Floxuridine

Catalog No.S1299 Synonyms: Deoxyfluorouridine, FUDR, NSC 27640

Floxuridine Chemical Structure

Molecular Weight(MW): 246.19

Floxuridine is an antineoplastic antimetabolite, used in the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver.

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Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description Floxuridine is an antineoplastic antimetabolite, used in the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver.
In vitro

Floxuridine exhibits higher affinity for PEPT1 than the corresponding 5'-O-mono amino acid ester prodrugs. [1] Floxuridine combined with Leucovorin results in synergistic inhibitory effects on growth of human T-lymphoblast leukemia cells. [2] Floxuridine significantly inhibits the uptake of both [(3)H]-inosine and [(3)H]-adenosine (60-70% of control), while its amino acid ester prodrugs including Val, Phe, Pro, Asp, and Lys esters exhibits markedly decreased inhibition potency (10-30% of control). [3] Floxuridine inhibits cell proliferation by more than 50% relative to the untreated control cells at 36 days, the cell numbers still increases fourfold compared with the initial cell density. Floxuridine results in prolonged effects on the proliferation of human Tenon's capsule fibroblasts in vitro. [4] Floxuridine (FUDR) is an ideal drug for hepatic arterial infusion (HAI) due to its short half life, steep dose response curve, high total body clearance, and high hepatic extraction. [5]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
CCRF-CEM cell Mnn3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYHU[ZN1\WRiaX6geol1em9iZn;yJJRp\SCrbnjpZol1cW:wIH;mJINmdGxiZ4Lve5RpKG:oIHj1cYFvKFRibIntdIhw[myjc4TvbYQhS0OURj3DSW0h[2WubDDsbY5mKCiDVFPDJGNEVCBzMUmpMEBKSzVyPUCuOUDPxE1? M1fXPFEyQTB7N{G2
CCRF-CEM NH3SToJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHvJUYJKdiC4aYTyc{Bkd26lZX70doF1cW:wIILldZVqemWmIH\vdkA2OCViaX7obYJqfGmxbjDv[kBoem:5dHigc4YhcHWvYX6gcIV2c2WvaXGgZ4VtdCCuaX7lJGNEWkZvQ1XNJJdqfGhiaGDBVEApOC5{IIXubZQwdUxrLDDHTVUxRTBwMECwOkDPxE1? M2\WXVEyPTl5NEC0
LNCaP cells NHnWXXJEgXSxdH;4bYNqfHliYYPzZZk> NV;XRXFSS3m2b4TvfIlkKGOxbnPlcpRz[XSrb36gbY4heHKxc4TheIUhe3CnY3nmbYMh[W62aXflckApWFODKTDwdo9lfWOrbnegbJVu[W5iTF7DZXAh[2WubIOsJGlEPTB;MD6wOlkzKM7:TR?= M2n0d|EzOTZzMUW3
TSU cells NXn3WnNDS3m2b4TvfIlkcXS7IHHzd4F6 MX\DfZRwfG:6aXOgZ49v[2WwdILheIlwdiCrbjDuc44heHKxc4TheIUhe3CnY3nmbYMh[W62aXflckApWFODKTDwdo9lfWOrbnegbJVu[W5iVGPVJINmdGy|LDDJR|UxRTBwMEW4JO69VQ>? NVrFcop1OTJzNkGxOVc>
KBALB cell M4npWWN6fG:2b4jpZ4l1gSCjc4PhfS=> M2S0U2lvKH[rdILvJINmdGxiY4n0c5RwgGmlaYT5JIFo[Wmwc4SgT2JCVEJiY3XscEBtcW6nIDj0doFve2[xcn3l[EBncWK{b3LsZZN1KHOjcnPvcYEh[2WubDDsbY5mMSxiQ1O1NF03NjByRT2wOUDPxE1? NF3VNm4yOjZ{MEC3Oi=>
KBALB-STK cell MnXwR5l1d3SxeHnjbZR6KGG|c3H5 MmnITY4hfmm2cn:gZ4VtdCCleYTveI95cWOrdImgZYdicW6|dDDLRmFNSi2VVFugZ4VtdCCuaX7ld{BmgHC{ZYPz[YQhcW5iSGPWMVEhXEtuIFnDOVA:QC56MFWtNFUh|ryP MnTrNVI3OjByN{[=
L1210 mouse leukemia cells NXjXcllWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUKyOEBp MX\Hdo94fGhiaX7obYJqfGmxbjDpckBNOTJzMDDtc5V{\SCuZYXr[Y1q[SClZXzsd{Bi\nSncjCyOEBpKHS{ZXH0cYVvfCxiSVO1NF0xNjByNEGg{txO NGnzc2YyOTd{OEG5Ny=>
L1210 mouse leukemia cells NFr3eWRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoXnOFghcA>? MX3Hdo94fGhiaX7obYJqfGmxbjDpckBNOTJzMDDtc5V{\SCuZYXr[Y1q[SClZXzsd{Bi\nSncjC0PEBpeiC2cnXheI1mdnRuIFnDOVA:OC5yMEC2OEDPxE1? NGqwNJoyOTd{OEG5Ny=>
L5178Y cell NVXEOYlnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVXDc41x[XKjdHn2[UBqdmirYnn0bY9vKG:oIFy1NVc5YSClZXzsJIdzd3e2aDDpckB3cXS{bzCoZ49v[2WwdILheIlwdiC{ZYH1bZJm\CCob4KgOVAmKGmwaHnibZRqd25rLDDJR|UxRTBwMECwO|Yh|ryP MXG2O|c6ODB5
L5178Y cells MVrGeY5kfGmxbjDhd5NigQ>? M2LGXWlvcGmkaYTvdpkh[2:wY3XueJJifGmxbjDv[kBkd22yb4Xu[EB4[XNiY3HsZ5Vt[XSnZDDvckBNPTF5OGmgZ4VtdHNiYomgX|E1S12OZYWgbY5kd3Kyb4LheIlwdixiSVO1NF0zKM7:TR?= MljWPFI1PjJ{OR?=
L1210 mouse leukemia cells M2LEdGZ2dmO2aX;uJIF{e2G7 M1noTlIhcA>? NYHHVnVWXGi7bXnkfYxifGVic4nueIhie2ViaX7obYJqfGmxbjDpckBNOTJzMDDtc5V{\SCuZYXr[Y1q[SClZXzsd{Bi\nSncjCyJIhzKHS{ZXH0cYVvfCxiSVO1NF0xNjByN{mg{txO MlfsNVE4OjhzOUO=
LM cells NHPjO21HfW6ldHnvckBie3OjeR?= Mn;sNkBp NYnUTHh7XGi7bXnkfYxifGVic4nueIhie2ViaX7obYJqfGmxbjDpckB1cHmvaXTpcoUhc2mwYYPlJIRm\mmlaXXueEBNVSClZXzsd{Bi\nSncjCyJIhzKHS{ZXH0cYVvfCxiSVO1NF02NjRizszN NHnmbocyOTd{OEG5Ny=>
HT1080 cells NITzOVdHfW6ldHnvckBie3OjeR?= NFK3S3FEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTHQyODhyIHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OD1yLkG4JO69VQ>? MoLmNVc5ODR{M{G=
L1210 cells M{\zRWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYfpbI42PzJiaB?= NU[yVmxGS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KG2xdYPlJGwyOjFyIHPlcIx{KEGWQ1OgR2NNOjF7IHHzd4V{e2WmIHHzJIdzd3e2aDDy[YR2[3Srb36gZYZ1\XJiN{KgbJJ{NCCLQ{WwQVAvODF{IN88US=> NEfMUnMyPzl7N{OxPS=>
HL60 cells MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHnZW2E4OiCq M4fDZ2N6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIUFYxKGOnbHzzJGFVS0NiQ1PMJFI1OCCjc4Pld5Nm\CCjczDndo94fGhicnXkeYN1cW:wIHHmeIVzKDd{IHjyd{whUUN3ME2wMlAyOiEQvF2= NYDtNI9OOTd7OUezNVk>
CCRF-CEM cells MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVnZeJQ2PzJiaB?= M37jWmN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDR3JHNUOHTTDj[YxteyCDVFPDJGNEVCBzMUmgZZN{\XO|ZXSgZZMh\3Kxd4ToJJJm\HWldHnvckBi\nSncjC3NkBpenNuIFnDOVA:OC5yMUeg{txO M4DCNlE4QTl5M{G5
L1210 cells M3qxcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NW\OWld2PzJiaB?= MVXDfZRwe3SjdHnjJIFkfGm4aYT5JIlvKG2xdYPlJGwyOjFyIHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4Yh[2WubDDndo94fGhiYX\0[ZIhPzJiaILzMEBKSzVyPUCuNFEzKM7:TR?= M3fMOVE5ODd6N{W3
HL60 cells NXHRSG1ST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2fEflczKGh? MoSwR5l1d3O2YYTpZ{Bi[3Srdnn0fUBqdiCqdX3hckBJVDZyIHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4Yh[2WubDDndo94fGhiYX\0[ZIhPzJiaILzMEBKSzVyPUCuNFEzKM7:TR?= MW[xPFA4QDd3Nx?=
CCRF-CEM cells MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4jRc|czKGh? NHfr[VlEgXSxc4TheIlkKGGldHn2bZR6KGmwIHj1cYFvKEOFUl[tR2VOKGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCCpcn;3eIgh[W[2ZYKgO|IhcHK|LDDJR|UxRTBwMEG3JO69VQ>? MWqxPFA4QDd3Nx?=
CCRF-CEM cells MVXGeY5kfGmxbjDhd5NigQ>? MkHjOFghcA>? MnrRRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFPDVmYuS0WPIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEC2N|Eh|ryP MlzkNVk4PDR6NUi=
K562 cells M2[3TmZ2dmO2aX;uJIF{e2G7 NYjT[GVHPDhiaB?= M4nq[WFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvPzl2M{Og{txO MmqxNVk4PDR6NUi=
MOLT4 cells M{mx[GZ2dmO2aX;uJIF{e2G7 M{LtbVQ5KGh? M4P4VmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNU2xVPCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjB|OUixJO69VQ>? NXLYNVh3OTl5NES4OVg>
RPMI8266 cells M2nTfmZ2dmO2aX;uJIF{e2G7 NXu2XoRNPDhiaB?= NWnoVVgxSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHJRVUl6Mk[2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUCuO|k1OzNizszN M333eFE6PzR2OEW4
human SR cells NE\ERllHfW6ldHnvckBie3OjeR?= NETVZnk1QCCq MYPBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MD6wNVI2QSEQvF2= NXPKU|d4OTl5NES4OVg>
A549 cells Ml7ySpVv[3Srb36gZZN{[Xl? NEPC[IY1QCCq MnnGRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4xOTJ3OTFOwG0> MnKzNVk4PDR6NUi=
EKVX cells M2HvTmZ2dmO2aX;uJIF{e2G7 MnPUOFghcA>? MmPaRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFXLWngh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NVAh|ryP NXvme4FYOTl5NES4OVg>
HOP62 cells NF3BRWRHfW6ldHnvckBie3OjeR?= MnT4OFghcA>? NYXVUGx[SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhQWDZ{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEK1NVIh|ryP NVLxUW9JOTl5NES4OVg>
HOP92 cells MnT6SpVv[3Srb36gZZN{[Xl? MmPlOFghcA>? NGPD[YNCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTG9RQTJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC55OUSzN{DPxE1? M2nXblE6PzR2OEW4
NCI-H226 cells M1\ETWZ2dmO2aX;uJIF{e2G7 MV:0PEBp NVXyXYpUSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KMkK2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5 NV;XWZpJOTl5NES4OVg>
NCI-H23 NF\VOWJHfW6ldHnvckBie3OjeR?= NYXzV|ZuPDhiaB?= M{HK[WFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kuUDJ|IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFyIN88US=> MkHtNVk4PDR6NUi=
NCI-H322 M37Z[WZ2dmO2aX;uJIF{e2G7 MUO0PEBp NVi0eY14SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KM{KyUUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2wMlUxOTF7IN88US=> MmjsNVk4PDR6NUi=
NCI-H460 MlixSpVv[3Srb36gZZN{[Xl? NVTkSpZ6PDhiaB?= MULBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWg1PjBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC53MEGxPUDPxE1? MoDUNVk4PDR6NUi=
NCI-H522 NYTxemtSTnWwY4Tpc44h[XO|YYm= NIn2eHQ1QCCq NHPLZnhCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUmNKNUh3MkKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MD6wNFIh|ryP MXGxPVc1PDh3OB?=
COLO205 cells M{LVfmZ2dmO2aX;uJIF{e2G7 NHr6fGc1QCCq NXvJNG1FSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGNQVE9{MEWgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;Mj61NVE5QSEQvF2= MWqxPVc1PDh3OB?=
HCC2998 cells Mnv4SpVv[3Srb36gZZN{[Xl? MWe0PEBp NXi5XZRlSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhESzJ7OUigZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MT61PFQ5QSEQvF2= M1XyV|E6PzR2OEW4
HCT116 cells NGHUWYtHfW6ldHnvckBie3OjeR?= MlnwOFghcA>? Mni5RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFEyPiClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjByMTFOwG0> MV6xPVc1PDh3OB?=
HCT15 cells MofQSpVv[3Srb36gZZN{[Xl? MkXaOFghcA>? NVrMZ4xtSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhEXDF3IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMUK1PFkh|ryP M4mwbVE6PzR2OEW4
HT-29 cells MnfOSpVv[3Srb36gZZN{[Xl? M3yxNFQ5KGh? NEPzWXdCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTHQuOjliY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OS57OUWyOkDPxE1? MVmxPVc1PDh3OB?=
KM12 cells MoXvSpVv[3Srb36gZZN{[Xl? MoLxOFghcA>? M3vPRmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDLUVEzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVIvPTFzOEmg{txO MkixNVk4PDR6NUi=
SW620 cells MV3GeY5kfGmxbjDhd5NigQ>? NIGzc4g1QCCq NX;1OHFqSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNYPjJyIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTZwM{C5OVch|ryP NUHsNZRjOTl5NES4OVg>
SF268 cells MlrYSpVv[3Srb36gZZN{[Xl? NGPxTGI1QCCq M2LSTGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTSlI3QCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0yOCEQvF2= NXjPUo9tOTl5NES4OVg>
SF295 cells NGfHWIZHfW6ldHnvckBie3OjeR?= M{DTSFQ5KGh? NHHjZXJCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2YzQTViY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5yMUK1PUDPxE1? MoPlNVk4PDR6NUi=
SF539 cells M2\V[2Z2dmO2aX;uJIF{e2G7 Ml\ROFghcA>? M3r0U2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTSlU{QSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjB|OUixJO69VQ>? NXvwZoNFOTl5NES4OVg>
SNB19 cells NULocGtETnWwY4Tpc44h[XO|YYm= MVW0PEBp MYHBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU17CNVkh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NU46QTV{NjFOwG0> Mn3PNVk4PDR6NUi=
SNB75 cells NXfGcXdMTnWwY4Tpc44h[XO|YYm= NILtSY41QCCq MljuRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPORlc2KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvOTl7NUOg{txO NV3uVplIOTl5NES4OVg>
U251 cells NV\JOlZrTnWwY4Tpc44h[XO|YYm= MnfLOFghcA>? NIfscGJCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWVI2OSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjF{NUi5JO69VQ>? M1K3SFE6PzR2OEW4
LOXIMVI cells NE\2UGJHfW6ldHnvckBie3OjeR?= MlP3OFghcA>? M3XPSWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDMU3hKVV[LIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEK1NVIh|ryP MYOxPVc1PDh3OB?=
MALME-3M cells NGnR[XdHfW6ldHnvckBie3OjeR?= NX;ZTlFwPDhiaB?= M2fNXWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNRWxOTS1|TTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD15Lkm0N|I5KM7:TR?= M4\TUFE6PzR2OEW4
M14 cells Mlr2SpVv[3Srb36gZZN{[Xl? MkPtOFghcA>? NGqxXoNCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUVE1KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvOTV6NEmg{txO M{n6NlE6PzR2OEW4
SK-MEL-2 cells MVPGeY5kfGmxbjDhd5NigQ>? MlLROFghcA>? MUXBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU1utUWVNNTJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OTBizszN NUX6W4l[OTl5NES4OVg>
SK-MEL-28 cells MYTGeY5kfGmxbjDhd5NigQ>? NUXhdo83PDhiaB?= MlPrRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPLMW1GVC1{ODDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1zLkm5OVI3KM7:TR?= Mny3NVk4PDR6NUi=
SK-MEL-5 cells MV7GeY5kfGmxbjDhd5NigQ>? MV[0PEBp M1e0dGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTT{1OTUxvNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLkG5PVU{KM7:TR?= NHHrUIIyQTd2NEi1PC=>
UACC257 cells MUPGeY5kfGmxbjDhd5NigQ>? NH;Fdno1QCCq NX:zXmJJSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHVCS0N{NUegZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;Mz6xOlIzQCEQvF2= Ml[yNVk4PDR6NUi=
UACC62 cells NHywd4JHfW6ldHnvckBie3OjeR?= M2OwVVQ5KGh? NV3VfFJKSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHVCS0N4MjDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLkCzPVgyKM7:TR?= NGm4VnIyQTd2NEi1PC=>
IGROV1 cells M{nPNGZ2dmO2aX;uJIF{e2G7 M1:0bFQ5KGh? NWTzXItOSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGlIWk:YMTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1{LkWxNVg6KM7:TR?= MmHmNVk4PDR6NUi=
OVCAR-3 cells M1X4OmZ2dmO2aX;uJIF{e2G7 MVu0PEBp MmP2RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF;WR2FTNTNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:Oi53MUG4PUDPxE1? M{XFWlE6PzR2OEW4
OVCAR4 cells NHPpfVBHfW6ldHnvckBie3OjeR?= NFr5SnI1QCCq MXXBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iT2\DRXI1KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVExKM7:TR?= MlnVNVk4PDR6NUi=
OVCAR5 cells MVzGeY5kfGmxbjDhd5NigQ>? MmD2OFghcA>? MlLURY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF;WR2FTPSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF03NjNyOUW3JO6ddQ>? NWXDO5RCOTl5NES4OVg>
OVCAR8 cells M3nJfGZ2dmO2aX;uJIF{e2G7 MYG0PEBp NFvKcnhCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gU3ZESVJ6IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMUK1PFkh|ryP NY[5T4k2OTl5NES4OVg>
SKOV3 cells M{nTUWZ2dmO2aX;uJIF{e2G7 M17s[VQ5KGh? NVfK[Hd{SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNMV1Z|IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFwOUm1NlYh|ryP Mon1NVk4PDR6NUi=
786-0 cells M1qzRmZ2dmO2aX;uJIF{e2G7 MnHSOFghcA>? Ml:1RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIEe4Ok0xKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvOSEQvF2= MV2xPVc1PDh3OB?=
A498 cells NEHRdHRHfW6ldHnvckBie3OjeR?= NIiwUXk1QCCq MljERY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG0PVgh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NU4zPTh7MzFOwG0> NX\sUXI5OTl5NES4OVg>
ACHN cells MlW4SpVv[3Srb36gZZN{[Xl? M2DUdVQ5KGh? NX23NodwSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGFEUE5iY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5yM{G2NkDPxE1? MkPWNVk4PDR6NUi=
Caki1 cells MlzPSpVv[3Srb36gZZN{[Xl? NXvhVXByPDhiaB?= M{n3[2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDZYtqOSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjB|MU[yJO69VQ>? MUOxPVc1PDh3OB?=
SN12C cells M2PEXWZ2dmO2aX;uJIF{e2G7 NV[1bHF1PDhiaB?= NVvPRWdpSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNPOTKFIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMUm5OVMh|ryP NHH2d24yQTd2NEi1PC=>
TK10 cells NFPXdWpHfW6ldHnvckBie3OjeR?= M4nS[FQ5KGh? M4XlVGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDUT|ExKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVUvODFzOEeg{txO Ml\NNVk4PDR6NUi=
UO31 cells M2O4S2Z2dmO2aX;uJIF{e2G7 M162ZlQ5KGh? NFfteGRCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWW8{OSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjF{NUi5JO69VQ>? MXOxPVc1PDh3OB?=
PC3 cells M3PrcWZ2dmO2aX;uJIF{e2G7 MVu0PEBp NW\6RVY5SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHBEOyClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjNzNkKzJO69VQ>? MWGxPVc1PDh3OB?=
DU145 cells M3XnS2Z2dmO2aX;uJIF{e2G7 MYS0PEBp M4rqSmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDEWVE1PSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjJ3MUG5JO69VQ>? MVyxPVc1PDh3OB?=
MCF7 cells NYjoOoN2TnWwY4Tpc44h[XO|YYm= MXe0PEBp M17PZmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvODB4M{Gg{txO NWi0S242OTl5NES4OVg>
NCI/ADR-RES cells Mk\5SpVv[3Srb36gZZN{[Xl? Mk\pOFghcA>? NVrrdpYySW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG5EUS:DRGKtVmVUKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVEvOjV6OUOg{txO M4DE[VE6PzR2OEW4
MDA-MB-231 cells NWLVVow{TnWwY4Tpc44h[XO|YYm= MlixOFghcA>? NILWZ4pCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2zMlk5OTB5IN88US=> MlGzNVk4PDR6NUi=
Hs 578T cells MXTGeY5kfGmxbjDhd5NigQ>? M1HsdVQ5KGh? NITlT4hCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTJMhPTd6VDDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1|Lkm4NVA4KM7:TR?= MY[xPVc1PDh3OB?=
MDA-MB-435 cells M{f5[GZ2dmO2aX;uJIF{e2G7 MljjOFghcA>? MlvERY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi12M{WgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;Mz6xOlIzQCEQvF2= M1\nTVE6PzR2OEW4
MDA-N cells NHXPbYhHfW6ldHnvckBie3OjeR?= MVu0PEBp M2C3VmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuViClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0yNjJ3OEmzJO69VQ>? NFu1WYYyQTd2NEi1PC=>
BT549 cells NI\NfJNHfW6ldHnvckBie3OjeR?= Mon2OFghcA>? NYm1RXFZSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGJVPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFizszN NXrOPFNtOTl5NES4OVg>
T47D cells M{nPN2Z2dmO2aX;uJIF{e2G7 MV60PEBp NIDvboFCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWFQ4TCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0yNjJ3OEmzJO69VQ>? M3:0V|E6PzR2OEW4
HepG2 cells MmX5R5l1d3SxeHnjbZR6KGG|c3H5 NUjzSod5PzJiaB?= NHn4[YdEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCHQ{WwQVE5Njh2IN88US=> NIjmWIYyQTlzN{WyPC=>
A549 cells M{foVGN6fG:2b4jpZ4l1gSCjc4PhfS=> NV;scpJ3PzJiaB?= NVmwfW0{S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCHQ{WwQVkvPzRizszN NVzISWprOTl7MUe1Nlg>
LAC cells Mlv3R5l1d3SxeHnjbZR6KGG|c3H5 MnfUO|IhcA>? M2nsRWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGxCSyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBGSzVyPUOyMlA6KM7:TR?= MVWxPVkyPzV{OB?=
HeLa cells MUjDfZRwfG:6aXPpeJkh[XO|YYm= Mnv0O|IhcA>? NInJNGZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEWFNUC9NVAvOjZizszN MoPaNVk6OTd3Mki=
MDA-MB-231 cells Mn;rR5l1d3SxeHnjbZR6KGG|c3H5 M{HVSmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj2yN|Eh[2WubIOgc5ZmemW6cILld5NqdmdidYLvb4lv[XOnIIDsZZNucW6xZ3XuJIFkfGm4YYTvdkwhUUN3ME2wMlIyKM7:TR?= NEX6eY4zODN4M{GzNC=>
human ACHN cells MnzWSpVv[3Srb36gZZN{[Xl? NGLQOYZCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gRWNJViClZXzsd{BjgSCVUlKgZZN{[XluIFfJOVA:Oi5zIN88US=> Mle1NlA4OzJ6MUC=
PC3 cells NF3mbZJHfW6ldHnvckBie3OjeR?= M1[1XGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZpkhW1KEIHHzd4F6NCCJSUWwQVQvQTdizszN MUmyNFc{OjhzMB?=
MDA-MB-231 cells NFjDOoNHfW6ldHnvckBie3OjeR?= MULBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTJ|MTDj[YxteyCkeTDTVmIh[XO|YYmsJGdKPTB;MD6xOkDPxE1? M3u4VFIxPzN{OEGw
FM3A cells MVLGeY5kfGmxbjDhd5NigQ>? MX[yJIRigXN? NU\hdGlQS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KG2xdYPlJGZOO0FiY3XscJMh[W[2ZYKgNkBl[Xm|IHL5JINwfWy2ZYKgZ492dnSrbnegZY5idHm|aYOsJGlEPTB;MD6wNFk1KM7:TR?= NFXOWHAzOTN|MECxOC=>
HeLa cells NXG2d4NyTnWwY4Tpc44h[XO|YYm= NGPnfGtEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{BqdiCycnXz[Y5k\SCxZjCyNEB2VSC2aIntbYRqdmVuIFnDOVA:QC53IN88US=> NX6yN2ZNOjF|M{CwNVQ>
LLC cells NYWzS4Y1S3m2b4TvfIlkcXS7IHHzd4F6 MU[yOEBp M17oPGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KG2xdYPlJGxNSyClZXzsd{Bi\nSncjCyOEBpenNiYomgdoV{[Xq3cnnuJIF{e2G7LDDJR|UxRTF2LkKg{txO NYXzeWFEOjF3M{[0OFg>
LLC cells NEXUVZREgXSxdH;4bYNqfHliYYPzZZk> MX[3NkBp NFjrWpVEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBNVENiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JJJme2G8dYLpckBie3OjeTygTWM2OD1{IN88US=> MWWyNVU{PjR2OB?=
RAW264.7 cells MXPDfZRwfG:6aXPpeJkh[XO|YYm= NUjIWHhqPzJiaB?= MlnuR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgVmFYOjZ2LkegZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KHKnc3H6eZJqdiCjc4PhfUwhUUN3ME2zNEDPxE1? M4nzd|IyPTN4NES4
A549 cells MonLR5l1d3SxeHnjbZR6KGG|c3H5 NHnBdmY4OiCq NEHPNZlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGG|c3Xzd4VlKGG|IHPlcIwhfmmjYnnsbZR6KGGodHXyJFczKGi{czDifUBYW1RvODDhd5NigSxiSVO1NF0xNjB2NzFOwG0> NVvwWIltOjJ{NEi4OVY>
A2780 cells M2\ubGN6fG:2b4jpZ4l1gSCjc4PhfS=> M4DvZ|Uh\GG7cx?= NF3Pd5VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCOjd6MDDj[YxteyCjZoTldkA2KGSjeYOgZpkhVVSWIHHzd4F6NCCLQ{WwQVAvODJ4IN88US=> NVPJeVg2OjJ5M{i2N|Y>
LMTK cells NXTaZlluS3m2b4TvfIlkcXS7IHHzd4F6 M1exclUh\GG7cx?= MlrrR5l1d3SxeHnjbZR6KGGpYXnud5QhfGi7bXnkbY5mKGurbnHz[U1l\W[rY3nlcpQhdW:3c3WgUG1VUyClZXzsd{Bi\nSncjC1JIRigXNiYomgUXRVKGG|c3H5MEBKSzVyPUSuOUDPxE1? NITkeoczOjd|OE[zOi=>
A549 cells NHnvbnVEgXSxdH;4bYNqfHliYYPzZZk> MnTvO|IhcA>? NXy0ZosyS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA4OiCqcoOgZpkhdWmlcn;wcIF1\SC{ZXHk[ZIhdWW2aH;kMEBKSzVyPUCuNFEzPCEQvF2= NWq4Sm9IOjJ6NEewNVk>
CEM cells M2TkOWZ2dmO2aX;uJIF{e2G7 M{jvWlczKGh? MWXDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1XNJINmdGy|IHX4dJJme3OrbnegbJVu[W5iRV7UNUB1emGwc4DvdpRmeiCjZoTldkA4OiCqcoOgZpkh[2WubDDjc5VvfGmwZzDpckBxemW|ZX7j[UBw\iCQQl3QVkwhUUN3ME2wMlgh|ryP M{X0WFIyQDl{OEK5
Hela cells NEPiXm1HfW6ldHnvckBie3OjeR?= NIPESpI4OiCq M{jmUGN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDj[YxtKGOxdX70bY5oNCCLQ{WwQVAvODVizszN MXWyNVg6Ojh{OR?=
CEM/0 cells NUXuPYVETnWwY4Tpc44h[XO|YYm= NULpVnlSPzJiaB?= NXPHRo5TS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGNGVS9yIHPlcIx{KGGodHXyJFczKGi{czDifUBk\WyuIHPveY51cW6pLDDJR|UxRTBwMEKyJO69VQ>? NHjXXG4zOTh7MkiyPS=>
L1210/0 cells MlTsSpVv[3Srb36gZZN{[Xl? M3roZlQ5KGh? MoLUR5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JI1wfXOnIFyxNlExNzBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JINmdGxiY3;1cpRqdmduIFnDOVA:OC5yMEC5JO69VQ>? M4jDc|IyQDl{OEK5
MCF7 cells MoXLR5l1d3SxeHnjbZR6KGG|c3H5 NELyPJY4OiCq NGjRb3hEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUC9NVIvOTlizszN NWf3ZZZ{OjN6Nke2NFM>
HeLa cells NYXyXJN4S3m2b4TvfIlkcXS7IHHzd4F6 NW\CXnJsPzJiaB?= NYHCRZd2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjZoTldkA4OiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwQVYvPSEQvF2= NILUe|IzOzh4N{[wNy=>
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RXF393 cells MV;GeY5kfGmxbjDhd5NigQ>? NU\jNJJJPDhiaB?= NFfHUI9CdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gVnhHOzl|IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTNwOUixNFch|ryP MYCxPVc1PDh3OB?=
HL-60(TB) cells M2PvOGZ2dmO2aX;uJIF{e2G7 MnnuOFghcA>? NVn6W5ZTSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhNNTZyKGTCLUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2wMlE6QTV|IN88US=> NUDoN2JWOTl5NES4OVg>
L1210 cells NH;D[WhHfW6ldHnvckBie3OjeR?= M4rYN|E2KG2rboO= NUj0XZB1UW6qaXLpeIlwdiCxZjD0bJlucWS7bHH0[UB{gW62aHHz[UBqdiCvb4Xz[UBNOTJzMDDj[YxteyCjc4Pld5Nm\CCjczDpcohq[mm2aX;uJI9nKHS{aYTpeY0hemWuZXHz[UBnem:vIGu1MVNJZWSnb4j5eZJq\GmwZTDh[pRmeiCycnXpcoN2[mG2aX;uJIZweiBzNTDtbY5{KGK7IHzpdZVq\CC|Y3nueIltdGG2aX;uJINwfW62aX7nMEBKSzVyPUCuNFAxPiEQvF2= MkPCNlE{OzByMUS=
Colo-357 cells NIf5fmlHfW6ldHnvckBie3OjeR?= NWPkW3NYOTByIN88US=> Ml\RNVUhdWmwcx?= MVLBZ5Rqfmm2eTDheEBOWlB3IHnuJIh2dWGwIFPvcI8uOzV5IHPlcIx{KGG|c3Xzd4VlKGG|IEWtSoRWVVBiYXPjeY12dGG2aX;uJIF1KDFyMDD1UUBi\nSncjCxOUBucW6| M1z2OFIxQTNyMUKz
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... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 49 mg/mL (199.03 mM)
Water 49 mg/mL (199.03 mM)
Ethanol 10 mg/mL (40.61 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 246.19
Formula

C9H11FN2O5

CAS No. 50-91-9
Storage powder
in solvent
Synonyms Deoxyfluorouridine, FUDR, NSC 27640

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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DNA/RNA Synthesis Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID