXSrb36gZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OD1yLkK0JO69VQ>? MkHYNlU3PDR4N{S=
SW707 cells MUPQdo9tcW[ncnH0bY9vKGG|c3H5 M37UcVczKGh? NF7wfHpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPXO|A4KGOnbHzzJIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9vKGGodHXyJFczKGi{czDifUBUWkJibXX0bI9lNCCLQ{WwQVI{Njh4IN88US=> MYiyOVY1PDZ5NB?=
LoVo cells MYXQdo9tcW[ncnH0bY9vKGG|c3H5 M2nQPFczKGh? M1LvN2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTH;Wc{Bk\WyuczDhd5Nme3OnZDDhd{Boem:5dHigbY5pcWKrdHnvckBi\nSncjC3NkBpenNiYomgV3JDKG2ndHjv[EwhUUN3ME2xPU4xPyEQvF2= NGCzPGEzPTZ2NE[3OC=>
BALB/3T3 cell NGixfFBRem:uaX\ldoF1cW:wIHHzd4F6 M4fDW|czKGh? NHrHWVRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JI1wfXOnIFLBUGIwO1R|IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDd{IHjyd{BjgSCVUlKgcYV1cG:mLDDJR|UxRTJ|Lkmg{txO NYnZRYR4OjV4NES2O|Q>
HFF cells MmXzSpVv[3Srb36gZZN{[Xl? M{f6OVczKGh? MlvVRY51cXCjcnHzbZRq[yCjY4Tpeol1gSCjZ3HpcpN1KFSxeH;wcIF{dWFiZ3;u[IlqKEGWQ1OgOVA5OzliaX7m[YN1\WRiaX6gTGZHKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDi[ZRiNWejbHHjeI9{cWSjc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhTUN3ME2wMlkyKM7:TR?= NYO4cZkzOTd4OUi2NVg>
CCRFCEM cells M1\2fmZ2dmO2aX;uJIF{e2G7 MVXDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1PSSmNGVSClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVA:OC5{OTFOwG0> MnLHNVc5ODR{M{G=
RXF393 cells MlvYSpVv[3Srb36gZZN{[Xl? NUnJVIVWPDhiaB?= M4rwe2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDSXGY{QTNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:Oy57OEGwO{DPxE1? Mn\tNVk4PDR6NUi=
HL-60(TB) cells M4W5VWZ2dmO2aX;uJIF{e2G7 NEjPbY01QCCq MWLBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFytOlApXEJrIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMUm5OVMh|ryP NELPO4UyQTd2NEi1PC=>
L1210 cells MoTiSpVv[3Srb36gZZN{[Xl? NYDL[IlMOTVibXnudy=> NIDKWW1KdmirYnn0bY9vKG:oIITofY1q\HmuYYTlJJN6dnSqYYPlJIlvKG2xdYPlJGwyOjFyIHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4YhfHKrdHn1cUBz\WynYYPlJIZzd21iW{WtN2he\GWxeIn1dollcW6nIHHmeIVzKHC{ZXnuZ5Vj[XSrb36g[o9zKDF3IH3pcpMh[nlibHnxeYllKHOlaX70bYxt[XSrb36gZ492dnSrbnesJGlEPTB;MD6wNFA3KM7:TR?= M{K0SFIyOzNyMEG0
Colo-357 cells NF[3c5JHfW6ldHnvckBie3OjeR?= MnjCNVAxKM7:TR?= NUXaTJNTOTVibXnudy=> MUTBZ5Rqfmm2eTDheEBOWlB3IHnuJIh2dWGwIFPvcI8uOzV5IHPlcIx{KGG|c3Xzd4VlKGG|IEWtSoRWVVBiYXPjeY12dGG2aX;uJIF1KDFyMDD1UUBi\nSncjCxOUBucW6| MWGyNFk{ODF{Mx?=
KB cells MVLDfZRwfG:6aXPpeJkh[XO|YYm= MUW3NkBp NIi3R5ZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMSiClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyPUiuOlkh|ryP MoHkNlM5Pjd4MEO=

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 49 mg/mL (199.03 mM)
Water 49 mg/mL (199.03 mM)
Ethanol '''10 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 246.19
Formula

C9H11FN2O5

CAS No. 50-91-9
Storage powder
in solvent
Synonyms Deoxyfluorouridine, FUDR
Smiles C1C(C(OC1N2C=C(C(=O)NC2=O)F)CO)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01042691 Completed Drug: Oxaliplatin Unresectable Colorectal Liver Metastases David Bartlett|The Pittsburgh Foundation|Sanofi|University of Pittsburgh May 2003 Phase 1
NCT00695201 Completed Drug: Floxuridine Oxaliplatin CPT-11 Colon Cancer|Rectal Cancer Memorial Sloan Kettering Cancer Center|University of Medicine and Dentistry of New Jersey|Rutgers The State University of New Jersey|Sanofi August 2000 Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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DNA/RNA Synthesis Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID